Search

Your search keyword '"Gabbriellini, Giovanna"' showing total 15 results
Start Over Author "Gabbriellini, Giovanna"
15 results on '"Gabbriellini, Giovanna"'

5. The Management of Dry Eye Disease: Proceedings of Italian Dry Eye Consensus Group Using the Delphi Method

Author

Aragona, Pasquale, primary, Giannaccare, Giuseppe, additional, Mencucci, Rita, additional, Rubino, Pierangela, additional, Cantera, Emilia, additional, Finocchiaro, Claudia Yvonne, additional, Vaccaro, Sabrina, additional, Aiello, Francesco, additional, Antoniazzi, Elena, additional, Barabino, Stefano, additional, Bonini, Stefano, additional, Carlini, Gianpaolo, additional, Chierego, Chiara, additional, Gisoldi, Rossella Anna Maria Colabelli, additional, Di Zazzo, Antonio, additional, Fasciani, Romina, additional, Franch, Antonella, additional, Gabbriellini, Giovanna, additional, Gagliano, Caterina, additional, Leonardi, Andrea, additional, Macrì, Angelo, additional, Mosca, Luigi, additional, Orfeo, Vincenzo, additional, Pinna, Antonio, additional, Pocobelli, Augusto, additional, Protti, Romolo, additional, Rama, Paolo, additional, Rania, Laura, additional, Rechichi, Miguel, additional, Russo, Andrea, additional, Scorcia, Vincenzo, additional, Spadea, Leopoldo, additional, Trentadue, Marco, additional, Troisi, Salvatore, additional, Versura, Piera, additional, Villani, Edoardo, additional, and Rolando, Maurizio, additional

Published
2022
Full Text
View/download PDF

8. Biological parameters determining the clinical outcome of autologous cultures of limbal stem cells

Author

Pellegrini, Graziella, Rama, Paolo, Matuska, Stanislav, Lambiase, Alessandro, Bonini, Stefano, Pocobelli, Augusto, Colabelli, Rossella Gisoldi, Spadea, Leopoldo, Fasciani, Romina, Balestrazzi, Emilio, Vinciguerra, Paolo, Rosetta, Pietro, Tortori, Achille, Nardi, Marco, Gabbriellini, Giovanna, Traverso, Carlo E, Macaluso, Claudio, Losi, Lorena, Percesepe, Antonio, Venturi, Beatrice, Corradini, Francesca, Panaras, Athanasios, Di Rocco, Antonio, Guatelli, Paolo, and De Luca, Michele

Published
2013
Full Text
View/download PDF

11. Fabry disease due to G171S GLAmutation: An atypical small nerve fiber sparing variant?

Author

Prencipe, Matteo, Posarelli, Chiara, Figus, Michele, and Gabbriellini, Giovanna

Abstract

Introduction: To describe the ocular manifestations and in vivo confocal microscopic findings in a patient carrying the recently described hemizygous G171S GLAgene mutation.Case description: A 63-year-old Albanian male patient was evaluated for cataract surgery. Anamnesis showed pacemaker implantation in left ventricular hypertrophy, chronic kidney disease, family history for kidney transplantation, and late onset of sporadic acroparesthesias. Bilateral cornea verticillata, and increased tortuosity in conjunctival and retinal vessels were present. In vivo confocal microscopy revealed clusters of hyper-reflective corneal epithelial cells centripetally extending from the limbus. Interestingly, the nerve fiber number, density, and length in the corneal sub-basal nerve plexus were preserved. Alpha-galactosidase A activity was almost absent and hemizygous c.511G>A mutation (G171S – p.Gly171Ser) of the GLAgene was identified. The patient was referred for initiation of enzyme replacement therapy, and genetic counseling was recommended for at-risk family members.Conclusion: This is the third reported case of Fabry disease due to GLAG171S mutation. All patients are of Albanian descent. Cornea verticillata and vascular anomalies remain common ocular manifestations, as well as cardiac and renal involvement. Confirming its pathogenicity, this mutation results in a “classic” Fabry disease phenotype, but it seems to be associated with a relative small nerve fiber sparing that may delay a correct diagnosis. The diagnosis of Fabry disease still remains challenging due to its clinical heterogeneity, but a thorough ophthalmological examination can promote early detection and, consequently, early initiation of enzyme replacement therapy.

Published
2021
Full Text
View/download PDF

12. In vivo confocal scanning laser microscopy in patients with primary Sjögren's syndrome: A monocentric experience

Author

Gabbriellini, Giovanna, primary, Baldini, Chiara, additional, Varanini, Valentina, additional, Notarstefano, Chiara, additional, Pepe, Pasquale, additional, Fanucci, Francesca, additional, Ferro, Francesco, additional, Luciano, Nicoletta, additional, Mosca, Marta, additional, Nardi, Marco, additional, and Bombardieri, Stefano, additional

Published
2014
Full Text
View/download PDF

13. In vivo confocal scanning laser microscopy in patients with primary Sjögren's syndrome: A monocentric experience.

Author

Gabbriellini, Giovanna, Baldini, Chiara, Varanini, Valentina, Notarstefano, Chiara, Pepe, Pasquale, Fanucci, Francesca, Ferro, Francesco, Luciano, Nicoletta, Mosca, Marta, Nardi, Marco, and Bombardieri, Stefano

