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170 results on '"Gallagher I"'

2. Spectral asymptotics for large skew-symmetric perturbations of the harmonic oscillator

Author

Gallagher, I., Gallay, Th., and Nier, F.

Subjects
Mathematics - Spectral Theory, Mathematics - Analysis of PDEs, 35P15, 35P20, 35P99
Abstract

Originally motivated by a stability problem in Fluid Mechanics, we study the spectral and pseudospectral properties of the differential operator $H_\epsilon = -\partial_x^2 + x^2 + i\epsilon^{-1}f(x)$ on $L^2(R)$, where $f$ is a real-valued function and $\epsilon > 0$ a small parameter. We define $\Sigma(\epsilon)$ as the infimum of the real part of the spectrum of $H_\epsilon$, and $\Psi(\epsilon)^{-1}$ as the supremum of the norm of the resolvent of $H_\epsilon$ along the imaginary axis. Under appropriate conditions on $f$, we show that both quantities $\Sigma(\epsilon)$, $\Psi(\epsilon)$ go to infinity as $\epsilon \to 0$, and we give precise estimates of the growth rate of $\Psi(\epsilon)$. We also provide an example where $\Sigma(\epsilon)$ is much larger than $\Psi(\epsilon)$ if $\epsilon$ is small. Our main results are established using variational "hypocoercive" methods, localization techniques and semiclassical subelliptic estimates., Comment: 38 pages, 4 figures

Published
2008

3. Function and regulation of Fizz1 and Ym1 in Th2 inflammation

Author

Gallagher, I. J.

Subjects
616.079
Abstract

The elucidation of the macrophage activation pathways stimulated by the innate recognition of bacterial products and the T helper 1 (Th1) cytokine IFN-γ which lead to a proinflammatory or “classically activated” macrophage phenotype is well underway. However macrophages can also be activated by Th2 cytokines such as IL-4 and IL-13, by Fc receptor ligation and by hormonal influences such as glucocorticoids. Macrophage exposure to IL-4 and / or IL-13 leads to “alternative activation” and alternatively activated macrophages have been implicated in the response against helminth parasites and in wound healing. We have developed a model system for generating alternatively activated macrophages in vivo. Implant of the filarial nematode Brugia malayi into the peritoneal cavity of mice gives rise to a cellular response dominated by macrophages with a profoundly Th2 dependent phenotype. These nematode elicited macrophages (NeMΦ) are potent suppressors of cellular proliferations and express the enzyme Arginasel, a marker of alternative activation as well as two further markers of alternative macrophage activation, Ym1 and Fizz1. We investigated the kinetics of the NeMΦ phenotype and found that whilst late expression of Arginasel Fizz1 and Ym1 was a driven by an adaptive Th2 response these genes were also expressed at the earliest timepoints after implant indicating that they had a role in the response to the surgical procedure used to implant B. malayi. The early, injury associated expression of Arginasel mRNA we found to be dependent on IL-4 whilst Fizz1 and Ym1 mRNA expression in this context was dependent on IL-13 signalling through the IL-4Rα. We also found that Fizz1 and Ym1 expression were confined to the lung stage of infection with the gastrointestinal nematode Nippostrongylus brasiliensis where these genes may play a role in the regenerative response after the parasite migration through this tissue. Finally an examination of the regulation of these genes in a trematode model and found that, surprisingly, Fizz1 and Ym1 expression may also be controlled by IFN-γ perhaps through modulation of IL-13 activity.

Published
2006

4. Splash: Speech and language assessment in schools and homes

Author

Miwardelli, A, Gallagher, I, Gibson, J, Katsos, N, Knill, K, and Wood, H

Subjects
screening app, speech disorders
Abstract

Copyright © 2019 ISCA This paper presents a tablet-based app for Speech and Language Assessment in Schools and Homes (Splash) to provide a first screening for young children aged 4-6 years to assess their speech and language skills. The app aims to be easy-to-administer with an adult, such as a teacher or parent, directing the child through the tasks. Three fun games have been developed to assess receptive language, expressive language and connected speech, respectively. Currently in proof-of-concept mode, when complete Splash will use automatic spoken language processing to give an instant estimate of a child's communication ability and provide guidance on whether to speak specialist support. While not a diagnostic tool, the aim is for Splash to be used to provide immediate reassurance or direction to concerned parents, guardians or teachers as it can be administered by anyone, anywhere.

Published
2023
Full Text
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6. BJS commission on surgery and perioperative care post-COVID-19

