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2,570 results on '"Garcia, Gil"'

1. Assessing light pollution in vast areas: zenith sky brightness maps of Catalonia

Author

Linares, Hector, Ribas, Eduard Masana Salvador J, García-Gil, Manuel, Aubé, Martin, de Miguel, Alejandro Sánchez, and Simoneau, Alexandre

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

Zenith sky brightness maps in the V and B bands of the region of Catalonia are presented in this paper. For creating them we have used the light pollution numerical model Illumina v2. The maps have a sampling of 5x5 km for the whole region with an improved resolution of 1x1 km for one of the provinces within Catalonia, Tarragona. Before creating the final maps, the methodology was tested successfully by comparing the computed values to measurements in nineteen different locations spread out throughout the territory. The resulting maps have been compared to the zenith sky brightness world atlas and also to Sky Quality Meter (SQM) dynamic measurements. When comparing to measurements we found small differences mainly due to mismatching in the location of the points studied, and also due to differences in the natural sky brightness and atmospheric content. In the comparison to the world atlas some differences were expected as we are taking into account the blocking effect of topography and obstacles, and also due to a more precise light sources characterization. The results of this work confirm the conclusion found in other studies that the minimum sampling for studying sky brightness fine details is of 1x1 km. However, a sampling of 5x5 km is interesting when studying general trends, mainly for vast areas, due to the reduction of the time required to create the maps., Comment: 32 pag, 17 figures

Published
2024
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4. The Impact of Lebrikizumab on Vaccine-Induced Immune Responses: Results from a Phase 3 Study in Adult Patients with Moderate-to-Severe Atopic Dermatitis

Author

Jennifer Soung, Vivian Laquer, Joseph F. Merola, Angela Moore, Hany Elmaraghy, Chaoran Hu, Maria Lucia Buziqui Piruzeli, Evangeline Pierce, Esther Garcia Gil, and Abel D. Jarell

Subjects
Atopic dermatitis, IL-13, Lebrikizumab, MCV, Tdap, Vaccine response, Dermatology, RL1-803
Abstract

Abstract Introduction Lebrikizumab, a high-affinity IgG4 monoclonal antibody that selectively inhibits interleukin-13 with high binding affinity and slow dissociation rate, prevents the formation of the interleukin-4Rα/interleukin-13Rα1 heterodimer receptor signaling complex. Here we report the impact of lebrikizumab on responses to two non-live vaccines in adult patients with moderate-to-severe atopic dermatitis (AD). Methods ADopt-VA (NCT04626297) was a double-blind, placebo-controlled, parallel-group, 16-week, phase 3 randomized study to assess the impact of lebrikizumab treatment on non-live vaccine immune responses, and efficacy and safety of lebrikizumab compared with placebo. Eligible patients included adults from 18 to 55 years of age with moderate-to-severe chronic AD who were randomly assigned 1:1 to lebrikizumab 250 mg every 2 weeks or placebo and stratified according to disease severity. The primary endpoints were the development of a booster response to tetanus toxoid and a positive antibody response to meningococcal conjugate vaccine (MCV), 4 weeks after administration of the corresponding vaccine. Results At week 16, 73.6% of patients in the lebrikizumab group (n = 78/106) achieved Tdap booster response compared with 73.4% of patients in the placebo group (n = 58/79). MCV vaccine response was observed in 86.9% of patients in the lebrikizumab group (n = 86/99) and 75.0% of patients in the placebo group (n = 60/80). At week 16, IGA 0,1 with ≥ 2-point improvement from baseline was achieved by 40.6% (n = 51/125) of patients treated with lebrikizumab and 18.9% (n = 23/122) of patients who received placebo (p

Published
2024
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5. Lebrikizumab Improves Quality of Life and Patient-Reported Symptoms of Anxiety and Depression in Patients with Moderate-to-Severe Atopic Dermatitis

Author

Peter A. Lio, April Armstrong, Jan Gutermuth, Audrey Nosbaum, Howard Sofen, Esther Garcia Gil, Marta Casillas, Sherry Chen, Luna Sun, Evangeline Pierce, Hany Elmaraghy, Zach Dawson, and Tiago Torres

Subjects
Anxiety, Atopic dermatitis, Depression, Lebrikizumab, Mental health, Quality of life, Dermatology, RL1-803
Abstract

Abstract Introduction Atopic dermatitis (AD) is a chronic inflammatory skin disease for which signs and symptoms have a negative impact on a patient’s quality of life (QoL) and mental health. Here, we assess the impact of lebrikizumab on QoL and mental health after 16 weeks of treatment in patients with moderate-to-severe AD. Methods Data were analyzed over 16 weeks from two separate phase 3, randomized, placebo-controlled, monotherapy trials (ADvocate1 and ADvocate2). Patient-reported outcomes were assessed using the following measures: Dermatology Life Quality Index (DLQI), EQ-5D-5L visual analogue scale (VAS), EQ-5D-5L index scores (UK and US), Patient-Reported Outcomes Measurement Information System (PROMIS) Anxiety, and PROMIS Depression. Results Treatment with lebrikizumab 250 mg every 2 weeks in two studies led to statistically significant improvements (based on nominal p values) versus placebo in DLQI since week 4 (the first timepoint assessed) for the following measures: change from baseline in DLQI total score (ADvocate1 − 7.8 vs − 2.8; ADvocate2 − 7.3 vs − 3.9), proportion of patients with DLQI ≥ 4-point improvement (ADvocate1 69.5% vs 36.2%; ADvocate2 60.5% vs 42.6%), DLQI total score ≤ 5 (ADvocate1 36.7% vs 8.8%; ADvocate2 29.6% vs 10.8%), and DLQI (0, 1) (ADvocate1 12.3% vs 1.7%; ADvocate2 9.2% vs 1.7%). Improvements in DLQI measures, EQ-5D-5L index scores (UK and US), and EQ-5D-5L VAS were sustained through week 16. Additionally, lebrikizumab improved PROMIS Anxiety and PROMIS Depression scores, and improvements were higher in patients with at least a mild score (≥ 55) versus placebo for PROMIS Anxiety (ADvocate1 − 7.43 vs − 1.51; ADvocate2 − 4.95 vs − 0.82) and PROMIS Depression (ADvocate1 − 7.42 vs − 2.46; ADvocate2 − 4.28 vs − 2.00). Conclusions Treatment with monotherapy 250 mg lebrikizumab for 16 weeks provided clinically meaningful improvements in outcomes related to QoL and mental health for patients with moderate-to-severe AD. Lebrikizumab-treated patients reported improvements in DLQI as early as week 4, the first measure since baseline. Trial Registration ClinicalTrials.gov Registration NCT04146363 (ADvocate1) and NCT04178967 (ADvocate2).

