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1. Temporal Trends in Takotsubo Syndrome: Results From the International Takotsubo Registry

Author

Schweiger, Victor, Cammann, Victoria L., Crisci, Giulia, Gilhofer, Thomas, Schlenker, Rabea, Niederseer, David, Chen, Shaojie, Ebrahimi, Ramin, Wenzl, Florian, Würdinger, Michael, Citro, Rodolfo, Vecchione, Carmine, Gili, Sebastiano, Neuhaus, Michael, Franke, Jennifer, Meder, Benjamin, Jaguszewski, Miłosz, Noutsias, Michel, Knorr, Maike, Jansen, Thomas, D’Ascenzo, Fabrizio, Dichtl, Wolfgang, von Lewinski, Dirk, Burgdorf, Christof, Kherad, Behrouz, Tschöpe, Carsten, Sarcon, Annahita, Shinbane, Jerold, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Koenig, Wolfgang, Pott, Alexander, Meyer, Philippe, Roffi, Marco, Banning, Adrian, Wolfrum, Mathias, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K.E. Juhani, Napp, L. Christian, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Chan, Christina, Bridgman, Paul, Beug, Daniel, Delmas, Clément, Lairez, Olivier, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, El-Battrawy, Ibrahim, Akin, Ibrahim, Poledniková, Karolina, Toušek, Petr, Winchester, David E., Massoomi, Michael, Galuszka, Jan, Ukena, Christian, Poglajen, Gregor, Carrilho-Ferreira, Pedro, Hauck, Christian, Paolini, Carla, Bilato, Claudio, Kobayashi, Yoshio, Kato, Ken, Ishibashi, Iwao, Himi, Toshiharu, Din, Jehangir, Al-Shammari, Ali, Prasad, Abhiram, Rihal, Charanjit S., Liu, Kan, Schulze, P. Christian, Bianco, Matteo, Jörg, Lucas, Rickli, Hans, Pestana, Gonçalo, Nguyen, Thanh H., Böhm, Michael, Maier, Lars S., Pinto, Fausto J., Widimský, Petr, Felix, Stephan B., Braun-Dullaeus, Ruediger C., Rottbauer, Wolfgang, Hasenfuß, Gerd, Pieske, Burkert M., Schunkert, Heribert, Budnik, Monika, Opolski, Grzegorz, Thiele, Holger, Bauersachs, Johann, Horowitz, John D., Di Mario, Carlo, Kong, William, Dalakoti, Mayank, Imori, Yoichi, Münzel, Thomas, Liberale, Luca, Montecucco, Fabrizio, Bax, Jeroen J., Crea, Filippo, Ruschitzka, Frank, Lüscher, Thomas F., Ghadri, Jelena R., Bossone, Eduardo, Templin, Christian, and Di Vece, Davide

Published
2024
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2. Ethnic comparison in takotsubo syndrome: novel insights from the International Takotsubo Registry

Author

Imori, Yoichi, Kato, Ken, Cammann, Victoria L., Szawan, Konrad A., Wischnewsky, Manfred, Dreiding, Sara, Würdinger, Michael, Schönberger, Maximilian, Petkova, Vanya, Niederseer, David, Levinson, Rena A., Di Vece, Davide, Gili, Sebastiano, Seifert, Burkhardt, Wakita, Masaki, Suzuki, Noriko, Citro, Rodolfo, Bossone, Eduardo, Heiner, Susanne, Knorr, Maike, Jansen, Thomas, Münzel, Thomas, D’Ascenzo, Fabrizio, Franke, Jennifer, Sorici-Barb, Ioana, Katus, Hugo A., Sarcon, Annahita, Shinbane, Jerold, Napp, L. Christian, Bauersachs, Johann, Jaguszewski, Milosz, Shiomura, Reiko, Nakamura, Shunichi, Takano, Hitoshi, Noutsias, Michel, Burgdorf, Christof, Ishibashi, Iwao, Himi, Toshiharu, Koenig, Wolfgang, Schunkert, Heribert, Thiele, Holger, Kherad, Behrouz, Tschöpe, Carsten, Pieske, Burkert M., Rajan, Lawrence, Michels, Guido, Pfister, Roman, Mizuno, Shingo, Cuneo, Alessandro, Jacobshagen, Claudius, Hasenfuß, Gerd, Karakas, Mahir, Mochizuki, Hiroki, Pott, Alexander, Rottbauer, Wolfgang, Said, Samir M., Braun-Dullaeus, Ruediger C., Banning, Adrian, Isogai, Toshiaki, Kimura, Akihisa, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Tomita, Yasuhiro, Budnik, Monika, Opolski, Grzegorz, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Crea, Filippo, Dichtl, Wolfgang, Murakami, Tsutomu, Ikari, Yuji, Empen, Klaus, Beug, Daniel, Felix, Stephan B., Delmas, Clément, Lairez, Olivier, Yamaguchi, Tetsuo, El-Battrawy, Ibrahim, Akin, Ibrahim, Borggrefe, Martin, Horowitz, John D., Kozel, Martin, Tousek, Petr, Widimský, Petr, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Neuhaus, Michael, Meyer, Philippe, Arroja, Jose David, Chan, Christina, Bridgman, Paul, Galuszka, Jan, Poglajen, Gregor, Carrilho-Ferreira, Pedro, Pinto, Fausto J., Hauck, Christian, Maier, Lars S., Liu, Kan, Di Mario, Carlo, Paolini, Carla, Bilato, Claudio, Bianco, Matteo, Jörg, Lucas, Rickli, Hans, Winchester, David E., Ukena, Christian, Böhm, Michael, Bax, Jeroen J., Prasad, Abhiram, Rihal, Charanjit S., Saito, Shigeru, Kobayashi, Yoshio, Lüscher, Thomas F., Ruschitzka, Frank, Shimizu, Wataru, Ghadri, Jelena R., and Templin, Christian

Published
2022
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3. Cardiac biomarkers for diagnosing Takotsubo syndrome

Author

Schweiger, Victor, primary, Di Vece, Davide, additional, Cammann, Victoria L, additional, Koleva, Iva, additional, Würdinger, Michael, additional, Gilhofer, Thomas, additional, Rajman, Katja, additional, Szawan, Konrad A, additional, Niederseer, David, additional, Citro, Rodolfo, additional, Vecchione, Carmine, additional, Bossone, Eduardo, additional, Gili, Sebastiano, additional, Neuhaus, Michael, additional, Franke, Jennifer, additional, Meder, Benjamin, additional, Jaguszewski, Miłosz, additional, Noutsias, Michel, additional, Knorr, Maike, additional, Jansen, Thomas, additional, D’Ascenzo, Fabrizio, additional, Bruno, Francesco, additional, De Filippo, Ovidio, additional, Stefanini, Giulio, additional, Campo, Gianluca, additional, Wanha, Wojciech, additional, Roubin, Sergio Raposeiras, additional, Dichtl, Wolfgang, additional, von Lewinski, Dirk, additional, Burgdorf, Christof, additional, Kherad, Behrouz, additional, Tschöpe, Carsten, additional, Sarcon, Annahita, additional, Shinbane, Jerold, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Koenig, Wolfgang, additional, Pott, Alexander, additional, Meyer, Philippe, additional, Roffi, Marco, additional, Banning, Adrian, additional, Wolfrum, Mathias, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A, additional, Vasankari, Tuija, additional, Airaksinen, K E Juhani, additional, Napp, L Christian, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, El-Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Poledniková, Karolina, additional, Toušek, Petr, additional, Winchester, David E, additional, Massoomi, Michael, additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Carrilho-Ferreira, Pedro, additional, Hauck, Christian, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Kobayashi, Yoshio, additional, Kato, Ken, additional, Ishibashi, Iwao, additional, Himi, Toshiharu, additional, Din, Jehangir, additional, Al-Shammari, Ali, additional, Prasad, Abhiram, additional, Rihal, Charanjit S, additional, Liu, Kan, additional, Schulze, P Christian, additional, Bianco, Matteo, additional, Jörg, Lucas, additional, Rickli, Hans, additional, Pestana, Gonçalo, additional, Nguyen, Thanh H, additional, Böhm, Michael, additional, Maier, Lars S, additional, Pinto, Fausto J, additional, Widimský, Petr, additional, Felix, Stephan B, additional, Braun-Dullaeus, Ruediger C, additional, Rottbauer, Wolfgang, additional, Hasenfuß, Gerd, additional, Pieske, Burkert M, additional, Schunkert, Heribert, additional, Budnik, Monika, additional, Opolski, Grzegorz, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Horowitz, John D, additional, Di Mario, Carlo, additional, Kong, William, additional, Dalakoti, Mayank, additional, Imori, Yoichi, additional, Münzel, Thomas, additional, Bax, Jeroen J, additional, Lüscher, Thomas F, additional, Crea, Filippo, additional, Ruschitzka, Frank, additional, Ghadri, Jelena R, additional, and Templin, Christian, additional

Published
2024
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4. Synkopy v průběhu testu na nakloněné rovině ve vztahu k farmakoterapii potenciálně ovlivňující ortostatickou intoleranci vyšetřovaných osob.