Author

Abahuje, E, Abbas, A, Abd El Aziz Abd El Maksoud, M, Abdelhady, A, Abdelhamid, S, Abdelkarem Ahmed Faraj, H, Abdelqader, B, Abdelrahman, T, Abdou, H, Abdullah, A, Abedua Harrison, M, Abem Owusu, E, Aboalazayem, A, Aboulhosn, R, Abu Oda, S, Abubakar, A, Abutaka, A, Acevedo Fontalvo, D, Acuna, S, Adefemi, A, Adegbola, S, Adenuga, T, Adeyeye, A, Adil Hilmi, A, Adisa, A, Aditya, K, Adjeso, T, Aftab, R, Afzal, A, Aggarwal, V, Aggarwal, A, Aguilera, R, Aguilera-Arevalo, M, Aguirre Salamanca, E, Aguirre-Allende, I, Ahari, D, Ahmad, H, Ahmad Rauf, F, Ahmad Zartasht Khan, A, Ahmed, S, Ahmed Fieturi, N, Ahmed Mohamed, S, Ahmed-Bakhsh, Z, Ahsan Javed, M, Akano, L, Akbar, A, Akhbari, M, Akhmedov, P, Aksit, G, Akula, Y, Alagaratnam, A, Al Majid, S, Al Mukhtar, O, Al Omran, H, Alasali, N, Al-Azzawi, M, Al-Habsi, R, Al-Iraqi, H, Al-Naggar, H, Alameer, E, Albirnawi, H, Alderson, D, Aldulaijan, F, Alejandro Miranda Ojeda, R, Alhasan, A, Ali, S, Ali, A, Ali Khan, M, Alimova, Y, Aljanadi, F, Aljubure, R, Allopi, N, Almedbal, H, Almubarak, M, Alqaidoom, Z, Alselaim, N, Alshaar, M, Alshammari, R, Altaf, K, Altiner, S, Altunpak, B, Alvarez Lozada, L, Amal Nahal, E, Amer, A, Amin, K, Aminu, U, Amisi Numbi, N, Amjad, T, Amoah, R, An, Y, Anastasopoulos, N, Andres Urrutia, J, Angarita, F, Angarita, K, Angel Freiria Eiras, M, Antypas, A, Anwar, M, Anwar, H, Apampa, T, Apostolou, K, Aquina, C, Arachchige Adithi Himika Randeni, R, Archila Godinez, M, Arez, O, Arezzo, A, Armonis, P, Arshad, S, Arshad Salman, M, Arshid, A, Arteaga Asensio, P, Arthur, T, Arumuga Jothi, A, Aryo Damara, F, Asensio Gomez, L, Ashcroft, J, Ashraf, S, Asif, A, Atif, M, Attaullah Khan, M, Avellaneda, N, Awad, S, Awadh, M, Axiaq, A, Ayad Mohammed Shuwayyah, A, Ayalew, D, Aytac, E, Azam, F, Azevedo, J, Azhar, B, Aziz, J, Aziz, A, Azzam, A, Baba Ndajiwo, A, Baig, M, Baker, D, Bakko, F, Balachandran, R, Balachandran, G, Balagizi Mudekereza, J, Balai, E, Balci, B, Balduzzi, A, Balhareth, A, Bandyopadhyay, S, Banerjee, D, Bangalore Mahalinga, D, Bankhead-Kendall, B, Bankole, N, Banwell, V, Baris Bengur, F, Baris Ozmen, B, Barnard, M, Barnett, R, Barreras Espinoza, J, Barrios, A, Bass, G, Bass, M, Bausys, A, Bavikatte, A, Bayram, J, Belousov, M, Berardi, A, Beamish, A, Beattie, C, Belia, F, Bellato, V, Bellikatti, S, Benjamens, S, Benlice, C, Bennedsgaard, S, Bennett, S, Bentounsi, Z, Bergenfeldt, H, Bergenfelz, A, Besselink, M, Bhandoria, G, Bhangu, E, Bhatia, M, Bhatti, M, Bilgili, Z, Bislenghi, G, Bisset, C, Biswas, S, Blake, J, Blanco, R, Boccalatte, L, Boden, R, Bojanic, C, Boland, M, Boland, P, Bollen, E, Bonci, E, Boni, L, Booth, A, Booth, R, Borakati, A, Borunda Escudero, G, Bosco, S, Bostrom, P, Botelho De Alencar Ferreira Cruz, P, Bouchagier, K, Bouhuwaish, A, Boutros, M, Boyce, K, Boyle, C, Bradshaw, L, Brandl, A, Brar, A, Brat, G, Brenkman, H, Brennan, C, Brines, C, Brookmyre, A, Brosnan, C, Brouwers, L, Brown, A, Brown, L, Brown, C, Brown, J, Bs, V, Buksh, M, Bunani Emmanuel, M, Burbano, D, Burelli, A, Burke, A, Burke, J, Burlov, N, Burns, A, Burton, O, Butt, A, Buzra Ozkan, B, Cabrera Silva, L, Caicedo, E, Calderbank, T, Cambridge, W, Campelo, G, Can Tatar, O, Carbone, F, Carrano, F, Casallas, D, Casanova Portoles, D, Casciani, F, Cassimjee, I, Castaneda Ramirez, O, Catalan, V, Caviedes, J, Cayetano, L, Ceresoli, M, Chan, M, Chan, V, Chandrasinghe, P, Chapman, S, Chaturvedi, A, Chaudhry, D, Chaudry, H, Chen, H, Cheng, A, Chernykh, M, Cherrie, A, Cheruiyot, I, Cheung, J, Chia, C, Chica, J, Chinai, N, Chirwa, A, Chiwaligo, J, Choi, A, Choi, J, Chowdhury, M, Christopher, E, Christou, N, Chu, T, Chua, D, Chua, H, Chung, C, Cihat Yildirim, A, Cillo, M, Cioffi, S, Claireaux, H, Clermonts, S, Clifford, R, Climent, M, Clynch, A, Coelen, R, Colas-Ruiz, E, Collar, A, Collard, M, Conlon, K, Connelly, T, Connor, K, Cook, J, Correia De Sa, T, Cosgun Acar, N, Costa, T, Couch, D, Cowper, S, Creavin, B, Crook, B, Curell, A, D'Alessio, R, Dale, J, Damgaard Eriksen, J, Dario Martin Gonzalez, I, Darwish, A, Das, M, Das, R, Das, K, Dave, R, David, S, Davies, T, Davis, C, Davison, S, Davletshina, V, Dawidziuk, A, Dawson, A, De Andres Crespo, M, De Berker, H, De Dieu Ngo, P, Dekker, E, De La Caridad Espinosa Luis, R, De Lacy, B, Demartines, N, De Montserrat Medina Sifuentes, A, De Silva, S, Del Rio, C, Delaune, V, Dell, A, Demirbas, I, Demirli Atici, S, Deniz Tepe, M, Derebey, M, Desai, G, Desai, M, Devarakonda, S, Deveras, N, Di Franco, G, Di Martino, M, Di Marzo, F, Diaz, A, Diaz Del Gobbo, G, Diazcastrillon, C, Dick, L, Dickinson, K, Diego, E, Dimasi, I, Ding, A, Dingemans, S, Dixon, L, Dixon, B, Doherty, W, Dooreemeah, D, Donohue, C, Dornseifer, M, Dossa, F, Dossou, W, Drake, T, Drami, I, Drevin, G, Du Plessis, M, Dudi-Venkata, N, Dudley, R, Duffy, S, Duklas, D, Dumbrava, B, Duygu Avlar, F, Dworzynska, A, Ebrahim, W, Ebrahim, A, Efren Lozada Hernandez, E, Ehigie, N, El Boghdady, M, El Hasnaoui, C, El Sheikh, M, El-Hussuna, A, Eldurssi, O, Elfeki, H, Elhadi, M, Elhassan, M, Elhissi, A, Elliot, B, Elsenbroek, C, Elsolh, B, Elson, N, Eltyeb, H, Emerson, H, Emile, S, Endalle, G, English, W, Ercisli, C, Espinosa, G, Essam