370 results on '"Gheysens, O"'
Search Results
2. Perspectives on joint EANM/SNMMI/ANZSNM practice guidelines/procedure standards for [18F]FDG PET/CT imaging during immunomodulatory treatments in patients with solid tumors
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Lopci, E., Aide, N., Dimitrakopoulou-Strauss, A., Dercle, L., Iravani, A., Seban, R. D., Sachpekidis, C., Humbert, O., Gheysens, O., Glaudemans, A. W. J. M., Weber, W. A., Van den Abbeele, A. D., Wahl, R. L., Scott, A. M., Pandit-Taskar, N., and Hicks, R. J.
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- 2022
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- View/download PDF
3. Diagnostic value of [18F]FDG-PET/CT for treatment monitoring in large vessel vasculitis: a systematic review and meta-analysis
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van der Geest, K. S. M., Treglia, G., Glaudemans, A. W. J. M., Brouwer, E., Sandovici, M., Jamar, F., Gheysens, O., and Slart, R. H. J. A.
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- 2021
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4. Diagnostic value of [18F]FDG-PET/CT in polymyalgia rheumatica: a systematic review and meta-analysis
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van der Geest, K. S. M., Treglia, G., Glaudemans, A. W. J. M., Brouwer, E., Jamar, F., Slart, R. H. J. A., and Gheysens, O.
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- 2021
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5. Analysis of partial volume correction on quantification and regional heterogeneity in cardiac PET
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Turco, A., Nuyts, J., Duchenne, J., Gheysens, O., Voigt, J.U., Claus, P., and Vunckx, K.
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- 2020
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6. The value of 18F-FDG PET/CT for the diagnosis of device-related infections in patients with a left ventricular assist device: a systematic review and meta-analysis
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ten Hove, D., Treglia, G., Slart, R. H. J. A., Damman, K., Wouthuyzen-Bakker, M., Postma, D. F., Gheysens, O., Borra, R. J. H., Mecozzi, G., van Geel, P. P., Sinha, B., and Glaudemans, A. W. J. M.
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- 2021
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7. Prognostic superiority of International Prognostic Index over [18F]FDG PET/CT volumetric parameters in post-transplant lymphoproliferative disorder
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Montes de Jesus, F., Dierickx, D., Vergote, V., Noordzij, W., Dierckx, R. A. J. O., Deroose, C. M., Glaudemans, A. W. J. M., Gheysens, O., and Kwee, T. C.
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- 2021
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8. Partial volume and motion correction in cardiac PET: First results from an in vs ex vivo comparison using animal datasets
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Turco, A., Gheysens, O., Duchenne, J., Nuyts, J., Rega, F., Voigt, J.U., Vunckx, K., and Claus, P.
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- 2019
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9. Performance of advanced imaging modalities at diagnosis and treatment response evaluation of patients with post-transplant lymphoproliferative disorder: A systematic review and meta-analysis
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Montes de Jesus, F.M., Kwee, T.C., Nijland, M., Kahle, X.U., Huls, G., Dierckx, R.A.J.O., van Meerten, T., Gheysens, O., Dierickx, D., Vergote, V., Noordzij, W., and Glaudemans, A.W.J.M.
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- 2018
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10. Axillary staging for breast cancer during pregnancy: feasibility and safety of sentinel lymph node biopsy
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Han, S. N., Amant, F., Cardonick, E. H., Loibl, S., Peccatori, F. A., Gheysens, O., Sangalli, C. A., Nekljudova, V., Steffensen, K. Dahl, Mhallem Gziri, M., Schröder, C. P., Lok, C. A. R., Verest, A., Neven, P., Smeets, A., Pruneri, G., Cremonesi, M., Gentilini, O., and On behalf of the International Network on Cancer, Infertility and Pregnancy
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- 2018
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11. EBV-Positive and EBV-Negative Posttransplant Diffuse Large B Cell Lymphomas Have Distinct Genomic and Transcriptomic Features
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Finalet Ferreiro, J., Morscio, J., Dierickx, D., Vandenberghe, P., Gheysens, O., Verhoef, G., Zamani, M., Tousseyn, T., and Wlodarska, I.
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- 2016
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12. A role of FDG PET/CT for Response Assessment in Large Vessel Disease?
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Treglia, G., Albano, D., Dondi, F., Bertagna, F., and Gheysens, O.
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Humans ,Fluorodeoxyglucose F18 ,Positron Emission Tomography Computed Tomography/methods ,Positron-Emission Tomography ,Vasculitis ,Radiopharmaceuticals - Abstract
Currently, a large amount of evidence-based data clearly demonstrates the usefulness of [ 18 F]FDG PET/CT in the diagnosis of several infectious and inflammatory diseases, including those related to the large vessels. The aim of this article is to clarify whether, beyond initial diagnosis, [ 18 F]FDG PET/CT may have a role in treatment response assessment in inflammatory or infectious diseases of the large vessels, including large vessel vasculitis, vascular graft infection, retroperitoneal fibrosis/chronic periaortitis and infective native aortic aneurysms. Rapidly accumulating data suggest that [ 18 F]FDG PET/CT could be a valuable imaging method for therapy monitoring in some infectious and inflammatory diseases of large vessels. The available data, albeit preliminary, indicate that [ 18 F]FDG PET/CT could even play a pivotal role in the management of these diseases, leading to better drug dosage, confirmation of the usefulness of the treatment, and early modification of the therapeutic strategy. However, to date, the role of [ 18 F]FDG PET/CT for treatment assessment in large vessel diseases, in particular large vessel vasculitis, is not clearly defined and well-designed prospective studies are needed to confirm its possible role in treatment monitoring and treatment guidance.
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- 2023
13. Procedural recommendations of cardiac PET/ CT imaging: standardization in inflammatory-, infective-, infiltrative-, and innervation- (4Is) related cardiovascular diseases: a joint collaboration of the EACVI and the EANM: summary
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Slart, R, Glaudemans, A, Gheysens, O, Lubberink, M, Kero, T, Dweck, M, Habib, G, Gaemperli, O, Saraste, A, Gimelli, A, Georgoulias, P, Verberne, H, Bucerius, J, Rischpler, C, Hyafil, F, Erba, P, Slart R. H. J. A., Glaudemans A. W. J. M., Gheysens O., Lubberink M., Kero T., Dweck M. R., Habib G., Gaemperli O., Saraste A., Gimelli A., Georgoulias P., Verberne H. J., Bucerius J., Rischpler C., Hyafil F., Erba P. A., Slart, R, Glaudemans, A, Gheysens, O, Lubberink, M, Kero, T, Dweck, M, Habib, G, Gaemperli, O, Saraste, A, Gimelli, A, Georgoulias, P, Verberne, H, Bucerius, J, Rischpler, C, Hyafil, F, Erba, P, Slart R. H. J. A., Glaudemans A. W. J. M., Gheysens O., Lubberink M., Kero T., Dweck M. R., Habib G., Gaemperli O., Saraste A., Gimelli A., Georgoulias P., Verberne H. J., Bucerius J., Rischpler C., Hyafil F., and Erba P. A.
- Abstract
With this summarized document we share the standard for positron emission tomography (PET)/(diagnostic)computed tomography (CT) imaging procedures in cardiovascular diseases that are inflammatory, infective, infiltrative, or associated with dysfunctional innervation (4Is) as recently published in the European Journal of Nuclear Medicine and Molecular Imaging. This standard should be applied in clinical practice and integrated in clinical (multicentre) trials for optimal standardization of the procedurals and interpretations. A major focus is put on procedures using [18F]-2-fluoro-2-deoxyglucose ([18F]FDG), but 4Is PET radiopharmaceuticals beyond [18F]FDG are also described in this summarized document. Whilst these novel tracers are currently mainly applied in early clinical trials, some multicentre trials are underway and we foresee in the near future their use in clinical care and inclusion in the clinical guidelines. Diagnosis and management of 4Is related cardiovascular diseases are generally complex and often require a multidisciplinary approach by a team of experts. The new standards described herein should be applied when using PET/CT and PET/magnetic resonance, within a multimodality imaging framework both in clinical practice and in clinical trials for 4Is cardiovascular indications.
- Published
- 2021
14. Position paper of the EACVI and EANM on artificial intelligence applications in multimodality cardiovascular imaging using SPECT/CT, PET/CT, and cardiac CT
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Slart, R, Williams, M, Juarez-Orozco, L, Rischpler, C, Dweck, M, Glaudemans, A, Gimelli, A, Georgoulias, P, Gheysens, O, Gaemperli, O, Habib, G, Hustinx, R, Cosyns, B, Verberne, H, Hyafil, F, Erba, P, Lubberink, M, Slomka, P, Isgum, I, Visvikis, D, Kolossvary, M, Saraste, A, Slart R. H. J. A., Williams M. C., Juarez-Orozco L. E., Rischpler C., Dweck M. R., Glaudemans A. W. J. M., Gimelli A., Georgoulias P., Gheysens O., Gaemperli O., Habib G., Hustinx R., Cosyns B., Verberne H. J., Hyafil F., Erba P. A., Lubberink M., Slomka P., Isgum I., Visvikis D., Kolossvary M., Saraste A., Slart, R, Williams, M, Juarez-Orozco, L, Rischpler, C, Dweck, M, Glaudemans, A, Gimelli, A, Georgoulias, P, Gheysens, O, Gaemperli, O, Habib, G, Hustinx, R, Cosyns, B, Verberne, H, Hyafil, F, Erba, P, Lubberink, M, Slomka, P, Isgum, I, Visvikis, D, Kolossvary, M, Saraste, A, Slart R. H. J. A., Williams M. C., Juarez-Orozco L. E., Rischpler C., Dweck M. R., Glaudemans A. W. J. M., Gimelli A., Georgoulias P., Gheysens O., Gaemperli O., Habib G., Hustinx R., Cosyns B., Verberne H. J., Hyafil F., Erba P. A., Lubberink M., Slomka P., Isgum I., Visvikis D., Kolossvary M., and Saraste A.
- Abstract
In daily clinical practice, clinicians integrate available data to ascertain the diagnostic and prognostic probability of a disease or clinical outcome for their patients. For patients with suspected or known cardiovascular disease, several anatomical and functional imaging techniques are commonly performed to aid this endeavor, including coronary computed tomography angiography (CCTA) and nuclear cardiology imaging. Continuous improvement in positron emission tomography (PET), single-photon emission computed tomography (SPECT), and CT hardware and software has resulted in improved diagnostic performance and wide implementation of these imaging techniques in daily clinical practice. However, the human ability to interpret, quantify, and integrate these data sets is limited. The identification of novel markers and application of machine learning (ML) algorithms, including deep learning (DL) to cardiovascular imaging techniques will further improve diagnosis and prognostication for patients with cardiovascular diseases. The goal of this position paper of the European Association of Nuclear Medicine (EANM) and the European Association of Cardiovascular Imaging (EACVI) is to provide an overview of the general concepts behind modern machine learning-based artificial intelligence, highlights currently prefered methods, practices, and computational models, and proposes new strategies to support the clinical application of ML in the field of cardiovascular imaging using nuclear cardiology (hybrid) and CT techniques.
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- 2021
15. Procedural recommendations of cardiac PET/CT imaging: standardization in inflammatory-, infective-, infiltrative-, and innervation (4Is)-related cardiovascular diseases: a joint collaboration of the EACVI and the EANM
- Author
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Slart, R, Glaudemans, A, Gheysens, O, Lubberink, M, Kero, T, Dweck, M, Habib, G, Gaemperli, O, Saraste, A, Gimelli, A, Georgoulias, P, Verberne, H, Bucerius, J, Rischpler, C, Hyafil, F, Erba, P, Slart R. H. J. A., Glaudemans A. W. J. M., Gheysens O., Lubberink M., Kero T., Dweck M. R., Habib G., Gaemperli O., Saraste A., Gimelli A., Georgoulias P., Verberne H. J., Bucerius J., Rischpler C., Hyafil F., Erba P. A., Slart, R, Glaudemans, A, Gheysens, O, Lubberink, M, Kero, T, Dweck, M, Habib, G, Gaemperli, O, Saraste, A, Gimelli, A, Georgoulias, P, Verberne, H, Bucerius, J, Rischpler, C, Hyafil, F, Erba, P, Slart R. H. J. A., Glaudemans A. W. J. M., Gheysens O., Lubberink M., Kero T., Dweck M. R., Habib G., Gaemperli O., Saraste A., Gimelli A., Georgoulias P., Verberne H. J., Bucerius J., Rischpler C., Hyafil F., and Erba P. A.
- Abstract
With this document, we provide a standard for PET/(diagnostic) CT imaging procedures in cardiovascular diseases that are inflammatory, infective, infiltrative, or associated with dysfunctional innervation (4Is). This standard should be applied in clinical practice and integrated in clinical (multicenter) trials for optimal procedural standardization. A major focus is put on procedures using [18F]FDG, but 4Is PET radiopharmaceuticals beyond [18F]FDG are also described in this document. Whilst these novel tracers are currently mainly applied in early clinical trials, some multicenter trials are underway and we foresee in the near future their use in clinical care and inclusion in the clinical guidelines. Finally, PET/MR applications in 4Is cardiovascular diseases are also briefly described. Diagnosis and management of 4Is-related cardiovascular diseases are generally complex and often require a multidisciplinary approach by a team of experts. The new standards described herein should be applied when using PET/CT and PET/MR, within a multimodality imaging framework both in clinical practice and in clinical trials for 4Is cardiovascular indications.
- Published
- 2021
16. Impact of COVID-19 on the imaging diagnosis of cardiac disease in Europe
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Williams, M, Shaw, L, Hirschfeld, C, Maurovich-Horvat, P, Norgaard, B, Pontone, G, Jimenez-Heffernan, A, Sinitsyn, V, Sergienko, V, Ansheles, A, Bax, J, Buechel, R, Milan, E, Slart, R, Nicol, E, Bucciarelli-Ducci, C, Pynda, Y, Better, N, Cerci, R, Dorbala, S, Raggi, P, Villines, T, Vitola, J, Malkovskiy, E, Goebel, B, Cohen, Y, Randazzo, M, Pascual, T, Dondi, M, Paez, D, Einstein, A, Nasery, M, Goda, A, Shirka, E, Benlabgaa, R, Bouyoucef, S, Medjahedi, A, Nailli, Q, Agolti, M, Aguero, R, Del Carmen Alak, M, Alberguina, L, Arronada, G, Astesiano, A, Norton, C, Benteo, P, Blanco, J, Bonelli, J, Bustos, J, Cabrejas, R, Cachero, J, Campisi, R, Canderoli, A, Carames, S, Carrascosa, P, Castro, R, Cendoya, O, Cognigni, L, Collaud, C, Cortes, C, Courtis, J, Cragnolino, D, Daicz, M, De La Vega, A, De Maria, S, Del Riego, H, Dettori, F, Deviggiano, A, Dragonetti, L, Embon, M, Enriquez, R, Ensinas, J, Faccio, F, Facello, A, Garofalo, D, Geronazzo, R, Gonza, N, Gutierrez, L, Guzzo, M, Hasbani, V, Huerin, M, Jager, V, Lewkowicz, J, De Munain, M, Lotti, J, Marquez, A, Masoli, O, Mastrovito, E, Mayoraz, M, Melado, G, Mele, A, Merani, M, Meretta, A, Molteni, S, Montecinos, M, Noguera, E, Novoa, C, Sueldo, C, Ascani, S, Pollono, P, Pujol, M, Radzinschi, A, Raimondi, G, Redruello, M, Rodriguez, M, Romero, R, Acuna, A, Rovaletti, F, Miguel, L, Solari, L, Strada, B, Traverso, S, Traverzo, S, Del Huerto Velazquez Espeche, M, Weihmuller, J, Wolcan, J, Zeffiro, S, Sakanyan, M, Beuzeville, S, Boktor, R, Butler, P, Calcott, J, Carr, L, Chan, V, Chao, C, Chong, W, Dobson, M, Downie, D, Dwivedi, G, Elison, B, Engela, J, Francis, R, Gaikwad, A, Basavaraj, A, Goodwin, B, Greenough, R, Hamilton-Craig, C, Hsieh, V, Joshi, S, Lederer, K, Lee, K, Lee, J, Magnussen, J, Mai, N, Mander, G, Murton, F, Nandurkar, D, Neill, J, O'Rourke, E, O'Sullivan, P, Pandos, G, Pathmaraj, K, Pitman, A, Poulter, R, Premaratne, M, Prior, D, Ridley, L, Rutherford, N, Salehi, H, Saunders, C, Scarlett, L, Seneviratne, S, Shetty, D, Shrestha, G, Shulman, J, Solanki, V, Stanton, T, Stuart, M, Stubbs, M, Swainson, I, Taubman, K, Taylor, A, Thomas, P, Unger, S, Upton, A, Vamadevan, S, Van Gaal, W, Verjans, J, Voutnis, D, Wayne, V, Wilson, P, Wong, D, Wong, K, Younger, J, Feuchtner, G, Mirzaei, S, Weiss, K, Maroz-Vadalazhskaya, N, Gheysens, O, Homans, F, Moreno-Reyes, R, Pasquet, A, Roelants, V, Van De Heyning, C, Rios, R, Soldat-Stankovic, V, Stankovic, S, Siqueira, M, Almeida, A, Togni, P, Andrade, J, Andrade, L, Anselmi, C, Araujo, R, Azevedo, G, Bezerra, S, Biancardi, R, Grossman, G, Brandao, S, Pianta, D, Carreira, L, Castro, B, Chang, T, Cunali, F, Cury, R, Dantas, R, De Amorim Fernandes, F, De Lorenzo, A, De MacEdo Filho, R, Erthal, F, Fernandes, F, Fernandes, J, De Souza, T, Alves, W, Ghini, B, Goncalves, L, Gottlieb, I, Hadlich, M, Kameoka, V, Lima, R, Lima, A, Lopes, R, E Silva, R, Magalhaes, T, Silva, F, Mastrocola, L, Medeiros, F, Meneghetti, J, Naue, V, Naves, D, Nolasco, R, Nomura, C, Oliveira, J, Paixao, E, De Carvalho, F, Pinto, I, Possetti, P, Quinta, M, Ramos, R, Rocha, R, Rodrigues, A, Rodrigues, C, Romantini, L, Sanches, A, Santana, S, Da Silva, L, Schvartzman, P, Matushita, C, Senra, T, Shiozaki, A, De