Author

Galuszka, Jan, Kaiserová, Michaela, Zapletalová, Jana, and Táborský, Miloš

Abstract

Copyright of Medicina Pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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5. Machine learning‐based prediction of in‐hospital death for patients with takotsubo syndrome: The InterTAK‐ML model

Author

De Filippo, Ovidio, primary, Cammann, Victoria L., additional, Pancotti, Corrado, additional, Di Vece, Davide, additional, Silverio, Angelo, additional, Schweiger, Victor, additional, Niederseer, David, additional, Szawan, Konrad A., additional, Würdinger, Michael, additional, Koleva, Iva, additional, Dusi, Veronica, additional, Bellino, Michele, additional, Vecchione, Carmine, additional, Parodi, Guido, additional, Bossone, Eduardo, additional, Gili, Sebastiano, additional, Neuhaus, Michael, additional, Franke, Jennifer, additional, Meder, Benjamin, additional, Jaguszewski, Miłosz, additional, Noutsias, Michel, additional, Knorr, Maike, additional, Jansen, Thomas, additional, Dichtl, Wolfgang, additional, von Lewinski, Dirk, additional, Burgdorf, Christof, additional, Kherad, Behrouz, additional, Tschöpe, Carsten, additional, Sarcon, Annahita, additional, Shinbane, Jerold, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Koenig, Wolfgang, additional, Pott, Alexander, additional, Meyer, Philippe, additional, Roffi, Marco, additional, Banning, Adrian, additional, Wolfrum, Mathias, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A., additional, Vasankari, Tuija, additional, Airaksinen, K.E. Juhani, additional, Napp, L. Christian, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, El‐Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Poledniková, Karolina, additional, Toušek, Petr, additional, Winchester, David E., additional, Massoomi, Michael, additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Carrilho‐Ferreira, Pedro, additional, Hauck, Christian, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Kobayashi, Yoshio, additional, Kato, Ken, additional, Ishibashi, Iwao, additional, Himi, Toshiharu, additional, Din, Jehangir, additional, Al‐Shammari, Ali, additional, Prasad, Abhiram, additional, Rihal, Charanjit S., additional, Liu, Kan, additional, Schulze, P. Christian, additional, Bianco, Matteo, additional, Jörg, Lucas, additional, Rickli, Hans, additional, Pestana, Gonçalo, additional, Nguyen, Thanh H., additional, Böhm, Michael, additional, Maier, Lars S., additional, Pinto, Fausto J., additional, Widimský, Petr, additional, Felix, Stephan B., additional, Braun‐Dullaeus, Ruediger C., additional, Rottbauer, Wolfgang, additional, Hasenfuß, Gerd, additional, Pieske, Burkert M., additional, Schunkert, Heribert, additional, Budnik, Monika, additional, Opolski, Grzegorz, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Horowitz, John D., additional, Di Mario, Carlo, additional, Bruno, Francesco, additional, Kong, William, additional, Dalakoti, Mayank, additional, Imori, Yoichi, additional, Münzel, Thomas, additional, Crea, Filippo, additional, Lüscher, Thomas F., additional, Bax, Jeroen J., additional, Ruschitzka, Frank, additional, De Ferrari, Gaetano Maria, additional, Fariselli, Piero, additional, Ghadri, Jelena R., additional, Citro, Rodolfo, additional, D'Ascenzo, Fabrizio, additional, and Templin, Christian, additional

Published
2023
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7. Intraventricular Thrombus Formation and Embolism in Takotsubo Syndrome: Insights From the International Takotsubo Registry

Author

Ding, Katharina J., Cammann, Victoria L., Szawan, Konrad A., Stähli, Barbara E., Wischnewsky, Manfred, Di Vece, Davide, Citro, Rodolfo, Jaguszewski, Milosz, Seifert, Burkhardt, Sarcon, Annahita, Knorr, Maike, Heiner, Susanne, Gili, Sebastiano, D’Ascenzo, Fabrizio, Neuhaus, Michael, Napp, L. Christian, Franke, Jennifer, Noutsias, Michel, Burgdorf, Christof, Koenig, Wolfgang, Kherad, Behrouz, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Pott, Alexander, Meyer, Philippe, Arroja, Jose D., Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K.E. Juhani, Paolini, Carla, Bilato, Claudio, Carrilho-Ferreira, Pedro, Opolski, Grzegorz, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Dichtl, Wolfgang, Chan, Christina, Bridgman, Paul, Delmas, Clément, Lairez, Olivier, El-Battrawy, Ibrahim, Akin, Ibrahim, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Kozel, Martin, Tousek, Petr, Widimský, Petr, Winchester, David E., Galuszka, Jan, Ukena, Christian, Horowitz, John D., Di Mario, Carlo, Prasad, Abhiram, Rihal, Charanjit S., Pinto, Fausto J., Crea, Filippo, Borggrefe, Martin, Braun-Dullaeus, Ruediger C., Rottbauer, Wolfgang, Bauersachs, Johann, Katus, Hugo A., Hasenfuß, Gerd, Tschöpe, Carsten, Pieske, Burkert M., Thiele, Holger, Schunkert, Heribert, Böhm, Michael, Felix, Stephan B., Münzel, Thomas, Bax, Jeroen J., Lüscher, Thomas F., Ruschitzka, Frank, Ghadri, Jelena R., Bossone, Eduardo, and Templin, Christian

Published
2020
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10. Technical and Economical Evaluation of WGSR

Author

Ciambelli, Paolo, Palma, Vincenzo, Palo, Emma, Galuszka, Jan, Giddings, Terry, Iaquaniello, Gaetano, eStudio Calamar S.L., De De Falco, Marcello, editor, Marrelli, Luigi, editor, and Iaquaniello, Gaetano, editor

Published
2011
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15. Clinical effectiveness of primary prevention implantable cardioverter-defibrillators: results of the EU-CERT-ICD controlled multicentre cohort study

Author

Zabel, Markus, Willems, Rik, Lubinski, Andrzej, Bauer, Axel, Brugada, Josep, Conen, David, Flevari, Panagiota, Hasenfuß, Gerd, Svetlosak, Martin, Huikuri, Heikki V, Malik, Marek, Pavlović, Nikola, Schmidt, Georg, Sritharan, Rajevaa, Schlögl, Simon, Szavits-Nossan, Janko, Traykov, Vassil, Tuinenburg, Anton E, Willich, Stefan N, Harden, Markus, Friede, Tim, Svendsen, Jesper Hastrup, Sticherling, Christian, Merkely, Béla, Perge, Peter, Sallo, Zoltan, Szeplaki, Gabor, Szegedi, Nandor, Nagy, Klaudia Vivien, Lüthje, Lars, Sritharan, R, Haarmann, Helge, Bergau, Leonard, Seegers, Joachim, Munoz- Exposito, Pascal, Tichelbäcker, Tobias, Kirova, Aleksandra, Hnatkova, Katerina, Vos, Marc A, Reinhold, Thomas, Vandenberk, Bert, Klinika, Magdalena, Rotkvić, L, Flevari, Panayota, Katsimardos, Andreas, Katsaras, Dimitrios, Hatala, Robert, Kuczejko, Tomasz, Hansen, Jim, Manola, Šime, Vinter, Ozren, Benko, Ivica, Tuinenburg, Anton, Sprenkeler, David, Smoczynska, A, Vos, M A, Meyer-Zürn, Christine, Eick, Christian, Arbelo, Elena, Kaliska, Gabriela, Martinek, Jozef, Dommasch, Michael, Steger, Alexander, Kääb, Stefan, Sinner, Moritz F, Rizas, Konstantinos D, Hamm, Wolfgang, Traykov, V, Cygankiewicz, Iwona, Ptaszyński, Pawel, Kaczmarek, K, Poddebska, I, Iovev, Svetoslav, Novotný, Tomáš, Kozak, Milan, Huikuri, Heikki, Kenttä, Tuomas, Pelli, Ari, Kasprzak, Jaroslaw D, Qavoq, Dariusz, Brusich, Sandro, Avdovic, Ervin, Klasan, Marina, Galuszka, Jan, Taborsky, Milos, Velchev, Vasil, Dissmann, Rüdiger, Shalganov, T, Guzik, P, Krauze, T, Bimmel, Dieter, Lieberz, Christiane, Ludwigsburg, Klinikum, Stefanow, Stefan, Rüb, Norman, Wolpert, Christian, Meier, Lars S, Behrens, Steffen, Jurisic, Zrinka, Braunschweig, Frieder, Blaschke, Florian, Pieske, Burkert, Bakotic, Zoran, Anic, Ante, Weiden, Klinikum, Schwinger, Robert H G, Platonov, Pyotr, Grönefeld, Gerian, Klingenheben, Thomas, and EU-CERT-ICD Study Investigators

Subjects
medicine.medical_specialty, medicine.medical_treatment, Implantable cardioverter-defibrillator, Risk factors, Mortality, Sudden cardiac death, 030204 cardiovascular system & hematology, Ventricular Function, Left, Cohort Studies, EU-CERT-ICD Study Investigators, 03 medical and health sciences, 0302 clinical medicine, Clinical Research, Internal medicine, medicine, Clinical endpoint, Humans, AcademicSubjects/MED00200, Prospective Studies, 030212 general & internal medicine, BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Internal Medicine, 1102 Cardiorespiratory Medicine and Haematology, Aged, BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Interna medicina, Heart Failure, Ejection fraction, Ischemic cardiomyopathy, business.industry, Hazard ratio, Stroke Volume, 1103 Clinical Sciences, Dilated cardiomyopathy, medicine.disease, Confidence interval, Defibrillators, Implantable, 3. Good health, Europe, Primary Prevention, Death, Sudden, Cardiac, Treatment Outcome, Cardiovascular System & Hematology, Implantable cardioverter-defibrillator, Risk factors, Mortality, Sudden cardiac death, Cardiology and Cardiovascular Medicine, business, Cohort study
Abstract

Aims The EUropean Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter-Defibrillators (EU-CERT-ICD), a prospective investigator-initiated, controlled cohort study, was conducted in 44 centres and 15 European countries. It aimed to assess current clinical effectiveness of primary prevention ICD therapy. Methods and results We recruited 2327 patients with ischaemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM) and guideline indications for prophylactic ICD implantation. Primary endpoint was all-cause mortality. Clinical characteristics, medications, resting, and 12-lead Holter electrocardiograms (ECGs) were documented at enrolment baseline. Baseline and follow-up (FU) data from 2247 patients were analysable, 1516 patients before first ICD implantation (ICD group) and 731 patients without ICD serving as controls. Multivariable models and propensity scoring for adjustment were used to compare the two groups for mortality. During mean FU of 2.4 ± 1.1 years, 342 deaths occurred (6.3%/years annualized mortality, 5.6%/years in the ICD group vs. 9.2%/years in controls), favouring ICD treatment [unadjusted hazard ratio (HR) 0.682, 95% confidence interval (CI) 0.537–0.865, P = 0.0016]. Multivariable mortality predictors included age, left ventricular ejection fraction (LVEF), New York Heart Association class Conclusion In contemporary ICM/DCM patients (LVEF ≤35%, narrow QRS), primary prophylactic ICD treatment was associated with a 27% lower mortality after adjustment. There appear to be patients with less survival advantage, such as older patients or diabetics.

