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42 results on '"Gao, Suizhi"'

6. Circulating cell‐free DNA methylation‐based multi‐omics analysis allows early diagnosis of pancreatic ductal adenocarcinoma

Author

Zhao, Guochao, primary, Jiang, Ruijingfang, additional, Shi, Ying, additional, Gao, Suizhi, additional, Wang, Dansong, additional, Li, Zhilong, additional, Zhou, Yuhong, additional, Sun, Jianlong, additional, Wu, Wenchuan, additional, Peng, Jiaxi, additional, Kuang, Tiantao, additional, Rong, Yefei, additional, Yuan, Jie, additional, Zhu, Shida, additional, Jin, Gang, additional, Wang, Yuying, additional, and Lou, Wenhui, additional

Published
2024
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12. Early oral feeding versus nasojejunal early enteral nutrition in patients following pancreaticoduodenectomy: a propensity score-weighted analysis of 428 consecutive patients

Author

Jing, Wei, primary, Wu, Shengyong, additional, Gao, Suizhi, additional, Shi, Xiaohan, additional, Liu, Wuchao, additional, Ren, Yiwei, additional, Ouyang, Liu, additional, Zheng, Kailian, additional, Guo, Shiwei, additional, Wu, Cheng, additional, and Jin, Gang, additional

Published
2023
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13. A novel staging system derived from natural language processing of pathology reports to predict prognostic outcomes of pancreatic cancer: a retrospective cohort study

Author

Li, Bo, primary, Wang, Beilei, additional, Zhuang, Pengjie, additional, Cao, Hongwei, additional, Wu, Shengyong, additional, Tan, Zhendong, additional, Gao, Suizhi, additional, Li, Penghao, additional, Jin, Wei, additional, Shao, Zhuo, additional, Zheng, Kailian, additional, Wu, Lele, additional, Gao, Bai, additional, Wang, Yang, additional, Jiang, Hui, additional, Guo, Shiwei, additional, He, Liang, additional, Yang, Yan, additional, and Jin, Gang, additional

Published
2023
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14. Systemic Immune-Inflammation Index After Neoadjuvant Therapy Predicts the Pathological Response in Patients with Resected Pancreatic Ductal Adenocarcinoma

Author

Shen, Shuo, primary, Zhu, Lingyu, additional, Li, Bo, additional, Yin, Xiaoyi, additional, Shi, Xiaohan, additional, Gao, Suizhi, additional, Wang, Huan, additional, Zhang, Guoxiao, additional, Jing, Wei, additional, Zheng, Kailian, additional, Li, Gang, additional, Guo, Shiwei, additional, and Jin, Gang, additional

Published
2023
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15. Modified artery-first approach for distal pancreatectomy with celiac axis resection

Author

Wang, Huan, primary, Shen, Shuo, additional, Ren, Yiwei, additional, Lin, Xueru, additional, Shi, Xiaohan, additional, Gao, Suizhi, additional, Li, Bo, additional, Yin, Xiaoyi, additional, Zhang, Guoxiao, additional, Liu, Wuchao, additional, Wang, Jian, additional, Han, Jiawei, additional, Zhu, Lingyu, additional, Xu, Xiongfei, additional, Shao, Zhuo, additional, Jing, Wei, additional, Song, Bin, additional, Cheng, Peng, additional, Guo, Shiwei, additional, Zheng, Kailian, additional, and Jin, Gang, additional

Published
2023
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18. Morphomolecular staging to improve stratification of patients with node-negative pancreatic cancer

Author

Shi, Xiaohan, primary, Yin, Xiaoyi, additional, Gao, Suizhi, additional, Li, Bo, additional, Wang, Huan, additional, Wang, Guobin, additional, Zhang, Guoxiao, additional, Shen, Shuo, additional, Liu, Wuchao, additional, Wang, Jian, additional, Han, Jiawei, additional, Ren, Yiwei, additional, Zhu, Lingyu, additional, Xu, Xiongfei, additional, Shao, Zhuo, additional, Zheng, Kailian, additional, Jing, Wei, additional, Song, Bin, additional, Cheng, Peng, additional, Li, Gang, additional, Zhang, Yijie, additional, Jiang, Hui, additional, Guo, Shiwei, additional, and Jin, Gang, additional

Published
2023
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22. Large‐cohort humanized NPI mice reconstituted with CD34 + hematopoietic stem cells are feasible for evaluating preclinical cancer immunotherapy