Published
2024
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6. Transforming respiratory diseases management: a CMO-based hospital pharmaceutical care model

Author

Borja Zarate-Tamames, Noe Garin, Marta Calvin-Lamas, Sonia Jornet, Jose J. Martinez-Simon, Sara Garcia-Gil, Eva M. Garcia-Rebolledo, and Ramon Morillo-Verdugo

Subjects
pharmaceutical care, respiratory diseases, hospital pharmacy, innovation, behavior, adherence, Therapeutics. Pharmacology, RM1-950
Abstract

IntroductionRespiratory diseases encompass a diverse range of conditions that significantly impact global morbidity and mortality. While common diseases like asthma and COPD exhibit moderate symptoms, less prevalent conditions such as pulmonary hypertension and cystic fibrosis profoundly affect quality of life and mortality. The prevalence of these diseases has surged by approximately 40% over the past 3 decades. Despite advancements in pharmacotherapy, challenges in drug administration, adherence, and adverse effects persist. This study aimed to develop and perform an interim validation of a Capacity-Motivation-Opportunity (CMO) model tailored for respiratory outpatients to enhance pharmaceutical care, which is the direct, responsible provision of medication-related care for the purpose of achieving definite outcomes that improve a patient’s quality of life, and overall wellbeing.MethodologyThis cross-sectional, multicenter study was conducted from March 2022 to March 2023. It comprised four phases: 1) forming an expert panel of 15 hospital pharmacists, 2) selecting respiratory pathologies based on prevalence and severity, 3) developing the CMO model’s pillars, and 4) integrating and conducting an interim validation of the model. The Capacity pillar focused on patient stratification and personalized care; the Motivation pillar aligned therapeutic goals through motivational interviewing; and the Opportunity pillar promoted the use of information and communication technologies (ICTs) for telemedicine.ResultsThe model included eight respiratory diseases based on expert assessment. For the Capacity pillar, 22 variables were defined for patient stratification, leading to three priority levels for personalized pharmaceutical care. In a preliminary test involving 201 patients across six hospitals, the stratification tool effectively classified patients according to their needs. The Motivation pillar adapted motivational interviewing techniques to support patient adherence and behavior change. The Opportunity pillar established teleconsultation protocols and ICT tools to enhance patient monitoring and care coordination.ConclusionThe CMO model, tailored for respiratory patients, provides a comprehensive framework for improving pharmaceutical care. By focusing on patient-centered care, aligning therapeutic goals, and leveraging technology, this model addresses the multifaceted needs of individuals with respiratory conditions. Future studies are necessary to validate this model in other healthcare systems and ensure its broad applicability.

Published
2024
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7. Analysis of a Parallel and Distributed BPSO Algorithm for EEG Classification: Impact on Energy, Time and Accuracy

Author

Escobar, Juan José, López-Rodríguez, Jesús, García-Gil, Diego, Morcillo-Jiménez, Roberto, Prieto, Beatriz, Ortiz, Andrés, Kimovski, Dragi, Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Rojas, Ignacio, editor, Ortuño, Francisco, editor, Rojas, Fernando, editor, Herrera, Luis Javier, editor, and Valenzuela, Olga, editor

Published
2024
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8. Machine Learning Model to Classify Patients with Complicated and Uncomplicated Type 2 Diabetes Mellitus in the New Civil Hospital of Guadalajara 'Juan I. Menchaca'

Author

Medina-Pérez, Víctor Manuel, Zúñiga-Mondragón, Isaac, Cruz-Ramos, José Alfonso, Arellano-Arteaga, Kevin Javier, Rusanova, Iryna, García-Gil, Gerardo, López-Armas, Gabriela del Carmen, Magjarević, Ratko, Series Editor, Ładyżyński, Piotr, Associate Editor, Ibrahim, Fatimah, Associate Editor, Lackovic, Igor, Associate Editor, Rock, Emilio Sacristan, Associate Editor, Flores Cuautle, José de Jesús Agustín, editor, Benítez-Mata, Balam, editor, Salido-Ruiz, Ricardo Antonio, editor, Alonso-Silverio, Gustavo Adolfo, editor, Dorantes-Méndez, Guadalupe, editor, Zúñiga-Aguilar, Esmeralda, editor, Vélez-Pérez, Hugo A., editor, Hierro-Gutiérrez, Edgar Del, editor, and Mejía-Rodríguez, Aldo Rodrigo, editor

Published
2024
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9. Sex matters in the association between cardiovascular health and incident dementia: evidence from real world data

Author

Anna Ponjoan, Jordi Blanch, Ester Fages-Masmiquel, Ruth Martí-Lluch, Lia Alves-Cabratosa, María del Mar Garcia-Gil, Gina Domínguez-Armengol, Francesc Ribas-Aulinas, Lluís Zacarías-Pons, and Rafel Ramos

Subjects
Electronic health records, General practitioner, Primary health care, Family practice, Heart disease risk factors, Diabetes, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429
Abstract

Abstract Background Cardiovascular health has been associated with dementia onset, but little is known about the variation of such association by sex and age considering dementia subtypes. We assessed the role of sex and age in the association between cardiovascular risk and the onset of all-cause dementia, Alzheimer’s disease, and vascular dementia in people aged 50–74 years. Methods This is a retrospective cohort study covering 922.973 Catalans who attended the primary care services of the Catalan Health Institute (Spain). Data were obtained from the System for the Development of Research in Primary Care (SIDIAP database). Exposure was the cardiovascular risk (CVR) at baseline categorized into four levels of Framingham-REGICOR score (FRS): low (FRS

