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7. Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials

Author

Cole, Abosede O, Gerstenblith, Adam T, Kotagiri, Ajay, Edwards, Albert O, Zambrano, Alberto D, Eaton, Alexander M, Rubowitz, Alexander, Lyon, Alice T, Chiang, Allen, Ho, Allen, Hu, Allen Y, Guerami, Amir H, Dessouki, Amr L, de Carvalho, André Corrêa Maia, Emanuelli, Andrés, Chang, Andrew A, Antoszyk, Andrew N, Francone, Anibal Andrés, Prasad, Anita, Wolf, Armin, Khanani, Arshad M, Abbey, Ashkan Michael, Moulana, Asma, Wihelm, Barbara, Sikorski, Bartosz L, Kuppermann, Baruch D, Wolff, Benjamin, Jewart, Brian H, Do, Brian K, Chan-Kai, Brian T, Mein, Calvin, Hoyng, Carel B, Awh, Carl C, Regillio, Carl, Zeolite, Carlos, Baumal, Caroline R, Creuzot-Garcher, Catherine, Maury, Catherine Français, Wykoff, Charles C, Newell, Charles K, Jhaveri, Chirag, Lohmann, Chris P, Dinah, Christiana B, Ma, Colin, Crawford, Courtney, Parke, D Wilkin, Lavinsky, Daniel, Roth, Daniel, Pieramici, Dante J, Moshfeghi, Darius M, Levin, Darrin, Saperstein, David A, Brown, David, Gaucher, David, Lally, David R, Liao, David S, Brown, David Warren, Goldstein, Debra, Marcus, Dennis, Chan, Derek G, Dhoot, Dilsher, Tacite, Domingo, Zalewski, Dominik, Espana, Edgar M, Lad, Eleonora M, Souied, Eric H, Suan, Eric P, Eting, Eva, Sola, Federico Furno, de Bats, Flore, Bandello, Francesco, Gómez-Ulla, Francisco, Devin, François, Holz, Frank G, Chen, Fred K, Makkouk, Fuad, Dyer, Gawain, Spital, George, Staurenghi, Giovanni, Stoller, Glenn, Cousins, Gwen, Salehi-Had, Hani, Agostini, Hansjürgen, Eleftheriadis, Haralabos, Weiss, Harold, Sultan, Harris C, Massé, Hélène, Pearce, Ian, Dias, Indra, Barbazetto, Irene, Rosenblatt, Irit, Suñer, Ivan J, Kovach, Jaclyn L, Kaluzny, Jakub, Borthwick, James, Howard, James G, Wong, James, Ernest, Jan, Němčanský, Jan, Ysasaga, Jason Edward, Handza, Jason M, Moreno, Javier Antonio Montero, Korobelnik, Jean-François, Heier, Jeffrey S, Arnold, Jennifer J, Brown, Jeremiah, Bafalluy, Joaquin, Pearlman, Joel, Pitcher, John D, Kitchens, John, Carlson, John P, Gilhotra, Jolly, Fein, Jordana, Monés, Jordi M, Luna, José Domingo, Moreno, José María Ruiz, Coney, Joseph M, Sallum, Juliana Maria Ferraz, Olsen, Karl R, Blobner, Katharina, Macoul, Katherine A, Oh, Kean T, Malik, Khurram Javed, Hattenbach, Lars-Olof, Kodjikian, Laurent, Neto, Laurentino Biccas, Singerman, Lawrence J, Altay, Lebriz, Sheck, Leo-H, Feiner, Leonard, Harris, Lindsey D, Chishold, Lionel D, Rao, Llewelyn J, Nehemy, Márcio Bittar, Elizalde, Maria Jose Capella, Gamulescu, Maria-Andreea, Saravia, Mario J, Johnson, Mark W, McKibbin, Martin, Maccumber, Mathew, Vidosevich, Matko, Ohr, Matthew P, Samuel, Michael A, Singer, Michael A, Cassell, Michael, Dollin, Michael, Elman, Michael J, Ip, Michael S, Goldstein, Michaella, Busquets, Miguel, Mititelu, Mihai, Shah, Milan, Veith, Miroslav, Fineman, Mitchell, Varano, Monica, Christmas, Nancy, Steinle, Nathan C, Chaudhry, Nauman, Chinskey, Nicholas D, Eter, Nicole, London, Nikolas J S, Mathalone, Nurit, Schlottmann, Patricio G, Coady, Patrick, Higgins, Patrick M, Raskauskas, Paul A, Yates, Paul A, Bernstein, Paul, Mitchell, Paul, Monsour, Paul, Raphaelian, Paul V, Stanga, Paulo E, Stodulka, Pavel, Issa, Peter Charbel, Pavan, Peter, Ferrone, Phil J, Oleksy, Piotr, Abraham, Prema, Mruthyunjaya, Prithvi, Nguyen, Quan Dong, Reddy, Rahul K, Khurana, Rahul N, Tuli, Raman, Tadayoni, Ramin, Katz, Randy Steven, Arora, Rashi, Schlingemann, Reinier O, Rosen, Richard B, Gale, Richard, Scartozzi, Richard, Isernharge, Ricky, Singh, Rishi P, Stoltz, Robert A, Avery, Robert L, Wirthlin, Robert S, Guymer, Robyn, Goldberg, Roger A, Frenkel, Ronald, Belfort, Rubens Jr, Mohand-Said, Saddek, Grisanti, Salvatore, Razavi, Sam, Fraser-Bell, Samantha, Shah, Sandeep N, Wickremasinghe, Sanjeewa, Haug, Sara Joy, Adrean, Sean D, Priglinger, Siegfried G, Esposti, Simona Degli, Guest, Stephen, Huddleston, Stephen, Itty, Sujit, Moon, Suk Jin, Bhatia, Sumit P, Gupta, Sunil, Patel, Sunil S, Garg, Sunir J, Joshi, Sunir, Nghiem-Buffet, Sylvia, Johnson, T Mark, Jaouni, Tareq, Ach, Thomas, Williams, Thomas R, Sheidow, Thomas, Cleland, Timothy P, You, Timothy T, Peto, Tunde, Konidaris, Vasileios, Gonzalez, Victor H, Korda, Vladimir, Freeman, William R, Bridges, William Z, Barak, Yoreh, Zagorski, Zbigniew, Yehoshua, Zohar, Dubska, Zora, Rosenfeld, Philip J, Guymer, Robyn H, Boyer, David, Grossi, Federico, Korobelnik, Jean-Francois, Slakter, Jason S, Waheed, Nadia K, Metlapally, Ravi, Steinle, Nathan, Francone, Anibal A, Hu, Allen, Deschatelets, Pascal, Francois, Cedric, Bliss, Caleb, Monés, Jordi, and Ribeiro, Ramiro

