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216 results on '"Gauci, Charles G."'

3. Understanding temporal and spatial distribution of intestinal nematodes of horses using faecal egg counts and DNA metabarcoding

Author

Abbas, Ghazanfar, Ghafar, Abdul, Beasley, Anne, Stevenson, Mark A., Bauquier, Jenni, Koehler, Anson V., Wilkes, Edwina J.A., McConnell, Emma, El-Hage, Charles, Carrigan, Peter, Cudmore, Lucy, Hurley, John, Gauci, Charles G., Beveridge, Ian, Jacobson, Caroline, Nielsen, Martin K., Hughes, Kristopher J., and Jabbar, Abdul

Published
2024
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4. Prevalence and diversity of ascarid and strongylid nematodes in Australian Thoroughbred horses using next-generation sequencing and bioinformatic tools

Author

Abbas, Ghazanfar, Ghafar, Abdul, Bauquier, Jenni, Beasley, Anne, Ling, Elysia, Gauci, Charles G., El-Hage, Charles, Wilkes, Edwina J.A., McConnell, Emma, Carrigan, Peter, Cudmore, Lucy, Hurley, John, Beveridge, Ian, Nielsen, Martin K., Stevenson, Mark A., Jacobson, Caroline, Hughes, Kristopher J., and Jabbar, Abdul

Published
2023
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7. Global prevalence of Eimeria species in goats: a systematic review and meta-analysis.

Author

Ali, Endris A., Ghafar, Abdul, Angeles-Hernandez, Juan C., Yaseen, Muhammad, Gauci, Charles G., Beveridge, Ian, Baxendell, Sandra, and Jabbar, Abdul

Subjects
PROTOZOAN diseases, EIMERIA, FACTOR analysis, GOATS, COCCIDIOSIS, CONFIDENCE intervals
Abstract

Background: Coccidiosis is a protozoal disease caused by Eimeria species, the main symptom of which is diarrhea. Eimeria spp. infection can cause weight loss and ill-thrift in goats, and in severe cases, it can lead to mortality in kids, resulting in economic losses for the goat industry. This study aimed to determine the global prevalence of Eimeria spp. in goats and to identify the possible predictors of heterogeneity among selected studies. Methods: Data were retrieved from five databases of major global importance (PubMed, Web of Science, CAB Direct, Scopus, and Google Scholar), with 255 studies published between 1963 and 2022 being included. A random-effects model was used to calculate pooled prevalence estimates with 95% confidence intervals (CI), followed by subgroup meta-analysis and meta-regression analysis to identify factors contributing to high prevalence and explore sources of heterogeneity among studies. Results: The estimated global prevalence of Eimeria spp. in goats was 62.9% (95% CI: 58.6–67.2). Our results indicated high inter-study variability (inconsistency index (I2) = 99.7%, p < 0.01). Among the variables analyzed, regions and quality of studies were the most significant predictors of heterogeneity. According to the region-based subgroup meta-analysis, North America had the highest estimated prevalence of Eimeria spp. (92.2, 95% CI: 82.7–98.2), followed by Europe (86.6, 95% CI: 79.8–92.3), while Asia had the lowest prevalence (52.0, 95% CI: 45.9–58.1). Most countries (n = 42/56) had an estimated prevalence above the overall pooled estimate (>62.9%). The subgroup of studies conducted in 2000 or later presented a lower prevalence of 59.6% (95% CI: 54.7–64.3). Studies with a score of 5–7 had a significantly higher prevalence (72.4, 95% CI: 66.2–78.2) than studies with low or medium scores (p < 0.01). The prevalence of Eimeria spp. in goats detected with conventional and molecular methods was 67.3% (95% CI: 47.0–84.7). Only 47% (119/255) of the studies provided details on identifying Eimeria at the species level. Overall, more than 26 Eimeria spp. have been identified in goats globally. Among these, the most frequently reported and pathogenic species were E. arloingi (115/119), E. ninakohlyakimovae (108/119), E. christenseni (94/119), and E. caprina (71/119). Other valid species that were reported less frequently include E. alijevi , E. hirci , E. caprovina , E. aspheronica and E. jolchijevi. Conclusion: These findings suggest that the pathogenic Eimeria spp. are widespread in goats globally. Given the high prevalence and the extensive distribution of pathogenic Eimeria spp. in goats, it is recommended that integrated parasite management approaches be implemented for the effective control of coccidiosis in goats. [ABSTRACT FROM AUTHOR]

