Search

Your search keyword '"Gallardo, David"' showing total 454 results
Start Over Author "Gallardo, David"
454 results on '"Gallardo, David"'

4. Context-Aware Personality Inference in Dyadic Scenarios: Introducing the UDIVA Dataset

Author

Palmero, Cristina, Selva, Javier, Smeureanu, Sorina, Junior, Julio C. S. Jacques, Clapés, Albert, Moseguí, Alexa, Zhang, Zejian, Gallardo, David, Guilera, Georgina, Leiva, David, and Escalera, Sergio

Subjects
Computer Science - Computer Vision and Pattern Recognition, Computer Science - Artificial Intelligence, Computer Science - Machine Learning
Abstract

This paper introduces UDIVA, a new non-acted dataset of face-to-face dyadic interactions, where interlocutors perform competitive and collaborative tasks with different behavior elicitation and cognitive workload. The dataset consists of 90.5 hours of dyadic interactions among 147 participants distributed in 188 sessions, recorded using multiple audiovisual and physiological sensors. Currently, it includes sociodemographic, self- and peer-reported personality, internal state, and relationship profiling from participants. As an initial analysis on UDIVA, we propose a transformer-based method for self-reported personality inference in dyadic scenarios, which uses audiovisual data and different sources of context from both interlocutors to regress a target person's personality traits. Preliminary results from an incremental study show consistent improvements when using all available context information., Comment: Accepted to the 11th International Workshop on Human Behavior Understanding workshop at Winter Conference on Applications of Computer Vision 2021

Published
2020

6. Front-line fludarabine-cyclophosphamide-rituximab (FCR) in 110 patients with chronic lymphocytic leukaemia (CLL): real-life experience with long-term outcomes, toxicities and responses to second-line therapies

Author

Oliveira, Ana C., Roncero, Josep Maria, Ferrá, Christelle, Do Nascimento, Janilson, Rodriguez-Luaces, Marta, Encuentra, Maite, Domingo-Domenech, Eva, López, Patricia, Gallardo, David, Ribera, Josep Maria, Sarrá, Josep, Sureda, Anna, and González-Barca, Eva

Published
2023
Full Text
View/download PDF

7. Risk prediction of CMV reactivation after allogeneic stem cell transplantation using five non-HLA immunogenetic polymorphisms

Author

Vallejo, Miren, Muñiz, Paula, Kwon, Mi, Solán, Laura, Bailén, Rebeca, Carbonell, Diego, Chicano, María, Suárez-González, Julia, Catalán, Pilar, Bellón, José María, Triviño, Juan Carlos, Dorado, Nieves, Gallardo, David, Díez-Martín, José Luis, Ramírez, Natalia, Martínez-Laperche, Carolina, and Buño, Ismael

Published
2022
Full Text
View/download PDF

8. Surgery of the Infratemporal Fossa and Parapharyngeal Space

Author

Guinto, Gerardo, Hernández, Eli, Gallardo, David, Aréchiga, Norma, Gallegos, Francisco, Zepeda, Erick, Abdo, Miguel, Correa-Correa, Víctor, Monroy-Sosa, Alejandro, editor, Chakravarthi, Srikant S., editor, de la Garza-Salazar, Jaime G., editor, Meneses Garcia, Abelardo, editor, and Kassam, Amin B., editor

Published
2021
Full Text
View/download PDF

9. European LeukemiaNet 2017 risk stratification for acute myeloid leukemia: validation in a risk-adapted protocol

Author

Bataller, Alex, Garrido, Ana, Guijarro, Francesca, Oñate, Guadalupe, Diaz-Beyá, Marina, Arnan, Montserrat, Tormo, Mar, Vives, Susana, de Llano, María Paz Queipo, Coll, Rosa, Gallardo, David, Vall-Llovera, Ferran, Escoda, Lourdes, Garcia-Guiñon, Antonio, Salamero, Olga, Sampol, Antònia, Merchan, Brayan M., Bargay, Joan, Castaño-Díez, Sandra, Esteban, Daniel, Oliver-Caldés, Aina, Rivero, Andrea, Mozas, Pablo, López-Guerra, Mònica, Pratcorona, Marta, Zamora, Lurdes, Costa, Dolors, Rozman, Maria, Nomdedéu, Josep F., Colomer, Dolors, Brunet, Salut, Sierra, Jorge, and Esteve, Jordi

Published
2022
Full Text
View/download PDF

10. Grado de dependencia basal en actividades básicas e instrumentales de la vida diaria como factor predictivo de supervivencia de los pacientes dados de alta de la Unidad de Cuidados Intensivos de un hospital público de la ciudad de Santiago de Chile, en un período de 5 años.