Abdelraheem, M, Essangri, H, Etienne, P, Evans, M, Evans, T, Ezeme, C, Ezzahraa, F, Fadalla, T, Fagan, J, Fahmy, M, Fairfield, C, Falade, O, Famularo, S, Faqar-Uz-Zaman, F, Farid, Y, Farooq, A, Farooq, H, Farooqui, F, Farquharson, B, Faruqi, A, Faulder, R, Faut, M, Fechner, K, Feenstra, T, Fehervari, M, Fernandez, L, Fernandez Alberti, J, Ferrario, L, Field, D, Fiore, L, Fingerhut, S, Finlayson, S, Fleming, N, Fleming, C, Florial, E, Fok, M, Fokin, D, Foley, M, Forero, M, Forgan, T, Fornasiero, M, Fowler, H, Fowler, G, Franchi, E, Franklin, L, Fredriksson, A, Fruhling, P, Fuentes Navarrette, G, Fulop, A, Furtado, M, Gaarder, T, Galbraith, N, Gallagher, I, Gallo, G, Gana, T, Gaskin, E, Gasparini, M, Gatan, R, Geary, E, Gelaye Wudineh, K, Gemenetzis, G, Georgi, M, Ghalige, H, Ghareeb, W, Ghatwary Tantawy, T, Ghomsi, C, Ghuman, A, Giannakis, P, Giron, F, Gjengedal, K, Gkotsis, E, Glasbey, J, Godahewa, S, Godula, D, Goffredo, P, Goh, S, Golriz, M, Gomez, L, Gomez Gomez, D, Gonzalez, R, Gonzalez, D, Gonzalez Gutierrez, E, Gopar, D, Gordini, L, Gori, A, Gortazar, S, Gousy, N, Gowda, R, Gowda, M, Gqada, J, Grechenig, M, Greer, J, Gregorio, L, Grigorova, A, Grimes, H, Groot, V, Grossman, R, Gruber, R, Gruter, A, Guest, R, Gujjuri, R, Gulcek, E, Gulcu, B, Gull, K, Gulmez, M, Gupta, V, Gutlic, A, Guven, T, Gwatirisa, T, Gwini, G, Gwodog, P, Gysling, S, Habib, M, Hafeez Bhatti, A, Hallesmith, J, Halloran, S, Hamza Sadiq, M, Haney, C, Hanna, N, Hanna, L, Hannington, M, Harbjerg, J, Haribaskaran, D, Harran, N, Harrington, B, Harrison, E, Hasan, R, Hashmi, S, Hassan, M, Hassan, A, Haverkamp, L, Hazen, S, Heer, B, Heil, J, Helliwell, J, Henriksen, N, Henshall, D, Hermanson, M, Hermena, S, Hettiarachchi, D, Hextall, C, Hidalgo, M, Hidayat, H, Hider, A, Higgins, P, Hinchliffe, R, Hirani, D, Hirpara, D, Hisham, I, Hite, M, Hoh, S, Holmberg, C, Holmich, E, Holst, F, Hossam, A, Hossam Elfallal, A, Howard, P, Huaman, E, Huang, Y, Huang, L, Huang, D, Huber, T, Hugh, J, Hughes, J, Huttner, F, Huynh, R, Hylands, A, Iannuzzi, J, Ielpo, B, Iftikhar Talib, A, Ignacio, J, Ignatavicius, P, Ike, S, Ikwu, C, Inama, M, Ing, A, Ingels, A, Isik, A, Islam, N, Ives, I, Al-Hasan, A, Perez Rivera, C, Jacome, F, Jaffer, T, Jagiella-Lodise, O, Jain, M, Jain, K, Jakubauskas, M, Jalal, M, James, H, Jang, Y, Janssen, B, Jansson, H, Jariod-Ferrer, U, Javanmard, H, Javed, S, Jayarajah, U, Jayasuriya, I, Je, J, Jessop, Z, Jia Lin Tang, E, Jiang, H, Jiayan, Y, Jih Huei, T, Jimenez-Rodriguez, R, Joh, D, Johnson, A, Jones, N, Jones, C, Jordan, C, Jose Nunez Ju, J, Jose Pizarro, M, Jose Salazar, C, Joseph, J, Justiniano, C, Kabir, T, Kadhum, M, Kalfountzos, C, Kalogiannaki, E, Kalyanasundaram, K, Kamarajah, S, Kamil Quraishi, M, Kanemitsu, Y, Kapila, A, Kapila, V, Karagiannidis, G, Kashif, M, Kathiravelupillai, S, Kathiravelupillai, A, Katsogridakis, E, Kaur, K, Kaur Sekhon Inderjit Singh, H, Kausur, N, Kawka, M, Keehan, G, Kehlet Watt, S, Kelly, M, Kelvin Egbuchulem, I, Kembuan, G, Khajeh, E, Khaled Elfaitur, A, Khan, M, Khan, S, Khan, D, Khan, H, Khatkar, H, Khatkov, E, Khaw, R, Kim, B, Kishore Siddiraju, K, Kitua, D, Kirimtay, B, Kmezic, S, Knight, S, Koeter, T, Koh, A, Koh Hong Xiang, F, Kojo Anyomih, T, Kok, A, Kokelaar, R, Koliarakis, I, Kolli, S, Kong, J, Konig, D, Koshy, M, Kotze, P, Kourdouli, A, Kowal, M, Kraima, A, Kramer, F, Kryzauskas, M, Kuchynskyi, I, Kuemmerli, C, Kuiper, S, Kumar, S, Kumar, A, Kumar, L, Kumar, H, Kumar, N, Kumar Bandyopadhyay, S, Kumar Garg, P, Kumar Venkatappa, S, Kung, J, Kural, S, Kushairi, A, Kuuzie, E, Kvietkauskas, M, Kwek, I, La, J, Lai, L, Lakpriya, S, Lam, K, Lami, M, Lansdorp-Vogelaar, I, Lapolla, P, Larsen, H, Latif, J, Laudari, U, Laurnezi, A, Lawal, A, Lawday, S, Lederhuber, H, Lednev, A, Lee, R, Van Leerdam, M, Lefevbre, G, Lesmus, M, Leyva Moraga, F, Leyva Moraga, E, Li, H, Li, A, Li, Z, Licardie, E, Light, A, Lightner, A, Lin, A, Lincango, E, Litta, F, Liu, H, Lofthouse, B, Londono, M, Lopes, R, Lopes De Freitas, R, Lopez, L, Lopez, A, Lopez-Gomez, J, Lopez-Pena, G, Lowe, R, Lowe, D, Lowey, M, Loy, G, Lozanovski, V, Luzon, J, Lynn, P, Maccabe, T, Machielsen, A, Mafla Herreria, C, Maggino, L, Mahawar, K, Mahmood, D, Mahmoud, M, Mahtani, K, Maitra, I, Maji, S, Majiet, I, Mal, L, Malherbe, J, Malhotra, K, Malkomes, P, Man, E, Manan Sheikh, A, Manjunath, S, Manzano Nunez, R, Manzoor, S, Maqsood, R, Marchegiani, G, Marchegiani, F, Marin, D, Marin, A, Marks, I, Marson, E, Martensen, A, Martin, D, Martin Martin, G, Martin-Perez, B, Martinez, P, Marwaha, P, Mashauri, C, Mashbari, H, Masior, L, Masri, R, Masud, L, Masudi, S, Mateu Calabuig, G, Math, S, Matrachisia, A, Mayol, J, Mazingi, D, Mazzotta, A, Mcalinden, J, Mccabe, G, Mccolm, L, Mcelvaney, H, Mcgivern, K, Mcgovern, J, Mcguinness, E, Mcinerney, N, Mckay, S, Mckee, C, Mckenna, M, Mckenna, N, Mclean, K, Mediratta, S, Medkova, Y, Medzhidov, O, Mehraj, A, Mekhael, M, Mekinde, O, Mellenthin, C, Melucci, A, Mentor, K, Merchant, J, Messias, H, Messeha, M, Meza, C, Mhango, P, Miladinov, M, Milagros Niquen