Published
2020

16. Impact of Atrial Fibrillation on Outcome in Takotsubo Syndrome: Data From the International Takotsubo Registry

Author

El‐Battrawy, Ibrahim, primary, Cammann, Victoria L., additional, Kato, Ken, additional, Szawan, Konrad A., additional, Di Vece, Davide, additional, Rossi, Aurelio, additional, Wischnewsky, Manfred, additional, Hermes‐Laufer, Julia, additional, Gili, Sebastiano, additional, Citro, Rodolfo, additional, Bossone, Eduardo, additional, Neuhaus, Michael, additional, Franke, Jennifer, additional, Meder, Benjamin, additional, Jaguszewski, Milosz, additional, Noutsias, Michel, additional, Knorr, Maike, additional, Heiner, Susanne, additional, D’Ascenzo, Fabrizio, additional, Dichtl, Wolfgang, additional, Burgdorf, Christof, additional, Kherad, Behrouz, additional, Tschöpe, Carsten, additional, Sarcon, Annahita, additional, Shinbane, Jerold, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Koenig, Wolfgang, additional, Pott, Alexander, additional, Meyer, Philippe, additional, David Arroja, Jose, additional, Banning, Adrian, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A., additional, Vasankari, Tuija, additional, Airaksinen, K. E. Juhani, additional, Napp, L. Christian, additional, Budnik, Monika, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, Kozel, Martin, additional, Tousek, Petr, additional, Winchester, David E., additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Carrilho‐Ferreira, Pedro, additional, Hauck, Christian, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Kobayashi, Yoshio, additional, Prasad, Abhiram, additional, Rihal, Charanjit S., additional, Liu, Kan, additional, Schulze, P. Christian, additional, Bianco, Matteo, additional, Jörg, Lucas, additional, Rickli, Hans, additional, Pestana, Gonçalo, additional, Nguyen, Thanh H., additional, Böhm, Michael, additional, Maier, Lars S., additional, Pinto, Fausto J., additional, Widimský, Petr, additional, Felix, Stephan B., additional, Opolski, Grzegorz, additional, Braun‐Dullaeus, Ruediger C., additional, Rottbauer, Wolfgang, additional, Hasenfuß, Gerd, additional, Pieske, Burkert M., additional, Schunkert, Heribert, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Katus, Hugo A., additional, Horowitz, John D., additional, Di Mario, Carlo, additional, Münzel, Thomas, additional, Crea, Filippo, additional, Bax, Jeroen J., additional, Lüscher, Thomas F., additional, Ruschitzka, Frank, additional, Duru, Firat, additional, Borggrefe, Martin, additional, Ghadri, Jelena R., additional, Akin, Ibrahim, additional, and Templin, Christian, additional

Published
2021
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17. Clinical correlates and prognostic impact of neurologic disorders in Takotsubo syndrome

Author

Cammann, Victoria L, Scheitz, Jan F., Ghadri, Jelena R, Budnik, Monika, Opolski, Grzegorz, Borggrefe, Martin, Thiele, Holger, Bauersachs, Johann, Katus, Hugo A, Horowitz, John D, Di Mario, Carlo, Münzel, Thomas, Crea, Filippo, Consortium, InterTAK, Bax, Jeroen J, Scherff, Frank, Niederseer, David, Lüscher, Thomas F, Citro, Rodolfo, Vecchione, Carmine, Bossone, Eduardo, Gili, Sebastiano, Neuhaus, Michael, Franke, Jennifer, Meder, Benjamin, Jaguszewski, Miłosz, von Rennenberg, Regina, Noutsias, Michel, Knorr, Maike, Jansen, Thomas, D'Ascenzo, Fabrizio, Dichtl, Wolfgang, Burgdorf, Christof, Kherad, Behrouz, Tschöpe, Carsten, Sarcon, Annahita, Shinbane, Jerold, Jäncke, Lutz, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Koenig, Wolfgang, Pott, Alexander, Meyer, Philippe, Roffi, Marco, Nolte, Christian, Banning, Adrian, Wolfrum, Mathias, Cuculi, Florim, Kobza, Richard, Fischer, Thomas, Vasankari, Tuija, Airaksinen, K E Juhani, Napp, L Christian, Dworakowski, Rafal, MacCarthy, Philip, Szawan, Konrad A, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Chan, Christina, Bridgman, Paul, Beug, Daniel, Delmas, Clément, Lairez, Olivier, Gilyarova, Ekaterina, Shilova, Alexandra, Stengl, Helena, Gilyarov, Mikhail, El-Battrawy, Ibrahim, Akin, Ibrahim, Poledniková, Karolina, Toušek, Petr, Winchester, David E, Galuszka, Jan, Ukena, Christian, Poglajen, Gregor, Carrilho-Ferreira, Pedro, Würdinger, Michael, Hauck, Christian, Paolini, Carla, Bilato, Claudio, Kobayashi, Yoshio, Kato, Ken, Shoji, Toshihiro, Ishibashi, Iwao, Takahara, Masayuki, Himi, Toshiharu, Din, Jehangir, Endres, Matthias, Al-Shammari, Ali, Prasad, Abhiram, Rihal, Charanjit S, Liu, Kan, Schulze, Peter, Bianco, Matteo, Jörg, Lucas, Rickli, Hans, Pestana, Gonçalo, Nguyen, Thanh H, Templin, Christian, Böhm, Michael, Maier, Lars S, Pinto, Fausto J, Widimský, Petr, Felix, Stephan B, Braun-Dullaeus, Ruediger C, Rottbauer, Wolfgang, Hasenfuß, Gerd, Pieske, Burkert M, Schunkert, Heribert, University of Zurich, and Repositório da Universidade de Lisboa

Subjects
Adult, Male, Science, Cardiology, heart disease risk factors, complications [Seizures], Article, Seizures, Takotsubo Cardiomyopathy, diagnosis [Takotsubo Cardiomyopathy], Humans, Hospital Mortality, Registries, humans, Ischemic Stroke, Aged, Aged, 80 and over, hospital mortality, mortality [Takotsubo Cardiomyopathy], Multidisciplinary, complications [Intracranial Hemorrhages], 10093 Institute of Psychology, etiology [Takotsubo Cardiomyopathy], Middle Aged, Prognosis, complications [Ischemic Stroke], Outcomes research, Heart Disease Risk Factors, 10209 Clinic for Cardiology, Medicine, Female, 150 Psychology, Intracranial Hemorrhages, ddc:600
Abstract

© The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/., Cardiac alterations are frequently observed after acute neurological disorders. Takotsubo syndrome (TTS) represents an acute heart failure syndrome and is increasingly recognized as part of the spectrum of cardiac complications observed after neurological disorders. A systematic investigation of TTS patients with neurological disorders has not been conducted yet. The aim of the study was to expand insights regarding neurological disease entities triggering TTS and to investigate the clinical profile and outcomes of TTS patients after primary neurological disorders. The International Takotsubo Registry is an observational multicenter collaborative effort of 45 centers in 14 countries (ClinicalTrials.gov, identifier NCT01947621). All patients in the registry fulfilled International Takotsubo Diagnostic Criteria. For the present study, patients were included if complete information on acute neurological disorders were available. 2402 patients in whom complete information on acute neurological status were available were analyzed. In 161 patients (6.7%) an acute neurological disorder was identified as the preceding triggering factor. The most common neurological disorders were seizures, intracranial hemorrhage, and ischemic stroke. Time from neurological symptoms to TTS diagnosis was ≤ 2 days in 87.3% of cases. TTS patients with neurological disorders were younger, had a lower female predominance, fewer cardiac symptoms, lower left ventricular ejection fraction, and higher levels of cardiac biomarkers. TTS patients with neurological disorders had a 3.2-fold increased odds of in-hospital mortality compared to TTS patients without neurological disorders. In this large-scale study, 1 out of 15 TTS patients had an acute neurological condition as the underlying triggering factor. Our data emphasize that a wide spectrum of neurological diseases ranging from benign to life-threatening encompass TTS. The high rates of adverse events highlight the need for clinical awareness., The International Takotsubo Registry was supported by the Biss Davies Charitable Trust. Dr. Scheitz has been supported by the Corona Foundation. Dr. Templin has been supported by the H.H. Sheikh Khalifa bin Hamad Al-Thani Research Programme and the Swiss Heart Foundation.

Published
2021

18. Q waves are the strongest electrocardiographic variable associated with primary prophylactic implantable cardioverter-defibrillator benefit: a prospective multicentre study

Author

Pelli, Ari, Junttila, M Juhani, Kenttä, Tuomas V, Schlögl, Simon, Zabel, Markus, Malik, Marek, Reichlin, Tobias, Willems, Rik, Vos, Marc A, Harden, Markus, Friede, Tim, Sticherling, Christian, Huikuri, Heikki V, Arbelo, Elena, Bauer, Axel, Braunschweig, Frieder, Brugada, Josep, Conen, David, Cygankiewicz, Iwona, Dommasch, Michael, Eick, Christian, Flevari, Panagiota, Galuszka, Jan, Hansen, Jim, Hatala, Robert, Hnatkova, Katerina, Junttila, Juhani M, Kääb, Stefan, Kaliska, Gabriela, Kasprzak, Jaroslaw D, Katsimardos, Andreas, Kozak, Milan, Kuczejko, Tomasz, Lubinski, Andrzej, Martinek, Jozef, Merkely, Béla, Novotný, Tomáš, Perge, Peter, Pieske, Burkert, Platonov, Pyotr, Ptaczyński, Pawel, Qavoq, Dariusz, Rotkvić, L, Sallo, Zoltan, Schmidt, Georg, Sinner, Moritz, Sritharan, Rajeeva, Stefanow, Stefan, Svendsen, Jesper Hastrup, Svetlosak, Martin, Szavits-Nossan, Janko, Taborsky, Milos, Tuinenburg, Anton, Vandenberk, Bert, Willich, Stefan N, Wolpert, Christian, Anic, Ante, Bakotic, Zoran, Behrens, Steffen, Bimmel, Dieter, Brusich, Sandro, Dissmann, Rüdiger, Grönefeld, Gerian, Guzik, Przemyzlav, Iovev, Svetoslav, Jurisic, Zrinka, Klingenheben, Thomas, Pavlović, Nikola, Seegers, Joachim, Schwinger, Robert H G, Shalganov, Tchavdar, Traykov, Vassil, Velchev, Vasil, and the EU-CERT-ICD Study Investigators

Subjects
QT interval, medicine.medical_specialty, medicine.medical_treatment, Population, 610 Medicine & health, Heart failure, Benefit, 030204 cardiovascular system & hematology, Implantable cardioverter-defibrillator, 03 medical and health sciences, Electrocardiography, 0302 clinical medicine, Risk Factors, Physiology (medical), Internal medicine, Medicine, Humans, 030212 general & internal medicine, Prospective Studies, Mortality, education, Pathological, education.field_of_study, Primary prevention, business.industry, Incidence (epidemiology), Hazard ratio, Arrhythmias, Cardiac, Appropriate shock, Electrocardiogram, Q wave, medicine.disease, Confidence interval, Defibrillators, Implantable, Primary Prevention, Death, Sudden, Cardiac, Cardiology, Cardiology and Cardiovascular Medicine, business
Abstract

Aim The association of standard 12-lead electrocardiogram (ECG) markers with benefits of the primary prophylactic implantable cardioverter-defibrillator (ICD) has not been determined in the contemporary era. We analysed traditional and novel ECG variables in a large prospective, controlled primary prophylactic ICD population to assess the predictive value of ECG in terms of ICD benefit. Methods and results Electrocardiograms from 1477 ICD patients and 700 control patients (EU-CERT-ICD; non-randomized, controlled, prospective multicentre study; ClinicalTrials.gov Identifier: NCT02064192), who met ICD implantation criteria but did not receive the device, were analysed. The primary outcome was all-cause mortality. In ICD patients, the co-primary outcome of first appropriate shock was used. Mean follow-up time was 2.4 ± 1.1 years to death and 2.3 ± 1.2 years to the first appropriate shock. Pathological Q waves were associated with decreased mortality in ICD patients [hazard ratio (HR) 0.54, 95% confidence interval (CI) 0.35–0.84; P Conclusion Pathological Q waves were a strong ECG predictor of ICD benefit in primary prophylactic ICD patients. Excess mortality among Q wave patients seems to be due to arrhythmic death which can be prevented by ICD.