Author

Miguel Arancibia, José, Ebner, Matías, Gallardo, David, Aravena, Florencia, Muñoz, Álex, Hurtado, Javier, Gómez, Carlos, Caniguante, Guillermina, Bozzano, Gala, Barrios, Paulina, Bustamante, Carmen, Gallegos, Sebastián, and Eduardo Sánchez, Juan

Subjects
PUBLIC hospitals, HOSPITAL care, CATASTROPHIC illness, DISCHARGE planning, DESCRIPTIVE statistics, LONGITUDINAL method, INTENSIVE care units, SURVIVAL analysis (Biometry), DEPENDENCY (Psychology)
Abstract

Copyright of Revista Argentina de Terapia Intensiva is the property of Sociedad Argentina de Terapia Intensiva (SATI) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024

11. Effect of NK cell receptor genetic variation on allogeneic stem cell transplantation outcome and in vitro NK cell cytotoxicity

Author

Nihtilä, Julia, primary, Penna, Leena, additional, Salmenniemi, Urpu, additional, Itälä-Remes, Maija, additional, Crossland, Rachel E, additional, Gallardo, David, additional, Bogunia-Kubik, Katarzyna, additional, Lacina, Piotr, additional, Bieniaszewska, Maria, additional, Giebel, Sebastian, additional, Karjalainen, Katariina, additional, Jahan, Farhana, additional, Kerkelä, Erja, additional, Hyvärinen, Kati, additional, Koskela, Satu, additional, Ritari, Jarmo, additional, and Partanen, Jukka, additional

Published
2024
Full Text
View/download PDF

12. CD200 genotype is associated with clinical outcome of patients with multiple myeloma

Author

Gonzalez-Montes, Yolanda, primary, Osca-Gelis, Gemma, additional, Rodriguez-Romanos, Rocío, additional, Villavicencio, Alicia, additional, González-Bártulos, Marta, additional, Llopis, Francesca, additional, Clapes, Victòria, additional, Oriol, Albert, additional, Sureda, Anna, additional, Escoda, Lourdes, additional, Sarrà, Josep, additional, Garzó, Ana, additional, Lloveras, Natàlia, additional, Gómez, Beatriz, additional, Granada, Isabel, additional, and Gallardo, David, additional

Published
2024
Full Text
View/download PDF

13. Mobilization of Hematopoietic Stem Cells into Peripheral Blood for Autologous Transplantation Seems Less Efficacious in Poor Mobilizers with the Use of a Biosimilar of Filgrastim and Plerixafor: A Retrospective Comparative Analysis

Author

Parody, Rocío, Sánchez-Ortega, Isabel, Ferrá, Christelle, Guardia, Ramon, Talarn, Carme, Encuentra, Maite, Fort, Eduard, López, David, Morgades, Mireia, Alonso, Eva, Ortega, Sandra, Sarrá, Josep, Gallardo, David, Ribera, Josep M., and Sureda, Anna

Published
2020
Full Text
View/download PDF

17. A novel predictive approach for GVHD after allogeneic SCT based on clinical variables and cytokine gene polymorphisms

Author

Martínez-Laperche, Carolina, Buces, Elena, Aguilera-Morillo, M. Carmen, Picornell, Antoni, González-Rivera, Milagros, Lillo, Rosa, Santos, Nazly, Martín-Antonio, Beatriz, Guillem, Vicent, Nieto, José B., González, Marcos, de la Cámara, Rafael, Brunet, Salut, Jiménez-Velasco, Antonio, Espigado, Ildefonso, Vallejo, Carlos, Sampol, Antonia, Bellón, José María, Serrano, David, Kwon, Mi, Gayoso, Jorge, Balsalobre, Pascual, Urbano-Izpizua, Álvaro, Solano, Carlos, Gallardo, David, Díez-Martín, José Luis, Romo, Juan, and Buño, Ismael

Published
2018
Full Text
View/download PDF

20. Donor CTLA-4 Genotype Modulates the Immune Response to Minor Histocompatibility Antigen Mismatches

Author

Gallardo, David, Bosch-Vizcaya, Anna, Rodríguez-Romanos, Rocío, Santos, Nazly, Buño, Ismael, de la Cámara, Rafael, Brunet, Salut, Jiménez-Velasco, Antonio, González, Marcos, Nieto, Jose B., Martínez-Laperche, Carolina, Vallejo, Carlos, Ferrá, Christelle, Sampol, Antònia, López-Jiménez, Javier, Pérez-Simón, Jose A., Martínez, Carmen, and Díez, Jose L.

Published
2017
Full Text
View/download PDF

21. PD-1 genotype of the donor is associated with acute graft-versus-host disease after HLA-identical sibling donor stem cell transplantation

Author

Santos, Nazly, Rodríguez-Romanos, Rocío, de la Cámara, Rafael, Brunet, Salut, Nieto, Jose B., Buño, Ismael, Martínez, Carmen, Jiménez-Velasco, Antonio, Vallejo, Carlos, González, Marcos, Solano, Carlos, Ferrá, Christelle, Sampol, Antonia, Pérez-Simón, Jose A., López-Jiménez, Javier, Díez, José L., Gallardo, David, and On behalf of the GvHD/Immunotherapy Working Party of the Spanish Group of Hematopoietic Transplant (GETH)

