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3. Contributors

Author

Ackland, Gareth L., primary, Ahmed, Adeel Rafi, additional, Annane, Djillali, additional, Ansari, Eman, additional, Axer, Hubertus, additional, Bakker, Jan, additional, Barbash, Ian J., additional, Bates, John James, additional, Bauer, Michael, additional, Bellinghausen, Amy L., additional, Bender, William S., additional, Biery, Matthew R., additional, Binnie, Alexandra, additional, Bleck, Thomas P., additional, Boncyk, Christina, additional, Brainard, Jason C., additional, Brakenridge, Scott C., additional, Brunkhorst, Frank Martin, additional, BSc(Physio), Tara Cahill,, additional, Campbell, Christina, additional, Casey, Jonathan Dale, additional, Cavaillon, Jean-Marc, additional, Cereda, Maurizio, additional, Cooper, David J., additional, Coopersmith, Craig M., additional, Cruz, Jennifer, additional, Cunha, Cheston B., additional, Curley, Gerard F., additional, Dalton, Allison, additional, Backer, Daniel De, additional, Deutschman, Clifford S., additional, Devlin, David, additional, Dos, Claudia C., additional, Drabek, Tomas, additional, Dragoi, Laura, additional, Dres, Martin, additional, Drewry, Anne M., additional, Duff, Stephen, additional, Efron, Philip A., additional, MB, Sinéad Egan,, additional, El, Ali A., additional, Ely, E. Wesley, additional, Evans, Laura, additional, Falco-Walter, Jessica, additional, Frogel, Jonathan K., additional, Ferguson, Niall D., additional, Fernandez-Moure, Joseph S., additional, Furmaga, Jakub, additional, Gaieski, David Foster, additional, Gajic, Ognjen, additional, De, Alice Gallo, additional, Genga, Kelly R., additional, Geoghegan, Pierce, additional, Giamarellos-Bourboulis, Evangelos J., additional, Gill, Rick, additional, Goligher, Ewan C., additional, Gordon, Emily K., additional, Grabenkort, W. Robert, additional, Gupta, Garima, additional, Gutsche, Jacob T., additional, Guven, Goksel, additional, Guyatt, Paige, additional, Heming, Nicholas, additional, Hendrix, Cheralyn J., additional, Hollen, McKenzie K., additional, Hollenberg, Steven M., additional, Tuan Ha, Vivien Hong, additional, Horie, Shahd, additional, Hough, Catherine L., additional, Ince, Can, additional, Iwashyna, Theodore J., additional, Jacobi, Judith, additional, Jeschke, Marc, additional, Johnson, Nicholas J., additional, Kahn, Jeremy M., additional, Kaplan, Lewis J., additional, Keegan, Mark T., additional, Kempker, Jordan Anthony, additional, Kevin, Leo G., additional, Khan, Yasin A., additional, Kleinpell, Ruth, additional, Kleinschmidt, Kurt, additional, Klompas, Michael, additional, Kochanek, Patrick M., additional, Kofke, W. Andrew, additional, Kohl, Benjamin, additional, Kortgen, Andreas, additional, Kung, David, additional, Laffey, John G., additional, Lage, Joel, additional, Lappin, David William, additional, Lamontagne, Francois, additional, Leisman, Daniel E., additional, Leong, Ron, additional, Levine, Joshua M., additional, Levinson, Andrew T., additional, Levy, Mitchell M., additional, Lewis, Ariane, additional, Slavin, Ariel Tamara, additional, Lheureux, Olivier, additional, Liu, Vincent X., additional, Lyons, Craig, additional, Maley, Jason H., additional, Malhotra, Atul, additional, Marks, Joshua A., additional, Martin, Greg S., additional, Martin, Niels D., additional, Masterson, Claire, additional, Mayasi, Yunis, additional, Maxime, Virginie, additional, McNicholas, Bairbre Aine, additional, McSparron, Jakob, additional, Meade, Maureen O., additional, Mikkelsen, Mark E., additional, Mohr, Alicia M., additional, Moran, Peter, additional, Moss, Stephanie Royer, additional, Murray, Patrick T., additional, Neligan, Patrick J., additional, Nguyen, Larry X., additional, Nichol, Alistair D., additional, Nugent, Katherine Lyn, additional, Nunnally, Mark E., additional, O’Connor, Michael F., additional, Odeyemi, Yewande, additional, Opal, Steven M., additional, O’Regan, Anthony, additional, O’Regan, John, additional, O’Shaughnessy, Michelle, additional, Owens, Robert L., additional, Pandharipande, Pratik, additional, Peltan, Ithan D., additional, Perner, Anders, additional, Pinsky, Michael R., additional, Piper, Greta, additional, Plante, Lauren A., additional, Pratzer, Ariella, additional, Preiser, Jean-Charles, additional, Prescott, Hallie C., additional, Quintana, Megan T., additional, Raab, Lindsay, additional, Radowsky, Jason S., additional, Raiten, Jesse M., additional, G. Reidy, Bryan T., additional, Reilly, Patrick M., additional, Remy, Kenneth E., additional, Rezoagli, Emanuele, additional, Ricci, Zaccaria, additional, Rivas, Lisbi, additional, Rochwerg, Bram, additional, Rock, Kristen Carey, additional, Ronco, Claudio, additional, Russell, James A., additional, Sandsmark, Danielle K., additional, Santos, Joshua Iokepa, additional, Sarani, Babak, additional, Scales, Damon C., additional, Scully, Michael, additional, Sevransky, Jon, additional, Shemie, Sam D., additional, Sims, Carrie A., additional, Smith, Brian P., additional, Spelde, Audrey E., additional, Stevens, Robert David, additional, Thompson, B. Taylor, additional, Tisherman, Samuel A., additional, Trinder, Mark, additional, Turnbull, Isaiah R., additional, MBBS, Ida-Fong Ukor,, additional, der Poll, Tom van, additional, van Engelen, Tjitske S.R., additional, Vasquez, Charles R., additional, Vella, Michael A., additional, Vernick, William J., additional, Villa, Gianluca, additional, Vincent, Jean-Louis, additional, Walker, Amy C., additional, Walley, Keith R., additional, Ware, Lorraine B., additional, Weiss, Stuart J., additional, Garcia, Anna E., additional, and Whyte, Pauline, additional

