103 results on '"Garcia-Saenz, Jose A"'
Search Results
2. Evaluation of European-based polygenic risk score for breast cancer in Ashkenazi Jewish women in Israel
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Levi, Hagai, Carmi, Shai, Rosset, Saharon, Yerushalmi, Rinat, Zick, Aviad, Yablonski-Peretz, Tamar, Consortium, The BCAC, Wang, Qin, Bolla, Manjeet K, Dennis, Joe, Michailidou, Kyriaki, Lush, Michael, Ahearn, Thomas, Andrulis, Irene L, Anton-Culver, Hoda, Antoniou, Antonis C, Arndt, Volker, Augustinsson, Annelie, Auvinen, Päivi, Freeman, Laura Beane, Beckmann, Matthias, Behrens, Sabine, Bermisheva, Marina, Bodelon, Clara, Bogdanova, Natalia V, Bojesen, Stig E, Brenner, Hermann, Byers, Helen, Camp, Nicola, Castelao, Jose, Chang-Claude, Jenny, Chirlaque, María-Dolores, Chung, Wendy, Clarke, Christine, Collaborators, NBCS, Collee, Margriet J, Colonna, Sarah, Consortium, CTS, Couch, Fergus, Cox, Angela, Cross, Simon S, Czene, Kamila, Daly, Mary, Devilee, Peter, Dork, Thilo, Dossus, Laure, Eccles, Diana M, Eliassen, A Heather, Eriksson, Mikael, Evans, Gareth, Fasching, Peter, Fletcher, Olivia, Flyger, Henrik, Fritschi, Lin, Gabrielson, Marike, Gago-Dominguez, Manuela, García-Closas, Montserrat, Garcia-Saenz, Jose Angel, Genkinger, Jeanine, Giles, Graham G, Goldberg, Mark, Guénel, Pascal, Hall, Per, Hamann, Ute, He, Wei, Hillemanns, Peter, Hollestelle, Antoinette, Hoppe, Reiner, Hopper, John, Investigators, ABCTB, Jakovchevska, Simona, Jakubowska, Anna, Jernström, Helena, John, Esther, Johnson, Nichola, Jones, Michael, Vijai, Joseph, Kaaks, Rudolf, Khusnutdinova, Elza, Kitahara, Cari, Koutros, Stella, Kristensen, Vessela, Kurian, Allison W, Lacey, James, Lambrechts, Diether, Le Marchand, Loic, Lejbkowicz, Flavio, Lindblom, Annika, Loibl, Sibylle, Lori, Adriana, Lubinski, Jan, Mannermaa, Arto, Manoochehri, Mehdi, Mavroudis, Dimitrios, Menon, Usha, Mulligan, AnnaMarie, Murphy, Rachel, Nevelsteen, Ines, Newman, William G, and Obi, Nadia
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Biological Sciences ,Biomedical and Clinical Sciences ,Genetics ,Oncology and Carcinogenesis ,Breast Cancer ,Prevention ,Cancer ,Humans ,Female ,Breast Neoplasms ,Genome-Wide Association Study ,Jews ,Israel ,Genetic Predisposition to Disease ,Risk Factors ,Multifactorial Inheritance ,Transcription Factors ,Genomics ,Polymorphism ,Genetic ,BCAC Consortium ,NBCS Collaborators ,CTS Consortium ,ABCTB Investigators ,Polymorphism ,Genetic ,Medical and Health Sciences ,Genetics & Heredity ,Clinical sciences - Abstract
BackgroundPolygenic risk score (PRS), calculated based on genome-wide association studies (GWASs), can improve breast cancer (BC) risk assessment. To date, most BC GWASs have been performed in individuals of European (EUR) ancestry, and the generalisation of EUR-based PRS to other populations is a major challenge. In this study, we examined the performance of EUR-based BC PRS models in Ashkenazi Jewish (AJ) women.MethodsWe generated PRSs based on data on EUR women from the Breast Cancer Association Consortium (BCAC). We tested the performance of the PRSs in a cohort of 2161 AJ women from Israel (1437 cases and 724 controls) from BCAC (BCAC cohort from Israel (BCAC-IL)). In addition, we tested the performance of these EUR-based BC PRSs, as well as the established 313-SNP EUR BC PRS, in an independent cohort of 181 AJ women from Hadassah Medical Center (HMC) in Israel.ResultsIn the BCAC-IL cohort, the highest OR per 1 SD was 1.56 (±0.09). The OR for AJ women at the top 10% of the PRS distribution compared with the middle quintile was 2.10 (±0.24). In the HMC cohort, the OR per 1 SD of the EUR-based PRS that performed best in the BCAC-IL cohort was 1.58±0.27. The OR per 1 SD of the commonly used 313-SNP BC PRS was 1.64 (±0.28).ConclusionsExtant EUR GWAS data can be used for generating PRSs that identify AJ women with markedly elevated risk of BC and therefore hold promise for improving BC risk assessment in AJ women.
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- 2023
3. SEOM–GEICAM–SOLTI clinical guidelines in advanced breast cancer (2022)
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Garcia-Saenz, Jose Angel, Blancas, Isabel, Echavarria, Isabel, Hinojo, Carmen, Margeli, Mireia, Moreno, Fernando, Pernas, Sonia, Ramon y Cajal, Teresa, Ribelles, Nuria, and Bellet, Meritxell
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- 2023
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4. Olaparib plus trastuzumab in HER2-positive advanced breast cancer patients with germline BRCA1/2 mutations: The OPHELIA phase 2 study
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Alés-Martínez, José Enrique, Balmaña, Judith, Sánchez-Rovira, Pedro, Salvador Bofill, Francisco Javier, García Sáenz, Jose Ángel, Pimentel, Isabel, Morales, Serafín, Fernández-Abad, María, Lahuerta Martínez, Ainhara, Ferrer, Neus, Zamora, Pilar, Bermejo, Begoña, Díaz-Redondo, Tamara, López-Ceballos, María Helena, Galán, María, Pérez-Escuredo, Jhudit, Calabuig, Laura, Sampayo, Miguel, Pérez-Garcia, José Manuel, Cortés, Javier, and Llombart-Cussac, Antonio
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- 2024
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5. Patient-reported outcomes in high-risk HR+ /HER2- early breast cancer patients treated with endocrine therapy with or without palbociclib within the randomized PENELOPEB study
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García-Sáenz, José Angel, Marmé, Frederik, Untch, Michael, Bonnefoi, Hervé, Kim, Sung-Bae, Bear, Harry, Mc Carthy, Nicole, Gelmon, Karen, Martin, Miguel, Kelly, Catherine M., Reimer, Toralf, Toi, Masakazu, Law, Ernest, Bhattacharyya, Helen, Gnant, Michael, Makris, Andreas, Seiler, Sabine, Burchardi, Nicole, Nekljudova, Valentina, Loibl, Sibylle, and Rugo, Hope S.
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- 2024
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6. In Reply
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Rugo, Hope S, Huober, Jens, Garcia-Saenz, Jose A, Masuda, Norikazu, Sohn, Joo Hyuk, Andre, Valerie AM, Barriga, Susana, Cox, Joanne, and Goetz, Matthew
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Biomedical and Clinical Sciences ,Oncology and Carcinogenesis ,Good Health and Well Being ,Oncology & Carcinogenesis ,Oncology and carcinogenesis - Abstract
This letter to the editor responds to Badoui et al. regarding data on abemaciclib dosages and adverse events.
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- 2021
7. Serial Analysis of Circulating Tumor Cells in Metastatic Breast Cancer Receiving First-Line Chemotherapy
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Magbanua, Mark Jesus M, Hendrix, Laura H, Hyslop, Terry, Barry, William T, Winer, Eric P, Hudis, Clifford, Toppmeyer, Deborah, Carey, Lisa Anne, Partridge, Ann H, Pierga, Jean-Yves, Fehm, Tanja, Vidal-Martínez, José, Mavroudis, Dimitrios, Garcia-Saenz, Jose A, Stebbing, Justin, Gazzaniga, Paola, Manso, Luis, Zamarchi, Rita, Antelo, María Luisa, De Mattos-Arruda, Leticia, Generali, Daniele, Caldas, Carlos, Munzone, Elisabetta, Dirix, Luc, Delson, Amy L, Burstein, Harold J, Qadir, Misbah, Ma, Cynthia, Scott, Janet H, Bidard, François-Clément, Park, John W, and Rugo, Hope S
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Cancer ,Prevention ,Breast Cancer ,Clinical Research ,Breast Neoplasms ,Female ,Humans ,Neoplastic Cells ,Circulating ,Prognosis ,Progression-Free Survival ,Proportional Hazards Models ,Reproducibility of Results ,Retrospective Studies ,Treatment Outcome ,Oncology and Carcinogenesis ,Oncology & Carcinogenesis - Abstract
BackgroundWe examined the prognostic significance of circulating tumor cell (CTC) dynamics during treatment in metastatic breast cancer (MBC) patients receiving first-line chemotherapy.MethodsSerial CTC data from 469 patients (2202 samples) were used to build a novel latent mixture model to identify groups with similar CTC trajectory (tCTC) patterns during the course of treatment. Cox regression was used to estimate hazard ratios for progression-free survival (PFS) and overall survival (OS) in groups based on baseline CTCs, combined CTC status at baseline to the end of cycle 1, and tCTC. Akaike information criterion was used to select the model that best predicted PFS and OS.ResultsLatent mixture modeling revealed 4 distinct tCTC patterns: undetectable CTCs (56.9% ), low (23.7%), intermediate (14.5%), or high (4.9%). Patients with low, intermediate, and high tCTC patterns had statistically significant inferior PFS and OS compared with those with undetectable CTCs (P < .001). Akaike Information Criterion indicated that the tCTC model best predicted PFS and OS compared with baseline CTCs and combined CTC status at baseline to the end of cycle 1 models. Validation studies in an independent cohort of 1856 MBC patients confirmed these findings. Further validation using only a single pretreatment CTC measurement confirmed prognostic performance of the tCTC model.ConclusionsWe identified 4 novel prognostic groups in MBC based on similarities in tCTC patterns during chemotherapy. Prognostic groups included patients with very poor outcome (intermediate + high CTCs, 19.4%) who could benefit from more effective treatment. Our novel prognostic classification approach may be used for fine-tuning of CTC-based risk stratification strategies to guide future prospective clinical trials in MBC.
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- 2021
8. Radiotherapy to regional nodes in early breast cancer: an individual patient data meta-analysis of 14 324 women in 16 trials
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Taylor, Carolyn, Dodwell, David, McGale, Paul, Hills, Robert K, Berry, Richard, Bradley, Rosie, Braybrooke, Jeremy, Clarke, Mike, Gray, Richard, Holt, Francesca, Liu, Zulian, Pan, Hongchao, Peto, Richard, Straiton, Ewan, Coles, Charlotte, Duane, Fran, Hennequin, Christophe, Jones, Glenn, Kühn, Thorsten, Oliveros, Sileida, Overgaard, Jens, Pritchard, Kathy I, Suh, Chang-Ok, Beake, Graham, Boddington, Clare, Davies, Christina, Davies, Lucy, Evans, Vaughan, Gay, Jo, Gettins, Lucy, Godwin, Jon, James, Sam, Kerr, Amanda, Liu, Hui, MacKinnon, Elizabeth, Mannu, Gurdeep, McHugh, Theresa, Morris, Philip, Nakahara, Mariko, Read, Simon, Taylor, Hannah, Ferguson, John, Scheurlen, Hans, Zurrida, Stefano, Galimberti, Viviana, Ingle, James, Valagussa, Pinuccia, Veronesi, Umberto, Anderson, Stewart, Tang, Gong, Fisher, Bernard, Fossa, Sophie, Valborg Reinertsen, Kristin, Host, Herman, Muss, Hyman, Holli, Kaija, Albain, Kathy, Arriagada, Rodrigo, Bartlett, John, Bergsten-Nordström, Elizabeth, Bliss, Judith, Brain, Etienne, Carey, Lisa, Coleman, Robert, Cuzick, Jack, Davidson, Nancy, Del Mastro, Lucia, Di Leo, Angelo, Dignam, James, Dowsett, Mitch, Ejlertsen, Bent, Francis, Prue, García-Sáenz, José Angel, Gelber, Rich, Gnant, Michael, Goetz, Matthew, Goodwin, Pam, Halpin-Murphy, Pat, Hayes, Dan, Hill, Catherine, Jagsi, Reshma, Janni, Wolfgang, Loibl, Sibylle, Mamounas, Eleftherios, Martín, Miguel, McIntosh, Stuart, Mukai, Hirofumi, Nekljudova, Valentina, Norton, Larry, Ohashi, Yasuo, Piccart, Martine, Pierce, Lori, Raina, Vinod, Rea, Daniel, Regan, Meredith, Robertson, John, Rutgers, Emiel, Salgado, Roberto, Slamon, Dennis, Spanic, Tanja, Sparano, Joseph, Steger, Guenther, Toi, Masakazu, Tutt, Andrew, Viale, Giuseppe, Wang, Xiang, Wilcken, Nicholas, Wolmark, Norman, Yu, Ke-Da, Cameron, David, Bergh, Jonas, Swain, Sandra, Whelan, Tim, and Poortmans, Philip
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- 2023
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9. Imlunestrant, an oral selective estrogen receptor degrader (SERD), as monotherapy and in combination with abemaciclib, in endometrioid endometrial cancer (EEC): Results from the EMBER phase 1a/1b study.