Published
2024
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12. Real-world outcomes in patients with malignancy and moderate-to-severe psoriasis treated with guselkumab

Author

Gracia Cazaña, Tamara, Riera Monroig, Josep, Izu, Rosa, Yanguas, Ignacio, Lorda Espés, Marta, Sánchez Salas, María Pilar, García Gil, Miguel Fernando, Navarro Bielsa, Alba, Aldea Manrique, Beatriz, Almenara Blasco, Manuel, García-Latasa de Araníbar, Francisco Javier, Fuentelsaz, Victoria, Morales Callaghan, Ana, and Ara-Martín, Mariano

Published
2024
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14. The Pharmacokinetics, Safety and Tolerability of Aclidinium Bromide 400 μg Administered by Inhalation as Single and Multiple (Twice Daily) Doses in Healthy Chinese Participants

Author

Li W, Daoud SZ, Trivedi R, Lukka PB, Jimenez E, Molins E, Stewart C, Bharali P, and Garcia-Gil E

Subjects
aclidinium bromide, bronchodilator, china, chronic obstructive pulmonary disease, pharmacokinetics, safety., Diseases of the respiratory system, RC705-779
Abstract

Weimin Li,1 Sami Z Daoud,2 Roopa Trivedi,3 Pradeep B Lukka,4 Eulalia Jimenez,5 Eduard Molins,5 Catherine Stewart,6 Pranob Bharali,3,7 Esther Garcia-Gil8 1Clinical Trial Center, West China Hospital of Sichuan University, Chengdu, Sichuan Province, People’s Republic of China; 2Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA; 3Late Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Durham, NC, USA; 4Clinical & Quantitative Pharmacology, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Gaithersburg, MD, USA; 5Clinical & Quantitative Pharmacology, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Barcelona, Spain; 6Statistics, Phastar, Chiswick, London, UK; 7BioPharmaceuticals R&D Late-Stage Development, AstraZeneca India Pvt Ltd., Bangalore, Karnataka, India; 8Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Barcelona, SpainCorrespondence: Sami Z Daoud, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, One MedImmune Way, Gaithersburg, MD, 20878, USA, Tel +1 302-598-8614, Email Sami.Daoud@astrazeneca.comPurpose: To date, aclidinium pharmacokinetic (PK) studies have focused on Caucasian populations, and no data are available for Chinese populations. We aimed to characterize the PK and safety profile of aclidinium and its metabolites (LAS34823 and LAS34850) following single and multiple (twice-daily; BID) dosing in healthy Chinese participants, and to compare PK data between Chinese and Caucasian populations.Materials and methods: In this Phase I, open-label study (NCT03276052), healthy participants from a single site in China received aclidinium bromide 400 μg via a dry powder inhaler. The Day 1 single dose was followed by a washout period of 96 hours. On Days 5 through 8, participants received BID doses.Results: Twenty healthy Chinese participants, aged 18– 45 years, were enrolled. Aclidinium absorption was rapid (median time to maximum concentration [tmax] 0.08 hours post-dose following single/multiple doses). LAS34823 had a similar median tmax of 0.08 hours, whereas LAS34850 tmax occurred later (median 2.50– 3.00 hours). Aclidinium, LAS34823, and LAS34850 concentrations declined in a bi-phasic manner; geometric mean half-life was 13.5 hours (single dosing) and 21.4 hours (multiple dosing), while steady state was generally achieved after 5 days’ continuous dosing. Area under the concentration–time curve during a dosage interval (AUCτ) metabolite to parent ratios for LAS34823 were 2.6 (Day 1) and 2.9 (Day 9), while LAS34850 had ratios of 136.0 and 94.8, respectively. Aclidinium accumulation occurred after 5 days of BID dosing (LS mean accumulation ratio for AUCτ Day 9/Day 1: 214.1% [90% CI, 176.5, 259.6]); LAS34823 accumulation was similar, while LAS34850 accumulation was lower. Between-participant exposure variability was moderate to high for aclidinium and LAS34823, and low for LAS34850.Conclusion: Single and multiple doses of aclidinium were well tolerated in healthy Chinese participants. The safety profile of and exposure to aclidinium was consistent with previous studies conducted in Caucasian populations.Keywords: aclidinium bromide, bronchodilator, China, chronic obstructive pulmonary disease, pharmacokinetics, safety

Published
2023

15. Shallow geothermal energy systems for district heating and cooling networks: Review and technological progression through case studies

Author

Figueira, João S., García Gil, Alejandro, Vieira, Ana, Michopoulos, Apostolos K., Boon, David P., Loveridge, Fleur, Cecinato, Francesco, Götzl, Gregor, Epting, Jannis, Zosseder, Kai, Bloemendal, Martin, Woods, Michael, Christodoulides, Paul, Vardon, Philip J., Borg, Simon Paul, Erbs Poulsen, Søren, and Andersen, Theis Raaschou

Published
2024
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23. Interplay between mTOR and Purine Metabolism Enzymes and Its Relevant Role in Cancer

Author

Simone Allegrini, Marcella Camici, Mercedes Garcia-Gil, Rossana Pesi, and Maria Grazia Tozzi

Subjects
mTOR, purine metabolism, cancer, purinosome, one-carbon metabolism, mitochondria, Biology (General), QH301-705.5, Chemistry, QD1-999
Abstract

Tumor cells reprogram their metabolism to meet the increased demand for nucleotides and other molecules necessary for growth and proliferation. In fact, cancer cells are characterized by an increased “de novo” synthesis of purine nucleotides. Therefore, it is not surprising that specific enzymes of purine metabolism are the targets of drugs as antineoplastic agents, and a better knowledge of the mechanisms underlying their regulation would be of great help in finding new therapeutic approaches. The mammalian target of the rapamycin (mTOR) signaling pathway, which is often activated in cancer cells, promotes anabolic processes and is a major regulator of cell growth and division. Among the numerous effects exerted by mTOR, noteworthy is its empowerment of the “de novo” synthesis of nucleotides, accomplished by supporting the formation of purinosomes, and by increasing the availability of necessary precursors, such as one-carbon formyl group, bicarbonate and 5-phosphoribosyl-1-pyrophosphate. In this review, we highlight the connection between purine and mitochondrial metabolism, and the bidirectional relation between mTOR signaling and purine synthesis pathways.

