184 results on '"Genovese, Pietro"'
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2. IL-12 reprograms CAR-expressing natural killer T cells to long-lived Th1-polarized cells with potent antitumor activity
3. Epitope editing enables targeted immunotherapy of acute myeloid leukaemia
4. Base Editing of Human Hematopoietic Stem Cells
5. Enhancing prime editing in hematopoietic stem and progenitor cells by modulating nucleotide metabolism
6. TIM-3, LAG-3, or 2B4 gene disruptions increase the anti-tumor response of engineered T cells
7. Exonic knockout and knockin gene editing in hematopoietic stem and progenitor cells rescues RAG1 immunodeficiency
8. Retrieval of vector integration sites from cell-free DNA
9. BAR-Seq clonal tracking of gene-edited cells
10. Epitope Edited Hematopoietic Stem Cells Allow Immune-Based In Vivo Selection of Genome-Engineered Cells
11. Efficient gene editing of human long-term hematopoietic stem cells validated by clonal tracking
12. NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease
13. Therapeutic gene editing in CD34+ hematopoietic progenitors from Fanconi anemia patients
14. Mesenchymal stromal cells improve the transplantation outcome of CRISPR-Cas9 gene-edited human HSPCs
15. Epitope Engineered Hematopoietic Stem and Progenitor Cells to Enable CAR-T Cell Immunotherapy for Acute Myeloid Leukemia
16. Septin-6 Regulates Murine and Human Hematopoiesis, and Its Dysregulation Is Associated with Pediatric Myelodysplasia
17. Real life hexavalent vaccination among children as a practical guide for public health professionals: Four years (from 2016 to 2019) of clinical practice in Sicily, Italy
18. Therapeutic gene editing of T cells to correct CTLA-4 insufficiency
19. Mesenchymal stromal cells improve the transplantation outcome of CRISPR-Cas9 gene-edited human HSPCs
20. Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1
21. CD44v6-targeted T cells mediate potent antitumor effects against acute myeloid leukemia and multiple myeloma
22. Towards Clinical Translation of Hematopoietic Cell Gene Editing for Treating Hyper-IgM Type 1
23. Targeted genome editing in human repopulating haematopoietic stem cells
24. Editorial: Mutation-Specific Gene Editing for Blood Disorders
25. Epitope Edited Hematopoietic Stem Cells to Enable Synergistic Immunotherapy Combinations for Acute Myeloid Leukemia
26. The Association of SEPTIN6 Mutations with Pediatric Myelodysplasia
27. Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer
28. Targeted gene therapy and cell reprogramming in Fanconi anemia
29. Gene Editing of Hematopoietic Stem Cells: Hopes and Hurdles Toward Clinical Translation
30. Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper‐IgM syndrome
31. Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk
32. Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response
33. Cyclosporine H Overcomes Innate Immune Restrictions to Improve Lentiviral Transduction and Gene Editing In Human Hematopoietic Stem Cells
34. Generation of Memory Stem T Cells Specific for Tumor Antigens and Resistant to Inhibitory Signals By Genome Editing
35. Therapeutic gene editing in CD 34 + hematopoietic progenitors from Fanconi anemia patients
36. The Association of SEPTIN6Mutations with Pediatric Myelodysplasia
37. 130. Purification of Large Scale mRNA Encoding ZFN Nucleases by dHPLC Technology
38. 37. Towards Clinical Translation of Hematopoietic Stem Cell Gene Editing for the Correction of SCID-X1 Mutations
39. 42. Correction of SCID-X1 by Targeted Genome Editing of Hematopoietic Stem/Progenitor Cells (HSPC) in the Mouse Model
40. 752. Single Chain TCR Gene Editing in Adoptive Cell Therapy for Multiple Myeloma
41. Therapeutic gene editing in CD34+ hematopoietic progenitors from Fanconi anemia patients.
42. 481. Targeted Genome Editing in Mouse Hematopoietic Stem/Progenitor Cells (HSPC) To Model Gene Correction of SCID-X1
43. 716. Durable Acute Myeloid Leukemia Remission Without Myeloablation in an Innovative Xenotolerant Mouse Model of CD44v6 CAR-T Cell Immunotherapy
44. 209. TCR Gene Editing in a Single Step of T Cell Activation To Redirect T Cell Specificity and Prevent GvHD
45. 686. Gene Correction of IL2RG in Human Hematopoietic Stem and Progenitor Cells
46. Cytokine-Induced Killer Cells Engineered with Exogenous T-Cell Receptors Directed Against Melanoma Antigens: Enhanced Efficacy of Effector Cells Endowed with a Double Mechanism of Tumor Recognition
47. Integrase-Defective Lentiviral Vectors Enable Tolerogenic Expression of Bioactive Molecules in the Liver With Minimal Genotoxic Risk
48. NY-ESO-1 Single Edited T Cells to Treat Multiple Myeloma without Inducing GvHD
49. TCR Gene Editing Achieved In a Single Round Of T Cell Activation Is Sufficient To Redirect T Cell Specificity and Prevent GvHD
50. Off-Tumor Target Expression Levels Do Not Predict CAR-T Cell Killing: A Foundation For The Safety Of CD44v6-Targeted T Cells
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