Published
2021

19. Impact of Atrial Fibrillation on Outcome in Takotsubo Syndrome: Data From the International Takotsubo Registry

Author

El-Battrawy, Ibrahim, Cammann, Victoria L., Kato, Ken, Szawan, Konrad A., Di Vece, Davide, Rossi, Aurelio, Wischnewsky, Manfred, Hermes-Laufer, Julia, Gili, Sebastiano, Citro, Rodolfo, Bossone, Eduardo, Neuhaus, Michael, Franke, Jennifer, Meder, Benjamin, Jaguszewski, Milosz, Noutsias, Michel, Knorr, Maike, Heiner, Susanne, D'Ascenzo, Fabrizio, Dichtl, Wolfgang, Burgdorf, Christof, Kherad, Behrouz, Tschoepe, Carsten, Sarcon, Annahita, Shinbane, Jerold, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Koenig, Wolfgang, Pott, Alexander, Meyer, Philippe, Arroja, Jose David, Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Napp, L. Christian, Budnik, Monika, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Chan, Christina, Bridgman, Paul, Beug, Daniel, Delmas, Clement, Lairez, Olivier, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Kozel, Martin, Tousek, Petr, Winchester, David E., Galuszka, Jan, Ukena, Christian, Poglajen, Gregor, Carrilho-Ferreira, Pedro, Hauck, Christian, Paolini, Carla, Bilato, Claudio, Kobayashi, Yoshio, Prasad, Abhiram, Rihal, Charanjit S., Liu, Kan, Schulze, P. Christian, Bianco, Matteo, Joerg, Lucas, Rickli, Hans, Pestana, Goncalo, Nguyen, Thanh H., Boehm, Michael, Maier, Lars S., Pinto, Fausto J., Widimsky, Petr, Felix, Stephan B., Opolski, Grzegorz, Braun-Dullaeus, Ruediger C., Rottbauer, Wolfgang, Hasenfuss, Gerd, Pieske, Burkert M., Schunkert, Heribert, Thiele, Holger, Bauersachs, Johann, Katus, Hugo A., Horowitz, John D., Di Mario, Carlo, Muenzel, Thomas, Crea, Filippo, Bax, Jeroen J., Luescher, Thomas F., Ruschitzka, Frank, Duru, Firat, Borggrefe, Martin, Ghadri, Jelena R., Akin, Ibrahim, Templin, Christian, El-Battrawy, Ibrahim, Cammann, Victoria L., Kato, Ken, Szawan, Konrad A., Di Vece, Davide, Rossi, Aurelio, Wischnewsky, Manfred, Hermes-Laufer, Julia, Gili, Sebastiano, Citro, Rodolfo, Bossone, Eduardo, Neuhaus, Michael, Franke, Jennifer, Meder, Benjamin, Jaguszewski, Milosz, Noutsias, Michel, Knorr, Maike, Heiner, Susanne, D'Ascenzo, Fabrizio, Dichtl, Wolfgang, Burgdorf, Christof, Kherad, Behrouz, Tschoepe, Carsten, Sarcon, Annahita, Shinbane, Jerold, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Koenig, Wolfgang, Pott, Alexander, Meyer, Philippe, Arroja, Jose David, Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Napp, L. Christian, Budnik, Monika, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Chan, Christina, Bridgman, Paul, Beug, Daniel, Delmas, Clement, Lairez, Olivier, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Kozel, Martin, Tousek, Petr, Winchester, David E., Galuszka, Jan, Ukena, Christian, Poglajen, Gregor, Carrilho-Ferreira, Pedro, Hauck, Christian, Paolini, Carla, Bilato, Claudio, Kobayashi, Yoshio, Prasad, Abhiram, Rihal, Charanjit S., Liu, Kan, Schulze, P. Christian, Bianco, Matteo, Joerg, Lucas, Rickli, Hans, Pestana, Goncalo, Nguyen, Thanh H., Boehm, Michael, Maier, Lars S., Pinto, Fausto J., Widimsky, Petr, Felix, Stephan B., Opolski, Grzegorz, Braun-Dullaeus, Ruediger C., Rottbauer, Wolfgang, Hasenfuss, Gerd, Pieske, Burkert M., Schunkert, Heribert, Thiele, Holger, Bauersachs, Johann, Katus, Hugo A., Horowitz, John D., Di Mario, Carlo, Muenzel, Thomas, Crea, Filippo, Bax, Jeroen J., Luescher, Thomas F., Ruschitzka, Frank, Duru, Firat, Borggrefe, Martin, Ghadri, Jelena R., Akin, Ibrahim, and Templin, Christian

Abstract

Background Atrial fibrillation (AF) is a major risk factor for mortality. The prevalence, clinical correlates, and prognostic impact of AF in Takotsubo syndrome (TTS) have not yet been investigated in a large patient cohort. This study aimed to investigate the prevalence, clinical correlates, and prognostic impact of AF in patients with TTS. Methods and Results Patients with TTS were enrolled from the International Takotsubo Registry, which is a multinational network with 26 participating centers in Europe and the United States. Patients were dichotomized according to the presence or absence of AF at the time of admission. Of 1584 patients with TTS, 112 (7.1%) had AF. The mean age was higher (P<0.001), and there were fewer women (P=0.046) in the AF than in the non-AF group. Left ventricular ejection fraction was significantly lower (P=0.001), and cardiogenic shock was more often observed (P<0.001) in the AF group. Both in-hospital (P<0.001) and long-term mortality (P<0.001) were higher in the AF group. Multivariable Cox regression analysis revealed that AF was independently associated with higher long-term mortality (hazard ratio, 2.31; 95% CI, 1.50-3.55; P<0.001). Among patients with AF on admission, 42% had no known history of AF before the acute TTS event, and such patients had comparable in-hospital and long-term outcomes compared with those with a history of AF. Conclusions In patients presenting with TTS, AF on admission is significantly associated with increased in-hospital and long-term mortality rates. Whether antiarrhythmics and/or cardioversion are beneficial in TTS with AF should thus be tested in a future trial. Registration URL: ; Unique identifier: NCT01947621.

Published
2021

21. Ethnic comparison in takotsubo syndrome: novel insights from the International Takotsubo Registry

Author

Imori, Yoichi, primary, Kato, Ken, additional, Cammann, Victoria L., additional, Szawan, Konrad A., additional, Wischnewsky, Manfred, additional, Dreiding, Sara, additional, Würdinger, Michael, additional, Schönberger, Maximilian, additional, Petkova, Vanya, additional, Niederseer, David, additional, Levinson, Rena A., additional, Di Vece, Davide, additional, Gili, Sebastiano, additional, Seifert, Burkhardt, additional, Wakita, Masaki, additional, Suzuki, Noriko, additional, Citro, Rodolfo, additional, Bossone, Eduardo, additional, Heiner, Susanne, additional, Knorr, Maike, additional, Jansen, Thomas, additional, Münzel, Thomas, additional, D’Ascenzo, Fabrizio, additional, Franke, Jennifer, additional, Sorici-Barb, Ioana, additional, Katus, Hugo A., additional, Sarcon, Annahita, additional, Shinbane, Jerold, additional, Napp, L. Christian, additional, Bauersachs, Johann, additional, Jaguszewski, Milosz, additional, Shiomura, Reiko, additional, Nakamura, Shunichi, additional, Takano, Hitoshi, additional, Noutsias, Michel, additional, Burgdorf, Christof, additional, Ishibashi, Iwao, additional, Himi, Toshiharu, additional, Koenig, Wolfgang, additional, Schunkert, Heribert, additional, Thiele, Holger, additional, Kherad, Behrouz, additional, Tschöpe, Carsten, additional, Pieske, Burkert M., additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Mizuno, Shingo, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Hasenfuß, Gerd, additional, Karakas, Mahir, additional, Mochizuki, Hiroki, additional, Pott, Alexander, additional, Rottbauer, Wolfgang, additional, Said, Samir M., additional, Braun-Dullaeus, Ruediger C., additional, Banning, Adrian, additional, Isogai, Toshiaki, additional, Kimura, Akihisa, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A., additional, Vasankari, Tuija, additional, Airaksinen, K. E. Juhani, additional, Tomita, Yasuhiro, additional, Budnik, Monika, additional, Opolski, Grzegorz, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Crea, Filippo, additional, Dichtl, Wolfgang, additional, Murakami, Tsutomu, additional, Ikari, Yuji, additional, Empen, Klaus, additional, Beug, Daniel, additional, Felix, Stephan B., additional, Delmas, Clément, additional, Lairez, Olivier, additional, Yamaguchi, Tetsuo, additional, El-Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Borggrefe, Martin, additional, Horowitz, John D., additional, Kozel, Martin, additional, Tousek, Petr, additional, Widimský, Petr, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, Neuhaus, Michael, additional, Meyer, Philippe, additional, Arroja, Jose David, additional, Chan, Christina, additional, Bridgman, Paul, additional, Galuszka, Jan, additional, Poglajen, Gregor, additional, Carrilho-Ferreira, Pedro, additional, Pinto, Fausto J., additional, Hauck, Christian, additional, Maier, Lars S., additional, Liu, Kan, additional, Di Mario, Carlo, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Bianco, Matteo, additional, Jörg, Lucas, additional, Rickli, Hans, additional, Winchester, David E., additional, Ukena, Christian, additional, Böhm, Michael, additional, Bax, Jeroen J., additional, Prasad, Abhiram, additional, Rihal, Charanjit S., additional, Saito, Shigeru, additional, Kobayashi, Yoshio, additional, Lüscher, Thomas F., additional, Ruschitzka, Frank, additional, Shimizu, Wataru, additional, Ghadri, Jelena R., additional, and Templin, Christian, additional

