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A novel bromothiophene‐functionalized BF2‐curcuminoid (BTC‐BF2) is synthesized by Knoevenagel condensation reaction. The structure of BTC‐BF2 is determined by 1H‐nuclear magnetic resonance (1H NMR), 13C‐nuclear magnetic resonance (13C NMR), and high‐resolution mass spectrometry (HRMS). Moreover, a nearly coplanar single crystal structure is successfully obtained and form a mesh structure through intermolecular multiple C─H···F hydrogen bond interactions. As expected, as‐prepared BTC‐BF2 exhibits solvent‐dependent photophysical properties in solvents with different polarity and an intense red solid‐state fluorescence. Density functional theory calculations further verify the relationships between its intrinsic electronic features and the photophysical properties. For its potential application aspect, BTC‐BF2 shows a certain ability to generate singlet oxygen under irradiation with 530 nm green light. Moreover, BTC‐BF2 can be utilized as versatile building block to construct novel far‐red or NIR BF2‐curcuminoid complexes for widely biological applications. [ABSTRACT FROM AUTHOR]

Molecular imprinting has emerged as an important and practical technology to create economical and stable synthetic mimics of antibodies and enzymes. It has already found a variety of important applications, such as affinity separation, chemical/biological sensing, disease diagnostics, proteomics, bioimaging, controlled drug release, and catalysis. In the past decade, significant breakthroughs have been made in non-covalently imprinted polymers, from their synthesis through to their applications. In terms of synthesis, quite a few versatile and facile imprinting approaches for preparing MIPs have been invented, which have effectively solved some key issues in molecular imprinting. Additionally, important applications in several areas, such as sensors, proteomics and bioimaging, have been well demonstrated. In this review, we critically and comprehensively survey key recent advances made in the preparation of non-covalently imprinted polymers and their important applications. We focus on the state-of-art of this technology from three different perspectives: fundamentals, synthetic strategies, and applications. We first provide a fundamental basis for molecular imprinting technologies that have been developed, which is extremely helpful for establishing a sound understanding of the challenges in molecular imprinting. Then, we discuss in particular the major breakthroughs within the last ten years (2014–2024), with emphasis on new imprinting approaches, what strengths the breakthroughs can provide, and which new applications the properties of the prepared non-covalently imprinted polymers are fit for. [ABSTRACT FROM AUTHOR]

A novel bromothiophene-functionalized BF 2 -curcuminoid (BTC-BF 2 ) is synthesized by Knoevenagel condensation reaction. The structure of BTC-BF 2 is determined by 1 H-nuclear magnetic resonance ( 1 H NMR), 13 C-nuclear magnetic resonance ( 13 C NMR), and high-resolution mass spectrometry (HRMS). Moreover, a nearly coplanar single crystal structure is successfully obtained and form a mesh structure through intermolecular multiple C─H···F hydrogen bond interactions. As expected, as-prepared BTC-BF 2 exhibits solvent-dependent photophysical properties in solvents with different polarity and an intense red solid-state fluorescence. Density functional theory calculations further verify the relationships between its intrinsic electronic features and the photophysical properties. For its potential application aspect, BTC-BF 2 shows a certain ability to generate singlet oxygen under irradiation with 530 nm green light. Moreover, BTC-BF 2 can be utilized as versatile building block to construct novel far-red or NIR BF 2 -curcuminoid complexes for widely biological applications., (© 2024 Wiley‐VCH GmbH.)