5 results on '"Gadoury-Lévesque V"'
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2. A CASE OF REFRACTORY RECURRENT CYCLICAL ANGIOEDEMA AND URTICARIA SUCCESSFULLY TREATED WITH MULTIPLE STEPS THERAPY
- Author
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Gadoury-Levesque, V. and Bernstein, J.
- Published
- 2018
- Full Text
- View/download PDF
3. Bridging knowledge gaps in paediatric chronic urticaria through a video-based educational tool.
- Author
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Karim J, Gabrielli S, Mule P, Torabi B, Byrne A, De Schryver S, Gadoury-Lévesque V, Alizadehfar R, McCusker C, Zhang X, and Ben-Shoshan M
- Subjects
- Male, Female, Humans, Child, Infant, Child, Preschool, Adolescent, Ambulatory Care Facilities, Chronic Urticaria, Urticaria therapy
- Abstract
Background: There is a lack of patient educational resources about chronic urticaria (CU)., Aims: To develop and test the effectiveness of an education tool to help paediatric patients and their families better understand CU and its management., Methods: From July 2020 to May 2022, paediatric patients with a history of CU who presented to the allergy outpatient clinics at our institution were recruited. Consenting families and patients were asked to complete five questions related to the definition, causes and management of CU at the time of presentation to the clinic. Participants were shown a 5-min animated video addressing the main knowledge gaps about CU. At the end of the video, participants were redirected to the same five questions to respond again. The scores were recorded as a proportion of correct answers (range 0·0-1·0)., Results: In total, 53 patients [30 girls (56·6%), 23 boys (43·4%); mean age 9·7 ± 5·1 years, range 1·4-18·5 years] were recruited. The mean baseline pre-video education questionnaire score was 0·67 ± 0·2 (range 0·2-1·0), while the mean post-video score was 0·94 ± 0·1 (range 0·4-1·0), a mean score difference of 0·27, which was statistically significant (P < 0·001). At the 1-year follow-up, 14 (26·4%) patients answered the questionnaire again to assess retention of knowledge; the mean score was 0·83 ± 0·2 (range 0·2-1·0)., Conclusions: Our educational video was successful in educating patients and their families to better understand urticaria. Future studies should aim to optimize patient education through nontraditional tools such as videos, and compare knowledge gain using different methods of education., Competing Interests: Conflict of interest The authors declare that they have no conflict of interest., (© The Author(s) 2022. Published by Oxford University Press on behalf of British Association of Dermatologists. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Published
- 2023
- Full Text
- View/download PDF
4. Bridging Knowledge Gaps in Anaphylaxis Management Through a Video-Based Educational Tool.
- Author
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Karim J, Gabrielli S, Torabi B, Byrne A, De Schryver S, Gadoury-Lévesque V, Alizadehfar R, McCusker C, Vincent M, Morris J, Gerdts J, Zhang X, and Ben-Shoshan M
- Subjects
- Male, Humans, Child, Infant, Child, Preschool, Adolescent, Female, Surveys and Questionnaires, Educational Status, Anaphylaxis drug therapy, Anaphylaxis etiology, Food Hypersensitivity complications, Food Hypersensitivity drug therapy, Communications Media
- Abstract
Introduction: We aimed to develop and test the effectiveness of an education tool to help pediatric patients and their families better understand anaphylaxis and its management, and to improve current knowledge and treatment guidelines adherence. Methods: From June 2019 to May 2022, 128 pediatric patients with history of food-triggered anaphylaxis who presented to the allergy outpatient clinics at the study institution were recruited. Consenting families were asked to complete 6 questions related to the triggers, recognition, and management of anaphylaxis at the time of presentation to the clinic. Participants were shown a 5-min animated video on the causes, presentation, and management of anaphylaxis. At the end of the video, the participants were redirected to the same 6 questions to respond again. The scores were recorded in proportion of correct answers (minimum 0.0; maximum 1.0). Results: The mean age of the patients was 5.8 ± 4.5 years (range: 0.5-18.8 years). The majority were males (70 patients; 54.7%). The mean baseline prevideo education questionnaire score was 0.76 ± 0.2 (range: 0.3-1.0), whereas the mean follow-up score was 0.82 ± 0.2 (range: 0.3-1.0). This score difference of 0.06 was statistically significant ( P < 0.001). There were no significant associations between change in scores and age or gender of the participants. Conclusion: Our video teaching method was successful in educating patients and their families to better understand anaphylaxis and its management at the moment of the clinical encounter. Retention of knowledge at long-term follow-up should be assessed.
- Published
- 2022
- Full Text
- View/download PDF
5. Peanut oral immunotherapy in a pediatric allergy clinic: Patient factors associated with clinical outcomes.
- Author
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Guarnieri KM, Slack IF, Gadoury-Lévesque V, Eapen AA, Andorf S, and Lierl MB
- Subjects
- Administration, Oral, Adolescent, Antigens, Plant immunology, Child, Child, Preschool, Female, Humans, Immunoglobulin E immunology, Male, Peanut Hypersensitivity immunology, Antigens, Plant administration & dosage, Arachis immunology, Desensitization, Immunologic methods, Patient Compliance statistics & numerical data, Peanut Hypersensitivity therapy
- Abstract
Background: Additional information is needed to inform optimal patient selection, expected outcomes, and treatment end points for clinical peanut oral immunotherapy (OIT)., Objective: To provide insight into the optimal patient selection, expected outcomes, and treatment end points for clinical peanut oral immunotherapy by analyzing a real-world peanut OIT cohort., Methods: Records were reviewed for 174 children undergoing peanut OIT at a pediatric allergy clinic. Patient age, peanut skin prick test results, and peanut-specific immunoglobulin E (sIgE) results, with inclusion of additional foods in OIT, were analyzed for correlations with OIT outcomes., Results: To date, 144 patients have achieved maintenance dosing, 50 of whom transitioned to ad lib twice-weekly peanut ingestion. A total of 30 discontinued OIT. In addition, 47 patients who underwent multifood OIT had no significant difference in reactions (FDR-adjusted P = .48) or time-to-reach maintenance (FDR-adjusted P = .48) compared with those on peanut OIT alone. Age at initiation inversely correlated with achievement of maintenance: 92% of patients 0.5 to less than 5 years, 81% of those 5 to less than 11 years, and 70% of those 11 to less than 18 years reached and continued maintenance (P = .01). Baseline peanut-sIgE level positively correlated with number of reactions during updosing (P < .001) and maintenance (P = .005), though it was not significantly different in patients achieving successful maintenance vs those who discontinued OIT (P = .09). Furthermore, 66% of patients experienced greater than or equal to 1 adverse reaction during OIT. Of those on ad lib peanut ingestion, 2 reported mild reactions after lapses in peanut consumption., Conclusion: Clinical peanut OIT has similar outcomes to research protocols. OIT can be successful in older children and those with high peanut-sIgE levels, though these factors affect outcomes. Clinical and laboratory criteria can guide successful transition to intermittent ad lib peanut consumption., (Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
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