Published
2020
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6. Contributors

Author

Albright, Robert C., primary, Amerling, Richard, additional, Angeli, Paolo, additional, Angelotti, Maria Lucia, additional, Antonelli, Massimo, additional, Antoniotti, Riccardo, additional, Arulkumaran, Nishkantha, additional, Asfar, Pierre, additional, Ash, Stephen R., additional, Aucella, Filippo, additional, Aucella, Francesco, additional, Ave, Samuele, additional, Bagshaw, Sean M., additional, Balaraman, Vasanthi, additional, Baldwin, Ian, additional, Bargman, Joanne M., additional, Barletta, Gina-Marie, additional, Barletta, Jeffrey F., additional, Barnela, Shriganesh R., additional, Bayır, Hülya, additional, Beaulieu, Monica, additional, Bellasi, Antonio, additional, Bellomo, Rinaldo, additional, Beloncle, François, additional, Bhansali, Arjun, additional, Bihorac, Azra, additional, Billings, Frederic T., additional, Birk, Horst-Walter, additional, Bonilla-Reséndiz, Luis Ignacio, additional, Bouchard, Josée, additional, Bourke, Edmund, additional, Braitberg, George, additional, Brendolan, Alessandra, additional, Brocca, Alessandra, additional, Brophy, Patrick D., additional, Bucala, Richard, additional, Bunchman, Timothy E., additional, Burdmann, Emmanuel A., additional, Busse, Laurence W., additional, Caires, Renato Antunes, additional, Caironi, Pietro, additional, Camilla, Roberta, additional, Campos, Israel, additional, Canaud, Bernard, additional, Cantaluppi, Vincenzo, additional, Martinez, Maria P., additional, Capasso, Giovambattista, additional, Carcillo, Joseph A., additional, Carlesso, Eleonora, additional, Casino, Francesco G., additional, Castellano, Giuseppe, additional, Catania, Matteo, additional, Cawcutt, Kelly A., additional, Cerda, Jorge, additional, Charen, Elliot, additional, Chawla, Lakhmir S., additional, Chiaramonte, Stefano, additional, Chua, Horng-Ruey, additional, Cianciaruso, Bruno, additional, Ciceri, Paola, additional, Cieslak, Jacek, additional, Clark, William R., additional, Claure-Del Granado, Rolando, additional, Clementi, Anna, additional, Co, Ivan N., additional, Coelho, Fernanda Oliveira, additional, Conte, Ferruccio, additional, Corey, Howard E., additional, Cosmai, Laura, additional, Costalonga, Elerson Carlos, additional, Costamagna, Andrea, additional, Costanzo, Maria Rosa, additional, Cozzolino, Mario, additional, Cramer, Carl H., additional, Cravedi, Paolo, additional, Crepaldi, Carlo, additional, Creteur, Jacques, additional, Crew, R. John, additional, da Costa e Silva, Verônica Torres, additional, Davenport, Andrew, additional, Davies, Andrew R., additional, D'Costa, Rohit, additional, Dean, Dawson F., additional, Debiais, Charlotte, additional, de Cal, Massimo, additional, Dedhia, Paras, additional, de Grooth, Harm-Jan, additional, Dell'Aquila, Roberto, additional, Dellepiane, Sergio, additional, Dellinger, Richard Phillip, additional, Del Vecchio, Lucia, additional, Depner, Thomas A., additional, De Rosa, Silvia, additional, Deutschman, Clifford S., additional, Devarajan, Prasad, additional, Dewitte, A., additional, Di Iorio, Biagio R., additional, Di Lullo, Luca, additional, Di Micco, Lucia, additional, Di Nardo, Matteo, additional, Ding, Xiaoqiang, additional, D'Ippoliti, Fiorella, additional, Di Somma, Salvatore, additional, Doi, Kent, additional, Dries, David J., additional, Druml, Wilfred, additional, Duke, Graeme, additional, Durand, Francois, additional, Eadon, Michael T., additional, Eckstein, Devin, additional, Egi, Moritoki, additional, Eiam-Ong, Somchai, additional, Elbers, Paul W.G., additional, Elli, Francesca, additional, Elliott, Steve, additional, Emlet, David R., additional, Endre, Zoltan, additional, Evans, Roger G., additional, Fanelli, Vito, additional, Fattahi, Fatemeh, additional, Federspiel, Christine Kinggaard, additional, Ferrada, Marcela A., additional, Ferrari, Fiorenza, additional, Fiaccadori, Enrico, additional, Fiorentino, Marco, additional, Fisher, Caleb, additional, Flessner, Michael F., additional, Formica, Marco, additional, Forni, Lui