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1. Conservative Surgery in cT4 Breast Cancer: Single-Center Experience in the Neoadjuvant Setting

Author

Franco, Alessio, Di Leone, Alba, Fabi, A., Belli, Paolo, Carbognin, L., Gambaro, Elisabetta, Marazzi, Fabio, Mason, Elena Jane, Mule, A., Orlandi, Armando, Palazzo, Antonella, Paris, Ida, Rossi, A., Scardina, L., Terribile, Daniela Andreina, Tiberi, G., Giannarelli, Diana, Scambia, Giovanni, Masetti, Riccardo, Franceschini, Gianluca, Franco A., Di Leone A., Belli P. (ORCID:0000-0001-7979-2466), Gambaro E., Marazzi F., Mason E. J., Orlandi A. (ORCID:0000-0001-5253-4678), Palazzo A., Paris I., Terribile D. A. (ORCID:0000-0002-3511-0010), Giannarelli D., Scambia G. (ORCID:0000-0003-2758-1063), Masetti R. (ORCID:0000-0002-7520-9111), Franceschini G. (ORCID:0000-0002-2950-3395), Franco, Alessio, Di Leone, Alba, Fabi, A., Belli, Paolo, Carbognin, L., Gambaro, Elisabetta, Marazzi, Fabio, Mason, Elena Jane, Mule, A., Orlandi, Armando, Palazzo, Antonella, Paris, Ida, Rossi, A., Scardina, L., Terribile, Daniela Andreina, Tiberi, G., Giannarelli, Diana, Scambia, Giovanni, Masetti, Riccardo, Franceschini, Gianluca, Franco A., Di Leone A., Belli P. (ORCID:0000-0001-7979-2466), Gambaro E., Marazzi F., Mason E. J., Orlandi A. (ORCID:0000-0001-5253-4678), Palazzo A., Paris I., Terribile D. A. (ORCID:0000-0002-3511-0010), Giannarelli D., Scambia G. (ORCID:0000-0003-2758-1063), Masetti R. (ORCID:0000-0002-7520-9111), and Franceschini G. (ORCID:0000-0002-2950-3395)

Abstract

Background: The diffusion of screening programs has resulted in a decrease of cT4 breast cancer diagnosis. The standard care for cT4 was neoadjuvant chemotherapy (NA), surgery, and locoregional or adjuvant systemic therapies. NA allows two outcomes: 1. improve survival rates, and 2. de-escalation of surgery. This de-escalation has allowed the introduction of conservative breast surgery (CBS). We evaluate the possibility of submitting cT4 patients to CBS instead of radical breast surgery (RBS) by assessing the risk of locoregional disease-free survival, (LR-DFS) distant disease-free survival (DDFS), and overall survival (OS). Methods: This monocentric, retrospective study evaluated cT4 patients submitted to NA and surgery between January 2014 and July 2021. The study population included patients undergoing CBS or RBS without immediate reconstruction. Survival curves were obtained using the Kaplan-Meyer method and compared using a Log Rank test. Results: At a follow-up of 43.7 months, LR-DFS was 70% and 75.9%, respectively, in CBS and RBS (p = 0.420). DDFS was 67.8% and 29.7%, respectively, (p = 0.122). OS was 69.8% and 59.8%, respectively, (p = 0.311). Conclusions: In patients with major or complete response to NA, CBS can be considered a safe alternative to RBS in the treatment of cT4a-d stage. In patients with poor response to NA, RBS remained the best surgical choice.

Published
2023

2. Genome-wide association study detected novel susceptibility genes for social cognition impairment in people with schizophrenia

Author

Gennarelli, M., Monteleone, P., Minelli, A., Monteleone, A. M., Rossi, A., Rocca, P., Bertolino, A., Aguglia, E., Amore, M., Bellino, S., Bellomo, A., Biondi, M., Bucci, P., Carpiniello, B., Cascino, G., Cuomo, A., Dell'Osso, L., di Giannantonio, M., Giordano, G. M., Marchesi, C., Oldani, L., Pompili, M., Roncone, R., Rossi, R., Siracusano, A., Tenconi, E., Vita, A., Zeppegno, P., Galderisi, S., Maj, M., Corrivetti, G., Del Buono, G., Torretta, S., Calia, V., Raio, A., Barlati, S., Deste, G., Magri, C., Valsecchi, P., Pinna, F., Muscas, M., Marras, L., Piegari, G., Giuliani, L., Brando, F., Coccia, C., Concerto, C., Poli, L. F., Surace, T., Martinotti, G., Pettorruso, M., Fraticelli, S., Altamura, M., Pasquale Tortorelli, F. M., Mollica, A., Calcagno, P., Murri, M. B., Serafini, G., Pacitti, F., Socci, V., Lucaselli, A., Giusti, L., Mammarella, S., Bianchini, V., Gramaglia, C., Gambaro, E., Martelli, M., Favaro, A., Meneguzzo, P., Collantoni, E., Tonna, M., Ossola, P., Gerra, M. L., Carmassi, C., Carpita, B., Cremone, I. M., Comparelli, A., Brugnoli, R., Corigliano, V., Fagiolini, A., Bolognesi, S., Goracci, A., Di Lorenzo, G., Ribolsi, M., Niolu, C., Bozzatello, P., Brasso, C., Montemagni, C., Buzzanca, A., Di Fabio, F., Girardi, N., Gennarelli, Massimo, Monteleone, Palmiero, Minelli, Alessandra, Monteleone, Alessio Maria, Rossi, Alessandro, Rocca, Paola, Bertolino, Alessandro, Aguglia, Eugenio, Amore, Mario, Bellino, Silvio, Bellomo, Antonello, Biondi, Massimo, Bucci, Paola, Carpiniello, Bernardo, Cascino, Giammarco, Cuomo, Alessandro, Dell'Osso, Liliana, di Giannantonio, Massimo, Giordano, Giulia Maria, Marchesi, Carlo, Oldani, Lucio, Pompili, Maurizio, Roncone, Rita, Rossi, Rodolfo, Siracusano, Alberto, Tenconi, Elena, Vita, Antonio, Zeppegno, Patrizia, Galderisi, Silvana, and Maj, Mario

Subjects
Treatment outcome, GWAS, Social cognition, TMEM74, meta-analysis, schizophrenia, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Membrane Proteins, Polymorphism, Single Nucleotide, Schizophrenia, Social Cognition, Susceptibility gene, Genome-wide association study, Biology, Affect (psychology), meta-analysi, 03 medical and health sciences, 0302 clinical medicine, medicine, SNP, Polymorphism, Biological Psychiatry, Genetics, Single Nucleotide, medicine.disease, 030227 psychiatry, Psychiatry and Mental health, Settore MED/25, Meta-analysis
Abstract

Objectives People with schizophrenia (SCZ) present serious and generalised deficits in social cognition (SC), which affect negatively patients' functioning and treatment outcomes. The genetic background of SC has been investigated in disorders other than SCZ providing weak and sparse results. Thus, our aim was to explore possible genetic correlates of SC dysfunctions in SCZ patients with a genome-wide study (GWAS) approach. Methods We performed a GWAS meta-analysis of data coming from two cohorts made of 242 and 160 SCZ patients, respectively. SC was assessed with different tools in order to cover its different domains. Results We found GWAS significant association between the TMEM74 gene and the patients' ability in social inference as assessed by The Awareness of Social Inference Test; this association was confirmed by both SNP-based analysis (lead SNP rs3019332 p-value = 5.24 × 10-9) and gene-based analysis (p-value = 1.09 × 10-7). Moreover, suggestive associations of other genes with different dimensions of SC were also found. Conclusions Our study shows for the first time GWAS significant or suggestive associations of some gene variants with SC domains in people with SCZ. These findings should stimulate further studies to characterise the genetic underpinning of SC dysfunctions in SCZ.

Published
2022

3. Factors Associated With Real-Life Functioning in Persons With Schizophrenia in a 4-Year Follow-up Study of the Italian Network for Research on Psychoses

Author

Mucci, A., Galderisi, S., Gibertoni, D., Rossi, A., Rocca, P., Bertolino, A., Aguglia, E., Amore, M., Bellomo, A., Biondi, M., Blasi, G., Brasso, C., Bucci, P., Carpiniello, B., Cuomo, A., Dell'Osso, L., Giordano, G. M., Marchesi, C., Monteleone, P., Niolu, C., Oldani, L., Pettorruso, M., Pompili, M., Roncone, R., Rossi, R., Tenconi, E., Vita, A., Zeppegno, P., Maj, M., Piegari, G., Aiello, C., Brando, F., Giuliani, L., Palumbo, D., Coccia, C., Papalino, M., Calia, V., Romano, R., Barlati, S., Deste, G., Valsecchi, P., Pinna, F., Lai, A., Lostia di Santa Sofia, S., Salvina Signorelli, M., Fusar Poli, L., Surace, T., Martinotti, G., Montemitro, C., Fraticelli, S., Altamura, M., Angelini, E., Elia, A., Calcagno, P., Belvederi Murri, M., Cattedra, S., Pacitti, F., Talevi, D., Socci, V., Giusti, L., Salza, A., Mammarella, S., de Bartolomeis, A., Favaro, A., Collantoni, E., Meneguzzo, P., Tonna, M., Ossola, P., Gerra, M. L., Gramaglia, C., Binda, V., Gambaro, E., Carmassi, C., Carpita, B., Cremone, I. M., Corrivetti, G., Cascino, G., Del Buono, G., Brugnoli, R., Comparelli, A., Corigliano, V., Buzzanca, A., Gerardi, N., Frascarelli, M., Fagiolini, A., Goracci, A., Bolognesi, S., Siracusano, A., Di Lorenzo, G., Ribolsi, M., Montemagni, C., Riccardi, C., Del Favero, E., Mucci, A., Galderisi, S., Gibertoni, D., Rossi, A., Rocca, P., Bertolino, A., Aguglia, E., Amore, M., Bellomo, A., Biondi, M., Blasi, G., Brasso, C., Bucci, P., Carpiniello, B., Cuomo, A., Dell'Osso, L., Giordano, G. M., Marchesi, C., Monteleone, P., Niolu, C., Oldani, L., Pettorruso, M., Pompili, M., Roncone, R., Rossi, R., Tenconi, E., Vita, A., Zeppegno, P., Maj, M., Mucci A., Galderisi S., Gibertoni D., Rossi A., Rocca P., Bertolino A., Aguglia E., Amore M., Bellomo A., Biondi M., Blasi G., Brasso C., Bucci P., Carpiniello B., Cuomo A., Dell'Osso L., Giordano G.M., Marchesi C., Monteleone P., Niolu C., Oldani L., Pettorruso M., Pompili M., Roncone R., Rossi R., Tenconi E., Vita A., Zeppegno P., and Maj M.