Jimenez, M, Miller, P, Mills, E, Milton, A, Minayeva, O, MinHua Zheng, Z, Mischlinger, H, Mockli, B, Modi, R, Mohamed, H, Mohamed, M, Mohamed Abulghasm, T, Mohammad, S, Mohammed, T, Mohammed, A, Mohan, H, Mohan, M, Moin, I, Mok, V, Molina, G, Moloney, J, Moneim, J, Monfort Mira, M, Montcusi Ventura, B, Montouri, M, Moossdorff, M, Mora-Guzman, I, Moran, B, Moran, R, Moreno-Ordaz, S, Morera, A, Morgan, R, Morley, R, Moro-Valdezate, D, Moros, S, Moss, J, Morven, A, Morton, D, Moynihan, A, Moyon, M, Muduli, N, Mugla, N, Mugla, W, Muller, P, Mun, G, Mundhada, R, Munir, I, Munoz, F, Munoz, E, Munoz, A, Munoz Balderas, D, Murgitroyd, E, Murray, V, Murthy, S, Mushiwokufa, W, Mustafa, H, Mustakimov, B, Mutambanengwe, P, Myint, P, Nadkarni, S, Naess, P, Nahar, S, Naidoo, P, Nam, R, Nandhra, S, Nanjappa, N, Narasimhan, V, Nardi, W, Nasir, M, Naughton, A, Naumann, D, Navarro, S, Nawaaz Karimbocus, M, Nazir, A, Ndereya, S, Ndong, A, Negoi, I, Nel, D, Nelson, D, Nepal, S, Nugent, T, Nepogodiev, D, Neufeld, J, Ng, J, Ng, D, Ng, C, Ngaserin, S, Ngu, L, Ngwenya, E, Fhearaigh, R, Nikolousakis, T, Ninkovic, M, Nita, G, Nitschke, C, Noren, E, Noton, T, Novikova, A, Nowinka, Z, Nyakunengwa, T, Nyalundja, A, Nzenwa, I, Kristensen, H, O'Brien, C, O'Brien, L, O'Brien, S, O'Reilly, J, O'Rourke, S, O'Sullivan, M, O'Dwyer, M, Ochieng, L, Oderoha, E, Oh, K, Ohlberger, L, Olcum, M, Olkina, A, Omkumar, M, Omnitel, B, Oncel Yakar, D, Ong, K, Ong Wei Lin, L, Ooi, R, Ooi, S, Oomman, A, Oon Tyjet, D, Opiyo, S, Oscullo Yepez, J, Osei-Kuffour, N, Osunronbi, T, Ottlakan, A, Oussama Kacimi, S, Ovaere, S, Ozair, A, Pachler, F, Pai Oo, S, Paiella, S, Panaiotti, L, Panda, N, Pandarinath, S, Pandey, D, Pandrowala, S, Papa Mamadou, F, Paranathala, M, Park, J, Parmar, C, Parvez, A, Pasovic, L, Pasquer, A, Pasumarthy, N, Pata, F, Patel, T, Patel, P, Patel, N, Patel, M, Patron Uriburu, N, Patrone, R, Paul, A, Pavan Kumar, O, Pavithran, A, Pedraza Ciro, M, Pellino, G, Peloso, A, Pena Gallardo, M, Pena Velazquez, A, Perea, J, Perez-Sanchez, L, Perra, T, Perrotta, G, Petersson, P, Petra, G, Petrucciani, N, Pickin, C, Pino, V, Pinotti, E, Pinto, F, Plum, P, Podesta, F, Pollini, T, Pompeu Sa, M, Ponce Leon, F, Ponniah, H, Ponte De Sousa, X, Ponton, J, Pontula, A, Popa, M, Portilla, A, Posner, F, Post, S, Potolicchio, A, Pouwels, S, Povo, A, Prasad, P, Preciado, S, Preece, R, Proud, D, Pulido Segura, J, Puliyath, N, Qui, M, Quimbaya Rodriguez, A, Raby-Smith, W, Racovita, A, Rad, A, Radwan, R, Rafaih Iqbal, M, Rafik, A, Raguan, B, Rahi, M, Rahiri, J, Rahme, J, Rai, L, Raj, A, Raj Saksena, A, Raja, M, Ramirez, J, Ramzi, J, Ranstam, J, Rao, C, Rashid, A, Ratnayake, B, Rattanasirivilai, K, Raubenheimer, K, Ravikumar, N, Ravn, S, Razoz, N, Rea, W, Regan, A, Rela, M, Remme, A, Rey Chaves, C, Reyes, A, Riad, A, Rice, D, Rios Quintana, K, Ritter, A, Roalso, M, Robinson, D, Rodriguez, J, Rodriguez, F, Rodriguez, M, Rogers, A, Rohila, J, Romanyuc, D, Romic, I, Rommaneh, M, Rompianesi, G, Rosa, F, Roscio, F, Rose, A, Rotimi, T, Ruiz, H, Ruiz Yucuma, J, Ruiz-Ucar, E, Ruslan, M, Rutegard, M, Ryan Harper, E, Ryckx, A, Rydbeck, D, Sa-Marta, E, Sadien, I, Safari Nteranya, D, Sagoo, K, Sakata, S, Saladino, E, Saleem, A, Saleem, S, Salehi, M, Salih, S, Sallinen, V, Salvans, S, Sam, Z, Samadov, E, Sampaio Alves, M, Sanad, A, Sanchez Fonseca, S, Sanchez Teran, A, Sanchez Ussa, S, Sandli, O, Sanfey, H, Sanghera, J, Sani, I, Santafe Guerrero, M, Sante Fornasiero, M, Santes Jasso, O, Santos Pereira, I, Santos Sousa, H, Saratzis, A, Sarmiento Alarcon, A, Saumtally, T, Sayyed, R, Schettino, M, Schleimer, L, Schmidt, T, Schondffelt, K, Schwab, M, Scott, A, Searle, H, Sebopelo, L, Seeglier, B, Seishima, R, Semenvov, D, Senent-Boza, A, Sepulveda, J, Serenari, M, Serrano Navidad, M, Sert, I, Sewart, E, Sgro, A, Shadrina, V, Shah, K, Shahid, F, Shalaby, M, Shankar, B, Shapiro, J, Sharma, L, Sheel, A, Shenfine, A, Shenoy, S, Sherif, A, Shetty, N, Shetty, R, Sia, T, Sichimba, D, Siddique, H, Siddiqui, I, Simkens, G, Simoe, J, Simon, H, Sinan, L, Singh, T, Singh, K, Singh, Y, Sinha, L, Siragusa, L, Sluckin, T, Smart, Y, Smith, H, Smith, K, Smits, L, Sneep-Van Kessel, C, Sohrabi, C, Solorzano Pineda, O, Soma, A, Sooriyapiragasam, L, Soreide, K, Sparavigna, M, Spence, R, Spencer, N, Spiers, H, Spinelli, A, Sprakel, J, Sravanam, S, Srinivasan, M, Srinivasan, R, Staniszewska, A, Stanworth, S, Stasinos, K, Steele, R, Steinholt, I, Steinruecke, M, Stephen, B, Stijns, J, Still, M, Stupalkowska, W, Subba, S, Subbotin, V, Sucharitkul, P, Sudarsanam, A, Sudhamsh Reddy, D, Suhardja, T, Suliman, M, Sund, M, Sunilkumar, A, Suresh, N, Sussmes, S, Sutton, P, Syltern, J, Taha, A, Takamizawa, Y, Takoutsing Dongmo, A, Tamas, T, Tan, L, Tan, J, Tan, K, Tan, E, Tan Yong Hui, A, Tanase, A, Tariverdiev, A, 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A., MinHua Zheng Z., Mischlinger H., Mockli B., Modi R., Mohamed H. M., Mohamed M., Mohamed Abulghasm T., Mohammad S. A., Mohammed T. O., Mohammed A., Mohan H., Mohan M., Moin I., Mok V., Molina G., Moloney J., Moneim J., Monfort Mira M., Montcusi Ventura B., Montouri M., Moossdorff M., Mora-Guzman