Author

Xu, Xiongfei, primary, Gu, Haihui, additional, Li, Hongwei, additional, Gao, Suizhi, additional, Shi, Xiaohan, additional, Shen, Jing, additional, Li, Bo, additional, Wang, Huan, additional, Zheng, Kailian, additional, Shao, Zhuo, additional, Cheng, Peng, additional, Cha, Zhanshan, additional, Peng, Siying, additional, Nie, Yongzhan, additional, Li, Zhaoshen, additional, Guo, Shiwei, additional, Qian, Baohua, additional, and Jin, Gang, additional

Published
2022
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24. Additional file 1 of Radiomics nomogram for the preoperative prediction of lymph node metastasis in pancreatic ductal adenocarcinoma

Author

Bian, Yun, Guo, Shiwei, Jiang, Hui, Gao, Suizhi, Shao, Chengwei, Cao, Kai, Fang, Xu, Li, Jing, Wang, Li, Ma, Chao, Zheng, Jianming, Jin, Gang, and Lu, Jianping

Abstract

Additional file 1: Supplementary 1. Image preprocessing. Supplementary 2. Radiomics Features. Supplementary 3. the Least Absolute Shrinkage and Selection Operator (LASSO) Algorithm. Supplementary 4. Decision Curve Analysis (DCA). Supplementary 5. Radiomic Features Selected by LASSO Regularization.

Published
2022
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25. Additional file 2 of Noninvasive detection of pancreatic ductal adenocarcinoma using the methylation signature of circulating tumour DNA

Author

Wu, Huanwen, Guo, Shiwei, Liu, Xiaoding, Li, Yatong, Su, Zhixi, He, Qiye, Liu, Xiaoqian, Zhang, Zhiwen, Yu, Lianyuan, Shi, Xiaohan, Gao, Suizhi, Wang, Huan, Pan, Yaqi, Ma, Chengcheng, Liu, Rui, Dai, Menghua, Jin, Gang, and Liang, Zhiyong

Abstract

Additional file 2: Figure S1. Sample size of tissue samples (A) and plasma sample (B) in Phase I, Phase II and Phase III. The reused samples were showed in dot. Figure S2. Sample sizes of the key categories. Stage I (A) and CA19-9-negative PDAC (B) were shown. Figure S3. Overview of incremental feature selection of PDAC-specific MHB to build PandaX classifiers. Figure S4. Performance of PDAC-CP classifier in differentiating PDAC from CP plasma and covariate analysis. A. ROC of PDACatch classifying PDAC and CP plasma. B. PDACatch scores across different type of samples. In panel B, samples were labelled with cohorts (Train/Validation), pathological types (H: Healthy; CP: chronic pancreatitis) and clinical stages of PDAC (I, II, I-IIA and IIB-IV). For C-F, PDAC-CP classifier’s scores of PDAC and CP plasma samples were grouped by gender (A), age (B), tumour location (C) and tumour size (D). Wilcoxon rank sum test. ns: 0.05 < p

Published
2022
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27. Risk Factors of Positive Resection Margin Differ in Pancreaticoduodenectomy and Distal Pancreatosplenectomy For Pancreatic Ductal Adenocarcinoma: A Study Based On Leeds Pathology Protocol

Author

Li, Bo, primary, Guo, Shiwei, additional, Yin, Xiaoyi, additional, Shi, Xiaohan, additional, Ni, Chenming, additional, Gao, Suizhi, additional, Li, Gang, additional, Ni, Canrong, additional, Jiang, Hui, additional, Lau, Wan Yee, additional, and Jin, Gang, additional

Published
2021
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28. Blood small extracellular vesicles derived miRNAs to differentiate pancreatic ductal adenocarcinoma from chronic pancreatitis

Author

Guo, Shiwei, primary, Qin, Hao, additional, Liu, Ke, additional, Wang, Huan, additional, Bai, Sijia, additional, Liu, Shiyi, additional, Shao, Zhuo, additional, Zhang, Yanan, additional, Song, Bin, additional, Xu, Xiaoya, additional, Shen, Jing, additional, Zeng, Peng, additional, Shi, Xiaohan, additional, Chen, Hao, additional, Gao, Suizhi, additional, Xu, Jiajia, additional, Pan, Yaqi, additional, Xiong, Lei, additional, Li, Fugen, additional, Zhang, Dadong, additional, Jiao, Xiaodong, additional, and Jin, Gang, additional

Published
2021
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29. The Landscape of Genetic Alterations Stratified Prognosis in Oriental Pancreatic Cancer Patients

