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Changeri ghrita is a medicated ghee formulation, mentioned in Grahani rog chikitsa. Sneha murchana is a procedure prior to Snehapaka. Snehapaka and Murchana bring changes in Sneha. Materials and Methods: Two batches of Changeri ghrita prepared using Murchita and Amurchit ghrita. Prepared Ghrita subjected to physico-chemical analysis. Result and Discussion: Specific gravity increased in Murchita ghrita. Refractive index, viscosity, saponification value, iodine values were increased. While acid value is decreased. Peroxide value is slightly increased. Unsaponifiable matter remains unchanged. There was change in organoleptic properties after Murchana. Physico-chemical changes have been occurring except in unsaponifiable matter and congealing point. Peroxide was present in both samples of Amurchit and Murchit Changeri ghrita. Saponification value was increased in Murchit Changeri Ghrita Conclusion: It can be concluded that antioxidants were added during Murchana. Murchana maintains stability of lipid preparation and offer good health impact, increases palatability.

Kshar kalpana is one of important dosage form developed as sub type of panchavidh kashayKalpana.Kshara is alkaline in nature.It is based on the principle that alkaline substances get dissolved in water and can be obtained by evapourating water content.It is derived from certain plants as well as minerals and animal products which contains more alkaline substances.It is first described in Sushrut samhita.There are various methods described in ayurvedic texts to prepare kshara.It has been proved to be effective medicine internally as well as externally.Ksharasutra described by Chakradatta is being used widely by surgeons and appreciated its effectiveness.Kshara also have pharmaceutical application like shodhan,satvaptana of shilajatu,kankshi,parada etc.There is wide range of description available about kshara in ayurvedic texts.Based on plant/mineral or animal product and mode of use,it has various types like pratisaraniya,paniya kshara,Yavakshara,tankan kshara,Apamarga Kshara etc.