I., Moran B., Moran R. A. R., Moreno-Ordaz S., Morera A., Morgan R., Morley R., Moro-Valdezate D., Moros S., Moss J. -L., Morven A., Morton D., Moynihan A., Moyon M., Muduli N., Mugla N., Mugla W., Muller P., Mun G., Mundhada R., Munir I., Munoz F., Munoz E., Munoz A., Munoz Balderas D. C., Murgitroyd E., Murray V., Murthy S., Mushiwokufa W., Mustafa H., Mustakimov B., Mutambanengwe P., Myint P., Nadkarni S., Naess P. A., Nahar S., Naidoo P., Nam R., Nandhra S., Nanjappa N., Narasimhan V., Nardi W., Nasir M., Naughton A., Naumann D., Navarro S., Nawaaz Karimbocus M., Nazir A., Ndereya S., Ndong A., Negoi I., Nel D., Nelson D., Nepal S., Nugent T., Nepogodiev D., Neufeld J., Ng J., Ng D., Ng C. E., Ngaserin S., Ngu L., Ngwenya E., Fhearaigh R. N., Nikolousakis T. -K., Ninkovic M., Nita G., Nitschke C., Noren E., Noton T., Novikova A., Nowinka Z., Nyakunengwa T., Nyalundja A., Nzenwa I., Kristensen H. O., O'Brien C., O'Brien L., O'Brien S., O'Reilly J., O'Rourke S., O'Sullivan M., O'Dwyer M., Ochieng L., Oderoha E., Oh K. E., Ohlberger L., Olcum M., Olkina A., Omkumar M., Omnitel B., Oncel Yakar D., Ong K., Ong Wei Lin L., Ooi R., Ooi S., Oomman A., Oon Tyjet D., Opiyo S., Oscullo Yepez J. J., Osei-Kuffour N., Osunronbi T., Ottlakan A., Oussama Kacimi S., Ovaere S., Ozair A., Pachler F., Pai Oo S., Paiella S., Panaiotti L., Panda N., Pandarinath S., Pandey D., Pandrowala S., Papa Mamadou F., Paranathala M., Park J., Parmar C., Parvez A., Pasovic L., Pasquer A., Pasumarthy N., Pata F., Patel T., Patel P., Patel N., Patel M., Patron Uriburu N., Patrone R., Paul A., Pavan Kumar O. M., Pavithran A., Pedraza Ciro M., Pellino G., Peloso A., Pena Gallardo M. T., Pena Velazquez A., Perea J., Perez-Sanchez L. E., Perra T., Perrotta G., Petersson P., Petra G., Petrucciani N., Pickin C., Pino V., Pinotti E., Pinto F., Plum P., Podesta F., Pollini T., Pompeu Sa M., Ponce Leon F., Ponniah H. S., Ponte De Sousa X., Ponton J., Pontula A., Popa M., Portilla A. L., Posner F., Post S., Potolicchio A., Pouwels S., Povo A., Prasad P., Preciado S., Preece R., Proud D., Pulido Segura J. A., Puliyath N., Qui M., Quimbaya Rodriguez A. S., Raby-Smith W., Racovita A., Rad A., Radwan R., Rafaih Iqbal M., Rafik A., Raguan B., Rahi M., Rahiri J. -L., Rahme J., Rai L., Raj A., Raj Saksena A., Raja M., Ramirez J., Ramzi J., Ranstam J., Rao C., Rashid A., Ratnayake B., Rattanasirivilai K., Raubenheimer K., Ravikumar N., Ravn S., Razoz N., Rea W., Regan A., Rela M., Remme A., Rey Chaves C. E., Reyes A., Riad A., Rice D., Rios Quintana K., Ritter A., Roalso M., Robinson D., Rodriguez J., Rodriguez F., Rodriguez M. C., Rogers A., Rohila J., Romanyuc D., Romic I., Rommaneh M., Rompianesi G., Rosa F., Roscio F., Rose A., Rotimi T., Ruiz H., Ruiz Yucuma J., Ruiz-Ucar E., Ruslan M., Rutegard M., Ryan Harper E., Ryckx A., Rydbeck D., Sa-Marta E., Sadien I., Safari Nteranya D., Sagoo K., Sakata S., Saladino E., Saleem A., Saleem S., Salehi M., Salih S., Sallinen V., Salvans S., Sam Z. 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F., Khan S., Khan M., Khan D., Khan H., Khatkar H., Khatkov E., Khaw R., Kim B., Kishore Siddiraju K., Kitua D., Kirimtay B., Kmezic S., Knight S., Koeter T., Koh A., Koh Hong Xiang F., Kojo Anyomih T., Kok A. I. N., Kokelaar R., Koliarakis I., Kolli S., Kong J., Konig D., Koshy M., Kotze P., Kourdouli A., Kowal M., Kraima A., Kramer F., Kryzauskas M., Kuchynskyi I., Kuemmerli C., Kuiper S., Kumar S., Kumar A., Kumar L., Kumar H., Kumar N., Kumar Bandyopadhyay S., Kumar Garg P., Kumar Venkatappa S., Kung J., Kural S., Kushairi A., Kuuzie E., Kvietkauskas M., Kwek I., La J., Lai L., Lakpriya S., Lam K., Lami M., Lansdorp-Vogelaar I., Lapolla P., Larsen H., Latif J., Laudari U., Laurnezi A., Lawal A., Lawday S., Lederhuber H., Lednev A., Lee R., Van Leerdam M. E., Lefevbre G., Lesmus M., Leyva Moraga F. A., Leyva Moraga E., Leyva Moraga F., Li H. L., Li A., Li Z., Licardie E., Light A., Lightner A. L., Lin A., Lincango E., Litta F., Liu H., Lofthouse B., Londono M. 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A., Nahar S., Naidoo P., Nam R., Nandhra S., Nanjappa N., Narasimhan V., Nardi W., Nasir M., Naughton A., Naumann D., Navarro S., Nawaaz Karimbocus M., Nazir A., Ndereya S., Ndong A., Negoi I., Nel D., Nelson D., Nepal S., Nugent T., Nepogodiev D., Neufeld J., Ng J., Ng D., Ng C. E., Ngaserin S., Ngu L., Ngwenya E., Fhearaigh R. N., Nikolousakis T. -K., Ninkovic M., Nita G., Nitschke C., Noren E., Noton T., Novikova A., Nowinka Z., Nyakunengwa T., Nyalundja A., Nzenwa I., Kristensen H. O., O'Brien C., O'Brien L., O'Brien S., O'Reilly J., O'Rourke S., O'Sullivan M., O'Dwyer M., Ochieng L., Oderoha E., Oh K. E., Ohlberger L., Olcum M., Olkina A., Omkumar M., Omnitel B., Oncel Yakar D., Ong K., Ong Wei Lin L., Ooi R., Ooi S., Oomman A., Oon Tyjet D., Opiyo S., Oscullo Yepez J. J., Osei-Kuffour N., Osunronbi T., Ottlakan A., Oussama Kacimi S., Ovaere S., Ozair A., Pachler F., Pai Oo S., Paiella S., Panaiotti L., Panda N., Pandarinath S., Pandey D., Pandrowala S., Papa Mamadou F., Paranathala M., Park J., Parmar C., Parvez