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3. Intensive chemotherapy with or without gemtuzumab ozogamicin in patients with NPM1-mutated acute myeloid leukaemia (AMLSG 09–09): a randomised, open-label, multicentre, phase 3 trial

Author

Döhner, Hartmut, Weber, Daniela, Krzykalla, Julia, Fiedler, Walter, Kühn, Michael W.M., Schroeder, Thomas, Mayer, Karin, Lübbert, Michael, Wattad, Mohammad, Götze, Katharina, Fransecky, Lars, Koller, Elisabeth, Wulf, Gerald, Schleicher, Jan, Ringhoffer, Mark, Greil, Richard, Hertenstein, Bernd, Krauter, Jürgen, Martens, Uwe M., Nachbaur, David, Samra, Maisun Abu, Machherndl-Spandl, Sigrid, Basara, Nadezda, Leis, Claudia, Schrade, Anika, Kapp-Schwoerer, Silke, Cocciardi, Sibylle, Bullinger, Lars, Thol, Felicitas, Heuser, Michael, Paschka, Peter, Gaidzik, Verena I., Saadati, Maral, Benner, Axel, Schlenk, Richard F., Döhner, Konstanze, Ganser, Arnold, Kühn, Michael W M, Wattad, Mohammed, Martens, Uwe M, Gaidzik, Verena I, and Schlenk, Richard F

Published
2023
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4. Measurable residual disease monitoring in AML with FLT3-ITD treated with intensive chemotherapy plus midostaurin

Author

Rücker, Frank G., Bullinger, Lars, Cocciardi, Sibylle, Skambraks, Sabrina, Luck, Tamara J., Weber, Daniela, Krzykalla, Julia, Pozek, Ema, Schneider, Isabelle, Corbacioglu, Andrea, Gaidzik, Verena I., Meid, Annika, Aicher, Sophia, Stegelmann, Frank, Schrade, Anika, Theis, Frauke, Fiedler, Walter, Salih, Helmut R., Wulf, Gerald, Salwender, Hans, Schroeder, Thomas, Götze, Katharina S., Kühn, Michael W. M., Lübbert, Michael, Schlenk, Richard F., Benner, Axel, Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Döhner, Hartmut, and Döhner, Konstanze

Published
2024
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5. Midostaurin plus intensive chemotherapy for younger and older patients with AML and FLT3 internal tandem duplications

Author

Döhner, Hartmut, Weber, Daniela, Krzykalla, Julia, Fiedler, Walter, Wulf, Gerald, Salih, Helmut, Lübbert, Michael, Kühn, Michael W.M., Schroeder, Thomas, Salwender, Hans, Götze, Katharina, Westermann, Jörg, Fransecky, Lars, Mayer, Karin, Hertenstein, Bernd, Ringhoffer, Mark, Tischler, Hans-Joachim, Machherndl-Spandl, Sigrid, Schrade, Anika, Paschka, Peter, Gaidzik, Verena I., Theis, Frauke, Thol, Felicitas, Heuser, Michael, Schlenk, Richard F., Bullinger, Lars, Saadati, Maral, Benner, Axel, Larson, Richard, Stone, Richard, Döhner, Konstanze, and Ganser, Arnold

Published
2022
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6. The association of Health-Related Quality of Life and 1-year-survival in sarcoma patients—results of a Nationwide Observational Study (PROSa)

Author

Eichler, Martin, Singer, Susanne, Hentschel, Leopold, Richter, Stephan, Hohenberger, Peter, Kasper, Bernd, Andreou, Dimosthenis, Pink, Daniel, Jakob, Jens, Grützmann, Robert, Fung, Stephen, Wardelmann, Eva, Arndt, Karin, Heidt, Vitali, Bonilla, Sergio Armando Zapata, Gaidzik, Verena I., Jambor, Helena K., Weitz, Jürgen, Schaser, Klaus-Dieter, Bornhäuser, Martin, Schmitt, Jochen, and Schuler, Markus K.

Published
2022
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7. Desmoplastic Small Round Cell Tumors: Clinical Presentation, Molecular Characterization, and Therapeutic Approach of Seven Patients.

Author

Gaidzik, Verena I., Mayer-Steinacker, Regine, Wittau, Mathias, Schultheiß, Markus, v. Baer, Alexandra, Oehl-Huber, Kathrin, Dahlum, Sonja, Fischer, Anja, Gerstenmaier, Uwe, Seufferlein, Thomas, Buck, Andreas, Beer, Ambros, Thaiss, Wolfgang, Möller, Peter, Döhner, Hartmut, Siebert, Reiner, Marienfeld, Ralf, Barth, Thomas F. E., and Chen, Tom

Subjects
*THERAPEUTIC use of antineoplastic agents, *SARCOMA, *GENOMICS, *RARE diseases, *SYMPTOMS, *DESCRIPTIVE statistics, *CELL cycle, *DECISION making in clinical medicine, *IMMUNOHISTOCHEMISTRY, *GENE expression, *CANCER chemotherapy, *FLUORESCENCE in situ hybridization, *MICROARRAY technology, *MOLECULAR biology, *CASE studies, *STAINS & staining (Microscopy), *SEQUENCE analysis, *DISEASE progression
Abstract