Siqueira, M, Siqueira, C, Smanio, P, Soares, C, Soares, J, Bittencourt, M, Spiro, B, Mesquita, C, Torreao, J, Torres, R, Uellendahl, M, Monte, G, Verissimo, O, Cabeda, E, Pedras, F, Waltrick, R, Zapparoli, M, Naseer, H, Garcheva-Tsacheva, M, Kostadinova, I, Theng, Y, Abikhzer, G, Barette, R, Chow, B, Dabreo, D, Friedrich, M, Garg, R, Hafez, M, Johnson, C, Kiess, M, Leipsic, J, Leung, E, Miller, R, Oikonomou, A, Probst, S, Roifman, I, Small, G, Tandon, V, Trivedi, A, White, J, Zukotynski, K, Canessa, J, Munoz, G, Concha, C, Hidalgo, P, Lovera, C, Massardo, T, Vargas, L, Abad, P, Arturo, H, Ayala, S, Benitez, L, Cadena, A, Caicedo, C, Moncayo, A, Gomez, S, Villamil, C, Jaimes, C, Londono, J, Blair, J, Pabon, L, Pineda, M, Rojas, J, Ruiz, D, Escobar, M, Vasquez, A, Vergel, D, Zuluaga, A, Gamboa, I, Castro, G, Gonzalez, U, Baric, A, Batinic, T, Franceschi, M, Hrabak, M, Jukic, M, Medakovic, P, Persic, V, Prpic, M, Punda, A, Batista, J, Lauchy, J, Gutierrez, Y, Menendez, R, Peix, A, Rochela, L, Panagidis, C, Petrou, I, Engelmann, V, Kaminek, M, Kincl, V, Lang, O, Simanek, M, Abdulla, J, Bottcher, M, Christensen, M, Gormsen, L, Hasbak, P, Hess, S, Holdgaard, P, Johansen, A, Kyhl, K, Ovrehus, K, Sand, N, Steffensen, R, Thomassen, A, Zerahn, B, Perez, A, Velez, G, Velez, M, Aziz, I, Abougabal, M, Ahmed, T, Allam, A, Asfour, A, Hassan, M, Hassan, A, Ibrahim, A, Kaffas, S, Kandeel, A, Ali, M, Mansy, A, Maurice, H, Nabil, S, Shaaban, M, Flores, A, Poksi, A, Knuuti, J, Kokkonen, V, Larikka, M, Uusitalo, V, Bailly, M, Burg, S, Deux, J, Habouzit, V, Hyafil, F, Lairez, O, Proffit, F, Regaieg, H, Sarda-Mantel, L, Tacher, V, Schneider, R, Ayetey, H, Angelidis, G, Archontaki, A, Chatziioannou, S, Datseris, I, Fragkaki, C, Georgoulias, P, Koukouraki, S, Koutelou, M, Kyrozi, E, Repasos, E, Stavrou, P, Valsamaki, P, Gonzalez, C, Gutierrez, G, Maldonado, A, Buga, K, Garai, I, Schmidt, E, Szilveszter, B, Varady, E, Banthia, N, Bhagat, J, Bhargava, R, Bhat, V, Bhatia, M, Choudhury, P, Chowdekar, V, Irodi, A, Jain, S, Joseph, E, Kumar, S, Mahapatra, G, Mitra, D, Mittal, B, Ozair, A, Patel, C, Patel, T, Patel, R, Patel, S, Saxena, S, Sengupta, S, Singh, S, Singh, B, Sood, A, Verma, A, Affandi, E, Alam, P, Edison, E, Gunawan, G, Hapkido, H, Hidayat, B, Huda, A, Mukti, A, Prawiro, D, Soeriadi, E, Syawaluddin, H, Albadr, A, Assadi, M, Emami, F, Houshmand, G, Maleki, M, Rostami, M, Zakavi, S, Zaid, E, Agranovich, S, Arnson, Y, Bar-Shalom, R, Frenkel, A, Knafo, G, Lugassi, R, Moalem, I, Mor, M, Muskal, N, Ranser, S, Shalev, A, Albano, D, Alongi, P, Arnone, G, Bagatin, E, Baldari, S, Bauckneht, M, Bertelli, P, Bianco, F, Bonfiglioli, R, Boni, R, Bruno, A, Bruno, I, Busnardo, E, Califaretti, E, Camoni, L, Carnevale, A, Casoni, R, Cavallo, A, Cavenaghi, G, Chierichetti, F, Chiocchi, M, Cittanti, C, Colletta, M, Conti, U, Cossu, A, Cuocolo, A, Cuzzocrea, M, De Rimini, M, De Vincentis, G, Del Giudice, E, Del Torto, A, Della Tommasina, V, Durmo, R, Erba, P, Evangelista, L, Faletti, R, Faragasso, E, Farsad, M, Ferro, P, Florimonte, L, Frantellizzi, V, Fringuelli, F, Gatti, M, Gaudiano, A, Gimelli, A, Giubbini, R, Giuffrida, F, Ialuna, S, Laudicella, R, Leccisotti, L, Leva, L, Liga, R, Liguori, C, Longo, G, Maffione, M, Mancini, M, Marcassa, C, Nardi, B, Pacella, S, Pepe, G, Pulizzi, S, Quartuccio, N, Rampin, L, Ricci, F, Rossini, P, Rubini, G, Russo, V, Sacchetti, G, Sambuceti, G, Scarano, M, Sciagra, R, Sperandio, M, Stefanelli, A, Ventroni, G, Zoboli, S, Baugh, D, Chambers, D, Madu, E, Nunura, F, Asano, H, Chimura, C, Fujimoto, S, Fujisue, K, Fukunaga, T, Fukushima, Y, Fukuyama, K, Hashimoto, J, Ichikawa, Y, Iguchi, N, Imai, M, Inaki, A, Ishimura, H, Isobe, S, Kadokami, T, Kato, T, Kudo, T, Kumita, S, Maruno, H, Mataki, H, Miyagawa, M, Morimoto, R, Moroi, M, Nagamachi, S, Nakajima, K, Nakata, T, Nakazato, R, Nanasato, M, Naya, M, Norikane, T, Ohta, Y, Okayama, S, Okizaki, A, Otomi, Y, Otsuka, H, Saito, M, Sakata, S, Sarai, M, Sato, D, Shiraishi, S, Suwa, Y, Takanami, K, Takehana, K, Taki, J, Tamaki, N, Taniguchi, Y, Teragawa, H, Tomizawa, N, Tsujita, K, Umeji, K, Wakabayashi, Y, Yamada, S, Yamazaki, S, Yoneyama, T, Rawashdeh, M, Batyrkhanov, D, Dautov, T, Makhdomi, K, Ombati, K, Alkandari, F, Garashi, M, Coie, T, Rajvong, S, Kalinin, A, Kalnina, M, Haidar, M, Komiagiene, R, Kviecinskiene, G, Mataciunas, M, Vajauskas, D, Picard, C, Karim, N, Reichmuth, L, Samuel, A, Allarakha, M, Naojee, A, Alexanderson-Rosas, E, Barragan, E, Becerril, A, Gonzalez-Montecinos, Cabada, M, Rodriguez, D, Carvajal-Juarez, I, Cortes, V, Cortes, F, De La Pena, E, Gama-Moreno, M, Gonzalez, L, Ramirez, N, Jimenez-Santos, M, Matos, L, Monroy, E, Morelos, M, Ornelas, M, Ramirez, J, Preciado-Anaya, A, Preciado-Gutierrez, O, Barragan, 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J., Kaplan M., Khushica P., Lakhi H., Louw L., Malan N., Milos K., Modiselle M., More S., Naidoo M., Scholtz L., Vangu M., Aguade-Bruix S., Blanco I., Cabrera A., Camarero A., Casans-Tormo I., Cuellar-Calabria H., Flotats A., Canamero M. E. F., Garcia M. E., Leta R., Diaz J. L., Lumbreras L., Marquez-Cabeza J. J., Martin F., De Alegria A. M., Medina F., Canal M. P., Peiro V., Pubul-Nunez V., Madrid J. I. R., Rey C. R., Perez R. R., Ruiz J., Hernandez G. S., Sevilla A., Zeidan N., Nanayakkara D., Udugama C., Simonsson M., Alkadhi H., Buechel R. R., Burger P., Ceriani L., De Boeck B., Grani C., De Saint Lager Lucas A. J., Kamani C. H., Kawel-Boehm N., Manka R., Prior J. O., Rominger A., Vallee J. -P., Khiewvan B., Premprabha T., Thientunyakit T., Sellem A., Kir K. M., Sayman H., Sebikali M. J., Muyinda Z., Kmetyuk Y., Korol P., Mykhalchenko O., Pliatsek V., Satyr M., Albalooshi B., Hassan M. I. A., Anderson J., Bedi P., Biggans T., Bularga A., Bull R., Burgul R., Carpenter J. -P., Coles D., Cusack D., Deshpande A., Dougan J., Fairbairn T., Farrugia A., Gopalan D., Gummow A., Ramkumar P. G., Hamilton M., Harbinson M., Hartley T., Hudson B., Joshi N., Kay M., Kelion A., Khokhar A., Kitt J., Low C., Mak S. M., Marousa N., Martin J., McAlindon E., Menezes L., Morgan-Hughes G., Moss A., Murray A., Patel D., Peebles C., Pugliese F., Rodrigues J. C. L., Rofe C., Sabharwal N., Schofield R., Semple T., Sharma N., Strouhal P., Subedi D., Topping W., Tweed K., Weir-Mccall J., Abbara S., Abbasi T., Abbott B., Abohashem S., Abramson S., Al-Abboud T., Al-Mallah M., Almousalli O., Ananthasubramaniam K., Kumar M. A., Askew J., Attanasio L., Balmer-Swain M., Bayer R. R., Bernheim A., Bhatti S., Bieging E., Blankstein R., Bloom S., Blue S., Bluemke D., Borges A., Branch K., Bravo P., Brothers J., Budoff M., Bullock-Palmer R., Burandt A., Burke F. W., Bush K., Candela C., Capasso E., Cavalcante J., Chang D., Chatterjee S., Chatzizisis Y., Cheezum M., Chen T., Chen J., Chen M., Choi A., Clarcq J., Cordero A., Crim M., Danciu S., Decter B., Dhruva N., Doherty N., Doukky R., Dunbar A., Duvall W., Edwards R., Esquitin K., Farah H., Fentanes E., Ferencik M., Fisher D., Fitzpatrick D., Foster C., Fuisz T., Gannon M., Gastner L., Gerson M., Ghoshhajra B., Goldberg A., Goldner B., Gonzalez J., Gore R., Gracia-Lopez S., Hage F., Haider A., Haider S., Hamirani Y., Hassen K., Hatfield M., Hawkins C., Hawthorne K., Heath N., Hendel R., Hernandez P., Hill G., Horgan S., Huffman J., Hurwitz L., Iskandrian A., Janardhanan R., Jellis C., Jerome S., Kalra D., Kaviratne S., Kay F., Kelly F., Khalique O., Kinkhabwala M., Iii G. K., Kircher J., Kirkbride R., Kontos M., Kottam A., Krepp J., Layer J., Lee S. H., Leppo J., Lesser J., Leung S., Lewin H., Litmanovich D., Liu Y., Lopez-Mattei J., Magurany K., Markowitz J., Marn A., Matis S. E., McKenna M., McRae T., Mendoza F., Merhige M., Min D., Moffitt C., Moncher K., Moore W., Morayati S., Morris M., Mossa-Basha M., Mrsic Z., Murthy V., Nagpal P., Napier K., Narula J., Nelson K., Nijjar P., Osman M., Parwani P., Passen E., Patel A., Patil P., Paul R., Phillips L., Polsani V., Poludasu R., Pomerantz B., Porter T., Prentice R., Pursnani A., Rabbat M., Ramamurti S., Rich F., Luna H. R., Robinson A., Robles K., Rodriguez C., Rorie M., Rumberger J., Russell R., Sabra P., Sadler D., Schemmer M., Schoepf U. J., Shah S., Shah N., Shanbhag S., Sharma G., Shayani S., Shirani J., Shivaram P., Sigman S., Simon M., Slim A., Smith D., Smith A., Soman P., Srichai-Parsia M. B., Streeter J., Albert T., Tawakol A., Thomas D., Thompson R., Torbet T., Trinidad D., Ullery S., Unzek S., Uretsky S., Vallurupalli S., Verma V., Waller A., Wang E., Ward P., Weissman G., Wesbey G., White K., Winchester D., Wolinsky D., Yost S., Zgaljardic M., Alonso O., Beretta M., Ferrando R., Kapitan M., Mut F., Djuraev O., Rozikhodjaeva G., Ngoc H. L., Mai S. H., and Nguyen X. C.
- Abstract
Objectives We aimed to explore the impact of the COVID-19 pandemic on cardiac diagnostic testing and practice and to assess its impact in different regions in Europe. Methods The online survey organised by the International Atomic Energy Agency Division of Human Health collected information on changes in cardiac imaging procedural volumes between March 2019 and March/April 2020. Data were collected from 909 centres in 108 countries. Results Centres in Northern and Southern Europe were more likely to cancel all outpatient activities compared with Western and Eastern Europe. There was a greater reduction in total procedure volumes in Europe compared with the rest of the world in March 2020 (45% vs 41%, p=0.003), with a more marked reduction in Southern Europe (58%), but by April 2020 this was similar in Europe and the rest of the world (69% vs 63%, p=0.261). Regional variations were apparent between imaging modalities, but the largest reductions were in Southern Europe for nearly all modalities. In March 2020, location in Southern Europe was the only independent predictor of the reduction in procedure volume. However, in April 2020, lower gross domestic product and higher COVID-19 deaths were the only independent predictors. Conclusion The first wave of the COVID-19 pandemic had a significant impact on care of patients with cardiac disease, with substantial regional variations in Europe. This has potential long-term implications for patients and plans are required to enable the diagnosis of non-COVID- 19 conditions during the ongoing pandemic.
- Published
- 2021
17. Correction to: In-depth characterization of the tumor microenvironment in central nervous system lymphoma reveals implications for immune-checkpoint therapy (Cancer Immunology, Immunotherapy, (2020), 69, 9, (1751-1766), 10.1007/s00262-020-02575-y)
- Author
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Marcelis L., Marcelis, L, Antoranz, A, Delsupehe, A, Biesemans, P, Ferreiro, J, Debackere, K, Vandenberghe, P, Verhoef, G, Clement, P, De Vleeschouwer, S, Gheysens, O, Cattoretti, G, Bosisio, F, Sagaert, X, Dierickx, D, Tousseyn, T, Marcelis L., Antoranz A., Delsupehe A. -M., Biesemans P., Ferreiro J. F., Debackere K., Vandenberghe P., Verhoef G., Clement P., De Vleeschouwer S., Gheysens O., Cattoretti G., Bosisio F. M., Sagaert X., Dierickx D., Tousseyn T., Marcelis L., Marcelis, L, Antoranz, A, Delsupehe, A, Biesemans, P, Ferreiro, J, Debackere, K, Vandenberghe, P, Verhoef, G, Clement, P, De Vleeschouwer, S, Gheysens, O, Cattoretti, G, Bosisio, F, Sagaert, X, Dierickx, D, Tousseyn, T, Marcelis L., Antoranz A., Delsupehe A. -M., Biesemans P., Ferreiro J. F., Debackere K., Vandenberghe P., Verhoef G., Clement P., De Vleeschouwer S., Gheysens O., Cattoretti G., Bosisio F. M., Sagaert X., Dierickx D., and Tousseyn T.
- Abstract
The original version of this article unfortunately contained a mistake. Paul Clement and Steven De Vleeschouwer were not listed among the authors.
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- 2021
18. Pirfenidone: A Potential New Therapy for Restrictive Allograft Syndrome?
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Vos, R., Verleden, S.E., Ruttens, D., Vandermeulen, E., Yserbyt, J., Dupont, L.J., Van Raemdonck, D.E., De Raedt, N., Gheysens, O., De Jong, P.A., Verleden, G.M., and Vanaudenaerde, B.M.
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- 2013
- Full Text
- View/download PDF
19. Joint EANM/SNMMI/ANZSNM practice guidelines/procedure standards on recommended use of [18F]FDG PET/CT imaging during immunomodulatory treatments in patients with solid tumors version 1.0.
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Lopci, E, Hicks, RJ, Dimitrakopoulou-Strauss, A, Dercle, L, Iravani, A, Seban, RD, Sachpekidis, C, Humbert, O, Gheysens, O, Glaudemans, AWJM, Weber, W, Wahl, RL, Scott, AM, Pandit-Taskar, N, Aide, N, Lopci, E, Hicks, RJ, Dimitrakopoulou-Strauss, A, Dercle, L, Iravani, A, Seban, RD, Sachpekidis, C, Humbert, O, Gheysens, O, Glaudemans, AWJM, Weber, W, Wahl, RL, Scott, AM, Pandit-Taskar, N, and Aide, N
- Abstract
PURPOSE: The goal of this guideline/procedure standard is to assist nuclear medicine physicians, other nuclear medicine professionals, oncologists or other medical specialists for recommended use of [18F]FDG PET/CT in oncological patients undergoing immunotherapy, with special focus on response assessment in solid tumors. METHODS: In a cooperative effort between the EANM, the SNMMI and the ANZSNM, clinical indications, recommended imaging procedures and reporting standards have been agreed upon and summarized in this joint guideline/procedure standard. CONCLUSIONS: The field of immuno-oncology is rapidly evolving, and this guideline/procedure standard should not be seen as definitive, but rather as a guidance document standardizing the use and interpretation of [18F]FDG PET/CT during immunotherapy. Local variations to this guideline should be taken into consideration. PREAMBLE: The European Association of Nuclear Medicine (EANM) is a professional non-profit medical association founded in 1985 to facilitate worldwide communication among individuals pursuing clinical and academic excellence in nuclear medicine. The Society of Nuclear Medicine and Molecular Imaging (SNMMI) is an international scientific and professional organization founded in 1954 to promote science, technology and practical application of nuclear medicine. The Australian and New Zealand Society of Nuclear Medicine (ANZSNM), founded in 1969, represents the major professional society fostering the technical and professional development of nuclear medicine practice across Australia and New Zealand. It promotes excellence in the nuclear medicine profession through education, research and a commitment to the highest professional standards. EANM, SNMMI and ANZSNM members are physicians, technologists, physicists and scientists specialized in the research and clinical practice of nuclear medicine. All three societies will periodically put forth new standards/guidelines for nuclear medicine practice to help
- Published
- 2022
20. Joint EANM/SNMMI/ANZSNM practice guidelines/procedure standards on recommended use of [F]FDG PET/CT imaging during immunomodulatory treatments in patients with solid tumors version 1.0.
- Author
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UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Centre du cancer, UCL - (SLuc) Service de médecine nucléaire, Lopci, E, Hicks, R J, Dimitrakopoulou-Strauss, A, Dercle, L, Iravani, A, Seban, R D, Sachpekidis, C, Humbert, O, Gheysens, O, Glaudemans, A W J M, Weber, W, Wahl, R L, Scott, A M, Pandit-Taskar, N, Aide, N, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Centre du cancer, UCL - (SLuc) Service de médecine nucléaire, Lopci, E, Hicks, R J, Dimitrakopoulou-Strauss, A, Dercle, L, Iravani, A, Seban, R D, Sachpekidis, C, Humbert, O, Gheysens, O, Glaudemans, A W J M, Weber, W, Wahl, R L, Scott, A M, Pandit-Taskar, N, and Aide, N
- Abstract
The goal of this guideline/procedure standard is to assist nuclear medicine physicians, other nuclear medicine professionals, oncologists or other medical specialists for recommended use of [F]FDG PET/CT in oncological patients undergoing immunotherapy, with special focus on response assessment in solid tumors. In a cooperative effort between the EANM, the SNMMI and the ANZSNM, clinical indications, recommended imaging procedures and reporting standards have been agreed upon and summarized in this joint guideline/procedure standard. The field of immuno-oncology is rapidly evolving, and this guideline/procedure standard should not be seen as definitive, but rather as a guidance document standardizing the use and interpretation of [F]FDG PET/CT during immunotherapy. Local variations to this guideline should be taken into consideration. The European Association of Nuclear Medicine (EANM) is a professional non-profit medical association founded in 1985 to facilitate worldwide communication among individuals pursuing clinical and academic excellence in nuclear medicine. The Society of Nuclear Medicine and Molecular Imaging (SNMMI) is an international scientific and professional organization founded in 1954 to promote science, technology and practical application of nuclear medicine. The Australian and New Zealand Society of Nuclear Medicine (ANZSNM), founded in 1969, represents the major professional society fostering the technical and professional development of nuclear medicine practice across Australia and New Zealand. It promotes excellence in the nuclear medicine profession through education, research and a commitment to the highest professional standards. EANM, SNMMI and ANZSNM members are physicians, technologists, physicists and scientists specialized in the research and clinical practice of nuclear medicine. All three societies will periodically put forth new standards/guidelines for nuclear medicine practice to help advance the science of nuclear medicine and i
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- 2022
21. Perspectives on joint EANM/SNMMI/ANZSNM practice guidelines/procedure standards for [F-18]FDG PET/CT imaging during immunomodulatory treatments in patients with solid tumors
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Lopci, E, Aide, N, Dimitrakopoulou-Strauss, A, Dercle, L, Iravani, A, Seban, RD, Sachpekidis, C, Humbert, O, Gheysens, O, Glaudemans, AWJM, Weber, WA, Van den Abbeele, AD, Wahl, RL, Scott, AM, Pandit-Taskar, N, Hicks, RJ, Lopci, E, Aide, N, Dimitrakopoulou-Strauss, A, Dercle, L, Iravani, A, Seban, RD, Sachpekidis, C, Humbert, O, Gheysens, O, Glaudemans, AWJM, Weber, WA, Van den Abbeele, AD, Wahl, RL, Scott, AM, Pandit-Taskar, N, and Hicks, RJ
- Abstract
Response assessment in the context of immunomodulatory treatments represents a major challenge for the medical imaging community and requires a multidisciplinary approach with involvement of oncologists, radiologists, and nuclear medicine specialists. There is evolving evidence that [18F]FDG PET/CT is a useful diagnostic modality for this purpose. The clinical indications for, and the principal aspects of its standardization in this context have been detailed in the recently published "Joint EANM/SNMMI/ANZSNM practice guidelines/procedure standards on recommended use of [18F]FDG PET/CT imaging during immunomodulatory treatments in patients with solid tumors version 1.0". These recommendations arose from a fruitful collaboration between international nuclear medicine societies and experts in cancer treatment. In this perspective, the key elements of the initiative are reported, summarizing the core aspects of the guidelines for radiologists and nuclear medicine physicians. Beyond the previous guidelines, this perspective adds further commentary on how this technology can advance development of novel therapeutic approaches and guide management of individual patients.