Published
2024
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27. Resumen ejecutivo del documento de consenso para la formación y el desarrollo de la ecografía clínica en Medicina Interna: recomendaciones desde el Grupo de Trabajo de Ecografía Clínica de la Sociedad Española de Medicina Interna (GTECO-SEMI)

Author

Tung-Chen, Y., García de Casasola Sánchez, G., García Rubio, S., Beltrán Romero, L., Bernabéu Wittel, M., Briongos Figuero, L.S., Canora Lebrato, J., García Gil, D., López Palmero, S., Luordo Tedesco, D., Martín Rico, P., Mateos González, M., Méndez Bailón, M., Porcel, J.M., Serralta, G., Torres Arrese, M., Oteiza Olaso, J., Varela García, P., and Torres Macho, J.

Published
2024
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28. Executive summary of the consensus document for the training and development of clinical ultrasound in Internal Medicine: Recommendations from the Clinical Ultrasound Working Group of the Spanish Society of Internal Medicine (GTECO-SEMI)

Author

Tung-Chen, Yale, García de Casasola Sánchez, Gonzalo, García Rubio, Samuel, Beltrán Romero, Luis, Bernabéu Wittel, Máximo, Briongos Figuero, Laisa Socorro, Canora Lebrato, Jesús, García Gil, Daniel, López Palmero, Serafín, Luordo Tedesco, Davide, Martín Rico, Patricia, Mateos González, María, Méndez Bailón, Manuel, Porcel, José M., Serralta, Gonzalo, Torres Arrese, Marta, Oteiza Olaso, Julio, Varela García, Pablo, and Torres Macho, Juan

Published
2024
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29. Impact of bread diet on intestinal dysbiosis and irritable bowel syndrome symptoms in quiescent ulcerative colitis: A pilot study.

Author

Aleix Lluansí, Marc Llirós, Robert Carreras-Torres, Anna Bahí, Montserrat Capdevila, Anna Feliu, Laura Vilà-Quintana, Núria Elias-Masiques, Emilio Cueva, Laia Peries, Leyanira Torrealba, Josep Oriol Miquel-Cusachs, Míriam Sàbat, David Busquets, Carmen López, Sílvia Delgado-Aros, Librado Jesús Garcia-Gil, Isidre Elias, and Xavier Aldeguer

Subjects
Medicine, Science
Abstract

Gut microbiota may be involved in the presence of irritable bowel syndrome (IBS)-like symptomatology in ulcerative colitis (UC) patients in remission. Bread is an important source of dietary fiber, and a potential prebiotic. To assess the effect of a bread baked using traditional elaboration, in comparison with using modern elaboration procedures, in changing the gut microbiota and relieving IBS-like symptoms in patients with quiescent ulcerative colitis. Thirty-one UC patients in remission with IBS-like symptoms were randomly assigned to a dietary intervention with 200 g/d of either treatment or control bread for 8 weeks. Clinical symptomatology was tested using questionnaires and inflammatory parameters. Changes in fecal microbiota composition were assessed by high-throughput sequencing of the 16S rRNA gene. A decrease in IBS-like symptomatology was observed after both the treatment and control bread interventions as reductions in IBS-Symptom Severity Score values (p-value < 0.001) and presence of abdominal pain (p-value < 0.001). The treatment bread suggestively reduced the Firmicutes/Bacteroidetes ratio (p-value = 0.058). In addition, the Firmicutes/Bacteroidetes ratio seemed to be associated with improving IBS-like symptoms as suggested by a slight decrease in patient without abdominal pain (p-value = 0.059). No statistically significant differential abundances were found at any taxonomic level. The intake of a bread baked using traditional elaboration decreased the Firmicutes/Bacteroidetes ratio, which seemed to be associated with improving IBS-like symptoms in quiescent ulcerative colitis patients. These findings suggest that the traditional bread elaboration has a potential prebiotic effect improving gut health (ClinicalTrials.gov ID number of study: NCT05656391).

Published
2024
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30. Smart Data driven Decision Trees Ensemble Methodology for Imbalanced Big Data

Author

García-Gil, Diego, García, Salvador, Xiong, Ning, and Herrera, Francisco

Subjects
Computer Science - Machine Learning, Computer Science - Distributed, Parallel, and Cluster Computing, Statistics - Machine Learning
Abstract

Differences in data size per class, also known as imbalanced data distribution, have become a common problem affecting data quality. Big Data scenarios pose a new challenge to traditional imbalanced classification algorithms, since they are not prepared to work with such amount of data. Split data strategies and lack of data in the minority class due to the use of MapReduce paradigm have posed new challenges for tackling the imbalance between classes in Big Data scenarios. Ensembles have shown to be able to successfully address imbalanced data problems. Smart Data refers to data of enough quality to achieve high performance models. The combination of ensembles and Smart Data, achieved through Big Data preprocessing, should be a great synergy. In this paper, we propose a novel Smart Data driven Decision Trees Ensemble methodology for addressing the imbalanced classification problem in Big Data domains, namely SD_DeTE methodology. This methodology is based on the learning of different decision trees using distributed quality data for the ensemble process. This quality data is achieved by fusing Random Discretization, Principal Components Analysis and clustering-based Random Oversampling for obtaining different Smart Data versions of the original data. Experiments carried out in 21 binary adapted datasets have shown that our methodology outperforms Random Forest.