A., Pasovic L., Pasquer A., Pasumarthy N., Pata F., Patel T., Patel P., Patel N., Patel M., Patron Uriburu N., Patrone R., Paul A., Pavan Kumar O. M., Pavithran A., Pedraza Ciro M., Pellino G., Peloso A., Pena Gallardo M. T., Pena Velazquez A., Perea J., Perez-Sanchez L. E., Perra T., Perrotta G., Petersson P., Petra G., Petrucciani N., Pickin C., Pino V., Pinotti E., Pinto F., Plum P., Podesta F., Pollini T., Pompeu Sa M., Ponce Leon F., Ponniah H. S., Ponte De Sousa X., Ponton J., Pontula A., Popa M., Portilla A. L., Posner F., Post S., Potolicchio A., Pouwels S., Povo A., Prasad P., Preciado S., Preece R., Proud D., Pulido Segura J. A., Puliyath N., Qui M., Quimbaya Rodriguez A. S., Raby-Smith W., Racovita A., Rad A., Radwan R., Rafaih Iqbal M., Rafik A., Raguan B., Rahi M., Rahiri J. -L., Rahme J., Rai L., Raj A., Raj Saksena A., Raja M., Ramirez J., Ramzi J., Ranstam J., Rao C., Rashid A., Ratnayake B., Rattanasirivilai K., Raubenheimer K., Ravikumar N., Ravn S., Razoz N., Rea W., Regan A., Rela M., Remme A., Rey Chaves C. E., Reyes A., Riad A., Rice D., Rios Quintana K., Ritter A., Roalso M., Robinson D., Rodriguez J., Rodriguez F., Rodriguez M. C., Rogers A., Rohila J., Romanyuc D., Romic I., Rommaneh M., Rompianesi G., Rosa F., Roscio F., Rose A., Rotimi T., Ruiz H., Ruiz Yucuma J., Ruiz-Ucar E., Ruslan M., Rutegard M., Ryan Harper E., Ryckx A., Rydbeck D., Sa-Marta E., Sadien I., Safari Nteranya D., Sagoo K., Sakata S., Saladino E., Saleem A., Saleem S., Salehi M., Salih S., Sallinen V., Salvans S., Sam Z. H., Samadov E., Sampaio Alves M., Sanad A., Sanchez Fonseca S., Sanchez Teran A., Sanchez Ussa S., Sandli O., Sanfey H., Sanghera J., Sani I., Santafe Guerrero M., Sante Fornasiero M., Santes Jasso O., Santos Pereira I., Santos Sousa H., Saratzis A., Sarmiento Alarcon A., Saumtally T., Sayyed R., Schettino M., Schleimer L., Schmidt T., Schondffelt K., Schwab M., Scott A., Searle H., Sebopelo L., Seeglier B., Seishima R., Semenvov D., Senent-Boza A., Sepulveda J., Serenari M., Serrano Navidad M., Sert I., Sewart E., Sgro A., Shadrina V., Shah K., Shahid F., Shalaby M., Shankar B., Shapiro J., Sharma L., Sheel A., Shenfine A., Shenoy S., Sherif A., Shetty N., Shetty R., Sia T. C., Sichimba D., Siddique H., Siddiqui I., Simkens G., Simoe J., Simon H., Sinan L., Singh T., Singh K., Singh Y., Sinha L., Siragusa L., Sluckin T., Smart Y. W., Smith H., Smith K., Smits L., Sneep-Van Kessel C., Sohrabi C., Solorzano Pineda O., Soma A., Sooriyapiragasam L., Soreide K., Sparavigna M., Spence R., Spencer N., Spiers H., Spinelli A., Sprakel J., Sravanam S., Srinivasan M., Srinivasan R., Staniszewska A., Stanworth S. J., Stasinos K., Steele R. J. C., Steinholt I., Steinruecke M., Stephen B. -J., Stijns J., Still M., Stupalkowska W., Subba S., Subbotin V. V., Sucharitkul P., Sudarsanam A., Sudhamsh Reddy D., Suhardja T., Suliman M., Sund M., Sunilkumar A., Suresh N., Sussmes S., Sutton P., Syltern J., Taha A., Takamizawa Y., Takoutsing Dongmo A. B., Tamas T., Tan L., Tan J. L., Tan K., Tan E., Tan Yong Hui A., Tanase A., Tariverdiev A., Tasnem A., Tatar C., Tay E., Tejedor P., Tesfaye G., Tetinou F., Thorpe C., Thyo A., Tlelo Amastal D., Tolani M., Tolga Saracoglu K., Tolgyes T., Tong J., Torrent Jansa L., Toscano Igartua S., Tovani Palone M. R., Traff H., Trevis J., Tummers W., Tur A., Turchenko I., Uche V., Uddin A., Udonsak N., Ullah M., Urbonas T., Uwins C., Uy Magadia E., Uzair Qureshi A., Uzun K., Vadim P., Valarche G., Valdez Gonzalez R. A., Vallee M., Van Beek D. -J., Van Dalen A. S., Van Den Hondel D., Van Der Stok E., Van Dorp M., Van Oostendorp S., Van Praag E., Van Rees J., Van Silfhout L., Varga Z., Varghese S., Varghese C., Varghese J., Vasilica A. -M., Vasquez Ojeda X., Vega E., Vehler S., Venchiarutti R., Vengatesan S., Venn M., Verma D., Vianey Partida Nava G., Victoria D., Vieira P., Vilar Alvarez M. E., Vinci D., Viscasillas Pallas G., Viswanath M., Vivanco J., Vizcaya Rodriguez V., Vo J., Volchanski D., Voron T., Voronovskyi Y., Vu J., Wadhwa M., Wadhwa S., Wagner G., Wallace M., Wang Y. Y., Wang J., Wani A., Wanigasooriya K., Wanjara S., Wanjiku N., Warner C., Wei Leow T., Weiser T., Weisters M., Wellington M. J., Wells C., Wenzelberg C., Wettstein D., Wezel A., Wheldon L., Widmer L., Wilson M., Wigmore S., Wijayaratne T., Wijeyaratne M., Wijnhoven B. P. L., Wilkin R., Williams E., Willis F., Winter D., Wirsik M. M., Wishah B., Wong G., Wong W. J., Wong K., Wong K. -Y., Worku D., Wright E., Wright J., Wroe Wright O., Xenacki S., Xia W., Xu W., Xu Z., Yalcinkaya A., Yang W., Yang P. -C., Yanishev A., Yanzon De La Torre A., Yao H., Yaqoob E., Yen Ling Quake S., Yeo D., Yeom B., Yershov D., Yiasemidou M., Yildiz A., Yiu A., Yoav M., Yong E., Yoshimura R., Younis M. U., Younis Ringshawl Z., Youssef M., Yue Y., Yuen S., Yuldashev R., Yurttas C., Yves B., Zaborowski A., Zackeri R., Zafar A., Zahra W., Zaidi A., Zainudin S., Zakeri R., Zamora I., Zamora A. T., Zawistowski M., Zbikowska G., Zegers W., Zehra S., Zeyra A., Zhagniyev Z., Zhukova L. G., Zivanovic M., Zmuc J., Zope M., Zubayraeva A., and Zucker B.