Published
2021
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22. Prognostic impact of acute pulmonary triggers in patients with takotsubo syndrome: new insights from the International Takotsubo Registry

Author

Kato, Ken, primary, Cammann, Victoria L., additional, Napp, L. Christian, additional, Szawan, Konrad A., additional, Micek, Jozef, additional, Dreiding, Sara, additional, Levinson, Rena A., additional, Petkova, Vanya, additional, Würdinger, Michael, additional, Patrascu, Alexandru, additional, Sumalinog, Rafael, additional, Gili, Sebastiano, additional, Clarenbach, Christian F., additional, Kohler, Malcolm, additional, Wischnewsky, Manfred, additional, Citro, Rodolfo, additional, Vecchione, Carmine, additional, Bossone, Eduardo, additional, Neuhaus, Michael, additional, Franke, Jennifer, additional, Meder, Benjamin, additional, Jaguszewski, Milosz, additional, Noutsias, Michel, additional, Knorr, Maike, additional, Heiner, Susanne, additional, D'Ascenzo, Fabrizio, additional, Dichtl, Wolfgang, additional, Burgdorf, Christof, additional, Kherad, Behrouz, additional, Tschöpe, Carsten, additional, Sarcon, Annahita, additional, Shinbane, Jerold, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Koenig, Wolfgang, additional, Pott, Alexander, additional, Meyer, Philippe, additional, Roffi, Marco, additional, Banning, Adrian, additional, Wolfrum, Mathias, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A., additional, Vasankari, Tuija, additional, Airaksinen, K.E. Juhani, additional, Budnik, Monika, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, El‐Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Kozel, Martin, additional, Tousek, Petr, additional, Winchester, David E., additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Carrilho‐Ferreira, Pedro, additional, Hauck, Christian, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Sano, Masanori, additional, Ishibashi, Iwao, additional, Takahara, Masayuki, additional, Himi, Toshiharu, additional, Kobayashi, Yoshio, additional, Prasad, Abhiram, additional, Rihal, Charanjit S., additional, Liu, Kan, additional, Schulze, P. Christian, additional, Bianco, Matteo, additional, Jörg, Lucas, additional, Rickli, Hans, additional, Pestana, Gonçalo, additional, Nguyen, Thanh H., additional, Böhm, Michael, additional, Maier, Lars S., additional, Pinto, Fausto J., additional, Widimský, Petr, additional, Felix, Stephan B., additional, Opolski, Grzegorz, additional, Braun‐Dullaeus, Ruediger C., additional, Rottbauer, Wolfgang, additional, Hasenfuß, Gerd, additional, Pieske, Burkert M., additional, Schunkert, Heribert, additional, Borggrefe, Martin, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Katus, Hugo A., additional, Horowitz, John D., additional, Di Mario, Carlo, additional, Münzel, Thomas, additional, Crea, Filippo, additional, Bax, Jeroen J., additional, Lüscher, Thomas F., additional, Ruschitzka, Frank, additional, Ghadri, Jelena R., additional, and Templin, Christian, additional

Published
2021
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23. Appropriate Shocks and Mortality in Patients With Versus Without Diabetes With Prophylactic Implantable Cardioverter Defibrillators

Author

Junttila, M. Juhani, Pelli, Ari, Kenttä, Tuomas V., Friede, Tim, Willems, Rik, Bergau, Leonard, Malik, Marek, Vandenberk, Bert, Vos, Marc A., Schmidt, Georg, Merkely, Bela, Lubinski, Andrzej, Svetlosak, Martin, Braunschweig, Frieder, Harden, Markus, Zabel, Markus, Huikuri, Heikki V., Sticherling, Christian, Seegers, Joachim, Hasenfuß, Gerd, Munoz-Exposito, Pascal, Tichelbäcker, Tobias, Kirova, Aleksandra, Schlögl, Simon, Sritharan, Rajevaa, Jörß, Katharina, Macken, Jessica, Misdaq, Misbah, Rudolph, Kornelia, Bauer, Axel, Meyer-Zürn, Christine, Eick, Christian, rechts der Isar, Klinikum, Schmidt, Goerg, Müller, Alexander, Dommasch, Michael, Sinnecker, Daniel, Kääb, Stefan, Sinner, Moritz F., Dissmann, Rüdiger, Burmester, Ute, Behrens, Steffen, Gregor, Martina, Stefanow, Stefan, Rüb, Norman, Wolpert, Christian, Bimmel, Dieter, Lieberz, Christiane, Maier, Lars S., Schwinger, Robert H.G., Blaschke, Florian, Pieske, Burkert, Grönefeld, Gerian, Klein, Gunnar, Gardiwal, Ajmal, Szeplaki, Gabor, Perge, Peter, Szavits Nossan, Janko, Rotkvić, Luka, Pavlovic, Nikola, Manola, Sime, Vinter, Ozren, Benko, Ivica, Brusic, Sandro, Avdovic, Ervin, Klasan, Marina, Bakotic, Zoran, Anic, Ante, Jurisic, Zrinka, Kowalczyk, Emilia, Kucejko, Tomasz, Czechowska, Agnieszka, Wybor, Katarina, Cygankiewicz, Iwona, Ptaszyński, Pawel, Kasprzak, Jaroslaw, Qavoq, Dariusz, Guzik, Przemyslaw, Krauze, Tomasz, Sterlinski, Maciej, Hatala, Robert, Kaliska, Gabriela, Martinek, Jozef, Hastrup Svendsen, Jesper, Thamsborg, Karen, Hansen, Jim, Schloett-Hyldelund, Ida-Maria, Laage-Petersen, Julie, van Soest, Sofie, Flevari, Panayota, Katsaras, Dimitrios, Katsimardos, Andreas, Leftheriotis, Dionyssios, Papangelopoulou, Konstantinia, Varlamos, Charalambos, Traykov, Vassil, Velchev, Vasil, Iovev, Svetoslav, Shalganov, Tchavdar, Conen, David, Giesebart, Sarah, Novotny, Tomas, Kozak, Milan, Taborsky, Milos, Galuszka, Jan, Tuinenburg, Anton E., Wijers, Sofieke, Dunnink, Albert, Sprenkeler, David, Brugada, Josep, Arbelo, Elena, Trucco, Emilce, Vidorreta, Silvia, Kenttä, Tuomas, Huikuri, Pirkko, Koski, Päivi, Karlsson, Helena, Ersgaard, David, Platonov, Pyotr, Klingenheben, Thomas, and EU-CERT-ICD Investigators

Subjects
Male, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Ventricular Function, Left, DISEASE, Sudden cardiac death, Endocrinology, 0302 clinical medicine, Tachycardia, Medicine, FIBROSIS, Advanced and Specialised Nursing, 030212 general & internal medicine, Registries, 11 Medical and Health Sciences, RISK, Electroshock, OUTCOMES, Incidence (epidemiology), Incidence, Hazard ratio, ASSOCIATION, Middle Aged, Implantable cardioverter-defibrillator, 3. Good health, Defibrillators, Implantable, Diabetes and Metabolism, Primary Prevention, PRESERVED EJECTION FRACTION, Cardiology, Female, VENTRICULAR-FIBRILLATION, Life Sciences & Biomedicine, medicine.medical_specialty, 030209 endocrinology & metabolism, Lower risk, Sudden death, 03 medical and health sciences, Endocrinology & Metabolism, Diabetes mellitus, Internal medicine, Journal Article, Internal Medicine, Diabetes Mellitus, Humans, Aged, Retrospective Studies, Advanced and Specialized Nursing, Science & Technology, business.industry, Retrospective cohort study, medicine.disease, Death, Sudden, Cardiac, MYOCARDIAL-INFARCTION, ICD sudden death cardiomyopathy, business, SUDDEN CARDIAC DEATH, Diabetic Angiopathies, Follow-Up Studies
Abstract

OBJECTIVE Diabetes increases the risk of all-cause mortality and sudden cardiac death (SCD). The exact mechanisms leading to sudden death in diabetes are not well known. We compared the incidence of appropriate shocks and mortality in patients with versus without diabetes with a prophylactic implantable cardioverter defibrillator (ICD) included in the retrospective EU-CERT-ICD registry. RESEARCH DESIGN AND METHODS AND RESULTS A total of 3,535 patients from 12 European EU-CERT-ICD centers with a mean age of 63.7 ± 11.2 years (82% males) at the time of ICD implantation were included in the analysis. A total of 995 patients (28%) had a history of diabetes. All patients had an ICD implanted for primary SCD prevention. End points were appropriate shock and all-cause mortality. Mean follow-up time was 3.2 ± 2.3 years. Diabetes was associated with a lower risk of appropriate shocks (adjusted hazard ratio [HR] 0.77 [95% CI 0.62–0.96], P = 0.02). However, patients with diabetes had significantly higher mortality (adjusted HR 1.30 [95% CI 1.11–1.53], P = 0.001). CONCLUSIONS All-cause mortality is higher in patients with diabetes than in patients without diabetes with primary prophylactic ICDs. Subsequently, patients with diabetes have a lower incidence of appropriate ICD shocks, indicating that the excess mortality might not be caused primarily by ventricular tachyarrhythmias. These findings suggest a limitation of the potential of prophylactic ICD therapy to improve survival in patients with diabetes with impaired left ventricular function.