G., additional, Francoz, Claire, additional, French, Craig, additional, Fuhrman, Dana Y., additional, Fumagalli, Giordano, additional, Galbusera, Miriam, additional, Gallieni, Maurizio, additional, Gammill, Hilary S., additional, Gao, Dayong, additional, Garzotto, Francesco, additional, Gatta, Giuseppe, additional, Genga, Kelly R., additional, Genovesi, Simonetta, additional, Genyk, Yuri S., additional, Geradin, Christel, additional, Gesualdo, Loreto, additional, Giavarina, Davide, additional, Giuliani, Anna, additional, Glezerman, Ilya G., additional, Goldstein, Stuart L., additional, Golper, Thomas A., additional, Gómez, Hernando, additional, Granata, Antonio, additional, Grandaliano, Giuseppe, additional, Grasselli, Giacomo, additional, Groeneveld, A.B. Johan, additional, Guerci, Philippe, additional, Gunnerson, Kyle J., additional, Harbord, Nikolas, additional, Harshman, Lyndsay A., additional, Hennessy, Anthony J., additional, Hill, Graham L., additional, Hobson, Charles, additional, Hohenstein, Bernd, additional, Honoré, Patrick M., additional, Horwitz, Edward, additional, Hosseinian, Leila, additional, Hoste, Eric A.J., additional, House, Andrew A., additional, Humes, H. David, additional, Husain-Syed, Faeq, additional, Ince, Can, additional, Ing, Todd S., additional, Jacobs, Rita, additional, Jaswal, Dharmvir, additional, Jeyabalan, Arun, additional, Joannes-Boyau, Olivier, additional, Joannidis, Michael, additional, Joyce, Emily, additional, Kane-Gill, Sandra L., additional, Kaplan, Lewis J., additional, Kashani, Kianoush, additional, Katz, Nevin, additional, Kellum, John A., additional, Khanna, Ramesh, additional, Kim-Campbell, Nahmah, additional, King, Joshua D., additional, Kirwan, Christopher J., additional, Kiss, Joseph E., additional, Klein, David, additional, Kotanko, Peter, additional, Krediet, Raymond T., additional, Kuhlmann, Martin K., additional, Kuiper, Jan Willem, additional, Lachance, Philippe, additional, Lameire, Norbert, additional, Langer, Thomas, additional, Lankadeva, Yugeesh R., additional, Laurin, Louis-Philippe, additional, Lazzeri, Elena, additional, Leblanc, Martine, additional, Lefebvre, Joannie, additional, Lentini, Paolo, additional, Leray-Moragués, Hélène, additional, Levin, Adeera, additional, Lew, Susie Q., additional, Liapis, Helen, additional, Liu, Kathleen D., additional, Livigni, Sergio, additional, Locatelli, Francesco, additional, Lorenzin, Anna, additional, Lu, Jian-Da, additional, Lu, Renhua, additional, Lysak, Nicholas, additional, Macedo, Etienne, additional, Madan, Niti, additional, Madore, François, additional, Maerz, Linda L., additional, Maiden, Matthew J., additional, Malhotra, Rakesh, additional, Marengo, Marita, additional, Mariano, Filippo, additional, Marik, Paul E., additional, Marini, John J., additional, Marino, Rossella, additional, Marshall, Mark R., additional, Mårtensson, Johan, additional, Matsuura, Ryo, additional, May, Clive N., additional, Mazzone, Patrizio, additional, McCauley, Jerry, additional, McCullough, Peter A., additional, McMahon, Blaithin A., additional, Mehta, Ravindra L., additional, Mele, Caterina, additional, Menon, Madhav, additional, Meola, Mario, additional, Mérouani, Aicha, additional, Meuwly, Jean-Yves, additional, Milla, Paola, additional, Misra, Madhukar, additional, Misra, Paraish S., additional, Mizock, Barry A., additional, Modi, Jwalant R., additional, Moeckel, Gilbert, additional, Molitoris, Bruce A., additional, Morabito, Santo, additional, Mucelli, Roberto Pozzi, additional, Murray, Patrick T., additional, Murugan, Raghavan, additional, Nadim, Mitra K., additional, Nair, Devika, additional, Nalesso, Federico, additional, Neri, Mauro, additional, Nguyen, Trung C., additional, Ni, Zhaohui, additional, Noris, Marina, additional, Novick, Tessa, additional, O'Horo, John C., additional, Okusa, Mark Douglas, additional, Opal, Steven M., additional, Opdam, Helen Ingrid, additional, Ostermann, Marlies, additional, Ottaviano, Emerenziana, additional, Oudemans-van Straaten, Heleen M., additional, Overgaard-Steensen, Christian, additional, Padalino, Massimo