Subjects
Adult, Hospitals, Psychiatric, Male, Mental Health Services, Social Cognition, Apathy, Psychological intervention, Relapse prevention, schizophrenia, functioning, psychopatology, Structural equation modeling, 03 medical and health sciences, 0302 clinical medicine, Medicine, Humans, Cognitive Dysfunction, Female, Follow-Up Studies, Independent Living, Italy, Middle Aged, Psychotic Disorders, Schizophrenia, Functional Status, Original Investigation, business.industry, Mental health, Hospitals, Cognitive training, 030227 psychiatry, Psychiatry and Mental health, Settore MED/25, schizophrenia, real-life functioning, SEM, Psychiatric, Work Skills, business, Psychosocial, 030217 neurology & neurosurgery, Psychopathology, Clinical psychology
Abstract

Importance: The goal of schizophrenia treatment has shifted from symptom reduction and relapse prevention to functional recovery; however, recovery rates remain low. Prospective identification of variables associated with real-life functioning domains is essential for personalized and integrated treatment programs. Objective: To assess whether baseline illness-related variables, personal resources, and context-related factors are associated with work skills, interpersonal relationships, and everyday life skills at 4-year follow-up. Design, Setting, and Participants: This multicenter prospective cohort study was conducted across 24 Italian university psychiatric clinics or mental health departments in which 921 patients enrolled in a cross-sectional study were contacted after 4 years for reassessment. Recruitment of community-dwelling, clinically stable persons with schizophrenia was conducted from March 2016 to December 2017, and data were analyzed from January to May 2020. Main Outcomes and Measures: Psychopathology, social and nonsocial cognition, functional capacity, personal resources, and context-related factors were assessed, with real-life functioning as the main outcome. Structural equation modeling, multiple regression analyses, and latent change score modeling were used to identify variables that were associated with real-life functioning domains at follow-up and with changes from baseline in these domains. Results: In total, 618 participants (427 male [69.1%]; mean [SD] age, 45.1 [10.5] years) were included. Five baseline variables were directly associated with real-life functioning at follow-up: neurocognition with everyday life (β, 0.274; 95% CI, 0.207-0.341; P

Published
2021

4. Simple parameters from complete blood count predict in-hospital mortality in covid-19

Author

Bellan, M., Azzolina, D., Hayden, E., Gaidano, G., Pirisi, M., Acquaviva, A., Aimaretti, G., Valletti, P. A., Angilletta, R., Arioli, R., Avanzi, G. C., Avino, G., Balbo, P. E., Baldon, G., Baorda, F., Barbero, E., Baricich, A., Barini, M., Barone-Adesi, F., Battistini, S., Beltrame, M., Bertoli, M., Bertolin, S., Bertolotti, M., Betti, M., Bobbio, F., Boffano, P., Boglione, L., Borre, S., Brucoli, M., Calzaducca, E., Cammarata, E., Cantaluppi, V., Cantello, R., Capponi, A., Carriero, A., Casciaro, G. F., Castello, L. M., Ceruti, F., Chichino, G., Chirico, E., Cisari, C., Cittone, M. G., Colombo, C., Comi, C., Croce, E., Daffara, T., Danna, P., Corte, F. D., de Vecchi, S., Dianzani, U., Benedetto, D. D., Esposto, E., Faggiano, F., Falaschi, Z., Ferrante, D., Ferrero, A., Gagliardi, I., Galbiati, A., Gallo, S., Garavelli, P. L., Gardino, C. A., Garzaro, M., Gastaldello, M. L., Gavelli, F., Gennari, A., Giacomini, G. M., Giacone, I., Via, V. G., Giolitti, F., Gironi, L. C., Gramaglia, C., Grisafi, L., Inserra, I., Invernizzi, M., Krengli, M., Labella, E., Landi, I. C., Landi, R., Leone, I., Lio, V., Lorenzini, L., Maconi, A., Malerba, M., Manfredi, G. F., Martelli, M., Marzari, L., Marzullo, P., Mennuni, M., Montabone, C., Morosini, U., Mussa, M., Nerici, I., Nuzzo, A., Olivieri, C., Padelli, S. A., Panella, M., Parisini, A., Pasche, A., Patrucco, F., Patti, G., Pau, A., Pedrinelli, A. R., Percivale, I., Ragazzoni, L., Re, R., Rigamonti, C., Rizzi, E., Rognoni, A., Roveta, A., Salamina, L., Santagostino, M., Saraceno, M., Savoia, P., Sciarra, M., Schimmenti, A., Scotti, L., Spinoni, E., Smirne, C., Tarantino, V., Tillio, P. A., Tonello, S., Vaschetto, R., Vassia, V., Zagaria, D., Zavattaro, E., Zeppegno, P., Zottarelli, F., Sainaghi, P. P., Aiosa, G., Airoldi, A., Barco, A., Bargiacchi, O., Bazzano, S., Berni, P., Bianchi, B., Bianco, S., Biffi, S., Binda, V., Bolgeo, T., Bolla, C., Bonato, V., Bonizzoni, G., Bragantini, A., Brustia, D., Bullara, V., Burlone, M., Brustia, F., Caccia, S., Calareso, A., Cammarota, G., Cancelliere, L., Carbone, R., Cassinari, A., Ceriani, E., Cena, T., Clivati, E., Collimedaglia, L., Colombatto, A., Cornella, C., Costanzo, M., Croce, A., de Benedittis, C., Delorenzi, S., Dionisio, R., Donato, P., Esposito, M., Fangazio, S., Feggi, A., Ferrillo, S., Foci, V., Fra, G. P., Gaggino, C., Gambaro, E., Gattoni, E., Gattoni, L., Giacchero, F., Gianfreda, R., Giubertoni, A., Grecu, L., Grossi, F., Guglielmetti, G., Guido, S., Iannantuoni, G., Ingrao, S., Jona, A., Lazzarich, E., Lissandrin, R., Maduli, E., Magne, F., Mantia, E., Marangon, D., Massara, M., Matino, E., Mauri, M. G., Menegatti, M., Moglia, R., Molinari, R., Morelli, S., Morlino, P., Naldi, P., Nebbiolo, C., Omodeo, P., Palmieri, D., Panero, A., Parodi, M., Pedrazzoli, R., Pelazza, C., Penpa, S., Perucca, R., Pirovano, A., Pittau, S., Pochetti, P., Poletti, F., Polla, B., Prandi, P., Prodam, F., Prosperini, P., Puma, A., Quaglia, M., Raie, A., Rapetti, R., Ravera, S., Re, A., Reale, M., Rossati, A., Rossi, M., Rossi, P., Rostagno, R., Salomoni, G., Sama, M. T., Sarchi, E., Sarcoli, M., Sarda, C., Sguazzotti, I., Soddu, D., Sola, D., Stobbione, P., Todoerti, M., Vallese, G. C., Varrasi, C., Veia, A., Vignazia, G. L., Zanotti, I., Zecca, E., Zichittella, D., Zisa, G., and Zoppis, E.

Subjects
Adult, Male, medicine.medical_specialty, Medicine (General), Multivariate analysis, Article Subject, Clinical Decision Rules, COVID-19, Prognosis, Blood Cell Count, Hospital Mortality, Severity of Illness Index, Clinical Biochemistry, Asymptomatic, Severity of Illness Index, NO, R5-920, Internal medicine, Clinical Decision Rules, Severity of illness, Genetics, 80 and over, Medicine, Humans, Hospital Mortality, Molecular Biology, Aged, Retrospective Studies, Aged, 80 and over, medicine.diagnostic_test, business.industry, Biochemistry (medical), Complete blood count, COVID-19, Retrospective cohort study, Red blood cell distribution width, General Medicine, Odds ratio, Middle Aged, Prognosis, Female, Italy, Multivariate Analysis, Blood Cell Count, Cohort, medicine.symptom, business, Research Article
Abstract

Introduction. The clinical course of Coronavirus Disease 2019 (COVID-19) is highly heterogenous, ranging from asymptomatic to fatal forms. The identification of clinical and laboratory predictors of poor prognosis may assist clinicians in monitoring strategies and therapeutic decisions. Materials and Methods. In this study, we retrospectively assessed the prognostic value of a simple tool, the complete blood count, on a cohort of 664 patients ( F 260; 39%, median age 70 (56-81) years) hospitalized for COVID-19 in Northern Italy. We collected demographic data along with complete blood cell count; moreover, the outcome of the hospital in-stay was recorded. Results. At data cut-off, 221/664 patients (33.3%) had died and 453/664 (66.7%) had been discharged. Red cell distribution width (RDW) ( χ 2 10.4; p < 0.001 ), neutrophil-to-lymphocyte (NL) ratio ( χ 2 7.6; p = 0.006 ), and platelet count ( χ 2 5.39; p = 0.02 ), along with age ( χ 2 87.6; p < 0.001 ) and gender ( χ 2 17.3; p < 0.001 ), accurately predicted in-hospital mortality. Hemoglobin levels were not associated with mortality. We also identified the best cut-off for mortality prediction: a NL ratio > 4.68 was characterized by an odds ratio for in-hospital mortality OR = 3.40 (2.40-4.82), while the OR for a RDW > 13.7 % was 4.09 (2.87-5.83); a platelet count > 166,000 /μL was, conversely, protective (OR: 0.45 (0.32-0.63)). Conclusion. Our findings arise the opportunity of stratifying COVID-19 severity according to simple lab parameters, which may drive clinical decisions about monitoring and treatment.

