45 results on '"Gary, Bernard D."'
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2. Trisubstituted and tetrasubstituted pyrazolines as a novel class of cell-growth inhibitors in tumor cells with wild type p53
3. Synthesis of some dihydropyrimidine-based compounds bearing pyrazoline moiety and evaluation of their antiproliferative activity
4. Exploring the PDE5 H-pocket by ensemble docking and structure-based design and synthesis of novel β-carboline derivatives
5. Novel non-cyclooxygenase inhibitory derivatives of naproxen for colorectal cancer chemoprevention
6. Synthesis, molecular modeling and biological evaluation of novel tadalafil analogues as phosphodiesterase 5 and colon tumor cell growth inhibitors, new stereochemical perspective
7. Discovery of colon tumor cell growth inhibitory agents through a combinatorial approach
8. Design, synthesis and biological evaluation of novel pyridine derivatives as anticancer agents and phosphodiesterase 3 inhibitors
9. Design and Synthesis of Substituted Pyridazinone-1-Acetylhydrazones as Novel Phosphodiesterase 4 Inhibitors
10. Abstract B39: A novel series of substituted indene derivatives that potently and selectively inhibit growth of tumor cells harboring mutant Ras
11. Abstract 2322: β-catenin-dependent TCF/LEF transcriptional regulation of phosphodiesterase expression in colon cancer cells
12. Novel Quinazolin-4(3H)-one/Schiff Base Hybrids as Antiproliferative and Phosphodiesterase 4 Inhibitors: Design, Synthesis, and Docking Studies
13. Panepoxydone Targets NF-kB and FOXM1 to Inhibit Proliferation, Induce Apoptosis and Reverse Epithelial to Mesenchymal Transition in Breast Cancer
14. ChemInform Abstract: Synthesis of Some Dihydropyrimidine‐Based Compounds Bearing Pyrazoline Moiety and Evaluation of Their Antiproliferative Activity.
15. Abstract C182: Phosphodiesterase 10: A novel cancer target.
16. Sulindac Selectively Inhibits Colon Tumor Cell Growth by Activating the cGMP/PKG Pathway to Suppress Wnt/β-Catenin Signaling
17. ChemInform Abstract: Design of Novel β-Carboline Derivatives with Pendant 5-Bromothienyl and Their Evaluation as Phosphodiesterase-5 Inhibitors.
18. Abstract 3659: Next generation sulindac.
19. Abstract 5571: Antitumor activity of a novel natural therapeutic agent against triple negative breast cancer.
20. Design of Novel β-Carboline Derivatives with Pendant 5-Bromothienyl and Their Evaluation as Phosphodiesterase-5 Inhibitors
21. A Novel Sulindac Derivative that Potently Suppresses Colon Tumor Cell Growth by Inhibiting cGMP Phosphodiesterase and β-Catenin Transcriptional Activity
22. Abstract 570: Breast cancer chemopreventive activity of a novel amide derivative of sulindac involves inhibition of PDE5, activation of PKG, and attenuation of Wnt/β-catenin signaling
23. Inhibition of PDE5 by Sulindac Sulfide Selectively Induces Apoptosis and Attenuates Oncogenic Wnt/β-Catenin–Mediated Transcription in Human Breast Tumor Cells
24. ChemInform Abstract: Design, Synthesis and Structure-Activity Relationship of Functionalized Tetrahydro-β-carboline Derivatives as Novel PDE5 Inhibitors.
25. Abstract 1865: Colon cancer chemopreventive properties of a non-cyclooxygenase inhibitory amide derivative of sulindac
26. Abstract 837: Novel sulindac derivatives that inhibit colon cancer growth by a COX independent mechanism involving PDE5 inhibition and the suppression of nuclear β-catenin levels
27. Synthesis and Molecular Modeling of Novel Tetrahydro-β-carboline Derivatives with Phosphodiesterase 5 Inhibitory and Anticancer Properties
28. Design, Synthesis and Structure-Activity Relationship of Functionalized Tetrahydro-β-carboline Derivatives as Novel PDE5 Inhibitors
29. Colon Tumor Cell Growth–Inhibitory Activity of Sulindac Sulfide and Other Nonsteroidal Anti-Inflammatory Drugs Is Associated with Phosphodiesterase 5 Inhibition
30. ChemInform Abstract: Synthesis, Molecular Modeling and Biological Evaluation of Novel Tadalafil Analogues as Phosphodiesterase 5 and Colon Tumor Cell Growth Inhibitors, New Stereochemical Perspective.
31. A Novel Sulindac Derivative Lacking Cyclooxygenase-Inhibitory Activities Suppresses Carcinogenesis in the Transgenic Adenocarcinoma of Mouse Prostate Model
32. NSAIDs: Old Drugs Reveal New Anticancer Targets
33. ChemInform Abstract: Discovery of Colon Tumor Cell Growth Inhibitory Agents Through a Combinatorial Approach.
34. ChemInform Abstract: Synthesis of Novel Tadalafil Analogues and Their Evaluation as Phosphodiesterase Inhibitors and Anticancer Agents.
35. Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G
36. A Novel Sulindac Derivative That Does Not Inhibit Cyclooxygenases but Potently Inhibits Colon Tumor Cell Growth and Induces Apoptosis with Antitumor Activity
37. Sulindac sulfide selectively increases sensitivity of ABCC1 expressing tumor cells to doxorubicin and glutathione depletion.
38. Design and Synthesis of Substituted Pyridazinone-1-Acetylhydrazones as Novel Phosphodiesterase 4 Inhibitors.
39. Novel Quinazolin-4(3 H)-one/Schiff Base Hybrids as Antiproliferative and Phosphodiesterase 4 Inhibitors: Design, Synthesis, and Docking Studies.
40. Design, Synthesis and Structure-Activity Relationship of Functionalized Tetrahydro-.
41. Mining ZINC Database to Discover Potential Phosphodiesterase 9 Inhibitors Using Structure-Based Drug Design Approach.
42. Four-component synthesis of 1,2-dihydropyridine derivatives and their evaluation as anticancer agents.
43. Synthesis and molecular modeling of novel tetrahydro-β-carboline derivatives with phosphodiesterase 5 inhibitory and anticancer properties.
44. A novel access to arylated and heteroarylated beta-carboline based PDE5 inhibitors.
45. Synthesis of novel tadalafil analogues and their evaluation as phosphodiesterase inhibitors and anticancer agents.
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