1. Exploring clinical, echocardiographic and molecular biomarkers to predict bronchopulmonary dysplasia.
- Author
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Maria Alvarez-Fuente, Laura Moreno, Paloma Lopez-Ortego, Luis Arruza, Alejandro Avila-Alvarez, Marta Muro, Enrique Gutierrez, Carlos Zozaya, Gema Sanchez-Helguera, Dolores Elorza, Andrea Martinez-Ramas, Gema Villar, Carlos Labrandero, Lucia Martinez, Teresa Casado, Irene Cuadrado, and Maria Jesus Del Cerro
- Subjects
Medicine ,Science - Abstract
INTRODUCTION:Bronchopulmonary dysplasia (BPD) is the most common chronic lung disease in childhood, related to prematurity, and the most common cause of pulmonary hypertension (PH) secondary to pulmonary disease in children. Moderate and severe BPD have a worse outcome and relate more frequently with PH. The prediction of moderate or severe BPD development in extremely premature newborns is vital to implement preventive strategies. Starting with the hypothesis that molecular biomarkers were better than clinical and echocardiographic factors, this study aims to explore the ability of clinical, echocardiographic and analytical variables to predict moderate or severe BPD in a cohort of extremely preterm infants. PATIENTS AND METHODS:We designed a prospective longitudinal study, in which we followed a cohort of preterm newborns (gestational age
- Published
- 2019
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