Published
2021

5. Clara Sereni. Sconfinamenti e ritorni

Author

Barenghi, M, Garbo, R, Manghetti, G, Centovalli, B, Gambaro, E, Testa, E, Scriccioli, PV, Caputo, F, Farina, F, Silvestri, F, Francesca Caputo, Barenghi, M, Garbo, R, Manghetti, G, Centovalli, B, Gambaro, E, Testa, E, Scriccioli, PV, Caputo, F, Farina, F, Silvestri, F, and Francesca Caputo

Abstract

L'intervento prende in esame l'organizzazione testuale per lasse, tessere dei libri dell'autrice, variamente disposte a costruire comunque un insieme coerente e il ritorno di libro in libro di figure, oggetti, temi e linguaggi.

Published
2021

6. The association between insight and depressive symptoms in schizophrenia: Undirected and Bayesian network analyses

Author

Amore, M., Murri, M. B., Calcagno, P., Rocca, P., Rossi, A., Aguglia, E., Bellomo, A., Blasi, G., Carpiniello, B., Cuomo, A., Dell'Osso, L., Di Giannantonio, M., Giordano, G. M., Marchesi, C., Monteleone, P., Montemagni, C., Oldani, L., Pompili, M., Roncone, R., Rossi, R., Siracusano, A., Vita, A., Zeppegno, P., Corso, A., Arzani, C., Galderisi, S., Maj, M., Petrilli, G., Respino, M., Papalino, M., Falsetti, A., Calia, V. M., Barlati, S., Deste, G., Turrina, C., Pinna, F., Lai, A., Di Santa Sofia, S. L., Signorelli, M. S., Petralia, A., Pettorruso, M., Barone, G., Salone, A., Piegari, G., Aiello, C., Brando, F., Giuliani, L., Altamura, M., Carnevale, R., Padalino, F., Giusti, L., Salza, A., Ussorio, D., Pizziconi, G., Santarelli, V., Pacitti, F., De Bartolomeis, A., Gambaro, E., Gattoni, E., Gramaglia, C., De Panfilis, C., Ossola, P., Tonna, M., Carmassi, C., Carpita, B., Cremone, I., Comparelli, A., Corigliano, V., Brugnoli, R., Corrivetti, G., Cascino, G., Del Buono, G., Fagiolini, A., Bolognesi, S., Goracci, A., Di Lorenzo, G., Niolu, C., Ribolsi, M., Bellino, S., Bozzatello, P., Brasso, C., Amore, M., Murri, M. B., Calcagno, P., Rocca, P., Rossi, A., Aguglia, E., Bellomo, A., Blasi, G., Carpiniello, B., Cuomo, A., Dell'Osso, L., di Giannantonio, M., Giordano, G. M., Marchesi, C., Monteleone, P., Montemagni, C., Oldani, L., Pompili, M., Roncone, R., Rossi, R., Siracusano, A., Vita, A., Zeppegno, P., Corso, A., Arzani, C., Galderisi, S., and Maj, M.

Subjects
Adult, Male, media_common.quotation_subject, Social Stigma, Hostility, NO, Suicidal Ideation, Extrapyramidal symptoms, Demoralization, depression, insight, sadness, schizophrenia, self-esteem, Sadness, Self-esteem, medicine, Humans, Suicidal ideation, media_common, Depression, Insight, Schizophrenia, Bayes Theorem, Cross-Sectional Studies, Diagnostic and Statistical Manual of Mental Disorders, Female, Middle Aged, Self Concept, Social Class, Guilt, Schizophrenic Psychology, Positive and Negative Syndrome Scale, Sadne, medicine.disease, Psychiatry and Mental health, Settore MED/25, medicine.symptom, Psychology, Neurocognitive, Research Article, Clinical psychology, Diagnosis of schizophrenia
Abstract

Background. Greater levels of insight may be linked with depressive symptoms among patients with schizophrenia, however, it would be useful to characterize this association at symptom-level, in order to inform research on interventions. Methods. Data on depressive symptoms (Calgary Depression Scale for Schizophrenia) and insight (G12 item from the Positive and Negative Syndrome Scale) were obtained from 921 community-dwelling, clinically-stable individuals with a DSM-IV diagnosis of schizophrenia, recruited in a nationwide multicenter study. Network analysis was used to explore the most relevant connections between insight and depressive symptoms, including potential confounders in the model (neurocognitive and social-cognitive functioning, positive, negative and disorganization symptoms, extrapyramidal symptoms, hostility, internalized stigma, and perceived discrimination). Bayesian network analysis was used to estimate a directed acyclic graph (DAG) while investigating the most likely direction of the putative causal association between insight and depression. Results. After adjusting for confounders, better levels of insight were associated with greater self-depreciation, pathological guilt, morning depression and suicidal ideation. No difference in global network structure was detected for socioeconomic status, service engagement or illness severity. The DAG confirmed the presence of an association between greater insight and self-depreciation, suggesting the more probable causal direction was from insight to depressive symptoms. Conclusions. In schizophrenia, better levels of insight may cause self-depreciation and, possibly, other depressive symptoms. Person-centered and narrative psychotherapeutic approaches may be particularly fit to improve patient insight without dampening self-esteem., Highlights Better insight seems associated with depressive symptoms in schizophrenia.Network analyses were used to explore this association in a large sample.Insight was associated with self-depreciation, guilt, and suicidal ideation.Although cross-sectional, data suggest causal direction from insight to depression.

Published
2020

7. The complex relationship between self-reported 'personal recovery' and clinical recovery in schizophrenia

Author

Rossi, A, Amore, M, Galderisi, S, Rocca, P, Bertolino, A, Aguglia, E, Amodeo, G, Bellomo, A, Bucci, P, Buzzanca, A, Carpiniello, B, Comparelli, A, Dell'Osso, L, Giannantonio, M, Mancini, M, Marchesi, C, Monteleone, P, Montemagni, C, Oldani, L, Roncone, R, Siracusano, A, Stratta, P, Tenconi, E, Vignapiano, A, Vita, A, Zeppegno, P, Maj, M, Rossetti, M, Rossi, R, Santarelli, V, Giusti, L, Malavolta, M, Salza, A, Palumbo, D, Patriarca, S, Chieffi, M, Attrotto, M, Colagiorgio, L, Andriola, I, Atti, A, Barlati, S, Deste, G, Galluzzo, A, Pinna, F, Deriu, L., Sanna, L, Signorelli, M., Minutolo, G, Cannavò, D, Martinotti, G, Acciavatti, T, Corbo, M, Altamura, M, Carnevale, R, Malerba, S, Murri, M, Calcagno, P, Bugliani, M, Serati, M, Bartolomeis, A, Gramaglia, C, Gattoni, E, Gambaro, E, Collantoni, E, Cremonese, C, Rossi, E, Ossola, P, Tonna, M, Panfilis, C, Rutigliano, G, Gesi, C, Carmassi, C, Biondi, M, Girardi, P, Brugnoli, R, Fabio, F, Pietro, S, Girardi, N, Niolu, C, Lorenzo, G, Ribolsi, M, Corrivetti, G, Pinto, G, Longobardi, N, Fagiolini, A, Goracci, A, Bolognesi, S, Bellino, S, Villari, V, Bracale, N, Rossi, A., Amore, M., Galderisi, S., Rocca, P., Bertolino, A., Aguglia, E., Amodeo, G., Bellomo, A., Bucci, P., Buzzanca, A., Carpiniello, B., Comparelli, A., Dell'Osso, L., Giannantonio, M. D., Mancini, M., Marchesi, C., Monteleone, P., Montemagni, C., Oldani, L., Roncone, R., Siracusano, A., Stratta, P., Tenconi, E., Vignapiano, A., Vita, A., Zeppegno, P., Maj, M., Rossetti, M. C., Rossi, R., Santarelli, V., Giusti, L., Malavolta, M., Salza, A., Palumbo, D., Patriarca, S., Chieffi, M., Attrotto, M. T., Colagiorgio, L., Andriola, I., Atti, A. R., Barlati, S., Deste, G., Galluzzo, A., Pinna, F., Deriu, L., Sanna, L., Signorelli, M. S., Minutolo, G., Cannavo, D., Martinotti, G., Acciavatti, T., Corbo, M., Altamura, M., Carnevale, R., Malerba, S., Murri, M. B., Calcagno, P., Bugliani, M., Serati, M., Bartolomeis, A., Gramaglia, C., Gattoni, E., Gambaro, E., Collantoni, E., Cremonese, C., Rossi, E., Ossola, P., Tonna, M., Panfilis, C. D., Rutigliano, G., Gesi, C., Carmassi, C., Biondi, M., Girardi, P., Brugnoli, R., Fabio, F. D., Pietro, S. D., Girardi, N., Niolu, C., Lorenzo, G. D., Ribolsi, M., Corrivetti, G., Pinto, G., Longobardi, N., Fagiolini, A., Goracci, A., Bolognesi, S., Bellino, S., Villari, V., and Bracale, N.