Author

Guo, Shiwei, primary, Shi, Xiaohan, additional, Gao, Suizhi, additional, Hou, Qunxing, additional, Jiang, Lisha, additional, Li, Bo, additional, Shen, Jing, additional, Wang, Huan, additional, Shen, Shuo, additional, Zhang, GuoXiao, additional, Pan, Yaqi, additional, Liu, Wuchao, additional, Xu, Xiongfei, additional, Zheng, Kailian, additional, Shao, Zhuo, additional, Jing, Wei, additional, Lin, Ling, additional, Li, Gang, additional, and Jin, Gang, additional

Published
2021
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30. Which Factors Are Associated with Positive Resection Margin in Pancreatic Ductal Adenocarcinoma for different surgical procedures? Results Based on a Standard Pathological Evaluation System-Retrospective Cohort Study

Author

Li, Bo, primary, Guo, Shiwei, additional, Shi, Xiaohan, additional, Ni, Chenming, additional, Gao, Suizhi, additional, Li, Gang, additional, Ni, Canrong, additional, Jiang, Hui, additional, Lau, Wan Yee, additional, and Jin, Gang, additional

Published
2021
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31. Nomogram for the Prediction of High-Grade Dysplasia and Invasive Carcinoma in Patients With Intraductal Papillary Mucinous Neoplasms of the Pancreas Based on Variables of Noninvasive Examination

Author

Li, Bo, primary, Shi, Xiaohan, additional, Gao, Suizhi, additional, Shen, Shuo, additional, Bian, Yun, additional, Cao, Kai, additional, Pan, Yaqi, additional, Zhang, Guoxiao, additional, Jiang, Hui, additional, Li, Gang, additional, Guo, Shiwei, additional, and Jin, Gang, additional

Published
2021
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33. Which Factors Are Associated With Positive Resection Margin in Pancreatic Ductal Adenocarcinoma for Different Surgical Procedures? Results Based on a Standard Pathological Evaluation System-retrospective Cohort Study 

Author

Li, Bo, primary, Guo, Shiwei, additional, Shi, Xiaohan, additional, Ni, Chenming, additional, Gao, Suizhi, additional, Li, Gang, additional, Ni, Canrong, additional, Jiang, Hui, additional, Lau, Wan Yee, additional, and Jin, G, additional

Published
2020
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35. Pros and Cons: High Proportion of Stromal Component Indicates Better Prognosis in Patients With Pancreatic Ductal Adenocarcinoma—A Research Based on the Evaluation of Whole-Mount Histological Slides

Author

Li, Bo, primary, Wang, Yang, additional, Jiang, Hui, additional, Li, Baoming, additional, Shi, Xiaohan, additional, Gao, Suizhi, additional, Ni, Canrong, additional, Zhang, Zelin, additional, Guo, Shiwei, additional, Xu, Jun, additional, and Jin, Gang, additional

Published
2020
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38. Single-Cell RNA Sequencing Reveals PD-L1+ Fibroblasts as a Determinant of Immune Exhaustion in Pancreatic Cancer Microenvironment

Author

Zhao, Yi, primary, Guo, Shiwei, additional, Yi, Gang, additional, Xie, Feng, additional, Guo, Yixian, additional, Miao, Yu, additional, Wang, Xie, additional, Gao, Suizhi, additional, Chen, Bangwei, additional, Xu, Xiongfei, additional, Zhang, Guoxiao, additional, Sun, Jianne, additional, Yin, Jianhua, additional, Tsun, Andy, additional, Li, Xiao, additional, Yang, Huanming, additional, Jin, Gang, additional, Li, Bin, additional, and Liu, Xiao, additional

Published
2020
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39. Abstract 1363: Identifying blood exosomal miRNAs as biomarkers in the diagnosis and prognosis of pancreatic ductal adenocarcinoma

Author

Guo, Shiwei, primary, Wang, Huan, additional, Qin, Hao, additional, Zhang, Dadong, additional, Shao, Zhuo, additional, Zhang, Yanan, additional, Song, Bin, additional, Xu, Xiaoya, additional, Shen, Jing, additional, Chen, Zishuo, additional, Shi, Xiaohan, additional, Gao, Suizhi, additional, Pan, Yaqi, additional, Li, Fugen, additional, and Jin, Gang, additional

Published
2019
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41. Early oral feeding versus nasojejunal early enteral nutrition in patients following pancreaticoduodenectomy: a propensity score-weighted analysis of 428 consecutive patients.