Published
2025
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14. Pilot field trial of the EG95 vaccine against ovine cystic echinococcosis in Rio Negro, Argentina: 8 years of work

Author

Larrieu, Edmundo, Mujica, Guillermo, Araya, Daniel, Labanchi, Jose Luis, Arezo, Marcos, Herrero, Eduardo, Santillán, Graciela, Vizcaychipi, Katherina, Uchiumi, Leonardo, Salvitti, Juan Carlos, Grizmado, Claudia, Calabro, Arnoldo, Talmon, Gabriel, Sepulveda, Luis, Galvan, Jose Maria, Cabrera, Marta, Seleiman, Marcos, Crowley, Pablo, Cespedes, Graciela, García Cachau, Mariela, Gino, Lilia, Molina, Leonardo, Daffner, Jose, Gauci, Charles G., Donadeu, Meritxell, and Lightowlers, Marshall W.

Published
2019
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16. A national survey of anthelmintic resistance in ascarid and strongylid nematodes in Australian thoroughbred horses

Author

Abbas, Ghazanfar, primary, Ghafar, Abdul, additional, McConnell, Emma, additional, Beasley, Anne, additional, Bauquier, Jenni, additional, Wilkes, Edwina J.A., additional, El-Hage, Charles, additional, Carrigan, Peter, additional, Cudmore, Lucy, additional, Hurley, John, additional, Gauci, Charles G., additional, Beveridge, Ian, additional, Ling, Elysia, additional, Jacobson, Caroline, additional, Stevenson, Mark A., additional, Nielsen, Martin K., additional, Hughes, Kristopher J., additional, and Jabbar, Abdul, additional

Published
2023
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18. Comparison of Kato–Katz, PCR and coproantigen for the diagnosis of Taenia solium taeniasis

Author

Lightowlers, Marshall W., primary, Mananjara, Diana Edithe Andria, additional, Rakotoarinoro, Mihajamanana, additional, Rakotoarison, Valisoa C., additional, Raliniaina, Modestine, additional, Rasamoelina-Andriamanivo, Harentsoaniaina, additional, Gauci, Charles G., additional, Jabbar, Abdul, additional, Mwape, Kabemba E., additional, Donadeu, Meritxell, additional, Ramiandrasoa, Noromanana Sylvia, additional, and Nely, Jose Alphonse, additional

Published
2023
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21. Unravelling the Diversity of Microorganisms in Ticks from Australian Wildlife

Author

Ghafar, Abdul, primary, Davies, Nick, additional, Tadepalli, Mythili, additional, Breidahl, Amanda, additional, Death, Clare, additional, Haros, Philip, additional, Li, Yuting, additional, Dann, Peter, additional, Cabezas-Cruz, Alejandro, additional, Moutailler, Sara, additional, Foucault-Simonin, Angélique, additional, Gauci, Charles G., additional, Stenos, John, additional, Hufschmid, Jasmin, additional, and Jabbar, Abdul, additional

Published
2023
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23. Pilot field trial of the EG95 vaccine against ovine cystic echinococcosis in Rio Negro, Argentina: Early impact and preliminary data

Author

Larrieu, Edmundo, Herrero, Eduardo, Mujica, Guillermo, Labanchi, Jose Luis, Araya, Daniel, Grizmado, Claudia, Calabro, Arnoldo, Talmon, Gabriel, Ruesta, Guillermo, Perez, Alicia, Gatti, Antonio, Santillán, Graciela, Cabrera, Marta, Arezzo, Marcos, Seleiman, Marcos, Cavagión, Laura, Cachau, Mariela García, Alvarez Rojas, Cristian A., Gino, Lilia, Gauci, Charles G., Heath, David D., Lamberti, Roberto, and Lightowlers, Marshall W.