Published
2020

31. Genomic surveillance reveals dynamic shifts in the connectivity of COVID-19 epidemics

Author

Matteson, Nathaniel L., Hassler, Gabriel W., Kurzban, Ezra, Schwab, Madison A., Perkins, Sarah A., Gangavarapu, Karthik, Levy, Joshua I., Parker, Edyth, Pride, David, Hakim, Abbas, De Hoff, Peter, Cheung, Willi, Castro-Martinez, Anelizze, Rivera, Andrea, Veder, Anthony, Rivera, Ariana, Wauer, Cassandra, Holmes, Jacqueline, Wilson, Jedediah, Ngo, Shayla N., Plascencia, Ashley, Lawrence, Elijah S., Smoot, Elizabeth W., Eisner, Emily R., Tsai, Rebecca, Chacón, Marisol, Baer, Nathan A., Seaver, Phoebe, Salido, Rodolfo A., Aigner, Stefan, Ngo, Toan T., Barber, Tom, Ostrander, Tyler, Fielding-Miller, Rebecca, Simmons, Elizabeth H., Zazueta, Oscar E., Serafin-Higuera, Idanya, Sanchez-Alavez, Manuel, Moreno-Camacho, Jose L., García-Gil, Abraham, Murphy Schafer, Ashleigh R., McDonald, Eric, Corrigan, Jeremy, Malone, John D., Stous, Sarah, Shah, Seema, Moshiri, Niema, Weiss, Alana, Anderson, Catelyn, Aceves, Christine M., Spencer, Emily G., Hufbauer, Emory C., Lee, Justin J., King, Alison J., Ramesh, Karthik S., Nguyen, Kelly N., Saucedo, Kieran, Robles-Sikisaka, Refugio, Fisch, Kathleen M., Gonias, Steven L., Birmingham, Amanda, McDonald, Daniel, Karthikeyan, Smruthi, Martin, Natasha K., Schooley, Robert T., Negrete, Agustin J., Reyna, Horacio J., Chavez, Jose R., Garcia, Maria L., Cornejo-Bravo, Jose M., Becker, David, Isaksson, Magnus, Washington, Nicole L., Lee, William, Garfein, Richard S., Luna-Ruiz Esparza, Marco A., Alcántar-Fernández, Jonathan, Henson, Benjamin, Jepsen, Kristen, Olivares-Flores, Beatriz, Barrera-Badillo, Gisela, Lopez-Martínez, Irma, Ramírez-González, José E., Flores-León, Rita, Kingsmore, Stephen F., Sanders, Alison, Pradenas, Allorah, White, Benjamin, Matthews, Gary, Hale, Matt, McLawhon, Ronald W., Reed, Sharon L., Winbush, Terri, McHardy, Ian H., Fielding, Russel A., Nicholson, Laura, Quigley, Michael M., Harding, Aaron, Mendoza, Art, Bakhtar, Omid, Browne, Sara H., Olivas Flores, Jocelyn, Rincon Rodríguez, Diana G., Gonzalez Ibarra, Martin, Robles Ibarra, Luis C., Arellano Vera, Betsy J., Gonzalez Garcia, Jonathan, Harvey-Vera, Alicia, Knight, Rob, Laurent, Louise C., Yeo, Gene W., Wertheim, Joel O., Ji, Xiang, Worobey, Michael, Suchard, Marc A., Andersen, Kristian G., Campos-Romero, Abraham, Wohl, Shirlee, and Zeller, Mark

Published
2023
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39. Theoretical Background

Author

García Gil, Alejandro, Garrido Schneider, Eduardo Antonio, Mejías Moreno, Miguel, Santamarta Cerezal, Juan Carlos, Santamarta Cerezal, Juan Carlos, Series Editor, García Gil, Alejandro, Garrido Schneider, Eduardo Antonio, and Mejías Moreno, Miguel

Published
2022
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40. Underground Thermal Regime

Author

García Gil, Alejandro, Garrido Schneider, Eduardo Antonio, Mejías Moreno, Miguel, Santamarta Cerezal, Juan Carlos, Santamarta Cerezal, Juan Carlos, Series Editor, García Gil, Alejandro, Garrido Schneider, Eduardo Antonio, and Mejías Moreno, Miguel

Published
2022
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41. Environmental Impacts

Author

García Gil, Alejandro, Garrido Schneider, Eduardo Antonio, Mejías Moreno, Miguel, Santamarta Cerezal, Juan Carlos, Santamarta Cerezal, Juan Carlos, Series Editor, García Gil, Alejandro, Garrido Schneider, Eduardo Antonio, and Mejías Moreno, Miguel

Published
2022
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42. Legal Framework for Regulation

Author

García Gil, Alejandro, Garrido Schneider, Eduardo Antonio, Mejías Moreno, Miguel, Santamarta Cerezal, Juan Carlos, Santamarta Cerezal, Juan Carlos, Series Editor, García Gil, Alejandro, Garrido Schneider, Eduardo Antonio, and Mejías Moreno, Miguel

Published
2022
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44. Obtaining Terrain Thermal Parameters

Author

García Gil, Alejandro, Garrido Schneider, Eduardo Antonio, Mejías Moreno, Miguel, Santamarta Cerezal, Juan Carlos, Santamarta Cerezal, Juan Carlos, Series Editor, García Gil, Alejandro, Garrido Schneider, Eduardo Antonio, and Mejías Moreno, Miguel

Published
2022
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45. Introduction

Author

García Gil, Alejandro, Garrido Schneider, Eduardo Antonio, Mejías Moreno, Miguel, Santamarta Cerezal, Juan Carlos, Santamarta Cerezal, Juan Carlos, Series Editor, García Gil, Alejandro, Garrido Schneider, Eduardo Antonio, and Mejías Moreno, Miguel

Published
2022
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47. Geothermal Heat Pump

Author

García Gil, Alejandro, Garrido Schneider, Eduardo Antonio, Mejías Moreno, Miguel, Santamarta Cerezal, Juan Carlos, Santamarta Cerezal, Juan Carlos, Series Editor, García Gil, Alejandro, Garrido Schneider, Eduardo Antonio, and Mejías Moreno, Miguel

Published
2022
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49. Geothermal Supply System for a Winery on a Volcanic Island (Lanzarote, Canary Islands)