Author

Jing W, Wu S, Gao S, Shi X, Liu W, Ren Y, Ouyang L, Zheng K, Guo S, Wu C, and Jin G

Subjects
Humans, Pancreaticoduodenectomy adverse effects, Pancreaticoduodenectomy methods, Retrospective Studies, Propensity Score, Postoperative Complications epidemiology, Postoperative Complications etiology, Postoperative Complications prevention & control, Gastric Emptying, Treatment Outcome, Enteral Nutrition methods, Gastroparesis etiology
Abstract

Background: Notwithstanding that significant medical progress has been achieved in recent years, the optimal nutritional support method following pancreaticoduodenectomy (PD) remains uncertain. This study compared the safety and feasibility of early oral feeding (EOF) with nasojejunal early enteral nutrition (NJEEN) after PD., Methods: A retrospective cohort study was conducted on 428 consecutive patients who underwent PD between August 2018 and December 2020. During the first study phase, the routine postoperative feeding strategy was NJEEN, later replaced by EOF during the second study phase. The primary outcome was the incidence of delayed gastric emptying (DGE) following PD. Propensity score weighting was used to control for confounding factors., Results: Four hundred forty patients underwent PD during the overall study period, with 438 patients aged 18 years and older. Ten patients experienced accidental tube dislodgement or migration and were excluded from the study based on the exclusion criteria. Finally, 211 patients and 217 patients underwent EOF and NJEEN, respectively. After propensity score weighting, it was observed that patients who underwent postoperative EOF experienced a significantly lower DGE (B/C) rate compared to those who underwent postoperative NJEEN [7.38% (31/424) vs. 14.97% (62/413), P =0.0005]. Subgroup analyses according to the presence of soft pancreatic texture yielded consistent results. The EOF group exhibited lower DGE grade, DGE (B/C) rate [5.90% (11/194) vs. 22.07% (43/193), P <0.0001], postoperative gastrointestinal endoscopic intervention rate, and Clavien-Dindo Grade III or higher rate., Conclusions: EOF is superior to NJEEN in reducing the incidence of grade B/C DGE after PD. The EOF procedure is safe and feasible and should be recommended as the optimal postoperative feeding method following PD., (Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.)

Published
2024
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42. Oncological and genetic factors impacting PDX model construction with NSG mice in pancreatic cancer.

Author

Guo S, Gao S, Liu R, Shen J, Shi X, Bai S, Wang H, Zheng K, Shao Z, Liang C, Peng S, and Jin G

Subjects
Animals, Carcinoma, Pancreatic Ductal blood supply, Female, Heterografts, Humans, Immunohistochemistry, Male, Mice, Mice, Inbred NOD, Mice, SCID, Middle Aged, Mutation, Neovascularization, Pathologic, Pancreatic Neoplasms blood supply, Prognosis, Vascular Endothelial Growth Factor A metabolism, Carcinoma, Pancreatic Ductal genetics, Carcinoma, Pancreatic Ductal pathology, Pancreatic Neoplasms genetics, Pancreatic Neoplasms pathology
Abstract

A patient-derived xenograft (PDX) approach, which relies on direct transplantation of tumor specimens into an immunocompromised animal, is a commonly used method for investigating tumor therapy predictions in vivo. This study evaluated influencing factors, including clinical, oncological, and genetic variables, for a pancreatic PDX model in mice. Tumor specimens were obtained from 121 patients with pancreatic ductal adenocarcinoma who underwent surgical resection at the Changhai Pancreatic Surgery Medical Center (Shanghai, China) between April 2016 and February 2017. Pancreatic cancer (PC) samples <3 mm 3 were subcutaneously implanted into the NOD/Shi-scid/IL-2Rγnull (NSG) mice. Once the xenograft reached 300-500 mm 3 or reached 180 d after cell inoculation, the tumor was excised. Part of the tumor was subsequently transplanted to next-generation mice, and another part was analyzed by using immunohistochemistry. Among the 121 patients with PC, tumor xenograft was successfully generated in 86 patients (71.1%). Primary tumor >3.5 cm in size was independently associated with xenograft formation rate. In addition, several enriched mutated genes within the VEGF pathway and higher microvessel density were found in the positive group (with xenograft) compared with the negative group (without xenograft). We concluded that tumor size and mutated VEGF pathway in PC are important factors affecting PDX model construction with NSG mice.-Guo, S., Gao, S., Liu, R., Shen, J., Shi, X., Bai, S., Wang, H., Zheng, K., Shao, Z., Liang, C., Peng, S., Jin, G. Oncological and genetic factors impacting PDX model construction with NSG mice in pancreatic cancer.

Published
2019
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