Published
2018
Full Text
View/download PDF

23. Genetic variants of CTLA4 are associated with clinical outcome of patients with multiple myeloma

Author

Gonzalez-Montes, Yolanda, primary, Rodriguez-Romanos, Rocío, additional, Villavicencio, Alicia, additional, Osca-Gelis, Gemma, additional, González-Bártulos, Marta, additional, Llopis, Francesca, additional, Clapes, Victòria, additional, Oriol, Albert, additional, Sureda, Anna, additional, Escoda, Lourdes, additional, Sarrà, Josep, additional, Garzó, Ana, additional, Lloveras, Natàlia, additional, Díez, Isabel, additional, Granada, Isabel, additional, and Gallardo, David, additional

Published
2023
Full Text
View/download PDF

24. LAG3 genotype of the donor and clinical outcome after allogeneic transplantation from HLA-identical sibling donors

Author

Universidad de Sevilla. Instituto de Biomedicina de Sevilla (IBIS), Universidad de Sevilla. Departamento de Medicina, Instituto de Salud Carlos III, Cruz, David, Rodríguez-Romanos, Rocío, González-Bartulos, Marta, García-Cadenas, Irene, de la Cámara, Rafael, Heras, Inmaculada, Pérez Simón, José Antonio, Gallardo, David, Universidad de Sevilla. Instituto de Biomedicina de Sevilla (IBIS), Universidad de Sevilla. Departamento de Medicina, Instituto de Salud Carlos III, Cruz, David, Rodríguez-Romanos, Rocío, González-Bartulos, Marta, García-Cadenas, Irene, de la Cámara, Rafael, Heras, Inmaculada, Pérez Simón, José Antonio, and Gallardo, David

Abstract

Introduction: The association of polymorphisms in molecules involved in the immune response (checkpoint inhibitors) with the clinical outcome after allogeneic transplantation (alloHSCT) has been described. Lymphocyte Activation 3 (LAG3) is a surface protein that plays a regulatory role in immunity as an inhibitory immune checkpoint molecule. Methods: To determine its role in the alloHSCT setting, we analyzed 797 patients transplanted from HLA-identical sibling donors. The LAG3 rs870849 C>T polymorphism was genotyped in donors. Results: We detected a higher incidence of severe acute GVHD in patients transplanted from donors with TT genotype (p: 0.047, HR 1.64; 95% CI 1.01 – 2.67). Overall survival (OS) was worse for patients transplanted from donors with the rs870849 CT/TT genotype (0.020; HR, 1.44; 95% CI 1.06 – 1.96), as well as disease-free survival (DFS) (p: 0.002; HR 1.58, 95%CI: 1.18 – 2.14) and transplantrelated mortality (TRM) (p< 0.001; HR: 1.88, 95% CI 1.29 – 2.74). When combining the LAG3 rs870849 and the PDCD1 rs36084323 genotypes of the donor, three genetic groups were well defined, allowing a good stratification of the risk of acute GVHD, TRM, OS and DFS. Discussion: We conclude that the LAG3 genotype of the donor may be considered in donors’ selection. As this selection may be limited in the HLA-identical sibling donor scenario, further studies exploring the impact of LAG3 genotype of the donor in unrelated transplantation are warranted

Published
2023

25. LAG3 genotype of the donor and clinical outcome after allogeneic transplantation from HLA-identical sibling donors

Author

Instituto de Salud Carlos III, European Commission, Cruz, David, Rodríguez-Romanos, Rocío, González-Bartulos, Marta, García-Cadenas, Irene, Cámara, Rafael de la, Heras, Inmaculada, Buño, Ismael, Santos, Nazly, Lloveras, Natàlia, Velarde, Pilar, Tuset, Esperanza, Martínez, Carmen, González, Marcos, Sanz, Guillermo F., Ferrá, Christelle, Sampol, Antonia, Coll, Rosa, Pérez-Simón, José A., López-Jiménez, Javier, Jurado, Manuel, Gallardo, David, GvHD/Immunotherapy Working Party of the Spanish Group of Hematopoietic Transplant (GETH), Instituto de Salud Carlos III, European Commission, Cruz, David, Rodríguez-Romanos, Rocío, González-Bartulos, Marta, García-Cadenas, Irene, Cámara, Rafael de la, Heras, Inmaculada, Buño, Ismael, Santos, Nazly, Lloveras, Natàlia, Velarde, Pilar, Tuset, Esperanza, Martínez, Carmen, González, Marcos, Sanz, Guillermo F., Ferrá, Christelle, Sampol, Antonia, Coll, Rosa, Pérez-Simón, José A., López-Jiménez, Javier, Jurado, Manuel, Gallardo, David, and GvHD/Immunotherapy Working Party of the Spanish Group of Hematopoietic Transplant (GETH)

