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This interventional study was designed to evaluate the effectiveness of buzz session teaching in large groups and assess undergraduate medical students' perceptions of the buzz session teaching method. The study involved 100 first-year medical students divided into two groups, i.e., group I as "buzz first" and group II as "didactic first" comprising 50 students each. The topic "Physiology of the Cerebellum" was taught to group I through a buzz session and to group II through a didactic lecture. After a week, group I received a didactic lecture on the topic "Anterolateral Pathway in the Spinal Cord," whereas group II was taught the same by a buzz session. The students of both groups underwent a multiple choice question exam related to the taught topic immediately and again after 15 days of the teaching session. All students were provided feedback on a five-point Likert scale for the buzz session. According to students' perceptions, buzz sessions boosted communication skills and confidence levels by 94.8% and 96.3%, respectively. Of the students, 93.7% felt that the buzz session helped them retain more information and 94.1% thought they made the classroom environment more lively. More buzz sessions were desired by 94.8% of the participants. There was no difference in the marks gained for the acquired topics using buzz sessions and didactic lectures as teaching methods (P > 0.05). The students scored more marks in the tests taken after the buzz session than after the didactic lecture at 15 days of instruction (P < 0.05). The study concluded that students enjoyed the buzz session teaching method. The buzz session increased short-term retention. NEW & NOTEWORTHY: In this current interventional study, we assessed the effectiveness of a buzz session as a novel teaching tool for large-group physiology instruction in first-year undergraduate medical students. Furthermore, we assessed student responses to see how the buzz session was perceived. Experimental evidence indicates that the buzz sessions led to greater retention after 15 days than the didactic lecture approach for physiology teaching in a preclinical context. [ABSTRACT FROM AUTHOR]

Background: Peripheral arterial disease (PAD) generally occurs as a result of progressive narrowing of arteries within the lower extremities and is a manifestation of systemic atherosclerosis. We define PAD with the aid of using the dimension ankle-brachial index (ABI) which is the most accurate tool and determination of ABI is a simple non-invasive procedure that can be easily performed on an outpatient basis. The cut-off point for diagnosis of peripheral arterial disease (PAD) & cardiovascular risk is ABI ≤ 0.90 or ≥ 1.30. Materials and Methods: This cross sectional study involves 47 newly diagnosed hypertensive patients of age between 30-50 years. Anthropometric measurements and ABI of all the patients were done in the research lab of the Physiology department. The ABI measurements were performed by using an automated oscillometric device (Watch BP Office, Microlife, Widnau, Switzerland). In this procedure, the blood pressure was measured simultaneously on both arms followed by both ankles in the supine position. Results: In our study out of 47 patients, 31 (66.0%) were male and 16 (34.0%) were female of mean age 43.79±6.82 years. The prevalence of deranged ABI in the present study was 10.64% according to Right ABI, while it was 6.38% according to Left ABI. A significant correlation was found for ABI in the Right ankle with SBP in the right upper limb (P=0.013) & both right and left lower limb (P˂0.001 & P=0.028 respectively), while a significant correlation was also found for Left ABI with SBP in both right and left upper limbs (P=0.007 & P=0.003 respectively). We also found that 29.8% of the subjects have a low normal value of ABI (i.e., between 0.9-1.1), this is significant, even in asymptomatic patients, for Peripheral Arterial Disease (PAD). Conclusion: So we can conclude that in newly diagnosed hypertensive patients, ABI are valuable tools for early detection of cardiovascular damage. By identifying subclinical changes before symptoms arise, healthcare providers can implement early, targeted interventions to manage hypertension more effectively and reduce the risk of long-term complications. [ABSTRACT FROM AUTHOR]

Background: The study aims to assess the heart rate variability in nondialysis chronic kidney disease patients. Materials and Methods: This was a cross-sectional study, carried out in the Department of Physiology, Dr RMLIMS, Lucknow. 102 patients in the age group of 30-60 years, having chronic kidney disease but not on dialysis were taken from the OPD of Nephrology. Samples were collected and serum was analyzed for lab parameters like creatinine, and blood urea. eGFR was calculated. HRV of the patient was done in the physiology department. Results: A total of 102 patients fulfilling both criteria were enrolled in the study. The mean age was 45.44±11.13 years. Males constituted of 65.7% of the study population, while female were mere 34.3%. In terms of Blood pressure, SBP and DBP of the study population were 140.92±20.75 mmHg and 82.32±15.13 mmHg. Respiratory rate was 14.28±2.56 breaths per minute. At the first visit, kidney function was accessed using Urea, Creatinine, and eGFR and was recorded as 67.78±33.97 mg/dL, 2.82±1.73 mg/dL, and 36.35±24.58 respectively. Majority of the patients had reduced HRV (73.5%), while the remaining had HRV within the normal range (26.5%). Conclusion: HRV, a non-invasive tool can be used for assessment of autonomic dysfunction in chronic kidney disease who are not on dialysis. Lower HRV has been associated with adverse outcomes in end-stage renal disease (ESRD). Hence the estimation of LF/HF can provide prognostic information on CKD progression and in its management. [ABSTRACT FROM AUTHOR]