Desmoplastic small round blue cell tumor (DSRCT) is a highly aggressive fatal sarcoma without evidence‐based therapeutic guidelines. We present here seven patients with DSRCT including immunohistochemistry combined with fluorescence in situ hybridization (FISH), next generation sequencing (NGS, n = 6) as well as OncoScan array (n = 3) analyses and show consecutive therapeutic approaches. All seven DSRCT patients presented with an extended abdominal mass; median age at diagnosis was 24.8 years. NGS analyses revealed five class 4 or 5 sequence variants. Remarkably, OncoScan and targeted analyses by FISH identified genomic gains of CCND1 in two cases. Cyclin D1 expression was present in all seven tumors as shown by immunohistochemical staining. Multimodal therapeutic concepts included systemic therapies, resection, and radiation. Six patients were treated as first‐line therapy with conventional chemotherapy. All except one patient had a dismal therapy response. Subsequent therapy lines consisted of chemotherapeutic combinations followed by targeted therapies. Due to Cyclin D1 expression, the CDK4/6 inhibitor palbociclib was applied to four patients. The median therapy duration until disease progression in these patients was 4.5 months (range, 1.5–5 months). So, CCND1 genomic gain and Cyclin D1 expression are common features pointing to cell‐cycle deregulation as a possible therapeutic target. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Posttransplantation MRD monitoring in patients with AML by next-generation sequencing using DTA and non-DTA mutations

Author

Heuser, Michael, Heida, Bennet, Büttner, Konstantin, Wienecke, Clara Philine, Teich, Katrin, Funke, Carolin, Brandes, Maximilian, Klement, Piroska, Liebich, Alessandro, Wichmann, Martin, Neziri, Blerina, Chaturvedi, Anuhar, Kloos, Arnold, Mintzas, Konstantinos, Gaidzik, Verena I., Paschka, Peter, Bullinger, Lars, Fiedler, Walter, Heim, Albert, Puppe, Wolfram, Krauter, Jürgen, Döhner, Konstanze, Döhner, Hartmut, Ganser, Arnold, Stadler, Michael, Hambach, Lothar, Gabdoulline, Razif, and Thol, Felicitas

Published
2021
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9. Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1-mutated AML: results from the AMLSG 09-09 trial

Author

Kapp-Schwoerer, Silke, Weber, Daniela, Corbacioglu, Andrea, Gaidzik, Verena I., Paschka, Peter, Krönke, Jan, Theis, Frauke, Rücker, Frank G., Teleanu, Maria-Veronica, Panina, Ekaterina, Jahn, Nikolaus, Herzig, Julia, Kubanek, Lena, Schrade, Anika, Göhring, Gudrun, Fiedler, Walter, Kindler, Thomas, Schroeder, Thomas, Mayer, Karin T., Lübbert, Michael, Wattad, Mohammed, Götze, Katharina S., Horst, Heinz A., Koller, Elisabeth, Wulf, Gerald, Schleicher, Jan, Bentz, Martin, Krauter, Jürgen, Bullinger, Lars, Krzykalla, Julia, Benner, Axel, Schlenk, Richard F., Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Döhner, Hartmut, and Döhner, Konstanze

Published
2020
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10. Genomic heterogeneity in core-binding factor acute myeloid leukemia and its clinical implication

Author

Jahn, Nikolaus, Terzer, Tobias, Sträng, Eric, Dolnik, Anna, Cocciardi, Sibylle, Panina, Ekaterina, Corbacioglu, Andrea, Herzig, Julia, Weber, Daniela, Schrade, Anika, Götze, Katharina, Schröder, Thomas, Lübbert, Michael, Wellnitz, Dominique, Koller, Elisabeth, Schlenk, Richard F., Gaidzik, Verena I., Paschka, Peter, Rücker, Frank G., Heuser, Michael, Thol, Felicitas, Ganser, Arnold, Benner, Axel, Döhner, Hartmut, Bullinger, Lars, and Döhner, Konstanze

Published
2020
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11. Refinement of the prognostic impact of somatic CEBPA bZIP domain mutations in acute myeloid leukemia: Results of the AML Study Group (AMLSG).

Author

Rücker, Frank G., Corbacioglu, Andrea, Krzykalla, Julia, Cocciardi, Sibylle, Lengerke, Claudia, Germing, Ulrich, Wulf, Gerald, Samra, Maisun A., Teichmann, Lino L., Lübbert, Michael, Kühn, Michael W. M., Bentz, Martin, Westermann, Jörg, Bullinger, Lars, Gaidzik, Verena I., Meid, Annika, Aicher, Sophia, Stegelmann, Frank, Weber, Daniela, and Schrade, Anika

Published
2024
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12. Geriatric Assessment of Older Patients Receiving Trabectedin in First-Line Treatment for Advanced Soft Tissue Sarcomas: The E-TRAB Study from The German Interdisciplinary Sarcoma Group (GISG-13)

Author

Kasper, Bernd, primary, Pink, Daniel, additional, Rothermundt, Christian, additional, Richter, Stephan, additional, Augustin, Marinela, additional, Kollar, Attila, additional, Kunitz, Annegret, additional, Eisterer, Wolfgang, additional, Gaidzik, Verena, additional, Brodowicz, Thomas, additional, Egerer, Gerlinde, additional, Reichardt, Peter, additional, Hohenberger, Peter, additional, and Schuler, Markus K., additional

Published
2024
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13. Functional and clinical characterization of the alternatively spliced isoform AML1-ETO9a in adult patients with translocation t(8;21)(q22;q22.1) acute myeloid leukemia (AML)

