Search

Your search keyword '"Garshasbi, Saba"' showing total 22 results
Start Over Author "Garshasbi, Saba"
22 results on '"Garshasbi, Saba"'

8. SARS-CoV-2 Infection in Iranian People Living with Human Immunodeficiency Virus-1 Infection

Author

Garshasbi, Saba, primary, Bokharaei-Salim, Farah, additional, Khanaliha, Khadijeh, additional, Kiani, Seyed Jalal, additional, Kalantari, Saeed, additional, Jamshidi Makiani, Mahin, additional, Marjani, Arezoo, additional, Dehghani-Dehej, Farzaneh, additional, Babaei, Roghayeh, additional, Sadeghi, Mohsen, additional, and Abbassi-Kolli, Mohammad, additional

Published
2022
Full Text
View/download PDF

9. Evaluation of the Expression Pattern of 4 microRNAs and their Correlation with Cellular/viral Factors in PBMCs of Long Term Non-progressors and HIV Infected Naïve Individuals

Author

Bokharaei-Salim, Farah, primary, Jamshidi, Sogol, additional, Nahand, Javid Sadri, additional, Monavari, Seyed Hamidreza, additional, Moghoofei, Mohsen, additional, Garshasbi, Saba, additional, Kalantari, Saeed, additional, Esghaei, Maryam, additional, and Mirzaei, Hamed, additional

Published
2022
Full Text
View/download PDF

12. Acute and post-acute phase of COVID-19: Analyzing expression patterns of miRNA-29a-3p, 146a-3p, 155-5p, and let-7b-3p in PBMC

Author

Donyavi, Tahereh, primary, Bokharaei-Salim, Farah, additional, Baghi, Hossein Bannazadeh, additional, Khanaliha, Khadijeh, additional, Alaei Janat-Makan, Mahrokh, additional, Karimi, Bahareh, additional, Sadri Nahand, Javid, additional, Mirzaei, Hamed, additional, Khatami, AliReza, additional, Garshasbi, Saba, additional, Khoshmirsafa, Majid, additional, and Jalal Kiani, Seyed, additional

Published
2021
Full Text
View/download PDF

16. Evaluation of CCR5‐Δ32 mutation among individuals with high risk behaviors, neonates born to HIV‐1 infected mothers, HIV‐1 infected individuals, and healthy people in an Iranian population

Author

Donyavi, Tahereh, primary, Bokharaei‐Salim, Farah, additional, Nahand, Javid Sadri, additional, Garshasbi, Saba, additional, Esghaei, Maryam, additional, Sadeghi, Mohsen, additional, Jamshidi, Sogol, additional, and Khanaliha, Khadijeh, additional

Published
2020
Full Text
View/download PDF

18. Evaluation of the Expression Pattern of 4 microRNAs and their Correlationwith Cellular/viral Factors in PBMCs of Long Term Non-progressorsand HIV Infected Naïve Individuals

Author

Jamshidi, Sogol, Bokharaei-Salim, Farah, Nahand, Javid Sadri, Monavari, Seyed Hamidreza, Moghoofei, Mohsen, Garshasbi, Saba, Kalantari, Saeed, Esghaei, Maryam, and Mirzaei, Hamed

Abstract

Background: Long-term non-progressors (LTNPs) are small subsets of HIV-infectedsubjects that can control HIV-1 replication for several years without receiving ART. The exactmechanism of HIV-1 suppression has not yet been completely elucidated. Although the modulatoryrole of microRNAs (miRNAs) in HIV-1 replication has been reported, their importance in LTNPsis unclear. Objective: The aim of this cross-sectional study was to assess the expression pattern of miR-27b,-29, -150, and -221, as well as their relationship with CD4+ T-cell count, HIV-1 viral load, and nefgene expression in peripheral blood mononuclear cells (PBMCs) of untreated viremic patients andin LTNPs. Methods: MiRNAs expression levels were evaluated with real-time PCR assay using RNA isolatedfrom PBMCs of LTNPs, HIV-1 infected naive patients, and healthy people. Moreover, CD4 T-cellcount, HIV viral load, and nef gene expression were assessed. Results: The expression level of all miRNAs significantly decreased in the HIV-1 patient groupcompared to the control group, while the expression pattern of miRNAs in the LNTPs group wassimilar to that in the healthy subject group. In addition, there were significant correlations betweensome miRNA expression with viral load, CD4+ T-cell count, and nef gene expression. Conclusion: The significant similarity and difference of the miRNA expression pattern betweenLNTPs and healthy individuals as well as between elite controllers and HIV-infected patients, respectively,showed that these miRNAs could be used as diagnostic biomarkers. Further, positiveand negative correlations between miRNAs expression and viral/cellular factors could justify therole of these miRNAs in HIV-1 disease monitoring.