Published
2023
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8. A Randomized Controlled Trial of OPT-302, a VEGF-C/D Inhibitor for Neovascular Age-Related Macular Degeneration

Author

Kousal, Bohdan, Studnicka, Jan, Veith, Michal, Creuzot-Garcher, Catherine, De Bats, Flore, Gaucher, David, Mauget-Faysse, Martine, Souied, Eric, Tadayoni, Ramin, Facsko, Andrea, Kerénvi, Agnes, Papp, Andras, Tsorbatzoglou, Alexis, Vogt, Gabor, Barak, Yoreh, Chowers, Itay, Goldstein, Michaella, Hanhart, Joel, Morori-Katz, Haya, Rosenblatt, Irit, Rubowitz, Alexander, Netzer, Oren Tomkins, Bandello, Francesco, Ciardella, Antonio, Ricci, Federico, Staurenghi, Giovanni, Virgili, Gianni, Baumane, Kristine, Laganovska, Guna, Ozolina, Signe, Strautmane, Ilze, Kaluzny, Bartlomiej, Mackiewicz, Jerzy, Misiuk-Hoilo, Marta, Mrukwa-Kominek, Ewa, Oleksy, Piotr, Raczynska, Krystyna, Zarnowski, Tomasz, Adan, Alfredo, Araiz, Javier, Boixadera, Anna, Fernández-Vega, Alvaro, Layana, Alfredo Garcia, Gomez-Ulla, Francisco, Montero, Javier, Ruiz Moreno, Jose Maria, Gilmour, David, Jackson, Timothy, Liyanage, Sidath, Membrey, Luke, Menon, Geeta, Narendran, Niro, Sivaprasad, Sobha, Alfaro, Daniel, Antoszyk, Andrew, Baker, Carl, Batille, Ivan, Berger, Brian, Boyer, David, Bridges, William, Brooks, Harold, Brown, David, Chang, Margaret, Chao, Daniel, Chen, Sanford, Crawford, Courtney, Dugel, Pravin, Eaton, Alexander, Eichenbaum, David, Fein, Jordana, Feiner, Leonard, Flaxel, Christina, Garber, Frank, Gordon, Alan, Gupta, Sunil, Haegedorn, Curtis, Hampton, George, Hanscom, Thomas, Hershberger, Vrinda, Kaiser, Peter, Katz, Randy, Khanani, Arshad, Kruger, Erik, Marcus, Denis, Ohr, Matthew, Patel, Sunil, Pearlman, Joel, Pesavento, Richard, Pieramici, Dante, Pitcher, John, Prensky, Jay, Randolf, John, Regillo, Carl, Rose, Steven, Samuel, Michael, Schneiderman, Todd, Shah, Sumit, Singer, Michael, Steinle, Nathan, Stoller, Glenn, Thach, Alan, Thompson, John, Varenhorst, Michael, Wagner, Alan, Walker, Joseph, Wells, John, Williams, Jonathan, Wong, Robert, Wykoff, Charles, Jackson, Timothy L., Slakter, Jason, Buyse, Marc, Wang, Kun, Dugel, Pravin U., Wykoff, Charles C., Boyer, David S., Gerometta, Michael, Baldwin, Megan E., and Price, Clare F.

Published
2023
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13. TELANGIECTATIC CAPILLARIES CAUSING PERSISTENT DIABETIC MACULAR EDEMA SUCCESSFULLY TREATED BY PHOTODYNAMIC THERAPY.

Author

Schaeffer, Marion, Dormegny, Léa, Speeg-Schatz, Claude, Sauer, Arnaud, Bourcier, Tristan, and Gaucher, David

Abstract

Purpose: To report two cases of persistent macular edema caused by the exudation of diabetic telangiectatic capillaries (TelCaps), which have been successfully treated with photodynamic therapy (PDT). Methods: Review of data from two patients suffering from persistent macular edema caused by parafoveolar TelCaps. In both cases, conventional laser was impossible because TelCaps were to close from foveal center. Results: The use of focal PDT on perifoveolar TelCaps permitted to reduce persistent macular edema and to avoid inefficient intravitreal anti-vascular epithelial growth factor or steroid injections. In both cases, visual acuity was fully restored four to six months after PDT. Central macular thickness was also normalized in the first case and significantly reduced in the second case. In both cases, visual gain was sustained throughout the whole follow-up period (2 and 1 year, respectively). Conclusion: Photodynamic therapy can be helpful to treat diabetic macular edema caused by TelCaps nonresponding to approved intravitreal therapy or for which conventional laser is contraindicated. [ABSTRACT FROM AUTHOR]

Published
2024
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14. No association of endothelial lipase and aldose reductase polymorphisms with proliferative diabetic retinopathy: results of the French prospective multicenter REDIAGEN study