Author

Agrawal, Mridul, Schwarz, Peggy, Giaimo, Benedetto Daniele, Bedzhov, Ivan, Corbacioglu, Andrea, Weber, Daniela, Gaidzik, Verena I., Jahn, Nikolaus, Rücker, Frank G., Schroeder, Thomas, Kindler, Thomas, Wattad, Mohammed, Götze, Katharina, Lübbert, Michael, Salwender, Hans, Ringhoffer, Mark, Lange, Elisabeth, Koller, Elisabeth, Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Bullinger, Lars, Paschka, Peter, Döhner, Hartmut, Geiger, Hartmut, Borggrefe, Tilman, Döhner, Konstanze, and Oswald, Franz

Published
2020
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15. Real-world experience of CPX-351 as first-line treatment for patients with acute myeloid leukemia

Author

Rautenberg, Christina, Stölzel, Friedrich, Röllig, Christoph, Stelljes, Matthias, Gaidzik, Verena, Lauseker, Michael, Kriege, Oliver, Verbeek, Mareike, Unglaub, Julia Marie, Thol, Felicitas, Krause, Stefan W., Hänel, Mathias, Neuerburg, Charlotte, Vucinic, Vladan, Jehn, Christian-Friedrich, Severmann, Julia, Wass, Maxi, Fransecky, Lars, Chemnitz, Jens, Holtick, Udo, Schäfer-Eckart, Kerstin, Schröder, Josephine, Kraus, Sabrina, Krüger, William, Kaiser, Ulrich, Scholl, Sebastian, Koch, Kathrin, Henning, Lea, Kobbe, Guido, Haas, Rainer, Alakel, Nael, Röhnert, Maximilian-Alexander, Sockel, Katja, Hanoun, Maher, Platzbecker, Uwe, Holderried, Tobias A. W., Morgner, Anke, Heuser, Michael, Sauer, Tim, Götze, Katharina S., Wagner-Drouet, Eva, Döhner, Konstanze, Döhner, Hartmut, Schliemann, Christoph, Schetelig, Johannes, Bornhäuser, Martin, Germing, Ulrich, Schroeder, Thomas, and Middeke, Jan Moritz

Published
2021
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16. Measurable residual disease monitoring in acute myeloid leukemia with t(8;21)(q22;q22.1): results from the AML Study Group

Author

Rücker, Frank G., Agrawal, Mridul, Corbacioglu, Andrea, Weber, Daniela, Kapp-Schwoerer, Silke, Gaidzik, Verena I., Jahn, Nikolaus, Schroeder, Thomas, Wattad, Mohammed, Lübbert, Michael, Koller, Elisabeth, Kindler, Thomas, Götze, Katharina, Ringhoffer, Mark, Westermann, Jörg, Fiedler, Walter, Horst, Heinz A., Greil, Richard, Schroers, Roland, Mayer, Karin, Heinicke, Thomas, Krauter, Jürgen, Schlenk, Richard F., Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Bullinger, Lars, Paschka, Peter, Döhner, Hartmut, and Döhner, Konstanze

Published
2019
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17. Midostaurin added to chemotherapy and continued single-agent maintenance therapy in acute myeloid leukemia with FLT3-ITD

Author

Schlenk, Richard F., Weber, Daniela, Fiedler, Walter, Salih, Helmut R., Wulf, Gerald, Salwender, Hans, Schroeder, Thomas, Kindler, Thomas, Lübbert, Michael, Wolf, Dominik, Westermann, Jörg, Kraemer, Doris, Götze, Katharina S., Horst, Heinz-August, Krauter, Jürgen, Girschikofsky, Michael, Ringhoffer, Mark, Südhoff, Thomas, Held, Gerhard, Derigs, Hans-Günter, Schroers, Roland, Greil, Richard, Grießhammer, Martin, Lange, Elisabeth, Burchardt, Alexander, Martens, Uwe, Hertenstein, Bernd, Marretta, Lore, Heuser, Michael, Thol, Felicitas, Gaidzik, Verena I., Herr, Wolfgang, Krzykalla, Julia, Benner, Axel, Döhner, Konstanze, Ganser, Arnold, Paschka, Peter, and Döhner, Hartmut

Published
2019
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19. Measurable residual disease monitoring by NGS before allogeneic hematopoietic cell transplantation in AML

Author

Thol, Felicitas, Gabdoulline, Razif, Liebich, Alessandro, Klement, Piroska, Schiller, Johannes, Kandziora, Christian, Hambach, Lothar, Stadler, Michael, Koenecke, Christian, Flintrop, Madita, Pankratz, Mira, Wichmann, Martin, Neziri, Blerina, Büttner, Konstantin, Heida, Bennet, Klesse, Sabrina, Chaturvedi, Anuhar, Kloos, Arnold, Göhring, Gudrun, Schlegelberger, Brigitte, Gaidzik, Verena I., Bullinger, Lars, Fiedler, Walter, Heim, Albert, Hamwi, Iyas, Eder, Matthias, Krauter, Jürgen, Schlenk, Richard F., Paschka, Peter, Döhner, Konstanze, Döhner, Hartmut, Ganser, Arnold, and Heuser, Michael

Published
2018
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20. S135: NEXT-GENERATION SEQUENCING-BASED MEASURABLE RESIDUAL DISEASE MONITORING IN ACUTE MYELOID LEUKEMIA WITH FLT3 INTERNAL TANDEM DUPLICATION TREATED WITH INTENSIVE CHEMOTHERAPY PLUS MIDOSTAURIN

