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This paper demonstrates a novel approach to assembling homogeneous molecularly imprinted polymers (MIPs) based on mimicking multiple hydrogen bonds between nucleotide bases by preparing acyclovir (ACV) as a template and using coatings grafted on silica supports. (1)H NMR studies confirmed the AAD-DDA (A for acceptor, D for donor) hydrogen-bond array between template and functional monomer, while the resultant monodisperse molecularly imprinted microspheres (MIMs) were evaluated using a binding experiment, high performance liquid chromatography (HPLC), and solid phase extraction. The Langmuir isothermal model and the Langmuir-Freundlich isothermal model suggest that ACV-MIMs have more homogeneous binding sites than MIPs prepared through normal imprinting. In contrast to previous MIP-HPLC columns, there were no apparent tailings for the ACV peaks, and ACV-MIMs had excellent specific binding properties with a Ka peak of 3.44 × 10(5)M(-1). A complete baseline separation is obtained for ACV and structurally similar compounds. This work also successfully used MIMs as a specific sorbent for capturing ACV from serum samples. The detection limit and mean recovery of ACV was 1.8 ng/mL(-1) and 95.6%, respectively, for molecularly imprinted solid phase extraction coupled with HPLC. To our knowledge, this was the first example of MIPs using AAD-DDA hydrogen bonds.

The multi-channel scanning imager is one of the main payloads of a Geostationary earth orbit satellite of China, which observe multi spectrum from earth. Passive thermal control was applied to decrease temperature rise when solar intrusion at midnight, and heat compensation was made to decrease thermal fluctuation in one orbit. Effort was focused on the scanning mechanism for its relatively strict temperature gradient requirement. In order to validate thermal control scheme, thermal balance experiment scheme was planned. Considering the complexity of solar heat flux into sunshade, solar simulator was used to precisely simulate the heat flux variation. Limited to the dimension of vacuum chamber and solar simulator lamp, only the flux into sunshade was simulated by solar simulator, and other parts was simulated by electrical heaters. The solar illuminated region was analysed in order to keep the total heat flux correct. Detailed test process was figured out to carry out two kinds of heat flux simulation. Date were acquired and compared to thermal analysis. Based on experiment condition, thermal model was constructed and modified. From analysis of all the effecting factors, it is find that thermal contact resistance between heatpipes and heat dissipating plate can largely effect the temperature of scanning mechanism. Thermal model of scanning mechanism was detailly constructed including features effecting heat flux absorption and temperature distribution. After modification, the prediction ability of thermal model was enhanced. And optimization of thermal design was made to decrease temperature level and gradient of scanning mechanism. Thermal analyse was done to estimate the optimization, and its effectiveness was validated.

The multi channel scanning imagery radiometer is one of the main payloads of a geostationary earth orbit satellite , which can observe multi spectrum from the earth. The radiometer will endure complicated heat flux environment in orbit, and effective thermal design for the instrument is required in order to ensure high quality scanning image. Based on characteristics of the heat flux in geostationary earth orbit and the unique structure of the radiometer, thermal design characteristic was analyzed, and detailed thermal control design was developed based on numerical analysis. The numerical results verified the validity of thermal control design.