Author

HENRY, Adrien, primary, BOIGELOT, Tiffany, additional, MOURA, Thomas FERREIRA DE, additional, LECLERCQ, Isabelle, additional, BARBE, Coralie, additional, THIERY, Aurore, additional, DJERADA, Zoubir, additional, NAZEYROLLAS, Pierre, additional, CLAVEL, Christine, additional, CORNILLET-LEFEBVRE, Pascale, additional, BERROD, Jean-Paul, additional, CREUZOT-GARCHER, Catherine, additional, MEYER, Laurent, additional, GAUCHER, David, additional, GUERCI, Bruno, additional, LENOBLE, Patrick, additional, MILAZZO, Solange, additional, PERONE, Jean-Marc, additional, ARNDT, Carl, additional, and DURLACHd, Vincent, additional

Published
2024
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17. The Use of Dog Guides for Orientation and Mobility by Individuals With the Argus II Retinal Prosthesis: A Case Series

Author

Flourence, Marine, primary, Merlini, Francesco, additional, Leffel, Ana, additional, Fossati, Marco, additional, Meddouri, Sophia, additional, Carbone, Valentina, additional, Benninghofen, Matthias, additional, Studer, Fouzia, additional, Dollfus, Hélène, additional, Gaucher, David, additional, Kirchhof, Bernd, additional, Mura, Marco, additional, and Fisher, Andy, additional

Published
2023
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21. ADVERSE EVENTS OF THE ARGUS II RETINAL PROSTHESIS: Incidence, Causes, and Best Practices for Managing and Preventing Conjunctival Erosion

Author

Rizzo, Stanislao, Barale, Pierre-Olivier, Ayello-Scheer, Sarah, Devenyi, Robert G., Delyfer, Marie-Noëlle, Korobelnik, Jean-François, Rachitskaya, Aleksandra, Yuan, Alex, Jayasundera, K. Thiran, Zacks, David N., Handa, James T., Montezuma, Sandra R., Koozekanani, Dara, Stanga, Paulo E., da Cruz, Lyndon, Walter, Peter, Augustin, Albert J., Chizzolini, Marzio, Olmos de Koo, Lisa C., Ho, Allen C., Kirchhof, Bernd, Hahn, Paul, Vajzovic, Lejla, Iezzi, Raymond, Jr, Gaucher, David, Arevalo, J. Fernando, Gregori, Ninel Z., Grisanti, Salvatore, Özmert, Emin, Yoon, Young Hee, Kokame, Gregg T., Lim, Jennifer I., Szurman, Peter, de Juan, Eugene, Jr, Rezende, Flavio A., Salzmann, Joël, Richard, Gisbert, Huang, Suber S., Merlini, Francesco, Patel, Uday, Cruz, Cynthia, Greenberg, Robert J., Justus, Sally, Cinelli, Laura, and Humayun, Mark S.

Published
2020
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22. ADVERSE EVENTS OF THE ARGUS II RETINAL PROSTHESIS: Incidence, Causes, and Best Practices for Managing and Preventing Conjunctival Erosion

Author

Rizzo, Stanislao, Barale, Pierre-Olivier, Ayello-Scheer, Sarah, Devenyi, Robert G., Delyfer, Marie-Noëlle, Korobelnik, Jean-François, Rachitskaya, Aleksandra, Yuan, Alex, Jayasundera, K. Thiran, Zacks, David N., Handa, James T., Montezuma, Sandra R., Koozekanani, Dara, Stanga, Paulo E., da Cruz, Lyndon, Walter, Peter, Augustin, Albert J., Chizzolini, Marzio, Olmos de Koo, Lisa C., Ho, Allen C., Kirchhof, Bernd, Hahn, Paul, Vajzovic, Lejla, Iezzi, Raymond, Jr, Gaucher, David, Arevalo, J. Fernando, Gregori, Ninel Z., Grisanti, Salvatore, Özmert, Emin, Yoon, Young Hee, Kokame, Gregg T., Lim, Jennifer I., Szurman, Peter, de Juan, Eugene, Jr, Rezende, Flavio A., Salzmann, Joël, Richard, Gisbert, Huang, Suber S., Merlini, Francesco, Patel, Uday, Cruz, Cynthia, Greenberg, Robert J., Justus, Sally, Cinelli, Laura, and Humayun, Mark S.

