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In 2015 zijn de Gezondheidsfondsen voor Rookvrij gestart met een initiatief om sportverenigingen in Nederland rookvrij te maken. Veel kinderen komen op sportverenigingen waar vaak nog buiten wordt gerookt, bijvoorbeeld langs de lijn. Terwijl zien roken, doet roken. Een rookvrije sportvereniging biedt het goede voorbeeld. Het initiatief ‘Rookvrije Sportverenigingen’ stimuleert verenigingen om een rookvrij beleid in te voeren en geeft hen handvaten hoe dit te realiseren. Het initiatief bestaat uit een informatiepakket en verenigingen kunnen begeleid worden door adviseurs, zoals een Team:Fit coach, buurtsportcoach of GGD medewerker. Ook zijn er fysieke promotiematerialen zoals borden beschikbaar om het rookvrij beleid uit te dragen. In 2019 hebben het Amsterdam UMC en Tranzo, Tilburg University een rookvrij beleid op 16 sportverenigingen onderzocht. In deze factsheet worden resultaten en tips gepresenteerd, gebaseerd op interviews met 87 vrijwilligers en groepsgesprekken met 180 jongeren.

BACKGROUND: Typical practice is to transfuse group-specific plasma units; however, there are situations where group AB plasma (universal donor) is issued to group A, B, or O recipients. If demand for group AB plasma exceeds collections, there is potential for shortage. This project explored the patterns of group AB plasma utilization at hospitals around the world. STUDY DESIGN AND METHODS: The study had two phases: a survey that inquired about hospital group AB plasma inventory, policies, and transfusion practices and a retrospective review of 2014 calendar year data where participants submitted information on plasma disposition including ABO group of unit and recipient, transfusion location, and select indications. Recruitment occurred through snowball sampling. Descriptive analyseswere performed. RESULTS: Survey data were received from 25 centers across 10 countries; ofthose, 15participants contributed to the data collection component. These 15 centers transfused a total of 43,369 AB plasma units during the study period. Only 1496 of 5541 (27%) group ABplasma unitswere transfused to group AB recipients. Transfusion policies, practices, and patterns werevariable across sites. CONCLUSION: Group AB plasma units are frequently transfused to non-AB recipients. Whether transfusing 73% of group AB plasma units to non-AB recipients is the ideal inventory management strategy remains to be determined.

Background: Transfusion of group O blood to non‐O recipients, or transfusion of D- blood to D+ recipients, can result in shortages of group O or D- blood, respectively. This study investigated RBC utilization patterns at hospitals around the world and explored the context and policies that guide ABO blood group and D type selection practices. Study design and methods: This was a retrospective study on transfusion data from the 2013 calendar year. This study included a survey component that asked about hospital RBC selection and transfusion practices and a data collection component where participants submitted information on RBC unit disposition including blood group and D type of unit and recipient. Units administered to recipients of unknown ABO or D group were excluded. Results: Thirty‐eight hospitals in 11 countries responded to the survey, 30 of which provided specific RBC unit disposition data. Overall, 11.1% (21,235/191,397) of group O units were transfused to non‐O recipients; 22.6% (8777/38,911) of group O D- RBC units were transfused to O D+ recipients, and 43.2% (16,800/38,911) of group O D- RBC units were transfused to recipients that were not group O D-. Disposition of units and hospital transfusion policy varied within and across hospitals of different sizes, with transfusion of group O D- units to non‐group O D- patients ranging from 0% to 33%. Conclusion: A significant proportion of group O and D- RBC units were transfused to compatible, nonidentical recipients, although the frequency of this practice varied across sites.

Wir berichten über ein 14 Jahre altes Mädchen mit Immunthrombozytopenie, welches bei einer Plättchenzahl von 37 G/l eine intracranielle Blutung erlitt. Eine Spezifität nachgewiesener plättchenassoziierter Antikörper gegen den Glykoproteinkomplex IIa/IIIb deutete[for full text, please go to the a.m. URL], 60. Jahrestagung der Norddeutschen Gesellschaft für Kinder- und Jugendmedizin

Panic disorder like other neuropsychiatric disorders is believed to be caused by multiple psychosocial and biological factors. Several lines of evidence point to a role for the peptide neurotransmitter cholecystokinin in the pathogenesis of panic disorder. We therefore determined the allele and genotype frequencies of a single nucleotide polymorphism in the CCK gene (-36CT) and one CT repeat polymorphism in the CCK-B-receptor gene in a German panic disorder sample (n = 115 for CCK gene polymorphism, n = 111 for CCK-B-receptor polymorphism) and compared them with gender and age matched controls. The length of the polymorphic CT repeat alleles varies between 146 bp and 180 bp. We first analysed the results by a permutation test which provided evidence for heterogeneity between patients and controls (p=0.002). We then analysed the data as a di-allelic polymorphism with a short (146-162bp) and a long (164-180bp) allele and as a tetra-allelic polymorphism with 4 alleles (146-154bp, 156-162bp, 164-170bp, 172-180bp). In the di-allelic analysis as well as in the tetra-allelic analysis there was an excess of the longer allele (p = 0.001) or the two longer alleles (p = 0.041) respectively in patients with panic disorder. No difference between groups was observed for the -36CT polymorphism. Our findings are consistent with the notion that genetic variation in the CCK neurotransmitter system contributes to the pathogenesis of panic disorder.