Published
2020

24. Age -Related Variations in Takotsubo Syndrome

Author

Cammann, Victoria L., Szawan, Konrad A., Stahli, Barbara E., Kato, Ken, Budnik, Monika, Wischnewsky, Manfred, Dreiding, Sara, Levinson, Rena A., Di Vece, Davide, Gili, Sebastiano, Citro, Rodolfo, Bossone, Eduardo, Neuhaus, Michael, Franke, Jennifer, Meder, Benjamin, Jaguszewski, Milosz, Noutsias, Michel, Knorr, Maike, Heiner, Susanne, D'Ascenzo, Fabrizio, Dichtl, Wolfgang, Burgdorf, Christof, Kherad, Behrouz, Tschope, Carsten, Sarcon, Annahita, Shinbane, Jerold, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Koenig, Wolfgang, Pott, Alexander, Meyer, Philippe, Roffi, Marco, Banning, Adrian, Wolfrum, Mathias, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Napp, L. Christian, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Chan, Christina, Bridgman, Paul, Beug, Daniel, Delmas, Clement, Lairez, Olivier, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, El-Battrawy, Ibrahim, Akin, Ibrahim, Polednikova, Karolina, Tous, Petr, Winchester, David E., Galuszka, Jan, Ukena, Christian, Poglajen, Gregor, Carrilho-Ferreira, Pedro, Hauck, Christian, Paolini, Carla, Bilato, Claudio, Kobayashi, Yoshio, Shoji, Toshihiro, Ishibashi, Iwao, Takahara, Masayuki, Himi, Toshiharu, Din, Jehangir, Al-Shammari, Ali, Prasad, Abhiram, Rihal, Charanjit S., Liu, Kan, Schulze, P. Christian, Bianco, Matteo, Jorg, Lucas, Rickli, Hans, Pestana, Goncalo, Nguyen, Thanh H., Bohm, Michael, Maier, Lars S., Pinto, Fausto J., Widimsky, Petr, Felix, Stephan B., Braun-Dullaeus, Ruediger C., Rottbauer, Wolfgang, Hasenfuss, Gerd, Pieske, Burkert M., Schunkert, Heribert, Borggrefe, Martin, Thiele, Holger, Bauersachs, Johann, Katus, Hugo A., Horowitz, John D., Di Mario, Carlo, Muenzel, Thomas, Crea, Filippo, Bax, Jeroen J., Luscher, Thomas F., Ruschitzka, Frank, Ghadri, Jelena R., Opolski, Grzegorz, Templin, Christian, Cammann, Victoria L., Szawan, Konrad A., Stahli, Barbara E., Kato, Ken, Budnik, Monika, Wischnewsky, Manfred, Dreiding, Sara, Levinson, Rena A., Di Vece, Davide, Gili, Sebastiano, Citro, Rodolfo, Bossone, Eduardo, Neuhaus, Michael, Franke, Jennifer, Meder, Benjamin, Jaguszewski, Milosz, Noutsias, Michel, Knorr, Maike, Heiner, Susanne, D'Ascenzo, Fabrizio, Dichtl, Wolfgang, Burgdorf, Christof, Kherad, Behrouz, Tschope, Carsten, Sarcon, Annahita, Shinbane, Jerold, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Koenig, Wolfgang, Pott, Alexander, Meyer, Philippe, Roffi, Marco, Banning, Adrian, Wolfrum, Mathias, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Napp, L. Christian, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Chan, Christina, Bridgman, Paul, Beug, Daniel, Delmas, Clement, Lairez, Olivier, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, El-Battrawy, Ibrahim, Akin, Ibrahim, Polednikova, Karolina, Tous, Petr, Winchester, David E., Galuszka, Jan, Ukena, Christian, Poglajen, Gregor, Carrilho-Ferreira, Pedro, Hauck, Christian, Paolini, Carla, Bilato, Claudio, Kobayashi, Yoshio, Shoji, Toshihiro, Ishibashi, Iwao, Takahara, Masayuki, Himi, Toshiharu, Din, Jehangir, Al-Shammari, Ali, Prasad, Abhiram, Rihal, Charanjit S., Liu, Kan, Schulze, P. Christian, Bianco, Matteo, Jorg, Lucas, Rickli, Hans, Pestana, Goncalo, Nguyen, Thanh H., Bohm, Michael, Maier, Lars S., Pinto, Fausto J., Widimsky, Petr, Felix, Stephan B., Braun-Dullaeus, Ruediger C., Rottbauer, Wolfgang, Hasenfuss, Gerd, Pieske, Burkert M., Schunkert, Heribert, Borggrefe, Martin, Thiele, Holger, Bauersachs, Johann, Katus, Hugo A., Horowitz, John D., Di Mario, Carlo, Muenzel, Thomas, Crea, Filippo, Bax, Jeroen J., Luscher, Thomas F., Ruschitzka, Frank, Ghadri, Jelena R., Opolski, Grzegorz, and Templin, Christian

Published
2020

25. Coexistence and outcome of coronary artery disease in Takotsubo syndrome

Author

Napp, L. Christian, Cammann, Victoria L., Jaguszewski, Milosz, Szawan, Konrad A., Wischnewsky, Manfred, Gili, Sebastiano, Knorr, Maike, Heiner, Susanne, Citro, Rodolfo, Bossone, Eduardo, D'Ascenzo, Fabrizio, Neuhaus, Michael, Franke, Jennifer, Sorici-Barb, Ioana, Noutsias, Michel, Burgdorf, Christof, Koenig, Wolfgang, Kherad, Behrouz, Sarcon, Annahita, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Pott, Alexander, Meyer, Philippe, Arroja, Jose D., Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Hauck, Christian, Paolini, Carla, Bilato, Claudio, Imori, Yoichi, Kato, Ken, Kobayashi, Yoshio, Opolski, Grzegorz, Budnik, Monika, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Dichtl, Wolfgang, Chan, Christina, Bridgman, Paul, Beug, Daniel, Delmas, Clement, Lairez, Olivier, El-Battrawy, Ibrahim, Akin, Ibrahim, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Horowitz, John D., Polednikova, Karolina, Tousek, Petr, Widimsky, Petr, Winchester, David E., Galuszka, Jan, Ukena, Christian, Poglajen, Gregor, Carrilho-Ferreira, Pedro, Di Mario, Carlo, Prasad, Abhiram, Rihal, Charanjit S., Schulze, P. Christian, Bianco, Matteo, Crea, Filippo, Borggrefe, Martin, Maier, Lars S., Pinto, Fausto J., Braun-Dullaeus, Ruediger C., Rottbauer, Wolfgang, Katus, Hugo A., Hasenfuss, Gerd, Tschoepe, Carsten, Pieske, Burkert M., Thiele, Holger, Schunkert, Heribert, Boehm, Michael, Felix, Stephan B., Muenzel, Thomas, Bax, Jeroen J., Bauersachs, Johann, Braunwald, Eugene, Luescher, Thomas F., Ruschitzka, Frank, Ghadri, Jelena R., Templin, Christian, Napp, L. Christian, Cammann, Victoria L., Jaguszewski, Milosz, Szawan, Konrad A., Wischnewsky, Manfred, Gili, Sebastiano, Knorr, Maike, Heiner, Susanne, Citro, Rodolfo, Bossone, Eduardo, D'Ascenzo, Fabrizio, Neuhaus, Michael, Franke, Jennifer, Sorici-Barb, Ioana, Noutsias, Michel, Burgdorf, Christof, Koenig, Wolfgang, Kherad, Behrouz, Sarcon, Annahita, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Pott, Alexander, Meyer, Philippe, Arroja, Jose D., Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Hauck, Christian, Paolini, Carla, Bilato, Claudio, Imori, Yoichi, Kato, Ken, Kobayashi, Yoshio, Opolski, Grzegorz, Budnik, Monika, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Dichtl, Wolfgang, Chan, Christina, Bridgman, Paul, Beug, Daniel, Delmas, Clement, Lairez, Olivier, El-Battrawy, Ibrahim, Akin, Ibrahim, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Horowitz, John D., Polednikova, Karolina, Tousek, Petr, Widimsky, Petr, Winchester, David E., Galuszka, Jan, Ukena, Christian, Poglajen, Gregor, Carrilho-Ferreira, Pedro, Di Mario, Carlo, Prasad, Abhiram, Rihal, Charanjit S., Schulze, P. Christian, Bianco, Matteo, Crea, Filippo, Borggrefe, Martin, Maier, Lars S., Pinto, Fausto J., Braun-Dullaeus, Ruediger C., Rottbauer, Wolfgang, Katus, Hugo A., Hasenfuss, Gerd, Tschoepe, Carsten, Pieske, Burkert M., Thiele, Holger, Schunkert, Heribert, Boehm, Michael, Felix, Stephan B., Muenzel, Thomas, Bax, Jeroen J., Bauersachs, Johann, Braunwald, Eugene, Luescher, Thomas F., Ruschitzka, Frank, Ghadri, Jelena R., and Templin, Christian

Abstract

Aims Takotsubo syndrome (US) is an acute heart failure syndrome, which shares many features with acute coronary syndrome (ACS). Although TTS was initially described with angiographically normal coronary arteries, smaller studies recently indicated a potential coexistence of coronary artery disease (CAD) in US patients. This study aimed to determine the coexistence, features, and prognostic role of CAD in a large cohort of patients with US. Methods and results Coronary anatomy and CAD were studied in patients diagnosed with US. Inclusion criteria were compliance with the International Takotsubo Diagnostic Criteria for TTS, and availability of original coronary angiographies with ventriculography performed during the acute phase. Exclusion criteria were missing views, poor quality of angiography loops, and angiography without ventriculography. A total of 1016 US patients were studied. Of those, 23.0% had obstructive CAD, 41.2% had non -obstructive CAD, and 35.7% had angiographically normal coronary arteries. A total of 47 patients (4.6%) underwent percutaneous coronary intervention, and 3 patients had acute and 8 had chronic coronary artery occlusion concomitant with US, respectively. The presence of CAD was associated with increased incidence of shock, ventilation, and death from any cause. After adjusting for confounders, the presence of obstructive CAD was associated with mortality at 30 days. Takotsubo syndrome patients with obstructive CAD were at comparable risk for shock and death and nearly at twice the risk for ventilation compared to an age- and sex-matched ACS cohort. Conclusions Coronary artery disease frequently coexists in US patients, presents with the whole spectrum of coronary pathology including acute coronary occlusion, and is associated with adverse outcome.