Published
2018
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24. Single-masked Randomized Phase II Study Assessing Two Forms of Hypofractionated Proton Therapy in Patients with Large Choroidal Melanomas

Author

THARIAT, Juliette, primary, MATHIS, Thibaud, additional, PACE-LOSCOS, Tanguy, additional, PEYRICHON, Marie Laure, additional, MASCHI, Celia, additional, ROSIER, Laurence, additional, NGUYEN, Minh, additional, BONNIN, Nicolas, additional, ALOI, Deborah, additional, GASTAUD, Lauris, additional, GAUCHER, David, additional, CAUJOLLE, Jean-Pierre, additional, CHÂTEAU, Yann, additional, and HERAULT, Joel, additional

Published
2023
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26. Endophthalmitis After Intravitreal Injections: Incidence, Presentation, Management, and Visual Outcome

Author

Berthon, Laurent, Maftouhi, Quaranta-El, Bakhti, Amina, Conrath, John, Le Mer, Yannick, Ramahefasolo, Christiane Besse, Coscas, Florence, Français, Catherine, Grenet, Typhaine, Cohen, Salomon Yves, Uzzan, Joël, Razavi, Sam, Saleh, Maher, Delbosc, Bernard, Chaine, Gilles, Fajnkuchen, Franck, Giocanti, Audrey, Delyfer, Marie-Noëlle, Korobelnik, Jean-François, Querques, Giuseppe, Chevreaud, Olivier, Souied, Eric, Musson, Cécile, Chiquet, Christophe, Fortoul, Vincent, Kodjikian, Laurent, Straub, Morgane, Burillon, Carole, Berrod, Jean-Paul, Baillif, Stéphanie, Girmens, Jean-François, Pérol, Julien, Leveziel, Nicolas, Boissonnot, Michèle, Muraine, Marc, Gaucher, David, Le Lez, Marie-Laure, Pisella, Pierre-Jean, Dossarps, Denis, Bron, Alain M., Koehrer, Philippe, Aho-Glélé, Ludwig S., and Creuzot-Garcher, Catherine

Published
2015
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36. Management of postoperative inflammation after cataract and complex ocular surgeries: a systematic review and Delphi survey

Author

Aptel, Florent, Colin, Cyrille, Kaderli, Sema, Deloche, Catherine, Bron, Alain M, Stewart, Michael W, Chiquet, Christophe, Baillif, Stephanie, Berrocal, Mariah, Berrod, Jean-paul, Bron, Alain M, Chiquet, Christophe, Devin, François, Delyfer, Marie-noelle, Denis, Philippe, De smet, Marc D, Fogagnolo, Paolo, Gaucher, David, Germain, Philippe, Bernard, Agnès Glacet, Kodjikian, Laurent, Labbè, Antoine, Labetoulle, Marc, Mansouri, Kaweh, Meyer, Carsten H, Murray, Timothy G, Myers, Jonathan S, Pournaras, Constantin J, Rouberol, Frédéric, Saleh, Maher, Singer, Michael A, Stewart, Michael W, Tatham, Andrew J, and Wolfensberger, Thomas

Published
2017
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38. Efficacy and Safety of 0.1% Cyclosporine versus 2% Cyclosporine in the Treatment of Severe Vernal Keratoconjunctivitis in Children

Author

Bourcier,Tristan, Dory,Anne, Dormegny,Lea, Alcazar,Joffrey, Gaucher,David, Sauer,Arnaud, Bourcier,Tristan, Dory,Anne, Dormegny,Lea, Alcazar,Joffrey, Gaucher,David, and Sauer,Arnaud

