Search

Abstract: Unprincipled use of antibiotics has led to antimicrobial resistance (AMR) against mostlyavailable compounds, and has now become a major cause of concern for the scientific community.However, in the past decade, green synthesized silver nanoparticles (AgNPs) have received greaterattention for the development of newer therapies as antimicrobials by virtue of their unique physico-chemical properties. Unlike traditional antibiotics, AgNPs exert their action by acting on multiplemechanisms, which make them potential candidates against AMR. Green synthesis of AgNPsusing various medicinal plants has demonstrated a broader spectrum of action against several microbesin a number of attempts. The present paper provides an insight into the scientific studiesthat have elucidated the positive role of plant extracts/phytochemicals during the green synthesis ofAgNPs and their future perspectives. The studies conducted so far seem promising; still, a few factorslike the precise mechanism of action of AgNPs, their synergistic interaction with biomolecules,and industrial scalability, need to be explored further till effective drug development usinggreen synthesized AgNPs in healthcare systems against AMR is established.

Nasal intubation is an obvious choice for temporomandibular joint (TMJ) ankylosis surgery (Fig.1) (1). Adequate surgical access and better fixation makes RAE (Ring-Adair-Elwin) nasal tube a preferred choice (2). Conventional lighted stylet does not support RAE intubation due to short length of its stylet (Fig.2). Our innovative lighted stylet can easily help in RAE tube insertion in these cases (Fig.3) (3). It is simple to make and can be easily assembled from materials commonly available in the operating room. (3), Case Report A 22 year old female patient was admitted to our hospital with temporomandibular joint (TMJ) ankylosis and posted for gap arthroplasty (Fig.1). Preoperative investigations revealed haemoglobin 11.3 gm%, [...]

Table of Contents Abstract Introduction Discussion References Abstract Central venous catheter (CVC) insertion may be associated with many life threatening complications. Here, we are reporting a case of unusual placement [...]

Table of Contents Abstract Introduction Case History Discussion References Abstract Tracheal intubation by direct laryngoscopy remains the technique of choice to achieve to control of airway. However, alternative techniques are [...]

Background: Boswellic acids (BAs) are extracted from oleo gum of Boswellia serrata and are utilized as potential anti-inflammatory, hypolipidemic, immunomodulatory and antitumor specialists. The present examination was meant to assess KBA and AKBA in Boswellia serrata separate by High-Performance Thin Layer Chromatography (HPTLC). Methods: The separation of bioactive compounds was performed utilizing mobile phase glacial acetic acid, n-hexane, ethyl acetate and toluene (0.3: 1: 8: 2) (v/v/v/v) and distinguished at wavelength 254 nm. The technique was approved for linearity, precision, accuracy, limit of detection (LOD), limit of quantification (LOQ), and so forth by International Conference on Harmonization guidelines. Results: The calibration range was observed to be 2- 14 μg/band for both the bioactive compounds. KBA was isolated with an Rf estimation of 0.39 ± 0.02 and AKBA with an Rf estimation of 0.42 ± 0.02. The accuracy was seen to be as high as 99.17% and 97.42 for KBA and KBA, respectively. The percentage RSD value for intra-day and between day varieties was under 2%. The system indicated high affectability and specificity. Conclusion: The developed HPTLC method was simple, precise, robust, specific, rapid, and costeffective and could be used for quality control analysis and quantification of KBA and AKBA in different herbal formulations containing the plant species.