Author

Rücker, Frank G, primary, Bullinger, Lars, additional, Cocciardi, Sibylle, additional, Skambraks, Sabrina, additional, Luck, Tamara J, additional, Weber, Daniela, additional, Schneider, Isabelle, additional, Corbacioglu, Andrea, additional, Gaidzik, Verena I, additional, Jahn, Ekaterina, additional, Jahn, Nikolaus, additional, Kapp-Schwoerer, Silke, additional, Schrade, Anika, additional, Theis, Frauke, additional, Fiedler, Walter, additional, Salih, Helmut R, additional, Wulf, Gerald, additional, Salwender, Hans, additional, Schroeder, Thomas, additional, Götze, Katharina S, additional, Kindler, Thomas, additional, Lübbert, Michael, additional, Schlenk, Richard F, additional, Thol, Felicitas, additional, Heuser, Michael, additional, Ganser, Arnold, additional, Döhner, Hartmut, additional, and Döhner, Konstanze, additional

Published
2023
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24. Adding dasatinib to intensive treatment in core-binding factor acute myeloid leukemia—results of the AMLSG 11-08 trial

Author

Paschka, Peter, Schlenk, Richard F, Weber, Daniela, Benner, Axel, Bullinger, Lars, Heuser, Michael, Gaidzik, Verena I, Thol, Felicitas, Agrawal, Mridul, Teleanu, Veronica, Lübbert, Michael, Fiedler, Walter, Radsak, Markus, Krauter, Jürgen, Horst, Heinz-A., Greil, Richard, Mayer, Karin, Kündgen, Andrea, Martens, Uwe, Heil, Gerhard, Salih, Helmut R, Hertenstein, Bernd, Schwänen, Carsten, Wulf, Gerald, Lange, Elisabeth, Pfreundschuh, Michael, Ringhoffer, Mark, Girschikofsky, Michael, Heinicke, Thomas, Kraemer, Doris, Göhring, Gudrun, Ganser, Arnold, Döhner, Konstanze, and Döhner, Hartmut

Published
2018
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25. Palbociclib in Acute Leukemias With KMT2A-rearrangement: Results of AMLSG 23-14 Trial

Author

Gaidzik, Verena I., primary, Paschka, Peter, additional, Schlenk, Richard F., additional, Weber, Daniela, additional, Fröhling, Stefan, additional, Krämer, Alwin, additional, Wäsch, Ralph, additional, Westermann, Jörg, additional, Mayer, Karin, additional, de Wit, Maike, additional, Fiedler, Walter, additional, Benner, Axel, additional, Heuser, Michael, additional, Thol, Felicitas, additional, Döhner, Konstanze, additional, Ganser, Arnold, additional, and Döhner, Hartmut, additional

Published
2023
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26. Supplementary Figures from Selective BCL-2 Inhibition by ABT-199 Causes On-Target Cell Death in Acute Myeloid Leukemia

Author

Pan, Rongqing, primary, Hogdal, Leah J., primary, Benito, Juliana M., primary, Bucci, Donna, primary, Han, Lina, primary, Borthakur, Gautam, primary, Cortes, Jorge, primary, DeAngelo, Daniel J., primary, Debose, LaKeisha, primary, Mu, Hong, primary, Döhner, Hartmut, primary, Gaidzik, Verena I., primary, Galinsky, Ilene, primary, Golfman, Leonard S., primary, Haferlach, Torsten, primary, Harutyunyan, Karine G., primary, Hu, Jianhua, primary, Leverson, Joel D., primary, Marcucci, Guido, primary, Müschen, Markus, primary, Newman, Rachel, primary, Park, Eugene, primary, Ruvolo, Peter P., primary, Ruvolo, Vivian, primary, Ryan, Jeremy, primary, Schindela, Sonja, primary, Zweidler-McKay, Patrick, primary, Stone, Richard M., primary, Kantarjian, Hagop, primary, Andreeff, Michael, primary, Konopleva, Marina, primary, and Letai, Anthony G., primary

Published
2023
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27. Data from Selective BCL-2 Inhibition by ABT-199 Causes On-Target Cell Death in Acute Myeloid Leukemia

Author

Pan, Rongqing, primary, Hogdal, Leah J., primary, Benito, Juliana M., primary, Bucci, Donna, primary, Han, Lina, primary, Borthakur, Gautam, primary, Cortes, Jorge, primary, DeAngelo, Daniel J., primary, Debose, LaKeisha, primary, Mu, Hong, primary, Döhner, Hartmut, primary, Gaidzik, Verena I., primary, Galinsky, Ilene, primary, Golfman, Leonard S., primary, Haferlach, Torsten, primary, Harutyunyan, Karine G., primary, Hu, Jianhua, primary, Leverson, Joel D., primary, Marcucci, Guido, primary, Müschen, Markus, primary, Newman, Rachel, primary, Park, Eugene, primary, Ruvolo, Peter P., primary, Ruvolo, Vivian, primary, Ryan, Jeremy, primary, Schindela, Sonja, primary, Zweidler-McKay, Patrick, primary, Stone, Richard M., primary, Kantarjian, Hagop, primary, Andreeff, Michael, primary, Konopleva, Marina, primary, and Letai, Anthony G., primary

Published
2023
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28. Supplementary Table 2 from Selective BCL-2 Inhibition by ABT-199 Causes On-Target Cell Death in Acute Myeloid Leukemia

Author

Pan, Rongqing, primary, Hogdal, Leah J., primary, Benito, Juliana M., primary, Bucci, Donna, primary, Han, Lina, primary, Borthakur, Gautam, primary, Cortes, Jorge, primary, DeAngelo, Daniel J., primary, Debose, LaKeisha, primary, Mu, Hong, primary, Döhner, Hartmut, primary, Gaidzik, Verena I., primary, Galinsky, Ilene, primary, Golfman, Leonard S., primary, Haferlach, Torsten, primary, Harutyunyan, Karine G., primary, Hu, Jianhua, primary, Leverson, Joel D., primary, Marcucci, Guido, primary, Müschen, Markus, primary, Newman, Rachel, primary, Park, Eugene, primary, Ruvolo, Peter P., primary, Ruvolo, Vivian, primary, Ryan, Jeremy, primary, Schindela, Sonja, primary, Zweidler-McKay, Patrick, primary, Stone, Richard M., primary, Kantarjian, Hagop, primary, Andreeff, Michael, primary, Konopleva, Marina, primary, and Letai, Anthony G., primary