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Yonemori, Kan, primary, Banda, Kalyan, additional, Boni, Valentina, additional, Sohn, Joohyuk, additional, Meniawy, Tarek, additional, Lombard, Janine Margaret, additional, Kaufman, Peter A., additional, Richardson, Debra L., additional, Bender Somme, Laura, additional, Matsumoto, Koji, additional, Giridhar, Karthik, additional, Garcia Saenz, Jose Angel, additional, Prenen, Hans, additional, Doger de Spéville Uribe, Bernard, additional, Dizon, Don S., additional, García-Corbacho, Javier, additional, Li, Yujia, additional, Nguyen, Bastien, additional, Ismail-Khan, Roohi, additional, and Neven, Patrick, additional
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- 2024
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10. Correction to: SEOM–GEICAM–SOLTI clinical guidelines in advanced breast cancer (2022)
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Garcia-Saenz, Jose Angel, Blancas, Isabel, Echavarria, Isabel, Hinojo, Carmen, Margeli, Mireia, Moreno, Fernando, Pernas, Sonia, Ramon y Cajal, Teresa, Ribelles, Nuria, and Bellet, Meritxell
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- 2023
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11. Incorporating progesterone receptor expression into the PREDICT breast prognostic model
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Grootes, Isabelle, Keeman, Renske, Blows, Fiona M., Milne, Roger L., Giles, Graham G., Swerdlow, Anthony J., Fasching, Peter A., Abubakar, Mustapha, Andrulis, Irene L., Anton-Culver, Hoda, Beckmann, Matthias W., Blomqvist, Carl, Bojesen, Stig E., Bolla, Manjeet K., Bonanni, Bernardo, Briceno, Ignacio, Burwinkel, Barbara, Camp, Nicola J., Castelao, Jose E., Choi, Ji-Yeob, Clarke, Christine L., Couch, Fergus J., Cox, Angela, Cross, Simon S., Czene, Kamila, Devilee, Peter, Dörk, Thilo, Dunning, Alison M., Dwek, Miriam, Easton, Douglas F., Eccles, Diana M., Eriksson, Mikael, Ernst, Kristina, Evans, D. Gareth, Figueroa, Jonine D., Fink, Visnja, Floris, Giuseppe, Fox, Stephen, Gabrielson, Marike, Gago-Dominguez, Manuela, García-Sáenz, José A., González-Neira, Anna, Haeberle, Lothar, Haiman, Christopher A., Hall, Per, Hamann, Ute, Harkness, Elaine F., Hartman, Mikael, Hein, Alexander, Hooning, Maartje J., Hou, Ming-Feng, Howell, Sacha J., Ito, Hidemi, Jakubowska, Anna, Janni, Wolfgang, John, Esther M., Jung, Audrey, Kang, Daehee, Kristensen, Vessela N., Kwong, Ava, Lambrechts, Diether, Li, Jingmei, Lubiński, Jan, Manoochehri, Mehdi, Margolin, Sara, Matsuo, Keitaro, Taib, Nur Aishah Mohd, Mulligan, Anna Marie, Nevanlinna, Heli, Newman, William G., Offit, Kenneth, Osorio, Ana, Park, Sue K., Park-Simon, Tjoung-Won, Patel, Alpa V., Presneau, Nadege, Pylkäs, Katri, Rack, Brigitte, Radice, Paolo, Rennert, Gad, Romero, Atocha, Saloustros, Emmanouil, Sawyer, Elinor J., Schneeweiss, Andreas, Schochter, Fabienne, Schoemaker, Minouk J., Shen, Chen-Yang, Shibli, Rana, Sinn, Peter, Tapper, William J., Tawfiq, Essa, Teo, Soo Hwang, Teras, Lauren R., Torres, Diana, Vachon, Celine M., van Deurzen, Carolien H.M., Wendt, Camilla, Williams, Justin A., Winqvist, Robert, Elwood, Mark, Schmidt, Marjanka K., García-Closas, Montserrat, and Pharoah, Paul D.P.
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- 2022
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12. Breast Cancer Management During COVID-19 Pandemic in Madrid: Surgical Strategy
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Brenes Sánchez, Juana María, Picado, Amanda López, Olivares Crespo, María Eugenia, García Sáenz, José Ángel, De La Plata Merlo, Rosa María, and De La Muela, María Herrera
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- 2021
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13. Cross-sectional and longitudinal associations of adherence to WCRF/AICR cancer prevention recommendations with health-related quality of life in breast cancer survivors. Health-EpiGEICAM study
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Lope, Virginia, Guerrero-Zotano, Ángel, Fernández de Larrea-Baz, Nerea, Antolín, Silvia, Benavent Viñuales, Marta, Bermejo, Begoña, Ruiz-Moreno, Emma, Baena-Cañada, José Manuel, París, Lorena, Antón, Antonio, Chacón, José Ignacio, Muñoz, Montserrat, García-Sáenz, José Angel, Olier, Clara, Sánchez Rovira, Pedro, Arcusa Lanza, Angels, González, Sonia, Brunet, Joan, Oltra, Amparo, Bezares, Susana, Rosell, Libertad, Pérez-Gómez, Beatriz, Pastor-Barriuso, Roberto, Martín, Miguel, and Pollán, Marina
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- 2024
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14. The clinical use of circulating tumor cells (CTCs) enumeration for staging of metastatic breast cancer (MBC): International expert consensus paper
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Cristofanilli, Massimo, Pierga, Jean-Yves, Reuben, James, Rademaker, Alfred, Davis, Andrew A., Peeters, Dieter J., Fehm, Tanja, Nolé, Franco, Gisbert-Criado, Rafael, Mavroudis, Dimitrios, Grisanti, Salvatore, Giuliano, Mario, Garcia-Saenz, Jose A., Stebbing, Justin, Caldas, Carlos, Gazzaniga, Paola, Manso, Luis, Zamarchi, Rita, de Lascoiti, Angela Fernandez, De Mattos-Arruda, Leticia, Ignatiadis, Michail, Cabel, Luc, van Laere, Steven J., Meier-Stiegen, Franziska, Sandri, Maria-Teresa, Vidal-Martinez, Jose, Politaki, Eleni, Consoli, Francesca, Generali, Daniele, Cappelletti, Maria Rosa, Diaz-Rubio, Eduardo, Krell, Jonathan, Dawson, Sarah-Jane, Raimondi, Cristina, Rutten, Annemie, Janni, Wolfgang, Munzone, Elisabetta, Carañana, Vicente, Agelaki, Sofia, Almici, Camillo, Dirix, Luc, Solomayer, Erich-Franz, Zorzino, Laura, Darrigues, Lauren, Reis-Filho, Jorge S., Gerratana, Lorenzo, Michiels, Stefan, Bidard, François-Clément, and Pantel, Klaus
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- 2019
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15. Safety and tolerability of subcutaneous trastuzumab for the adjuvant treatment of human epidermal growth factor receptor 2-positive early breast cancer: SafeHer phase III study's primary analysis of 2573 patients
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Koroveshi, Dhurata, Bouzid, Kamel, Casalnuovo, Monica, Cascallar, Diana, Korbenfeld, Ernesto Pablo, Bastick, Patricia, Beith, Jane, Colosimo, Maree, Friedlander, Michael, Ganju, Vinod, Green, Michael, Patterson, Kevin, Redfern, Andrew, Richardson, Gary, Ceric, Timur, Gordana, Kecman, Beato, Carlos Augusto, Ferrari, Marcela, Hegg, Roberto, Helena, Vanessa, Ismael, Gustavo Fernando, Lessa, Alvaro Edson, Mano, Max, Morelle, Alessandra, Nogueira, Jose Alberto, Timcheva, Konstanta, Tomova, Antoaneta, Tsakova, Maya, Zlatareva-Petrova, Ani, Asselah, Jamil, Assi, Hazem, Brezden-Masley, Christine, Chia, Stephen, Freedman, Ori, Harb, Mohammed, Joy, Anil Abraham, Kulkarni, Swati, Prady, Catherine, Gaete, Alejandro Andres Acevedo, Matamala, Luis, Torres, Roberto, Yanez, Eduardo, Franco, Sandra, Urrego, Marcela, Gugić, Damir, Vrbanec, Damir, Melichar, Bohuslav, Prausová, Jana, Vyzula, Rostislav, Pilarte, Rafael Gutierrez, León, María Isabel, Muñoz, Rene, Ramos, Glenda, Azeem, Hamdy Abdel, Aziz, Amr Abdel, El Zawahry, Heba, Osegueda, Finlander Rosales, Alexandre, Jerome, Artignan, Xavier, Barletta, Hugues, Beguier, Emmanuel, Berdah, Jean-François, Marty, Chantal Bernard, Bollet, Marc, Bourgeois, Hugues, Bressac, Claude, Burki, Franck, Campone, Mario, Coeffic, David, Cojocarasu, Oana Zveltlana, Dagada, Corinne, Dalenc, Florence, Del Piano, Francesco, Desauw, Christophe, Desmoulins, Isabelle, Dohollou, Nadine, Egreteau, Joelle, Ferrero, Jean-Marc, Foa, Cyril, Garidi, Reda, Gasnault, Laurent, Gligorov, Joseph, Guardiola, Emmanuel, Hamizi, Salima, Jarcau, Rosana, Jacquin, Jean-Philippe, Jaubert, Dominique, Jolimoy, Geneviève, Mineur, Hortense Laharie, Largillier, Remy, Leduc, Bernard, Martin, Philippe, Melis, Adrien, Monge, Jeremy, Moullet, Isabelle, Mousseau, Mireille, Nguyen, Suzanne, Orfeuvre, Hubert, Petit, Thierry, Pivot, Xavier, Priou, Frank, Bach, Isabelle Sillet, Simon, Helene, Stefani, Laetitia, Uwer, Lionel, Youssef, Ali, Aktas, Bahriye, von der Assen, Albert, Augustin, Doris, Balser, Christina, Bauer, Lelia-Eveline, Bechtner, Christina, Beyer, Greta, Brucker, Cosima, Bückner, Ute, Busch, Steffi, Christensen, Bernd, Deryal, Mustafa, Farrokh, Andre, Faust, Elke, Friedrichs, Kay, Graf, Heiko, Griesshammer, Martin, Grischke, Eva-Maria, Hänle, Claudia, Heider, Andrea, Henschen, Stephan, Hesse, Tobias, Jackisch, Christian, Kisro, Jens, Köhler, Andreas, Kuemmel, Sherko, Lampe, Dieter, Lantzsch, Tilmann, Latos, Kunibert, Lex, Benno, Liedtke, Cornelia, Luedders, Doerte, Maintz, Christoph, Müller, Volkmar, Overkamp, Friedrich, Park-Simon, Tjoung-won, Paul, Marion, Prechtl, Anita, Ringsdorf, Uta, Runnebaum, Ingo, Ruth, Sylvia, Salat, Christoph, Scheffen, Iris, Schilling, Jörg, Schmatloch, Sabine, Schmidt, Marcus, Schneeweiss, Andreas, Schrader, Iris, Seipelt, Gernot, Simon, Elke, Stefek, Andrea, Stickeler, Elmar, Thill, Marc, Tio, Joke, Tuczek, Anna, Warm, Mathias, Weigel, Michael, Wischnik, Arthur, Wojcinski, Sebastian, Ziegler-Löhr, Katja, Aravantinos, Gerasimos, Ardavanis, Alexandros, Fountzilas, George, Gogas, Helen, Kakolyris, Stylianos, Mavroudis, Dimitris, Papadimitriou, Christos, Papandreou, Christos, Papazisis, Konstantinos, Castro, Hugo, Hernandez-Monroy, Cesar Estuardo, Ngan, Roger, Yeo, Winnie, Bittner, Nora, Boer, Katalin, Csejtei, Andras, Horvath, Zsolt, Kocsis, Judit, Mangel, László Csaba, Mezei, Klara, Nagy, Zsuzsanna, Szanto, Janos, Atmakusuma, Djumhana, Fadjari, Heri, Kurnianda, Djohan, Prayogo, Nugroho, Tanggo, Eddie Herman, Coate, Linda, Hennessy, Bryan, Kelly, Cathy, Martin, Michael, Nasim, Saira, O'Connor, Miriam, Aieta, Michele, Allegrini, Giacomo, Amadori, Dino, Bidoli, Paolo, Biti, Giampaolo, Bordonaro, Roberto, Bottini, Alberto, Carterni, Giacomo, Cavanna, Luigi, Cazzaniga, Marina, Cognetti, Francesco, Contu, Antonio, Cruciani, Giorgio, Donadio, Michela, Falcone, Alfredo, Farci, Daniele, Forcignanò, R. Chiara, Frassoldati, Antonio, Gaion, Fernando, Gamucci, Teresa, Giotta, Francesco, de