Abstract

Tristan Bourcier,1 Anne Dory,2 Lea Dormegny,1 Joffrey Alcazar,1 David Gaucher,1 Arnaud Sauer1 1Department of Ophthalmology, Strasbourg University Hospital, University of Strasbourg, Strasbourg, France; 2Pharmacy, Strasbourg University Hospital, University of Strasbourg, Strasbourg, FranceCorrespondence: Arnaud Sauer, Department of Ophthalmology, Nouvel Hôpital Civil, Strasbourg University Hospital, BP426, Strasbourg, 67091, France, Email arnaud.sauer@chru-strasbourg.frIntroduction: Vernal keratoconjunctivitis (VKC) is an inflammatory condition in children that can cause severe eye complications. Treatment is based on corticosteroid therapy during flare-ups, then antihistamines and cyclosporine in calmer periods. The dosage and posology of cyclosporine are subject to debate.Methods: The aim of the study is to compare the evolution in symptomatic and clinical scores, and need for topical corticosteroid treatment in a population of children with severe VKC treated with two dosages of cyclosporine treatment (0.1% and 2%). Data were compiled on inclusion then every three months from March, with a total follow-up duration of 12 months. Data concerning patient evolutions and complications were collected for the two treatment groups.Results: The mean age of the 46 children was 8.8 ± 2.4 years with age at onset of symptoms of 5.1 ± 0.9 years. The cohort was predominantly (65%) male. Corticosteroid dependence on inclusion was present in 52% of the children included. A significant improvement in the various symptomatic and clinical scores was observed following treatment with cyclosporine (0.1% and 2%). Use of topical corticosteroid treatment reduced from 19 drops per month on inclusion to 4 drops per month at 12 months. Safety was comparable for the two groups.Conclusion: Treatments with cyclosporine 0.1% and 2% lead to a favourable evolution in clinical and symptomatic scores and reduced corticosteroid use. Cyclosporine 0.1% is an interesting alternative to the 2% dosage