Published
2023
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29. Supplementary Methods from Selective BCL-2 Inhibition by ABT-199 Causes On-Target Cell Death in Acute Myeloid Leukemia

Author

Pan, Rongqing, primary, Hogdal, Leah J., primary, Benito, Juliana M., primary, Bucci, Donna, primary, Han, Lina, primary, Borthakur, Gautam, primary, Cortes, Jorge, primary, DeAngelo, Daniel J., primary, Debose, LaKeisha, primary, Mu, Hong, primary, Döhner, Hartmut, primary, Gaidzik, Verena I., primary, Galinsky, Ilene, primary, Golfman, Leonard S., primary, Haferlach, Torsten, primary, Harutyunyan, Karine G., primary, Hu, Jianhua, primary, Leverson, Joel D., primary, Marcucci, Guido, primary, Müschen, Markus, primary, Newman, Rachel, primary, Park, Eugene, primary, Ruvolo, Peter P., primary, Ruvolo, Vivian, primary, Ryan, Jeremy, primary, Schindela, Sonja, primary, Zweidler-McKay, Patrick, primary, Stone, Richard M., primary, Kantarjian, Hagop, primary, Andreeff, Michael, primary, Konopleva, Marina, primary, and Letai, Anthony G., primary

Published
2023
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30. Supplementary Figure Legends from Selective BCL-2 Inhibition by ABT-199 Causes On-Target Cell Death in Acute Myeloid Leukemia

Author

Pan, Rongqing, primary, Hogdal, Leah J., primary, Benito, Juliana M., primary, Bucci, Donna, primary, Han, Lina, primary, Borthakur, Gautam, primary, Cortes, Jorge, primary, DeAngelo, Daniel J., primary, Debose, LaKeisha, primary, Mu, Hong, primary, Döhner, Hartmut, primary, Gaidzik, Verena I., primary, Galinsky, Ilene, primary, Golfman, Leonard S., primary, Haferlach, Torsten, primary, Harutyunyan, Karine G., primary, Hu, Jianhua, primary, Leverson, Joel D., primary, Marcucci, Guido, primary, Müschen, Markus, primary, Newman, Rachel, primary, Park, Eugene, primary, Ruvolo, Peter P., primary, Ruvolo, Vivian, primary, Ryan, Jeremy, primary, Schindela, Sonja, primary, Zweidler-McKay, Patrick, primary, Stone, Richard M., primary, Kantarjian, Hagop, primary, Andreeff, Michael, primary, Konopleva, Marina, primary, and Letai, Anthony G., primary

Published
2023
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31. Supplementary Table 1 from Selective BCL-2 Inhibition by ABT-199 Causes On-Target Cell Death in Acute Myeloid Leukemia

Author

Pan, Rongqing, primary, Hogdal, Leah J., primary, Benito, Juliana M., primary, Bucci, Donna, primary, Han, Lina, primary, Borthakur, Gautam, primary, Cortes, Jorge, primary, DeAngelo, Daniel J., primary, Debose, LaKeisha, primary, Mu, Hong, primary, Döhner, Hartmut, primary, Gaidzik, Verena I., primary, Galinsky, Ilene, primary, Golfman, Leonard S., primary, Haferlach, Torsten, primary, Harutyunyan, Karine G., primary, Hu, Jianhua, primary, Leverson, Joel D., primary, Marcucci, Guido, primary, Müschen, Markus, primary, Newman, Rachel, primary, Park, Eugene, primary, Ruvolo, Peter P., primary, Ruvolo, Vivian, primary, Ryan, Jeremy, primary, Schindela, Sonja, primary, Zweidler-McKay, Patrick, primary, Stone, Richard M., primary, Kantarjian, Hagop, primary, Andreeff, Michael, primary, Konopleva, Marina, primary, and Letai, Anthony G., primary

Published
2023
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32. A Lack of Diversity, Equity, and Inclusion in Clinical Research Has Direct Impact on Patient Care

Author

El-Galaly, Tarec Christoffer, Gaidzik, Verena I., Gaman, Mihnea Alexandru, Antic, Darko, Okosun, Jessica, Copland, Mhairi, Sexl, Veronika, Fielding, Adele K., Doeswijk, Robin, Parker, Helen, Dreyling, Martin, Döhner, Konstanze, Almeida, António Medina, Macintyre, Elizabeth, Gribben, John G., Grønbæk, Kirsten, El-Galaly, Tarec Christoffer, Gaidzik, Verena I., Gaman, Mihnea Alexandru, Antic, Darko, Okosun, Jessica, Copland, Mhairi, Sexl, Veronika, Fielding, Adele K., Doeswijk, Robin, Parker, Helen, Dreyling, Martin, Döhner, Konstanze, Almeida, António Medina, Macintyre, Elizabeth, Gribben, John G., and Grønbæk, Kirsten

Abstract

Diversity, equity, and inclusion (DEI) in research is important. This is the case not only because it is simply the right thing to do but also because DEI fosters collaboration, empathy, and psychological safety between scientists and clinicians as well as in our attitudes to and relations with patients. Inclusion of patient samples from diverse populations is critical to ensure that the full range of biological variabilities are represented in basic and clinical research.