Abstract

Introduction: The association of polymorphisms in molecules involved in the immune response (checkpoint inhibitors) with the clinical outcome after allogeneic transplantation (alloHSCT) has been described. Lymphocyte Activation 3 (LAG3) is a surface protein that plays a regulatory role in immunity as an inhibitory immune checkpoint molecule., Methods: To determine its role in the alloHSCT setting, we analyzed 797 patients transplanted from HLA-identical sibling donors. The LAG3 rs870849 C>T polymorphism was genotyped in donors., Results: We detected a higher incidence of severe acute GVHD in patients transplanted from donors with TT genotype (p: 0.047, HR 1.64; 95% CI 1.01 – 2.67). Overall survival (OS) was worse for patients transplanted from donors with the rs870849 CT/TT genotype (0.020; HR, 1.44; 95% CI 1.06 – 1.96), as well as disease-free survival (DFS) (p: 0.002; HR 1.58, 95%CI: 1.18 – 2.14) and transplant-related mortality (TRM) (p< 0.001; HR: 1.88, 95% CI 1.29 – 2.74). When combining the LAG3 rs870849 and the PDCD1 rs36084323 genotypes of the donor, three genetic groups were well defined, allowing a good stratification of the risk of acute GVHD, TRM, OS and DFS., Discussion: We conclude that the LAG3 genotype of the donor may be considered in donors’ selection. As this selection may be limited in the HLA-identical sibling donor scenario, further studies exploring the impact of LAG3 genotype of the donor in unrelated transplantation are warranted.

Published
2023

26. Awoo the Penguin

Author

Videla-Rodríguez, José-Juan, Universidade da Coruña. Facultade de Ciencias da comunicación, Ariyawatgul Alcañiz, Lalita, Muradás Gallardo, David, De Blas Vences, Jorge, Videla-Rodríguez, José-Juan, Universidade da Coruña. Facultade de Ciencias da comunicación, Ariyawatgul Alcañiz, Lalita, Muradás Gallardo, David, and De Blas Vences, Jorge

Abstract

[Resumen] Desarrollo del primer episodio de la serie de Awoo the Penguin, en el que los protagonistas, Awoo y Flake, se conocen. Juntos harán nuevos amigos y vivirán miles de aventuras, que toda la familia podrá disfrutar a través de Youtube.

Published
2023

27. LAG3 genotype of the donor and clinical outcome after allogeneic transplantation from HLA-identical sibling donors

Author

Cruz, David, primary, Rodríguez-Romanos, Rocío, additional, González-Bartulos, Marta, additional, García-Cadenas, Irene, additional, de la Cámara, Rafael, additional, Heras, Inmaculada, additional, Buño, Ismael, additional, Santos, Nazly, additional, Lloveras, Natàlia, additional, Velarde, Pilar, additional, Tuset, Esperanza, additional, Martínez, Carmen, additional, González, Marcos, additional, Sanz, Guillermo F., additional, Ferrá, Christelle, additional, Sampol, Antonia, additional, Coll, Rosa, additional, Pérez-Simón, Jose A., additional, López-Jiménez, Javier, additional, Jurado, Manuel, additional, and Gallardo, David, additional

Published
2023
Full Text
View/download PDF

28. Serum Galactomannan Versus a Combination of Galactomannan and Polymerase Chain Reaction–Based Aspergillus DNA Detection for Early Therapy of Invasive Aspergillosis in High-Risk Hematological Patients: A Randomized Controlled Trial

Author

PCRAGA Study Group, the Spanish Stem Cell Transplantation Group, the Study Group of Medical Mycology of the Spanish Society of Clinical Microbiology and Infectious Diseases, and the Spanish Network for Research in Infectious Diseases, Aguado, José María, Vázquez, Lourdes, Fernández-Ruiz, Mario, Villaescusa, Teresa, Ruiz-Camps, Isabel, Barba, Pere, Silva, Jose T., Batlle, Montserrat, Solano, Carlos, Gallardo, David, Heras, Inmaculada, Polo, Marta, Varela, Rosario, Vallejo, Carlos, Olave, Teresa, López-Jiménez, Javier, Rovira, Montserrat, Parody, Rocío, and Cuenca-Estrella, Manuel

Published
2015

29. Front-line fludarabine-cyclophosphamide-rituximab (FCR) in 110 patients with chronic lymphocytic leukaemia (CLL): real-life experience with long-term outcomes, toxicities and responses to second-line therapies

Author

Oliveira, Ana C., primary, Roncero, Josep Maria, additional, Ferrá, Christelle, additional, Do Nascimento, Janilson, additional, Rodriguez-Luaces, Marta, additional, Encuentra, Maite, additional, Domingo-Domenech, Eva, additional, López, Patricia, additional, Gallardo, David, additional, Ribera, Josep Maria, additional, Sarrá, Josep, additional, Sureda, Anna, additional, and González-Barca, Eva, additional