Published
2022

39. Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials

Author

Heier, Jeffrey S, Lad, Eleonora M, Holz, Frank G, Rosenfeld, Philip J, Guymer, Robyn H, Boyer, David, Grossi, Federico, Baumal, Caroline R, Korobelnik, Jean-Francois, Slakter, Jason S, Waheed, Nadia K, Metlapally, Ravi, Pearce, Ian, Steinle, Nathan, Francone, Anibal A, Hu, Allen, Lally, David R, Deschatelets, Pascal, Francois, Cedric, Bliss, Caleb, Staurenghi, Giovanni, Monés, Jordi, Singh, Rishi P, Ribeiro, Ramiro, Wykoff, Charles C, Cole, Abosede O, Gerstenblith, Adam T, Kotagiri, Ajay, Edwards, Albert O, Zambrano, Alberto D, Eaton, Alexander M, Rubowitz, Alexander, Lyon, Alice T, Chiang, Allen, Ho, Allen, Hu, Allen Y, Guerami, Amir H, Dessouki, Amr L, de Carvalho, André Corrêa Maia, Emanuelli, Andrés, Chang, Andrew A, Antoszyk, Andrew N, Francone, Anibal Andrés, Prasad, Anita, Wolf, Armin, Khanani, Arshad M, Abbey, Ashkan Michael, Moulana, Asma, Wihelm, Barbara, Sikorski, Bartosz L, Kuppermann, Baruch D, Wolff, Benjamin, Jewart, Brian H, Do, Brian K, Chan-Kai, Brian T, Mein, Calvin, Hoyng, Carel B, Awh, Carl C, Regillio, Carl, Zeolite, Carlos, Baumal, Caroline R, Creuzot-Garcher, Catherine, Maury, Catherine Français, Wykoff, Charles C, Newell, Charles K, Jhaveri, Chirag, Lohmann, Chris P, Dinah, Christiana B, Ma, Colin, Crawford, Courtney, Parke, D Wilkin, Lavinsky, Daniel, Roth, Daniel, Pieramici, Dante J, Moshfeghi, Darius M, Levin, Darrin, Saperstein, David A, Brown, David, Gaucher, David, Lally, David R, Liao, David S, Brown, David Warren, Goldstein, Debra, Marcus, Dennis, Chan, Derek G, Dhoot, Dilsher, Tacite, Domingo, Zalewski, Dominik, Espana, Edgar M, Lad, Eleonora M, Souied, Eric H, Suan, Eric P, Eting, Eva, Sola, Federico Furno, de Bats, Flore, Bandello, Francesco, Gómez-Ulla, Francisco, Devin, François, Holz, Frank G, Chen, Fred K, Makkouk, Fuad, Dyer, Gawain, Spital, George, Staurenghi, Giovanni, Stoller, Glenn, Cousins, Gwen, Salehi-Had, Hani, Agostini, Hansjürgen, Eleftheriadis, Haralabos, Weiss, Harold, Sultan, Harris C, Massé, Hélène, Pearce, Ian, Dias, Indra, Barbazetto, Irene, Rosenblatt, Irit, Suñer, Ivan J, Kovach, Jaclyn L, Kaluzny, Jakub, Borthwick, James, Howard, James G, Wong, James, Ernest, Jan, Němčanský, Jan, Ysasaga, Jason Edward, Handza, Jason M, Moreno, Javier Antonio Montero, Korobelnik, Jean-François, Heier, Jeffrey S, Arnold, Jennifer