Abstract

Background: Coronavirus disease 2019 (COVID-19) was declared a pandemic by the WHO on 11 March 2020 and global surgical practice was compromised. This Commission aimed to document and reflect on the changes seen in the surgical environment during the pandemic, by reviewing colleagues experiences and published evidence. Methods: In late 2020, BJS contacted colleagues across the global surgical community and asked them to describe how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had affected their practice. In addition to this, the Commission undertook a literature review on the impact of COVID-19 on surgery and perioperative care. A thematic analysis was performed to identify the issues most frequently encountered by the correspondents, as well as the solutions and ideas suggested to address them. Results: BJS received communications for this Commission from leading clinicians and academics across a variety of surgical specialties in every inhabited continent. The responses from all over the world provided insights into multiple facets of surgical practice from a governmental level to individual clinical practice and training. Conclusion: The COVID-19 pandemic has uncovered a variety of problems in healthcare systems, including negative impacts on surgical practice. Global surgical multidisciplinary teams are working collaboratively to address research questions about the future of surgery in the post-COVID-19 era. The COVID-19 pandemic is severely damaging surgical training. The establishment of a multidisciplinary ethics committee should be encouraged at all surgical oncology centres. Innovative leadership and collaboration is vital in the post-COVID-19 era.

Published
2021

10. Sur la dynamique des gaz dilués.

Author

BODINEAU, T., GALLAGHER, I., SAINT-RAYMOND, L., and SIMONELLA, S.

Abstract

Copyright of Gazette de la Société Mathématique de France is the property of Societe Mathematique de France and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2022

13. List of Contributors

Author

Conca, C., primary, Gallagher, I., additional, Ghrist, R., additional, Málek, J., additional, Pileckas, K., additional, Rajagopal, K.R., additional, Saint-Raymond, L., additional, Schochet, S., additional, Sell, G.R., additional, Seregin, G., additional, Serre, D., additional, and Vanninathan, M., additional

Published
2007
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22. The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells

Author

Blanco, F F, primary, Jimbo, M, additional, Wulfkuhle, J, additional, Gallagher, I, additional, Deng, J, additional, Enyenihi, L, additional, Meisner-Kober, N, additional, Londin, E, additional, Rigoutsos, I, additional, Sawicki, J A, additional, Risbud, M V, additional, Witkiewicz, A K, additional, McCue, P A, additional, Jiang, W, additional, Rui, H, additional, Yeo, C J, additional, Petricoin, E, additional, Winter, J M, additional, and Brody, J R, additional

Published
2015
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24. Mathematical geophysics. An introduction to rotating fluids and the Navier-Stokes equations

Author

Chemin, Jean-Yves, Desjardins, B., Gallagher, I., Grenier, Emmanuel, Ruprecht, Liliane, Laboratoire Jacques-Louis Lions (LJLL), and Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Physics::Fluid Dynamics
Abstract

Aimed at graduate students, researchers and academics in mathematics, engineering, oceanography, meteorology, and mechanics, this text provides a detailed introduction to the physical theory of rotating fluids, a significant part of geophysical fluid dynamics. The text is divided into four parts, with the first part providing the physical background of the geophysical models to be analyzed. Part two is devoted to a self contained proof of the existence of weak (or strong) solutions to the imcompressible Navier-Stokes equations. Part three deals with the rapidly rotating Navier-Stokes equations, first in the whole space, where dispersion effects are considered. The case where the domain has periodic boundary conditions is then analyzed, and finally rotating Navier-Stokes equations between two plates are studied, both in the case of periodic horizontal coordinated and those in R2. In Part IV, the stability of Ekman boundary layers and boundary layer effects in magnetohydrodynamics and quasigeostrophic equations are discussed. The boundary layers which appear near vertical walls are presented and formally linked with the classical Prandlt equations. Finally spherical layers are introduced, whose study is completely open.

Published
2006

33. Clinical trial in mentally retarded of chlorhexidine dental gel: bacteriology.

Author

Gallagher, I. H. C. and Cutress, T. W.

Subjects
*TEETH, *CHLORHEXIDINE, *DENTAL plaque, *BACTERIA, *MOUTH, *MICROBIOLOGY, *PEOPLE with intellectual disabilities, *PATIENTS
Abstract

A dental gel containing 1 % chlorhexidine was applied daily to the teeth of mentally retarded patients for a period of 6 months. Although possible antimicrobial effects were noted, the gel had no practical value in reducing the numbers of different plaque bacteria. It is suggested that the lack of effect may be due to changes in susceptibility of the oral flora surviving in the mouth, allowing subsequent recolonization of the teeth. [ABSTRACT FROM AUTHOR]

Published
1977
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41. The Ureolytic Microflora of Immature Dental Plaque Before and After Rinsing with a Urea-based Mineralizing Solution.

Author

GALLAGHER, I. H. C., PEARCE, E. I. F., and HANCOCK, E. M.