Published
2022
Full Text
View/download PDF

31. Determinacions del perfil genètic de les malalties neoplàstiques hematològiques

Author

Abrisqueta Costa, Pablo, Bellosillo, Beatriu, Bosch Albareda, Francesc, Briones, Javier, Climent, Fina, Colomer, Dolors, Esteve Reyner, Jordi, Gallardo, David, Garcia Cerecedo, Tomas, Genescà, Eulàlia, Lopez Guillermo, Armando, Nomdedeu, Josep, Pratcorona, Marta, Ribera, Jordi, Ribera, Jose-Maria, Salar, Antonio, Tazon-Vega, Barbara, Valcarcel, David, Zamora, Lurdes, [Abrisqueta P, Bosch F, Tazon B, Valcárcel D] Hospital Universitari Vall d’Hebron, Barcelona, Spain. [Bellosillo B, Salar A] Hospital del Mar, Barcelona, Spain. [Briones J, Nomdedeu J, Pratcorona M] Hospital de la Santa Creu Sant Pau, Barcelona, Spain. [Climent F] Hospital Universitari de Bellvitge, Hospitalet de Llobregat, Spain. [Colomer D, Esteve J, Lopez A] Hospital Clínic i Provincial de Barcelona, Barcelona, Spain. [Gallardo D] Institut d’Oncologia Mèdica (ICO), Hospital Universitari de Girona Doctor Josep Trueta, Girona, Spain. [Garcia T] Hospital Universitari Arnau de Vilanova, Lleida, Spain. [Genescà E] Institut de Recerca contra la Leucèmia Josep Carreras, Barcelona, Spain. [Ribera JM, Zamora L] Institut d’Oncologia Mèdica (ICO), Hospital Universitari Germans Trias i Pujol, Badalona, Spain, and Departament de Salut

Subjects
Hematologia oncològica - Aspectes genètics, profesiones sanitarias::medicina::medicina interna::oncología médica [DISCIPLINAS Y OCUPACIONES], fenómenos genéticos::trasfondo genético::perfil genético [FENÓMENOS Y PROCESOS], Genetic Phenomena::Genetic Background::Genetic Profile [PHENOMENA AND PROCESSES], Health Occupations::Medicine::Internal Medicine::Medical Oncology [DISCIPLINES AND OCCUPATIONS], profesiones sanitarias::medicina::medicina interna::hematología [DISCIPLINAS Y OCUPACIONES], Tumors, Health Occupations::Medicine::Internal Medicine::Hematology [DISCIPLINES AND OCCUPATIONS]
Abstract

Malalties neoplàstiques hematològiques; Perfil genètic; Precisió Enfermedades neoplásticas hematológicas; Perfil genético; Precisión Hematological neoplastic diseases; Genetic profile; Accuracy La patologia hematooncològica s’ha dividit en tres grups: limfoide, mieloide i leucèmia aguda limfoblàstica. S’ha definit la llista de gens adequada per a cada patologia i tots ells han estat seleccionats atenent a: La seva utilitat diagnòstica i de diagnòstic diferencial amb altres entitats i que, per tant, permetin a l’equip diagnòstic (hematòlegs, patòlegs o biòlegs) realitzar un diagnòstic ben fet. La seva utilitat pronòstica i predictiva, sempre que això comporti un canvi d’actitud terapèutica. Per exemple, indicació de trasplantament de progenitors o altres teràpies cel·lulars, canvi en el seguiment i canvi en el tipus de tractament. La seva utilitat terapèutica per a la indicació de l’ús de fàrmacs diana.

Published
2022

32. Association between gene polymorphisms in the cyclophosphamide metabolism pathway with complications after haploidentical hematopoietic stem cell transplantation

Author

Muñiz, Paula, primary, Andrés-Zayas, Cristina, additional, Carbonell, Diego, additional, Chicano, María, additional, Bailén, Rebeca, additional, Oarbeascoa, Gillen, additional, Suárez-González, Julia, additional, Gómez Centurión, Ignacio, additional, Dorado, Nieves, additional, Gallardo, David, additional, Anguita, Javier, additional, Kwon, Mi, additional, Díez-Martín, Jose L., additional, Martínez-Laperche, Carolina, additional, and Buño, Ismael, additional

Published
2022
Full Text
View/download PDF

33. Commissioning, on sky performance and first operations of JPCam, a 1.2 Gpixel camera for the wide-field 2.6m Javalambre Survey Telescope