Published
2023

33. Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation

Author

Cocciardi, Sibylle, Dolnik, Anna, Kapp-Schwoerer, Silke, Rücker, Frank G., Lux, Susanne, Blätte, Tamara J., Skambraks, Sabrina, Krönke, Jan, Heidel, Florian H., Schnöder, Tina M., Corbacioglu, Andrea, Gaidzik, Verena I., Paschka, Peter, Teleanu, Veronica, Göhring, Gudrun, Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Weber, Daniela, Sträng, Eric, Kestler, Hans A., Döhner, Hartmut, Bullinger, Lars, and Döhner, Konstanze

Published
2019
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36. All-trans retinoic acid as adjunct to intensive treatment in younger adult patients with acute myeloid leukemia: results of the randomized AMLSG 07-04 study

Author

Schlenk, Richard F., Lübbert, Michael, Benner, Axel, Lamparter, Alexander, Krauter, Jürgen, Herr, Wolfgang, Martin, Hans, Salih, Helmut R., Kündgen, Andrea, Horst, Heinz-A., Brossart, Peter, Götze, Katharina, Nachbaur, David, Wattad, Mohammed, Köhne, Claus-Henning, Fiedler, Walter, Bentz, Martin, Wulf, Gerald, Held, Gerhard, Hertenstein, Bernd, Salwender, Hans, Gaidzik, Verena I, Schlegelberger, Brigitte, Weber, Daniela, Döhner, Konstanze, Ganser, Arnold, Döhner, Hartmut, and for the German-Austrian Acute Myeloid Leukemia Study Group

Published
2016
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37. Prognostic Impact of Clonal Hierarchy of Myelodysplasia-Related Gene Mutations in AML Patients

Author

Mecklenbrauck, Rabea, primary, Borchert, Nora, additional, Funke, Carolin, additional, Brandes, Maximilian, additional, Dallmann, Louisa-Kristin, additional, Klement, Piroska, additional, Fiedler, Walter, additional, Krauter, Jürgen, additional, Trummer, Arne, additional, Hertenstein, Bernd, additional, Voss, Andreas, additional, Lübbert, Michael, additional, Gaidzik, Verena I., additional, Döhner, Konstanze, additional, Döhner, Hartmut, additional, Ganser, Arnold, additional, Thol, Felicitas R., additional, and Heuser, Michael, additional

Published
2022
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38. Gemtuzumab Ozogamicin Plus Intensive Chemotherapy for Patients with NPM1-Mutated Acute Myeloid Leukemia

Author

Döhner, Hartmut, primary, Weber, Daniela, additional, Krzykalla, Julia, additional, Fiedler, Walter, additional, Kühn, Michael W.M., additional, Schroeder, Thomas, additional, Mayer, Karin, additional, Lübbert, Michael, additional, Wattad, Mohammad, additional, Götze, Katharina, additional, Fransecky, Lars, additional, Koller, Elisabeth, additional, Wulf, Gerald, additional, Schleicher, Jan, additional, Ringhoffer, Mark, additional, Greil, Richard, additional, Hertenstein, Bernd, additional, Krauter, Jürgen, additional, Martens, Uwe M., additional, Nachbaur, David, additional, Samra, Maisun Abu, additional, Machherndl-Spandl, Sigrid, additional, Basara, Nadezda, additional, Leis, Claudia, additional, Schrade, Anika, additional, Kapp-Schwoerer, Silke, additional, Bullinger, Lars, additional, Thol, Felicitas R., additional, Heuser, Michael, additional, Paschka, Peter, additional, Gaidzik, Verena I., additional, Saadati, Maral, additional, Benner, Axel, additional, Schlenk, Richard F., additional, Döhner, Konstanze, additional, and Ganser, Arnold, additional

Published
2022
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39. Poster: AML-440 Prognosis of Molecularly-Defined Secondary Acute Myeloid Leukemia Patients

Author

Mecklenbrauck, Rabea, primary, Borchert, Nora, additional, Klement, Piroska, additional, Funke, Carolin, additional, Brandes, Maximilian, additional, Dallmann, Louisa-Kristin, additional, Fiedler, Walter, additional, Krauter, Jürgen, additional, Trummer, Arne, additional, Hertenstein, Bernd, additional, Voß, Andreas, additional, Lübbert, Michael, additional, Gaidzik, Verena, additional, Döhner, Konstanze, additional, Döhner, Hartmut, additional, Ganser, Arnold, additional, Thol, Felicitas, additional, and Heuser, Michael, additional

Published
2022
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40. Trailblazing precision medicine in Europe: A joint view by Genomic Medicine Sweden and the Centers for Personalized Medicine, ZPM, in Germany

Author

Stenzinger, Albrecht, primary, Edsjö, Anders, additional, Ploeger, Carolin, additional, Friedman, Mikaela, additional, Fröhling, Stefan, additional, Wirta, Valtteri, additional, Seufferlein, Thomas, additional, Botling, Johan, additional, Duyster, Justus, additional, Akhras, Michael, additional, Thimme, Robert, additional, Fioretos, Thoas, additional, Bitzer, Michael, additional, Cavelier, Lucia, additional, Schirmacher, Peter, additional, Malek, Nisar, additional, Rosenquist, Richard, additional, Lindstrand, Anna, additional, Wedell, Anna, additional, Gisselsson, David, additional, Melén, Erik, additional, Helenius, Gisela, additional, Ehrencrona, Hans, additional, Engstrand, Lars, additional, Palmqvist, Lars, additional, Levin, Lars-Åke, additional, Lovmar, Lovisa, additional, Landström, Maréne, additional, Hallbeck, Martin, additional, Wadelius, Mia, additional, Sikora, Per, additional, Beer, Ambros J., additional, Illert, Anna L., additional, Budczies, Jan, additional, Nikolaou, Konstantin, additional, Kohlbacher, Oliver, additional, Horak, Peter, additional, Kuhn, Peter, additional, Schroeder, Christopher, additional, Boerries, Melanie, additional, Lassmann, Silke, additional, and Gaidzik, Verena I., additional