Subjects
*LASER microscopy, *SJOGREN'S syndrome, *DRY eye syndromes, *EPITHELIAL cells, *LACRIMAL apparatus
Abstract

Aims. (i) To analyze the in vivo corneal structure and sub-basal plexus nerves in patients with primary Sjögren's syndrome (pSS) and no-SS dry eye by confocal scanning laser microscopy (CSLM) and (ii) to correlate CSLM findings with tear function tests and with patients' subjective dryness. Methods. Seventeen patients with pSS, 16 no-SS dry eye, and 20 healthy volunteers were included. CSLM parameters taken into consideration included: basal epithelial integrity, corneal thickness, epithelial cellular density, keratocyte activation, and sub-basal plexus morphology. Statistical analysis was carried out using SPSS-13 (Chicago IL, USA). Results. CSLM pachymetric data and the superficial epithelium cell density were significantly lower in pSS versus no-SS dry eye ( p < 0.0001); keratocyte activation and sub-basal nerve abnormalities were also more frequent in pSS patients ( p < 0.0001). CSLM findings well correlated with both the ocular test results and the patients' perception of ocular dryness at the baseline and over the follow-up. Conclusion. CSLM might be a useful novel tool in the assessment of the involvement of the lachrymal functional unit in pSS. [ABSTRACT FROM AUTHOR]

Published
2015
Full Text
View/download PDF

14. The Management of Dry Eye Disease: Proceedings of Italian Dry Eye Consensus Group Using the Delphi Method

Author

Pasquale Aragona, Giuseppe Giannaccare, Rita Mencucci, Pierangela Rubino, Emilia Cantera, Claudia Yvonne Finocchiaro, Sabrina Vaccaro, Francesco Aiello, Elena Antoniazzi, Stefano Barabino, Stefano Bonini, Gianpaolo Carlini, Chiara Chierego, Rossella Anna Maria Colabelli Gisoldi, Antonio Di Zazzo, Romina Fasciani, Antonella Franch, Giovanna Gabbriellini, Caterina Gagliano, Andrea Leonardi, Angelo Macrì, Luigi Mosca, Vincenzo Orfeo, Antonio Pinna, Augusto Pocobelli, Romolo Protti, Paolo Rama, Laura Rania, Miguel Rechichi, Andrea Russo, Vincenzo Scorcia, Leopoldo Spadea, Marco Trentadue, Salvatore Troisi, Piera Versura, Edoardo Villani, Maurizio Rolando, Aragona, Pasquale, Giannaccare, Giuseppe, Mencucci, Rita, Rubino, Pierangela, Cantera, Emilia, Finocchiaro, Claudia Yvonne, Vaccaro, Sabrina, Aiello, Francesco, Antoniazzi, Elena, Barabino, Stefano, Bonini, Stefano, Carlini, Gianpaolo, Chierego, Chiara, Gisoldi, Rossella Anna Maria Colabelli, Di Zazzo, Antonio, Fasciani, Romina, Franch, Antonella, Gabbriellini, Giovanna, Gagliano, Caterina, Leonardi, Andrea, Macrì, Angelo, Mosca, Luigi, Orfeo, Vincenzo, Pinna, Antonio, Pocobelli, Augusto, Protti, Romolo, Rama, Paolo, Rania, Laura, Rechichi, Miguel, Russo, Andrea, Scorcia, Vincenzo, Spadea, Leopoldo, Trentadue, Marco, Troisi, Salvatore, Versura, Piera, Villani, Edoardo, and Rolando, Maurizio

Subjects
n/a, Settore MED/30 - Malattie Apparato Visivo, Dry Eye Disease, consensus group, delphy method, clinical practice, General Medicine
Abstract

Dry eye disease (DED) is a highly prevalent, chronic and progressive condition that affects 5–33% of the world’s adult population [...]

Published
2022

15. Ocular Surface Disease Index (OSDI): a potential useful instrument for the assessment of vision-targeted health-related quality of life (VT-HRQ) in primary Sjögren's syndrome (pSS) clinical trials?

Author

Gabbriellini G, Baldini C, Varanini V, Ferro F, Pepe P, Luciano N, Fanucci F, Mosca M, Nardi M, and Bombardieri S

Subjects
Adult, Aged, Analysis of Variance, Case-Control Studies, Chi-Square Distribution, Dry Eye Syndromes physiopathology, Dry Eye Syndromes psychology, Dry Eye Syndromes therapy, Female, Humans, Middle Aged, Predictive Value of Tests, Prospective Studies, Severity of Illness Index, Sjogren's Syndrome physiopathology, Sjogren's Syndrome psychology, Sjogren's Syndrome therapy, Treatment Outcome, Clinical Trials as Topic methods, Dry Eye Syndromes diagnosis, Quality of Life, Research Design, Sjogren's Syndrome diagnosis, Surveys and Questionnaires, Vision, Ocular
Published
2012

Catalog

Books, media, physical & digital resources
See catalog results