A., additional, Panichi, Vincenzo, additional, Parameswaran, Priyanka, additional, Patel, Samir S., additional, Payen, Didier, additional, Pea, Federico, additional, Peacock, W. Frank, additional, Peart, Sandrica Young, additional, Peerapornratana, Sadudee, additional, Pelosi, Paolo, additional, Peng, Zhi-Yong, additional, Perico, Norberto, additional, Peruzzi, Licia, additional, Pesce, Francesco, additional, Pesenti, Antonio, additional, Petrucci, Ilaria, additional, Pham, Phuong-Chi, additional, Pham, Phuong-Thu, additional, Phoon, Richard K.S., additional, Piano, Salvatore, additional, Pinsky, Michael R., additional, Piquilloud, Lise, additional, Pistolesi, Valentina, additional, Plank, Lindsay D., additional, Plötz, Frans B., additional, Podestá, Manuel Alfredo, additional, Porta, Camillo, additional, Pozzato, Marco, additional, Prencipe, Michele, additional, Prowle, John R., additional, Puthucheary, Zudin A., additional, Qu, Lirong, additional, Rachoin, Jean-Sebastien, additional, Radhakrishnan, Jai, additional, Ranieri, V. Marco, additional, Ratanarat, Ranistha, additional, Remuzzi, Giuseppe, additional, Resnick, Shelby, additional, Rewa, Oleksa G., additional, Ricci, Zaccaria, additional, Ridel, Christophe, additional, Rifai, Kinan, additional, Ring, Troels, additional, Rizo-Topete, Lilia M., additional, Roessler, Eric, additional, Romagnani, Paola, additional, Romagnoli, Stefano, additional, Ronco, Claudio, additional, Ronco, Federico, additional, Rosner, Mitchell H., additional, Rossetti, Emanuele, additional, Russell, James A., additional, Saab, Georges, additional, Sabatino, Alice, additional, Saboo, Sonali S., additional, Samoni, Sara, additional, Sappington, Penny Lynn, additional, Sartori, Marco, additional, Savige, Judy, additional, Schena, Francesco Paolo, additional, Schneider, Antoine Guillaume, additional, Schraverus, Pieter, additional, Schulte, Wibke, additional, Segoloni, Giuseppe, additional, Semler, Matthew W., additional, Sharma, Aashish, additional, Shaw, Andrew, additional, Sheth, Naitik, additional, Shukla, Ashutosh, additional, Siddall, Eric C., additional, Sievers, Theodore M., additional, Siew, Edward D., additional, Singbartl, Kai, additional, Singer, Mervyn, additional, Singh, Pooja, additional, Smith, Loren E., additional, Soni, Sachin S., additional, Soto, Mara Serrano, additional, Spapen, Herbert D., additional, Srisawat, Nattachai, additional, Srivastava, Ajay, additional, Stellin, Giovanni, additional, Symons, Jordan M., additional, Szamosfalvi, Balazs, additional, Tai, Kian Bun, additional, Takalkar, Unmesh V., additional, Teitelbaum, Isaac, additional, Tetta, Ciro, additional, Thakar, Charuhas V., additional, Tonon, Marta, additional, Trepiccione, Francesco, additional, Triulzi, Darrell, additional, Tushar, Chopra, additional, Uchino, Shigehiko, additional, Valika, Ali, additional, Van Biesen, Wim, additional, Vandenberghe, Wim, additional, Vanholder, Raymond, additional, Vanmassenhove, Jill, additional, Verbine, Anton, additional, Vergano, Marco, additional, Villa, Gianluca, additional, Villeneuve, Pierre-Marc, additional, Vincent, Jean-Louis, additional, Vinsonneau, Christophe, additional, Virzì, Grazia Maria, additional, Visconti, Federico, additional, Visvanathan, Ravindran, additional, Van Vong, Li, additional, Walmrath, Hans-Dieter, additional, Ward, Peter A., additional, Weir, Matthew A., additional, Wen, Xiaoyan, additional, Wendon, Julia, additional, Winchester, James Frank, additional, Wong, Adrian, additional, Woodhouse, Elke L., additional, Xue, Jun, additional, Yadav, Anju, additional, Yerram, Preethi, additional, Yessayan, Lenar, additional, Yeun, Jane Y., additional, Yu, Alex W., additional, Zaccaria, Marta, additional, Zacchia, Miriam, additional, Zachariah, Teena P., additional, Zamperetti, Nereo, additional, Zampieri, Fernando G., additional, Zanco, Pierluigi, additional, Zanella, Alberto, additional, Zanoli, Luca, additional, Zappitelli, Michael, additional, Zaragoza, Jose J., additional, Zarbock, Alexander, additional, Zaroccolo, Marta, additional, Zhang, Han, additional, and Zimmer, Andrea, additional