Subjects
Adult, Male, Schizophrenia, Personal recovery, Clinical recovery, Insight, Recovery styles, Cluster analysis, Clinical recovery, Coping (psychology), Cross-sectional study, Recovery style, 03 medical and health sciences, Diagnostic Self Evaluation, 0302 clinical medicine, Cluster analysis, Recovery styles, Insight, Personal recovery, Schizophrenia, Cluster Analysis, Cross-Sectional Studies, Female, Humans, Psychiatric Status Rating Scales, Self Report, Recovery of Function, Schizophrenic Psychology, Cluster analysi, Self report, Settore MED/25 - Psichiatria, Biological Psychiatry, 030227 psychiatry, Psychiatry and Mental Health, Psychiatric status rating scales, Biological psychiatry, Psychology, 030217 neurology & neurosurgery, Clinical psychology
Abstract

Self-reported 'personal recovery' and clinical recovery in schizophrenia (SRPR and CR. respectively) reflect different perspectives in schizophrenia outcome, not necessarily concordant with each other and usually representing the consumer's or the therapist's point of view. By means of a cluster analysis on SRPR related variables, we identified three dusters. The first and third cluster included subjects with the best and the poorest clinical outcome respectively. The second cluster was characterized by better insight, higher levels of depression and stigma, lowest self-esteem and personal strength, and highest emotional coping. The first duster showed positive features of recovery, while the third duster showed negative features. The second cluster, with the most positive insight, showed a more complex pattern, a some-what 'paradoxical' mixture of positive and negative personal and clinical features of recovery. The present results suggest the need for a characterization of persons with schizophrenia along SRPR and CR dimensions to design individualized and integrated treatment programs aimed to improve insight and coping strategies, reduce stigma and shape recovery styles. (C) 2017 Elsevier B.V. All rights reserved.

Published
2018

8. Massini liturgico e aneddotico

Author

Turchetta, G, Gambaro, E, Rosa, G, Cenati, G, Novelli, M, Sergio, G, Petruzzi, MS, Barenghi, M, Ghidinelli, S, Gallarini, L, Raccis, G, Daino, L, Fiori, U, Porcelli, T, Caputo, F, Sullam, S, Strazzeri, G, Galbiati, W, Dubini, P, Pallotta, V, Falcetto, B, Cosat, P, Terreni, A, Cesana, R, Parise, S, Spinazzola, V, Turchetta, G, Gambaro, E, Rosa, G, Cenati, G, Novelli, M, Sergio, G, Petruzzi, MS, Barenghi, M, Ghidinelli, S, Gallarini, L, Raccis, G, Daino, L, Fiori, U, Porcelli, T, Caputo, F, Sullam, S, Strazzeri, G, Galbiati, W, Dubini, P, Pallotta, V, Falcetto, B, Cosat, P, Terreni, A, Cesana, R, Parise, S, and Spinazzola, V

Abstract

Drammaturgo, narratore, affabulatore, Massini affronta temi grandi e piccoli della realtà contemporanea ritagliando storie e teatralizzandole: sia nella lunga saga della famiglia Lehman, sia negli episodi esemplari raccontati in pochi minuti, lo strumento decisivo è sempre la modulazione recitante della voce.

Published
2019

13. Delle Società costituite all'estero. Artt. 2507-2510

Author

BISCARETTI DI RUFFIA, CLAUDIO, Gambaro, E., BISCARETTI DI RUFFIA, C, and Gambaro, E

Subjects
trattamento, IUS/14 - DIRITTO DELL'UNIONE EUROPEA, sede secondaria, IUS/13 - DIRITTO INTERNAZIONALE, diritto comunitario, società estere
Published
2013

14. L’autoritratto di una generazione

Author

Turchetta, G, Pischedda, B, Spianzzola, V, Cosa, P, Novelli, M, Cenati, G, Sergio, G, Falcetto, B, Porcelli, T, Speciale, A, Rosa, G, Gallarini, L, Gambaro E, Interdonato, P, Palieri, MS, Barenghi, M, Giovannetti, P, Fiori, U, Dubini, P, Galbiati, W, Zapparoli, M, Moretti, D, Maccarelli, L, Attanasio, P, Pallotta, W, Bona, F, Daino, L, Petruzzi, MS, Terreni, A, Mussinelli, C, Sullam, S, Cesana, R, Parise, F, Spinazzola, V, BARENGHI, MARIO LUIGI, Turchetta, G, Pischedda, B, Spianzzola, V, Cosa, P, Novelli, M, Cenati, G, Sergio, G, Falcetto, B, Porcelli, T, Speciale, A, Rosa, G, Gallarini, L, Gambaro E, Interdonato, P, Palieri, MS, Barenghi, M, Giovannetti, P, Fiori, U, Dubini, P, Galbiati, W, Zapparoli, M, Moretti, D, Maccarelli, L, Attanasio, P, Pallotta, W, Bona, F, Daino, L, Petruzzi, MS, Terreni, A, Mussinelli, C, Sullam, S, Cesana, R, Parise, F, Spinazzola, V, and BARENGHI, MARIO LUIGI

Abstract

Né vera e propria narrazione romanzesca, né autofiction, "La scuola cattolica" di Edoardo Albinati costituisce per molti aspetti il libro di un'intera generazione; ma questo non solo per le accurate ricostruzioni storico-sociali e per il tentativo di ritrarre il processo di formazione di un'intera mentalità. È infatti soprattutto nella sua prolissità e dispersione che il testo sembra rispecchiare le difficoltà degli ex baby-boomers nel trasmettere ai propri figli il senso e l'eredità di una esperienza.

Published
2017

15. Anger Expression, Impulsivity And Expressed Emotion: a Comparison Between Patients With Eating Disorder And Schizophrenia

Author

Gambaro, E., primary, Gramaglia, C., additional, Cenci, D., additional, Delicato, C., additional, Lombardi, A., additional, Rizza, C., additional, Girardi, L., additional, Binda, V., additional, Chieppa, N., additional, Prosperini, P., additional, Bert, F., additional, Siliquini, R., additional, and Zeppegno, P., additional

Published
2016
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21. Early Rehabilitation in a Psychiatric Ward for Acute Patients: the Experience of the S.C. Psichiatria, Aou Maggiore Della Carità, Novara, Italy

Author

Di Marco, S., primary, Zeppegno, P., additional, Feggi, A., additional, Lombardi, A., additional, Rossi, A., additional, Gattoni, E., additional, Gambaro, E., additional, Delicato, C., additional, Antona, M., additional, Rizza, M.C., additional, Coppola, I., additional, Bergamasco, P., additional, Gramaglia, C., additional, and Torre, E., additional

Published
2015
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24. Anxiety and Expressed Emotion in a Sample of Obese Patients

Author

Gattoni, E., primary, Gramaglia, C., additional, Biroli, G., additional, D'Andrea, F., additional, Coppola, I., additional, Rizza, M.C., additional, Gambaro, E., additional, Lombardi, A., additional, Gili, S., additional, Di Tullio, E., additional, and Zeppegno, P., additional

Published
2015
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25. Feeling Through the Body: Alexithymia and Eating Disorders

Author

Lombardi, A., primary, Gambaro, E., additional, Prosperini, P., additional, Antona, M., additional, Delicato, C., additional, Feggi, A., additional, Rizza, M.C., additional, Palazzolo, A., additional, Binda, V., additional, Chieppa, N., additional, Do, F., additional, Gramaglia, C., additional, and Zeppegno, P., additional

Published
2015
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26. Unlawful State Aid : Protection by National Courts

Author

Santa Maria, A., Biscaretti di Ruffia, C., Gambaro, E., Reni, M., Papi Rossi, A., Landi, N., Piroddi, P., and Tedoldi, A.

Subjects
Unlawful State Aid Protection by National Courts, Settore IUS/15 - Diritto Processuale Civile
Published
2007

27. Gli adorati arricchiti di Edoardo Nesi

Author

Spinazzola, V, Rosa, G, Giovannetti, P, Clerici, L, Pischedda, B, Cenati, G, Cerutti, L, Gambaro, E, Rollo, A, Ghidinelli, S, Turchetta, G, Barenghi. M, Daino, L, Carnero, R, Interdonato, P, Petruzzi, MS, Bona, F, Coyaud, S, Fiori, U, Dubini, P, Palieri, MS, Cesana, R, de Rosa, D, Lepri, L, Novelli, M, Cadili, A, Barbisan, I, Gambaro, M, Attanasio, P, Salis, S, Moretti, D, Terreni, A, Massinelli, C, Parise, S, Sullam, S, Cardone, R, Spimazzola, V., Barenghi, M, BARENGHI, MARIO LUIGI, Spinazzola, V, Rosa, G, Giovannetti, P, Clerici, L, Pischedda, B, Cenati, G, Cerutti, L, Gambaro, E, Rollo, A, Ghidinelli, S, Turchetta, G, Barenghi. M, Daino, L, Carnero, R, Interdonato, P, Petruzzi, MS, Bona, F, Coyaud, S, Fiori, U, Dubini, P, Palieri, MS, Cesana, R, de Rosa, D, Lepri, L, Novelli, M, Cadili, A, Barbisan, I, Gambaro, M, Attanasio, P, Salis, S, Moretti, D, Terreni, A, Massinelli, C, Parise, S, Sullam, S, Cardone, R, Spimazzola, V., Barenghi, M, and BARENGHI, MARIO LUIGI

Abstract

La parabola di Edoardo Nesi, scrittore che a lungo si è diviso tra il mondo delle lettere e quello imprenditoriale, è un caso pressoché unico nel panorama letterario nazionale: la sua "doppia vita" gli ha però permesso di raccontare dall'interno, in romanzi che sono tutti variazioni su un unico tema, l'ascesa e la caduta di un distretto industriale.

