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32 results on '"Gaddam, Krishna K."'

6. Spironolactone Reduces Aortic Stiffness in Patients With Resistant Hypertension Independent of Blood Pressure Change

Author

Aryal, Sudeep R., primary, Siddiqui, Mohammed, additional, Sharifov, Oleg F., additional, Coffin, Megan D., additional, Zhang, Bin, additional, Gaddam, Krishna K., additional, Gupta, Himanshu, additional, Denney, Thomas S., additional, Dell'Italia, Louis J., additional, Oparil, Suzanne, additional, Calhoun, David A., additional, and Lloyd, Steven G., additional

Published
2021
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17. RAPID IMPROVEMENT IN AORTIC DISTENSIBILITY AND PULSATILITY WITH SPIRONOLACTONE THERAPY IN PATIENTS WITH RESISTANT HYPERTENSION: A CARDIAC MRI STUDY

Author

Esfahani, Fatemeh Bagheriannejad, primary, Aggarwal, Himanshu, additional, Manapragada, Padmapriya, additional, Gaddam, Krishna K., additional, Schiros, Chun G., additional, Zha, Wei, additional, Ahmed, Mustafa, additional, Agarwal, Shilpi, additional, Gupta, Himanshu, additional, Denney, Thomas S., additional, Dell’Italia, Louis J., additional, Calhoun, David A., additional, and Lloyd, Steven G., additional

Published
2011
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20. Abstract 4853: Spironolactone Therapy is Associated With Rapid Improvements in Blood Pressure Control and Cardiac Remodeling in Patients With Resistant Hypertension

Author

Ahmed, Mustafa I, primary, Gaddam, Krishna K, additional, Gladden, James D, additional, Desai, Ravi V, additional, Lloyd, Steven G, additional, Gupta, Himanshu, additional, Denney, Thomas S, additional, Oparil, Suzanne, additional, Dell’Italia, Louis J, additional, and Calhoun, David A, additional

Published
2009
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30. Characterization of Resistant Hypertension Association Between Hypertension, Aldosterone, and Persistent Intravascular Volume Expansion.

Author

Gaddam, Krishna K., Nishizaka, Mari K., Pratt-Ubunama, Monique N., Pimenta, Eduardo, Aban, Inmaculada, Oparil, Suzanne, and Calhoun, Davia A.

Subjects
*HYPERTENSION, *BLOOD circulation disorders, *PATIENTS, *ATRIAL natriuretic peptides, *ALDOSTERONE, *RENIN, *HYDROCORTISONE, *SODIUM, *POTASSIUM, *DISEASE risk factors, *THERAPEUTICS, *DISEASES
Abstract

The article examines the connection between resistant hypertension, aldosterone, and persistent intravascular volume expansion. Characteristics of 279 consecutive patients with resistant hypertension and 53 control subjects are evaluated in the study. Participants of the study are observed for plasma aldosterone concentration, plasma renin activity, aldosterone to renin ratio, brain-type natriuretic peptide, atrial natriuretic peptide, and 24-hour urinary aldosterone, cortisol, sodium, and potassium values while continuously doing a routine diet. It concludes that patients with resistant hypertension have higher aldosterone levels and intravascular volume expansion than those patients with controls.

Published
2008
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31. Renin inhibition should it supplant ACE inhibitors and ARBS in high risk patients

Author

Gaddam, Krishna K and Oparil, Suzanne

Abstract

The direct renin inhibitor aliskiren has recently been approved for the treatment of hypertension in humans. The potential for these newer agents having an advantage over the existing renin–angiotensin–aldosterone system (RAAS) antagonists in the treatment of hypertension and related target organ damage has drawn the interest of several investigators. In this review, we discuss the potential advantages and disadvantages of this newest antihypertensive class over other available RAAS antagonists.

Published
2008
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32. Advanced heart failure and management strategies.

Author

Gaddam KK, Yelamanchili P, Sedghi Y, and Ventura HO

Abstract

The global healthcare burden attributable to heart failure is ever increasing. Patients presenting with refractory heart failure should be evaluated for compliance with medical regimens and sodium and/or fluid restriction, and every attempt should be made to optimize conventional strategies. Reversible causes such as ischemia should be identified and revascularization considered in persistently symptomatic patients, particularly those with a viable myocardium. Carefully selected patients who continue to deteriorate clinically in spite of optimization of medical therapy may be considered for advanced treatment strategies, such as continuous inotropic infusions, mechanical circulatory support devices, cardiac transplantation, or referral to hospice care. We discuss the clinical presentation and management of patients with advanced/refractory (Stage D) heart failure.

Published
2009

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