Published
2022
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41. Differential impact of allelic ratio and insertion site in FLT3-ITD–positive AML with respect to allogeneic transplantation

Author

Schlenk, Richard F., Kayser, Sabine, Bullinger, Lars, Kobbe, Guido, Casper, Jochen, Ringhoffer, Mark, Held, Gerhard, Brossart, Peter, Lübbert, Michael, Salih, Helmut R., Kindler, Thomas, Horst, Heinz A., Wulf, Gerald, Nachbaur, David, Götze, Katharina, Lamparter, Alexander, Paschka, Peter, Gaidzik, Verena I., Teleanu, Veronica, Späth, Daniela, Benner, Axel, Krauter, Jürgen, Ganser, Arnold, Döhner, Hartmut, and Döhner, Konstanze

Published
2014
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42. Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia

Author

Krönke, Jan, Bullinger, Lars, Teleanu, Veronica, Tschürtz, Florian, Gaidzik, Verena I., Kühn, Michael W.M., Rücker, Frank G., Holzmann, Karlheinz, Paschka, Peter, Kapp-Schwörer, Silke, Späth, Daniela, Kindler, Thomas, Schittenhelm, Marcus, Krauter, Jürgen, Ganser, Arnold, Göhring, Gudrun, Schlegelberger, Brigitte, Schlenk, Richard F., Döhner, Hartmut, and Döhner, Konstanze

Published
2013
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43. Clinical impact of DNMT3A mutations in younger adult patients with acute myeloid leukemia: results of the AML Study Group (AMLSG)

Author

Gaidzik, Verena I., Schlenk, Richard F., Paschka, Peter, Stölzle, Anja, Späth, Daniela, Kuendgen, Andrea, von Lilienfeld-Toal, Marie, Brugger, Wolfram, Derigs, Hans Günter, Kremers, Stephan, Greil, Richard, Raghavachar, Aruna, Ringhoffer, Mark, Salih, Helmut R., Wattad, Mohammed, Kirchen, Heinz G., Runde, Volker, Heil, Gerhard, Petzer, Andreas L., Girschikofsky, Michael, Heuser, Michael, Kayser, Sabine, Goehring, Gudrun, Teleanu, Maria-Veronica, Schlegelberger, Brigitte, Ganser, Arnold, Krauter, Jürgen, Bullinger, Lars, Döhner, Hartmut, and Döhner, Konstanze

Published
2013
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44. Secondary genetic lesions in acute myeloid leukemia with inv(16) or t(16;16): a study of the German-Austrian AML Study Group (AMLSG)

Author

Paschka, Peter, Du, Juan, Schlenk, Richard F., Gaidzik, Verena I., Bullinger, Lars, Corbacioglu, Andrea, Späth, Daniela, Kayser, Sabine, Schlegelberger, Brigitte, Krauter, Jürgen, Ganser, Arnold, Köhne, Claus-Henning, Held, Gerhard, von Lilienfeld-Toal, Marie, Kirchen, Heinz, Rummel, Mathias, Götze, Katharina, Horst, Heinz-August, Ringhoffer, Mark, Lübbert, Michael, Wattad, Mohammed, Salih, Helmut R., Kündgen, Andrea, Döhner, Hartmut, and Döhner, Konstanze

Published
2013
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45. Conceptual framework for precision cancer medicine in Germany: Consensus statement of the Deutsche Krebshilfe working group 'Molecular Diagnostics and Therapy (vol 135, pg 1, 2020)

Author

Westphalen, C. Benedikt, Bokemeyer, Carsten, Buettner, Reinhard, Froehling, Stefan, Gaidzik, Verena I., Glimm, Hanno, Hacker, Ulrich T., Heinemann, Volker, Illert, Anna L., Keilholz, Ulrich, Kindler, Thomas, Kirschner, Martin, Schilling, Bastian, Siveke, Jens T., Schroeder, Thomas, Tischler, Verena, Wagner, Sebastian, Weichert, Wilko, Zips, Daniel, Loges, Sonja, Westphalen, C. Benedikt, Bokemeyer, Carsten, Buettner, Reinhard, Froehling, Stefan, Gaidzik, Verena I., Glimm, Hanno, Hacker, Ulrich T., Heinemann, Volker, Illert, Anna L., Keilholz, Ulrich, Kindler, Thomas, Kirschner, Martin, Schilling, Bastian, Siveke, Jens T., Schroeder, Thomas, Tischler, Verena, Wagner, Sebastian, Weichert, Wilko, Zips, Daniel, and Loges, Sonja

Published
2022

46. Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin remodeling and splicing

Author

Dolnik, Anna, Engelmann, Julia C., Scharfenberger-Schmeer, Maren, Mauch, Julian, Kelkenberg-Schade, Sabine, Haldemann, Berit, Fries, Tamara, Krönke, Jan, Kühn, Michael W.M., Paschka, Peter, Kayser, Sabine, Wolf, Stephan, Gaidzik, Verena I., Schlenk, Richard F., Rücker, Frank G., Döhner, Hartmut, Lottaz, Claudio, Döhner, Konstanze, and Bullinger, Lars