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- 2022
22. Joint EANM/SNMMI/ANZSNM practice guidelines/procedure standards on recommended use of [F]FDG PET/CT imaging during immunomodulatory treatments in patients with solid tumors version 1.0
- Author
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Lopci, E, Hicks, R J, Dimitrakopoulou-Strauss, A, Dercle, L, Iravani, A, Seban, R D, Sachpekidis, C, Humbert, O, Gheysens, O, Glaudemans, A W J M, Weber, W, Wahl, R L, Scott, A M, Pandit-Taskar, N, Aide, N, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Centre du cancer, and UCL - (SLuc) Service de médecine nucléaire
- Subjects
Positron emission tomography ,PET/CT ,Australia ,treatment response ,Molecular Imaging ,Fluorodeoxyglucose F18 ,Neoplasms ,Positron Emission Tomography Computed Tomography ,Humans ,immunotherapy ,Nuclear Medicine ,[18F]FDG ,Societies ,guideline ,malignant tumors - Abstract
The goal of this guideline/procedure standard is to assist nuclear medicine physicians, other nuclear medicine professionals, oncologists or other medical specialists for recommended use of [F]FDG PET/CT in oncological patients undergoing immunotherapy, with special focus on response assessment in solid tumors. In a cooperative effort between the EANM, the SNMMI and the ANZSNM, clinical indications, recommended imaging procedures and reporting standards have been agreed upon and summarized in this joint guideline/procedure standard. The field of immuno-oncology is rapidly evolving, and this guideline/procedure standard should not be seen as definitive, but rather as a guidance document standardizing the use and interpretation of [F]FDG PET/CT during immunotherapy. Local variations to this guideline should be taken into consideration. The European Association of Nuclear Medicine (EANM) is a professional non-profit medical association founded in 1985 to facilitate worldwide communication among individuals pursuing clinical and academic excellence in nuclear medicine. The Society of Nuclear Medicine and Molecular Imaging (SNMMI) is an international scientific and professional organization founded in 1954 to promote science, technology and practical application of nuclear medicine. The Australian and New Zealand Society of Nuclear Medicine (ANZSNM), founded in 1969, represents the major professional society fostering the technical and professional development of nuclear medicine practice across Australia and New Zealand. It promotes excellence in the nuclear medicine profession through education, research and a commitment to the highest professional standards. EANM, SNMMI and ANZSNM members are physicians, technologists, physicists and scientists specialized in the research and clinical practice of nuclear medicine. All three societies will periodically put forth new standards/guidelines for nuclear medicine practice to help advance the science of nuclear medicine and improve service to patients. Existing standards/guidelines will be reviewed for revision or renewal, as appropriate, on their fifth anniversary or sooner, if indicated. Each standard/guideline, representing a policy statement by the EANM/SNMMI/ANZSNM, has undergone a thorough consensus process, entailing extensive review. These societies recognize that the safe and effective use of diagnostic nuclear medicine imaging requires particular training and skills, as described in each document. These standards/guidelines are educational tools designed to assist practitioners in providing appropriate and effective nuclear medicine care for patients. These guidelines are consensus documents based on current knowledge. They are not intended to be inflexible rules or requirements of practice, nor should they be used to establish a legal standard of care. For these reasons and those set forth below, the EANM, SNMMI and ANZSNM caution against the use of these standards/guidelines in litigation in which the clinical decisions of a practitioner are called into question. The ultimate judgment regarding the propriety of any specific procedure or course of action must be made by medical professionals considering the unique circumstances of each case. Thus, there is no implication that an action differing from what is laid out in the guidelines/procedure standards, standing alone, is below standard of care. To the contrary, a conscientious practitioner may responsibly adopt a course of action different from that set forth in the standards/guidelines when, in the reasonable judgment of the practitioner, such course of action is indicated by the condition of the patient, limitations of available resources or advances in knowledge or technology subsequent to publication of the guidelines/procedure standards. The practice of medicine involves not only the science, but also the art of dealing with the prevention, diagnosis, alleviation and treatment of disease. The variety and complexity of human conditions make it impossible for general guidelines to consistently allow for an accurate diagnosis to be reached or a particular treatment response to be predicted. Therefore, it should be recognized that adherence to these standards/ guidelines will not ensure a successful outcome. All that should be expected is that practitioners follow a reasonable course of action, based on their level of training, current knowledge, clinical practice guidelines, available resources and the needs/context of the patient being treated. The sole purpose of these guidelines is to assist practitioners in achieving this objective. The present guideline/procedure standard was developed collaboratively by the EANM, the SNMMI and the ANZSNM, with the support of international experts in the field. They summarize also the views of the Oncology and Theranostics and the Inflammation and Infection Committees of the EANM, as well as the procedure standards committee of the SNMMI, and reflect recommendations for which the EANM and SNMMI cannot be held responsible. The recommendations should be taken into the context of good practice of nuclear medicine and do not substitute for national and international legal or regulatory provisions.
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- 2022
23. Noninvasive Molecular Imaging of Small Living Subjects Using Raman Spectroscopy
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Keren, S., Zavaleta, C., Cheng, Z., de la Zerda, A., Gheysens, O., and Gambhir, S. S.
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- 2008
- Full Text
- View/download PDF
24. Impact of COVID-19 on the imaging diagnosis of cardiac disease in Europe
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Williams M. C., Shaw L., Hirschfeld C. B., Maurovich-Horvat P., Norgaard B. L., Pontone G., Jimenez-Heffernan A., Sinitsyn V., Sergienko V., Ansheles A., Bax J. J., Buechel R., Milan E., Slart R. H. J. A., Nicol E., Bucciarelli-Ducci C., Pynda Y., Better N., Cerci R., Dorbala S., Raggi P., Villines T. C., Vitola J., Malkovskiy E., Goebel B., Cohen Y., Randazzo M., Pascual T. N. B., Dondi M., Paez D., Einstein A. J., Nasery M. N., Goda A., Shirka E., Benlabgaa R., Bouyoucef S., Medjahedi A., Nailli Q., Agolti M., Aguero R. N., Del Carmen Alak M., Alberguina L. G., Arronada G., Astesiano A., Norton C. B., Benteo P., Blanco J., Bonelli J. M., Bustos J. J., Cabrejas R., Cachero J., Campisi R., Canderoli A., Carames S., Carrascosa P., Castro R., Cendoya O., Cognigni L. M., Collaud C., Cortes C., Courtis J., Cragnolino D., Daicz M., De La Vega A., De Maria S. T., Del Riego H., Dettori F., Deviggiano A., Dragonetti L., Embon M., Enriquez R. E., Ensinas J., Faccio F., Facello A., Garofalo D., Geronazzo R., Gonza N., Gutierrez L., Guzzo M. A., Hasbani V., Huerin M., Jager V., Lewkowicz J. M., De Munain M. N. A. L., Lotti J. M., Marquez A., Masoli O., Masoli O. H., Mastrovito E., Mayoraz M., Melado G. E., Mele A., Merani M. F., Meretta A. H., Molteni S., Montecinos M., Noguera E., Novoa C., Sueldo C. P., Ascani S. P., Pollono P., Pujol M. P., Radzinschi A., Raimondi G., Redruello M., Rodriguez M., Romero R. L., Acuna A. R., Rovaletti F., Miguel L. S., Solari L., Strada B., Traverso S., Traverzo S. S., Del Huerto Velazquez Espeche M., Weihmuller J. S., Wolcan J., Zeffiro S., Sakanyan M., Beuzeville S., Boktor R., Butler P., Calcott J., Carr L., Chan V., Chao C., Chong W., Dobson M., Downie D., Dwivedi G., Elison B., Engela J., Francis R., Gaikwad A., Basavaraj A. G., Goodwin B., Greenough R., Hamilton-Craig C., Hsieh V., Joshi S., Lederer K., Lee K., Lee J., Magnussen J., Mai N., Mander G., Murton F., Nandurkar D., Neill J., O'Rourke E., O'Sullivan P., Pandos G., Pathmaraj K., Pitman A., Poulter R., Premaratne M., Prior D., Ridley L., Rutherford N., Salehi H., Saunders C., Scarlett L., Seneviratne S., Shetty D., Shrestha G., Shulman J., Solanki V., Stanton T., Stuart M., Stubbs M., Swainson I., Taubman K., Taylor A., Thomas P., Unger S., Upton A., Vamadevan S., Van Gaal W., Verjans J., Voutnis D., Wayne V., Wilson P., Wong D., Wong K., Younger J., Feuchtner G., Mirzaei S., Weiss K., Maroz-Vadalazhskaya N., Gheysens O., Homans F., Moreno-Reyes R., Pasquet A., Roelants V., Van De Heyning C. M., Rios R. A., Soldat-Stankovic V., Stankovic S., Siqueira M. H. A., Almeida A., Togni P. H. A., Andrade J. H., Andrade L., Anselmi C., Araujo R., Azevedo G., Bezerra S., Biancardi R., Grossman G. B., Brandao S., Pianta D. B., Carreira L., Castro B., Chang T., Cunali F., Cury R., Dantas R., De Amorim Fernandes F., De Lorenzo A., De MacEdo Filho R., Erthal F., Fernandes F., Fernandes J., De Souza T. F., Alves W. F., Ghini B., Goncalves L., Gottlieb I., Hadlich M., Kameoka V., Lima R., Lima A., Lopes R. W., E Silva R. M., Magalhaes T., Silva F. M., Mastrocola L. E., Medeiros F., Meneghetti J. C., Naue V., Naves D., Nolasco R., Nomura C., Oliveira J. B., Paixao E., De Carvalho F. P., Pinto I., Possetti P., Quinta M., Ramos R. R. N., Rocha R., Rodrigues A., Rodrigues C., Romantini L., Sanches A., Santana S., Da Silva L. S., Schvartzman P., Matushita C. S., Senra T., Shiozaki A., De Siqueira M. E. M., Siqueira C., Smanio P., Soares C. E., Soares J., Bittencourt M. S., Spiro B., Mesquita C. T., Torreao J., Torres R., Uellendahl M., Monte G. U., Verissimo O., Cabeda E. V., Pedras F. V., Waltrick R., Zapparoli M., Naseer H., Garcheva-Tsacheva M., Kostadinova I., Theng Y., Abikhzer G., Barette R., Chow B., Dabreo D., Friedrich M., Garg R., Hafez M. N., Johnson C., Kiess M., Leipsic J., Leung E., Miller R., Oikonomou A., Probst S., Roifman I., Small G., Tandon V., Trivedi A., White J., Zukotynski K., Canessa J., Munoz G. C., Concha C., Hidalgo P., Lovera C., Massardo T., Vargas L. S., Abad P., Arturo H., Ayala S., Benitez L., Cadena A., Caicedo C., Moncayo A. C., Gomez S., Villamil C. T. G., Jaimes C., Londono J., Blair J. L. L., Pabon L., Pineda M., Rojas J. C., Ruiz D., Escobar M. V., Vasquez A., Vergel D., Zuluaga A., Gamboa I. B., Castro G., Gonzalez U., Baric A., Batinic T., Franceschi M., Hrabak M., Jukic M., Medakovic P., Persic V., Prpic M., Punda A., Batista J. F., Lauchy J. M. G., Gutierrez Y. M., Menendez R., Peix A., Rochela L., Panagidis C., Petrou I., Engelmann V., Kaminek M., Kincl V., Lang O., Simanek M., Abdulla J., Bottcher M., Christensen M., Gormsen L. C., Hasbak P., Hess S., Holdgaard P., Johansen A., Kyhl K., Ovrehus K. A., Sand N. P. R., Steffensen R., Thomassen A., Zerahn B., Perez A., Velez G. A. E., Velez M. S., Aziz I. S. A., Abougabal M., Ahmed T., Allam A., Asfour A., Hassan M., Hassan A., Ibrahim A., Kaffas S., Kandeel A., Ali M. M., Mansy A., Maurice H., Nabil S., Shaaban M., Flores A. C., Poksi A., Knuuti J., Kokkonen V., Larikka M., Uusitalo V., Bailly M., Burg S., Deux J. -F., Habouzit V., Hyafil F., Lairez O., Proffit F., Regaieg H., Sarda-Mantel L., Tacher V., Schneider R. P., Ayetey H., Angelidis G., Archontaki A., Chatziioannou S., Datseris I., Fragkaki C., Georgoulias P., Koukouraki S., Koutelou M., Kyrozi E., Repasos E., Stavrou P., Valsamaki P., Gonzalez C., Gutierrez G., Maldonado A., Buga K., Garai I., Schmidt E., Szilveszter B., Varady E., Banthia N., Bhagat J. K., Bhargava R., Bhat V., Bhatia M., Choudhury P., Chowdekar V. S., Irodi A., Jain S., Joseph E., Kumar S., Mahapatra G., Mitra D., Mittal B. R., Ozair A., Patel C., Patel T., Patel R., Patel S., Saxena S., Sengupta S., Singh S., Singh B., Sood A., Verma A., Affandi E., Alam P. S., Edison E., Gunawan G., Hapkido H., Hidayat B., Huda A., Mukti A. P., Prawiro D., Soeriadi E. A., Syawaluddin H., Albadr A., Assadi M., Emami F., Houshmand G., Maleki M., Rostami M. T., Zakavi S. R., Zaid E. A., Agranovich S., Arnson Y., Bar-Shalom R., Frenkel A., Knafo G., Lugassi R., Moalem I. S. M., Mor M., Muskal N., Ranser S., Shalev A., Albano D., Alongi P., Arnone G., Bagatin E., Baldari S., Bauckneht M., Bertelli P., Bianco F., Bonfiglioli R., Boni R., Bruno A., Bruno I., Busnardo E., Califaretti E., Camoni L., Carnevale A., Casoni R., Cavallo A. U., Cavenaghi G., Chierichetti F., Chiocchi M., Cittanti C., Colletta M., Conti U., Cossu A., Cuocolo A., Cuzzocrea M., De Rimini M. L., De Vincentis G., Del Giudice E., Del Torto A., Della Tommasina V., Durmo R., Erba P. A., Evangelista L., Faletti R., Faragasso E., Farsad M., Ferro P., Florimonte L., Frantellizzi V., Fringuelli F. M., Gatti M., Gaudiano A., Gimelli A., Giubbini R., Giuffrida F., Ialuna S., Laudicella R., Leccisotti L., Leva L., Liga R., Liguori C., Longo G., Maffione M., Mancini M. E., Marcassa C., Nardi B., Pacella S., Pepe G., Pulizzi S., Quartuccio N., Rampin L., Ricci F., Rossini P., Rubini G., Russo V., Sacchetti G. M., Sambuceti G., Scarano M., Sciagra R., Sperandio M., Stefanelli A., Ventroni G., Zoboli S., Baugh D., Chambers D., Madu E., Nunura F., Asano H., Chimura C. M., Fujimoto S., Fujisue K., Fukunaga T., Fukushima Y., Fukuyama K., Hashimoto J., Ichikawa Y., Iguchi N., Imai M., Inaki A., Ishimura H., Isobe S., Kadokami T., Kato T., Kudo T., Kumita S., Maruno H., Mataki H., Miyagawa M., Morimoto R., Moroi M., Nagamachi S., Nakajima K., Nakata T., Nakazato R., Nanasato M., Naya M., Norikane T., Ohta Y., Okayama S., Okizaki A., Otomi Y., Otsuka H., Saito M., Sakata S. Y., Sarai M., Sato D., Shiraishi S., Suwa Y., Takanami K., Takehana K., Taki J., Tamaki N., Taniguchi Y., Teragawa H., Tomizawa N., Tsujita K., Umeji K., Wakabayashi Y., Yamada S., Yamazaki S., Yoneyama T., Rawashdeh M., Batyrkhanov D., Dautov T., Makhdomi K., Ombati K., Alkandari F., Garashi M., Coie T. L., Rajvong S., Kalinin A., Kalnina M., Haidar M., Komiagiene R., Kviecinskiene G., Mataciunas M., Vajauskas D., Picard C., Karim N. K. A., Reichmuth L., Samuel A., Allarakha M. A., Naojee A. S., Alexanderson-Rosas E., Barragan E., Becerril A., Gonzalez-Montecinos, Cabada M., Rodriguez D. C., Carvajal-Juarez I., Cortes V., Cortes F., De La Pena E., Gama-Moreno M., Gonzalez L., Ramirez N. G., Jimenez-Santos M., Matos L., Monroy E., Morelos M., Ornelas M., Ramirez J. A. O., Preciado-Anaya A., Preciado-Gutierrez O. U., Barragan A. P., Uvera S. G. R., Sandoval S., Tomas M. S., Sierra-Galan L. M., Siu S., Vallejo E., Valles M., Faraggi M., Sereegotov E., Ilic S., Ben-Rais N., Alaoui N. I., Taleb S., Myo K. P. P., Thu P. S., Ghimire R. K., Rajbanshi B., Barneveld P., Glaudemans A., Habets J., Koopmans K. P., Manders J., Pool S., Scholte A., Scholtens A., Slart R., Thimister P., Van Asperen E. -J., Veltman N., Verschure D., Wagenaar N., Edmond J., Ellis C., Johnson K., Keenan R., Kueh S. H., Occleshaw C., Sasse A., To A., Van Pelt N., Young C., Cuadra T., Vanegas H. B. R., Soli I. A., Issoufou D. M., Ayodele T., Madu C., Onimode Y., Efros-Monsen E., Forsdahl S. H., Dimmen J. -M. H., Jorgensen A., Krohn I., Lovhaugen P., Braten A. T., Al Dhuhli H., Al Kindi F., Al-Bulushi N., Jawa Z., Tag N., Afzal M. S., Fatima S., Younis M. N., Riaz M., Saadullah M., Herrera Y., Lenturut-Katal D., Vazquez M. C., Ortellado J., Akhter A., Cao D., Cheung S., Dai X., Gong L., Han D., Hou Y., Li C., Li T., Li D., Li S., Liu J., Liu H., Lu B., Ng M. Y., Sun K., Tang G., Wang J., Wang X., Wang Z. -Q., Wang Y., Wu J., Wu Z., Xia L., Xiao J., Xu L., Yang Y., Yin W., Yu J., Yuan L., Zhang T., Zhang L., Zhang Y. -G., Zhang X., Zhu L., Alfaro A., Abrihan P., Barroso A., Cruz E., Gomez M. R., Magboo V. P., Medina J. M., Obaldo J., Pastrana D., Pawhay C. M., Quinon A., Tang J. M., Tecson B., Uson K. J., Uy M., Kostkiewicz M., Kunikowska J., Bettencourt N., Cantinho G., Ferreira A., Syed G., Arnous S., Atyani S., Byrne A., Gleeson T., Kerins D., Meehan C., Murphy D., Murphy M., Murray J., O'Brien J., Bang J. -I., Bom H., Cho S. -G., Hong C. M., Jang S. J., Jeong Y. H., Kang W. J., Kim J. -Y., Namgung C. K., So Y., Won K. S., Majstorov V., Vavlukis M., Salobir B. G., Stalc M., Benedek T., Benedek I., Mititelu R., Stan C. A., Dariy O., Drozdova O., Gagarina N., Gulyaev V. M., Itskovich I., Karalkin A., Kokov A., Migunova E., Pospelov V., Ryzhkova D., Saifullina G., Sazonova S., Shurupova I., Trifonova T., Ussov W. Y., Vakhromeeva M., Valiullina N., Zavadovsky K., Zhuravlev K., Alasnag M., Okarvi S., Saranovic D. S., Keng F., See J. H. J., Sekar R., Yew M. S., Vondrak A., Bejai S., Bennie G., Bester R., Engelbrecht G., Evbuomwan O., Gongxeka H., Vuuren M. 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Decter, B, Dhruva, N, Doherty, N, Doukky, R, Dunbar, A, Duvall, W, Edwards, R, Esquitin, K, Farah, H, Fentanes, E, Ferencik, M, Fisher, D, Fitzpatrick, D, Foster, C, Fuisz, T, Gannon, M, Gastner, L, Gerson, M, Ghoshhajra, B, Goldberg, A, Goldner, B, Gonzalez, J, Gore, R, Gracia-Lopez, S, Hage, F, Haider, A, Haider, S, Hamirani, Y, Hassen, K, Hatfield, M, Hawkins, C, Hawthorne, K, Heath, N, Hendel, R, Hernandez, P, Hill, G, Horgan, S, Huffman, J, Hurwitz, L, Iskandrian, A, Janardhanan, R, Jellis, C, Jerome, S, Kalra, D, Kaviratne, S, Kay, F, Kelly, F, Khalique, O, Kinkhabwala, M, Iii, G, Kircher, J, Kirkbride, R, Kontos, M, Kottam, A, Krepp, J, Layer, J, Lee, S, Leppo, J, Lesser, J, Leung, S, Lewin, H, Litmanovich, D, Liu, Y, Lopez-Mattei, J, Magurany, K, Markowitz, J, Marn, A, Matis, S, Mckenna, M, Mcrae, T, Mendoza, F, Merhige, M, Min, D, Moffitt, C, Moncher, K, Moore, W, Morayati, S, Morris, M, Mossa-Basha, M, Mrsic, Z, Murthy, V, Nagpal, P, Napier, K, Narula, J, Nelson, K, Nijjar, P, Osman, M, Parwani, P, Passen, E, Patel, A, Patil, P, Paul, R, Phillips, L, Polsani, V, Poludasu, R, Pomerantz, B, Porter, T, Prentice, R, Pursnani, A, Rabbat, M, Ramamurti, S, Rich, F, Luna, H, Robinson, A, Robles, K, Rodriguez, C, Rorie, M, Rumberger, J, Russell, R, Sabra, P, Sadler, D, Schemmer, M, Schoepf, U, Shah, S, Shah, N, Shanbhag, S, Sharma, G, Shayani, S, Shirani, J, Shivaram, P, Sigman, S, Simon, M, Slim, A, Smith, D, Smith, A, Soman, P, Srichai-Parsia, M, Streeter, J, Albert, T, Tawakol, A, Thomas, D, Thompson, R, Torbet, T, Trinidad, D, Ullery, S, Unzek, S, Uretsky, S, Vallurupalli, S, Verma, V, Waller, A, Wang, E, Ward, P, Weissman, G, Wesbey, G, White, K, Winchester, D, Wolinsky, D, Yost, S, Zgaljardic, M, Alonso, O, Beretta, M, Ferrando, R, Kapitan, M, Mut, F, Djuraev, O, Rozikhodjaeva, G, Ngoc, H, Mai, S, Nguyen, X, Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE), Translational Immunology Groningen (TRIGR), and Cardiovascular Centre (CVC)
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INCAPS COVID Investigators Group ,cardiac imaging techniques ,Settore MED/11 - Malattie dell'Apparato Cardiovascolare ,Practice Patterns ,Disease ,Cardiovascular ,coronary artery disease ,COVID-19 ,Cardiac Imaging Techniques ,Cardiologists ,Europe ,Health Care Surveys ,Healthcare Disparities ,Heart Diseases ,Humans ,Practice Patterns, Physicians' ,Predictive Value of Tests ,Gross domestic product ,Human health ,cardiovascular disease ,Pandemic ,Medicine ,cardiovascular imaging ,BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Interna medicina ,cardiac imaging technique ,Predictive value of tests ,Cardiology and Cardiovascular Medicine ,BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Infektologija ,cardiac disease ,Coronavirus disease 2019 (COVID-19) ,Independent predictor ,cardiac imaging ,NO ,Imaging diagnosis ,Diseases of the circulatory (Cardiovascular) system ,BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Internal Medicine ,Physicians' ,business.industry ,BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Infectology ,RC666-701 ,HOSPITALIZATIONS ,business ,Health Care Delivery, Economics and Global Health Care ,Demography - Abstract
ObjectivesWe aimed to explore the impact of the COVID-19 pandemic on cardiac diagnostic testing and practice and to assess its impact in different regions in Europe.MethodsThe online survey organised by the International Atomic Energy Agency Division of Human Health collected information on changes in cardiac imaging procedural volumes between March 2019 and March/April 2020. Data were collected from 909 centres in 108 countries.ResultsCentres in Northern and Southern Europe were more likely to cancel all outpatient activities compared with Western and Eastern Europe. There was a greater reduction in total procedure volumes in Europe compared with the rest of the world in March 2020 (45% vs 41%, p=0.003), with a more marked reduction in Southern Europe (58%), but by April 2020 this was similar in Europe and the rest of the world (69% vs 63%, p=0.261). Regional variations were apparent between imaging modalities, but the largest reductions were in Southern Europe for nearly all modalities. In March 2020, location in Southern Europe was the only independent predictor of the reduction in procedure volume. However, in April 2020, lower gross domestic product and higher COVID-19 deaths were the only independent predictors.ConclusionThe first wave of the COVID-19 pandemic had a significant impact on care of patients with cardiac disease, with substantial regional variations in Europe. This has potential long-term implications for patients and plans are required to enable the diagnosis of non-COVID-19 conditions during the ongoing pandemic.