Published
2013

28. Penetrating esophageal injuries: multicenter study of the American Association for the Surgery of Trauma

Author

Frank B. Miller, Orlando C. Kirton, Michael C. Stoner, Lake J, Erwin F. Hirsch, Emily Ramicone, Kralovich K, Jorge I. Cué, Mark A. Malangoni, Schmacht D, William F. Fallon, Walter Forno, Dunham Cm, Falcone R, Dennis Wang, Gayle Minard, Juan A. Asensio, Marc J. Shapiro, Erin C. Dunn, Wall M, Rao R. Ivatury, Robert J. Winchell, Santiago Chahwan, Ronald J. Simon, Richard M. Bell, Robert Coscia, Chang B, Ralph L. Warren, Susan I. Brundage, Gambaro E, David Hanpeter, McGuire E, Fred A. Luchette, Ceballos J, David J. Dries, David B. Hoyt, Jay A. Yelon, Linda S. Chan, Kathy Alo, Leonard J. Weireter, Robert C. Mackersie, Melissa A. Powell, Rodriquez J, Rue L rd, Riyad Karmy-Jones, C. W. Schwab, Anna M. Ledgerwood, Kimball I. Maull, Blaine L. Enderson, Heidi L. Frankel, L. D. Britt, Michael West, Torcal J, Kimberly Nagy, and John P. Sherck

Subjects
Adult, Male, medicine.medical_specialty, Adolescent, Wounds, Penetrating, Wounds, Stab, Neck Injuries, Esophagus, Risk Factors, Epidemiology, medicine, Humans, Risk factor, Child, Aged, Retrospective Studies, Aged, 80 and over, Esophageal disease, business.industry, Retrospective cohort study, Length of Stay, Middle Aged, medicine.disease, Surgery, medicine.anatomical_structure, Upper aerodigestive tract, Logistic Models, Multicenter study, Child, Preschool, Female, Wounds, Gunshot, business, Complication
Abstract

The purpose of this study was to define the period of time after which delays in management incurred by investigations cause increased morbidity and mortality. The outcome study is intended to correlate time with death from esophageal causes, overall complications, esophageal related complications, and surgical intensive care unit length of stay.This was a retrospective multicenter study involving 34 trauma centers in the United States, under the auspices of the American Association for the Surgery of Trauma Multi-institutional Trials Committee over a span of 10.5 years. Patients surviving to reach the operating room (OR) were divided into two groups: those that underwent diagnostic studies to identify their injuries (preoperative evaluation group) and those that went immediately to the OR (no preoperative evaluation group). Statistical methods included Fisher's exact test, Student's T test, and logistic regression analysis.The study involved 405 patients: 355 male patients (86.5%) and 50 female patients (13.5%). The mean Revised Trauma Score was 6.3, the mean Injury Severity Score was 28, and the mean time interval to the OR was 6.5 hours. There were associated injuries in 356 patients (88%), and an overall complication rate of 53.5%. Overall mortality was 78 of 405 (19%). Three hundred forty-six patients survived to reach the OR: 171 in the preoperative evaluation group and 175 in the no preoperative evaluation group. No statistically significant differences were noted in the two groups in the following parameters: number of patients, age, Injury Severity Score, admission blood pressure, anatomic location of injury (cervical or thoracic), surgical management (primary repair, resection and anastomosis, resection and diversion, flaps), number of associated injuries, and mortality. Average length of time to the OR was 13 hours in the preoperative evaluation group versus 1 hour in the no preoperative evaluation group (p0.001). Overall complications occurred in 134 in the preoperative evaluation group versus 87 in the no preoperative evaluation group (p0.001), and 74 (41%) esophageal related complications occurred in the preoperative evaluation group versus 32 (19%) in the no preoperative evaluation group (p = 0.003). Mean surgical intensive care unit length of stay was 11 days in the preoperative evaluation group versus 7 days in the no preoperative evaluation group (p = 0.012). Logistic regression analysis identified as independent risk factors for the development of esophageal related complications included time delays in preoperative evaluation (odds ratio, 3.13), American Association for the Surgery of Trauma Organ Injury Scale grade2 (odds ratio, 2.62), and resection and diversion (odds ratio, 4.47).Esophageal injuries carry a high morbidity and mortality. Increased esophageal related morbidity occurs with the diagnostic workup and its inherent delay in operative repair of these injuries. For centers practicing selective management of penetrating neck injuries and transmediastinal gunshot wounds, rapid diagnosis and definitive repair should be made a high priority.

Published
2001

32. Baricco e la nostalgia della modernità

Author

Pischedda, B, Novelli, M, Turchetta, G, Cenati, G, Bona, F, Marigonda, E, Giovannetti, P, Nani, G, Spinazzola, V, Strazzeri, G, Barenghi, M, Rosa, G, Richelmi, C, Gambaro, E, Fiori, U, Coyaud, S, Petruzzi, MS, Moretti, D, Minoia, C, Palieri, MS, Gambaro, F, Carnero, R, Terreni, A, Clerici, L, Cadioli, A, Ghidinelli, S, Dubini, P, Maiello, R, Moscati, G, Attanasio, P, Gallo, G, Massinelli, C, Cardone, R, BARENGHI, MARIO LUIGI, Pischedda, B, Novelli, M, Turchetta, G, Cenati, G, Bona, F, Marigonda, E, Giovannetti, P, Nani, G, Spinazzola, V, Strazzeri, G, Barenghi, M, Rosa, G, Richelmi, C, Gambaro, E, Fiori, U, Coyaud, S, Petruzzi, MS, Moretti, D, Minoia, C, Palieri, MS, Gambaro, F, Carnero, R, Terreni, A, Clerici, L, Cadioli, A, Ghidinelli, S, Dubini, P, Maiello, R, Moscati, G, Attanasio, P, Gallo, G, Massinelli, C, Cardone, R, and BARENGHI, MARIO LUIGI

Abstract

Bilancio sull'opera di Alessandro Baricco. Spesso accusato di essere un autore di maniera, incline a compiacere le ambizioni estetiche di un pubblico dalle pretese non eccelse, Baricco ha una sorgente di ispirazione autentica. Sotto la sua scrittura patinata c'è Leitmotiv del rimpianto: un sentimento nostalgico dell'avvento della modernità, retrospettivo e introspettivo, incline alle sfumature patetiche, anche se reso con una narrazione dal ritmo incalzante, brioso, talvolta indiavolato. Le fissazioni melodrammatiche dei personaggi più riusciti svelano il loro ruolo di sognatori di utopie.E restituiscono il piacere affabulatorio di uno scrittore profondamente, inguaribilmente "letterario".

Published
2007

35. Bacteriology in infected abortion

Author

Farinati, A., primary, Soler, C.O., additional, Pagniez, G., additional, Gliosca, L., additional, Casellas, J., additional, Guntin, R., additional, Gambaro, E., additional, Soutric, J., additional, Arenoso, H., additional, and Caruso, N., additional

Published
2000
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36. Long acting injections (lais) 18 months follow-up naturalistic study in a north western italian public mental health service.

Author

Gambaro, E., Probo, M., Bossi, P., Feri, C., Dalò, V., and Gramaglia, C. M.

Subjects
*MENTAL health services, *PUBLIC health, *PATIENT compliance, *FOLLOW-up studies (Medicine), *MENTAL health
Abstract

Introduction: Many patients (pts) with schizophrenia exhibit difficulties in maintaining adherence to oral antipsychotics (OA). Long-acting injectable antipsychotics (LAI) may have a slight edge about promoting treatment adherence, reducing costs and rehospitalization rates. Objectives: To value demographic and clinical features, global functioning in schizophrenic using Haldol LAI (H-LAI) or second-generation antipsychotics (S-LAI). Methods: Follow up study (T0 January 2017; T1 18 months later) in naturalistic setting (Mental Health Service-MHS, Novara, Italy). Statistical analysis was performed with SPSS 19 and significance at p=0.05. Results: 90 pts were recruited (45 on H-LAI, 45 on S-LAI). At T1 4.4% pts on H-LAI modified therapy for inefficacy, 4.4 % switched to OA. At T1 Clinical Global Impression (CGI) and Personal and Social Performance (PSP) mean scores remained the same (respectively 85% and 83.8%). At T1 13 pts on SG LAI modified therapy (6 switching to other SG LAI, 4 to H-LAI and 3 to OA. CGI and PSP mean scores improved at T1 (respectively 27.6% and 43.8%). In terms of substance use and somatic comorbidity no statistical differences were found among the 2 groups at TO, neither in oral augmentation, anticholinergic use, hospitalization rate, CGI score between T0 and T1. S-LAI group was younger (p=.0009), reaching higher scores in PSP "care of self" (p=0.047) at T0 and was observed scores improvement of PSP "work" (p=0.049) and PSP total (p<0.001) at T1. Conclusions: the use of LAI among pts attending the MHS Novara, Italy, especially for S-LAI, increased among younger people with better functioning. [ABSTRACT FROM AUTHOR]