Published
2020

26. Coexistence and outcome of coronary artery disease in Takotsubo syndrome

Author

Napp, L Christian, primary, Cammann, Victoria L, additional, Jaguszewski, Milosz, additional, Szawan, Konrad A, additional, Wischnewsky, Manfred, additional, Gili, Sebastiano, additional, Knorr, Maike, additional, Heiner, Susanne, additional, Citro, Rodolfo, additional, Bossone, Eduardo, additional, D’Ascenzo, Fabrizio, additional, Neuhaus, Michael, additional, Franke, Jennifer, additional, Sorici-Barb, Ioana, additional, Noutsias, Michel, additional, Burgdorf, Christof, additional, Koenig, Wolfgang, additional, Kherad, Behrouz, additional, Sarcon, Annahita, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Pott, Alexander, additional, Meyer, Philippe, additional, Arroja, Jose D, additional, Banning, Adrian, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A, additional, Vasankari, Tuija, additional, Airaksinen, K E Juhani, additional, Hauck, Christian, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Imori, Yoichi, additional, Kato, Ken, additional, Kobayashi, Yoshio, additional, Opolski, Grzegorz, additional, Budnik, Monika, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Dichtl, Wolfgang, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, El-Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, Horowitz, John D, additional, Polednikova, Karolina, additional, Tousek, Petr, additional, Widimský, Petr, additional, Winchester, David E, additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Carrilho-Ferreira, Pedro, additional, Di Mario, Carlo, additional, Prasad, Abhiram, additional, Rihal, Charanjit S, additional, Schulze, P Christian, additional, Bianco, Matteo, additional, Crea, Filippo, additional, Borggrefe, Martin, additional, Maier, Lars S, additional, Pinto, Fausto J, additional, Braun-Dullaeus, Ruediger C, additional, Rottbauer, Wolfgang, additional, Katus, Hugo A, additional, Hasenfuß, Gerd, additional, Tschöpe, Carsten, additional, Pieske, Burkert M, additional, Thiele, Holger, additional, Schunkert, Heribert, additional, Böhm, Michael, additional, Felix, Stephan B, additional, Münzel, Thomas, additional, Bax, Jeroen J, additional, Bauersachs, Johann, additional, Braunwald, Eugene, additional, Lüscher, Thomas F, additional, Ruschitzka, Frank, additional, Ghadri, Jelena R, additional, and Templin, Christian, additional

Published
2020
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27. Age-Related Variations in Takotsubo Syndrome

Author

Cammann, Victoria L., primary, Szawan, Konrad A., additional, Stähli, Barbara E., additional, Kato, Ken, additional, Budnik, Monika, additional, Wischnewsky, Manfred, additional, Dreiding, Sara, additional, Levinson, Rena A., additional, Di Vece, Davide, additional, Gili, Sebastiano, additional, Citro, Rodolfo, additional, Bossone, Eduardo, additional, Neuhaus, Michael, additional, Franke, Jennifer, additional, Meder, Benjamin, additional, Jaguszewski, Miłosz, additional, Noutsias, Michel, additional, Knorr, Maike, additional, Heiner, Susanne, additional, D’Ascenzo, Fabrizio, additional, Dichtl, Wolfgang, additional, Burgdorf, Christof, additional, Kherad, Behrouz, additional, Tschöpe, Carsten, additional, Sarcon, Annahita, additional, Shinbane, Jerold, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Koenig, Wolfgang, additional, Pott, Alexander, additional, Meyer, Philippe, additional, Roffi, Marco, additional, Banning, Adrian, additional, Wolfrum, Mathias, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A., additional, Vasankari, Tuija, additional, Airaksinen, K.E. Juhani, additional, Napp, L. Christian, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, El-Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Poledniková, Karolina, additional, Toušek, Petr, additional, Winchester, David E., additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Carrilho-Ferreira, Pedro, additional, Hauck, Christian, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Kobayashi, Yoshio, additional, Shoji, Toshihiro, additional, Ishibashi, Iwao, additional, Takahara, Masayuki, additional, Himi, Toshiharu, additional, Din, Jehangir, additional, Al-Shammari, Ali, additional, Prasad, Abhiram, additional, Rihal, Charanjit S., additional, Liu, Kan, additional, Schulze, P. Christian, additional, Bianco, Matteo, additional, Jörg, Lucas, additional, Rickli, Hans, additional, Pestana, Gonçalo, additional, Nguyen, Thanh H., additional, Böhm, Michael, additional, Maier, Lars S., additional, Pinto, Fausto J., additional, Widimský, Petr, additional, Felix, Stephan B., additional, Braun-Dullaeus, Ruediger C., additional, Rottbauer, Wolfgang, additional, Hasenfuß, Gerd, additional, Pieske, Burkert M., additional, Schunkert, Heribert, additional, Borggrefe, Martin, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Katus, Hugo A., additional, Horowitz, John D., additional, Di Mario, Carlo, additional, Münzel, Thomas, additional, Crea, Filippo, additional, Bax, Jeroen J., additional, Lüscher, Thomas F., additional, Ruschitzka, Frank, additional, Ghadri, Jelena R., additional, Opolski, Grzegorz, additional, and Templin, Christian, additional

Published
2020
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28. Clinical Predictors and Prognostic Impact of Recovery of Wall Motion Abnormalities in Takotsubo Syndrome: Results From the International Takotsubo Registry

Author

Jurisic, Stjepan, Gili, Sebastiano, Cammann, Victoria L., Kato, Ken, Szawan, Konrad A., D'Ascenzo, Fabrizio, Jaguszewski, Milosz, Bossone, Eduardo, Citro, Rodolfo, Sarcon, Annahita, Napp, L. Christian, Franke, Jennifer, Noutsias, Michel, Knorr, Maike, Heiner, Susanne, Burgdorf, Christof, Koenig, Wolfgang, Pott, Alexander, Kherad, Behrouz, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Meyer, Philippe, Arroja, Jose David, Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Dworakowski, Rafal, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Dichtl, Wolfgang, Chan, Christina, Bridgman, Paul, Beug, Daniel, Delmas, Clement, Lairez, Olivier, Kozel, Martin, Tousek, Petr, Winchester, David E., Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, El-Battrawy, Ibrahim, Akin, Ibrahim, Galuszka, Jan, Ukena, Christian, Poglajen, Gregor, Paolini, Carla, Bilato, Claudio, Carrilho-Ferreira, Pedro, Pinto, Fausto J., Opolski, Grzegorz, MacCarthy, Philip, Kobayashi, Yoshio, Prasad, Abhiram, Rihal, Charanjit S., Widimsky, Petr, Horowitz, John D., Di Mario, Carlo, Crea, Filippo, Tschope, Carsten, Pieske, Burkert M., Hasenfuss, Gerd, Rottbauer, Wolfgang, Braun-Dullaeus, Ruediger C., Felix, Stephan B., Borggrefe, Martin, Thiele, Holger, Bauersachs, Johann, Katus, Hugo A., Schunkert, Heribert, Muenzel, Thomas, Bohm, Michael, Bax, Jeroen J., Luscher, Thomas F., Ruschitzka, Frank, Ghadri, Jelena R., Templin, Christian, Jurisic, Stjepan, Gili, Sebastiano, Cammann, Victoria L., Kato, Ken, Szawan, Konrad A., D'Ascenzo, Fabrizio, Jaguszewski, Milosz, Bossone, Eduardo, Citro, Rodolfo, Sarcon, Annahita, Napp, L. Christian, Franke, Jennifer, Noutsias, Michel, Knorr, Maike, Heiner, Susanne, Burgdorf, Christof, Koenig, Wolfgang, Pott, Alexander, Kherad, Behrouz, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Meyer, Philippe, Arroja, Jose David, Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Dworakowski, Rafal, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Dichtl, Wolfgang, Chan, Christina, Bridgman, Paul, Beug, Daniel, Delmas, Clement, Lairez, Olivier, Kozel, Martin, Tousek, Petr, Winchester, David E., Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, El-Battrawy, Ibrahim, Akin, Ibrahim, Galuszka, Jan, Ukena, Christian, Poglajen, Gregor, Paolini, Carla, Bilato, Claudio, Carrilho-Ferreira, Pedro, Pinto, Fausto J., Opolski, Grzegorz, MacCarthy, Philip, Kobayashi, Yoshio, Prasad, Abhiram, Rihal, Charanjit S., Widimsky, Petr, Horowitz, John D., Di Mario, Carlo, Crea, Filippo, Tschope, Carsten, Pieske, Burkert M., Hasenfuss, Gerd, Rottbauer, Wolfgang, Braun-Dullaeus, Ruediger C., Felix, Stephan B., Borggrefe, Martin, Thiele, Holger, Bauersachs, Johann, Katus, Hugo A., Schunkert, Heribert, Muenzel, Thomas, Bohm, Michael, Bax, Jeroen J., Luscher, Thomas F., Ruschitzka, Frank, Ghadri, Jelena R., and Templin, Christian

Abstract

Background-Left ventricular (LV) recovery in takotsubo syndrome (TTS) occurs over a wide-ranging interval, varying from hours to weeks. We sought to investigate the clinical predictors and prognostic impact of recovery time for TTS patients. Methods and Results-TTS patients from the International Takotsubo Registry were included in this study. Cut-off for early LV recovery was determined to be 10 days after the acute event. Multivariable logistic regression was used to assess factors associated with the absence of early recovery. In-hospital outcomes and 1-year mortality were compared for patients with versus without early recovery. We analyzed 406 patients with comprehensive and serial imaging data regarding time to recovery. Of these, 191 (47.0%) had early LV recovery and 215 (53.0%) demonstrated late LV improvement. Patients without early recovery were more often male (12.6% versus 5.2%; P=0.011) and presented more frequently with typical TTS (76.3% versus 67.0%, P=0.040). Cardiac and inflammatory markers were higher in patients without early recovery than in those with early recovery. Patients without early recovery showed unfavorable 1-year outcome compared with patients with early recovery (P=0.003). On multiple logistic regression, male sex, LV ejection fraction <45%, and acute neurologic disorders were associated with the absence of early recovery. Conclusions-TTS patients without early LV recovery have different clinical characteristics and less favorable 1-year outcome compared with patients with early recovery. The factors associated with the absence of early recovery included male sex, reduced LV ejection fraction, and acute neurologic events.