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- 2021
25. Functional and molecular correlative imaging in a patient with amyloidosis
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Pagourelias, E., Delforge, M., Claus, P., and Gheysens, O.
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- 2016
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26. Mycobacterium genavense infection in a solid organ recipient: a diagnostic and therapeutic challenge
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Ombelet, S., Van Wijngaerden, E., Lagrou, K., Tousseyn, T., Gheysens, O., Droogne, W., Doubel, P., Kuypers, D., and Claes, K. J.
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- 2016
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27. Perspectives on joint EANM/SNMMI/ANZSNM practice guidelines/procedure standards for [18F]FDG PET/CT imaging during immunomodulatory treatments in patients with solid tumors.
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Lopci, E., Aide, N., Dimitrakopoulou-Strauss, A., Dercle, L., Iravani, A., Seban, R. D., Sachpekidis, C., Humbert, O., Gheysens, O., Glaudemans, A. W. J. M., Weber, W. A., Van den Abbeele, A. D., Wahl, R. L., Scott, A. M., Pandit-Taskar, N., and Hicks, R. J.
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- 2022
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28. Poster session 5: Friday 5 December 2014, 14: 00–18: 00Location: Poster area
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Turco, A, Duchenne, J, Nuyts, J, Gheysens, O, Voigt, J-U, Claus, P, and Vunckx, K
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- 2014
29. Semi-Quantitative Characterization of Post-Transplant Lymphoproliferative Disorder Morphological Subtypes with [F]FDG PET/CT
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Montes de Jesus, Felipe, Vergote, V, Noordzij, W, Dierickx, D, Dierckx, R A J O, Diepstra, A, Tousseyn, T, Gheysens, O, Kwee, T C, Deroose, C M, Glaudemans, A W J M, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Service de médecine nucléaire, and UCL - (SLuc) Centre du cancer
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surgical procedures, operative ,2-[18F]fluoro-2-deoxy-D-glucose positron emission tomography ,hemic and lymphatic diseases ,standardized uptake value ,semi-quantification ,post-transplant lymphoproliferative disorder ,FDG-PET/CT - Abstract
Post-transplant lymphoproliferative disorder (PTLD) is a complication of organ transplantation classified according to the WHO as nondestructive, polymorphic, monomorphic, and classic Hodgkin Lymphoma subtypes. In this retrospective study, we investigated the potential of semi-quantitative 2-[F]fluoro-2-deoxy-D-glucose ([F]FDG) PET/computed tomography (CT)-based parameters to differentiate between the PTLD morphological subtypes. 96 patients with histopathologically confirmed PTLD and baseline [F]FDG PET/CT between 2009 and 2019 were included. Extracted semi-quantitative measurements included: Maximum, peak, and mean standardized uptake value (SUV, SUV, and SUV). Median SUVs were highest for monomorphic PTLD followed by polymorphic and nondestructive subtypes. The median SUV at the biopsy site was significantly higher in monomorphic PTLD (17.8, interquartile range (IQR):16) than in polymorphic subtypes (9.8, IQR:13.4) and nondestructive (4.1, IQR:6.1) ( = 0.04 and ≤ 0.01, respectively). An SUV ≥ 24.8 was always indicative of a monomorphic PTLD in our dataset. Nevertheless, there was a considerable overlap in SUV across the different morphologies. The median SUV at the biopsy site was significantly higher in monomorphic PTLD than polymorphic and nondestructive subtypes. However, due to significant SUV overlap across the different subtypes, these values may only serve as an indication of PTLD morphology, and SUV-based parameters cannot replace histopathological classification.
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- 2021
30. Impact of COVID-19 Pandemic on Cardiovascular Testing in Asia: The IAEA INCAPS-COVID Study
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Kudo, T., Lahey, R., Hirschfeld, C.B., Williams, M.C., Lu, B., Alasnag, M., Bhatia, M., Henry Bom, H.-., Dautov, T., Fazel, R., Karthikeyan, G., Keng, F.Y.J., Rubinshtein, R., Better, N., Cerci, R.J., Dorbala, S., Raggi, P., Shaw, L.J., Villines, T.C., Vitola, J.V., Choi, A.D., Malkovskiy, E., Goebel, B., Cohen, Y.A., Randazzo, M., Pascual, T.N.B., Pynda, Y., Dondi, M., Paez, D., Einstein, A.J., Cerci, R., Hinterleitner, G., Lu, Y., Morozova, O., Xu, Z., Cohen, Y., Choi, A., Lopez-Mattei, J., Parwani, P., Nasery, M.N., Goda, A., Shirka, E., Benlabgaa, R., Bouyoucef, S., Medjahedi, A., Nailli, Q., Agolti, M., Aguero, R.N., Alak, M.D.C., Alberguina, L.G., Arronada, G., Astesiano, A., Norton, C.B., Benteo, P., Blanco, J., Bonelli, J.M., Bustos, J.J., Cabrejas, R., Cachero, J., Campisi, R., Canderoli, A., Carames, S., Carrascosa, P., Castro, R., Cendoya, O., Cognigni, L.M., Collaud, C., Cortes, C., Courtis, J., Cragnolino, D., Daicz, M., De La Vega, A., De Maria, S.T., Del Riego, H., Dettori, F., Deviggiano, A., Dragonetti, L., Embon, M., Enriquez, R.E., Ensinas, J., Faccio, F., Facello, A., Garofalo, D., Geronazzo, R., Gonza, N., Gutierrez, L., Guzzo, M.A., Hasbani, V., Huerin, M., Jager, V., Lewkowicz, J.M., Lopez De Munain, M.N.A., Lotti, J.M., Marquez, A., Masoli, O., Masoli, O.H., Mastrovito, E., Mayoraz, M., Melado, G.E., Mele, A., Merani, M.F., Meretta, A.H., Molteni, S., Montecinos, M., Noguera, E., Novoa, C., Sueldo, C.P., Ascani, S.P., Pollono, P., Pujol, M.P., Radzinschi, A., Raimondi, G., Redruello, M., Rodriguez, M., Romero, R.L., Acuna, A.R., Rovaletti, F., San Miguel, L., Solari, L., Strada, B., Traverso, S., Traverzo, S.S., Espeche, M.D.H.V., Weihmuller, J.S., Wolcan, J., Zeffiro, S., Sakanyan, M., Beuzeville, S., Boktor, R., Butler, P., Calcott, J., Carr, L., Chan, V., Chao, C., Chong, W., Dobson, M., Downie, D.A., Dwivedi, G., Elison, B., Engela, J., Francis, R., Gaikwad, A., Basavaraj, A.G., Goodwin, B., Greenough, R., Hamilton-Craig, C., Hsieh, V., Joshi, S., Lederer, K., Lee, K., Lee, J., Magnussen, J., Mai, N., Mander, G., Murton, F., Nandurkar, D., Neill, J., O'Rourke, E., O'Sullivan, P., Pandos, G., Pathmaraj, K., Pitman, A., Poulter, R., Premaratne, M., Prior, D., Ridley, L., Rutherford, N., Salehi, H., Saunders, C., Scarlett, L., Seneviratne, S., Shetty, D., Shrestha, G., Shulman, J., Solanki, V., Stanton, T., Stuart, M., Stubbs, M., Swainson, I., Taubman, K., Taylor, A., Thomas, P., Unger, S., Upton, A., Vamadevan, S., Van Gaal, W., Verjans, J., Voutnis, D., Wayne, V., Wilson, P., Wong, D., Wong, K., Younger, J., Feuchtner, G., Mirzaei, S., Weiss, K., Maroz-Vadalazhskaya, N., Gheysens, O., Homans, F., Moreno-Reyes, R., Pasquet, A., Roelants, V., Van De Heyning, C.M., Rios, R.A., Soldat-Stankovic, V., Stankovic, S., Albernaz Siqueira, M.H., Almeida, A., Alves Togni, P.H., Andrade, J.H., Andrade, L., Anselmi, C., Araujo, R., Azevedo, G., Bezerra, S., Biancardi, R., Grossman, G.B., Brandao, S., Pianta, D.B., Carreira, L., Castro, B., Chang, T., Cunali, F., Cury, R., Dantas, R., de Amorim Fernandes, F., De Lorenzo, A., De Macedo Filho, R., Erthal, F., Fernandes, F., Fernandes, J., De Souza, T.F., Alves, W.F., Ghini, B., Goncalves, L., Gottlieb, I., Hadlich, M., Kameoka, V., Lima, R., Lima, A., Lopes, R.W., Machado e Silva, R., Magalhaes, T., Silva, F.M., Mastrocola, L.E., Medeiros, F., Meneghetti, J.C., Naue, V., Naves, D., Nolasco, R., Nomura, C., Oliveira, J.B., Paixao, E., De Carvalho, F.P., Pinto, I., Possetti, P., Quinta, M., Nogueira Ramos, R.R., Rocha, R., Rodrigues, A., Rodrigues, C., Romantini, L., Sanches, A., Santana, S., Sara da Silva, L., Schvartzman, P., Matushita, C.S., Senra, T., Shiozaki, A., Menezes de Siqueira, M.E., Siqueira, C., Smanio, P., Soares, C.E., Junior, J.S., Bittencourt, M.S., Spiro, B., Mesquita, C.T., Torreao, J., Torres, R., Uellendahl, M., Monte, G.U., Verissimo, O., Cabeda, E.V., Pedras, F.V., Waltrick, R., Zapparoli, M., Naseer, H., Garcheva-Tsacheva, M., Kostadinova, 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Gormsen, L.C., Hasbak, P., Hess, S., Holdgaard, P., Johansen, A., Kyhl, K., Norgaard, B.L., Ovrehus, K.A., Ronnow Sand, N.P., Steffensen, R., Thomassen, A., Zerahn, B., Perez, A., Escorza Velez, G.A., Velez, M.S., Abdel Aziz, I.S., Abougabal, M., Ahmed, T., Allam, A., Asfour, A., Hassan, M., Hassan, A., Ibrahim, A., Kaffas, S., Kandeel, A., Ali, M.M., Mansy, A., Maurice, H., Nabil, S., Shaaban, M., Flores, A.C., Poksi, A., Knuuti, J., Kokkonen, V., Larikka, M., Uusitalo, V., Bailly, M., Burg, S., Deux, J.-., Habouzit, V., Hyafil, F., Lairez, O., Proffit, F., Regaieg, H., Sarda-Mantel, L., Tacher, V., Schneider, R.P., Ayetey, H., Angelidis, G., Archontaki, A., Chatziioannou, S., Datseris, I., Fragkaki, C., Georgoulias, P., Koukouraki, S., Koutelou, M., Kyrozi, E., Repasos, E., Stavrou, P., Valsamaki, P., Gonzalez, C., Gutierrez, G., Maldonado, A., Buga, K., Garai, I., Maurovich-Horvat, P., Schmidt, E., Szilveszter, B., Varady, E., Banthia, N., Bhagat, J.K., Bhargava, R., Bhat, V., Choudhury, P., Chowdekar, V.S., Irodi, A., Jain, S., Joseph, E., Kumar, S., Girijanandan Mahapatra, P.D., Mitra, D., Mittal, B.R., Ozair, A., Patel, C., Patel, T., Patel, R., Patel, S., Saxena, S., Sengupta, S., Singh, S., Singh, B., Sood, A., Verma, A., Affandi, E., Alam, P.S., Edison, E., Gunawan, G., Hapkido, H., Hidayat, B., Huda, A., Mukti, A.P., Prawiro, D., Soeriadi, E.A., Syawaluddin, H., Albadr, A., Assadi, M., Emami, F., Houshmand, G., Maleki, M., Rostami, M.T., Zakavi, S.R., Zaid, E.A., Agranovich, S., Arnson, Y., Bar-Shalom, R., Frenkel, A., Knafo, G., Lugassi, R., Maor Moalem, I.S., Mor, M., Muskal, N., Ranser, S., Shalev, A., Albano, D., Alongi, P., Arnone, G., Bagatin, E., Baldari, S., Bauckneht, M., Bertelli, P., Bianco, F., Bonfiglioli, R., Boni, R., Bruno, A., Bruno, I., Busnardo, E., Califaretti, E., Camoni, L., Carnevale, A., Casoni, R., Cavallo, A.U., Cavenaghi, G., Chierichetti, F., Chiocchi, M., Cittanti, C., Colletta, M., Conti, U., Cossu, A., Cuocolo, A., Cuzzocrea, M., De Rimini, M.L., De Vincentis, G., Del Giudice, E., Del Torto, A., Della Tommasina, V., Durmo, R., Erba, P.A., Evangelista, L., Faletti, R., Faragasso, E., Farsad, M., Ferro, P., Florimonte, L., Frantellizzi, V., Fringuelli, F.M., Gatti, M., Gaudiano, A., Gimelli, A., Giubbini, R., Giuffrida, F., Ialuna, S., Laudicella, R., Leccisotti, L., Leva, L., Liga, R., Liguori, C., Longo, G., Maffione, M., Mancini, M.E., Marcassa, C., Milan, E., Nardi, B., Pacella, S., Pepe, G., Pontone, G., Pulizzi, S., Quartuccio, N., Rampin, L., Ricci, F., Rossini, P., Rubini, G., Russo, V., Sacchetti, G.M., Sambuceti, G., Scarano, M., Sciagra, R., Sperandio, M., Stefanelli, A., Ventroni, G., Zoboli, S., Baugh, D., Chambers, D., Madu, E., Nunura, F., Asano, H., Chimura, C.M., Fujimoto, S., Fujisue, K., Fukunaga, T., Fukushima, Y., Fukuyama, K., Hashimoto, J., Ichikawa, Y., Iguchi, N., Imai, M., Inaki, A., Ishimura, H., Isobe, S., Kadokami, T., Kato, T., Kumita, S., Maruno, H., Mataki, H., 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Ornelas, M., Ortga Ramirez, J.A., Preciado-Anaya, A., Preciado-Gutierrez, O.U., Barragan, A.P., Rosales Uvera, S.G., Sandoval, S., Tomas, M.S., Sierra-Galan, L.M., Siu, S., Vallejo, E., Valles, M., Faraggi, M., Sereegotov, E., Ilic, S., Ben-Rais, N., Alaoui, N.I., Taleb, S., Pa Myo, K.P., Thu, P.S., Ghimire, R.K., Rajbanshi, B., Barneveld, P., Glaudemans, A., Habets, J., Koopmans, K.P., Manders, J., Pool, S., Scholte, A., Scholtens, A., Slart, R., Thimister, P., Van Asperen, E.-., Veltman, N., Verschure, D., Wagenaar, N., Edmond, J., Ellis, C., Johnson, K., Keenan, R., Kueh, S.H.A., Occleshaw, C., Sasse, A., To, A., Van Pelt, N., Young, C., Cuadra, T., Roque Vanegas, H.B., Soli, I.A., Issoufou, D.M., Ayodele, T., Madu, C., Onimode, Y., Efros-Monsen, E., Forsdahl, S.H., Hildre Dimmen, J.-., Jorgensen, A., Krohn, I., Lovhaugen, P., Braten, A.T., Al Dhuhli, H., Al Kindi, F., Al-Bulushi, N., Jawa, Z., Tag, N., Afzal, M.S., Fatima, S., Younis, M.N., Riaz, M., Saadullah, M., Herrera, Y., Lenturut-Katal, D., Vazquez, M.C., Ortellado, J., Akhter, A., Cao, D., Cheung, S., Dai, X., Gong, L., Han, D., Hou, Y., Li, C., Li, T., Li, D., Li, S., Liu, J., Liu, H., M. Y., N., Sun, K., Tang, G., Wang, J., Wang, X., Wang, Z.-., Wang, Y., Wu, J., Wu, Z., Xia, L., Xiao, J., Xu, L., Yang, Y., Yin, W., Yu, J., Yuan, L., Zhang, T., Zhang, L., Zhang, Y.-., Zhang, X., Zhu, L., Alfaro, A., Abrihan, P., Barroso, A., Cruz, E., Gomez, M.R., Magboo, V.P., Medina, J.M., Obaldo, J., Pastrana, D., Pawhay, C.M., Quinon, A., Tang, J.M., Tecson, B., Uson, K.J., Uy, M., Kostkiewicz, M., Kunikowska, J., Bettencourt, N., Cantinho, G., Ferreira, A., Syed, G., Arnous, S., Atyani, S., Byrne, A., Gleeson, T., Kerins, D., Meehan, C., Murphy, D., Murphy, M., Murray, J., O'Brien, J., Bang, J.-., Bom, H., Cho, S.-., Hong, C.M., Jang, S.J., Jeong, Y.H., Kang, W.J., Kim, J.-., Namgung, C.K., So, Y., Won, K.S., Majstorov, V., Vavlukis, M., Salobir, B.G., Stalc, M., Benedek, T., Benedek, I., Mititelu, R., Stan, C.A., Ansheles, A., Dariy, O., Drozdova, O., Gagarina, N., Gulyaev, V.M., Itskovich, I., Karalkin, A., Kokov, A., Migunova, E., Pospelov, V., Ryzhkova, D., Saifullina, G., Sazonova, S., Sergienko, V., Shurupova, I., Trifonova, T., Ussov, W.Y., Vakhromeeva, M., Valiullina, N., Zavadovsky, K., Zhuravlev, K., Okarvi, S., Saranovic, D.S., Keng, F., Jason See, J.H., Sekar, R., Yew, M.S., Vondrak, A., Bejai, S., Bennie, G., Bester, R., Engelbrecht, G., Evbuomwan, O., Gongxeka, H., Vuuren, M.J., Kaplan, M., Khushica, P., Lakhi, H., Louw, L., Malan, N., Milos, K., Modiselle, M., More, S., Naidoo, M., Scholtz, L., Vangu, M., Aguade-Bruix, S., Blanco, I., Cabrera, A., Camarero, A., Casans-Tormo, I., Cuellar-Calabria, H., Flotats, A., Fuentes Canamero, M.E., Garcia, M.E., Jimenez-Heffernan, A., Leta, R., Diaz, J.L., Lumbreras, L., Marquez-Cabeza, J.J., Martin, F., Martinez de Alegria, A., Medina, F., Canal, M.P., Peiro, V., Pubul-Nunez, V., Rayo Madrid, J.I., Rey, C.R., Perez, R.R., Ruiz, J., Hernandez, G.S., Sevilla, A., Zeidan, N., Nanayakkara, D., Udugama, C., Simonsson, M., Alkadhi, H., Buechel, R.R., Burger, P., Ceriani, L., De Boeck, B., Grani, C., Juillet de Saint Lager Lucas, A., Kamani, C.H., Kawel-Boehm, N., Manka, R., Prior, J.O., Rominger, A., Vallee, J.-., Khiewvan, B., Premprabha, T., Thientunyakit, T., Sellem, A., Kir, K.M., Sayman, H., Sebikali, M.J., Muyinda, Z., Kmetyuk, Y., Korol, P., Mykhalchenko, O., Pliatsek, V., Satyr, M., Albalooshi, B., Ahmed Hassan, M.I., Anderson, J., Bedi, P., Biggans, T., Bularga, A., Bull, R., Burgul, R., Carpenter, J.-., Coles, D., Cusack, D., Deshpande, A., Dougan, J., Fairbairn, T., Farrugia, A., Gopalan, D., Gummow, A., Ramkumar, P.G., Hamilton, M., Harbinson, M., Hartley, T., Hudson, B., Joshi, N., Kay, M., Kelion, A., Khokhar, A., Kitt, J., Low, C., Mak, S.M., Marousa, N., Martin, J., Mcalindon, E., Menezes, L., Morgan-Hughes, G., Moss, A., Murray, A., Nicol, E., Patel, D., Peebles, C., Pugliese, F., Luis Rodrigues, J.C., Rofe, C., Sabharwal, N., Schofield, R., Semple, T., Sharma, N., Strouhal, P., Subedi, D., Topping, W., Tweed, K., Weir-Mccall, J., Abbara, S., Abbasi, T., Abbott, B., Abohashem, S., Abramson, S., Al-Abboud, T., Al-Mallah, M., Almousalli, O., Ananthasubramaniam, K., Kumar, M.A., Askew, J., Attanasio, L., Balmer-Swain, M., Bayer, R.R., Bernheim, A., Bhatti, S., Bieging, E., Blankstein, R., Bloom, S., Blue, S., Bluemke, D., Borges, A., Branch, K., Bravo, P., Brothers, J., Budoff, M., Bullock-Palmer, R., Burandt, A., Burke, F.W., Bush, K., Candela, C., Capasso, E., Cavalcante, J., Chang, D., Chatterjee, S., Chatzizisis, Y., Cheezum, M., Chen, T., Chen, J., Chen, M., Clarcq, J., Cordero, A., Crim, M., Danciu, S., Decter, B., Dhruva, N., Doherty, N., Doukky, R., Dunbar, A., Duvall, W., Edwards, R., Esquitin, K., Farah, H., Fentanes, E., Ferencik, M., Fisher, D., Fitzpatrick, D., Foster, C., Fuisz, T., Gannon, M., Gastner, L., Gerson, M., Ghoshhajra, B., Goldberg, A., Goldner, B., Gonzalez, J., Gore, R., Gracia-Lopez, S., Hage, F., Haider, A., Haider, S., Hamirani, Y., Hassen, K., Hatfield, M., Hawkins, C., Hawthorne, K., Heath, N., Hendel, R., Hernandez, P., Hill, G., Horgan, S., Huffman, J., Hurwitz, L., Iskandrian, A., Janardhanan, R., Jellis, C., Jerome, S., Kalra, D., Kaviratne, S., Kay, F., Kelly, F., Khalique, O., Kinkhabwala, M., Iii, G.K., Kircher, J., Kirkbride, R., Kontos, M., Kottam, A., Krepp, J., Layer, J., Lee, S.H., Leppo, J., Lesser, J., Leung, S., Lewin, H., Litmanovich, D., Liu, Y., Magurany, K., Markowitz, J., Marn, A., Matis, S.E., Mckenna, M., Mcrae, T., Mendoza, F., Merhige, M., Min, D., Moffitt, C., Moncher, K., Moore, W., Morayati, S., Morris, M., Mossa-Basha, M., Mrsic, Z., Murthy, V., Nagpal, P., Napier, K., Nelson, K., Nijjar, P., Osman, M., Passen, E., Patel, A., Patil, P., Paul, R., Phillips, L., Polsani, V., Poludasu, R., Pomerantz, B., Porter, T., Prentice, R., Pursnani, A., Rabbat, M., Ramamurti, S., Rich, F., Luna, H.R., Robinson, A., Robles, K., Rodriguez, C., Rorie, M., Rumberger, J., Russell, R., Sabra, P., Sadler, D., Schemmer, M., Schoepf, U.J., Shah, S., Shah, N., Shanbhag, S., Sharma, G., Shayani, S., Shirani, J., Shivaram, P., Sigman, S., Simon, M., Slim, A., Smith, D., Smith, A., Soman, P., Srichai-Parsia, M.B., Streeter, J., T, A., Tawakol, A., Thomas, D., Thompson, R., Torbet, T., Trinidad, D., Ullery, S., Unzek, S., Uretsky, S., Vallurupalli, S., Verma, V., Waller, A., Wang, E., Ward, P., Weissman, G., Wesbey, G., White, K., Winchester, D., Wolinsky, D., Yost, S., Zgaljardic, M., Alonso, O., Beretta, M., Ferrando, R., Kapitan, M., Mut, F., Djuraev, O., Rozikhodjaeva, G., Le Ngoc, H., Mai, S.H., and Nguyen, X.C.