Laurentiis, Michele, Livi, Lorenzo, Lorusso, Vito, Maiello, Evaristo, Marchetti, Paolo, Mariani, Gabriella, Mion, Marta, Moscetti, Luca, Musolino, Antonino, Pazzola, Antonio, Pedrazzoli, Paolo, Pigi, Andrea, de Placido, Sabino, Caremoli, Elena Rota, Santoro, Armando, Tienghi, Amelia, Ahn, Jin-Seok, Jung, Kyung Hae, Lee, Keun Seok, Lee, Soo Hyeon, Seo, Jae Hong, Sohn, Joo-Hyuk, Cesas, Alvydas, Juozaityte, Elona, Cheah, Nellie Lay Chin, Chong, Flora Li Tze, Devi, Beena C.R., Phua, Vincent, Teoh, Darren, Ching, Lee Wei, Yusof, Mastura, Corona, Jorge, Dominguez, Adriana, Mendoza, René Lazaro González, Hernandez, Carlos Alberto, Ramiro, Alejandro Juarez, Santos, Juan Matos, Espinosa, Paola Morales, Villarreal Garza, Cynthia Mayte, Errihani, Hassan, Bakker, Sandra, van den Berkmortel, Franchette, Blaisse, R.J.B., Huinink, Daan ten Bokkel, van den Bosch, J., Braun, J.J., Dercksen, M.W., Droogendijk, Helga, Erdkamp, Frans, Haringhuizen, Annebeth, de Jongh, F.E., Kok, T.C., Los, Maartje, Madretsma, Stanley, Terwogt, Jetske M. Meerum, van der Padt, Annemieke, van Rossum-Schornagel, Quirine Clementine, Smilde, T.J., de Valk, Bart, van der Velden, Annette, van Warmerdam, Laurence, van de Wouw, A.J., North, Richard, Kersten, Christian, Mjaaland, Ingvild, Wist, Erik, Aziz, Zeba, Masood, Nehal, Rashid, Kamran, Shah, Mazhar, Alcedo, Juan Carlos, Aleman, Diana, Neciosup, Silvia, Reategui, Rocio, Valdiviezo, Natalia, Vera, Luis, Fernando, Gracieux, Roque, Fernando, Strebel, Heinrik Martin, Krzemieniecki, Krzysztof, Litwiniuk, Maria, Mruk, Andrzej, Pienkowski, Tadeusz, Sawrycki, Piotr, Slomian, Grzegorz, Tomczak, Piotr, Afonso, Noemia, Cardoso, Fátima, Damasceno, Margarida, Nave, Monica, Badulescu, Florinel, Ciule, Larisa, Curescu, Stefan, Eniu, Alexandru, Filip, Dumitru, Grecea, Daniela, Jinga, Dan-Corneliu, Lungulescu, Dan, Oprean, Cristina Marinela, Stanculeanu, Dana Lucia, Turdean, Maria, Dvornichenko, Viktoria, Emelyanov, Sergey, Lichinitser, Mikhail, Manikhas, Alexey, Sakaeva, Dina, Shirinkin, Vadim, Stroyakovskiy, Daniil, Abulkhair, Omalkhair, Zekri, Jamal, Filipovic, Sladjana, Kovcin, Vladimir, Nedovic, Jasmina, Pesic, Jasna, Vasovic, Suzana, Ng, Raymond, Bystricky, Branislav, Leskova, Jaroslava, Mardiak, Jozef, Mišurová, Etela, Wagnerova, Maria, Takač, Iztok, Demetriou, Georgia Savva, Dreosti, Lydia, Govender, Poovandren, Jordaan, Johannes Petrus, Veersamy, Petrosian, Romero, Jose Luis Alonso, Lopez, Norberto Batista, Arias, Carmen Cañabate, Chacon, Jose, Aramburo, Antonio Fernandez, Morales, Luis Antonio Fernandez, Garcia, Mirta, Estevez, Laura Garcia, Garcia-Palomo Perez, Andres, Garcia Saenz, Jose Angel, Garcia Sanchis, Laura, Cubells, Laia Garrigos, Cortijo, Lucia Gonzalez, Santiago, Santiago Gonzalez, De Aranguiz, Blanca Hernando Fernandez, Mañas, José Juan Illarramendi, Gallego, Pedro Jimenez, Cussac, Antonio Llombart, Ferrandiz, Cristina Llorca, Garrido, Maria Lomas, Alvarez, Pilar Lopez, Vega, Jose Manuel Lopez, Del Prado, Purificacion Martinez, Jañez, Noelia Martinez, Murillo, Serafin Morales, Rosales, Adolfo Murias, Jaso, Laura Murillo, Fernandez, Ignacio Pelaez, Martorell, Antonia Perello, Carrion, Ramon Perez, Simon, Sonia Pernas, Alcibar, Arrate Plazaola, Lorenzo, Jose Ponce, Garcia, Vanesa Quiroga, Asensio, Teresa Ramon y Cajal, Maicas, Maria Dolores Torregrosa, Villanueva Silva, Maria Jose, Killander, Fredrika, Svensson, Jan Henry, Fehr, Mathias, Hauser, Nik, Müller, Andreas, Pagani, Olivia, Passmann-Kegel, Heike, Popescu, Razvan, Rabaglio, Manuela, Rauch, Daniel, Schlatter, Christina, Zaman, Khalil, Chang, Tsai-Wang, Huang, Chiun-Sheng, Wang, Hwei-Chung, Yu, Jyh-Cherng, Bandidwattanawong, Chanyoot, Maneechavakajorn, Jedzada, Seetalarom, Kasan, Dejthevaporn, Thitiya (Sirisinha), Somwangprasert, Areewan, Vongsaisuwon, Mawin, Akbulut, Hakan, Altundag, Kadri, Arican, Ali, Bozcuk, Hakan, Eralp, Yesim, Idris, Mohamed, Isikdogan, Abdurrahman, Senol, Coskun Hasan, Sevinc, Alper, Uygun, Kazim, Yucel, Eftal, Yucel, Idris, Yumuk, Fulden, Shparyk, Yaroslav, Voitko, Nataliia, Jaloudi, Mohammed, Adams, Jocelyn, Agrawal, Rajiv, Ahmed, Samreen, Alhasso, Abdulla, Allerton, Rozenn, Anwar, Suhail, Archer, Caroline, Ashford, Richard, Barraclough, Lisa, Bertelli, Gianfilippo, Bishop, Jill, Branson, Tony, Butt, Mohammed, Chakrabarti, Amit, Chakraborti, Prabir, Churn, Mark, Crowley, Clare, Davis, Ruth, Dhadda, Amandeep, Eldeeb, Hany, Fraser, Judith, Hall, Julia, Hickish, Tamas, Hogg, Martin, Howe, Theresa, Joffe, Jonathan, Kelleher, Muireann, Kelly, Stephen, Kendall, Anne, Kristeleit, Hartmut, Lumsden, Graeme, Macmillan, Craig, MacPherson, Iain, Malik, Zafar, Mithal, Natasha, Neal, Anthony, Panwar, Udaiveer, Proctor, Andrew, Proctor, Steven John, Raj, Sanjay, Rehman, Shazza, Sandri, Ines, Scatchard, Kate, Sherwin, Elizabeth, Sims, Eliot, Singer, Julian, Smith, Sarah, Tahir, Saad, Taylor, Wendy, Tsalic, Medy, Verrill, Mark, Wardley, Andrew, Waters, Simon, Wheatley, Duncan, Wright, Kathryn, Yuille, Frances, Alonso, Isabel, Artagaveytia, Nora, Rodriguez, Robinson, Arbona, Esther, Garcia, Yuraima, Lion, Lorena, Marcano, Dalila, Van Thuan, Tran, Gligorov, J., Ataseven, B., Verrill, M., De Laurentiis, M., Jung, K.H., Azim, H.A., Al-Sakaff, N., Lauer, S., Shing, M., and Pivot, X.
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- 2017
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16. Could the Addition of Cetuximab to Conventional Radiation Therapy Improve Organ Preservation in Those Patients With Locally Advanced Larynx Cancer Who Respond to Induction Chemotherapy? An Organ Preservation Spanish Head and Neck Cancer Cooperative Group Phase 2 Study
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Mesía, Ricard, Garcia-Saenz, Jose A., Lozano, Alicia, Pastor, Miguel, Grau, Juan J., Martínez-Trufero, Javier, Lambeaz, Julio, Martínez-Galán, Joaquina, Mel, Jose R., González, Belen, Vázquez, Silvia, Mañós, Manel, Taberna, Miren, Cirauqui, Beatriz, del Barco, Elvira, Casado, Esther, Rubió-Casadevall, Jordi, Rodríguez-Jaráiz, Angles, and Cruz, Juan J.
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- 2017
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17. Physical activity and breast cancer risk by pathological subtype
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Lope, Virginia, Martín, Miguel, Castelló, Adela, Casla, Soraya, Ruiz, Amparo, Baena-Cañada, Jose Manuel, Casas, Ana Mª, Calvo, Lourdes, Bermejo, Begoña, Muñoz, Montserrat, Ramos, Manuel, de Juan-Ferré, Ana, Jara, Carlos, Antón, Antonio, Jimeno, Mª Ángeles, Lluch, Ana, Antolín, Silvia, García-Sáenz, José Ángel, Estévez, Purificación, Arriola-Arellano, Esperanza, Gavilá, Joaquín, Pérez-Gómez, Beatriz, Carrasco, Eva, and Pollán, Marina
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- 2017
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18. A Phase 2 Open Label, Single-Arm Trial to Evaluate the Combination of Cetuximab Plus Taxotere, Cisplatin, and 5-Flurouracil as an Induction Regimen in Patients With Unresectable Squamous Cell Carcinoma of the Head and Neck
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Mesía, Ricard, Vázquez, Silvia, Grau, Juan J., García-Sáenz, Jose A., Lozano, Alicia, García, Carlos, Carles, Joan, Irigoyen, Antonio, Mañós, Manel, García-Paredes, Beatriz, del Barco, Elvira, Taberna, Miren, Escobar, Yolanda, and Cruz, Juan J.
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- 2016
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19. Treatment With Adjuvant Abemaciclib Plus Endocrine Therapy in Patients With High-risk Early Breast Cancer Who Received Neoadjuvant Chemotherapy
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Martin, Miguel, primary, Hegg, Roberto, additional, Kim, Sung-Bae, additional, Schenker, Michael, additional, Grecea, Daniela, additional, Garcia-Saenz, Jose Angel, additional, Papazisis, Konstantinos, additional, Ouyang, QuChang, additional, Lacko, Aleksandra, additional, Oksuzoglu, Berna, additional, Reeves, James, additional, Okera, Meena, additional, Testa, Laura, additional, Shimizu, Chikako, additional, Denduluri, Neelima, additional, Adamchuk, Hryhoriy, additional, Dakhil, Shaker, additional, Wei, Ran, additional, Forrester, Tammy, additional, Fernandez, Maria Munoz, additional, Zimmermann, Annamaria, additional, Headley, Desiree, additional, and Johnston, Stephen R. D., additional
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- 2022
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20. Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data
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Bidard, François-Clément, Peeters, Dieter J, Fehm, Tanja, Nolé, Franco, Gisbert-Criado, Rafael, Mavroudis, Dimitrios, Grisanti, Salvatore, Generali, Daniele, Garcia-Saenz, Jose A, Stebbing, Justin, Caldas, Carlos, Gazzaniga, Paola, Manso, Luis, Zamarchi, Rita, de Lascoiti, Angela Fernandez, De Mattos-Arruda, Leticia, Ignatiadis, Michail, Lebofsky, Ronald, van Laere, Steven J, Meier-Stiegen, Franziska, Sandri, Maria-Teresa, Vidal-Martinez, Jose, Politaki, Eleni, Consoli, Francesca, Bottini, Alberto, Diaz-Rubio, Eduardo, Krell, Jonathan, Dawson, Sarah-Jane, Raimondi, Cristina, Rutten, Annemie, Janni, Wolfgang, Munzone, Elisabetta, Carañana, Vicente, Agelaki, Sofia, Almici, Camillo, Dirix, Luc, Solomayer, Erich-Franz, Zorzino, Laura, Johannes, Helene, Reis-Filho, Jorge S, Pantel, Klaus, Pierga, Jean-Yves, and Michiels, Stefan
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- 2014
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21. Predictive value of PET-CT for pathological response in stages II and III breast cancer patients following neoadjuvant chemotherapy with docetaxel
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García García-Esquinas, Marta A., Arrazola García, Juan, García-Sáenz, José A., Furió-Bacete, V., Fuentes Ferrer, Manuel E., Ortega Candil, Aída, Cabrera Martín, María N., and Carreras Delgado, José L.
