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Results from the synthesis of sexithiophene carrying chiral (2S)-2-methyl-3,6,9,12,15-pentaoxahexadecyl esters at the alpha and omega positions are presented and its supramolecular organization in protic solvents is discussed.

In this report, we describe the case of a 64-year-old male patient, with no history of alcohol consumption, who presented the Osler's triad, which is the association of endocarditis, pneumonia, and meningitis caused by a single agent. This syndrome is called Austrian syndrome, when the infection is caused by Streptococcus pneumoniae. We discuss the clinical manifestations, the pathophysiology, and the therapeutic approach to this condition. Given the rarity of the condition and its high morbidity and mortality, the importance of an early diagnosis and an appropriate treatment to reduce the complications associated with this disease will be emphasized.

The non-aggregating nature of a water-soluble pi-conjugated polythiophene has been characterised by concentration independent thermal denaturing.

The action of FeCl(3) on 3-(alkylsulfanyl)thiophenes (3-(alkylthio)thiophenes) leads to the one-step formation of regioregular alpha-conjugated oligothiophenes, from trimer to octamer, depending on the solvent used and on the length of the alkyl chain. The regiochemistry of these oligomers is characterized by one inner head-to-head linkage between adjacent rings and by a variable number of lateral head-to-tail junctions. The reaction of ferric chloride with the head-to-head and head-to-tail bis(methylsulfanyl)-2,2'-bithiophenes gives the corresponding tetramers, while the reaction with the tail-to-tail counterpart affords a high molecular weight insoluble material. With the aid of theoretical calculations, these results are interpreted on the basis of the joint effects of the orienting power of the substituents and of the stability of the radical cations formed during the oxidative process.