1. The validity of the DSM-IV diagnostic classification system of non-affective psychoses
- Author
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Korver-Nieberg, Nikie, Quee, Piotr J., Boos, Heleen B. M., Simons, C., Kahn, Rene S., Cahn, Wiepke, Linszen, Don H., de Haan, Lieuwe, van Os, Jim, Krabbendam, Lydia, Myin-Germeys, Inez, Wiersma, Durk, Bruggemen, Richard, van den Berg, S. E., Schroeder, C. L. A., van der Valk, R., Dekker, N., Meijer, Carin J., Boyette, L. N., Meijer, J., van Dam, D., de Rijke, I., Huinink, S., de Vries, Sanne I., Jansen, M., Bos, D., Hoen, W. P., te West, E. M., Groeneveld, S. H. J., Vergunst, E. M., Swets, Marije, Vothknecht, S., Poleacov, I., van Dijk, D., Spruijt-Metz, D., Hasty, M. T., Geertsa, G., de Baaij, P. M., Metzger, A., van Beveren, Nico J. M., Baldini, M., Grimbergen, F. D., Boerma, M. A. M., Agsteribbe, C., Wisman, H. P., Monden, M. A. H., Bosman, M., van Dijk, M., Klaassen, Rianne M. C., Tang, M. T. C., Luteijn, L. B., Winkel, H., Weisz, H., Strater, A. C. P., Landman, A., Vorstenbosch, Marc A. T. M., Op 't Eijnde, D., Lenders, K., Loyen, S., Roberts, R., Sweers, Kim, Gielen, H., Soons, N., Hintzen, A., Habets van der Poel, C.D., Riske, I., Vossen, C., Martens, E., Apers, S., Wijnhoven, L., Konings, E., Lataster, T., Lardinois, M., Versmissen, D., van der Werf, M., Habets, P., Pfeifer, S., de Loore, E., Heins, M., Oorschot, M., Meys, M., Dietvorst, M., van Zelst, C., Crolla, I., Mengelers, Ron, van Goethem, F., Beuken, W., Byniam, D., Driesen, T., Marcelis, M., Driessen, G., Shazad, A., van Winkel, R., Henquet, C., Kenis, G., Delespaul, P., Anema, P., van Baaren, E. M. J., Bakker, S. C., Caspers, E., Derks, Eske M., van Hemert, S., Hemkes, A., Hijman, Ron, van Leeuwen, M., Machielsen, J. E. H., Ophoff, Roel A., Rais, M., Salden, M., van Someren, H., Strengman, E., Vleesschouwer, M., van Beek, M., van Harten, P. N., Koning, Jeroen P. F., Schep, W., Vollema, M. G., Prins, Bram P, Viester, T., Akdeniz, A., Verweij, K., Kaymaz, K., Van den Heuvel, Frank, Van der Goot, B., Hovens, J.E., Loonen, A. J. M., Bous, J., Veenstra, M., van 't Hag, E., Nienhuis, F. J., Smid, H. G. O. M., Veermans, E., Bartels-Velthuis, Agna A., Duijndam, F., Lugtenberg, T., Knegtering, Henderikus, Blaauw, W., Wunderink, A., Touw, K. P., Arends, J., Slooff, Cees J., Brilman, J., Schomaker, M., van Wijk, Michiel, Wessels, A., Vroom, E., Meijerink, K., Bogert, I., Janssen, W., van den Berk, Inge A. H., Noorthoorn van der Kruijff, E.O., Ising, Helga K., Blom, Jan Dirk, van der Gaag, Mark, Mensen, G., van der Snoek, R., Smit, R., Faber, G., Other departments, ANS - Amsterdam Neuroscience, Adult Psychiatry, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, CCA -Cancer Center Amsterdam, Laboratory Genetic Metabolic Diseases, Graduate School, APH - Amsterdam Public Health, Epidemiology and Data Science, Medical Biology, Obstetrics and Gynaecology, Paediatric Gastroenterology, and Psychiatrie & Neuropsychologie
- Subjects
Adult ,Male ,Psychosis ,Paranoid schizophrenia ,medicine.medical_specialty ,validity ,Adolescent ,Schizoaffective disorder ,behavioral disciplines and activities ,ICD-11 ,5-FACTOR MODEL ,mental disorders ,medicine ,Humans ,Bipolar disorder ,Psychiatry ,SCHEDULE ,Psychiatric Status Rating Scales ,subtypes ,Not Otherwise Specified ,Brief psychotic disorder ,BIPOLAR DISORDER ,Catatonia ,General Medicine ,Middle Aged ,medicine.disease ,PREMORBID ADJUSTMENT ,categorization ,DSM-V ,Diagnostic and Statistical Manual of Mental Disorders ,schizophrenia ,Psychiatry and Mental health ,Psychotic Disorders ,Schizophrenia ,RELIABILITY ,Quality of Life ,Female ,Psychology ,SCHIZOAFFECTIVE DISORDER ,NEGATIVE-SYNDROME-SCALE ,Clinical psychology ,Psychopathology - Abstract
Objective: The schizophrenia and other non-affective disorders categories listed in the DSM-IV, are currently under revision for the development of the fifth edition. The aim of the present study is to demonstrate the validity of these categories by investigating possible differences between diagnostic patient subgroups on various measures. Methods: 1064 patients with a diagnosis of non-affective psychosis (schizophrenia N = 731 (paranoid type 82%), schizoaffective N = 63, schizophreniform N = 120, psychosis not otherwise specified/brief psychotic disorder N = 150) participated in this study. Dependent variables were demographic and clinical characteristics, severity of psychopathology, premorbid and current functioning, and indicators of quality of life. Results: Within the diagnostic group of schizophrenia, no significant differences were observed between paranoid schizophrenia, disorganized, and undifferentiated schizophrenia. Patients with schizophrenia experienced more severe psychopathology and had poorer levels of current functioning compared to patients with psychosis not otherwise specified or brief psychotic disorder. Differences between schizophrenia and schizoaffective disorder were less clear. Conclusion: Our results do not support the validity of schizophrenia subtypes. Schizophrenia can be distinguished from brief psychotic disorder and psychotic disorder not otherwise specified. These findings may fuel the actual DSM-V discussion.
- Published
- 2011