Published
2020

42. Accuracy of self-assessment of real-life functioning in schizophrenia

Author

Rocca, Paola, Brasso, Claudio, Montemagni, Cristiana, Bellino, Silvio, Rossi, Alessandro, Bertolino, Alessandro, Gibertoni, Dino, Aguglia, Eugenio, Amore, Mario, Andriola, Ileana, Bellomo, Antonello, Bucci, Paola, Buzzanca, Antonino, Carpiniello, Bernardo, Cuomo, Alessandro, Dell'Osso, Liliana, Favaro, Angela, Giordano, Giulia Maria, Marchesi, Carlo, Monteleone, Palmiero, Oldani, Lucio, Pompili, Maurizio, Roncone, Rita, Rossi, Rodolfo, Siracusano, Alberto, Vita, Antonio, Zeppegno, Patrizia, Galderisi, Silvana, Maj, Mario, Bozzatello, Paola, Badino, Cristina, Giordano, Benedetta, Di Palo, Piergiuseppe, Calia, Vitalba, Papalino, Marco, Barlati, Stefano, Deste, Giacomo, Ceraso, Anna, Pinna, Federica, Olivieri, Benedetta, Manca, Daniela, Piegari, Giuseppe, Brando, Francesco, Giuliani, Luigi, Aiello, Carmen, Fusar Poli, Laura, Concerto, Carmen, Surace, Teresa, Altamura, Mario, Malerba, Stefania, Padalino, Flavia, Calcagno, Pietro, Belvederi Murri, Martino, Amerio, Andrea, Pacitti, Francesca, Socci, Valentina, Lucaselli, Alessia, Giusti, Laura, Salza, Anna, Ussorio, Donatella, Iasevoli, Felice, Gramaglia, Carla, Gambaro, Eleonora, Gattoni, Eleonora, Tenconi, Elena, Collantoni, Enrico, Meneguzzo, Paolo, Ossola, Paolo, Tonna, Matteo, Gerra, Maria Lidia, Carmassi, Claudia, Carpita, Barbara, Cremone, Ivan Mirko, Corrivetti, Giulio, Cascino, Giammarco, Marciello, Francesca, Brugnoli, Roberto, Comparelli, Anna, Corigliano, Valentina, Girardi, Nicoletta, Accinni, Tommaso, Carlone, Luca, Fagiolini, Andrea, Goracci, Arianna, Bolognesi, Simone, Di Lorenzo, Giorgio, Niolu, Cinzia, Ribolsi, Michele, Rocca, P., Brasso, C., Montemagni, C., Bellino, S., Rossi, A., Bertolino, A., Gibertoni, D., Aguglia, E., Amore, M., Andriola, I., Bellomo, A., Bucci, P., Buzzanca, A., Carpiniello, B., Cuomo, A., Dell'Osso, L., Favaro, A., Giordano, G. M., Marchesi, C., Monteleone, P., Oldani, L., Pompili, M., Roncone, R., Rossi, R., Siracusano, A., Vita, A., Zeppegno, P., Galderisi, S., Maj, M., Bozzatello, P., Badino, C., Giordano, B., Di Palo, P., Calia, V., Papalino, M., Barlati, S., Deste, G., Ceraso, A., Pinna, F., Olivieri, B., Manca, D., Piegari, G., Brando, F., Giuliani, L., Aiello, C., Poli, L. F., Concerto, C., Surace, T., Altamura, M., Malerba, S., Padalino, F., Calcagno, P., Murri, M. B., Amerio, A., Pacitti, F., Socci, V., Lucaselli, A., Giusti, L., Salza, A., Ussorio, D., Iasevoli, F., Gramaglia, C., Gambaro, E., Gattoni, E., Tenconi, E., Collantoni, E., Meneguzzo, P., Ossola, P., Tonna, M., Gerra, M. L., Carmassi, C., Carpita, B., Cremone, I. M., Corrivetti, G., Cascino, G., Marciello, F., Brugnoli, R., Comparelli, A., Corigliano, V., Girardi, N., Accinni, T., Carlone, L., Fagiolini, A., Goracci, A., Bolognesi, S., Di Lorenzo, G., Niolu, C., Ribolsi, M., Rocca P., Brasso C., Montemagni C., Bellino S., Rossi A., Bertolino A., Gibertoni D., Aguglia E., Amore M., Andriola I., Bellomo A., Bucci P., Buzzanca A., Carpiniello B., Cuomo A., Dell'Osso L., Favaro A., Giordano G.M., Marchesi C., Monteleone P., Oldani L., Pompili M., Roncone R., Rossi R., Siracusano A., Vita A., Zeppegno P., Galderisi S., Maj M., Bozzatello P., Badino C., Giordano B., Di Palo P., Calia V., Papalino M., Barlati S., Deste G., Ceraso A., Pinna F., Olivieri B., Manca D., Piegari G., Brando F., Giuliani L., Aiello C., Poli L.F., Concerto C., Surace T., Altamura M., Malerba S., Padalino F., Calcagno P., Murri M.B., Amerio A., Pacitti F., Socci V., Lucaselli A., Giusti L., Salza A., Ussorio D., Iasevoli F., Gramaglia C., Gambaro E., Gattoni E., Tenconi E., Collantoni E., Meneguzzo P., Ossola P., Tonna M., Gerra M.L., Carmassi C., Carpita B., Cremone I.M., Corrivetti G., Cascino G., Marciello F., Brugnoli R., Comparelli A., Corigliano V., Girardi N., Accinni T., Carlone L., Fagiolini A., Goracci A., Bolognesi S., Di Lorenzo G., Niolu C., and Ribolsi M.

Subjects
Self-assessment, medicine.medical_treatment, Concordance, RC435-571, schizophrenia, real-life functioning, reliability, Article, Correlation, 03 medical and health sciences, Interpersonal relationship, 0302 clinical medicine, medicine, 030212 general & internal medicine, Self-assessment, schizophrenia, diagnosis, Psychiatry, Rehabilitation, medicine.disease, Psychosis, 030227 psychiatry, Psychiatry and Mental health, Settore MED/25, Schizophrenia, Cohort, Work Skills, Psychology, Clinical psychology
Abstract

A consensus has not yet been reached regarding the accuracy of people with schizophrenia in self-reporting their real-life functioning. In a large (n = 618) cohort of stable, community-dwelling schizophrenia patients we sought to: (1) examine the concordance of patients’ reports of their real-life functioning with the reports of their key caregiver; (2) identify which patient characteristics are associated to the differences between patients and informants. Patient-caregiver concordance of the ratings in three Specific Level of Functioning Scale (SLOF) domains (interpersonal relationships, everyday life skills, work skills) was evaluated with matched-pair t tests, the Lin’s concordance correlation, Somers’ D, and Bland–Altman plots with limits of agreement (LOA). Predictors of the patient-caregiver differences in SLOF ratings were assessed with a linear regression with multivariable fractional polynomials. Patients’ self-evaluation of functioning was higher than caregivers’ in all the evaluated domains of the SLOF and 17.6% of the patients exceeded the LOA, thus providing a self-evaluation discordant from their key caregivers. The strongest predictors of patient-caregiver discrepancies were caregivers’ ratings in each SLOF domain. In clinically stable outpatients with a moderate degree of functional impairment, self-evaluation with the SLOF scale can become a useful, informative and reliable clinical tool to design a tailored rehabilitation program.

Published
2021

44. The interplay among psychopathology, personal resources, context-related factors and real-life functioning in schizophrenia: stability in relationships after 4 years and differences in network structure between recovered and non-recovered patients

Author

Galderisi, Silvana, Rucci, Paola, Mucci, Armida, Rossi, Alessandro, Rocca, Paola, Bertolino, Alessandro, Aguglia, Eugenio, Amore, Mario, Bellomo, Antonello, Bozzatello, Paola, Bucci, Paola, Carpiniello, Bernardo, Collantoni, Enrico, Cuomo, Alessandro, Dell'Osso, Liliana, Di Fabio, Fabio, di Giannantonio, Massimo, Gibertoni, Dino, Giordano, Giulia Maria, Marchesi, Carlo, Monteleone, Palmiero, Oldani, Lucio, Pompili, Maurizio, Roncone, Rita, Rossi, Rodolfo, Siracusano, Alberto, Vita, Antonio, Zeppegno, Patrizia, Maj, Mario, Italian Network for Research on Psychoses, Francesco, Catapano, Giuseppe, Piegari, Carmen, Aiello, Francesco, Brando, Luigi, Giuliani, Daria, Pietrafesa, Marco, Papalino, Giovanni, Mercadante, Piergiuseppe, Di Palo, Stefano, Barlati, Giacomo, Deste, Paolo, Valsecchi, Federica, Pinna, Benedetta, Olivieri, Daniela, Manca, Maria Salvina, Signorelli, Laura, Fusar Poli, Domenico, De Berardis, Silvia, Fraticelli, Mariangela, Corbo, Stefano, Pallanti, Mario, Altamura, Raffaella, Carnevale, Stefania, Malerba, Pietro, Calcagno, Domenico, Zampogna, Alessandro, Corso, Giusti, Laura, Salza, Anna, Ussorio, Donatella, Talevi, Dalila, Socci, Valentina, Pacitti, Francesca, Andrea, de Bartolomeis, Carla, Gramaglia, Eleonora, Gambaro, Eleonora, Gattoni, Angela, Favaro, Elena, Tenconi, Paolo, Meneguzzo, Matteo, Tonna, Paolo, Ossola, Maria Lidia, Gerra, Claudia, Carmassi, Ivan, Cremone, Barbara, Carpita, Nicoletta, Girardi, Marianna, Frascarelli, Antonio, Buzzanca, Roberto, Brugnoli, Anna, Comparelli, Valentina, Corigliano, Giorgio, Di Lorenzo, Cinzia, Niolu, Michele, Ribolsi, Giulio, Corrivetti, Giammarco, Cascino, Gianfranco, del Buono, Simone, Bolognesi, Andrea, Fagiolini, Arianna, Goracci, Silvio, Bellino, Cristiana, Montemagni, Claudio, Brasso, Galderisi, S., Rucci, P., Mucci, A., Rossi, A., Rocca, P., Bertolino, A., Aguglia, E., Amore, M., Bellomo, A., Bozzatello, P., Bucci, P., Carpiniello, B., Collantoni, E., Cuomo, A., Dell'Osso, L., Di Fabio, F., Di Giannantonio, M., Gibertoni, D., Giordano, G. M., Marchesi, C., Monteleone, P., Oldani, L., Pompili, M., Roncone, R., Rossi, R., Siracusano, A., Vita, A., Zeppegno, P., Maj, M., Catapano, F., Piegari, G., Aiello, C., Brando, F., Giuliani, L., Pietrafesa, D., Papalino, M., Mercadante, G., Di Palo, P., Barlati, S., Deste, G., Valsecchi, P., Pinna, F., Olivieri, B., Manca, D., Signorelli, M. S., Poli, L. F., De Berardis, D., Fraticelli, S., Corbo, M., Pallanti, S., Altamura, M., Carnevale, R., Malerba, S., Calcagno, P., Zampogna, D., Corso, A., Giusti, L., Salza, A., Ussorio, D., Talevi, D., Socci, V., Pacitti, F., de Bartolomeis, A., Gramaglia, C., Gambaro, E., Gattoni, E., Favaro, A., Tenconi, E., Meneguzzo, P., Tonna, M., Ossola, P., Gerra, M. L., Carmassi, C., Cremone, I., Carpita, B., Girardi, N., Frascarelli, M., Buzzanca, A., Brugnoli, R., Comparelli, A., Corigliano, V., Di Lorenzo, G., Niolu, C., Ribolsi, M., Corrivetti, G., Cascino, G., Del Buono, G., Bolognesi, S., Fagiolini, A., Goracci, A., Bellino, S., Montemagni, C., Brasso, C., di Giannantonio, M., Fusar Poli, L., del Buono, G., Galderisi S., Rucci P., Mucci A., Rossi A., Rocca P., Bertolino A., Aguglia E., Amore M., Bellomo A., Bozzatello P., Bucci P., Carpiniello B., Collantoni E., Cuomo A., Dell'osso L., Di Fabio F., Di Giannantonio M., Gibertoni D., Giordano G.M., Marchesi C., Monteleone P., Oldani L., Pompili M., Roncone R., Rossi R., Siracusano A., Vita A., Zeppegno P., Maj M., Catapano F., Piegari G., Aiello C., Brando F., Giuliani L., Pietrafesa D., Papalino M., Mercadante G., Di Palo P., Barlati S., Deste G., Valsecchi P., Pinna F., Olivieri B., Manca D., Signorelli M.S., Poli L.F., De Berardis D., Fraticelli S., Corbo M., Pallanti S., Altamura M., Carnevale R., Malerba S., Calcagno P., Zampogna D., Corso A., Giusti L., Salza A., Ussorio D., Talevi D., Socci V., Pacitti F., de Bartolomeis A., Gramaglia C., Gambaro E., Gattoni E., Favaro A., Tenconi E., Meneguzzo P., Tonna M., Ossola P., Gerra M.L., Carmassi C., Cremone I., Carpita B., Girardi N., Frascarelli M., Buzzanca A., Brugnoli R., Comparelli A., Corigliano V., Di Lorenzo G., Niolu C., Ribolsi M., Corrivetti G., Cascino G., Del Buono G., Bolognesi S., Fagiolini A., Goracci A., Bellino S., Montemagni C., and Brasso C.