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INCAPS COVID Investigators Group ,Pediatric Research Initiative ,positron emission tomography ,CTA ,SARS-CoV-2 ,cardiac testing ,invasive coronary angiography ,Prevention ,coronavirus ,coronavirus disease-19 ,COVID-19 ,global health ,Settore MED/11 - Malattie dell'Apparato Cardiovascolare ,cardiac magnetic resonance ,cardiovascular disease ,NO ,transthoracic echocardiography ,PET ,Good Health and Well Being ,severe acute respiratory syndrome-coronavirus-2 ,TTE ,ICA ,CMR ,computed tomographic angiography - Abstract
BackgroundThe coronavirus disease-2019 (COVID-19) pandemic significantly affected management of cardiovascular disease around the world. The effect of the pandemic on volume of cardiovascular diagnostic procedures is not known.ObjectivesThis study sought to evaluate the effects of the early phase of the COVID-19 pandemic on cardiovascular diagnostic procedures and safety practices in Asia.MethodsThe International Atomic Energy Agency conducted a worldwide survey to assess changes in cardiovascular procedure volume and safety practices caused by COVID-19. Testing volumes were reported for March 2020 and April 2020 and were compared to those from March 2019. Data from 180 centers across 33 Asian countries were grouped into 4 subregions for comparison.ResultsProcedure volumes decreased by 47% from March 2019 to March 2020, showing recovery from March 2020 to April 2020 in Eastern Asia, particularly in China. The majority of centers cancelled outpatient activities and increased time per study. Practice changes included implementing physical distancing and restricting visitors. Although COVID testing was not commonly performed, it was conducted in one-third of facilities in Eastern Asia. The most severe reductions in procedure volumes were observed in lower-income countries, where volumes decreased 81% from March 2019 to April2020.ConclusionsThe COVID-19 pandemic in Asia caused significant reductions in cardiovascular diagnostic procedures, particularly in low-income countries. Further studies on effects of COVID-19 on cardiovascular outcomes and changes in care delivery are warranted.
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- 2021
31. The value of F-FDG PET/CT for the diagnosis of device-related infections in patients with a left ventricular assist device: a systematic review and meta-analysis
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Ten Hove, D, Treglia, G, Slart, R H J A, Damman, K, Wouthuyzen-Bakker, M, Postma, D F, Gheysens, O, Borra, R J H, Mecozzi, G, van Geel, P P, Sinha, B, Glaudemans, A W J M, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Centre du cancer, and UCL - (SLuc) Service de médecine nucléaire
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LVAD infection ,Meta-analysis ,Prosthesis-Related Infections ,Fluorodeoxyglucose F18 ,Positron Emission Tomography Computed Tomography ,Positron-Emission Tomography ,18F-FDG PET/CT ,Quality of Life ,Systematic review ,Humans ,Heart-Assist Devices ,Radiopharmaceuticals ,Sensitivity and Specificity - Abstract
Left ventricular assist devices (LVADs) are increasingly used for the treatment of advanced heart failure. LVADs improve quality of life and decrease mortality, but the driveline carries substantial risk for major infections. These device-related LVAD and driveline infections are difficult to diagnose with conventional imaging. We reviewed and analysed the current literature on the additive value of F-fluorodeoxyglucose positron emission tomography combined with computed tomography (FDG-PET/CT) imaging for the diagnosis of LVAD-related infections." We performed a systematic literature review using several databases from their inception until the 31st of December, 2019. Studies investigating the diagnostic performance of FDG-PET/CT in patients with suspected LVAD infection were retrieved. After a bias risk assessment using QUADAS-2, a study-aggregate meta-analysis was performed on a per examination-based analysis. A total of 10 studies were included in the systematic review, eight of which were also eligible for study-aggregate meta-analysis. For the meta-analysis, a total of 256 FDG-PET/CT scans, examining pump/pocket and/or driveline infection, were acquired in 230 patients. Pooled sensitivity of FDG-PET/CT was 0.95 (95% confidence interval (CI) 0.89-0.97) and pooled specificity was 0.91 (95% CI 0.54-0.99) for the diagnosis of device-related infection. For pump/pocket infection, sensitivity and specificity of FDG-PET/CT were 0.97 (95%CI 0.69-1.00) and 0.93 (95%CI 0.64-0.99), respectively. For driveline infection, sensitivity and specificity were 0.96 (95%CI 0.88-0.99) and 0.99 (95%CI 0.13-1.00) respectively. Significant heterogeneity existed across studies for specificity, mostly caused by differences in scan procedures. Predefined criteria for suspicion of LVAD and/or driveline infection were lacking in all included studies. FDG-PET/CT is a valuable tool for assessment of device-related infection in LVAD patients, with high sensitivity and high, albeit variable, specificity. Standardization of FDG-PET/CT procedures and criteria for suspected device-related LVAD infections are needed for consistent reporting of FDG-PET/CT scans.
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- 2021
32. The value of F-FDG PET/CT for the diagnosis of device-related infections in patients with a left ventricular assist device: a systematic review and meta-analysis.
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UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Centre du cancer, UCL - (SLuc) Service de médecine nucléaire, Ten Hove, D, Treglia, G, Slart, R H J A, Damman, K, Wouthuyzen-Bakker, M, Postma, D F, Gheysens, O, Borra, R J H, Mecozzi, G, van Geel, P P, Sinha, B, Glaudemans, A W J M, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Centre du cancer, UCL - (SLuc) Service de médecine nucléaire, Ten Hove, D, Treglia, G, Slart, R H J A, Damman, K, Wouthuyzen-Bakker, M, Postma, D F, Gheysens, O, Borra, R J H, Mecozzi, G, van Geel, P P, Sinha, B, and Glaudemans, A W J M
- Abstract
Left ventricular assist devices (LVADs) are increasingly used for the treatment of advanced heart failure. LVADs improve quality of life and decrease mortality, but the driveline carries substantial risk for major infections. These device-related LVAD and driveline infections are difficult to diagnose with conventional imaging. We reviewed and analysed the current literature on the additive value of F-fluorodeoxyglucose positron emission tomography combined with computed tomography (FDG-PET/CT) imaging for the diagnosis of LVAD-related infections." We performed a systematic literature review using several databases from their inception until the 31st of December, 2019. Studies investigating the diagnostic performance of FDG-PET/CT in patients with suspected LVAD infection were retrieved. After a bias risk assessment using QUADAS-2, a study-aggregate meta-analysis was performed on a per examination-based analysis. A total of 10 studies were included in the systematic review, eight of which were also eligible for study-aggregate meta-analysis. For the meta-analysis, a total of 256 FDG-PET/CT scans, examining pump/pocket and/or driveline infection, were acquired in 230 patients. Pooled sensitivity of FDG-PET/CT was 0.95 (95% confidence interval (CI) 0.89-0.97) and pooled specificity was 0.91 (95% CI 0.54-0.99) for the diagnosis of device-related infection. For pump/pocket infection, sensitivity and specificity of FDG-PET/CT were 0.97 (95%CI 0.69-1.00) and 0.93 (95%CI 0.64-0.99), respectively. For driveline infection, sensitivity and specificity were 0.96 (95%CI 0.88-0.99) and 0.99 (95%CI 0.13-1.00) respectively. Significant heterogeneity existed across studies for specificity, mostly caused by differences in scan procedures. Predefined criteria for suspicion of LVAD and/or driveline infection were lacking in all included studies. FDG-PET/CT is a valuable tool for assessment of device-related infection in LVAD patients, with high sensitivity and high, albeit variable, s
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- 2021
33. Prognostic superiority of International Prognostic Index over [F]FDG PET/CT volumetric parameters in post-transplant lymphoproliferative disorder.
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UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Centre du cancer, UCL - (SLuc) Service de médecine nucléaire, Montes de Jesus, F, Dierickx, D, Vergote, V, Noordzij, W, Dierckx, R A J O, Deroose, C M, Glaudemans, A W J M, Gheysens, O, Kwee, T C, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Centre du cancer, UCL - (SLuc) Service de médecine nucléaire, Montes de Jesus, F, Dierickx, D, Vergote, V, Noordzij, W, Dierckx, R A J O, Deroose, C M, Glaudemans, A W J M, Gheysens, O, and Kwee, T C
- Abstract
Post-transplant lymphoproliferative disorders (PTLDs) are a spectrum of hematological malignancies occurring after solid organ and hematopoietic stem cell transplantation. [F]FDG PET/CT is routinely performed at PTLD diagnosis, allowing for both staging of the disease and quantification of volumetric parameters, such as whole-body metabolic tumor volume (MTV) and total lesion glycolysis (TLG). In this retrospective study, we aimed to determine the prognostic value of MTV and TLG in PTLD patients, together with other variables of interest, such as the International Prognostic Index (IPI), organ transplant type, EBV tumor status, time after transplant, albumin levels and PTLD morphology. A total of 88 patients were included. The 1-, 3-, 5- year overall survival rates were 67%, 58% and 43% respectively. Multivariable analysis indicated that a high IPI (HR: 1.56, 95% CI: 1.13-2.16) and an EBV-negative tumor (HR: 2.71, 95% CI: 1.38-5.32) were associated with poor overall survival. Patients with a kidney transplant had a longer overall survival than any other organ recipients (HR: 0.38 95% CI: 0.16-0.89). IPI was found to be the best predicting parameter of overall survival in our cohort. Whole-body MTV, TLG, time after transplant, hypoalbuminemia and PTLD morphology were not associated with overall survival. [F]FDG PET/CT whole-body volumetric quantitative parameters were not predictive of overall survival in PTLD. In our cohort, high IPI and an EBV-negative tumor were found to predictors of worse overall survival while kidney transplant patients had a longer overall survival compared to other organ transplant recipients.
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- 2021
34. Semi-Quantitative Characterization of Post-Transplant Lymphoproliferative Disorder Morphological Subtypes with [F]FDG PET/CT.
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UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Service de médecine nucléaire, UCL - (SLuc) Centre du cancer, Montes de Jesus, Felipe, Vergote, V, Noordzij, W, Dierickx, D, Dierckx, R A J O, Diepstra, A, Tousseyn, T, Gheysens, O, Kwee, T C, Deroose, C M, Glaudemans, A W J M, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Service de médecine nucléaire, UCL - (SLuc) Centre du cancer, Montes de Jesus, Felipe, Vergote, V, Noordzij, W, Dierickx, D, Dierckx, R A J O, Diepstra, A, Tousseyn, T, Gheysens, O, Kwee, T C, Deroose, C M, and Glaudemans, A W J M
- Abstract
Post-transplant lymphoproliferative disorder (PTLD) is a complication of organ transplantation classified according to the WHO as nondestructive, polymorphic, monomorphic, and classic Hodgkin Lymphoma subtypes. In this retrospective study, we investigated the potential of semi-quantitative 2-[F]fluoro-2-deoxy-D-glucose ([F]FDG) PET/computed tomography (CT)-based parameters to differentiate between the PTLD morphological subtypes. 96 patients with histopathologically confirmed PTLD and baseline [F]FDG PET/CT between 2009 and 2019 were included. Extracted semi-quantitative measurements included: Maximum, peak, and mean standardized uptake value (SUV, SUV, and SUV). Median SUVs were highest for monomorphic PTLD followed by polymorphic and nondestructive subtypes. The median SUV at the biopsy site was significantly higher in monomorphic PTLD (17.8, interquartile range (IQR):16) than in polymorphic subtypes (9.8, IQR:13.4) and nondestructive (4.1, IQR:6.1) ( = 0.04 and ≤ 0.01, respectively). An SUV ≥ 24.8 was always indicative of a monomorphic PTLD in our dataset. Nevertheless, there was a considerable overlap in SUV across the different morphologies. The median SUV at the biopsy site was significantly higher in monomorphic PTLD than polymorphic and nondestructive subtypes. However, due to significant SUV overlap across the different subtypes, these values may only serve as an indication of PTLD morphology, and SUV-based parameters cannot replace histopathological classification.
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- 2021
35. Diagnostic value of [18F]FDG-PET/CT in polymyalgia rheumatica: a systematic review and meta-analysis.
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UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Centre du cancer, UCL - (SLuc) Service de médecine nucléaire, UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie, van der Geest, K S M, Treglia, G, Glaudemans, A W J M, Brouwer, E, Jamar, F, Slart, R H J A, Gheysens, O, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Centre du cancer, UCL - (SLuc) Service de médecine nucléaire, UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie, van der Geest, K S M, Treglia, G, Glaudemans, A W J M, Brouwer, E, Jamar, F, Slart, R H J A, and Gheysens, O
- Abstract
Polymyalgia rheumatica (PMR) can be difficult to diagnose. Whole-body [18F]FDG-PET/CT allows for a comprehensive evaluation of all relevant articular and extra-articular structures affected by PMR. We aimed to summarize current evidence on the diagnostic value of [18F]FDG-PET/CT for a diagnosis of PMR. PubMed/MEDLINE and the Cochrane Library database were searched from inception through May 31, 2020. Studies containing patients with PMR who underwent [18F]FDG-PET/CT were included. Screening and full-text review were performed by 3 investigators and data extraction by 2 investigators. Risk of bias was examined with the QUADAS-2 tool. Diagnostic test meta-analysis was performed with a bivariate model. Twenty studies were included in the systematic review, of which 9 studies (n = 636 patients) were eligible for meta-analysis. [18F]FDG positivity at the following sites was associated with a diagnosis of PMR: interspinous bursae (positive likelihood ratio (LR+) 4.00; 95% CI 1.84-8.71), hips (LR+ 2.91; 95% CI 2.09-4.05), ischial tuberosities (LR+ 2.86; 95% CI 1.91-4.28), shoulders (LR+ 2.57; 95% CI 1.24-5.32) and sternoclavicular joints (LR+ 2.31; 95% CI 1.33-4.02). Negative likelihood ratios (LR-) for these sites, as well as the greater trochanters, were all less than 0.50. Composite [18F]FDG-PET/CT scores, as reported in 3 studies, provided a pooled LR+ of 3.91 (95% CI 2.42-6.32) and LR- of 0.19 (95% CI 0.10-0.36). Moderate to high heterogeneity was observed across the studies, mainly due to differences in patient selection, scanning procedures and/or interpretation criteria. Significant [18F]FDG uptake at a combination of anatomic sites is informative for a diagnosis of PMR. [18F]FDG-PET/CT might be an important diagnostic tool in patients with suspected PMR. This study also highlights the need for adherence to published procedural recommendations and standardized interpretation criteria for the use of [18F]FDG-PET/CT in PMR.
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- 2021
36. The relation between cardiac 123I-mIBG scintigraphy and functional response 1 year after CRT implantation.
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UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Service de médecine nucléaire, UCL - (SLuc) Centre du cancer, Verschure, D O, Poel, E, De Vincentis, G, Frantellizzi, V, Nakajima, K, Gheysens, O, de Groot, J R, Verberne, H J, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Service de médecine nucléaire, UCL - (SLuc) Centre du cancer, Verschure, D O, Poel, E, De Vincentis, G, Frantellizzi, V, Nakajima, K, Gheysens, O, de Groot, J R, and Verberne, H J
- Abstract
Cardiac resynchronization therapy (CRT) is a disease-modifying therapy in patients with chronic heart failure (CHF). Current guidelines ascribe CRT eligibility on three parameters only: left ventricular ejection fraction (LVEF), QRS duration, and New York Heart Association (NYHA) functional class. However, one-third of CHF patients does not benefit from CRT. This study evaluated whether 123I-meta-iodobenzylguanidine (123I-mIBG) assessed cardiac sympathetic activity could optimize CRT patient selection. A total of 78 stable CHF subjects (age 66.8 ± 9.6 years, 73% male, LVEF 25.2 ± 6.7%, QRS duration 153 ± 23 ms, NYHA 2.2 ± 0.7) referred for CRT implantation were enrolled. Subjects underwent 123I-mIBG scintigraphy prior to implantation. Early and late heart-to-mediastinum (H/M) ratio and 123I-mIBG washout were calculated. CRT response was defined as either an increase of LVEF to >35%, any improvement in LVEF of >10%, QRS shortening to <150 ms, or improvement in NYHA class of >1 class. In 33 patients LVEF increased to >35%, QRS decreased <150 ms in 36 patients, and NYHA class decreased in 33 patients. Late H/M ratio and hypertension were independent predictors of LVEF improvement to >35% (P = 0.0014 and P = 0.0149, respectively). In addition, early H/M ratio, LVEF, and absence of diabetes mellitus (DM) were independent predictors for LVEF improvement by >10%. No independent predictors were found for QRS shortening to <150 ms or improvement in NYHA class. Early and late H/M ratio were independent predictors of CRT response when improvement of LVEF was used as measure of response. Therefore, cardiac 123I-mIBG scintigraphy may be used as a tool to optimize selection of subjects that might benefit from CRT.
