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2. PREGNANCY OUTCOMES AND NEWBORN CHARACTERISTICS IN WOMEN WITH FOLLICULAR FLUID THYROID AUTOANTIBODIES UNDERGOING ASSISTED REPRODUCTION.

Author

Medenica, Sanja, Garalejic, Eliana, Abazovic, Dzihan, Bukumiric, Zoran, Paschou, Stavroula A., Arsic, Biljana, Vujosevic, Snezana, Medjo, Biljana, and Zarkovic, Milos

Subjects
*PREGNANCY outcomes, *PREGNANCY complications, *MULTIPLE pregnancy, *REPRODUCTIVE technology, *THYROID gland, *AUTOANTIBODIES
Abstract

Background: Higher levels of thyroid autoantibodies in follicular fluid (FF) of thyroid autoimmunity (TAI) positive women are strongly correlated with serum levels and may have effect on the post-implantation embryo development. Literature highlights that levothyroxine (LT4) treatment may attenuate the risk of adverse pregnancy outcomes. The aim of the study was to estimate the pregnancy and newborn outcomes in women with FF thyroid autoantibodies undergoing assisted reproductive technology (ART). Methods: The study population included 24 women with confirmed clinical pregnancy, 8 TAI positive and 16 TAI negative women. LT4 supplementation was applied in 20.8% patients, TAI positive. Results: Pregnancy outcomes were: twin pregnancy rate 41.7%, early miscarriage rate 8.3%, late miscarriage rate 4.2%, preterm birth rate 16.7%, term birth rate 70.8%, live birth rate 96.0%. There was significant difference in serum and in FF TgAbs (p<0.001)between the groups according to TAI, while serum fT3 was lower in the group with TAI (p=0.047). Serum fT4 was higher in LT4 treated group (p=0.005), with TAI, and newborns in this group had higher birth weight (p=0.001) and height (p=0.008). Maternal complications occurred in 23.8% of patients. No congenital malformations in newborns were noted. Conclusions: Thyroid autoantibodies present in FF may have an effect on the post-implantation embryo development, but have no effect on further course of pregnancy. The special benefit of LT4 treatment for successful ART outcome was demonstrated for newborn anthropometric parameters. [ABSTRACT FROM AUTHOR]

Published
2023
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10. Male reproductive health statement (XIIIth international symposium on Spermatology, may 9th-12th 2018, Stockholm, Sweden

Author

Macanovic, Biljana, Vucetic, Milica, Jankovic, Aleksandra, Stancic, Ana, Buzadzic, Biljana, Garalejic, Eliana, Korac, Aleksandra, Korac, Bato, Otasevic, Vesna, Levine, Hagai, Mohri, Hideo, Ekbom, Anders, Ramos, Liliana, Parker, Geoff, Roldan, Eduardo, Jovine, Luca, Koelle, Sabine, Lindstrand, Anna, Immler, Simone, Mortimer, Sharon, Mortimer, David, van der Horst, Gerhard, Ishijima, Sumio, Aneck-Hahn, Natalie, Baldi, Elisabetta, Menkveld, Roelof, Rothmann, Susan, Giwercman, Aleksander, Giwercman, Yvonne, Holmberg, Mats, Kvist, Ulrik, Björndahl, Lars, Holmberg, Rebecka, Arver, Stefan, Flanagan, John, Drevet, Joël, Karolinska Inst, Novum, Ctr Biosci, SE-14183 Huddinge, Sweden, Molecular Medicine and Surgery department, Karolinska Institutet [Stockholm], Department of Animal and Plant Sciences [Sheffield], University of Sheffield [Sheffield], Oozoa Biomedical Inc, Food Standards Agency, Reproductive Medicine Centre, Malmo University Hospital, Andrology Center, Génétique, Reproduction et Développement (GReD), Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Institut National de la Santé et de la Recherche Médicale (INSERM), and Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS)