Published
2022
Full Text
View/download PDF

20. microRNAs 29, 150, 155, 223 level and their relation to viral and immunological markers in HIV-1 infected naive patients

Author

Moghoofei, Mohsen, primary, Bokharaei-Salim, Farah, additional, Esghaei, Maryam, additional, Keyvani, Hossein, additional, Honardoost, Maryam, additional, Mostafaei, Shayan, additional, Ghasemi, Amir, additional, Tavakoli, Ahmad, additional, Javanmard, Davod, additional, Babaei, Farhad, additional, Garshasbi, Saba, additional, and Monavari, Seyed Hamidreza, additional

Published
2018
Full Text
View/download PDF

21. Presence of different hepatitis C virus genotypes in plasma and peripheral blood mononuclear cell samples of Iranian patients with HIV infection

Author

Dehghani-Dehej, Farzaneh, primary, Sarvari, Jamal, additional, Esghaei, Maryam, additional, Hosseini, Seyed Y., additional, Garshasbi, Saba, additional, Kalantari, Saeed, additional, Monavari, Seyed H., additional, Fakhim, Atousa, additional, Keyvani, Hossein, additional, and Bokharaei-Salim, Farah, additional

Published
2018
Full Text
View/download PDF

22. Evaluation of the Expression Pattern of 4 microRNAs and their Correlation with Cellular/viral Factors in PBMCs of Long Term Non-progressors and HIV Infected Naïve Individuals.

Author

Jamshidi S, Bokharaei-Salim F, Nahand JS, Monavari SH, Moghoofei M, Garshasbi S, Kalantari S, Esghaei M, and Mirzaei H

Subjects
CD4 Lymphocyte Count, Cross-Sectional Studies, Humans, Leukocytes, Mononuclear, Viral Load, HIV Infections, HIV-1 genetics, MicroRNAs genetics, MicroRNAs metabolism
Abstract

Background: Long-term non-progressors (LTNPs) are small subsets of HIV-infected subjects that can control HIV-1 replication for several years without receiving ART. The exact mechanism of HIV-1 suppression has not yet been completely elucidated. Although the modulatory role of microRNAs (miRNAs) in HIV-1 replication has been reported, their importance in LTNPs is unclear., Objective: The aim of this cross-sectional study was to assess the expression pattern of miR-27b, -29, -150, and -221, as well as their relationship with CD4+ T-cell count, HIV-1 viral load, and nef gene expression in peripheral blood mononuclear cells (PBMCs) of untreated viremic patients and in LTNPs., Methods: MiRNAs expression levels were evaluated with real-time PCR assay using RNA isolated from PBMCs of LTNPs, HIV-1 infected naive patients, and healthy people. Moreover, CD4 T-cell count, HIV viral load, and nef gene expression were assessed., Results: The expression level of all miRNAs significantly decreased in the HIV-1 patient group compared to the control group, while the expression pattern of miRNAs in the LNTPs group was similar to that in the healthy subject group. In addition, there were significant correlations between some miRNA expression with viral load, CD4+ T-cell count, and nef gene expression., Conclusion: The significant similarity and difference of the miRNA expression pattern between LNTPs and healthy individuals as well as between elite controllers and HIV-infected patients, respectively, showed that these miRNAs could be used as diagnostic biomarkers. Further, positive and negative correlations between miRNAs expression and viral/cellular factors could justify the role of these miRNAs in HIV-1 disease monitoring., (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results