Published
2012
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47. High-resolution genomic profiling of adult and pediatric core-binding factor acute myeloid leukemia reveals new recurrent genomic alterations

Author

Kühn, Michael W.M., Radtke, Ina, Bullinger, Lars, Goorha, Salil, Cheng, Jinjun, Edelmann, Jennifer, Gohlke, Juliane, Su, Xiaoping, Paschka, Peter, Pounds, Stanley, Krauter, Jürgen, Ganser, Arnold, Quessar, Asmaa, Ribeiro, Raul, Gaidzik, Verena I., Shurtleff, Sheila, Krönke, Jan, Holzmann, Karlheinz, Ma, Jing, Schlenk, Richard F., Rubnitz, Jeffrey E., Döhner, Konstanze, Döhner, Hartmut, and Downing, James R.

Published
2012
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48. TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome

Author

Rücker, Frank G., Schlenk, Richard F., Bullinger, Lars, Kayser, Sabine, Teleanu, Veronica, Kett, Helena, Habdank, Marianne, Kugler, Carla-Maria, Holzmann, Karlheinz, Gaidzik, Verena I., Paschka, Peter, Held, Gerhard, von Lilienfeld-Toal, Marie, Lübbert, Michael, Fröhling, Stefan, Zenz, Thorsten, Krauter, Jürgen, Schlegelberger, Brigitte, Ganser, Arnold, Lichter, Peter, Döhner, Konstanze, and Döhner, Hartmut

Published
2012
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49. Corrigendum to 'Conceptual framework for precision cancer medicine in Germany: Consensus statement of the Deutsche Krebshilfe working group Molecular Diagnostics and Therapy'

Author

Westphalen, C. Benedikt, Bokemeyer, Carsten, Büttner, Reinhard, Fröhling, Stefan, Gaidzik, Verena I., Glimm, Hanno, Hacker, Ulrich T., Heinemann, Volker, Illert, Anna L., Keilholz, Ulrich, Kindler, Thomas, Kirschner, Martin, Schilling, Bastian, Siveke, Jens, Schroeder, Thomas, Tischler, Verena, Wagner, Sebastian, Weichert, Wilko, Zips, Daniel, Loges, Sonja, Schadendorf, Dirk, and Schildhaus, Hans-Ulrich

Subjects
Medizin
Abstract

Korrektur zu 10.1016/j.ejca.2020.04.019

Published
2022

50. Corrigendum to “Conceptual framework for precision cancer medicine in Germany: Consensus statement of the Deutsche Krebshilfe working group ‘Molecular Diagnostics and Therapy’” [European Journal of Cancer 135 (2020) 1-7]

Author

Benedikt Westphalen, C., primary, Bokemeyer, Carsten, additional, Büttner, Reinhard, additional, Fröhling, Stefan, additional, Gaidzik, Verena I., additional, Glimm, Hanno, additional, Hacker, Ulrich T., additional, Heinemann, Volker, additional, Illert, Anna L., additional, Keilholz, Ulrich, additional, Kindler, Thomas, additional, Kirschner, Martin, additional, Schilling, Bastian, additional, Siveke, Jens T., additional, Schroeder, Thomas, additional, Tischler, Verena, additional, Wagner, Sebastian, additional, Weichert, Wilko, additional, Zips, Daniel, additional, Loges, Sonja, additional, Bargou (Würzburg), Ralf, additional, Bläker (Leipzig), Hendrik, additional, Börries (Freiburg), Melanie, additional, Brandts (Frankfurt), Christian, additional, von Bubnoff (Freiburg), Nikolas, additional, Demes (Frankfurt), Melanie, additional, Desuki (Mainz), Alexander, additional, Döhner (Ulm), Hartmut, additional, Duyster (Freiburg), Justus, additional, Gaisa (Aachen), Nadine, additional, Heine (Bonn), Annkristin, additional, Heining (Dresden), Christoph, additional, Horak (Heidelberg), Peter, additional, Jelas (Berlin), Ivan, additional, Jost (München), Philipp J., additional, Jung (München), Andreas, additional, Kirchner (München), Thomas, additional, Klauschen (Berlin), Frederick, additional, Kreutzfeldt (Heidelberg), Simon, additional, Kumbrink (München), Jörg, additional, Kunzmann (Würzburg), Volker, additional, Lassmann (Freiburg), Silke, additional, Metzeler (München), Klaus, additional, Möller (Ulm), Peter, additional, Ortiz-Brüchle (Aachen), Nadina, additional, Paret (Mainz), Claudia, additional, Pelusi (Bonn), Natalie, additional, Peters (Freiburg), Christoph, additional, Pfarr (München), Nicole, additional, Richter (Dresden), Daniela, additional, Riedmann (München), Kristina, additional, Rieke (Berlin), Damian, additional, Ritzel (Mainz), Christoph, additional, Schadendorf (Essen), Dirk, additional, Schildhaus (Essen), Hans-Ulrich, additional, Schorle (Bonn), Hubert, additional, Seufferlein (Ulm), Thomas, additional, Simon (Hamburg), Ronald, additional, Stenzinger (Heidelberg), Albrecht, additional, Tabatabai (Tübingen), Ghazaleh, additional, Velthaus (Hamburg), Janna-Lisa, additional, Werner (Freiburg), Martin, additional, Wild (Frankfurt), Peter J., additional, and Wolf (Köln), Jürgen, additional

Published
2022
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