Subjects
Male reproductive health, Species survival, Spermatozoa, Reproductive Medicine, Urology, 0301 basic medicine, medicine.medical_specialty, Statement (logic), Reproductive medicine, Santé reproductive masculine, [SDV.BDLR.RS]Life Sciences [q-bio]/Reproductive Biology/Sexual reproduction, 03 medical and health sciences, Survie des espèces, Political science, Reproductive biology, medicine, ComputingMilieux_MISCELLANEOUS, [SDV.BDD.GAM]Life Sciences [q-bio]/Development Biology/Gametogenesis, Reproductive health, Medical education, lcsh:R5-920, business.industry, Other Research Radboud Institute for Health Sciences [Radboudumc 0], Les spermatozoïdes, 3. Good health, 030104 developmental biology, [SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunology, Commentary, business, lcsh:Medicine (General)
Abstract

© The Author(s)., [EN]: On the occasion of the XIIIth International Symposium on Spermatology held from 9 to 13 May 2018 in Stockholm (Sweden), participants (guest speakers and audience) collectively felt the need to make a public statement on the general issue of male reproductive health. Our intention is to raise awareness of what we believe is a neglected area of research despite alarming situations around the world. The disclosure strategy desired by the co-authors is to bring it to the attention of the greatest number partly by considering co-publication in the various periodicals dealing with Reproductive Biology and Andrology. BaCA’s editorial office accepted this mission and found it natural that our periodical, the official journal of the French Andrology Society (SALF), should carry this message., [FR]: A l’occasion du XIIIeme Symposium international sur la Spermatologie qui s’est. tenu du 9 au 13 Mai 2018 à Stockholm (Suède), les participants (orateurs invités et l’auditoire) ont ressenti collectivement le besoin de faire une déclaration publique sur la question générale de la santé reproductive masculine. Notre intention est. de mieux faire connaître ce que nous pensons être un domaine de recherche négligé malgré des situations alarmantes dans le monde entier. La stratégie de divulgation souhaitée par les co-auteurs est. de le porter à l’attention du plus grand nombre en envisageant pour partie une co-publication dans les différents périodiques traitant de Reproduction et d’Andrologie. Le bureau éditorial de BaCA, a accepté cette mission et a trouvé naturel que notre périodique, journal officiel de la Société d’Andrologie en Langue Française (SALF) porte ce message.

Published
2018

13. Licheniocin 50.2 and Bacteriocins from Lactococcus lactis subsp. lactis biovar. diacetylactis BGBU1-4 Inhibit Biofilms of Coagulase Negative Staphylococci and Listeria monocytogenes Clinical Isolates

Author

Cirkovic, Ivana, primary, Bozic, Dragana D., additional, Draganic, Veselin, additional, Lozo, Jelena, additional, Beric, Tanja, additional, Kojic, Milan, additional, Arsic, Biljana, additional, Garalejic, Eliana, additional, Djukic, Slobodanka, additional, and Stankovic, Slavisa, additional

Published
2016
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15. Relationship between mid-trimester ultrasound fetal liver length measurements and gestational diabetes mellitus 妊娠中期三个月超声测量的胎儿肝脏长度与妊娠期糖尿病之间的关系

Author

Perovic, Milan, primary, Gojnic, Miroslava, additional, Arsic, Biljana, additional, Pantic, Igor, additional, Stefanovic, Tomislav, additional, Kovacevic, Gordana, additional, Kovacevic, Milica, additional, Garalejic, Eliana, additional, Dugalic, Stefan, additional, Radakovic, Jovana, additional, Babic, Uros, additional, and Isenovic, Esma R., additional

Published
2014
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18. Is Manganese (II) Pentaazamacrocyclic Superoxide Dismutase Mimic Beneficial for Human Sperm Mitochondria Function and Motility?

Author

Otasevic, Vesna, primary, Korac, Aleksandra, additional, Vucetic, Milica, additional, Macanovic, Biljana, additional, Garalejic, Eliana, additional, Ivanovic-Burmazovic, Ivana, additional, Filipovic, Milos R., additional, Buzadzic, Biljana, additional, Stancic, Ana, additional, Jankovic, Aleksandra, additional, Velickovic, Ksenija, additional, Golic, Igor, additional, Markelic, Milica, additional, and Korac, Bato, additional

Published
2013
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