Published
2019
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13. Cholesteryl Ester Transfer Protein Influences High-Density Lipoprotein Levels and Survival in Sepsis

Author

Trinder, Mark, primary, Genga, Kelly R., additional, Kong, HyeJin Julia, additional, Blauw, Lisanne L., additional, Lo, Cody, additional, Li, Xuan, additional, Cirstea, Mihai, additional, Wang, Yanan, additional, Rensen, Patrick C. N., additional, Russell, James A., additional, Walley, Keith R., additional, Boyd, John H., additional, and Brunham, Liam R., additional

Published
2019
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15. Colaboradores

Author

Ackland, Gareth L., Ahmed, Adeel Rafi, Annane, Djillali, Ansari, Eman, Axer, Hubertus, Bakker, Jan, Barbash, Ian J., James Bates, John, Bauer, Michael, Bellinghausen, Amy L., Bender, William S., Biery, Matthew R., Binnie, Alexandra, Bleck, Thomas P., Boncyk, Christina, Brainard, Jason C., Brakenridge, Scott C., Brunkhorst, Frank Martin, Cahill, Tara, Campbell, Christina, Casey, Jonathan Dale, Cavaillon, Jean-Marc, Cereda, Maurizio, Cooper, David J., Coopersmith, Craig M., Cruz, Jennifer, Cunha, Cheston B., Curley, Gerard F., Dalton, Allison, Backer, Daniel De, Deutschman, Clifford S., Devlin, David, Dos Santos, Claudia C., Drabek, Tomas, Dragoi, Laura, Dres, Martin, Drewry, Anne M., Duff, Stephen, Efron, Philip A., Egan, Sinéad, El Solh, Ali A., Ely, E. Wesley, Evans, Laura, Falco-Walter, Jessica, Frogel, Jonathan K., Ferguson, Niall D., Fernandez-Moure, Joseph S., Furmaga, Jakub, Gaieski, David Foster, Gajic, Ognjen, De Moraes, Alice Gallo, Genga, Kelly R., Geoghegan, Pierce, Giamarellos-Bourboulis, Evangelos J., Gill, Rick, Goligher, Ewan C., Gordon, Emily K., Grabenkort, W. Robert, Gupta, Garima, Gutsche, Jacob T., Guven, Goksel, Guyatt, Paige, Heming, Nicholas, Hendrix, Cheralyn J., Hollen, McKenzie K., Hollenberg, Steven M., Ha, Vivien Hong Tuan, Horie, Shahd, Hough, Catherine L., Ince, Can, Iwashyna, Theodore J., Jacobi, Judith, Jeschke, Marc, Johnson, Nicholas J., Kahn, Jeremy M., Kaplan, Lewis J., Keegan, Mark T., Kempker, Jordan Anthony, Kevin, Leo G., Khan, Yasin A., Kleinpell, Ruth, Kleinschmidt, Kurt, Klompas, Michael, Kochanek, Patrick M., Kofke, W. Andrew, Kohl, Benjamin, Kortgen, Andreas, Kung, David, Laffey, John G., Lage, Joel, Lappin, David William, Lamontagne, Francois, Leisman, Daniel E., Leong, Ron, Levine, Joshua M., Levinson, Andrew T., Levy, Mitchell M., Lewis, Ariane, Slavin, Ariel Tamara, Lheureux, Olivier, Liu, Vincent X., Lyons, Craig, Maley, Jason H., Malhotra, Atul, Marks, Joshua A., Martin, Greg S., Martin, Niels D., Masterson, Claire, Mayasi, Yunis, Maxime, Virginie, McNicholas, Bairbre Aine, McSparron, Jakob, Meade, Maureen O., Mikkelsen, Mark E., Mohr, Alicia M., Moran, Peter, Moss, Stephanie Royer, Murray, Patrick T., Neligan, Patrick J., Nguyen, Larry X., Nichol, Alistair D., Nugent, Katherine Lyn, Nunnally, Mark E., O’Connor, Michael F., Odeyemi, Yewande, Opal, Steven M., O’Regan, Anthony, O’Regan, John, O’Shaughnessy, Michelle, Owens, Robert L., Pandharipande, Pratik, Peltan, Ithan D., Perner, Anders, Pinsky, Michael R., Piper, Greta, Plante, Lauren A., Pratzer, Ariella, Preiser, Jean-Charles, Prescott, Hallie C., Quintana, Megan T., Raab, Lindsay, Radowsky, Jason S., Raiten, Jesse M., Reidy, Bryan T.G., Reilly, Patrick M., Remy, Kenneth E., Rezoagli, Emanuele, Ricci, Zaccaria, Rivas, Lisbi, Rochwerg, Bram, Rock, Kristen Carey, Ronco, Claudio, Russell, James A., Sandsmark, Danielle K., Santos, Joshua Iokepa, Sarani, Babak, Scales, Damon C., Scully, Michael, Sevransky, Jon, Shemie, Sam D., Sims, Carrie A., Smith, Brian P., Spelde, Audrey E., Stevens, Robert David, Thompson, B. Taylor, Tisherman, Samuel A., Trinder, Mark, Turnbull, Isaiah R., Ukor, Ida-Fong, van der Poll, Tom, van Engelen, Tjitske S.R., Vasquez, Charles R., Vella, Michael A., Vernick, William J., Villa, Gianluca, Vincent, Jean-Louis, Walker, Amy C., Walley, Keith R., Ware, Lorraine B., Weiss, Stuart J., Garcia Whitlock, Anna E., and Whyte, Pauline