Author

Marín-Franch, Antonio, primary, Rueda-Teruel, Sergio, additional, López-Alegre, Guillermo, additional, Íñiguez, César, additional, Vázquez Ramió, Héctor, additional, Ederoclite, Alessandro, additional, Bello Ferrer, Rafael, additional, Royo-Navarro, Miriam, additional, Casino-Martín, José María, additional, Lozano-Pérez, David, additional, Molina-Ibáñez, Enrique Luís, additional, Rueda-Teruel, Fernando, additional, Yanes-Díaz, Axel, additional, del Pino, Andrés, additional, López-Sanjuan, Carlos, additional, Cenarro Lagunas, Andrés Javier, additional, Cristóbal-Hornillos, David, additional, Hernán-Caballero, Antonio, additional, Moles, Mariano, additional, Varela, Jesús, additional, Bielsa, Samuel, additional, Chueca, Sergio, additional, Domínguez, Mikel, additional, Garcés, David, additional, Martínez, Nuria, additional, Muñoz-Maudos, Jorge, additional, Rueda, Héctor, additional, Soriano, Ildefonso, additional, Castillo, Juan, additional, Civera, Tamara, additional, Hernández, Javier, additional, López-Sainz, Ángel, additional, Moreno-Signes, Alberto, additional, Muniesa-Gallardo, David José, additional, Taylor, Keith, additional, Santoro, Fernando, additional, Cepa Nogue, Jordi, additional, Fermino, Carlos, additional, Bastable, Matthew, additional, Haddow, Gordon, additional, Palmer, Ian, additional, Robbins, Mark, additional, Simpson, Chris, additional, Spatola, Antonino, additional, Sweeney, Helen, additional, Tatard, Christophe, additional, Watkins, Marc, additional, Brauneck, Ulf, additional, Casalta, Joan Manel, additional, Abramo, Raul, additional, Alcaniz, Jailson, additional, Benítez, Narciso, additional, Bonoli, Silvia, additional, Carneiro, Saulo, additional, Dupke, Renato, additional, Mendes de Oliveira, Claudia, additional, Sodré, Laerte, additional, and Vílchez, José Manuel, additional

Published
2022
Full Text
View/download PDF

35. Hybrid Glide-Symmetric Unit Cell for Leakage Reduction in Millimeter-Wave PCB Interconnections to Waveguide Components

Author

Gonzalez-Gallardo, David, Algaba-Brazalez, Astrid, Manholm, Lars, Johansson, Martin, Quevedo-Teruel, Oscar, Gonzalez-Gallardo, David, Algaba-Brazalez, Astrid, Manholm, Lars, Johansson, Martin, and Quevedo-Teruel, Oscar

Abstract

In this article, we propose a hybrid glide-symmetric metasurface which presents an electromagnetic bandgap (ERG) behavior at the Ka-band. The innovative part of this work is the hybrid nature of the periodic structure, which is implemented with holes on two different technologies: printed circuit board (PCB) and metallic waveguide. These holes avoid propagation in an undesired parallel plate created between a PCB and a metallic waveguide. To demonstrate the potential of this concept, a hybrid glide-symmetric configuration was placed surrounding a PCB-waveguide transition at the Ka-band to reduce the leakage created by undesired air gaps. A prototype was manufactured and measured to corroborate the effectiveness of this technique to reduce losses and crosstalk., QC 20220523

Published
2022
Full Text
View/download PDF

38. Donor CTLA-4 Genotype Influences Clinical Outcome after T Cell-Depleted Allogeneic Hematopoietic Stem Cell Transplantation from HLA-Identical Sibling Donors

Author

Bosch-Vizcaya, Anna, Pérez-García, Arianne, Brunet, Salut, Solano, Carlos, Buño, Ismael, Guillem, Vicent, Martínez-Laperche, Carolina, Sanz, Guillermo, Barrenetxea, Cristina, Martínez, Carmen, Tuset, Esperanza, Lloveras, Natàlia, Coll, Rosa, Guardia, Ramon, González, Yolanda, Roncero, Josep M., Bustins, Anna, Gardella, Santiago, Fernández, Cristalina, Buch, Joan, and Gallardo, David

Published
2012
Full Text
View/download PDF

40. Costs and benefits of automation for astronomical facilities

Author

Axel Yanes Díaz, Sergio Rueda-Teruel, Rafael Bello, David Lozano, Miriam Royo Navarro, Tamara Civera, Mikel Domínguez Martínez, Nuria Martínez Olivar, Sergio Chueca, Cesar Iñiguez García, Antonio Marín Franch, Fernando Rueda-Teruel, Guillermo López-Alegre, Samuel Bielsa de Toledo, Jorge Muñoz Maudos, Hector Rueda Asensio, Alejandro Muñoz Teruel, David Garcés Cubel, Ildefonso Soriano Laguía, María Almarcegui Gracia, Javier Cenarro Lagunas, Mariano Moles Villamate, David Cristobal Hornillos, Jesús Varela López, Alessandro Ederoclite, Héctor Vázquez Ramió, Miguel Chioare Díaz Martín, Ramón Iglesias Marzoa, Juan Castillo, Angel López-Sainz, Javier Hernández Fuertes, Muniesa-Gallardo David, Alberto Moreno Signes, Antonio Hernán Caballero, Carlos López Sanjuan, Andrés Del Pino, Akhlaghi Mohammad, Irene Pintos Castro, Juan Antonio Fernández Ontiveros, Fabiola Carolina Hernández Pérez, Stylianos Stylianos, Raul Infante, Teet Kuutma, Alejandro Lumbreras, Natalio Maicas, Jose Luis Lamadrid, Fátima lópez Martinez, Francisco José Galindo Guil, Elvis Lacruz Calderón, Luisa Valdivielso Casas, Maribel Aguilar Martín, Sepideh Eskandarlou, Alejandro Javier Domínguez Fernández, Francisco Arizo Borillo, Silvia Vaquero Valer, Inés Muñoz Igado, María Teresa Alegre Sánchez, Gema María Julián Caballero de España, Alicia Romero, and David Casinos Cardo