J, Brown, Jeremiah, Bafalluy, Joaquin, Pearlman, Joel, Pitcher, John D, Kitchens, John, Carlson, John P, Gilhotra, Jolly, Fein, Jordana, Monés, Jordi M, Luna, José Domingo, Moreno, José María Ruiz, Coney, Joseph M, Sallum, Juliana Maria Ferraz, Olsen, Karl R, Blobner, Katharina, Macoul, Katherine A, Oh, Kean T, Malik, Khurram Javed, Hattenbach, Lars-Olof, Kodjikian, Laurent, Neto, Laurentino Biccas, Singerman, Lawrence J, Altay, Lebriz, Sheck, Leo-H, Feiner, Leonard, Harris, Lindsey D, Chishold, Lionel D, Rao, Llewelyn J, Nehemy, Márcio Bittar, Elizalde, Maria Jose Capella, Gamulescu, Maria-Andreea, Saravia, Mario J, Johnson, Mark W, McKibbin, Martin, Maccumber, Mathew, Vidosevich, Matko, Ohr, Matthew P, Samuel, Michael A, Singer, Michael A, Cassell, Michael, Dollin, Michael, Elman, Michael J, Ip, Michael S, Goldstein, Michaella, Busquets, Miguel, Mititelu, Mihai, Shah, Milan, Veith, Miroslav, Fineman, Mitchell, Varano, Monica, Christmas, Nancy, Steinle, Nathan C, Chaudhry, Nauman, Chinskey, Nicholas D, Eter, Nicole, London, Nikolas J S, Mathalone, Nurit, Schlottmann, Patricio G, Coady, Patrick, Higgins, Patrick M, Raskauskas, Paul A, Yates, Paul A, Bernstein, Paul, Mitchell, Paul, Monsour, Paul, Raphaelian, Paul V, Stanga, Paulo E, Stodulka, Pavel, Issa, Peter Charbel, Pavan, Peter, Ferrone, Phil J, Oleksy, Piotr, Abraham, Prema, Mruthyunjaya, Prithvi, Nguyen, Quan Dong, Reddy, Rahul K, Khurana, Rahul N, Tuli, Raman, Tadayoni, Ramin, Katz, Randy Steven, Arora, Rashi, Schlingemann, Reinier O, Rosen, Richard B, Gale, Richard, Scartozzi, Richard, Isernharge, Ricky, Singh, Rishi P, Stoltz, Robert A, Avery, Robert L, Wirthlin, Robert S, Guymer, Robyn, Goldberg, Roger A, Frenkel, Ronald, Belfort, Rubens Jr, Mohand-Said, Saddek, Grisanti, Salvatore, Razavi, Sam, Fraser-Bell, Samantha, Shah, Sandeep N, Wickremasinghe, Sanjeewa, Haug, Sara Joy, Adrean, Sean D, Priglinger, Siegfried G, Esposti, Simona Degli, Guest, Stephen, Huddleston, Stephen, Itty, Sujit, Moon, Suk Jin, Bhatia, Sumit P, Gupta, Sunil, Patel, Sunil S, Garg, Sunir J, Joshi, Sunir, Nghiem-Buffet, Sylvia, Johnson, T Mark, Jaouni, Tareq, Ach, Thomas, Williams, Thomas R, Sheidow, Thomas, Cleland, Timothy P, You, Timothy T, Peto, Tunde, Konidaris, Vasileios, Gonzalez, Victor H, Korda, Vladimir, Freeman, William R, Bridges, William Z, Barak, Yoreh, Zagorski, Zbigniew, Yehoshua, Zohar, and Dubska, Zora