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- 2014
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22. Modeling the Prognostic Impact of Circulating Tumor Cells Enumeration in Metastatic Breast Cancer for Clinical Trial Design Simulation
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Gerratana, Lorenzo, primary, Pierga, Jean-Yves, additional, Reuben, James M, additional, Davis, Andrew A, additional, Wehbe, Firas H, additional, Dirix, Luc, additional, Fehm, Tanja, additional, Nolé, Franco, additional, Gisbert-Criado, Rafael, additional, Mavroudis, Dimitrios, additional, Grisanti, Salvatore, additional, Garcia-Saenz, Jose A, additional, Stebbing, Justin, additional, Caldas, Carlos, additional, Gazzaniga, Paola, additional, Manso, Luis, additional, Zamarchi, Rita, additional, Bonotto, Marta, additional, Fernandez de Lascoiti, Angela, additional, De Mattos-Arruda, Leticia, additional, Ignatiadis, Michail, additional, Sandri, Maria-Teresa, additional, Generali, Daniele, additional, De Angelis, Carmine, additional, Dawson, Sarah-Jane, additional, Janni, Wolfgang, additional, Carañana, Vicente, additional, Riethdorf, Sabine, additional, Solomayer, Erich-Franz, additional, Puglisi, Fabio, additional, Giuliano, Mario, additional, Pantel, Klaus, additional, Bidard, François-Clément, additional, and Cristofanilli, Massimo, additional
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- 2022
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23. Abstract P3-05-06: Genome-wide DNA methylation analysis identifies novel biomarkers associated with risk of relapse beyond oncotype DX recurrence-score risk assessment within HR+/HER2- early-stage breast cancer patients
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Fuentes-Antrás, Jesus, primary, García-Barberán, Vanesa, additional, Costa-Fraga, Nicolas, additional, Moreno, Fernando, additional, Bao-Caamano, Aida, additional, Rodríguez-Casanova, Aitor, additional, López de Sá, Alfonso, additional, De Luna, Alicia, additional, Lopez-Cade, Igor, additional, Ramirez-Ruda, Carmen, additional, Pascual, Alejando, additional, Perez-Segura, Pedro, additional, Győrffy, Balázs, additional, Ocaña, Alberto, additional, Diaz-Lagares, Angel, additional, and Garcia-Saenz, Jose Angel, additional
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- 2022
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24. Abstract P2-01-18: Orthogonal assessment of PIK3CA and ESR1 mutation detection in longitudinal cfDNA samples from endocrine-resistant HR+/HER2- advanced breast cancer patients using dPCR and NGS-based SafeSEQ technology
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Antras, Jesus Fuentes, primary, García-Barberán, Vanesa, additional, Moreno, Fernando, additional, Sloane, Hillary, additional, López-Cade, Igor, additional, De Luna, Alicia, additional, Pascual, Alejandro, additional, Ramirez-Ruda, Carmen, additional, Lorca, Victor, additional, Flores, Paloma, additional, Perez-Segura, Pedro, additional, Ocaña, Alberto, additional, Preston, Jennifer, additional, Quinn, Hannah, additional, Jones, Frederick, additional, and Garcia-Saenz, Jose Angel, additional
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- 2022
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25. Assessment of Topoisomerase II α Status in Breast Cancer by Quantitative PCR, Gene Expression Microarrays, Immunohistochemistry, and Fluorescence in Situ Hybridization
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Romero, Atocha, Martín, Miguel, Cheang, Maggie C.U., López García-Asenjo, José Antonio, Oliva, Belén, He, Xiaping, de la Hoya, Miguel, García Sáenz, Jose Ángel, Arroyo Fernández, Manuel, Díaz Rubio, Eduardo, Perou, Charles M., and Llopis, Trinidad Caldés
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- 2011
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26. Clinical utility of repeated circulating tumor cell (CTC) enumeration as early treatment monitoring tool in metastatic breast cancer (MBC) - a global pooled analysis with individual patient data
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Janni, Wolfgang J., Yab, Tracy C., Hayes, Daniel F., Cristofanilli, Massimo, Bidard, Francois-Clement, Ignatiadis, Michail, Regan, Meredith M., Alix-Panabieres, Catherine, Barlow, William E., Carlos Caldas, Carey, Lisa A., Dirix, Luc, Fehm, Tanja, Garcia-Saenz, Jose A., Gazzaniga, Paola, Generali, Daniele, Gerratana, Lorenzo, Gisbert-Criado, Rafael, Jacot, William, Jiang, Zefei, Lianidou, Evi, Magbanua, Mark J. M., Manso, Luis, Mavroudis, Dimitrios, Muller, Volkmar, Munzone, Elisabetta, Pantel, Klaus, Pierga, Jean-Yves, Rack, Brigitte, Riethdorf, Sabine, Rugo, Hope S., Sideras, Kostandinos, Sleijfer, Stefan, Smerage, Jeffrey, Stebbing, Justin, Terstappen, Leon W. M. M., Vidal-Martinez, Jose, Zamarchi, Rita, Giridhar, Karthik, Friedl, Thomas W. P., and Liu, Minetta C.
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- 2021
27. Safety and efficacy of cyclin-dependent kinase inhibitor rechallenge following ribociclib-induced limiting hypertransaminasemia
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Fuentes-Antrás, Jesús, de Luna, Alicia, López de Sá, Alfonso, Ocaña, Alberto, García-Sáenz, José Ángel, and Moreno, Fernando
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- 2020
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28. Abstract GS4-08: Clinical utility of repeated circulating tumor cell (CTC) enumeration as early treatment monitoring tool in metastatic breast cancer (MBC) - a global pooled analysis with individual patient data
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Janni, Wolfgang J, primary, Yab, Tracy C., additional, Hayes, Daniel F., additional, Cristofanilli, Massimo, additional, Bidard, Francois-Clement, additional, Ignatiadis, Michail, additional, Regan, Meredith M., additional, Alix-Panabières, Catherine, additional, Barlow, William E., additional, Caldas, Carlos, additional, Carey, Lisa A., additional, Dirix, Luc, additional, Fehm, Tanja, additional, Garcia-Saenz, Jose A., additional, Gazzaniga, Paola, additional, Generali, Daniele, additional, Gerratana, Lorenzo, additional, Gisbert-Criado, Rafael, additional, Jacot, William, additional, Jiang, Zefei, additional, Lianidou, Evi, additional, Magbanua, Mark J.M., additional, Manso, Luis, additional, Mavroudis, Dimitrios, additional, Müller, Volkmar, additional, Munzone, Elisabetta, additional, Pantel, Klaus, additional, Pierga, Jean-Yves, additional, Rack, Brigitte, additional, Riethdorf, Sabine, additional, Rugo, Hope S., additional, Sideras, Kostandinos, additional, Sleijfer, Stefan, additional, Smerage, Jeffrey, additional, Stebbing, Justin, additional, Terstappen, Leon W.M.M., additional, Vidal-Martínez, José, additional, Zamarchi, Rita, additional, Giridhar, Karthik, additional, Friedl, Thomas W.P., additional, and Liu, Minetta C., additional
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- 2021
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29. Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer (KEYNOTE-355): a randomised, placebo-controlled, double-blind, phase 3 clinical trial
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Vassiliki Karantza, Shparyk Yaroslav, Sumrall Bradley, Javier Cortes, Iwata Hiroji, Kolesnik Oleksii, Ahn Jin Hee, Harbeck Nadia, Prausova Jana, Song Xinni, Berzoy Oleksandr, Mena Raul, Osaki Akihiko, Kahan Zsuzsanna, Simon Michael, Ozguroglu Mustafa, Chmielowska Ewa, Tsugawa Koichiro, Tsao Chao-Jung, Ozyilkan Ozgur, Nowecki Zbigniew, Fadeeva Natalia, Kaen Diego, Garcia Saenz Jose, Porter David, Ngan Kai Cheong Roger, Sherene Loi, Bermejo de las Heras Begona, Turner Nicholas, David W. Cescon, Hope S. Rugo, Oliff Ira, Kelly Catherine, Barrios Carlos, Cole Scott, Shevnya Sergii, Seock-Ah Im, Hoskins Kent, Komisarenko Hanna, Yavuz Sinan, Chaudhry Madhu, Sagara Yasuaki, Brust Leandro, Chan Steve, Gomez Villanueva Angel, Gallardo Carlos, Watanabe Junichiro, Ishikawa Takashi, Schleider Michael, Salas Claudio, Hardy-Bessard Anne-Claire, Erhan Gokmen, Adamchuk Hryhoriy, Beelen Karin, Holeckova Petra, Szczylik Cezary, Fujii Takaaki, Nakamura Seigo, Aruga Tomoyuki, Gokmen Erhan, Jing Zhao, Hiroji Iwata, Molinas Mandel Nil, Gogineni Keerthi, Im Seock-Ah, Zifang Guo, Loi Sherene, Costa Fabiano, Forstmeyer Dirk, Kosaka Yoshimasa, Gomez Diaz Alvaro, Ponomarova Olga, Wimberger Pauline, DAlessio Antonietta, Suzuki Eiji, Blohmer Jens-Uwe, Kowalwszyn Ruben, Molina Matias, Clingan Philip, Yamamoto Yutaka, Sabanathan Dhanusha, Gursel Aktan, Vynnychenko Ihor, Ferrario Cristiano, Schumann Raquel Von, Trukhin Dmytro, Arkosy Peter, Tseng Ling-Ming, Moore Susan, Gunduz Seyda, Stampleman Laura, de Freitas Junior Ruffo, Acevedo Alejandro, Lipatov Oleg, Niikura Naoki, Norikazu Masuda, Rusyn Andrii, Kral Zdenek, Crown John, Yamamoto Naohito, Jakobsen Erik, Blau Sibel, Bustam Anita, Zamora Adelantado Esther, Nanda Rita, Omene Coral, Arslan Cagatay, Kwong Ava, Teixeira Luis, Jensen Jeanette, Ito Yoshinori, Siegel Robert, Mastura Md Yusof, Nowakowska-Zajdel Ewa, Miyoshi Yasuo, Yu Joanne, Tuthill Mark, Mukhametshina Guzel, Matsumoto Koji, Gion Maria, Melichar Bohuslav, Desmoulins Isabelle, Moiseyenko Vladimir, Zurawski Bogdan, Carlos Gallardo, Lorincz Tamas, Cruz Jurado Josefina, Bondarenko Igor, Kaczerowsky Flores de Sousa Anna, Yamauchi Teruo, Loutfi Randa, Esther Holgado, Holgado Esther, Twelves Christopher, Streb Joanna, Tanabe Yuko, Tarnawski Rafal, Morales-Vasquez Flavia, Park Kwong Hwa, Csoszi Tibor, Meshcheryakov Andrey, Scalabrini Neto Antonio Orlando, Oleg Lipatov, Iwasa Tsutomu, Ricevuto Enrico, Tamura Kenji, Patson Brian, Liu Mei-Ching, Cinieri Saverio, Loibl Sibylle, Tjan-Heijnen Vivianne, Glavicic Vesna, Panwalkar Amit, Hargis Jeffrey, Kryzhanivska Anna, Yusof Mastura, O'Reilly Seamus, Rubovszky Gabor, Irvin William, Takahashi Masato, Ohtani Shoichiro, Peter Schmid, Carlos H. Barrios, Sanchez Cesar, Zbigniew Nowecki, Arkhipov Alexander, Chung Michael, Liu Chien-Ting, Mukai Hirofumi, Marco Torregroza Otero, Charpentier Danielle, Park-Simon Tjoung-Won, Lee Keun Seok, Leshchenko Iurii, Huang Chiun-Sheng, Tsai Michaela, Panella Timothy, Petrakova Katarina, MacPherson Iain, Schmid Peter, Baron-Hay Sally, Ursol Grygorii, Lacerda Domicio Carvalho, Cobb Patrick, Sanchez Jesus, Park Yeon Hee, Reyes Contreras Jessica, Fein Luis, Hegg Roberto, Diamond Jennifer, Huober Jens, Rugo Hope, Rybalova Irina, de la Cruz Merino Luis, Linnet Soren, Inoue Kenichi, Wheatley Duncan, Cescon David, Cicin Irfan, Gombos Andrea, Bonnefoi Herve, Nasonova Alla, Taylor Donatienne, Martinez Rodriguez Jorge, Valdes-Albini Frances, Juarez Ramiro Alejandro, Cortes Javier, Lu Janice, Silva Felipe, Lueftner Diana, Landherr Laszlo, Gomez Abuin Gonzalo, Yanez Eduardo, Rocha Roberto Odebrecht, Chow Louis, Otchenash Natalya, Radecka Barbara, Kolesnik Olena, Basaran Gul, Kurbacher Christian, Mahr Karoly, Goncalves Anthony, Begbie Stephen, Graham Janine, Fasching Peter, Varela Mirta, and Lissa Fernando Cezar Toniazzi
- Subjects