Subjects
Schizophrenia, everyday life skills, functional capacity, internalized stigma, network analysis, personal resources, psychopathology, real-life functioning, recovery, Closeness, Context (language use), 03 medical and health sciences, 0302 clinical medicine, Betweenness centrality, medicine, network analysi, Everyday life, Baseline (configuration management), personal resource, Research Reports, medicine.disease, 030227 psychiatry, Psychiatry and Mental health, Settore MED/25, everyday life skill, Pshychiatric Mental Health, Psychology, Centrality, 030217 neurology & neurosurgery, Psychopathology, Clinical psychology
Abstract

Improving real-life functioning is the main goal of the most advanced integrated treatment programs in people with schizophrenia. The Italian Network for Research on Psychoses previously explored, by using network analysis, the interplay among illness-related variables, personal resources, context-related factors and real-life functioning in a large sample of patients with schizophrenia. The same research network has now completed a 4-year follow-up of the original sample. In the present study, we used network analysis to test whether the pattern of relationships among all variables investigated at baseline was similar at follow-up. In addition, we compared the network structure of patients who were classified as recovered at follow-up versus those who did not recover. Six hundred eighteen subjects recruited at baseline could be assessed in the follow-up study. The network structure did not change significantly from baseline to follow-up, and the overall strength of the connections among variables increased slightly, but not significantly. Functional capacity and everyday life skills had a high betweenness and closeness in the network at follow-up, as they had at baseline, while psychopathological variables remained more peripheral. The network structure and connectivity of non-recovered patients were similar to those observed in the whole sample, but very different from those in recovered subjects, in which we found few connections only. These data strongly suggest that tightly coupled symptoms/dysfunctions tend to maintain each other's activation, contributing to poor outcome in schizophrenia. Early and integrated treatment plans, targeting variables with high centrality, might prevent the emergence of self-reinforcing networks of symptoms and dysfunctions in people with schizophrenia.

Published
2020

45. Clara Sereni. Sconfinamenti e ritorni

Author

Francesca Caputo, Barenghi, M, Garbo, R, Manghetti, G, Centovalli, B, Gambaro, E, Testa, E, Scriccioli, PV, Caputo, F, Farina, F, and Silvestri, F

Subjects
Clara Sereni, organizzazione testuale, L-FIL-LET/11 - LETTERATURA ITALIANA CONTEMPORANEA
Abstract

L'intervento prende in esame l'organizzazione testuale per lasse, tessere dei libri dell'autrice, variamente disposte a costruire comunque un insieme coerente e il ritorno di libro in libro di figure, oggetti, temi e linguaggi.

Published
2021

46. First-episode Psychosis and Migration in Italy: Results from a Study in the Italian Mental Health Services (Pep-Ita Study)

Author

Marco Rigatelli, Viviana Storbini, Ilaria Tarricone, Mauro Braca, Carla Gramaglia, Silvia Ferrari, Vanna Berlincioni, Mario Altamura, Robin M. Murray, Alessio Ceregato, Roberto Muratori, Domenico Berardi, Francesca Podavini, Bernardo Carpiniello, Craig Morgan, Marta Di Forti, Orlando Todarello, Giuseppe D’Andrea, Giuseppe Barrasso, Corinna Reggianini, D. Primavera, Patrizia Zeppegno, Eleonora Gambaro, Mario Luciano, Tarricone I., D'Andrea G., Storbini V., Braca M., Ferrari S., Reggianini C., Rigatelli M., Gramaglia C., Zeppegno P., Gambaro E., Luciano M., Ceregato A., Altamura M., Barrasso G., Primavera D., Carpiniello B., Todarello O., Berlincioni V., Podavini F., Morgan C., Murray R.M., Di Forti M., Muratori R., and Berardi D.

Subjects
Adult, Mental Health Services, Psychosis, medicine.medical_specialty, Epidemiology, First-episode psychosis, Migrants, Pathway to care, Psychotic Disorder, 03 medical and health sciences, 0302 clinical medicine, First-episode psychosi, First episode psychosis, medicine, Humans, 030212 general & internal medicine, Prospective Studies, Psychiatry, Prospective cohort study, Health needs, Transients and Migrants, Original Paper, business.industry, Public health, Mental Health Service, Public Health, Environmental and Occupational Health, Migrant, Emergency department, medicine.disease, Mental health, 030227 psychiatry, Prospective Studie, Italy, Psychotic Disorders, business, Psychosocial, Human
Abstract

Background: Migrants present high rates of psychosis. A better understanding of this phenomenon is needed. Methods: We conducted a multicentre First-Episode Psychosis (FEP) prospective study over two years (January 2012–December 2013) to evaluate first-generation migrants presenting with FEP at the participating Community Mental Health Centers (CMHCs). Results: 109 FEP migrants were identified. Almost half of them were highly educated, employed and in a stable affective relationship. The average age was 32.8 (± 9.8) years, and the average length of stay in Italy was 8.6 (± 8.8) years. About 2/3 of patients were referred to CMHCs following Emergency Department access or psychiatric admission. Conclusions: Our finding of a “high functioning portrait” of FEP migrants allow us to hypothesize that a high burden of negative psychosocial factors is likely to be needed for the FEP onset. Furtherly, mental health services should implement more appropriate resources and organizational methods to respond to migrants’ health needs.

Published
2021

47. Massini liturgico e aneddotico

Author

Barenghi, M, Turchetta, G, Gambaro, E, Rosa, G, Cenati, G, Novelli, M, Sergio, G, Petruzzi, MS, Barenghi, M, Ghidinelli, S, Gallarini, L, Raccis, G, Daino, L, Fiori, U, Porcelli, T, Caputo, F, Sullam, S, Strazzeri, G, Galbiati, W, Dubini, P, Pallotta, V, Falcetto, B, Cosat, P, Terreni, A, Cesana, R, Parise, S, and Spinazzola, V

Subjects
Lehman Trilogy, Massini, Stefano, Piccolo Teatro, teatro, Moro, Aldo, L-FIL-LET/11 - LETTERATURA ITALIANA CONTEMPORANEA
Abstract

Drammaturgo, narratore, affabulatore, Massini affronta temi grandi e piccoli della realtà contemporanea ritagliando storie e teatralizzandole: sia nella lunga saga della famiglia Lehman, sia negli episodi esemplari raccontati in pochi minuti, lo strumento decisivo è sempre la modulazione recitante della voce.

Published
2019

48. Premorbid academic and social functioning in patients with schizophrenia and its associations with negative symptoms and cognition