Author

Santamarta, Juan C., Pacheco, Giovanni Lemes, Rodríguez-Martín, Jesica, del Cristo Expósito, Mª, García-Gil, Alejandro, Cruz-Pérez, Noelia, Pisello, Anna Laura, Editorial Board Member, Hawkes, Dean, Editorial Board Member, Bougdah, Hocine, Editorial Board Member, Rosso, Federica, Editorial Board Member, Abdalla, Hassan, Editorial Board Member, Boemi, Sofia-Natalia, Editorial Board Member, Mohareb, Nabil, Editorial Board Member, Mesbah Elkaffas, Saleh, Editorial Board Member, Bozonnet, Emmanuel, Editorial Board Member, Pignatta, Gloria, Editorial Board Member, Mahgoub, Yasser, Editorial Board Member, De Bonis, Luciano, Editorial Board Member, Kostopoulou, Stella, Editorial Board Member, Pradhan, Biswajeet, Editorial Board Member, Abdul Mannan, Md., Editorial Board Member, Alalouch, Chaham, Editorial Board Member, Gawad, Iman O., Editorial Board Member, Nayyar, Anand, Editorial Board Member, Amer, Mourad, Series Editor, Çiner, Attila, editor, Banerjee, Santanu, editor, Lucci, Federico, editor, Radwan, Ahmed E., editor, Shah, Afroz Ahmad, editor, Doronzo, Domenico M., editor, Hamimi, Zakaria, editor, and Bauer, Wilfried, editor

Published
2023
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50. Association between use of enhanced recovery after surgery protocols and postoperative complications after gastric surgery for cancer (POWER 4): a nationwide, prospective multicentre study