Oncology ,double blind procedure ,pharmacist ,CD274 protein, human ,hazard ratio ,0302 clinical medicine ,middle aged ,Antineoplastic Combined Chemotherapy Protocols ,cancer survival ,comparative study ,education.field_of_study ,progression free survival ,adult ,drug effect ,gemcitabine ,clinical trial ,General Medicine ,nausea ,anemia ,Progression-Free Survival ,priority journal ,immunological antineoplastic agent ,thyroiditis ,pembrolizumab ,metastatic breast cancer ,neoadjuvant chemotherapy ,medicine.medical_specialty ,Antineoplastic Agents ,intention to treat analysis ,Article ,skin manifestation ,03 medical and health sciences ,Breast cancer ,cancer combination chemotherapy ,neutropenia ,Humans ,Progression-free survival ,human ,education ,protein expression ,cancer immunotherapy ,treatment response ,Interim analysis ,medicine.disease ,major clinical study ,tumor recurrence ,Carboplatin ,programmed death 1 ligand 1 ,drug efficacy ,multicenter study ,chemistry ,monoclonal antibody ,randomized controlled trial ,fatigue ,drug tolerability ,cancer patient ,age distribution ,drug safety ,colitis ,clinical outcome ,Triple Negative Breast Neoplasms ,Pembrolizumab ,030204 cardiovascular system & hematology ,B7-H1 Antigen ,Placebos ,chemistry.chemical_compound ,paclitaxel ,Antineoplastic Agents, Immunological ,Outcome Assessment, Health Care ,030212 general & internal medicine ,antineoplastic agent ,cancer adjuvant therapy ,Eastern Cooperative Oncology Group performance status ,female ,carboplatin ,sodium chloride ,immunohistochemistry ,medicine.drug ,interactive voice response system ,alanine aminotransferase ,overall survival ,Population ,Antibodies, Monoclonal, Humanized ,Double-Blind Method ,Internal medicine ,medicine ,follow up ,hyperthyroidism ,pneumonia ,controlled study ,Taxane ,phase 3 clinical trial ,business.industry ,hypertransaminasemia ,alopecia ,Gemcitabine ,human tissue ,cancer recurrence ,functional status assessment ,triple negative breast cancer ,placebo ,inoperable cancer ,pathology ,hypothyroidism ,Neoplasm Recurrence, Local ,business ,metabolism ,Follow-Up Studies - Abstract
Background: Pembrolizumab monotherapy showed durable antitumour activity and manageable safety in patients with metastatic triple-negative breast cancer. We aimed to examine whether the addition of pembrolizumab would enhance the antitumour activity of chemotherapy in patients with metastatic triple-negative breast cancer. Methods: In this randomised, placebo-controlled, double-blind, phase 3 trial, done in 209 sites in 29 countries, we randomly assigned patients 2:1 with untreated locally recurrent inoperable or metastatic triple-negative breast cancer using a block method (block size of six) and an interactive voice-response system with integrated web-response to pembrolizumab (200 mg) every 3 weeks plus chemotherapy (nab-paclitaxel; paclitaxel; or gemcitabine plus carboplatin) or placebo plus chemotherapy. Randomisation was stratified by type of on-study chemotherapy (taxane or gemcitabine–carboplatin), PD-L1 expression at baseline (combined positive score [CPS] ?1 or, Breast Cancer Research Foundation, BCRF; Pfizer; AstraZeneca; Merck; Roche; Samsung; Merck Sharp and Dohme, MSD; Eisai, JC reports personal fees and research funding paid to his institution from Roche, AstraZeneca, Merck Sharp & Dohme, and Eisai; personal fees from Celgene, Cellestia, Biothera Pharmaceutical, Merus, Seattle Genetics, Daiichi Sankyo, Erytech, Athenex, Polyphor, Lilly, Servier, GlaxoSmithKline, Leuko, Bioasis, Clovis Oncology, Boehringer Ingelheim, Kyowa Kirin, Novartis, Pfizer, Samsung Bioepis; research funding paid to his institution from Ariad Pharmaceuticals, Bayer Healthcare, F Hoffman-La Roche, Guardanth Health, Piqur Therapeutics, Puma C, and Queen Mary University of London, outside the submitted work. In addition, JC has a MedSIR patent pending. DWC reports research support from Merck during the conduct of the study; research support paid to his institution from Merck, Pfizer, and GlaxoSmithKline; personal fees from Merck, Roche–Genentech, AstraZeneca, GlaxoSmithKline, Novartis, Pfizer, Puma, Agenda, Exact Sciences, and Dynamo Therapeutics, outside the submitted work. In addition, DWC has a Biomarkers of TTK inhibitors patent pending. HSR reports funding for sponsored studies paid to the University of California San Francisco from Pfizer, Novartis, Lilly, Roche–Genentech, Macrogenics, OBI, Merck, Eisai, Immunomedics, Daiichi Sankyo, Seattle Genetics, and Odonate; travel support for educational meetings from Daiichi Sankyo, Mylan, Pfizer, Merck, AstraZeneca, Novartis, and Macrogenics; and consulting fees from Samsung and Puma, outside the submitted work. S-AI reports grants from AstraZeneca, Eisai, Pfizer, Roche, and Daewoong; an advisory role for AstraZeneca, Amgen, Eisai, Hanmi, Novartis, Lily, MedPacto, Pfizer, and Roche; and travel expenses for presentation from Novartis, outside the submitted work. CG reports Advisory Board fees from Merck Sharp & Dohme and Roche; and speaker's bureau fees from Bristol Myers Squibb and AstraZeneca, outside the submitted work. CHB reports grants and fees from Merck Sharp & Dohme for clinical research consulting during the conduct of the study; consulting–advisory role fees from Boehringer Ingelheim, GlaxoSmithKline, and Bayer; consulting–advisory role fees and grants for clinical research from Novartis, Pfizer, Roche–Genentech, Eisai, Merck Sharp & Dohme, and AstraZeneca; grants for clinical research from Abbvie, Amgen, Astellas Pharma, Bristol Myers Squibb, Celgene, Covance, Lilly, Medication, Merck Serono, and PharmaMar; grants for academic research projects from CPO, Pontificia Universidade Católica do Rio Grande do Sul, Latin American Cooperative Oncology Group, Grupo Brasileiro Estudos Câncer Mama, and Instituto Nacional de Câncer-Brazil, outside the submitted work. HI reports a grant from Merck Sharp & Dohme during the conduct of the study; honoraria and consulting fees from Novartis, AstraZeneca, Pfizer, Lilly, Daiichi Sankyo, Eisai, and Chugai; and a grant from Chugai, outside the submitted work. NM reports honoraria and research funding paid to his institution from Chugai, AstraZeneca, Pfizer, Eli-Lilly, Eisai, Takeda, Kyowa-Kirin, Merck Sharp & Dohme, Novartis, and Daiichi Sankyo, outside the submitted work. EG reports non-financial support from Merck Sharp & Dohme during the conduct of the study; honoraria, consulting–advisory fees and meeting support from Novartis, Roche, Bristol Myers Squibb, and Pfizer; and honoraria from AstraZeneca and Astellas, outside the submitted work. SL reports research funding or consulting fees paid to her institution from Bristol Myers Squibb, Roche–Genentech, Puma Biotechnology, Pfizer, Seattle Genetics, Novartis, Merck Sharp & Dohme, Eli Lilly, Aduro Biotech, GI Therapeutics, AstraZeneca, and GlaxoSmithKline; and non-remunerated consultancy for Bristol Myers Squibb, Roche–Genentech, Pfizer, Seattle Genetics, Novartis, Merck Sharp & Dohme, and AstraZeneca, outside the submitted work. In addition, SL is supported by the National Breast Cancer Foundation of Australia Endowed Chair and the Breast Cancer Research Foundation, New York. ZG, JZ, GA, and VK are employees of Merck Sharp & Dohme and own stock or stock options in Merck. PS reports consultancy fees from Pfizer, AstraZeneca, Novartis, Roche, Merck Sharp & Dohme, Boehringer Ingelheim, Bayer, Eisai, Celgene, and Puma; consultancy fees to his spouse from Genentech and Roche; and grants or funding to his institution from Roche, Genentech, Oncogenex, Novartis, Astellas, and AstraZeneca, outside the submitted work. All other authors declare no competing interests., The authors thank the patients, their families and caregivers for participating in this trial, all of the investigators and site personnel, and the following employees of Merck Sharp & Dohme: Wilbur Pan, Deborah Card, Eleanor Readinger, Shana Hamm, Roger Maxwell, and Krystal Bourdon, for collection of data, supervision of research, provision of study materials or patients or administrative or logistical support; Aline Galvao, for collection of data, supervision of research, administrative or logistical support, and review of imaging data related to the primary end point; Donna Letizia, for collection of data and imaging expertise; Jennifer Kimmel, for study management; Mercedes Bustamante, for data collection and management; Xuan Zhou and Madhusudhan Reddy Papasani, for statistical expertise; Christine McCrary Sisk, for medical writing and editorial assistance; and Joseph C Naggar and Michele McColgan, for administrative or logistical support.
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- 2020
30. Gemcitabine plus vinorelbine versus vinorelbine monotherapy in patients with metastatic breast cancer previously treated with anthracyclines and taxanes: final results of the phase III Spanish Breast Cancer Research Group (GEICAM) trial
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Martín, Miguel, Ruiz, Amparo, Muñoz, Monserrat, Balil, Ana, García-Mata, Jesús, Calvo, Lourdes, Carrasco, Eva, Mahillo, Esther, Casado, Antonio, García-Saenz, José Ángel, Escudero, M José, Guillem, Vicente, Jara, Carlos, Ribelles, Nuria, Salas, Fernando, Soto, Celia, Morales-Vasquez, Flavia, Rodríguez, César A, Adrover, Encarna, and Mel, José Ramón
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- 2007
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31. Abemaciclib, a CDK4 and CDK6 inhibitor for the treatment of metastatic breast cancer
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Martin, Miguel, primary, Garcia-Saenz, Jose A, additional, Manso, Luis, additional, Llombart, Antonio, additional, Cassinello, Alejo, additional, Atienza, Manuel, additional, Ringeisen, Francois, additional, and Ciruelos, Eva, additional
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- 2020
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32. Serial Analysis of Circulating Tumor Cells in Metastatic Breast Cancer Receiving First-Line Chemotherapy
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Magbanua, Mark Jesus M, primary, Hendrix, Laura H, additional, Hyslop, Terry, additional, Barry, William T, additional, Winer, Eric P, additional, Hudis, Clifford, additional, Toppmeyer, Deborah, additional, Carey, Lisa Anne, additional, Partridge, Ann H, additional, Pierga, Jean-Yves, additional, Fehm, Tanja, additional, Vidal-Martínez, José, additional, Mavroudis, Dimitrios, additional, Garcia-Saenz, Jose A, additional, Stebbing, Justin, additional, Gazzaniga, Paola, additional, Manso, Luis, additional, Zamarchi, Rita, additional, Antelo, María Luisa, additional, Mattos-Arruda, Leticia De, additional, Generali, Daniele, additional, Caldas, Carlos, additional, Munzone, Elisabetta, additional, Dirix, Luc, additional, Delson, Amy L, additional, Burstein, Harold J, additional, Qadir, Misbah, additional, Ma, Cynthia, additional, Scott, Janet H, additional, Bidard, François-Clément, additional, Park, John W, additional, and Rugo, Hope S, additional
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- 2020
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33. Monitoring of PIK3CA and ESR1 mutations in circulating tumor DNA as predictive and prognostic biomarkers in patients with endocrine-resistant ER+/HER2- advanced breast cancer.
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Fuentes Antrás, Jesús, primary, García-Barberán, Vanesa, additional, Gonzalo, Irene, additional, Moreno, Fernando, additional, López-Cade, Igor, additional, Ramírez-Ruda, Carmen, additional, Bueno, Oskia, additional, Ascaso del Rio, Ana, additional, Pascual, Alejandro, additional, Ocana, Alberto, additional, Caldes, Trinidad, additional, and Garcia-Saenz, Jose Angel, additional
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- 2020
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34. Serum phospholipids fatty acids and breast cancer risk by pathological subtype: EpiGEICAM study.