Published
2021
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16. Colaboradores

Author

Albright, Robert C., Amerling, Richard, Angeli, Paolo, Lucia Angelotti, Maria, Antonelli, Massimo, Antoniotti, Riccardo, Arulkumaran, Nishkantha, Asfar, Pierre, Ash, Stephen R., Aucella, Filippo, Aucella, Francesco, Ave, Samuele, Bagshaw, Sean M., Balaraman, Vasanthi, Baldwin, Ian, Bargman, Joanne M., Barletta, Gina-Marie, Barletta, Jeffrey F., Barnela, Shriganesh R., Bayır, Hülya, Beaulieu, Monica, Bellasi, Antonio, Bellomo, Rinaldo, Beloncle, François, Bhansali, Arjun, Bihorac, Azra, Billings, Frederic T., Birk, Horst-Walter, Bonilla-Reséndiz, Luis Ignacio, Bouchard, Josée, Bourke, Edmund, Braitberg, George, Brendolan, Alessandra, Brocca, Alessandra, Brophy, Patrick D., Bucala, Richard, Bunchman, Timothy E., Burdmann, Emmanuel A., Busse, Laurence W., Antunes Caires, Renato, Caironi, Pietro, Camilla, Roberta, Campos, Israel, Canaud, Bernard, Cantaluppi, Vincenzo, Martinez Cantarin, Maria P., Capasso, Giovambattista, Carcillo, Joseph A., Carlesso, Eleonora, Casino, Francesco G., Castellano, Giuseppe, Catania, Matteo, Cawcutt, Kelly A., Cerda, Jorge, Charen, Elliot, Chawla, Lakhmir S., Chiaramonte, Stefano, Chua, Horng-Ruey, Cianciaruso, Bruno, Ciceri, Paola, Cieslak, Jacek, Clark, William R., Claure-Del Granado, Rolando, Clementi, Anna, Co, Ivan N., Oliveira Coelho, Fernanda, Conte, Ferruccio, Corey, Howard E., Cosmai, Laura, Carlos Costalonga, Elerson, Costamagna, Andrea, Rosa Costanzo, Maria, Cozzolino, Mario, Cramer, Carl H., Cravedi, Paolo, Crepaldi, Carlo, Creteur, Jacques, John Crew, R., Torres da Costa Silva, Verônica, Davenport, Andrew, Davies, Andrew R., D’Costa, Rohit, Dean, Dawson F., Debiais, Charlotte, de Cal, Massimo, Dedhia, Paras, de Grooth, Harm-Jan, Dell’Aquila, Roberto, Dellepiane, Sergio, Phillip Dellinger, Richard, Del Vecchio, Lucia, Depner, Thomas A., De Rosa, Silvia, Deutschman, Clifford S., Devarajan, Prasad, Dewitte, A., Di Iorio, Biagio R., Di Lullo, Luca, Di Micco, Lucia, Di Nardo, Matteo, Ding, Xiaoqiang, D’Ippoliti, Fiorella, Di Somma, Salvatore, Doi, Kent, Dries, David J., Druml, Wilfred, Duke, Graeme, Durand, Francois, Eadon, Michael T., Eckstein, Devin, Egi, Moritoki, Eiam-Ong, Somchai, Elbers, Paul W.G., Elli, Francesca, Elliott, Steve, Emlet, David R., Endre, Zoltan, Evans, Roger G., Fanelli, Vito, Fattahi, Fatemeh, Kinggaard Federspiel, Christine, Ferrada, Marcela A., Ferrari, Fiorenza, Fiaccadori, Enrico, Fiorentino, Marco, Fisher, Caleb, Flessner, Michael F., Formica, Marco, Forni, Lui G., Francoz, Claire, French, Craig, Fuhrman, Dana Y., Fumagalli, Giordano, Galbusera, Miriam, Gallieni, Maurizio, Gammill, Hilary S., Gao, Dayong, Garzotto, Francesco, Gatta, Giuseppe, Genga, Kelly R., Genovesi, Simonetta, Genyk, Yuri S., Geradin, Christel, Gesualdo, Loreto, Giavarina, Davide, Giuliani, Anna, Glezerman, Ilya G., Goldstein, Stuart L., Golper, Thomas A., Gómez, Hernando, Granata, Antonio, Grandaliano, Giuseppe, Grasselli, Giacomo, Johan Groeneveld, A.B., Guerci, Philippe, Gunnerson, Kyle J., Harbord, Nikolas, Harshman, Lyndsay A., Hennessy, Anthony J., Hill, Graham L., Hobson, Charles, Hohenstein, Bernd, Honoré, Patrick M., Horwitz, Edward, Hosseinian, Leila, Hoste, Eric A.J., House, Andrew A., David Humes, H., Husain-Syed, Faeq, Ince, Can, Ing, Todd S., Jacobs, Rita, Jaswal, Dharmvir, Jeyabalan, Arun, Joannes-Boyau, Olivier, Joannidis, Michael, Joyce, Emily, Kane-Gill, Sandra L., Kaplan, Lewis J., Kashani, Kianoush, Katz, Nevin, Kellum, John A., Khanna, Ramesh, Kim-Campbell, Nahmah, King, Joshua D., Kirwan, Christopher J., Kiss, Joseph E., Klein, David, Kotanko, Peter, Krediet, Raymond T., Kuhlmann, Martin K., Willem Kuiper, Jan, Lachance, Philippe, Lameire, Norbert, Langer, Thomas, Lankadeva, Yugeesh