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- 2021
37. Impact of COVID-19 Pandemic on Cardiovascular Testing in Asia
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Kudo, T, Lahey, R, Hirschfeld, C, Williams, M, Lu, B, Alasnag, M, Bhatia, M, Henry Bom, H, Dautov, T, Fazel, R, Karthikeyan, G, Keng, F, Rubinshtein, R, Better, N, Cerci, R, Dorbala, S, Raggi, P, Shaw, L, Villines, T, Vitola, J, Choi, A, Malkovskiy, E, Goebel, B, Cohen, Y, Randazzo, M, Pascual, T, Pynda, Y, Dondi, M, Paez, D, Einstein, A, Hinterleitner, G, Lu, Y, Morozova, O, Xu, Z, Lopez-Mattei, J, Parwani, P, Nasery, M, Goda, A, Shirka, E, Benlabgaa, R, Bouyoucef, S, Medjahedi, A, Nailli, Q, Agolti, M, Aguero, R, Alak, M, Alberguina, L, Arroñada, G, Astesiano, A, Norton, C, Benteo, P, Blanco, J, Bonelli, J, Bustos, J, Cabrejas, R, Cachero, J, Campisi, R, Canderoli, A, Carames, S, Carrascosa, P, Castro, R, Cendoya, O, Cognigni, L, Collaud, C, Cortes, C, Courtis, J, Cragnolino, D, Daicz, M, De La Vega, A, De Maria, S, Del Riego, H, Dettori, F, Deviggiano, A, Dragonetti, L, Embon, M, Enriquez, R, Ensinas, J, Faccio, F, Facello, A, Garofalo, D, Geronazzo, R, Gonza, N, Gutierrez, L, Guzzo, M, Hasbani, V, Huerin, M, Jäger, V, Lewkowicz, J, López De Munaín, M, Lotti, J, Marquez, A, Masoli, O, Mastrovito, E, Mayoraz, M, Melado, G, Mele, A, Merani, M, Meretta, A, Molteni, S, Montecinos, M, Noguera, E, Novoa, C, Sueldo, C, Ascani, S, Pollono, P, Pujol, M, Radzinschi, A, Raimondi, G, Redruello, M, Rodríguez, M, Romero, R, Acuña, A, Rovaletti, F, San Miguel, L, Solari, L, Strada, B, Traverso, S, Traverzo, S, Espeche, M, Weihmuller, J, Wolcan, J, Zeffiro, S, Sakanyan, M, Beuzeville, S, Boktor, R, Butler, P, Calcott, J, Carr, L, Chan, V, Chao, C, Chong, W, Dobson, M, Downie, D, Dwivedi, G, Elison, B, Engela, J, Francis, R, Gaikwad, A, Basavaraj, A, Goodwin, B, Greenough, R, Hamilton-Craig, C, Hsieh, V, Joshi, S, Lederer, K, Lee, K, Lee, J, Magnussen, J, Mai, N, Mander, G, Murton, F, Nandurkar, D, Neill, J, O'Rourke, E, O'Sullivan, P, Pandos, G, Pathmaraj, K, Pitman, A, Poulter, R, Premaratne, M, Prior, D, Ridley, L, Rutherford, N, Salehi, H, Saunders, C, Scarlett, L, Seneviratne, S, Shetty, D, Shrestha, G, Shulman, J, Solanki, V, Stanton, T, Stuart, M, Stubbs, M, Swainson, I, Taubman, K, Taylor, A, Thomas, P, Unger, S, Upton, A, Vamadevan, S, Van Gaal, W, Verjans, J, Voutnis, D, Wayne, V, Wilson, P, Wong, D, Wong, K, Younger, J, Feuchtner, G, Mirzaei, S, Weiss, K, Maroz-Vadalazhskaya, N, Gheysens, O, Homans, F, Moreno-Reyes, R, Pasquet, A, Roelants, V, Van De Heyning, C, Ríos, R, Soldat-Stankovic, V, Stankovic, S, Albernaz Siqueira, M, Almeida, A, Alves Togni, P, Andrade, J, Andrade, L, Anselmi, C, Araújo, R, Azevedo, G, Bezerra, S, Biancardi, R, Grossman, G, Brandão, S, Pianta, D, Carreira, L, Castro, B, Chang, T, Cunali, F, Cury, R, Dantas, R, de Amorim Fernandes, F, De Lorenzo, A, De Macedo Filho, R, Erthal, F, Fernandes, F, Fernandes, J, De Souza, T, Alves, W, Ghini, B, Goncalves, L, Gottlieb, I, Hadlich, M, Kameoka, V, Lima, R, Lima, A, Lopes, R, Machado e Silva, R, Magalhães, T, Silva, F, Mastrocola, L, Medeiros, F, Meneghetti, J, Naue, V, Naves, D, Nolasco, R, Nomura, C, Oliveira, J, Paixao, E, De Carvalho, F, Pinto, I, Possetti, P, Quinta, M, Nogueira Ramos, R, Rocha, R, Rodrigues, A, Rodrigues, C, Romantini, L, Sanches, A, Santana, S, Sara da Silva, L, Schvartzman, P, Matushita, C, Senra, T, Shiozaki, A, Menezes de Siqueira, M, Siqueira, C, Smanio, P, Soares, C, Junior, J, Bittencourt, M, Spiro, B, Mesquita, C, Torreao, J, Torres, R, Uellendahl, M, Monte, G, Veríssimo, O, Cabeda, E, Pedras, F, Waltrick, R, Zapparoli, M, Naseer, H, Garcheva-Tsacheva, M, Kostadinova, I, Theng, Y, Abikhzer, G, Barette, R, Chow, B, Dabreo, D, Friedrich, M, Garg, R, Hafez, M, Johnson, C, Kiess, M, Leipsic, J, Leung, E, Miller, R, Oikonomou, A, Probst, S, Roifman, I, Small, G, Tandon, V, Trivedi, A, White, J, Zukotynski, K, Canessa, J, Muñoz, G, Concha, C, Hidalgo, P, Lovera, C, Massardo, T, Vargas, L, Abad, P, Arturo, H, Ayala, S, Benitez, L, Cadena, A, Caicedo, C, Moncayo, A, Gomez, S, Gutierrez Villamil, C, Jaimes, C, Londoño, J, Londoño Blair, J, Pabon, L, Pineda, M, Rojas, J, Ruiz, D, Escobar, M, Vasquez, A, Vergel, D, Zuluaga, A, Gamboa, I, Castro, G, González, U, Baric, A, Batinic, T, Franceschi, M, Paar, M, Jukic, M, Medakovic, P, Persic, V, Prpic, M, Punda, A, Batista, J, Gómez Lauchy, J, Gutierrez, Y, Menéndez, R, Peix, A, Rochela, L, Panagidis, C, Petrou, I, Engelmann, V, Kaminek, M, Kincl, V, Lang, O, Simanek, M, Abdulla, J, Bøttcher, M, Christensen, M, Gormsen, L, Hasbak, P, Hess, S, Holdgaard, P, Johansen, A, Kyhl, K, Norgaard, B, Øvrehus, K, Rønnow Sand, N, Steffensen, R, Thomassen, A, Zerahn, B, Perez, A, Escorza Velez, G, Velez, M, Abdel Aziz, I, Abougabal, M, Ahmed, T, Allam, A, Asfour, A, Hassan, M, Hassan, A, Ibrahim, A, Kaffas, S, Kandeel, A, Ali, M, Mansy, A, Maurice, H, Nabil, S, Shaaban, M, Flores, A, Poksi, A, Knuuti, J, Kokkonen, V, Larikka, M, Uusitalo, V, Bailly, M, Burg, S, Deux, J, Habouzit, V, Hyafil, F, Lairez, O, Proffit, F, Regaieg, H, Sarda-Mantel, L, Tacher, V, Schneider, R, Ayetey, H, Angelidis, G, Archontaki, A, Chatziioannou, S, Datseris, I, Fragkaki, C, Georgoulias, P, Koukouraki, S, Koutelou, M, Kyrozi, E, Repasos, E, Stavrou, P, Valsamaki, P, Gonzalez, C, Gutierrez, G, Maldonado, A, Buga, K, Garai, I, Maurovich-Horvat, P, Schmidt, E, Szilveszter, B, Várady, E, Banthia, N, Bhagat, J, Bhargava, R, Bhat, V, Choudhury, P, Chowdekar, V, Irodi, A, Jain, S, Joseph, E, Kumar, S, Girijanandan Mahapatra, P, Mitra, D, Mittal, B, Ozair, A, Patel, C, Patel, T, Patel, R, Patel, S, Saxena, S, Sengupta, S, Singh, S, Singh, B, Sood, A, Verma, A, Affandi, E, Alam, P, Edison, E, Gunawan, G, Hapkido, H, Hidayat, B, Huda, A, Mukti, A, Prawiro, D, Soeriadi, E, Syawaluddin, H, Albadr, A, Assadi, M, Emami, F, Houshmand, G, Maleki, M, Rostami, M, Zakavi, S, Zaid, E, Agranovich, S, Arnson, Y, Bar-Shalom, R, Frenkel, A, Knafo, G, Lugassi, R, Maor Moalem, I, Mor, M, Muskal, N, Ranser, S, Shalev, A, Albano, D, Alongi, P, Arnone, G, Bagatin, E, Baldari, S, Bauckneht, M, Bertelli, P, Bianco, F, Bonfiglioli, R, Boni, R, Bruno, A, Bruno, I, Busnardo, E, Califaretti, E, Camoni, L, Carnevale, A, Casoni, R, Cavallo, A, Cavenaghi, G, Chierichetti, F, Chiocchi, M, Cittanti, C, Colletta, M, Conti, U, Cossu, A, Cuocolo, A, Cuzzocrea, M, De Rimini, M, De Vincentis, G, Del Giudice, E, Del Torto, A, Della Tommasina, V, Durmo, R, Erba, P, Evangelista, L, Faletti, R, Faragasso, E, Farsad, M, Ferro, P, Florimonte, L, Frantellizzi, V, Fringuelli, F, Gatti, M, Gaudiano, A, Gimelli, A, Giubbini, R, Giuffrida, F, Ialuna, S, Laudicella, R, Leccisotti, L, Leva, L, Liga, R, Liguori, C, Longo, G, Maffione, M, Mancini, M, Marcassa, C, Milan, E, Nardi, B, Pacella, S, Pepe, G, Pontone, G, Pulizzi, S, Quartuccio, N, Rampin, L, Ricci, F, Rossini, P, Rubini, G, Russo, V, Sacchetti, G, Sambuceti, G, Scarano, M, Sciagrà, R, Sperandio, M, Stefanelli, A, Ventroni, G, Zoboli, S, Baugh, D, Chambers, D, Madu, E, Nunura, F, Asano, H, Chimura, C, Fujimoto, S, Fujisue, K, Fukunaga, T, Fukushima, Y, Fukuyama, K, Hashimoto, J, Ichikawa, Y, Iguchi, N, Imai, M, Inaki, A, Ishimura, H, Isobe, S, Kadokami, T, Kato, T, Kumita, S, Maruno, H, Mataki, H, Miyagawa, M, Morimoto, R, Moroi, M, Nagamachi, S, Nakajima, K, Nakata, T, Nakazato, R, Nanasato, M, Naya, M, Norikane, T, Ohta, Y, Okayama, S, Okizaki, A, Otomi, Y, Otsuka, H, Saito, M, Sakata, S, Sarai, M, Sato, D, Shiraishi, S, Suwa, Y, Takanami, K, Takehana, K, Taki, J, Tamaki, N, Taniguchi, Y, Teragawa, H, Tomizawa, N, Tsujita, K, Umeji, K, Wakabayashi, Y, Yamada, S, Yamazaki, S, Yoneyama, T, Rawashdeh, M, Batyrkhanov, D, Makhdomi, K, Ombati, K, Alkandari, F, Garashi, M, Coie, T, Rajvong, S, Kalinin, A, Kalnina, M, Haidar, M, Komiagiene, R, Kviecinskiene, G, Mataciunas, M, Vajauskas, D, Picard, C, Karim, N, Reichmuth, L, Samuel, A, Allarakha, M, Naojee, A, Alexanderson-Rosas, E, Barragan, E, González-Montecinos, A, Cabada, M, Rodriguez, D, Carvajal-Juarez, I, Cortés, V, Cortés, F, De La Peña, E, Gama-Moreno, M, González, L, Ramírez, N, Jiménez-Santos, M, Matos, L, Monroy, E, Morelos, M, Ornelas, M, Ortga Ramirez, J, Preciado-Anaya, A, Preciado-Gutiérrez, Ó, Barragan, A, Rosales Uvera, S, Sandoval, S, Tomas, M, Sierra-Galan, L, Siu, S, Vallejo, E, Valles, M, Faraggi, M, Sereegotov, E, Ilic, S, Ben-Rais, N, Alaoui, N, Taleb, S, Pa Myo, K, Thu, P, Ghimire, R, Rajbanshi, B, Barneveld, P, Glaudemans, A, Habets, J, Koopmans, K, Manders, J, Pool, S, Scholte, A, Scholtens, A, Slart, R, Thimister, P, Van Asperen, E, Veltman, N, Verschure, D, Wagenaar, N, Edmond, J, Ellis, C, Johnson, K, Keenan, R, Kueh, S, Occleshaw, C, Sasse, A, To, A, Van Pelt, N, Young, C, Cuadra, T, Roque Vanegas, H, Soli, I, Issoufou, D, Ayodele, T, Madu, C, Onimode, Y, Efros-Monsen, E, Forsdahl, S, Hildre Dimmen, J, Jørgensen, A, Krohn, I, Løvhaugen, P, Bråten, A, Al Dhuhli, H, Al Kindi, F, Al-Bulushi, N, Jawa, Z, Tag, N, Afzal, M, Fatima, S, Younis, M, Riaz, M, Saadullah, M, Herrera, Y, Lenturut-Katal, D, Vázquez, M, Ortellado, J, Akhter, A, Cao, D, Cheung, S, Dai, X, Gong, L, Han, D, Hou, Y, Li, C, Li, T, Li, D, Li, S, Liu, J, Liu, H, Ng, M, Sun, K, Tang, G, Wang, J, Wang, X, Wang, Z, Wang, Y, Wu, J, Wu, Z, Xia, L, Xiao, J, Xu, L, Yang, Y, Yin, W, Yu, J, Yuan, L, Zhang, T, Zhang, L, Zhang, Y, Zhang, X, Zhu, L, Alfaro, A, Abrihan, P, Barroso, A, Cruz, E, Gomez, M, Magboo, V, Medina, J, Obaldo, J, Pastrana, D, Pawhay, C, Quinon, A, Tang, J, Tecson, B, Uson, K, Uy, M, Kostkiewicz, M, Kunikowska, J, Bettencourt, N, Cantinho, G, Ferreira, A, Syed, G, Arnous, S, Atyani, S, Byrne, A, Gleeson, T, Kerins, D, Meehan, C, Murphy, D, Murphy, M, Murray, J, O'Brien, J, Bang, J, Bom, H, Cho, S, Hong, C, Jang, S, Jeong, Y, Kang, W, Kim, J, Namgung, C, So, Y, Won, K, Majstorov, V, Vavlukis, M, Salobir, B, Štalc, M, Benedek, T, Benedek, I, Mititelu, R, Stan, C, Ansheles, A, Dariy, O, Drozdova, O, Gagarina, N, Gulyaev, V, Itskovich, I, Karalkin, A, Kokov, A, Migunova, E, Pospelov, V, Ryzhkova, D, Saifullina, G, Sazonova, S, Sergienko, V, Shurupova, I, Trifonova, T, Ussov, W, Vakhromeeva, M, Valiullina, N, Zavadovsky, K, Zhuravlev, K, Okarvi, S, Saranovic, D, Jason See, J, Sekar, R, Yew, M, Vondrak, A, Bejai, S, Bennie, G, Bester, R, Engelbrecht, G, Evbuomwan, O, Gongxeka, H, Vuuren, M, Kaplan, M, Khushica, P, Lakhi, H, Louw, L, Malan, N, Milos, K, Modiselle, M, More, S, Naidoo, M, Scholtz, L, Vangu, M, Aguadé-Bruix, S, Blanco, I, Cabrera, A, Camarero, A, Casáns-Tormo, I, Cuellar-Calabria, H, Flotats, A, Fuentes Cañamero, M, García, M, Jimenez-Heffernan, A, Leta, R, Diaz, J, Lumbreras, L, Marquez-Cabeza, J, Martin, F, Martinez de Alegria, A, Medina, F, Canal, M, Peiro, V, Pubul-Nuñez, V, Rayo Madrid, J, Rey, C, Perez, R, Ruiz, J, Hernández, G, Sevilla, A, Zeidán, N, Nanayakkara, D, Udugama, C, Simonsson, M, Alkadhi, H, Buechel, R, Burger, P, Ceriani, L, De Boeck, B, Gräni, C, Juillet de Saint Lager Lucas, A, Kamani, C, Kawel-Boehm, N, Manka, R, Prior, J, Rominger, A, Vallée, J, Khiewvan, B, Premprabha, T, Thientunyakit, T, Sellem, A, Kir, K, Sayman, H, Sebikali, M, Muyinda, Z, Kmetyuk, Y, Korol, P, Mykhalchenko, O, Pliatsek, V, Satyr, M, Albalooshi, B, Ahmed Hassan, M, Anderson, J, Bedi, P, Biggans, T, Bularga, A, Bull, R, Burgul, R, Carpenter, J, Coles, D, Cusack, D, Deshpande, A, Dougan, J, Fairbairn, T, Farrugia, A, Gopalan, D, Gummow, A, Ramkumar, P, Hamilton, M, Harbinson, M, Hartley, T, Hudson, B, Joshi, N, Kay, M, Kelion, A, Khokhar, A, Kitt, J, Low, C, Mak, S, Marousa, N, Martin, J, Mcalindon, E, Menezes, L, Morgan-Hughes, G, Moss, A, Murray, A, Nicol, E, Patel, D, Peebles, C, Pugliese, F, Luis Rodrigues, J, Rofe, C, Sabharwal, N, Schofield, R, Semple, T, Sharma, N, Strouhal, P, Subedi, D, Topping, W, Tweed, K, Weir-Mccall, J, Abbara, S, Abbasi, T, Abbott, B, Abohashem, S, Abramson, S, Al-Abboud, T, Al-Mallah, M, Almousalli, O, Ananthasubramaniam, K, Kumar, M, Askew, J, Attanasio, L, Balmer-Swain, M, Bayer, R, Bernheim, A, Bhatti, S, Bieging, E, Blankstein, R, Bloom, S, Blue, S, Bluemke, D, Borges, A, Branch, K, Bravo, P, Brothers, J, Budoff, M, Bullock-Palmer, R, Burandt, A, Burke, F, Bush, K, Candela, C, Capasso, E, Cavalcante, J, Chang, D, Chatterjee, S, Chatzizisis, Y, Cheezum, M, Chen, T, Chen, J, Chen, M, Clarcq, J, Cordero, A, Crim, M, Danciu, S, Decter, B, Dhruva, N, Doherty, N, Doukky, R, Dunbar, A, Duvall, W, Edwards, R, Esquitin, K, Farah, H, Fentanes, E, Ferencik, M, Fisher, D, Fitzpatrick, D, Foster, C, Fuisz, T, Gannon, M, Gastner, L, Gerson, M, Ghoshhajra, B, Goldberg, A, Goldner, B, Gonzalez, J, Gore, R, Gracia-López, S, Hage, F, Haider, A, Haider, S, Hamirani, Y, Hassen, K, Hatfield, M, Hawkins, C, Hawthorne, K, Heath, N, Hendel, R, Hernandez, P, Hill, G, Horgan, S, Huffman, J, Hurwitz, L, Iskandrian, A, Janardhanan, R, Jellis, C, Jerome, S, Kalra, D, Kaviratne, S, Kay, F, Kelly, F, Khalique, O, Kinkhabwala, M, Iii, G, Kircher, J, Kirkbride, R, Kontos, M, Kottam, A, Krepp, J, Layer, J, Lee, S, Leppo, J, Lesser, J, Leung, S, Lewin, H, Litmanovich, D, Liu, Y, Magurany, K, Markowitz, J, Marn, A, Matis, S, Mckenna, M, Mcrae, T, Mendoza, F, Merhige, M, Min, D, Moffitt, C, Moncher, K, Moore, W, Morayati, S, Morris, M, Mossa-Basha, M, Mrsic, Z, Murthy, V, Nagpal, P, Napier, K, Nelson, K, Nijjar, P, Osman, M, Passen, E, Patel, A, Patil, P, Paul, R, Phillips, L, Polsani, V, Poludasu, R, Pomerantz, B, Porter, T, Prentice, R, Pursnani, A, Rabbat, M, Ramamurti, S, Rich, F, Luna, H, Robinson, A, Robles, K, Rodríguez, C, Rorie, M, Rumberger, J, Russell, R, Sabra, P, Sadler, D, Schemmer, M, Schoepf, U, Shah, S, Shah, N, Shanbhag, S, Sharma, G, Shayani, S, Shirani, J, Shivaram, P, Sigman, S, Simon, M, Slim, A, Smith, D, Smith, A, Soman, P, Srichai-Parsia, M, Streeter, J, T, A, Tawakol, A, Thomas, D, Thompson, R, Torbet, T, Trinidad, D, Ullery, S, Unzek, S, Uretsky, S, Vallurupalli, S, Verma, V, Waller, A, Wang, E, Ward, P, Weissman, G, Wesbey, G, White, K, Winchester, D, Wolinsky, D, Yost, S, Zgaljardic, M, Alonso, O, Beretta, M, Ferrando, R, Kapitan, M, Mut, F, Djuraev, O, Rozikhodjaeva, G, Le