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Pollan, Marina, primary, Lope, Virginia, additional, Guerrero-Zotano, Angel, additional, Casas, Ana, additional, Baena-Cañada, José Manuel, additional, Bermejo, Begoña, additional, Perez-Gomez, Beatriz, additional, Sanchez-Rovira, Pedro, additional, Ramos Vazquez, Manuel, additional, Anton, Antonio, additional, Garcia-Saenz, Jose Angel, additional, Munoz, Montserrat, additional, de Juan, Ana, additional, Andres, Raquel, additional, Llombart Cussac, Antonio, additional, Hernando, Blanca, additional, Franquesa, Rosa María, additional, Caballero, Rosalia, additional, Martin, Miguel, additional, and Priego, Feliciano, additional
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- 2020
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35. Trastuzumab Associated with Successive Cytotoxic Therapies Beyond Disease Progression in Metastatic Breast Cancer
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García-Sáenz, José A., Martín, Miguel, Puente, Javier, López-Tarruella, Sara, Casado, Antonio, Moreno, Fernando, Grande, Enrique, and Díaz-Rubio, Eduardo
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- 2005
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36. Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes
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Fachal, Laura, Aschard, Hugues, Beesley, Jonathan, Barnes, Daniel, Allen, Jamie, Kar, Siddhartha, Pooley, Karen, Dennis, Joe, Michailidou, Kyriaki, Turman, Constance, Soucy, Penny, Lemacon, Audrey, Lush, Michael, Tyrer, Jonathan, Ghoussaini, Maya, Moradi Marjaneh, Mahdi, Jiang, Xia, Agata, Simona, Aittomaki, Kristiina, Alonso, M. Rosario, Andrulis, Irene, Anton-Culver, Hoda, Antonenkova, Natalia, Arason, Adalgeir, Arndt, Volker, Aronson, Kristan, Arun, Banu, Auber, Bernd, Auer, Paul, Azzollini, Jacopo, Balmana, Judith, Barkardottir, Rosa, Barrowdale, Daniel, Beeghly-Fadiel, Alicia, Benitez, Javier, Bermisheva, Marina, Bialkowska, Katarzyna, Blanco, Amie, Blomqvist, Carl, Blot, William, Bogdanova, Natalia, Bojesen, Stig, Bolla, Manjeet, Bonanni, Bernardo, Borg, Ake, Bosse, Kristin, Brauch, Hiltrud, Brenner, Hermann, Briceno, Ignacio, Brock, Ian, Brooks-Wilson, Angela, Bruning, Thomas, Burwinkel, Barbara, Buys, Saundra, Cai, Qiuyin, Caldes, Trinidad, Caligo, Maria, Camp, Nicola, Campbell, Ian, Canzian, Federico, Carroll, Jason, Carter, Brian, Castelao, Jose, Chiquette, Jocelyne, Christiansen, Hans, Chung, Wendy, Claes, Kathleen, Clarke, Christine, Collee, J. Margriet, Cornelissen, Sten, Couch, Fergus, Cox, Angela, Cross, Simon, Cybulski, Cezary, Czene, Kamila, Daly, Mary, de la Hoya, Miguel, Devilee, Peter, Diez, Orland, Ding, Yuan Chun, Dite, Gillian, Domchek, Susan, Dork, Thilo, dos-Santos-Silva, Isabel, Droit, Arnaud, Dubois, Stephane, Dumont, Martine, Duran, Mercedes, Durcan, Lorraine, Dwek, Miriam, Eccles, Diana, Engel, Christoph, Eriksson, Mikael, Evans, D. Gareth, Fasching, Peter, Fletcher, Olivia, Floris, Giuseppe, Flyger, Henrik, Foretova, Lenka, Foulkes, William, Friedman, Eitan, Fritschi, Lin, Frost, Debra, Gabrielson, Marike, Gago-Dominguez, Manuela, Gambino, Gaetana, Ganz, Patricia, Gapstur, Susan, Garber, Judy, Garcia-Saenz, Jose, Gaudet, Mia, Georgoulias, Vassilios, Giles, Graham, Glendon, Gord, Godwin, Andrew, Goldberg, Mark, Goldgar, David, Gonzalez-Neira, Anna, Greene, Mark, Grip, Mervi, Gronwald, Jacek, Grundy, Anne, Guenel, Pascal, Hahnen, Eric, Haiman, Christopher, Hakansson, Niclas, Hall, Per, Hamann, Ute, Harrington, Patricia, Hartikainen, Jaana, Hartman, Mikael, He, Wei, Healey, Catherine, Heemskerk-Gerritsen, Bernadette, Heyworth, Jane, Hillemanns, Peter, Hogervorst, Frans, Hollestelle, Antoinette, Hooning, Maartje, Hopper, John, Howell, Anthony, Huang, Guanmengqian, Hulick, Peter, Imyanitov, Evgeny, Isaacs, Claudine, Iwasaki, Motoki, Jager, Agnes, Jakimovska, Milena, Jakubowska, Anna, James, Paul, Janavicius, Ramunas, Jankowitz, Rachel, John, Esther, Johnson, Nichola, Jones, Michael, Jukkola-Vuorinen, Arja, Jung, Audrey, Kaaks, Rudolf, Kang, Daehee, Karlan, Beth, Keeman, Renske, Kerin, Michael, Khusnutdinova, Elza, Kiiski, Johanna, Kirk, Judy, Kitahara, Cari, Ko, Yon-Dschun, Konstantopoulou, Irene, Kosma, Veli-Matti, Koutros, Stella, Kubelka-Sabit, Katerina, Kwong, Ava, Kyriacou, Kyriacos, Laitman, Yael, Lambrechts, Diether, Lee, Eunjung, Leslie, Goska, Lester, Jenny, Lesueur, Fabienne, Lindblom, Annika, Lo, Wing-Yee, Long, Jirong, Lophatananon, Artitaya, Loud, Jennifer, Lubinski, Jan, MacInnis, Robert, Maishman, Tom, Makalic, Enes, Mannermaa, Arto, Manoochehri, Mehdi, Manoukian, Siranoush, Margolin, Sara, Martinez, Maria Elena, Matsuo, Keitaro, Maurer, Tabea, Mavroudis, Dimitrios, Mayes, Rebecca, McGuffog, Lesley, McLean, Catriona, Mebirouk, Noura, Meindl, Alfons, Middha, Pooja, Miller, Nicola, Miller, Austin, Montagna, Marco, Moreno, Fernando, Mulligan, Anna Marie, Munoz-Garzon, Victor, Muranen, Taru, Narod, Steven, Nassir, Rami, Nathanson, Katherine, Neuhausen, Susan, Nevanlinna, Heli, Neven, Patrick, Nielsen, Finn, Nikitina-Zake, Liene, Norman, Aaron, Offit, Kenneth, Olah, Edith, Olopade, Olufunmilayo, Olsson, Hakan, Orr, Nick, Osorio, Ana, Pankratz, V. Shane, Papp, Janos, Park, Sue, Park-Simon, Tjoung-Won, Parsons, Michael, Paul, James, Pedersen, Inge Sokilde, Peissel, Bernard, Peshkin, Beth, Peterlongo, Paolo, Peto, Julian, Plaseska-Karanfilska, Dijana, Prajzendanz, Karolina, Prentice, Ross, Presneau, Nadege, Prokofyeva, Darya, Pujana, Miquel Angel, Pylkas, Katri, Radice, Paolo, Ramus, Susan, Rantala, Johanna, Rau-Murthy, Rohini, Rennert, Gad, Risch, Harvey, Robson, Mark, Romero, Atocha, Rossing, Caroline Maria, Saloustros, Emmanouil, Sanchez-Herrero, Estela, Sandler, Dale, Santamarina, Marta, Saunders, Christobel, Sawyer, Elinor, Scheuner, Maren, Schmidt, Daniel, Schmutzler, Rita, Schneeweiss, Andreas, Schoemaker, Minouk, Schottker, Ben, Schurmann, Peter, Scott, Christopher, Scott, Rodney, Senter, Leigha, Seynaeve, Caroline, Shah, Mitul, Sharma, Priyanka, Shen, Chen-Yang, Shu, Xiao-Ou, Singer, Christian, Slavin, Thomas, Smichkoska, Snezhana, Southey, Melissa, Spinelli, John, Spurdle, Amanda, Stone, Jennifer, Stoppa-Lyonnet, Dominique, Sutter, Christian, Swerdlow, Anthony, Tamimi, Rulla, Tan, Yen Yen, Tapper, William, Taylor, Jack, Teixeira, Manuel, Tengstrom, Maria, Teo, Soo, Terry, Mary Beth, Teule, Alex, Thomassen, Mads, Thull, Darcy, Tibiletti, Maria Grazia, Tischkowitz, Marc, Toland, Amanda, Tollenaar, Rob, Tomlinson, Ian, Torres, Diana, Torres-Mejia, Gabriela, Troester, Melissa, Tung, Nadine, Tzardi, Maria, Ulmer, Hans-Ulrich, Vachon, Celine, van Asperen, Christi, van der Kolk, Lizet, van Rensburg, Elizabeth, Vega, Ana, Viel, Alessandra, Vijai, Joseph, Vogel, Maatje, Wang, Qin, Wappenschmidt, Barbara, Weinberg, Clarice, Weitzel, Jeffrey, Wendt, Camilla, Wildiers, Hans, Winqvist, Robert, Wolk, Alicja, Wu, Anna, Yannoukakos, Drakoulis, Zhang, Yan, Zheng, Wei, Pharoah, Paul, Chang-Claude, Jenny, Garcia-Closas, Montserrat, Schmidt, Marjanka, Milne, Roger, Kristensen, Vessela, French, Juliet, Edwards, Stacey, Antoniou, Antonis, Chenevix-Trench, Georgia, Simard, Jacques, Easton, Douglas, Kraft, Peter, and Dunning, Alison
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0303 health sciences ,Linkage disequilibrium ,In silico ,Computational biology ,Biology ,3. Good health ,Chromatin ,DNA binding site ,03 medical and health sciences ,0302 clinical medicine ,030220 oncology & carcinogenesis ,Expression quantitative trait loci ,Transcription factor ,Gene ,030304 developmental biology ,Genetic association - Abstract
Genome-wide association studies have identified breast cancer risk variants in over 150 genomic regions, but the mechanisms underlying risk remain largely unknown. These regions were explored by combining association analysis with in silico genomic feature annotations. We defined 205 independent risk-associated signals with the set of credible causal variants (CCVs) in each one. In parallel, we used a Bayesian approach (PAINTOR) that combines genetic association, linkage disequilibrium, and enriched genomic features to determine variants with high posterior probabilities (HPPs) of being causal. Potentially causal variants were significantly over-represented in active gene regulatory regions and transcription factor binding sites. We applied our INQUSIT pipeline for prioritizing genes as targets of potentially causal variants, using gene expression (eQTL), chromatin interaction and functional annotations. Known cancer drivers, transcription factors and genes in the developmental, apoptosis, immune system and DNA integrity checkpoint gene ontology pathways, were over-represented among the 178 highest confidence target genes.
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- 2019
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37. Phase II Study of Pegylated Liposomal Doxorubicin plus Vinorelbine in Breast Cancer with Previous Anthracycline Exposure
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Martin, Miguel, García-Donas, Jesus, Casado, Antonio, de la Gándara, Isabel, Pérez-Segura, Pedro, García-Saenz, Jose-Angel, Ibáñez, Gabriel, Loboff, Belen, García-Ledo, Gemma, Moreno, Fernando, Grande, Enrique, and Diaz-Rubio, Eduardo
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- 2004
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38. Vinorelbine as a 96-Hour Continuous Infusion in Heavily Pretreated Patients with Metastatic Breast Cancer: A Cooperative Study by the GEICAM Group
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Jara-Sánchez, Carlos, Martín, Miguel, García-Sáenz, Jose A., Barnadas, Agustí, Fernández-Aramburo, Antonio, López-Vega, Jose M., Pelegrí, Amadeu, Alba, Emilio, and Casado, Antonio
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- 2003
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39. DICEP high dose chemotherapy with or without peripheral blood stem cell support as consolidation treatment in young adults with high risk Ewing's sarcoma and family of tumors.
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Casado, Antonio, Manrique, Isabel, Martin, Miguel, Carbonero, Itziar Garcia, Garcia-Saenz, Jose Angel, Oruezabal, Mauro, Flores, Luis, Camara, Juan Carlos, Carreño, Ramiro, and Rubio, Eduardo Diaz
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- 2000
40. The impact of circulating tumor cells (CTCs) detection in metastatic breast cancer (MBC): Implications of “indolent” stage IV disease (Stage IVindolent).
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Davis, Andrew A., primary, Pierga, Jean-Yves, additional, Dirix, Luc Yves, additional, Michiels, Stefan, additional, Rademaker, Alfred, additional, Reuben, James M., additional, Fehm, Tanja N., additional, Munzone, Elisabetta, additional, Giuliano, Mario, additional, Vidal-Martinez, Jose, additional, Mavroudis, Dimitrios, additional, Grisanti, Salvatore, additional, Generali, Daniele Giulio, additional, Garcia-Saenz, Jose Angel, additional, Stebbing, Justin, additional, Dawson, Sarah-Jane, additional, Gazzaniga, Paola, additional, Bidard, François-Clément, additional, and Cristofanilli, Massimo, additional
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- 2018
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41. Dietary inflammatory index and breast cancer risk by menopausal status and histological subtype.