Published
2013
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32. Additional file 1 of Molecular detection of Strongyloides sp. in Australian Thoroughbred foals

Author

Abbas, Ghazanfar, Ghafar, Abdul, Koehler, Anson V., Bauquier, Jenni, Wilkes, Edwina J. A., Jacobson, Caroline, Beasley, Anne, Hurley, John, Cudmore, Lucy, Carrigan, Peter, Tennent-Brown, Brett, El-Hage, Charles, Nielsen, Martin K., Gauci, Charles G., Hughes, Kristopher J., Beveridge, Ian, and Jabbar, Abdul

Abstract

Additional file 1: Figure S1. Alignment of the small subunit nuclear ribosomal DNA (18S) sequence of Strongyloides sp. determined herein (bold) and the selected reference sequences. A dot indicates an identical nucleotide with respect to the sequence of Strongyloides sp.; a dash indicates an insertion/deletion (indel) event.

Published
2021
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37. Control of cystic echinococcosis in the Middle Atlas, Morocco: Field evaluation of the EG95 vaccine in sheep and cesticide treatment in dogs

Author

Amarir, Fatimaezzahra, primary, Rhalem, Abdelkbir, additional, Sadak, Abderrahim, additional, Raes, Marianne, additional, Oukessou, Mohamed, additional, Saadi, Aouatif, additional, Bouslikhane, Mohammed, additional, Gauci, Charles G., additional, Lightowlers, Marshall W., additional, Kirschvink, Nathalie, additional, and Marcotty, Tanguy, additional

Published
2021
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41. An Assessment of the Molecular Diversity of Ticks and Tick-Borne Microorganisms of Small Ruminants in Pakistan

Author

Ghafar, Abdul, primary, Khan, Adil, additional, Cabezas-Cruz, Alejandro, additional, Gauci, Charles G., additional, Niaz, Sadaf, additional, Ayaz, Sultan, additional, Mateos-Hernández, Lourdes, additional, Galon, Clemence, additional, Nasreen, Nasreen, additional, Moutailler, Sara, additional, Gasser, Robin B., additional, and Jabbar, Abdul, additional

Published
2020
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42. Protection against cystic echinococcosis in sheep using an Escherichia coli -expressed recombinant antigen (EG95) as a bacterin.

Author

Gauci, Charles G., Jenkins, David J., and Lightowlers, Marshall W.

Subjects
*ECHINOCOCCUS granulosus, *BACTERIAL vaccines, *ESCHERICHIA coli, *ECHINOCOCCOSIS, *RECOMBINANT proteins, *VACCINE trials, *WOOL
Abstract

The EG95 recombinant vaccine is protective against cystic echinococcus in animal intermediate hosts. Preparation of the existing, registered EG95 vaccines involves semi-purification of the vaccine protein, adding to the cost of production. Truncation of the EG95 cDNA, shortening both the amino and carboxy-termini of the protein, leads to high levels of recombinant protein expression. The recombinant EG95 protein was prepared as a bacterin from clarified, whole bacterial lysate, and used in a vaccine trial in sheep against an experimental challenge infection with Echinococcus granulosus eggs. The EG95 bacterin was found to induce 98% protection. Use of this in a new generation EG95 vaccine would simplify production, facilitate new sources of the vaccine and potentially enhance uptake of vaccination in control of E. granulosus transmission. [ABSTRACT FROM AUTHOR]

Published
2023
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43. Implementation of a practical and effective pilot intervention against transmission of Taenia solium by pigs in the Banke district of Nepal

Author

Poudel, Ishab, Sah, Keshav, Subedi, Suyog, Kumar Singh, Dinesh, Kushwaha, Peetambar, Colston, Angela, Gauci, Charles G., Donadeu, Meritxell, and Lightowlers, Marshall W.