Abstract

Geographic atrophy is a leading cause of progressive, irreversible vision loss. The objectives of OAKS and DERBY were to assess the efficacy and safety of pegcetacoplan compared with sham treatment in patients with geographic atrophy.

Published
2023
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43. Choroidal thickness and vessel pattern in myopic eyes with dome-shaped macula.

Author

Negrier, Pierre, Couturier, Aude, Gaucher, David, Touhami, Sara, Guern, Guillaume Le, Tadayoni, Ramin, Gaudric, Alain, and Philippakis, Elise

Abstract

Aim To analyse the choroidal thickness (CT) and vessel pattern of myopic patients with dome-shaped macula (DSM) and their association with the DSM axis and serous retinal detachment (SRD). Methods Retrospective study. The CT and vessel pattern were assessed on optical coherence tomography (OCT), OCT-angiography and ultra-wide-field photography. Results 27 eyes of 18 subjects (mean age: 65 years) were included. Compared with the 11 eyes (41%) with horizontal DSM, the 16 eyes (59%) with vertical DSM had a shorter axial length (25.8±2 mm vs 28.3±2.5 mm; p=0.01), a higher mean macular bulge height (624.4±207 µm vs 255.4±160.3 µm; p=0.0001) and a thicker CT (183.1±91.1 µm vs 72±38.3 µm; p<0.001). Large choroidal vessels crossed the macular area in 75% of eyes with vertical DSM vs 27% of eyes with horizontal DSM (p=0.02), whereas a watershed zone framing the macula was more often seen in horizontal DSM (72% vs 25%, p=0.02). Thirteen eyes (48%) had an SRD that was not associated with the DSM axis, the mean bulge height, the CT or the vessel pattern. Conclusion The presence of an SRD did not correlate with the DSM axis, the CT or the vessel pattern. However, the rate of large choroidal vessels crossing the macula was higher in vertical DSM than in horizontal DSM. [ABSTRACT FROM AUTHOR]

Published
2022
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45. State of the Art in Robot-Assisted Eye Surgery

Author

Bourcier, Tristan, additional, Dormegny, Léa, additional, Sauer, Arnaud, additional, Nardin, Mathieu, additional, Becmeur, Pierre-Henri, additional, Chammas, Jimmy, additional, Gaucher, David, additional, Ballonzoli, Laurent, additional, Speeg, Claude, additional, Liverneaux, Philippe, additional, Vix, Michel, additional, Marescaux, Jacques, additional, and Mutter, Didier, additional

Published
2021
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