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Castello, Adela, primary, Shivappa, Nitin, additional, Ruiz, Amparo, additional, Casas, Ana, additional, Lluch Hernandez, Ana, additional, Baena-Cañada, José Manuel, additional, Antolin, Silvia, additional, Sánchez Rovira, Pedro, additional, Ramos Vazquez, Manuel, additional, Garcia-Saenz, Jose Angel, additional, Anton, Antonio, additional, Munoz, Montserrat, additional, de Juan, Ana, additional, Jara-Sanchez, Carlos, additional, Vioque, Jesus, additional, Perez-Gomez, Beatriz, additional, Hébert, James R., additional, Lope, Virginia, additional, Martin, Miguel, additional, and Pollan, Marina, additional
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- 2018
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42. Circulating Tumor Cells in Breast Cancer Patients Treated by Neoadjuvant Chemotherapy: A Meta-analysis
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Bidard, François-Clément, primary, Michiels, Stefan, additional, Riethdorf, Sabine, additional, Mueller, Volkmar, additional, Esserman, Laura J, additional, Lucci, Anthony, additional, Naume, Bjørn, additional, Horiguchi, Jun, additional, Gisbert-Criado, Rafael, additional, Sleijfer, Stefan, additional, Toi, Masakazu, additional, Garcia-Saenz, Jose A, additional, Hartkopf, Andreas, additional, Generali, Daniele, additional, Rothé, Françoise, additional, Smerage, Jeffrey, additional, Muinelo-Romay, Laura, additional, Stebbing, Justin, additional, Viens, Patrice, additional, Magbanua, Mark Jesus M, additional, Hall, Carolyn S, additional, Engebraaten, Olav, additional, Takata, Daisuke, additional, Vidal-Martínez, José, additional, Onstenk, Wendy, additional, Fujisawa, Noriyoshi, additional, Diaz-Rubio, Eduardo, additional, Taran, Florin-Andrei, additional, Cappelletti, Maria Rosa, additional, Ignatiadis, Michail, additional, Proudhon, Charlotte, additional, Wolf, Denise M, additional, Bauldry, Jessica B, additional, Borgen, Elin, additional, Nagaoka, Rin, additional, Carañana, Vicente, additional, Kraan, Jaco, additional, Maestro, Marisa, additional, Brucker, Sara Yvonne, additional, Weber, Karsten, additional, Reyal, Fabien, additional, Amara, Dominic, additional, Karhade, Mandar G, additional, Mathiesen, Randi R, additional, Tokiniwa, Hideaki, additional, Llombart-Cussac, Antonio, additional, Meddis, Alessandra, additional, Blanche, Paul, additional, d'Hollander, Koenraad, additional, Cottu, Paul, additional, Park, John W, additional, Loibl, Sibylle, additional, Latouche, Aurélien, additional, Pierga, Jean-Yves, additional, and Pantel, Klaus, additional
- Published
- 2018
- Full Text
- View/download PDF
43. Safety and tolerability of subcutaneous trastuzumab for the adjuvant treatment of human epidermal growth factor receptor 2-positive early breast cancer: SafeHer phase III study's primary analysis of 2573 patients
- Author
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Gligorov, J., primary, Ataseven, B., additional, Verrill, M., additional, De Laurentiis, M., additional, Jung, K.H., additional, Azim, H.A., additional, Al-Sakaff, N., additional, Lauer, S., additional, Shing, M., additional, Pivot, X., additional, Koroveshi, Dhurata, additional, Bouzid, Kamel, additional, Casalnuovo, Monica, additional, Cascallar, Diana, additional, Korbenfeld, Ernesto Pablo, additional, Bastick, Patricia, additional, Beith, Jane, additional, Colosimo, Maree, additional, Friedlander, Michael, additional, Ganju, Vinod, additional, Green, Michael, additional, Patterson, Kevin, additional, Redfern, Andrew, additional, Richardson, Gary, additional, Ceric, Timur, additional, Gordana, Kecman, additional, Beato, Carlos Augusto, additional, Ferrari, Marcela, additional, Hegg, Roberto, additional, Helena, Vanessa, additional, Ismael, Gustavo Fernando, additional, Lessa, Alvaro Edson, additional, Mano, Max, additional, Morelle, Alessandra, additional, Nogueira, Jose Alberto, additional, Timcheva, Konstanta, additional, Tomova, Antoaneta, additional, Tsakova, Maya, additional, Zlatareva-Petrova, Ani, additional, Asselah, Jamil, additional, Assi, Hazem, additional, Brezden-Masley, Christine, additional, Chia, Stephen, additional, Freedman, Ori, additional, Harb, Mohammed, additional, Joy, Anil Abraham, additional, Kulkarni, Swati, additional, Prady, Catherine, additional, Gaete, Alejandro Andres Acevedo, additional, Matamala, Luis, additional, Torres, Roberto, additional, Yanez, Eduardo, additional, Franco, Sandra, additional, Urrego, Marcela, additional, Gugić, Damir, additional, Vrbanec, Damir, additional, Melichar, Bohuslav, additional, Prausová, Jana, additional, Vyzula, Rostislav, additional, Pilarte, Rafael Gutierrez, additional, León, María Isabel, additional, Muñoz, Rene, additional, Ramos, Glenda, additional, Azeem, Hamdy Abdel, additional, Aziz, Amr Abdel, additional, El Zawahry, Heba, additional, Osegueda, Finlander Rosales, additional, Alexandre, Jerome, additional, Artignan, Xavier, additional, Barletta, Hugues, additional, Beguier, Emmanuel, additional, Berdah, Jean-François, additional, Marty, Chantal Bernard, additional, Bollet, Marc, additional, Bourgeois, Hugues, additional, Bressac, Claude, additional, Burki, Franck, additional, Campone, Mario, additional, Coeffic, David, additional, Cojocarasu, Oana Zveltlana, additional, Dagada, Corinne, additional, Dalenc, Florence, additional, Del Piano, Francesco, additional, Desauw, Christophe, additional, Desmoulins, Isabelle, additional, Dohollou, Nadine, additional, Egreteau, Joelle, additional, Ferrero, Jean-Marc, additional, Foa, Cyril, additional, Garidi, Reda, additional, Gasnault, Laurent, additional, Gligorov, Joseph, additional, Guardiola, Emmanuel, additional, Hamizi, Salima, additional, Jarcau, Rosana, additional, Jacquin, Jean-Philippe, additional, Jaubert, Dominique, additional, Jolimoy, Geneviève, additional, Mineur, Hortense Laharie, additional, Largillier, Remy, additional, Leduc, Bernard, additional, Martin, Philippe, additional, Melis, Adrien, additional, Monge, Jeremy, additional, Moullet, Isabelle, additional, Mousseau, Mireille, additional, Nguyen, Suzanne, additional, Orfeuvre, Hubert, additional, Petit, Thierry, additional, Pivot, Xavier, additional, Priou, Frank, additional, Bach, Isabelle Sillet, additional, Simon, Helene, additional, Stefani, Laetitia, additional, Uwer, Lionel, additional, Youssef, Ali, additional, Aktas, Bahriye, additional, von der Assen, Albert, additional, Augustin, Doris, additional, Balser, Christina, additional, Bauer, Lelia-Eveline, additional, Bechtner, Christina, additional, Beyer, Greta, additional, Brucker, Cosima, additional, Bückner, Ute, additional, Busch, Steffi, additional, Christensen, Bernd, additional, Deryal, Mustafa, additional, Farrokh, Andre, additional, Faust, Elke, additional, Friedrichs, Kay, additional, Graf, Heiko, additional, Griesshammer, Martin, additional, Grischke, Eva-Maria, additional, Hänle, Claudia, additional, Heider, Andrea, additional, Henschen, Stephan, additional, Hesse, Tobias, additional, Jackisch, Christian, additional, Kisro, Jens, additional, Köhler, Andreas, additional, Kuemmel, Sherko, additional, Lampe, Dieter, additional, Lantzsch, Tilmann, additional, Latos, Kunibert, additional, Lex, Benno, additional, Liedtke, Cornelia, additional, Luedders, Doerte, additional, Maintz, Christoph, additional, Müller, Volkmar, additional, Overkamp, Friedrich, additional, Park-Simon, Tjoung-won, additional, Paul, Marion, additional, Prechtl, Anita, additional, Ringsdorf, Uta, additional, Runnebaum, Ingo, additional, Ruth, Sylvia, additional, Salat, Christoph, additional, Scheffen, Iris, additional, Schilling, Jörg, additional, Schmatloch, Sabine, additional, Schmidt, Marcus, additional, Schneeweiss, Andreas, additional, Schrader, Iris, additional, Seipelt, Gernot, additional, Simon, Elke, additional, Stefek, Andrea, additional, Stickeler, Elmar, additional, Thill, Marc, additional, Tio, Joke, additional, Tuczek, Anna, additional, Warm, Mathias, additional, Weigel, Michael, additional, Wischnik, Arthur, additional, Wojcinski, Sebastian, additional, Ziegler-Löhr, Katja, additional, Aravantinos, Gerasimos, additional, Ardavanis, Alexandros, additional, Fountzilas, George, additional, Gogas, Helen, additional, Kakolyris, Stylianos, additional, Mavroudis, Dimitris, additional, Papadimitriou, Christos, additional, Papandreou, Christos, additional, Papazisis, Konstantinos, additional, Castro, Hugo, additional, Hernandez-Monroy, Cesar Estuardo, additional, Ngan, Roger, additional, Yeo, Winnie, additional, Bittner, Nora, additional, Boer, Katalin, additional, Csejtei, Andras, additional, Horvath, Zsolt, additional, Kocsis, Judit, additional, Mangel, László Csaba, additional, Mezei, Klara, additional, Nagy, Zsuzsanna, additional, Szanto, Janos, additional, Atmakusuma, Djumhana, additional, Fadjari, Heri, additional, Kurnianda, Djohan, additional, Prayogo, Nugroho, additional, Tanggo, Eddie Herman, additional, Coate, Linda, additional, Hennessy, Bryan, additional, Kelly, Cathy, additional, Martin, Michael, additional, Nasim, Saira, additional, O'Connor, Miriam, additional, Aieta, Michele, additional, Allegrini, Giacomo, additional, Amadori, Dino, additional, Bidoli, Paolo, additional, Biti, Giampaolo, additional, Bordonaro, Roberto, additional, Bottini, Alberto, additional, Carterni, Giacomo, additional, Cavanna, Luigi, additional, Cazzaniga, Marina, additional, Cognetti, Francesco, additional, Contu, Antonio, additional, Cruciani, Giorgio, additional, Donadio, Michela, additional, Falcone, Alfredo, additional, Farci, Daniele, additional, Forcignanò, R. Chiara, additional, Frassoldati, Antonio, additional, Gaion, Fernando, additional, Gamucci, Teresa, additional, Giotta, Francesco, additional, de Laurentiis, Michele, additional, Livi, Lorenzo, additional, Lorusso, Vito, additional, Maiello, Evaristo, additional, Marchetti, Paolo, additional, Mariani, Gabriella, additional, Mion, Marta, additional, Moscetti, Luca, additional, Musolino, Antonino, additional, Pazzola, Antonio, additional, Pedrazzoli, Paolo, additional, Pigi, Andrea, additional, de Placido, Sabino, additional, Caremoli, Elena Rota, additional, Santoro, Armando, additional, Tienghi, Amelia, additional, Ahn, Jin-Seok, additional, Jung, Kyung Hae, additional, Lee, Keun Seok, additional, Lee, Soo Hyeon, additional, Seo, Jae Hong, additional, Sohn, Joo-Hyuk, additional, Cesas, Alvydas, additional, Juozaityte, Elona, additional, Cheah, Nellie Lay Chin, additional, Chong, Flora Li Tze, additional, Devi, Beena C.R., additional, Phua, Vincent, additional, Teoh, Darren, additional, Ching, Lee Wei, additional, Yusof, Mastura, additional, Corona, Jorge, additional, Dominguez, Adriana, additional, Mendoza, René Lazaro González, additional, Hernandez, Carlos Alberto, additional, Ramiro, Alejandro Juarez, additional, Santos, Juan Matos, additional, Espinosa, Paola Morales, additional, Villarreal Garza, Cynthia Mayte, additional, Errihani, Hassan, additional, Bakker, Sandra, additional, van den Berkmortel, Franchette, additional, Blaisse, R.J.B., additional, Huinink, Daan ten Bokkel, additional, van den Bosch, J., additional, Braun, J.J., additional, Dercksen, M.W., additional, Droogendijk, Helga, additional, Erdkamp, Frans, additional, Haringhuizen, Annebeth, additional, de Jongh, F.E., additional, Kok, T.C., additional, Los, Maartje, additional, Madretsma, Stanley, additional, Terwogt, Jetske M. Meerum, additional, van der Padt, Annemieke, additional, van Rossum-Schornagel, Quirine Clementine, additional, Smilde, T.J., additional, de Valk, Bart, additional, van der Velden, Annette, additional, van Warmerdam, Laurence, additional, van de Wouw, A.J., additional, North, Richard, additional, Kersten, Christian, additional, Mjaaland, Ingvild, additional, Wist, Erik, additional, Aziz, Zeba, additional, Masood, Nehal, additional, Rashid, Kamran, additional, Shah, Mazhar, additional, Alcedo, Juan