Context: "Foundation course" is an orientation program for MBBS students at time of entry into medical college. Aims: To study the MBBS student's perception of relevance and level of confidence in application of skills acquired in foundation course and its predictors. Settings and Design: A cross sectional study was done among second year MBBS students at a medical college in central Uttar Pradesh, India. Methods and Material: Data was collected online using a Google form over 1 month. About 97 (out of 200) students participated in the study. Final analysis was done for 94 responses. Statistical Analysis Used: Chi Square test for proportions. Results: Overall 83% students found foundation course to be relevant. Sessions on professional development & ethics (94.6%), biomedical waste management (94.6%), social responsibility of doctors (91.5%), communication skill (93.6%), role and responsibilities of Indian Medical Graduate (93.6%), universal precautions (91.5%), immunisation (91.5%) and assessing E –resource (90.4%) were rated as most relevant. Computer skills and sports/extra-curricular activities were perceived as non-relevant by 29% and 16% students respectively. Overall 61% students were confident about application of knowledge/skills acquired in the foundation course. A significant difference was observed for gender and medium of education with regards to level of confidence in application of certain skills/knowledge. Conclusions: Foundation course was perceived as relevant by most students. However, level of confidence with regards to application of skills/knowledge was found to be variable with significant difference for some variables. [ABSTRACT FROM AUTHOR]

Background: Viewing of visual imagery of forest or nature is known for producing physiological and psychological relaxation of mind and body. Nature surroundings are colourful and vary from green of plants, blue of water and red, orange, yellow and violet of flowers. These coloured imageries also known to affect our emotion; may lead to joy, sorrow, happiness grief etc. Heart Rate Variability (HRV) indexes through vagal activity the autonomic responses and thereby affects our emotions and behavioural outcome. This study is planned to assess the colour effects of visual imagery of coloured rose flowers on HRV in males and females for red, blue, green, indigo, yellow, orange and violet colours. Methodology: The Heart Rate Variability analysis was conducted on Power Lab AD Instruments, Australia in thirty healthy individuals (15 males and 15 females), aged between 20 to 40 years. Results: We observed variation in autonomic response to different colours in males and females on Heart Rate Variability assessment. There was augmentation of sympathetic drive on viewing of red, orange and violet colour roses in males and that of blue and violet colours in females. The visual imagery of blue, green, indigo and yellow coloured roses in males and red, green, indigo, yellow' and orange coloured in females produced a parasympathetic influence on Heart Rate Variability. Conclusion: Colours affects HRV and thereby can influence our emotional and behavioural responses in our daily life. Adapting to coloured surrounding of choice at workplace and at home may influence our work output and productivity as well produce physical and mental wellbeing. [ABSTRACT FROM AUTHOR]

Background and Aim: Vaccination time may provide an opportunity to advance immunogenicity in terms of the immune system's circadian nature. This analytical study was planned to determine the impact of forenoon and afternoon administration of the COVID-19 vaccine to adults on the magnitude of antibody response., Method: A total of 33 healthy adults with no history of COVID-19 infection or any other disease participated in the study. They were allotted a forenoon (900-1200 hours) or afternoon (1200-500 hours) slot for vaccination. They were categorized as a forenoon or afternoon group, with 16 subjects in the forenoon and 17 in the afternoon group. With the consent of the participants, a blood sample was collected before vaccination, 30 days after the first and 30 days after the second dose of vaccination from all the subjects. The antibody titer response was measured using a commercial semi-quantitative assay, SARS-CoV-2 IgG II., Results: The baseline antibody titer against COVID-19 was 51.41 ± 22.22 AU/mL and 53.21 ± 15.67 AU/mL in the forenoon and afternoon groups, respectively, which increased to 15773.00 ± 3231.41 AU/mL and 12970.82 ± 7608.00 AU/mL after 30 days of the first dose of the COVID-19 vaccine in the forenoon and afternoon groups, respectively. This further increased to 37007.00 ± 1697.75 AU/mL and 38012.00 ± 14001.16 AU/mL after 30 days of the second dose of the COVID-19 vaccine in the forenoon and afternoon groups, respectively. There was no difference in antibody response in subjects with forenoon and afternoon vaccinations. There was no significant difference in antibody titer in males vs. females. The study reported that antibody titers decreased with increasing age and BMI of participants., Conclusion: The time of the day of vaccination does not impact the immune response to COVID-19, but age and BMI are important factors to consider during vaccination against SARS-CoV-2 in the adult population., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institute Ethics Committee of Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow issued approval letter no. 326 dated 23/04/2022, IEC no. 29/22. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: This study received a grant from the Indian Council of Medical Research as per sanction letter no. 55/11/2022-PHY/BMS dated 30/01/2023. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Gangwar et al.)

Lockdown was implemented throughout the world in March 2020 to control the spread of covid-19 infection. It affected the mental health of people in various ways. This web-based cross-sectional survey was conducted in the general population of India with an aim to evaluate the mental health of the healthy individuals in the later stage of the lockdown period. Data on socio-demographic factors, anxiety, depression (HADS scale), perceived stress (PSS scale), insomnia (insomnia severity index), subjective psychological feeling of well-being (WHO-5 well-being Index), and attitude towards covid-19 (7-point Likert scale) was collected. Univariate regression analysis and Karl Pearson's correlation were used to analyze the correlation of mental health abnormalities with socio-demographic factors. 119 subjects of mean age of 36.03 ± 18.04 years took part in the study. Their average number of days of stay at home during the lockdown and the average number of days of the lifestyle changes was 49.07 ± 31.92 and 61.39 ± 20.03 days, respectively. Depression, anxiety, stress, and clinical insomnia due to covid-19 were reported in 13.45%, 10.92%, 14.29%, and 11.76% subjects, respectively. There was a significant correlation of depression, anxiety, stress, and WHO-5 well-being score with age, socio-economic status, and the average number of days of the change in lifestyle due to the COVID-19 pandemic (P < 0.05). Therefore, the study concluded that the abnormalities of mental health were less prevalent in the older age group and lower socioeconomic status in the later phase of lockdown., Competing Interests: None., (IJPPP Copyright © 2021.)