R., Laurin, Louis-Philippe, Lazzeri, Elena, Leblanc, Martine, Lefebvre, Joannie, Lentini, Paolo, Leray-Moragués, Hélène, Levin, Adeera, Lew, Susie Q., Liapis, Helen, Liu, Kathleen D., Livigni, Sergio, Locatelli, Francesco, Lorenzin, Anna, Lu, Jian-Da, Lu, Renhua, Lysak, Nicholas, Macedo, Etienne, Madan, Niti, Madore, François, Maerz, Linda L., Maiden, Matthew J., Malhotra, Rakesh, Marengo, Marita, Mariano, Filippo, Marik, Paul E., Marini, John J., Marino, Rossella, Marshall, Mark R., Mårtensson, Johan, Matsuura, Ryo, May, Clive N., Mazzone, Patrizio, McCauley, Jerry, McCullough, Peter A., McMahon, Blaithin A., Mehta, Ravindra L., Mele, Caterina, Menon, Madhav, Meola, Mario, Mérouani, Aicha, Meuwly, Jean-Yves, Milla, Paola, Misra, Madhukar, Misra, Paraish S., Mizock, Barry A., Modi, Jwalant R., Moeckel, Gilbert, Molitoris, Bruce A., Morabito, Santo, Pozzi Mucelli, Roberto, Murray, Patrick T., Murugan, Raghavan, Nadim, Mitra K., Nair, Devika, Nalesso, Federico, Neri, Mauro, Nguyen, Trung C., Ni, Zhaohui, Noris, Marina, Novick, Tessa, O’Horo, John C., Douglas Okusa, Mark, Opal, Steven M., Ingrid Opdam, Helen, Ostermann, Marlies, Ottaviano, Emerenziana, Oudemans-van Straaten, Heleen M., Overgaard-Steensen, Christian, Padalino, Massimo A., Panichi, Vincenzo, Parameswaran, Priyanka, Patel, Samir S., Payen, Didier, Pea, Federico, Frank Peacock, W., Young Peart, Sandrica, Peerapornratana, Sadudee, Pelosi, Paolo, Peng, Zhi-Yong, Perico, Norberto, Peruzzi, Licia, Pesce, Francesco, Pesenti, Antonio, Petrucci, Ilaria, Pham, Phuong-Chi, Pham, Phuong-Thu, Phoon, Richard K.S., Piano, Salvatore, Pinsky, Michael R., Piquilloud, Lise, Pistolesi, Valentina, Plank, Lindsay D., Plötz, Frans B., Alfredo Podestá, Manuel, Porta, Camillo, Pozzato, Marco, Prencipe, Michele, Prowle, John R., Puthucheary, Zudin A., Qu, Lirong, Rachoin, Jean-Sebastien, Radhakrishnan, Jai, Marco Ranieri, V., Ratanarat, Ranistha, Remuzzi, Giuseppe, Resnick, Shelby, Rewa, Oleksa G., Ricci, Zaccaria, Ridel, Christophe, Rifai, Kinan, Ring, Troels, Rizo-Topete, Lilia M., Roessler, Eric, Romagnani, Paola, Romagnoli, Stefano, Ronco, Claudio, Ronco, Federico, Rosner, Mitchell H., Rossetti, Emanuele, Russell, James A., Saab, Georges, Sabatino, Alice, Saboo, Sonali S., Samoni, Sara, Lynn Sappington, Penny, Sartori, Marco, Savige, Judy, Paolo Schena, Francesco, Guillaume Schneider, Antoine, Schraverus, Pieter, Schulte, Wibke, Segoloni, Giuseppe, Semler, Matthew W., Sharma, Aashish, Shaw, Andrew, Sheth, Naitik, Shukla, Ashutosh, Siddall, Eric C., Sievers, Theodore M., Siew, Edward D., Singbartl, Kai, Singer, Mervyn, Singh, Pooja, Smith, Loren E., Soni, Sachin S., Serrano Soto, Mara, Spapen, Herbert D., Srisawat, Nattachai, Srivastava, Ajay, Stellin, Giovanni, Symons, Jordan M., Szamosfalvi, Balazs, Bun Tai, Kian, Takalkar, Unmesh V., Teitelbaum, Isaac, Tetta, Ciro, Thakar, Charuhas V., Tonon, Marta, Trepiccione, Francesco, Triulzi, Darrell, Tushar, Chopra, Uchino, Shigehiko, Valika, Ali, Van Biesen, Wim, Vandenberghe, Wim, Vanholder, Raymond, Vanmassenhove, Jill, Verbine, Anton, Vergano, Marco, Villa, Gianluca, Villeneuve, Pierre-Marc, Vincent, Jean-Louis, Vinsonneau, Christophe, Maria Virzì, Grazia, Visconti, Federico, Visvanathan, Ravindran, Van Vong, Li, Walmrath, Hans-Dieter, Ward, Peter A., Weir, Matthew A., Wen, Xiaoyan, Wendon, Julia, Frank Winchester, James, Wong, Adrian, Woodhouse, Elke L., Xue, Jun, Yadav, Anju, Yerram, Preethi, Yessayan, Lenar, Yeun, Jane Y., Yu, Alex W., Zaccaria, Marta, Zacchia, Miriam, Zachariah, Teena P., Zamperetti, Nereo, Zampieri, Fernando G., Zanco, Pierluigi, Zanella, Alberto, Zanoli, Luca, Zappitelli, Michael, Zaragoza, Jose J., Zarbock, Alexander, Zaroccolo, Marta, Zhang, Han, and Zimmer, Andrea