Carlos, additional, Aleman, Diana, additional, Neciosup, Silvia, additional, Reategui, Rocio, additional, Valdiviezo, Natalia, additional, Vera, Luis, additional, Fernando, Gracieux, additional, Roque, Fernando, additional, Strebel, Heinrik Martin, additional, Krzemieniecki, Krzysztof, additional, Litwiniuk, Maria, additional, Mruk, Andrzej, additional, Pienkowski, Tadeusz, additional, Sawrycki, Piotr, additional, Slomian, Grzegorz, additional, Tomczak, Piotr, additional, Afonso, Noemia, additional, Cardoso, Fátima, additional, Damasceno, Margarida, additional, Nave, Monica, additional, Badulescu, Florinel, additional, Ciule, Larisa, additional, Curescu, Stefan, additional, Eniu, Alexandru, additional, Filip, Dumitru, additional, Grecea, Daniela, additional, Jinga, Dan-Corneliu, additional, Lungulescu, Dan, additional, Oprean, Cristina Marinela, additional, Stanculeanu, Dana Lucia, additional, Turdean, Maria, additional, Dvornichenko, Viktoria, additional, Emelyanov, Sergey, additional, Lichinitser, Mikhail, additional, Manikhas, Alexey, additional, Sakaeva, Dina, additional, Shirinkin, Vadim, additional, Stroyakovskiy, Daniil, additional, Abulkhair, Omalkhair, additional, Zekri, Jamal, additional, Filipovic, Sladjana, additional, Kovcin, Vladimir, additional, Nedovic, Jasmina, additional, Pesic, Jasna, additional, Vasovic, Suzana, additional, Ng, Raymond, additional, Bystricky, Branislav, additional, Leskova, Jaroslava, additional, Mardiak, Jozef, additional, Mišurová, Etela, additional, Wagnerova, Maria, additional, Takač, Iztok, additional, Demetriou, Georgia Savva, additional, Dreosti, Lydia, additional, Govender, Poovandren, additional, Jordaan, Johannes Petrus, additional, Veersamy, Petrosian, additional, Romero, Jose Luis Alonso, additional, Lopez, Norberto Batista, additional, Arias, Carmen Cañabate, additional, Chacon, Jose, additional, Aramburo, Antonio Fernandez, additional, Morales, Luis Antonio Fernandez, additional, Garcia, Mirta, additional, Estevez, Laura Garcia, additional, Garcia-Palomo Perez, Andres, additional, Garcia Saenz, Jose Angel, additional, Garcia Sanchis, Laura, additional, Cubells, Laia Garrigos, additional, Cortijo, Lucia Gonzalez, additional, Santiago, Santiago Gonzalez, additional, De Aranguiz, Blanca Hernando Fernandez, additional, Mañas, José Juan Illarramendi, additional, Gallego, Pedro Jimenez, additional, Cussac, Antonio Llombart, additional, Ferrandiz, Cristina Llorca, additional, Garrido, Maria Lomas, additional, Alvarez, Pilar Lopez, additional, Vega, Jose Manuel Lopez, additional, Del Prado, Purificacion Martinez, additional, Jañez, Noelia Martinez, additional, Murillo, Serafin Morales, additional, Rosales, Adolfo Murias, additional, Jaso, Laura Murillo, additional, Fernandez, Ignacio Pelaez, additional, Martorell, Antonia Perello, additional, Carrion, Ramon Perez, additional, Simon, Sonia Pernas, additional, Alcibar, Arrate Plazaola, additional, Lorenzo, Jose Ponce, additional, Garcia, Vanesa Quiroga, additional, Asensio, Teresa Ramon y Cajal, additional, Maicas, Maria Dolores Torregrosa, additional, Villanueva Silva, Maria Jose, additional, Killander, Fredrika, additional, Svensson, Jan Henry, additional, Fehr, Mathias, additional, Hauser, Nik, additional, Müller, Andreas, additional, Pagani, Olivia, additional, Passmann-Kegel, Heike, additional, Popescu, Razvan, additional, Rabaglio, Manuela, additional, Rauch, Daniel, additional, Schlatter, Christina, additional, Zaman, Khalil, additional, Chang, Tsai-Wang, additional, Huang, Chiun-Sheng, additional, Wang, Hwei-Chung, additional, Yu, Jyh-Cherng, additional, Bandidwattanawong, Chanyoot, additional, Maneechavakajorn, Jedzada, additional, Seetalarom, Kasan, additional, Dejthevaporn, Thitiya (Sirisinha), additional, Somwangprasert, Areewan, additional, Vongsaisuwon, Mawin, additional, Akbulut, Hakan, additional, Altundag, Kadri, additional, Arican, Ali, additional, Bozcuk, Hakan, additional, Eralp, Yesim, additional, Idris, Mohamed, additional, Isikdogan, Abdurrahman, additional, Senol, Coskun Hasan, additional, Sevinc, Alper, additional, Uygun, Kazim, additional, Yucel, Eftal, additional, Yucel, Idris, additional, Yumuk, Fulden, additional, Shparyk, Yaroslav, additional, Voitko, Nataliia, additional, Jaloudi, Mohammed, additional, Adams, Jocelyn, additional, Agrawal, Rajiv, additional, Ahmed, Samreen, additional, Alhasso, Abdulla, additional, Allerton, Rozenn, additional, Anwar, Suhail, additional, Archer, Caroline, additional, Ashford, Richard, additional, Barraclough, Lisa, additional, Bertelli, Gianfilippo, additional, Bishop, Jill, additional, Branson, Tony, additional, Butt, Mohammed, additional, Chakrabarti, Amit, additional, Chakraborti, Prabir, additional, Churn, Mark, additional, Crowley, Clare, additional, Davis, Ruth, additional, Dhadda, Amandeep, additional, Eldeeb, Hany, additional, Fraser, Judith, additional, Hall, Julia, additional, Hickish, Tamas, additional, Hogg, Martin, additional, Howe, Theresa, additional, Joffe, Jonathan, additional, Kelleher, Muireann, additional, Kelly, Stephen, additional, Kendall, Anne, additional, Kristeleit, Hartmut, additional, Lumsden, Graeme, additional, Macmillan, Craig, additional, MacPherson, Iain, additional, Malik, Zafar, additional, Mithal, Natasha, additional, Neal, Anthony, additional, Panwar, Udaiveer, additional, Proctor, Andrew, additional, Proctor, Steven John, additional, Raj, Sanjay, additional, Rehman, Shazza, additional, Sandri, Ines, additional, Scatchard, Kate, additional, Sherwin, Elizabeth, additional, Sims, Eliot, additional, Singer, Julian, additional, Smith, Sarah, additional, Tahir, Saad, additional, Taylor, Wendy, additional, Tsalic, Medy, additional, Verrill, Mark, additional, Wardley, Andrew, additional, Waters, Simon, additional, Wheatley, Duncan, additional, Wright, Kathryn, additional, Yuille, Frances, additional, Alonso, Isabel, additional, Artagaveytia, Nora, additional, Rodriguez, Robinson, additional, Arbona, Esther, additional, Garcia, Yuraima, additional, Lion, Lorena, additional, Marcano, Dalila, additional, and Van Thuan, Tran, additional
- Published
- 2017
- Full Text
- View/download PDF
44. Evaluating the addition of bevacizumab (Bev) to endocrine therapy as first-line treatment for hormone-receptor positive (HR+)/HER2-negative advanced breast cancer (ABC): Pooled-analysis from the LEA (GEICAM/2006-11_GBG51) and CALGB 40503 (Alliance) trials.
- Author
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Martin, Miguel, primary, Loibl, Sibylle, additional, Hyslop, Terry, additional, de la Haba-Rodriguez, Juan, additional, Aktas, Bahriye, additional, Cirrincione, Constance, additional, Carrasco, Eva Maria, additional, Mehta, Keyur, additional, Barry, William Thomas, additional, Morales, Serafin, additional, Carey, Lisa A., additional, Garcia Saenz, Jose Angel, additional, Partridge, Ann, additional, Martinez, Noelia, additional, Hahn, Olwen Mary, additional, Winer, Eric P., additional, Guerrero, Angel, additional, Hudis, Cliff, additional, Casas, Maribel, additional, and Dickler, Maura N., additional
- Published
- 2017
- Full Text
- View/download PDF
45. A phase 2 study of investigational TORC1/2 inhibitor TAK-228 with fulvestrant in women with ER+/HER2–advanced or metastatic breast cancer (mBC) that has progressed during or after aromatase inhibitor (AI) therapy.
- Author
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Garcia Saenz, Jose Angel, primary, Ramos Vazquez, Manuel, additional, Martin, Miguel, additional, Ruiz, Amparo, additional, Morales, Serafin, additional, Bermejo, Begona, additional, Ruiz, Isabel, additional, Cubedo, Ricardo, additional, Merino, Luis De la Cruz, additional, Anton, Antonio, additional, Carrasco, Eva Maria, additional, Kneissl, Michelle, additional, Zohren, Fabian, additional, and Martinez, Noelia, additional
- Published
- 2017
- Full Text
- View/download PDF
46. Nab-Paclitaxel in Metastatic Breast Cancer: Defining the Best Patient Profile
- Author
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Gonzzlez-Martin, Antonio, primary, Alba, Emilio, additional, Ciruelos, Eva, additional, Cortes, Javier, additional, Llombart, Antonio, additional, Lluch, Ana, additional, Andres, Raquel, additional, Alvarez, Isabel, additional, Manuel Aramendia, Jose, additional, Ayala de la Pena, Francisco, additional, Barnadas, Agusti, additional, Batista, Norberto, additional, Calvo, Lourdes, additional, Galve, Elena, additional, Garcia-Palomo, Andres, additional, Angel Garcia-Saenz, Jose, additional, de la Haba, Juan, additional, Lopez, Rafael, additional, Lopez-Vivanco, Guillermo, additional, Martinez-Janez, Noelia, additional, Martinez de Duenas, Eduardo, additional, Plazaola, Arrate, additional, Rodriguez-Lescure, Alvaro, additional, Ruiz, Manuel, additional, Sanchez-Rovira, Pedro, additional, Santaballa, Ana, additional, Angel Segui, Miguel, additional, Tusquets, Ignasi, additional, Zamora, Pilar, additional, and Martin, Miguel, additional
- Published
- 2016
- Full Text
- View/download PDF
47. Cobimetinib (C) + paclitaxel (P) as first-line treatment in patients (pts) with advanced triple-negative breast cancer (TNBC): Updated results and biomarker data from the phase 2 COLET study.
- Author
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Brufsky, Adam, primary, Kim, Sung-Bae, additional, Velu, Thierry J., additional, Garcia Saenz, Jose Angel, additional, Tan-Chiu, Elizabeth, additional, Sohn, Joohyuk, additional, Dirix, Luc Yves, additional, Vanasek, Jaroslav, additional, Borms, Marleen V., additional, Mingorance, J. Ignacio Delgado, additional, Liu, Mei-Ching, additional, Moezi, Mehdi M., additional, Kozloff, Mark, additional, Sparano, Joseph A., additional, Hsu, Jessie J., additional, Wongchenko, Matthew, additional, Simmons, Brian P., additional, McNally, V. A., additional, and Miles, David, additional
- Published
- 2016
- Full Text
- View/download PDF
48. Relationship of germline polymorphisms to docetaxel toxicity in the ROSE/TRIO-012 trial.
- Author
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Damaraju, Sambasivarao, primary, Gorbunova, Vera, additional, Gelmon, Karen A., additional, Garcia Saenz, Jose Angel, additional, Morales, Serafin, additional, Abigerges, Dany Youssef, additional, Canon, Jean-Luc, additional, Lifirenko, Igor, additional, Cohen, Graham Lawrence, additional, Jerusalem, Guy Heinrich Maria, additional, Thireau, Francois, additional, Fresco, Rodrigo, additional, Houé, Vincent, additional, Press, Michael F., additional, Narasimhan, Ashok, additional, and Mackey, John Robert, additional
- Published
- 2015
- Full Text
- View/download PDF
49. Concordance between immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) for HER2 determination and correlation with clinical and pathological data.
- Author
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Callata-Carhuapoma, Hector Randhall, primary, Sotelo Lezama, Miguel, additional, Cabezas, Santiago, additional, Garcia Saenz, Jose Angel, additional, Moreno, Fernando, additional, Serrano, Gloria, additional, Sanz, Julian, additional, Gonzalez-Larriba, Jose-Luis, additional, Acosta Eyzaguirre, Daniel, additional, and Diaz-Rubio, Eduardo, additional
- Published
- 2015
- Full Text
- View/download PDF
50. Abstract P4-02-10: Detection of H1047R and E545K PIK3CA mutations from peripheral blood in ER positive breast cancer patients
- Author
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Garcia-Saenz, Jose Angel, primary, Acosta, Daniel, additional, Moreno, Fernando, additional, Ayllon, Paticia, additional, Sotelo, Miguel, additional, Caldes, Trinidad, additional, Diaz-Rubio, Eduardo, additional, and Romero, Atocha, additional
- Published
- 2015
- Full Text
- View/download PDF
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