Author

Farré, Mercè Güell, Font, Roser Farré, del Gobbo, Rafael Diaz, Jimenez, Raquel Sánchez, Reche, Isabel Pérez, Calvo, Belen Gil, García, Jordi Llorca, Sánchez, Laura Carrasco, Llimargas, Cristina Prat, García-Sánchez, Ana María, Martínez-Ragüés, Gema, Gómez-Fernández, María, del-Castillo-Criado, Álvaro, Martínez-Díaz, Ruth, Alegría-Rebollo, Sara, Ferrerode-Paz, Javier, García-Pérez, Cristina, Marcos-Contreras, Sergio, Fernández-García, Diana, Torío-Marcos, Maeva, Fernández, Omar Abdellah, Parreño-Manchado, Felipe Carlos, Martín, María Ángeles, Tena-Guerrero, José María, Palma-González, Estefanía, Flores-Flores, Gustavo, Zugasti-Echarte, Orreaga, Pérez-Bergara, Elena, Hernández-García, Susana, Martín-Vizcaíno, Marta, Yoldi-Murillo, Francisco Javier, Valencia-Alzueta, Maider, Chaveli-Díaz, Carlos, Miranda-Murua, Coro, Yárnoz-Irazábal, Concepción, Botella-Martínez, Sonsoles, López-Pardo, Rafael, Torres-Montalvo, Marta, Pinilla-Pico, Isabel, del-Cojo-Peces, Enrique, del Pilar Rodríguez-Chaparro, María, Gómez-Ríos, Manuel Ángel, del-Río-Regueira, Sara, Mosquera-Rodríguez, Eva, Hernández-Beslmeisl, Jessica, Perozo-Medina, María Alejandra, Darias-Delbey, Beneharo, del Carmen Martín-Lorenzo, María, González-Fariña, Vanessa, Rodríguez-Domínguez, Montserrat, Fernández-de-la-Vega-Medina, Jaime, Berrotarán-Ayub, Pilar, Valín-Martínez, José, Concepción-Santana, Laura, Cruz-Zorio, Raúl, Betancort-Gutiérrez Rodríguez, Dolores, Gómez-Viana, Leticia, Figueiredo, Olalla, Rodríguez, Ariadna, González, Manuel, Iglesias, David, Domínguez-Carrera, José Manuel, Olmo, Jorgedo, Del-Río-Fernández, Sabela, Dos-Santos-Carregal, Laura, Rodríguez-Forja, María Jesús, Campaña-Figueira, Olga, Álvarez-Escudero, Julián, Lesquereux-Martínez, Lucía, Parada-González, Purificación, Montenegro-Romero, Ricardo, Bustamante-Montalvo, Manuel, García-Placín, Ana Rosa, Carpintero-Rama, Carmen, Brea-Bahamonde, Sergio, Torres-Alfonso, José Ramón, Barragán-Serrano, Cristina, Posada-González, María, Salcedo-Cabañas, Gabriel, Vor-wald-Wolfgang, Peter, Otero-Martínez, Isabel, Jove-Alborés, Patricia, López-Otero, Marta, Pardellas-Rivera, Hermelinda, Maruri-Chimeno, Ignacio, González-Fernández, Sonia, Sánchez-Santos, Raquel, Luna-Mendoza, Luis, Lloria-Pons, Enrique, Gramuntell-Marco, Francisco, Cánovas-de-Lucas, Raúl, Sancho-Moya, Cristina, Risco, Raquel, Fernández-Esmerats, Anna, Sanahuja-Blasco, Josep Martí, López-Baamonde, Manuel, Ubré, Marta, Martínez-Pallí, Graciela, Momblán, Dulce, Rivas-Gallardo, Nuria, Sánchez-Martín, Rubén, Moral, Pedro, Navarro, Rosalía, Santé, Luis, Almenta, Esther, Muñoz-Hernández, Henar, Rodríguez-Jiménez, Rita Pilar, Ruiz, Nuria, Peláez, María Teresa, Rojo, Juan José, Gordaliza, Carlota, Jezieniecki, Carlos, Jimenez-Viñas, Carlos, Brugiotti, Carlo, Onchalos-Lopez, Ulices, Llácer-Pérez, Manuel, Batalla, Astrid, Azparren, Gonzalo, Bastitta, Micaela, Cueva, Luisa, Felipe, Mar, Giné, Marta, Gómez, Ana M., India, Inmaculada, Piñol, Santiago, Gimeno-Campos, Maria José, Moreno-Gázquez, Aurora, Llorens-Herrerías, Julio, Del-Castillo-Rodrigo, Gema, Herrero-Bogajo, María Luz, De Miguel-Cabrera, María Isabel, España-Pamplona, José Miguel, Gellida-Vilarroig, María, Jordá-Sanz, Laura, Gil-Trujillo, Silvia, Calatayud-Gómez, Laura, Valencia-Echeverri, Juan David, Baladrón-González, Víctor, Gil-Rendo, Aurora, Sanchez-García, Susana, García-Santos, Esther, Benito, Carmen, Lisbona, Cristina, Benito, Pilar, Correa-Chacón, Olga Cecilia, Alcázar-Urrea, Alejandro, Fernández-López, Ana Belén, Betancourt-Bastidas, Ramiro, Navarro-García, Inmaculada, Romera-Barba, Elena, Mira-Jovells, Nuria, Estevez-Perez, Liz Karime, Saludes-Serra, Judit, Olona-Casas, Carles, Vadillo-Bargalló, Jordi, Jorba-Martín, Rosa, Mojarro, Irene, Lorente, Juan Victor, Longo-Guridi, Pablo, Quintero-Moreno, Ana Maria, Soriano-López, David, de la Peña Gómez-Dominguez, Maria, Prieto-Candau, Cecilia, Hernández-Castillo, Marisol, Jarana, Irene, García-Andreu, Francisco, González-González, Jose, Díaz-Lara, María Dolores, Añón-Iranzo, Elena, Aguiló-Lucia, Javier, Fernandez-Martin, Maria Teresa, Guerra, Yessica, Gimeno-Fernández, Pablo, Iglesias-Morales, Carla, Villalba, Ana María Ríos, Nespereira-García, Paula, Castro-Neira, María José, Ochoa-Díez, María, García-Orallo, Silvia, Mozo-Segurado, Maialen, Gutiérrez-Cabezas, Jose Manuel, Gonzalo-González, Ruben, García-Álvarez, Raquel, Ramiro-Ruíz, Álvaro, González-Cofrade, María, Carvajal-Revuelta, Estefanía, Bellido-López, Ana, Redondo-Cristóbal, Guillermo, Amoza-Pais, Sonia, Díaz-Vico, Tamara, Moreno-Gijón, María, Sanz-Navarro, Sandra, Sanz-Álvarez, Lourdes M, Turienzo-Santos, Estrella Olga, Rodicio-Miravalles, Jose Luis, Rizzo-Ramos, Amaya, Cuéllar-Martínez, Ana, Álvarez-Fernández, Rosa Ana, Fernández-Seijo, Carmen, Álvarez-Barrial, Amelia, Gónzalez-Ortea, Carmen, Fernández-Rodriguez, Silvia, García-González, Nerea, Varela-Rodriguez, Lorena, Berzal-Canga, Elena, García-Díaz-Negrete, Ángela, García-Sánchez, Helena, Saenz-Abos, Javier, Ayuso-Iñigo, Beatriz, Vega-Colón, María, Palacios-Córdoba, Ángela Catalina, Quel-Collado, María Teresa, Olvera-García, Mercedes, Martinez-Sánchez, Agustina, Serrano-Alvarez, Carmen, Ganuza-Martínez, Eunate, Maroño-Boedo, María Jesús, Sánchez-Campos, Alberto, Escontrela-Rodríguez, Blanca Anuncia, Martínez-Ruiz, Alberto, Errazti-Olartecoechea, Gaizka, Rodeño-Esteban, Iratxe, Moreno-Allende, Tamara, Gutierrez-Grijalba, Oihane, Katary-niuk-Di-Costanzo, Yanina, Alvarez-Abad, Irene, Sendino-Cañizares, Patricia, Mifsut-Porcel, Patricia, Sarriugarte-Lasarte, Aingeru, Guerra-Lerma, Mikel, Logroño-Ejea, Margarita, Iturricastillo-Pérez, María