Subjects
lcsh:Arctic medicine. Tropical medicine, Asia, lcsh:RC955-962, Swine, Immunology, Animal Slaughter, Hands, Pilot Projects, Neurocysticercosis, Geographical Locations, Drug Therapy, Nepal, parasitic diseases, Taenia solium, Medicine and Health Sciences, Parasitic Diseases, Prevalence, Animals, Humans, Public and Occupational Health, Musculoskeletal System, Animal Management, Mammals, Swine Diseases, Vaccines, Synthetic, Cysticercosis, Pharmaceutics, lcsh:Public aspects of medicine, Incidence, Vaccination, Organisms, Biology and Life Sciences, Eukaryota, lcsh:RA1-1270, Agriculture, Tropical Diseases, Vaccination and Immunization, Arms, Helminth Infections, Body Limbs, Antigens, Helminth, Vertebrates, Amniotes, People and Places, Benzimidazoles, Preventive Medicine, Anatomy, Research Article, Neglected Tropical Diseases
Abstract

Taenia solium is a zoonotic cestode parasite which causes human neurocysticercosis. Pigs transmit the parasite by acting as the intermediate host. An intervention was implemented to control transmission of T. solium by pigs in Dalit communities of Banke District, Nepal. Every 3 months, pigs were vaccinated with the TSOL18 recombinant vaccine (Cysvax, IIL, India)) and, at the same time, given an oral treatment with 30mg/kg oxfendazole (Paranthic 10% MCI, Morocco). The prevalence of porcine cysticercosis was determined in both an intervention area as well as a similar no intervention control area, among randomly selected, slaughter-age pigs. Post mortem assessments were undertaken both at the start and at the end of the intervention. Participants conducting the post mortem assessments were blinded as to the source of the animals being assessed. At the start of the intervention the prevalence of porcine cysticercosis was 23.6% and 34.5% in the control and intervention areas, respectively. Following the intervention, the prevalence of cysticercosis in pigs from the control area was 16.7% (no significant change), whereas no infection was detected after complete slicing of all muscle tissue and brain in animals from the intervention area (P = 0.004). These findings are discussed in relation to the feasibility and sustainability of T. solium control. The 3-monthly vaccination and drug treatment intervention in pigs used here is suggested as an effective and practical method for reducing T. solium transmission by pigs. The results suggest that applying the intervention over a period of years may ultimately reduce the number of tapeworm carriers and thereby the incidence of NCC., Author summary Neurocysticercosis is a disease caused by a parasitic infection of the brain. The parasite responsible, Taenia solium, is transmitted by pigs where human sanitation is poor and pigs roam freely. Neurocysticercosis is responsible for many cases of epilepsy in people living in poor, developing countries. The feasibility and sustainability of implementing control measures have been major impediments to reducing the incidence of neurocysticercosis. Recently, two new commercial products have become available which together offer the possibility of interrupting the parasite’s transmission by pigs–the TSOL18 vaccine (Cysvax, IIL, India) and an oxfendazole formulation (Paranthic 10%, MCI, Morocco) licensed for use in pigs for the treatment of cysticercosis. Here we describe the impact of implementing vaccination plus drug treatment of pigs in the Banke district of Nepal. The intervention eliminated the risk of transmission of T. solium by the animals vaccinated and treated during the trial. Application of the vaccination and drug treatment program used here, possibly with strategic use of anthelmintics also in the human population, is an effective option for reducing the incidence of neurocysticercosis in Nepal and elsewhere.

Published
2019

44. Accurate diagnosis of lesions suspected of being caused by Taenia solium in body organs of pigs with naturally acquired porcine cysticercosis

Author

Gauci, Charles G., primary, Ayebazibwe, Chrisostom, additional, Nsadha, Zachary, additional, Rutebarika, Chris, additional, Poudel, Ishab, additional, Sah, Keshav, additional, Singh, Dinesh Kumar, additional, Stent, Andrew, additional, Colston, Angela, additional, Donadeu, Meritxell, additional, and Lightowlers, Marshall W., additional

Published
2019
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