Published
2020
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18. Survival benefit of a low ratio of visceral to subcutaneous adipose tissue depends on LDL clearance versus production in sepsis

Author

Lee, Joseph G H, Genga, Kelly R, Pisitsak, Chawika, Boyd, John H, Leung, Alex K K, Russell, James A, and Walley, Keith R

Subjects
nutritional and metabolic diseases, lipids (amino acids, peptides, and proteins), 3. Good health
Abstract

Background: Patients with sepsis with a high ratio of visceral adipose tissue (VAT) to subcutaneous adipose tissue (SAT) have increased mortality. Our goal was to investigate the mechanism of this effect, noting that low LDL levels are also associated with increased sepsis mortality. Accordingly we tested for association between VAT/SAT, low-density lipoprotein (LDL) levels, and mortality. Then we examined the effect of statin treatment, which decreases LDL production, and the effect of PCSK9 genotype, which increases LDL clearance. Methods: We performed retrospective analysis of a cohort of patients with sepsis from a tertiary care adult intensive care unit in Vancouver, Canada, who underwent abdominal computed tomography (CT) (n = 75) for clinical reasons. We compared LDL levels in patients with sepsis according to high versus low VAT/SAT and 90-day survival. We next examined the effects of statin therapy and PCSK9 loss-of-function genotype on survival. Results: Patients with a low VAT/SAT had increased 90-day survival and were relatively protected against low LDL levels in sepsis compared to high VAT/SAT. Statin treatment abrogated the beneficial effects of low VAT/SAT; eliminating the difference in LDL levels and survival between patients with low and high VAT/SAT. PSCK9 loss-of-function genotype similarly eliminated the increased LDL levels in low VAT/SAT patients but, in contrast, increased the survival advantage of low VAT/SAT compared to high VAT/SAT. Conclusions: Low LDL levels per se are not simply associated with decreased sepsis survival because lowering LDL levels by inhibiting LDL production (statin treatment) is associated with adverse outcomes, while increased LDL clearance (PCSK9 loss-of-function genotype) is associated with improved outcomes in patients with low VAT/SAT.

19. Cholesteryl Ester Transfer Protein Influences High-Density Lipoprotein Levels and Survival in Sepsis.

Author

Trinder, Mark, Genga, Kelly R, Kong, HyeJin Julia, Blauw, Lisanne L, Lo, Cody, Li, Xuan, Cirstea, Mihai, Wang, Yanan, Rensen, Patrick C N, Russell, James A, Walley, Keith R, Boyd, John H, and Brunham, Liam R

Abstract

Rationale: High-density lipoprotein (HDL) cholesterol (HDL-C) levels decline during sepsis, and lower levels are associated with worse survival. However, the genetic mechanisms underlying changes in HDL-C during sepsis, and whether the relationship with survival is causative, are largely unknown.Objectives: We hypothesized that variation in genes involved in HDL metabolism would contribute to changes in HDL-C levels and clinical outcomes during sepsis.Methods: We performed targeted resequencing of HDL-related genes in 200 patients admitted to an emergency department with sepsis (Early Infection cohort). We examined the association of genetic variants with HDL-C levels, 28-day survival, 90-day survival, organ dysfunction, and need for vasopressor or ventilatory support. Candidate variants were further assessed in the VASST (Vasopressin versus Norepinephrine Infusion in Patients with Septic Shock Trial) cohort (n = 632) and St. Paul's Hospital Intensive Care Unit 2 (SPHICU2) cohort (n = 203).Measurements and Main Results: We identified a rare missense variant in CETP (cholesteryl ester transfer protein gene; rs1800777-A) that was associated with significant reductions in HDL-C levels during sepsis. Carriers of the A allele (n = 10) had decreased survival, more organ failure, and greater need for organ support compared with noncarriers. We replicated this finding in the VASST and SPHICU2 cohorts, in which carriers of rs1800777-A (n = 35 and n = 12, respectively) had significantly reduced 28-day survival. Mendelian randomization was consistent with genetically reduced HDL levels being a causal factor for decreased sepsis survival.Conclusions: Our results identify CETP as a critical regulator of HDL levels and clinical outcomes during sepsis. These data point toward a critical role for HDL in sepsis. [ABSTRACT FROM AUTHOR]

Published
2018
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