Subjects
FOS: Physical sciences, Astrophysics - Instrumentation and Methods for Astrophysics, Instrumentation and Methods for Astrophysics (astro-ph.IM)
Abstract

The Observatorio Astrof\'isico de Javalambre (OAJ{\dag}1) in Spain is a young astronomical facility, conceived and developed from the beginning as a fully automated observatory with the main goal of optimizing the processes in the scientific and general operation of the Observatory. The OAJ has been particularly conceived for carrying out large sky surveys with two unprecedented telescopes of unusually large fields of view (FoV): the JST/T250, a 2.55m telescope of 3deg field of view, and the JAST/T80, an 83cm telescope of 2deg field of view. The most immediate objective of the two telescopes for the next years is carrying out two unique photometric surveys of several thousands square degrees, J-PAS{\dag}2 and J-PLUS{\dag}3, each of them with a wide range of scientific applications, like e.g. large structure cosmology and Dark Energy, galaxy evolution, supernovae, Milky Way structure, exoplanets, among many others. To do that, JST and JAST are equipped with panoramic cameras under development within the J-PAS collaboration, JPCam and T80Cam respectively, which make use of large format (~ 10k x 10k) CCDs covering the entire focal plane. This paper describes in detail, from operations point of view, a comparison between the detailed cost of the global automation of the Observatory and the standard automation cost for astronomical facilities, in reference to the total investment and highlighting all benefits obtained from this approach and difficulties encountered. The paper also describes the engineering development of the overall facilities and infrastructures for the fully automated observatory and a global overview of current status, pinpointing lessons learned in order to boost observatory operations performance, achieving scientific targets, maintaining quality requirements, but also minimizing operation cost and human resources., Comment: Global Observatory Control System GOCS

Published
2022
Full Text
View/download PDF

43. Genetic characterization of acute myeloid leukemia patients with mutations in IDH1/2 genes

Author

Acha, Pamela, Hoyos, Montserrat, Pratcorona, Marta, Fuster-Tormo, Francisco, Palomo, Laura, Ortega, Esther, Zamora, Lurdes, Vives, Susana, Granada, Isabel, Montoro, Julia, Garcia, Antoni, Arnan, Montserrat, Cervera, Marta, Canet, Marta, Gallardo, David, Arenillas, Leonor, Esteve, Jordi, Baragay, Joan, Salamero, Olga, Motlló, Cristina, Ortín, Xavier, Sierra, Jordi, and Solé, Francesc

Published
2021
Full Text
View/download PDF

46. Ubtf tandem Duplications Define a Novel Subtype of Acute Myeloid Leukemia Associated with Younger Age, WT1 Mutations and HOXA9 Marked Overexpression

Author

Castellet, Helena, Ramil López, Guillermo, Garrido, Ana, Artigas-Baleri, Alícia, Pratcorona, Marta, Salamero, Olga, Cortés-Bullich, Albert, Vives, Susana, Tormo, Mar, Mascaro Riera, Martin, Gallardo, David, Marti Tutusaus, Josep Maria, Garcia, Antonio, Sierra, Jorge, Esteve, Jordi, and Nomdedeu, Josep

Published
2023
Full Text
View/download PDF

47. Mobilization of Hematopoietic Stem Cells into Peripheral Blood for Autologous Transplantation Seems Less Efficacious in Poor Mobilizers with the Use of a Biosimilar of Filgrastim and Plerixafor: A Retrospective Comparative Analysis

Author

Parody Porras, Rocío, Sánchez Ortega, Isabel, Ferrá, Christelle, Guardia, Ramon, Talarn, Carme, Encuentra, Maite, Fort, Eduard, López, David, Morgades, Mireia, Alonso, Eva, Ortega, Sandra, Sarrá, Josep, Gallardo, David, Ribera, Josep M., Sureda, Anna, and Universitat Autònoma de Barcelona

Subjects
Oncology, medicine.medical_specialty, medicine.drug_class, Pharmaceutical biotechnology, Stem cells, Filgrastim, Neutropenia, Immunostimulant, Internal medicine, Medicine, Autologous transplantation, RC254-282, Biosimilars, Mobilization, business.industry, Brief Report, Plerixafor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Combination chemotherapy, medicine.disease, Stem cell mobilization, Stem cell, business, Cèl·lules mare, Biotecnologia farmacèutica, medicine.drug
Abstract