Author

Bucci, P., Galderisi, S., Mucci, A., Rossi, A., Rocca, P., Bertolino, A., Aguglia, E., Amore, M., Andriola, I., Bellomo, A., Biondi, M., Cuomo, A., Dell'Osso, L., Favaro, A., Gambi, F., Giordano, G. M., Girardi, P., Marchesi, C., Monteleone, P., Montemagni, C., Niolu, C., Oldani, L., Pacitti, F., Pinna, F., Roncone, R., Vita, A., Zeppegno, P., Maj, M., Patriarca, Sara, Pietrafesa, Daria, Aiello, Carmen, Longo, Luisa, Barone, Marina, Romano, Raffaella, Atti, Anna Rita, Barlati, Stefano, Deste, Giacomo, Valsecchi, Paolo, Carpiniello, Bernardo, Tusconi, Massimo, Puddu, Laura, Signorelli, Maria Salvina, Cannavò, Dario, Minutolo, Giuseppe, Corbo, Mariangela, Montemitro, Chiara, Baroni, Gaia, Altamura, Mario, La Montagna, Maddalena, Carnevale, Raffaella, Murri, Martino Belvederi, Calcagno, Pietro, Bugliani, Michele, Pizziconi, Giulia, Logozzo, Francesca, Rossi, Rodolfo, Giusti, Laura, Salza, Anna, Malavolta, Maurizio, Orsenigo, Giulia, Grassi, Silvia, De Bartolomeis, Andrea, Gramaglia, Carla, Gattoni, Eleonora, Gambaro, Eleonora, Tenconi, Elena, Ferronato, Luisa, Collantoni, Enrico, Tonna, Matteo, Ossola, Paolo, Gerra, Maria Lidia, Carmassi, Claudia, Cremone, Ivan Mirko, Carpita, Barbara, Buzzanca, Antonio, Girardi, Nicoletta, Frascarelli, Marianna, Del Casale, Antonio, Comparelli, Anna, Corigliano, Valentina, Siracusano, Alberto, Di Lorenzo, Giorgio, Ribolsi, Michele, Corrivetti, Giulio, Bartoli, Luca, Del Buono, Gianfranco, Fagiolini, Andrea, Bolognesi, Simone, Goracci, Arianna, Mancini, Irene, Bava, Irene, Cardillo, Simona, Bucci P., Galderisi S., Mucci A., Rossi A., Rocca P., Bertolino A., Aguglia E., Amore M., Andriola I., Bellomo A., Biondi M., Cuomo A., dell'Osso L., Favaro A., Gambi F., Giordano G.M., Girardi P., Marchesi C., Monteleone P., Montemagni C., Niolu C., Oldani L., Pacitti F., Pinna F., Roncone R., Vita A., Zeppegno P., Maj M., Patriarca S., Pietrafesa D., Aiello C., Longo L., Barone M., Romano R., Atti A.R., Barlati S., Deste G., Valsecchi P., Carpiniello B., Tusconi M., Puddu L., Signorelli M.S., Cannavo D., Minutolo G., Corbo M., Montemitro C., Baroni G., Altamura M., La Montagna M., Carnevale R., Murri M.B., Calcagno P., Bugliani M., Pizziconi G., Logozzo F., Rossi R., Giusti L., Salza A., Malavolta M., Orsenigo G., Grassi S., De Bartolomeis A., Gramaglia C., Gattoni E., Gambaro E., Tenconi E., Ferronato L., Collantoni E., Tonna M., Ossola P., Gerra M.L., Carmassi C., Cremone I.M., Carpita B., Buzzanca A., Girardi N., Frascarelli M., Del Casale A., Comparelli A., Corigliano V., Siracusano A., Di Lorenzo G., Ribolsi M., Corrivetti G., Bartoli L., Del Buono G., Fagiolini A., Bolognesi S., Goracci A., Mancini I., Bava I., Cardillo S., Bucci, P., Galderisi, S., Mucci, A., Rossi, A., Rocca, P., Bertolino, A., Aguglia, E., Amore, M., Andriola, I., Bellomo, A., Biondi, Maria, Cuomo, Anna, Dell'Osso, L., Favaro, A., Gambi, F., Giordano, G. M., Girardi, P., Marchesi, C., Monteleone, P., Montemagni, C., Niolu, C., Oldani, L., Pacitti, F., Pinna, F., Roncone, R., DE VITA, Anna, Zeppegno, P., Maj, M., Patriarca, Sara, Pietrafesa, Daria, Aiello, Carmen, Longo, Luisa, Barone, Marina, Romano, Raffaella, Atti, Anna Rita, Barlati, Stefano, Deste, Giacomo, Valsecchi, Paolo, Carpiniello, Bernardo, Tusconi, Massimo, Puddu, Laura, Signorelli, Maria Salvina, Cannavò, Dario, Minutolo, Giuseppe, Corbo, Mariangela, Montemitro, Chiara, Baroni, Gaia, Altamura, Mario, La Montagna, Maddalena, Carnevale, Raffaella, Murri, Martino Belvederi, Calcagno, Pietro, Bugliani, Michele, Pizziconi, Giulia, Logozzo, Francesca, Rossi, Rodolfo, Giusti, Laura, Salza, Anna, Malavolta, Maurizio, Orsenigo, Giulia, Grassi, Silvia, De Bartolomeis, Andrea, Gramaglia, Carla, Gattoni, Eleonora, Gambaro, Eleonora, Tenconi, Elena, Ferronato, Luisa, Collantoni, Enrico, Tonna, Matteo, Ossola, Paolo, Gerra, Maria Lidia, Carmassi, Claudia, Cremone, Ivan Mirko, Carpita, Barbara, Buzzanca, Antonio, Girardi, Nicoletta, Frascarelli, Marianna, Del Casale, Antonio, Comparelli, Anna, Corigliano, Valentina, Siracusano, Alberto, Di Lorenzo, Giorgio, Ribolsi, Michele, Corrivetti, Giulio, Bartoli, Luca, Del Buono, Gianfranco, Fagiolini, Andrea, Bolognesi, Simone, Goracci, Arianna, Mancini, Irene, Bava, Irene, Cardillo, Simona, Biondi, M., Cuomo, A., Vita, A., and Casale, Antonio

Subjects
Male, avolition, Severity of Illness Index, cognitive functioning, 0302 clinical medicine, Cognition, Academic Performance, Medicine, Psychopathology, Depression, primary negative symptoms, Middle Aged, Psychiatric Status Rating Scale, avolition, cognitive functioning, poor emotion expression, premorbid adjustment, primary negative symptoms, poor emotion expression, premorbid adjustment, Psychiatry and Mental Health, Memory, Short-Term, Schizophrenia, Female, Schizophrenic Psychology, medicine.symptom, Psychosocial, Social Adjustment, Clinical psychology, Human, Adult, primary negative symptom, 03 medical and health sciences, Cognition Disorder, Memory, Social cognition, Humans, Cognitive Dysfunction, Cognitive skill, Social Behavior, Aged, Cognition Disorders, Motivation, Psychiatric Status Rating Scales, Settore MED/25 - Psichiatria, Avolition, business.industry, medicine.disease, 030227 psychiatry, Short-Term, business, Neurocognitive, 030217 neurology & neurosurgery
Abstract

Objective The study aimed to explore premorbid academic and social functioning in patients with schizophrenia, and its associations with the severity of negative symptoms and neurocognitive impairment. Method Premorbid adjustment (PA) in patients with schizophrenia was compared to early adjustment in unaffected first-degree relatives and healthy controls. Its associations with psychopathology, cognition, and real-life functioning were investigated. The associations of PA with primary negative symptoms and their two factors were explored. Results We found an impairment of academic and social PA in patients (P ≤ 0.000001) and an impairment of academic aspects of early adjustment in relatives (P ≤ 0.01). Patients with poor PA showed greater severity of negative symptoms (limited to avolition after excluding the effect of depression/parkinsonism), working memory, social cognition, and real-life functioning (P ≤ 0.01 to ≤0.000001). Worse academic and social PA were associated with greater severity of psychopathology, cognitive impairment, and real-life functioning impairment (P ≤ 0.000001). Regression analyses showed that worse PA in the academic domain was mainly associated to the impairment of working memory, whereas worse PA in the social domain to avolition (P ≤ 0.000001). Conclusion Our findings suggest that poor early adjustment may represent a marker of vulnerability to schizophrenia and highlight the need for preventive/early interventions based on psychosocial and/or cognitive programs.

Published
2018

49. L’autoritratto di una generazione

Author

BARENGHI, MARIO LUIGI, Turchetta, G, Pischedda, B, Spianzzola, V, Cosa, P, Novelli, M, Cenati, G, Sergio, G, Falcetto, B, Porcelli, T, Speciale, A, Rosa, G, Gallarini, L, Gambaro E, Interdonato, P, Palieri, MS, Barenghi, M, Giovannetti, P, Fiori, U, Dubini, P, Galbiati, W, Zapparoli, M, Moretti, D, Maccarelli, L, Attanasio, P, Pallotta, W, Bona, F, Daino, L, Petruzzi, MS, Terreni, A, Mussinelli, C, Sullam, S, Cesana, R, Parise, F, and Spinazzola, V

Subjects
Edoardo Albinati, generazioni letterarie, memorialistica, narrativa, L-FIL-LET/11 - LETTERATURA ITALIANA CONTEMPORANEA
Abstract

Né vera e propria narrazione romanzesca, né autofiction, "La scuola cattolica" di Edoardo Albinati costituisce per molti aspetti il libro di un'intera generazione; ma questo non solo per le accurate ricostruzioni storico-sociali e per il tentativo di ritrarre il processo di formazione di un'intera mentalità. È infatti soprattutto nella sua prolissità e dispersione che il testo sembra rispecchiare le difficoltà degli ex baby-boomers nel trasmettere ai propri figli il senso e l'eredità di una esperienza.

Published
2017

50. Gli adorati arricchiti di Edoardo Nesi

Author

BARENGHI, MARIO LUIGI, Spinazzola, V, Rosa, G, Giovannetti, P, Clerici, L, Pischedda, B, Cenati, G, Cerutti, L, Gambaro, E, Rollo, A, Ghidinelli, S, Turchetta, G, Barenghi. M, Daino, L, Carnero, R, Interdonato, P, Petruzzi, MS, Bona, F, Coyaud, S, Fiori, U, Dubini, P, Palieri, MS, Cesana, R, de Rosa, D, Lepri, L, Novelli, M, Cadili, A, Barbisan, I, Gambaro, M, Attanasio, P, Salis, S, Moretti, D, Terreni, A, Massinelli, C, Parise, S, Sullam, S, Cardone, R, Spimazzola, V., and Barenghi, M

Subjects
Fiction e non-fiction, Nesi, Edoardo, Letteratura e industria, L-FIL-LET/11 - LETTERATURA ITALIANA CONTEMPORANEA, Narrativa
Abstract

La parabola di Edoardo Nesi, scrittore che a lungo si è diviso tra il mondo delle lettere e quello imprenditoriale, è un caso pressoché unico nel panorama letterario nazionale: la sua "doppia vita" gli ha però permesso di raccontare dall'interno, in romanzi che sono tutti variazioni su un unico tema, l'ascesa e la caduta di un distretto industriale.

Published
2013

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