Ngoc, H, Mai, S, Nguyen, X, Kudo, Takashi, Lahey, Ryan, Hirschfeld, Cole B., Williams, Michelle C., Lu, Bin, Alasnag, Mirvat, Bhatia, Mona, Henry Bom, Hee-Seung, Dautov, Tairkhan, Fazel, Reza, Karthikeyan, Ganesan, Keng, Felix Y. J., Rubinshtein, Ronen, Better, Nathan, Cerci, Rodrigo Julio, Dorbala, Sharmila, Raggi, Paolo, Shaw, Leslee J., Villines, Todd C., Vitola, João V., Choi, Andrew D., Malkovskiy, Eli, Goebel, Benjamin, Cohen, Yosef A., Randazzo, Michael, Pascual, Thomas N. B., Pynda, Yaroslav, Dondi, Maurizio, Paez, Diana, Einstein, Andrew J., Cerci, Rodrigo, Vitola, Joao V., Hinterleitner, Gerd, Lu, Yao, Morozova, Olga, Xu, Zhuoran, Cohen, Yosef, Choi, Andrew, Lopez-Mattei, Juan, Parwani, Purvi, Nasery, Mohammad Nawaz, Goda, Artan, Shirka, Ervina, Benlabgaa, Rabie, Bouyoucef, Salah, Medjahedi, Abdelkader, Nailli, Qais, Agolti, Mariela, Aguero, Roberto Nicolas, Alak, Maria del Carmen, Alberguina, Lucia Graciela, Arroñada, Guillermo, Astesiano, Andrea, Astesiano, Alfredo, Norton, Carolina Bas, Benteo, Pablo, Blanco, Juan, Bonelli, Juan Manuel, Bustos, Jose Javier, Cabrejas, Raul, Cachero, Jorge, Campisi, Roxana, Canderoli, Alejandro, Carames, Silvia, Carrascosa, Patrícia, Castro, Ricardo, Cendoya, Oscar, Cognigni, Luciano Martin, Collaud, Carlos, Cortes, Claudia, Courtis, Javier, Cragnolino, Daniel, Daicz, Mariana, De La Vega, Alejandro, De Maria, Silvia Teresa, Del Riego, Horacio, Dettori, Fernando, Deviggiano, Alejandro, Dragonetti, Laura, Embon, Mario, Enriquez, Ruben Emilio, Ensinas, Jorge, Faccio, Fernando, Facello, Adolfo, Garofalo, Diego, Geronazzo, Ricardo, Gonza, Natalia, Gutierrez, Lucas, Guzzo, Miguel Angel, Hasbani, Victor, Huerin, Melina, Jäger, Victor, Lewkowicz, Julio Manuel, López De Munaín, Maria Nieves A., Lotti, Jose Maria, Marquez, Alejandra, Masoli, Osvaldo, Masoli, Osvaldo Horacio, Mastrovito, Edgardo, Mayoraz, Matias, Melado, Graciela Eva, Mele, Anibal, Merani, Maria Fernanda, Meretta, Alejandro Horacio, Molteni, Susana, Montecinos, Marcos, Noguera, Eduardo, Novoa, Carlos, Sueldo, Claudio Pereyra, Ascani, Sebastian Perez, Pollono, Pablo, Pujol, Maria Paula, Radzinschi, Alejandro, Raimondi, Gustavo, Redruello, Marcela, Rodríguez, Marina, Rodríguez, Matías, Romero, Romina Lorena, Acuña, Arturo Romero, Rovaletti, Federico, San Miguel, Lucas, Solari, Lucrecia, Strada, Bruno, Traverso, Sonia, Traverzo, Sonia Simona, Espeche, Maria del Huerto Velazquez, Weihmuller, Juan Sebastian, Wolcan, Juan, Zeffiro, Susana, Sakanyan, Mari, Beuzeville, Scott, Boktor, Raef, Butler, Patrick, Calcott, Jennifer, Carr, Loretta, Chan, Virgil, Chao, Charles, Chong, Woon, Dobson, Mark, Downie, D'Arne, Dwivedi, Girish, Elison, Barry, Engela, Jean, Francis, Roslyn, Gaikwad, Anand, Basavaraj, Ashok Gangasandra, Goodwin, Bruce, Greenough, Robert, Hamilton-Craig, Christian, Hsieh, Victar, Joshi, Subodh, Lederer, Karin, Lee, Kenneth, Lee, Joseph, Magnussen, John, Mai, Nghi, Mander, Gordon, Murton, Fiona, Nandurkar, Dee, Neill, Johanne, O'Rourke, Edward, O'Sullivan, Patricia, Pandos, George, Pathmaraj, Kunthi, Pitman, Alexander, Poulter, Rohan, Premaratne, Manuja, Prior, David, Ridley, Lloyd, Rutherford, Natalie, Salehi, Hamid, Saunders, Connor, Scarlett, Luke, Seneviratne, Sujith, Shetty, Deepa, Shrestha, Ganesh, Shulman, Jonathan, Solanki, Vijay, Stanton, Tony, Stuart, Murch, Stubbs, Michael, Swainson, Ian, Taubman, Kim, Taylor, Andrew, Thomas, Paul, Unger, Steven, Upton, Anthony, Vamadevan, Shankar, Van Gaal, William, Verjans, Johan, Voutnis, Demetrius, Wayne, Victor, Wilson, Peter, Wong, David, Wong, Kirby, Younger, John, Feuchtner, Gudrun, Mirzaei, Siroos, Weiss, Konrad, Maroz-Vadalazhskaya, Natallia, Gheysens, Olivier, Homans, Filip, Moreno-Reyes, Rodrigo, Pasquet, Agnès, Roelants, Veronique, Van De Heyning, Caroline M., Ríos, Raúl Araujo, Soldat-Stankovic, Valentina, Stankovic, Sinisa, Albernaz Siqueira, Maria Helena, Almeida, Augusto, Alves Togni, Paulo Henrique, Andrade, Jose Henrique, Andrade, Luciana, Anselmi, Carlos, Araújo, Roberta, Azevedo, Guilherme, Bezerra, Sabbrina, Biancardi, Rodrigo, Grossman, Gabriel Blacher, Brandão, Simone, Pianta, Diego Bromfman, Carreira, Lara, Castro, Bruno, Chang, Tien, Cunali, Fernando, Cury, Roberto, Dantas, Roberto, de Amorim Fernandes, Fernando, De Lorenzo, Andrea, De Macedo Filho, Robson, Erthal, Fernanda, Fernandes, Fabio, Fernandes, Juliano, De Souza, Thiago Ferreira, Alves, Wilson Furlan, Ghini, Bruno, Goncalves, Luiz, Gottlieb, Ilan, Hadlich, Marcelo, Kameoka, Vinícius, Lima, Ronaldo, Lima, Adna, Lopes, Rafael Willain, Machado e Silva, Ricardo, Magalhães, Tiago, Silva, Fábio Martins, Mastrocola, Luiz Eduardo, Medeiros, Fábio, Meneghetti, José Claudio, Naue, Vania, Naves, Danilo, Nolasco, Roberto, Nomura, Cesar, Oliveira, Joao Bruno, Paixao, Eduardo, De Carvalho, Filipe Penna, Pinto, Ibraim, Possetti, Priscila, Quinta, Mayra, Nogueira Ramos, Rodrigo Rizzo, Rocha, Ricardo, Rodrigues, Alfredo, Rodrigues, Carlos, Romantini, Leila, Sanches, Adelina, Santana, Sara, Sara da Silva, Leonardo, Schvartzman, Paulo, Matushita, Cristina Sebastião, Senra, Tiago, Shiozaki, Afonso, Menezes de Siqueira, Maria Eduarda, Siqueira, Cristiano, Smanio, Paola, Soares, Carlos Eduardo, Junior, José Soares, Bittencourt, Marcio Sommer, Spiro, Bernardo, Mesquita, Cláudio Tinoco, Torreao, Jorge, Torres, Rafael, Uellendahl, Marly, Monte, Guilherme Urpia, Veríssimo, Otávia, Cabeda, Estevan Vieira, Pedras, Felipe Villela, Waltrick, Roberto, Zapparoli, Marcello, Naseer, Hamid, Garcheva-Tsacheva, Marina, Kostadinova, Irena, Theng, Youdaline, Abikhzer, Gad, Barette, Rene, Chow, Benjamin, Dabreo, Dominique, Friedrich, Matthias, Garg, Ria, Hafez, Mohammed Nassoh, Johnson, Chris, Kiess, Marla, Leipsic, Jonathon, Leung, Eugene, Miller, Robert, Oikonomou, Anastasia, Probst, Stephan, Roifman, Idan, Small, Gary, Tandon, Vikas, Trivedi, Adwait, White, James, Zukotynski, Katherine, Canessa, Jose, Muñoz, Gabriel Castro, Concha, Carmen, Hidalgo, Pablo, Lovera, Cesar, Massardo, Teresa, Vargas, Luis Salazar, Abad, Pedro, Arturo, Harold, Ayala, Sandra, Benitez, Luis, Cadena, Alberto, Caicedo, Carlos, Moncayo, Antonio Calderón, Gomez, Sharon, Gutierrez Villamil, Claudia T., Jaimes, Claudia, Londoño, Juan, Londoño Blair, Juan Luis, Pabon, Luz, Pineda, Mauricio, Rojas, Juan Carlos, Ruiz, Diego, Escobar, Manuel Valencia, Vasquez, Andres, Vergel, Damiana, Zuluaga, Alejandro, Gamboa, Isabel Berrocal, Castro, Gabriel, González, Ulises, Baric, Ana, Batinic, Tonci, Franceschi, Maja, Paar, Maja Hrabak, Jukic, Mladen, Medakovic, Petar, Persic, Viktor, Prpic, Marina, Punda, Ante, Batista, Juan Felipe, Gómez Lauchy, Juan Manuel, Gutierrez, Yamile Marcos, Menéndez, Rayner, Peix, Amalia, Rochela, Luis, Panagidis, Christoforos, Petrou, Ioannis, Engelmann, Vaclav, Kaminek, Milan, Kincl, Vladimír, Lang, Otto, Simanek, Milan, Abdulla, Jawdat, Bøttcher, Morten, Christensen, Mette, Gormsen, Lars Christian, Hasbak, Philip, Hess, Søren, Holdgaard, Paw, Johansen, Allan, Kyhl, Kasper, Norgaard, Bjarne Linde, Øvrehus, Kristian Altern, Rønnow Sand, Niels Peter, Steffensen, Rolf, Thomassen, Anders, Zerahn, Bo, Perez, Alfredo, Escorza Velez, Giovanni Alejandro, Velez, Mayra Sanchez, Abdel Aziz, Islam Shawky, Abougabal, Mahasen, Ahmed, Taghreed, Allam, Adel, Asfour, Ahmed, Hassan, Mona, Hassan, Alia, Ibrahim, Ahmed, Kaffas, Sameh, Kandeel, Ahmed, Ali, Mohamed Mandour, Mansy, Ahmad, Maurice, Hany, Nabil, Sherif, Shaaban, Mahmoud, Flores, Ana Camila, Poksi, Anne, Knuuti, Juhani, Kokkonen, Velipekka, Larikka, Martti, Uusitalo, Valtteri, Bailly, Matthieu, Burg, Samuel, Deux, Jean-François, Habouzit, Vincent, Hyafil, Fabien, Lairez, Olivier, Proffit, Franck, Regaieg, Hamza, Sarda-Mantel, Laure, Tacher, Vania, Schneider, Roman P., Ayetey, Harold, Angelidis, George, Archontaki, Aikaterini, Chatziioannou, Sofia, Datseris, Ioannis, Fragkaki, Christina, Georgoulias, Panagiotis, Koukouraki, Sophia, Koutelou, Maria, Kyrozi, Eleni, Repasos, Evangelos, Stavrou, Petros, Valsamaki, Pipitsa, Gonzalez, Carla, Gutierrez, Goleat, Maldonado, Alejandro, Buga, Klara, Garai, Ildiko, Maurovich-Horvat, Pál, Schmidt, Erzsébet, Szilveszter, Balint, Várady, Edit, Banthia, Nilesh, Bhagat, Jinendra Kumar, Bhargava, Rishi, Bhat, Vivek, Choudhury, Partha, Chowdekar, Vijay Sai, Irodi, Aparna, Jain, Shashank, Joseph, Elizabeth, Kumar, Sukriti, Girijanandan Mahapatra, Prof Dr, Mitra, Deepanjan, Mittal, Bhagwant Rai, Ozair, Ahmad, Patel, Chetan, Patel, Tapan, Patel, Ravi, Patel, Shivani, Saxena, Sudhir, Sengupta, Shantanu, Singh, Santosh, Singh, Bhanupriya, Sood, Ashwani, Verma, Atul, Affandi, Erwin, Alam, Padma Savenadia, Edison, Edison, Gunawan, Gani, Hapkido, Habusari, Hidayat, Basuki, Huda, Aulia, Mukti, Anggoro Praja, Prawiro, Djoko, Soeriadi, Erwin Affandi, Syawaluddin, Hilman, Albadr, Amjed, Assadi, Majid, Emami, Farshad, Houshmand, Golnaz, Maleki, Majid, Rostami, Maryam Tajik, Zakavi, Seyed Rasoul, Zaid, Eed Abu, Agranovich, Svetlana, Arnson, Yoav, Bar-Shalom, Rachel, Frenkel, Alex, Knafo, Galit, Lugassi, Rachel, Maor Moalem, Israel Shlomo, Mor, Maya, Muskal, Noam, Ranser, Sara, Shalev, Aryeh, Albano, Domenico, Alongi, Pierpaolo, Arnone, Gaspare, Bagatin, Elisa, Baldari, Sergio, Bauckneht, Matteo, Bertelli, Paolo, Bianco, Francesco, Bonfiglioli, Rachele, Boni, Roberto, Bruno, Andrea, Bruno, Isabella, Busnardo, Elena, Califaretti, Elena, Camoni, Luca, Carnevale, Aldo, Casoni, Roberta, Cavallo, Armando Ugo, Cavenaghi, Giorgio, Chierichetti, Franca, Chiocchi, Marcello, Cittanti, Corrado, Colletta, Mauro, Conti, Umberto, Cossu, Alberto, Cuocolo, Alberto, Cuzzocrea, Marco, De Rimini, Maria Luisa, De Vincentis, Giuseppe, Del Giudice, Eleonora, Del Torto, Alberico, Della Tommasina, Veronica, Durmo, Rexhep, Erba, Paola Anna, Evangelista, Laura, Faletti, Riccardo, Faragasso, Evelina, Farsad, Mohsen, Ferro, Paola, Florimonte, Luigia, Frantellizzi, Viviana, Fringuelli, Fabio Massimo, Gatti, Marco, Gaudiano, Angela, Gimelli, Alessia, Giubbini, Raffaele, Giuffrida, Francesca, Ialuna, Salvatore, Laudicella, Riccardo, Leccisotti, Lucia, Leva, Lucia, Liga, Riccardo, Liguori, Carlo, Longo, Giampiero, Maffione, Margherita, Mancini, Maria Elisabetta, Marcassa, Claudio, Milan, Elisa, Nardi, Barbara, Pacella, Sara, Pepe, Giovanna, Pontone, Gianluca, Pulizzi, Sabina, Quartuccio, Natale, Rampin, Lucia, Ricci, Fabrizio, Rossini, Pierluigi, Rubini, Giuseppe, Russo, Vincenzo, Sacchetti, Gian Mauro, Sambuceti, Gianmario, Scarano, Massimo, Sciagrà, Roberto, Sperandio, Massimiliano, Stefanelli, Antonella, Ventroni, Guido, Zoboli, Stefania, Baugh, Dainia, Chambers, Duane, Madu, Ernest, Nunura, Felix, Asano, Hiroshi, Chimura, Chimura Misato, Fujimoto, Shinichiro, Fujisue, Koichiro, Fukunaga, Tomohisa, Fukushima, Yoshimitsu, Fukuyama, Kae, Hashimoto, Jun, Ichikawa, Yasutaka, Iguchi, Nobuo, Imai, Masamichi, Inaki, Anri, Ishimura, Hayato, Isobe, Satoshi, Kadokami, Toshiaki, Kato, Takao, Kumita, Shinichiro, Maruno, Hirotaka, Mataki, Hiroyuki, Miyagawa, Masao, Morimoto, Ryota, Moroi, Masao, Nagamachi, Shigeki, Nakajima, Kenichi, Nakata, Tomoaki, Nakazato, Ryo, Nanasato, Mamoru, Naya, Masanao, Norikane, Takashi, Ohta, Yasutoshi, Okayama, Satoshi, Okizaki, Atsutaka, Otomi, Yoichi, Otsuka, Hideki, Saito, Masaki, Sakata, Sakata Yasushi, Sarai, Masayoshi, Sato, Daisuke, Shiraishi, Shinya, Suwa, Yoshinobu, Takanami, Kentaro, Takehana, Kazuya, Taki, Junichi, Tamaki, Nagara, Taniguchi, Yasuyo, Teragawa, Hiroki, Tomizawa, Nobuo, Tsujita, Kenichi, Umeji, Kyoko, Wakabayashi, Yasushi, Yamada, Shinichiro, Yamazaki, Shinya, Yoneyama, Tatsuya, Rawashdeh, Mohammad, Batyrkhanov, Daultai, Makhdomi, Khalid, Ombati, Kevin, Alkandari, Faridah, Garashi, Masoud, Coie, Tchoyoson Lim, Rajvong, Sonexay, Kalinin, Artem, Kalnina, Marika, Haidar, Mohamad, Komiagiene, Renata, Kviecinskiene, Giedre, Mataciunas, Mindaugas, Vajauskas, Donatas, Picard, Christian, Karim, Noor Khairiah A., Reichmuth, Luise, Samuel, Anthony, Allarakha, Mohammad Aaftaab, Naojee, Ambedhkar Shantaram, Alexanderson-Rosas, Erick, Barragan, Erika, González-Montecinos, Alejandro Becerril, Cabada, Manuel, Rodriguez, Daniel Calderon, Carvajal-Juarez, Isabel, Cortés, Violeta, Cortés, Filiberto, De La Peña, Erasmo, Gama-Moreno, Manlio, González, Luis, Ramírez, Nelsy Gonzalez, Jiménez-Santos, Moisés, Matos, Luis, Monroy, Edgar, Morelos, Martha, Ornelas, Mario, Ortga Ramirez, Jose Alberto, Preciado-Anaya, Andrés, Preciado-Gutiérrez, Óscar Ulises, Barragan, Adriana Puente, Rosales Uvera, Sandra Graciela, Sandoval, Sigelinda, Tomas, Miguel Santaularia, Sierra-Galan, Lilia M., Siu, Silvia, Vallejo, Enrique, Valles, Mario, Faraggi, Marc, Sereegotov, Erdenechimeg, Ilic, Srdja, Ben-Rais, Nozha, Alaoui, Nadia Ismaili, Taleb, Sara, Pa Myo, Khin Pa, Thu, Phyo Si, Ghimire, Ram Kumar, Rajbanshi, Bijoy, Barneveld, Peter, Glaudemans, Andor, Habets, Jesse, Koopmans, Klaas Pieter, Manders, Jeroen, Pool, Stefan, Scholte, Arthur, Scholtens, Asbjørn, Slart, Riemer, Thimister, Paul, Van Asperen, Erik-Jan, Veltman, Niels, Verschure, Derk, Wagenaar, Nils, Edmond, John, Ellis, Chris, Johnson, Kerryanne, Keenan, Ross, Kueh, Shaw Hua (Anthony), Occleshaw, Christopher, Sasse, Alexander, To, Andrew, Van Pelt, Niels, Young, Calum, Cuadra, Teresa, Roque Vanegas, Hector Bladimir, Soli, Idrissa Adamou, Issoufou, Djibrillou Moussa, Ayodele, Tolulope, Madu, Chibuzo, Onimode, Yetunde, Efros-Monsen, Elen, Forsdahl, Signe Helene, Hildre Dimmen, Jenni-Mari, Jørgensen, Arve, Krohn, Isabel, Løvhaugen, Pål, Bråten, Anders Tjellaug, Al Dhuhli, Humoud, Al Kindi, Faiza, Al-Bulushi, Naeema, Jawa, Zabah, Tag, Naima, Afzal, Muhammad Shehzad, Fatima, Shazia, Younis, Muhammad Numair, Riaz, Musab, Saadullah, Mohammad, Herrera, Yariela, Lenturut-Katal, Dora, Vázquez, Manuel Castillo, Ortellado, José, Akhter, Afroza, Cao, Dianbo, Cheung, Stephen, Dai, Xu, Gong, Lianggeng, Han, Dan, Hou, Yang, Li, Caiying, Li, Tao, Li, Dong, Li, Sijin, Liu, Jinkang, Liu, Hui, Ng, Ming