Del Carmen, Gastaca-Abasolo, María, Muñoz-Sanz, María José, Iriarte-Zaranton, Ibai, Olea-De-La-Fuente, Erika, Mendiguren-Murua, Ana, Reka-Mediavilla, Lorena, Gastón-Moreno, Alberto, Martínez-De-Aragón-Remirez-De-Esparza, Gabriel Jesús, Sierra-Esteban, Valentín, Montero-Mejías, Gema, Pardo-Martínez, Claudia, Valadés-Periañez, Teresa, Marín-Moreno, Ana, Caro-González, Juan Ricardo, Rodríguez-Pérez, María José, Herrero-Herrero, José Carlos, Renedo-Corcóstegui, Pablo, Martín-Oliva, Alejandro, Fernández-Herrero, Ana Isabel, Andrieu-Estefanía, Nerea, Albaladejo-Magdalena, Javier, Álvarez-Rodriguez, María, Sosa-Rodríguez, Valentina, Fresnedo-Pérez, Raquel María, Gil-Lapetra, Cristina, Bolzoni-Marciel, Beatriz, Herrera-López, Maria Isabel, Setién-Moreno, Fernando, Castro-Costoya, Ana Zulema, Olarra-Nuel, José, De-Vega-Irañeta, Marta, Ugarte-Sierra, Bakarne, Vicente-Rodríguez, Irune, Fernández-Pablos, Francisco Javier, Abad-Alonso, Rafael Alberto, Maniega-Alba, Roberto, Ibáñez-Aguirre, Francisco Javier, Postigo-Morales, Susana, Intxaurraga-Fernández, Karmelo, Telletxea-Benguria, Sorkunde, Outón-Guerrero, Ángela, Acosta-Mérida, María Asunción, de la Plaza-Llamas, Roberto, García-Gil, José Manuel, Gemio-del-Rey, Ignacio Antonio, Cabellos-Olivares, Mercedes, Fernández-García, Raquel, Freitas, Lidia Castro, Alcorta, Beatriz Nacarino, Ayuso, María Martín, González, María Moral, Teruel, David García, Serrat-Puyol, Jordi, Molinas-Bruguera, Joan, Fernández, Sara, Peris-Tomás, Nuria, Díez-Ares, Jose Ángel, Periáñez-Gómez, Dolores, Gonzálvez-Guardiola, Paula, Trullenque-Juan, Ramón, Martínez-Mas, Ezequiel, Martínez, Estefanía, Martín, Julia, Higueras, Raquel, Cuenca, Sara, Martín-Vaquerizo, Beatriz, Espinosa-Moreno, Alma M., Sánchez-Merchante, Miriam, Alcañiz-Sobrino, Rebeca, Egea-Hita, Guillermo, García-del-Valle-y-Manzano, Santiago, Moreno-Blanco, Virginia, Bruna-Esteban, Marcos, Mingol-Navarro, Fernando, Vaqué-Urbaneja, Javier, Díaz-Cambronero, Óscar, Luján-Sandemetrio, Beatriz, Copariate-Piqueras, Bisila, Giménez-Salcedo, Sonia, Ripolles-Melchor, Javier, Abad-Motos, Ane, Abad-Gurumeta, Alfredo, Aracil-Escoda, Norma, Saez-Ruiz, Elena, Salva-chua-Fernandez, Rut, Paseiro-Crespo, Gloria, García-Nebreda, María, Toribio, Begoña, Ferrero-Celemin, Esther, García-Sancho-Téllez, Luis, Sánchez-López, José Daniel, Núñez O'Sullivan, Sara, Gar-cía-Virosta, Mariana, Rodriguez-Haro, Carmen, Hernández-O’Reilly, María, Suarez-de-la-Rica, Alejandro, Lopez-Martinez, Mercedes, Croes, Bryant, Mujica, Jaime, Maseda, Emilio, Alday-Muñoz, Enrique, Mata-Mena, Esperanza, García-Sanz, Iñigo, Marín, Cristina, Muñoz, Antonio Pedraza, Dominguez, Jorge Puertas, González-López, Rocío, Navarro-Quirós, Gisela, Pérez-Moreiras, M. Isabel, Conde-Rodriguez, María, Muinelo-Lorenzo, Manuel, Díez-Zapirain, Miren Jasone, Tejón-Pérez, Guillermo, Álvarez-Cebrián, María Asunción, Barrero-Ruiz, Eva, Capa-Fuertes, Eva, Carrillo-Rivas, Mariana, Hernandez-Sanchez, Isabel, Monteagudo-Cimiano, Valvanuz, Pascual-Casado, Ángela, Rábago-Morillón, Jose Luis, Martinez-Ubieto, Javier, Pascual-Bellosta, Ana, Ortega-Lucea, Sonia, Perez-Otal, Berta, Tardos-Ascaso, Lucia, Ligorred-Padilla, Luis Antonio, Tur-Martínez, Jaume, Rodríguez-Santiago, Joaquin, Pérez-Romero, Noelia, Puértolas-Rico, Noelia, Hernández-Giménez, Laura, Concepción-Martín, Vanessa, Molnar, Viktoria, Barbero, Macarena, San-Antonio, Belén, Pueyo, Alberto, Mayo-Ossorio, M de los Angeles, Bengoechea-Trujillo, Ander, Pacheco-Garcia, José Manuel, Diez-Remesal, Yolanda, Gonzalo-Millán, Alba, Berruezo-Camacho, Alberto, Alaez-Cortés, Azucena, Ortolá-Rocher, Begoña, Iglesias-Gallego, Berta, Martín-Montero, Eduardo, Arias-Cuesta, Gerardo, de la Hoz-Polo, Inés, Recuero-Torrijos, Isabel, Pereira-Torres, Lucia, Cañamas-Catalá, Maria, Martin-González, Maria C., Zambrana-García, Paloma, Llorente-Damas, Sergio, Aldecoa, Cesar, Perez-Gonzalez, Alba, Bolaño-Perez, Clara, Velasco-Andres, Delia, Aguado-Saster, Esther, Arranz, Irene, Mendez-Torrubiano, Itziar, Vaquero-Perez, Laura, Sanz-de-Leon, Maria Jesus, Rodicio, Pablo, Martin-Alfonso, Silvia, Martin-Tappi, David, Madrid-Tribano, Mario, Rioja-Garrido, Rocio, Morales-Jaquete, Borja, Vicente-Orgaz, Marta, Orozco-Vinasco, Adriana Carolina, Fraga-Casais, Gema, Miyagi-Yonamine, Any Minerva, Ramos-de-Castro, Raquel, Mejía-Arnaud, Rossel Alina, Saz-Castro, Rubén, Díaz-Peña, Patricia, Camps-Cervantes, Angels, Tormos-Perez, M Pilar, Galan-Menendez, Patricia, Esclapez-Sampere, Elena, Villarino-Villa, Laura, Loaiza-Aldeán, Yuri, Chocron-Dapratt, Ivette, Martinez-Silva, Olga, Matarin-Olmo, Silvia, Berges-Gutiérrez, Héctor, Pérez-Serrano, Macarena, Diaz-Castillo, Juan Javier, Sancho-Muñoz-de-Verger, Álvaro, Villanueva-Mena-Bernal, Jesús Alejandro, Gil-Gómez, Maria Lucia, Fernanz-Anton, Jesús, Marmaña-Mezquita, Sandra, Galofré-Pujol, Gonzalo, Jericó, Carlos, Motos-Micó, José Jacob, Orts-Micó, Francisco José, Serra-Díaz, Carlos, Arlandis-Félix, Francisco, Pérez-Climent, Nieves, Blanes-Pastor, Lorena, Jover-Pinillos, Jose Luis, Salvaterra, David, Linero, Manuel, Galipienzo, Javier, Alonso, Óscar, Ortega, Gloria, Gonzalez, Santiago, Lopez-Rojo, Irene, Ripollés-Melchor, Javier, Abdel-lah Fernández, Omar, Tormos-Pérez, María P., A Mayo-Ossorio, María, Gil-Gómez, Lucia, Parreño-Manchado, Felipe C, De-Miguel-Cabrera, María I, García-Erce, José A., Río-Fernández, Sabela del, Herrero-Bogajo, María L., Zorrilla-Vaca, Andrés, Vaquero-Pérez, Laura, Fernández-Martín, María T., Ferrando-Ortolà, Carlos, Ramírez-Rodríguez, José M., and Aldecoa, César

Published
2023
Full Text
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