Published
2019

30. Clinical Predictors and Prognostic Impact of Recovery of Wall Motion Abnormalities in Takotsubo Syndrome: Results From the International Takotsubo Registry

Author

Jurisic, Stjepan, primary, Gili, Sebastiano, additional, Cammann, Victoria L., additional, Kato, Ken, additional, Szawan, Konrad A., additional, D'Ascenzo, Fabrizio, additional, Jaguszewski, Milosz, additional, Bossone, Eduardo, additional, Citro, Rodolfo, additional, Sarcon, Annahita, additional, Napp, L. Christian, additional, Franke, Jennifer, additional, Noutsias, Michel, additional, Knorr, Maike, additional, Heiner, Susanne, additional, Burgdorf, Christof, additional, Koenig, Wolfgang, additional, Pott, Alexander, additional, Kherad, Behrouz, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Meyer, Philippe, additional, Arroja, Jose David, additional, Banning, Adrian, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A., additional, Vasankari, Tuija, additional, Airaksinen, K. E. Juhani, additional, Dworakowski, Rafal, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Dichtl, Wolfgang, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, Kozel, Martin, additional, Tousek, Petr, additional, Winchester, David E., additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, El‐Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Carrilho‐Ferreira, Pedro, additional, Pinto, Fausto J., additional, Opolski, Grzegorz, additional, MacCarthy, Philip, additional, Kobayashi, Yoshio, additional, Prasad, Abhiram, additional, Rihal, Charanjit S., additional, Widimský, Petr, additional, Horowitz, John D., additional, Di Mario, Carlo, additional, Crea, Filippo, additional, Tschöpe, Carsten, additional, Pieske, Burkert M., additional, Hasenfuß, Gerd, additional, Rottbauer, Wolfgang, additional, Braun‐Dullaeus, Ruediger C., additional, Felix, Stephan B., additional, Borggrefe, Martin, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Katus, Hugo A., additional, Schunkert, Heribert, additional, Münzel, Thomas, additional, Böhm, Michael, additional, Bax, Jeroen J., additional, Lüscher, Thomas F., additional, Ruschitzka, Frank, additional, Ghadri, Jelena R., additional, and Templin, Christian, additional

Published
2019
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31. Present criteria for prophylactic ICD implantation: Insights from the EU-CERT-ICD (Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in EUrope) project

Author

Zabel, Markus, primary, Schlögl, Simon, additional, Lubinski, Andrzej, additional, Svendsen, Jesper Hastrup, additional, Bauer, Axel, additional, Arbelo, Elena, additional, Brusich, Sandro, additional, Conen, David, additional, Cygankiewicz, Iwona, additional, Dommasch, Michael, additional, Flevari, Panagiota, additional, Galuszka, Jan, additional, Hansen, Jim, additional, Hasenfuß, Gerd, additional, Hatala, Robert, additional, Huikuri, Heikki V., additional, Kenttä, Tuomas, additional, Kucejko, Tomasz, additional, Haarmann, Helge, additional, Harden, Markus, additional, Iovev, Svetoslav, additional, Kääb, Stefan, additional, Kaliska, Gabriela, additional, Katsimardos, Andreas, additional, Kasprzak, Jaroslaw D., additional, Qavoq, Dariusz, additional, Lüthje, Lars, additional, Malik, Marek, additional, Novotný, Tomáš, additional, Pavlović, Nikola, additional, Perge, Peter, additional, Röver, Christian, additional, Schmidt, Georg, additional, Shalganov, Tchavdar, additional, Sritharan, Rajeeva, additional, Svetlosak, Martin, additional, Sallo, Zoltan, additional, Szavits-Nossan, Janko, additional, Traykov, Vassil, additional, Vandenberk, Bert, additional, Velchev, Vasil, additional, Vos, Marc A., additional, Willich, Stefan N., additional, Friede, Tim, additional, Willems, Rik, additional, Merkely, Béla, additional, and Sticherling, Christian, additional

Published
2019
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32. Prediction of mortality benefit based on periodic repolarisation dynamics in patients undergoing prophylactic implantation of a defibrillator: a prospective, controlled, multicentre cohort study

Author

Bauer, Axel, primary, Klemm, Mathias, additional, Rizas, Konstantinos D, additional, Hamm, Wolfgang, additional, von Stülpnagel, Lukas, additional, Dommasch, Michael, additional, Steger, Alexander, additional, Lubinski, Andrezej, additional, Flevari, Panagiota, additional, Harden, Markus, additional, Friede, Tim, additional, Kääb, Stefan, additional, Merkely, Bela, additional, Sticherling, Christian, additional, Willems, Rik, additional, Huikuri, Heikki, additional, Malik, Marek, additional, Schmidt, Georg, additional, Zabel, Markus, additional, Merkely, Béla, additional, Perge, Peter, additional, Sallo, Zoltan, additional, Szeplaki, Gabor, additional, Lüthje, Lars, additional, Schlögl, Simon, additional, Haarmann, Helge, additional, Bergau, Leonard, additional, Seegers, Joachim, additional, Hasenfuß, Gerd, additional, Munoz-Exposito, Pascal, additional, Tichelbäcker, Tobias, additional, Kirova, Aleksandra, additional, Hnatkova, Katerina, additional, Vos, Marc, additional, Willich, Stefan N., additional, Reinhold, Thomas, additional, Vandenberk, Bert, additional, Klinika, Magdalena, additional, Toplice, Krapinske, additional, Flevari, Panayota, additional, Katsimardos, Andreas, additional, Katsaras, Dimitrios, additional, Hatala, Robert, additional, Svetlosak, Martin, additional, Lubinski, Andrzej, additional, Kuczejko, Tomasz, additional, Hansen, Jim, additional, Conen, David, additional, Milosrdnice, Sestre, additional, Pavlović, Nikola, additional, Manola, Šime, additional, Vinter, Ozren, additional, Benko, Ivica, additional, Tuinenburg, Anton, additional, Bauer, Axel, additional, Meyer-Zürn, Christine, additional, Eick, Christian, additional, Hastrup, Jesper, additional, Brugada, Josep, additional, Arbelo, Elena, additional, Kaliska, Gabriela, additional, Martinek, Jozef, additional, Sinner, Moritz F., additional, Rizas, Konstantinos D., additional, Vdovin, Nikolay, additional, Cygankiewicz, Iwona, additional, Ptaszynski, Pawel, additional, Kaczmarek, Krzysztof, additional, Poddebska, Izabela, additional, Iovev, Svetoslav, additional, Novotný, Tomáš, additional, Kozak, Milan, additional, Kenttä, Tuomas, additional, Pelli, Ari, additional, Kasprzak, Jaroslaw D., additional, Qavoq, Dariusz, additional, Brusich, Sandro, additional, Avdovic, Ervin, additional, Klasan, Marina, additional, Galuszka, Jan, additional, Taborsky, Milos, additional, Velchev, Vasil, additional, Dissmann, Rüdiger, additional, Guzik, Przemysław, additional, Bimmel, Dieter, additional, Lieberz, Christiane, additional, Stefanow, Stefan, additional, Rüb, Norman, additional, Wolpert, Christian, additional, Maier, Lars S., additional, Behrens, Steffen, additional, Jurisic, Zrinka, additional, Braunschweig, Frieder, additional, Blaschke, Florian, additional, Pieske, Burkert, additional, Bakotic, Zoran, additional, Anic, Ante, additional, Schwinger, Robert H.G., additional, and Platonov, Pyotr, additional

Published
2019
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33. Prediction of short‐ and long‐term mortality in takotsubo syndrome: the InterTAK Prognostic Score

Author

Wischnewsky, Manfred B., primary, Candreva, Alessandro, additional, Bacchi, Beatrice, additional, Cammann, Victoria L., additional, Kato, Ken, additional, Szawan, Konrad A., additional, Gili, Sebastiano, additional, D'Ascenzo, Fabrizio, additional, Dichtl, Wolfgang, additional, Citro, Rodolfo, additional, Bossone, Eduardo, additional, Neuhaus, Michael, additional, Franke, Jennifer, additional, Sorici‐Barb, Ioana, additional, Jaguszewski, Milosz, additional, Noutsias, Michel, additional, Knorr, Maike, additional, Heiner, Susanne, additional, Burgdorf, Christof, additional, Kherad, Behrouz, additional, Tschöpe, Carsten, additional, Sarcon, Annahita, additional, Shinbane, Jerold, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Koenig, Wolfgang, additional, Pott, Alexander, additional, Meyer, Philippe, additional, Arroja, Jose David, additional, Banning, Adrian, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A., additional, Vasankari, Tuija, additional, Airaksinen, K.E. Juhani, additional, Napp, L. Christian, additional, Budnik, Monika, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, El‐Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, Kozel, Martin, additional, Tousek, Petr, additional, Winchester, David E., additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Carrilho‐Ferreira, Pedro, additional, Hauck, Christian, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Prasad, Abhiram, additional, Rihal, Charanjit S., additional, Liu, Kan, additional, Schulze, P. Christian, additional, Bianco, Matteo, additional, Jörg, Lucas, additional, Rickli, Hans, additional, Nguyen, Thanh H., additional, Kobayashi, Yoshio, additional, Böhm, Michael, additional, Maier, Lars S., additional, Pinto, Fausto J., additional, Widimský, Petr, additional, Borggrefe, Martin, additional, Felix, Stephan B., additional, Opolski, Grzegorz, additional, Braun‐Dullaeus, Ruediger C., additional, Rottbauer, Wolfgang, additional, Hasenfuß, Gerd, additional, Pieske, Burkert M., additional, Schunkert, Heribert, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Katus, Hugo A., additional, Horowitz, John, additional, Di Mario, Carlo, additional, Münzel, Thomas, additional, Crea, Filippo, additional, Bax, Jeroen J., additional, Lüscher, Thomas F., additional, Ruschitzka, Frank, additional, Ghadri, Jelena R., additional, and Templin, Christian, additional

Published
2019
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36. 176-79: Lipidomic analysis in patients with cardiac arrhythmias

Author

Galuszka, Jan, primary, Vostalova, Jitka, additional, Galuszkova, Dana, additional, Blanka, Cervena, additional, Simanek, Vilim, additional, Taborsky, Milos, additional, Holcapek, Michal, additional, Vrbkova, Jana, additional, Cifkova, Eva, additional, and Lisa, Miroslav, additional

Published
2016
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37. Self care in patients with chronic heart failure. Pilot study - self care includes problems

Author

Halmo, Renata, Galuszka, Jan, Langová, Kateřina, Galuszková, Dana, Halmo, Renata, Galuszka, Jan, Langová, Kateřina, and Galuszková, Dana

Abstract

Aim. The goal of this pilot study was to define the scope of therapeutic self-care demand in heart failure (HF) patients according to the concepts of self-care postulated by D.E. Orem and to determine the level of problems experienced and self-care in these patients. Methods. A questionnaire consisting of 7 areas with closed format questions was developed according to the definition. The level of patient problems and level of self-care actions were mapped in each area. The questionnaire was distributed at the hospital outpatient clinic. The study group consisted of 47 heart failure patients (14 women) with following characteristics: average age 68 years, average BMI 29.4, resynchronization therapy 21%, hypertension 69.8%, diabetes mellitus 25.6%, coronary artery disease 46.5%, dilated cardiomyopathy 46.5%, obesity 46.5%, smoking history 39.5% (present and past smoking together), other cardiac disease 16.28%, condition after myocardial infarction 27.8% (NYHA II 41%, NYHA III 56.8%, NYHA IV 2.2%). Results. The greatest problems were in the area of physical activity, sleep and fatigue, the least were in the area of chest pain and blood circulation. The greatest self-care agency was shown in the area of managing problems with physical activities and sleep, the lowest in the area of liquid intake and output. In the patients' subjective opinion, fatigue and sleep problems had the greatest impact on the quality of life. There were no substantial differences in either area based on gender. Conclusions. The data can serve as a foundation for modifying the extent and structure of patient education for more comprehensive and more effective out-patient treatment of HF.

Published
2015

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