Introduction Biosimilars of granulocyte colony-stimulating factors (G-CSF) have shown similar efficacy to originator filgrastim (Neupogen® [NEU]; Amgen Inc.) as prophylaxis in neutropenia and in the mobilization of stem cells in patients receiving combination chemotherapy with G-CSF. Methods This was a retrospective study in which the characteristics of stem cell mobilization treated with a G-CSF alone were compared in 216 patients and 56 donors. The two G-CSF compared were NEU and the biosimilar filgrastim Zarzio® (Sandoz GmbH) (referred to hereafter as BIO). Primary objectives were mobilization rate (minimum of 10 × 103/ml CD34+ on day 4 of treatment [day +4]) and use of the immunostimulant plerixafor (PLEX) in each group. Results The general characteristics of the patients receiving NEU (n = 138) and those receiving BIO (n = 78) did not differ significantly. PLEX was used in 24% of BIO patients and in 25.7% of NEU patients. The median CD34+ cell count on day +4 was significantly lower in BIO patients who needed PLEX than in those who did not (2.4 vs. 4.8 × 103/ml; p = 0.002), as was the final CD34+ cell count (2.5 vs. 3.3 × 106/kg; p 0.03). Mobilization failure rate was higher in the BIO group than in the NEU group (20 vs. 0%; p = 0.01). With respect to donors, more than one apheresis was needed in three BIO donors, one of them with PLEX. The use of BIO was the only risk factor for mobilization failure in patients who needed PLEX (hazard ratio 10.3; 95% confidence interval 1.3–77.8). Conclusion The study revealed that BIO had a lower efficacy for stem cell mobilization when the only treatment was G-CSF, especially in poor mobilizers needing PLEX.

Published
2020

48. CTLA-4 polymorphisms and clinical outcome after allogeneic stem cell transplantation from HLA-identical sibling donors.

Author

Pérez-García, Arianne, De la Cámara, Rafael, Román-Gómez, Jose, Jiménez-Velasco, Antonio, Encuentra, Maite, Nieto, Jose B., de la Rubia, Javier, Urbano-Ispizúa, Alvaro, Brunet, Salut, Iriondo, Arturo, González, Marcos, Serrano, David, Espigado, Ildefonso, Solano, Carlos, Ribera, Josep M., Pujal, Josep M., Hoyos, Montserrat, and Gallardo, David

Published
2007
Full Text
View/download PDF

49. Mobilization of Hematopoietic Stem Cells into Peripheral Blood for Autologous Transplantation Seems Less Efficacious in Poor Mobilizers with the Use of a Biosimilar of Filgrastim and Plerixafor: A Retrospective Comparative Analysis

Author

Universitat Rovira i Virgili, Parody, Rocio; Sanchez-Ortega, Isabel; Ferra, Christelle; Guardia, Ramon; Talarn, Carme; Encuentra, Maite; Fort, Eduard; Lopez, David; Morgades, Mireia; Alonso, Eva; Ortega, Sandra; Sarra, Josep; Gallardo, David; Ribera, Josep M.; Sureda, Anna, Universitat Rovira i Virgili, and Parody, Rocio; Sanchez-Ortega, Isabel; Ferra, Christelle; Guardia, Ramon; Talarn, Carme; Encuentra, Maite; Fort, Eduard; Lopez, David; Morgades, Mireia; Alonso, Eva; Ortega, Sandra; Sarra, Josep; Gallardo, David; Ribera, Josep M.; Sureda, Anna

Abstract

Introduction Biosimilars of granulocyte colony-stimulating factors (G-CSF) have shown similar efficacy to originator filgrastim (Neupogen (R) [NEU]; Amgen Inc.) as prophylaxis in neutropenia and in the mobilization of stem cells in patients receiving combination chemotherapy with G-CSF. Methods This was a retrospective study in which the characteristics of stem cell mobilization treated with a G-CSF alone were compared in 216 patients and 56 donors. The two G-CSF compared were NEU and the biosimilar filgrastim Zarzio (R) (Sandoz GmbH) (referred to hereafter as BIO). Primary objectives were mobilization rate (minimum of 10 x 10(3)/ml CD34+ on day 4 of treatment [day +4]) and use of the immunostimulant plerixafor (PLEX) in each group. Results The general characteristics of the patients receiving NEU (n = 138) and those receiving BIO (n = 78) did not differ significantly. PLEX was used in 24% of BIO patients and in 25.7% of NEU patients. The median CD34+ cell count on day +4 was significantly lower in BIO patients who needed PLEX than in those who did not (2.4 vs. 4.8 x 10(3)/ml; p = 0.002), as was the final CD34+ cell count (2.5 vs. 3.3 x 10(6)/kg; p 0.03). Mobilization failure rate was higher in the BIO group than in the NEU group (20 vs. 0%; p = 0.01). With respect to donors, more than one apheresis was needed in three BIO donors, one of them with PLEX. The use of BIO was the only risk factor for mobilization failure in patients who needed PLEX (hazard ratio 10.3; 95% confidence interval 1.3-77.8). Conclusion The study revealed that BIO had a lower efficacy for stem cell mobilization when the only treatment was G-CSF, especially in poor mobilizers needing PLEX.

Published
2020

Catalog

Books, media, physical & digital resources
See catalog results