Subjects
DENTAL research, ORAL microbiology, DENTAL plaque, BACTERIA, BIOMINERALIZATION, UREA, PH effect, MOUTHWASHES
Abstract

Ureolytic bacteria were detected in the plaque flora of six subjects, and included members of the genera Actinomyces, Bifidobacterium, Staphylococcus, and Streptococcus. Proportions of these organisms did not change after subjects mouthrinsed thrice daily for four days with a plaque-mineralizing solution which contained urea and monofluorophosphate. The effectiveness of this rinse depends on the rapid metabolism of urea to alkali by plaque organisms, causing fluoridated apatite to precipitate in the matrix. Analysis of our data suggests that a numerically minor component of the flora, with a high turnover rate, is responsible for most of the ureolysis and the subsequent mineral precipitation. [ABSTRACT FROM AUTHOR]

Published
1984
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46. Gene-chip studies of adipogenesis-regulated microRNAs in mouse primary adipocytes and human obesity

Author

Gallagher Iain J, Petrovic Natasa, Gburcik Valentina, Keller Pernille, Nedergaard Jan, Cannon Barbara, and Timmons James A

Subjects
primary white and brown adipocytes, microRNAs, microarray, EXIQON, Affymetrix, Adipose tissue: adipocyte, transcriptome, Diseases of the endocrine glands. Clinical endocrinology, RC648-665
Abstract

Abstract Background Adipose tissue abundance relies partly on the factors that regulate adipogenesis, i.e. proliferation and differentiation of adipocytes. While components of the transcriptional program that initiates adipogenesis is well-known, the importance of microRNAs in adipogenesis is less well studied. We thus set out to investigate whether miRNAs would be actively modulated during adipogenesis and obesity. Methods Several models exist to study adipogenesis in vitro, of which the cell line 3T3-L1 is the most well known, albeit not the most physiologically appropriate. Thus, as an alternative, we produced EXIQON microarray of brown and white primary murine adipocytes (prior to and following differentiation) to yield global profiles of miRNAs. Results We found 65 miRNAs regulated during in vitro adipogenesis in primary adipocytes. We evaluated the similarity of our responses to those found in non-primary cell models, through literature data-mining. When comparing primary adipocyte profiles, with those of cell lines reported in the literature, we found a high degree of difference in 'adipogenesis' regulated miRNAs suggesting that the model systems may not be accurately representing adipogenesis. The expression of 10 adipogenesis-regulated miRNAs were studied using real-time qPCR and then we selected 5 miRNAs, that showed robust expression, were profiled in subcutaneous adipose tissue obtained from 20 humans with a range of body mass indices (BMI, range = 21-48, and all samples have U133+2 Affymetrix profiles provided). Of the miRNAs tested, mir-21 was robustly expressed in human adipose tissue and positively correlated with BMI (R2 = 0.49, p < 0.001). Conclusion In conclusion, we provide a preliminary analysis of miRNAs associated with primary cell in vitro adipogenesis and demonstrate that the inflammation-associated miRNA, mir-21 is up-regulated in subcutaneous adipose tissue in human obesity. Further, we provide a novel transcriptomics database of EXIQON and Affymetrix adipocyte profiles to facilitate data mining.

Published
2011
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49. PROBING THE STRUCTURE AND KINEMATICS OF THE TRANSITION LAYER BETWEEN THE MAGELLANIC STREAM AND THE HALO IN H I.

Author

Nigra, Lou, Stanimirović, Snežana, Gallagher I. I. I., John S., Wood, Kenneth, Nidever, David, and Majewski, Steven

Subjects
MAGELLANIC clouds, DWARF galaxies, GALACTIC halos, ASTROPHYSICS research, TURBULENCE
Abstract

The Magellanic Stream (MS) is a nearby laboratory for studying the fate of cool gas streams injected into a gaseous galactic halo. We investigate properties of the boundary layer between the cool MS gas and the hot Milky Way halo with 21 cm H I observations of a relatively isolated cloud having circular projection in the northern MS. Through averaging and modeling techniques, our observations, obtained with the Robert C. Byrd Green Bank Telescope, reach unprecedented 3σ sensitivity of ∼1 × 1017 cm–2, while retaining the telescope's 9.′1 resolution in the essential radial dimension. We find an envelope of diffuse neutral gas with FWHM of 60 km s–1, associated in velocity with the cloud core having FWHM of 20 km s–1, extending to 3.5 times the core radius with a neutral mass seven times that of the core. We show that the envelope is too extended to represent a conduction-dominated layer between the core and the halo. Its observed properties are better explained by a turbulent mixing layer driven by hydrodynamic instabilities. The fortuitous alignment of the NGC 7469 background source near the cloud center allows us to combine UV absorption and H I emission data to determine a core temperature of 8350 ± 350 K. We show that the H I column density and size of the core can be reproduced when a slightly larger cloud is exposed to Galactic and extragalactic background ionizing radiation. Cooling in the large diffuse turbulent mixing layer envelope extends the cloud lifetime by at least a factor of two relative to a simple hydrodynamic ablation case, suggesting that the cloud is likely to reach the Milky Way disk. [ABSTRACT FROM AUTHOR]

Published
2012
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50. A RARE EARLY-TYPE STAR REVEALED IN THE WING OF THE SMALL MAGELLANIC CLOUD.

Author

Evans, C. J., Hainich, R., Oskinova, L. M., Gallagher I. I. I., J. S., Chu, Y. -H, Gruendl, R. A., Hamann, W. -R, Hénault-Brunet, V., and Todt, H.

Subjects
NEBULAE, SMALL magellanic cloud, OPTICAL spectroscopy, TEMPERATURE of stars, STELLAR mass, STAR clusters
Abstract

Sk 183 is the visually brightest star in the N90 nebula, a young star-forming region in the Wing of the Small Magellanic Cloud (SMC). We present new optical spectroscopy from the Very Large Telescope which reveals Sk 183 to be one of the most massive O-type stars in the SMC. Classified as an O3-type dwarf on the basis of its nitrogen spectrum, the star also displays broadened He I absorption, which suggests a later type. We propose that Sk 183 has a composite spectrum and that it is similar to another star in the SMC, MPG 324. This brings the number of rare O2- and O3-type stars known in the whole of the SMC to a mere four. We estimate physical parameters for Sk 183 from analysis of its spectrum. For a single-star model, we estimate an effective temperature of 46 ± 2 kK, a low mass-loss rate of ∼10–7M☼ yr–1, and a spectroscopic mass of 46+9–8M☼ (for an adopted distance modulus of 18.7 mag to the young population in the SMC Wing). An illustrative binary model requires a slightly hotter temperature (∼47.5 kK) for the primary component. In either scenario, Sk 183 is the earliest-type star known in N90 and will therefore be the dominant source of hydrogen-ionizing photons. This suggests Sk 183 is the primary influence on the star formation along the inner edge of the nebula. [ABSTRACT FROM AUTHOR]

Published
2012
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