Yen, Sun, Kai, Tang, Gongshun, Wang, Jian, Wang, Ximing, Wang, Zhao-Qian, Wang, Yining, Wang, Yifan, Wu, Jiang, Wu, Zhifang, Xia, Liming, Xiao, Jiangxi, Xu, Lei, Yang, Youyou, Yin, Wu, Yu, Jianqun, Yuan, Li, Zhang, Tong, Zhang, Longjiang, Zhang, Yong-Gao, Zhang, Xiaoli, Zhu, Li, Alfaro, Ana, Abrihan, Paz, Barroso, Asela, Cruz, Eric, Gomez, Marie Rhiamar, Magboo, Vincent Peter, Medina, John Michael, Obaldo, Jerry, Pastrana, Davidson, Pawhay, Christian Michael, Quinon, Alvin, Tang, Jeanelle Margareth, Tecson, Bettina, Uson, Kristine Joy, Uy, Mila, Kostkiewicz, Magdalena, Kunikowska, Jolanta, Bettencourt, Nuno, Cantinho, Guilhermina, Ferreira, Antonio, Syed, Ghulam, Arnous, Samer, Atyani, Said, Byrne, Angela, Gleeson, Tadhg, Kerins, David, Meehan, Conor, Murphy, David, Murphy, Mark, Murray, John, O'Brien, Julie, Bang, Ji-In, Bom, Henry, Cho, Sang-Geon, Hong, Chae Moon, Jang, Su Jin, Jeong, Yong Hyu, Kang, Won Jun, Kim, Ji-Young, Lee, Jaetae, Namgung, Chang Kyeong, So, Young, Won, Kyoung Sook, Majstorov, Venjamin, Vavlukis, Marija, Salobir, Barbara Gužic, Štalc, Monika, Benedek, Theodora, Benedek, Imre, Mititelu, Raluca, Stan, Claudiu Adrian, Ansheles, Alexey, Dariy, Olga, Drozdova, Olga, Gagarina, Nina, Gulyaev, Vsevolod Milyevich, Itskovich, Irina, Karalkin, Anatoly, Kokov, Alexander, Migunova, Ekaterina, Pospelov, Viktor, Ryzhkova, Daria, Saifullina, Guzaliya, Sazonova, Svetlana, Sergienko, Vladimir, Shurupova, Irina, Trifonova, Tatjana, Ussov, Wladimir Yurievich, Vakhromeeva, Margarita, Valiullina, Nailya, Zavadovsky, Konstantin, Zhuravlev, Kirill, Okarvi, Subhani, Saranovic, Dragana Sobic, Keng, Felix, Jason See, Jia Hao, Sekar, Ramkumar, Yew, Min Sen, Vondrak, Andrej, Bejai, Shereen, Bennie, George, Bester, Ria, Engelbrecht, Gerrit, Evbuomwan, Osayande, Gongxeka, Harlem, Vuuren, Magritha Jv, Kaplan, Mitchell, Khushica, Purbhoo, Lakhi, Hoosen, Louw, Lizette, Malan, Nico, Milos, Katarina, Modiselle, Moshe, More, Stuart, Naidoo, Mathava, Scholtz, Leonie, Vangu, Mboyo, Aguadé-Bruix, Santiago, Blanco, Isabel, Cabrera, Antonio, Camarero, Alicia, Casáns-Tormo, Irene, Cuellar-Calabria, Hug, Flotats, Albert, Fuentes Cañamero, Maria Eugenia, García, María Elia, Jimenez-Heffernan, Amelia, Leta, Rubén, Diaz, Javier Lopez, Lumbreras, Luis, Marquez-Cabeza, Juan Javier, Martin, Francisco, Martinez de Alegria, Anxo, Medina, Francisco, Canal, Maria Pedrera, Peiro, Virginia, Pubul-Nuñez, Virginia, Rayo Madrid, Juan Ignacio, Rey, Cristina Rodríguez, Perez, Ricardo Ruano, Ruiz, Joaquín, Hernández, Gertrudis Sabatel, Sevilla, Ana, Zeidán, Nahla, Nanayakkara, Damayanthi, Udugama, Chandraguptha, Simonsson, Magnus, Alkadhi, Hatem, Buechel, Ronny Ralf, Burger, Peter, Ceriani, Luca, De Boeck, Bart, Gräni, Christoph, Juillet de Saint Lager Lucas, Alix, Kamani, Christel H., Kawel-Boehm, Nadine, Manka, Robert, Prior, John O., Rominger, Axel, Vallée, Jean-Paul, Khiewvan, Benjapa, Premprabha, Teerapon, Thientunyakit, Tanyaluck, Sellem, Ali, Kir, Kemal Metin, Sayman, Haluk, Sebikali, Mugisha Julius, Muyinda, Zerida, Kmetyuk, Yaroslav, Korol, Pavlo, Mykhalchenko, Olena, Pliatsek, Volodymyr, Satyr, Maryna, Albalooshi, Batool, Ahmed Hassan, Mohamed Ismail, Anderson, Jill, Bedi, Punit, Biggans, Thomas, Bularga, Anda, Bull, Russell, Burgul, Rajesh, Carpenter, John-Paul, Coles, Duncan, Cusack, David, Deshpande, Aparna, Dougan, John, Fairbairn, Timothy, Farrugia, Alexia, Gopalan, Deepa, Gummow, Alistair, Ramkumar, Prasad Guntur, Hamilton, Mark, Harbinson, Mark, Hartley, Thomas, Hudson, Benjamin, Joshi, Nikhil, Kay, Michael, Kelion, Andrew, Khokhar, Azhar, Kitt, Jamie, Lee, Ken, Low, Chen, Mak, Sze Mun, Marousa, Ntouskou, Martin, Jon, Mcalindon, Elisa, Menezes, Leon, Morgan-Hughes, Gareth, Moss, Alastair, Murray, Anthony, Nicol, Edward, Patel, Dilip, Peebles, Charles, Pugliese, Francesca, Luis Rodrigues, Jonathan Carl, Rofe, Christopher, Sabharwal, Nikant, Schofield, Rebecca, Semple, Thomas, Sharma, Naveen, Strouhal, Peter, Subedi, Deepak, Topping, William, Tweed, Katharine, Weir-Mccall, Jonathan, Abbara, Suhny, Abbasi, Taimur, Abbott, Brian, Abohashem, Shady, Abramson, Sandra, Al-Abboud, Tarek, Al-Mallah, Mouaz, Almousalli, Omar, Ananthasubramaniam, Karthikeyan, Kumar, Mohan Ashok, Askew, Jeffrey, Attanasio, Lea, Balmer-Swain, Mallory, Bayer, Richard R., Bernheim, Adam, Bhatti, Sabha, Bieging, Erik, Blankstein, Ron, Bloom, Stephen, Blue, Sean, Bluemke, David, Borges, Andressa, Branch, Kelley, Bravo, Paco, Brothers, Jessica, Budoff, Matthew, Bullock-Palmer, Renée, Burandt, Angela, Burke, Floyd W., Bush, Kelvin, Candela, Candace, Capasso, Elizabeth, Cavalcante, Joao, Chang, Donald, Chatterjee, Saurav, Chatzizisis, Yiannis, Cheezum, Michael, Chen, Tiffany, Chen, Jennifer, Chen, Marcus, Clarcq, James, Cordero, Ayreen, Crim, Matthew, Danciu, Sorin, Decter, Bruce, Dhruva, Nimish, Doherty, Neil, Doukky, Rami, Dunbar, Anjori, Duvall, William, Edwards, Rachael, Esquitin, Kerry, Farah, Husam, Fentanes, Emilio, Ferencik, Maros, Fisher, Daniel, Fitzpatrick, Daniel, Foster, Cameron, Fuisz, Tony, Gannon, Michael, Gastner, Lori, Gerson, Myron, Ghoshhajra, Brian, Goldberg, Alan, Goldner, Brian, Gonzalez, Jorge, Gore, Rosco, Gracia-López, Sandra, Hage, Fadi, Haider, Agha, Haider, Sofia, Hamirani, Yasmin, Hassen, Karen, Hatfield, Mallory, Hawkins, Carolyn, Hawthorne, Katie, Heath, Nicholas, Hendel, Robert, Hernandez, Phillip, Hill, Gregory, Horgan, Stephen, Huffman, Jeff, Hurwitz, Lynne, Iskandrian, Ami, Janardhanan, Rajesh, Jellis, Christine, Jerome, Scott, Kalra, Dinesh, Kaviratne, Summanther, Kay, Fernando, Kelly, Faith, Khalique, Omar, Kinkhabwala, Mona, Iii, George Kinzfogl, Kircher, Jacqueline, Kirkbride, Rachael, Kontos, Michael, Kottam, Anupama, Krepp, Joseph, Layer, Jay, Lee, Steven H., Leppo, Jeffrey, Lesser, John, Leung, Steve, Lewin, Howard, Litmanovich, Diana, Liu, Yiyan, Magurany, Kathleen, Markowitz, Jeremy, Marn, Amanda, Matis, Stephen E., Mckenna, Michael, Mcrae, Tony, Mendoza, Fernando, Merhige, Michael, Min, David, Moffitt, Chanan, Moncher, Karen, Moore, Warren, Morayati, Shamil, Morris, Michael, Mossa-Basha, Mahmud, Mrsic, Zorana, Murthy, Venkatesh, Nagpal, Prashant, Napier, Kyle, Nelson, Katarina, Nijjar, Prabhjot, Osman, Medhat, Passen, Edward, Patel, Amit, Patil, Pravin, Paul, Ryan, Phillips, Lawrence, Polsani, Venkateshwar, Poludasu, Rajaram, Pomerantz, Brian, Porter, Thomas, Prentice, Ryan, Pursnani, Amit, Rabbat, Mark, Ramamurti, Suresh, Rich, Florence, Luna, Hiram Rivera, Robinson, Austin, Robles, Kim, Rodríguez, Cesar, Rorie, Mark, Rumberger, John, Russell, Raymond, Sabra, Philip, Sadler, Diego, Schemmer, Mary, Schoepf, U. 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Kenichi, Umeji, Kyoko, Wakabayashi, Yasushi, Yamada, Shinichiro, Yamazaki, Shinya, Yoneyama, Tatsuya, Rawashdeh, Mohammad, Batyrkhanov, Daultai, Makhdomi, Khalid, Ombati, Kevin, Alkandari, Faridah, Garashi, Masoud, Coie, Tchoyoson Lim, Rajvong, Sonexay, Kalinin, Artem, Kalnina, Marika, Haidar, Mohamad, Komiagiene, Renata, Kviecinskiene, Giedre, Mataciunas, Mindaugas, Vajauskas, Donatas, Picard, Christian, Karim, Noor Khairiah A., Reichmuth, Luise, Samuel, Anthony, Allarakha, Mohammad Aaftaab, Naojee, Ambedhkar Shantaram, Alexanderson-Rosas, Erick, Barragan, Erika, González-Montecinos, Alejandro Becerril, Cabada, Manuel, Rodriguez, Daniel Calderon, Carvajal-Juarez, Isabel, Cortés, Violeta, Cortés, Filiberto, De La Peña, Erasmo, Gama-Moreno, Manlio, González, Luis, Ramírez, Nelsy Gonzalez, Jiménez-Santos, Moisés, Matos, Luis, Monroy, Edgar, Morelos, Martha, Ornelas, Mario, Ortga Ramirez, Jose Alberto, Preciado-Anaya, Andrés, Preciado-Gutiérrez, Óscar Ulises, Barragan, Adriana Puente, Rosales Uvera, Sandra Graciela, Sandoval, Sigelinda, Tomas, Miguel Santaularia, Sierra-Galan, Lilia M., Siu, Silvia, Vallejo, Enrique, Valles, Mario, Faraggi, Marc, Sereegotov, Erdenechimeg, Ilic, Srdja, Ben-Rais, Nozha, Alaoui, Nadia Ismaili, Taleb, Sara, Pa Myo, Khin Pa, Thu, Phyo Si, Ghimire, Ram Kumar, Rajbanshi, Bijoy, Barneveld, Peter, Glaudemans, Andor, Habets, Jesse, Koopmans, Klaas Pieter, Manders, Jeroen, Pool, Stefan, Scholte, Arthur, Scholtens, Asbjørn, Slart, Riemer, Thimister, Paul, Van Asperen, Erik-Jan, Veltman, Niels, Verschure, Derk, Wagenaar, Nils, Edmond, John, Ellis, Chris, Johnson, Kerryanne, Keenan, Ross, Kueh, Shaw Hua (Anthony), Occleshaw, Christopher, Sasse, Alexander, To, Andrew, Van Pelt, Niels, Young, Calum, Cuadra, Teresa, Roque Vanegas, Hector Bladimir, Soli, Idrissa Adamou, Issoufou, Djibrillou Moussa, Ayodele, Tolulope, Madu, Chibuzo, Onimode, Yetunde, Efros-Monsen, Elen, Forsdahl, Signe Helene, Hildre Dimmen, Jenni-Mari, Jørgensen, Arve, Krohn, Isabel, Løvhaugen, Pål, Bråten, Anders Tjellaug, Al Dhuhli, Humoud, Al Kindi, Faiza, Al-Bulushi, Naeema, Jawa, Zabah, Tag, Naima, Afzal, Muhammad Shehzad, Fatima, Shazia, Younis, Muhammad Numair, Riaz, Musab, Saadullah, Mohammad, Herrera, Yariela, Lenturut-Katal, Dora, Vázquez, Manuel Castillo, Ortellado, José, Akhter, Afroza, Cao, Dianbo, Cheung, Stephen, Dai, Xu, Gong, Lianggeng, Han, Dan, Hou, Yang, Li, Caiying, Li, Tao, Li, Dong, Li, Sijin, Liu, Jinkang, Liu, Hui, Ng, Ming Yen, Sun, Kai, Tang, Gongshun, Wang, Jian, Wang, Ximing, Wang, Zhao-Qian, Wang, Yining, Wang, Yifan, Wu, Jiang, Wu, Zhifang, Xia, Liming, Xiao, Jiangxi, Xu, Lei, Yang, Youyou, Yin, Wu, Yu, Jianqun, Yuan, Li, Zhang, Tong, Zhang, Longjiang, Zhang, Yong-Gao, Zhang, Xiaoli, Zhu, Li, Alfaro, Ana, Abrihan, Paz, Barroso, Asela, Cruz, Eric, Gomez, Marie Rhiamar, Magboo, Vincent Peter, Medina, John Michael, Obaldo, Jerry, Pastrana, Davidson, Pawhay, Christian Michael, Quinon, Alvin, Tang, Jeanelle Margareth, Tecson, Bettina, Uson, Kristine Joy, Uy, Mila, Kostkiewicz, Magdalena, Kunikowska, Jolanta, Bettencourt, Nuno, Cantinho, Guilhermina, Ferreira, Antonio, Syed, Ghulam, Arnous, Samer, Atyani, Said, Byrne, Angela, Gleeson, Tadhg, Kerins, David, Meehan, Conor, Murphy, David, Murphy, Mark, Murray, John, O'Brien, Julie, Bang, Ji-In, Bom, Henry, Cho, Sang-Geon, Hong, Chae Moon, Jang, Su Jin, Jeong, Yong Hyu, Kang, Won Jun, Kim, Ji-Young, Lee, Jaetae, Namgung, Chang Kyeong, So, Young, Won, Kyoung Sook, Majstorov, Venjamin, Vavlukis, Marija, Salobir, Barbara Gužic, Štalc, Monika, Benedek, Theodora, Benedek, Imre, Mititelu, Raluca, Stan, Claudiu Adrian, Ansheles, Alexey, Dariy, Olga, Drozdova, Olga, Gagarina, Nina, Gulyaev, Vsevolod Milyevich, Itskovich, Irina, Karalkin, Anatoly, Kokov, Alexander, Migunova, Ekaterina, Pospelov, Viktor, Ryzhkova, Daria, Saifullina, Guzaliya, Sazonova, Svetlana, Sergienko, Vladimir, Shurupova, Irina, Trifonova, Tatjana, Ussov, Wladimir Yurievich, Vakhromeeva, Margarita, Valiullina, Nailya, Zavadovsky, Konstantin, Zhuravlev, Kirill, Okarvi, Subhani, Saranovic, Dragana Sobic, Keng, Felix, Jason See, Jia Hao, Sekar, Ramkumar, Yew, Min Sen, Vondrak, Andrej, Bejai, Shereen, Bennie, George, Bester, Ria, Engelbrecht, Gerrit, Evbuomwan, Osayande, Gongxeka, Harlem, Vuuren, Magritha Jv, Kaplan, Mitchell, Khushica, Purbhoo, Lakhi, Hoosen, Louw, Lizette, Malan, Nico, Milos, Katarina, Modiselle, Moshe, More, Stuart, Naidoo, Mathava, Scholtz, Leonie, Vangu, Mboyo, Aguadé-Bruix, Santiago, Blanco, Isabel, Cabrera, Antonio, Camarero, Alicia, Casáns-Tormo, Irene, Cuellar-Calabria, Hug, Flotats, Albert, Fuentes Cañamero, Maria Eugenia, García, María Elia, Jimenez-Heffernan, Amelia, Leta, Rubén, Diaz, Javier Lopez, Lumbreras, Luis, Marquez-Cabeza, Juan Javier, Martin, Francisco, Martinez de Alegria, Anxo, Medina, Francisco, Canal, Maria Pedrera, Peiro, Virginia, Pubul-Nuñez, Virginia, Rayo Madrid, Juan Ignacio, Rey, Cristina Rodríguez, Perez, Ricardo Ruano, Ruiz, Joaquín, Hernández, Gertrudis Sabatel, Sevilla, Ana, Zeidán, Nahla, Nanayakkara, Damayanthi, Udugama, Chandraguptha, Simonsson, Magnus, Alkadhi, Hatem, Buechel, Ronny Ralf, Burger, Peter, Ceriani, Luca, De Boeck, Bart, Gräni, Christoph, Juillet de Saint Lager Lucas, Alix, Kamani, Christel H., Kawel-Boehm, Nadine, Manka, Robert, Prior, John O., Rominger, Axel, Vallée, Jean-Paul, Khiewvan, Benjapa, Premprabha, Teerapon, Thientunyakit, Tanyaluck, Sellem, Ali, Kir, Kemal Metin, Sayman, Haluk, Sebikali, Mugisha Julius, Muyinda, Zerida, Kmetyuk, Yaroslav, Korol, Pavlo, Mykhalchenko, Olena, Pliatsek, Volodymyr, Satyr, Maryna, Albalooshi, Batool, Ahmed Hassan, Mohamed Ismail, Anderson, Jill, Bedi, Punit, Biggans, Thomas, Bularga, Anda, Bull, Russell, Burgul, Rajesh, Carpenter, John-Paul, Coles, Duncan, Cusack, David, Deshpande, Aparna, Dougan, John, Fairbairn, Timothy, Farrugia, Alexia, Gopalan, Deepa, Gummow, Alistair, Ramkumar, Prasad Guntur, Hamilton, Mark, Harbinson, Mark, Hartley, Thomas, Hudson, Benjamin, Joshi, Nikhil, Kay, Michael, Kelion, Andrew, Khokhar, Azhar, Kitt, Jamie, Lee, Ken, Low, Chen, Mak, Sze Mun, Marousa, Ntouskou, Martin, Jon, Mcalindon, Elisa, Menezes, Leon, Morgan-Hughes, Gareth, Moss, Alastair, Murray, Anthony, Nicol, Edward, Patel, Dilip, Peebles, Charles, Pugliese, Francesca, Luis Rodrigues, Jonathan Carl, Rofe, Christopher, Sabharwal, Nikant, Schofield, Rebecca, Semple, Thomas, Sharma, Naveen, Strouhal, Peter, Subedi, Deepak, Topping, William, Tweed, Katharine, Weir-Mccall, Jonathan, Abbara, Suhny, Abbasi, Taimur, Abbott, Brian, Abohashem, Shady, Abramson, Sandra, Al-Abboud, Tarek, Al-Mallah, Mouaz, Almousalli, Omar, Ananthasubramaniam, Karthikeyan, Kumar, Mohan Ashok, Askew, Jeffrey, Attanasio, Lea, Balmer-Swain, Mallory, Bayer, Richard R., Bernheim, Adam, Bhatti, Sabha, Bieging, Erik, Blankstein, Ron, Bloom, Stephen, Blue, Sean, Bluemke, David, Borges, Andressa, Branch, Kelley, Bravo, Paco, Brothers, Jessica, Budoff, Matthew, Bullock-Palmer, 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- Abstract
Background: The coronavirus disease-2019 (COVID-19) pandemic significantly affected management of cardiovascular disease around the world. The effect of the pandemic on volume of cardiovascular diagnostic procedures is not known. Objectives: This study sought to evaluate the effects of the early phase of the COVID-19 pandemic on cardiovascular diagnostic procedures and safety practices in Asia. Methods: The International Atomic Energy Agency conducted a worldwide survey to assess changes in cardiovascular procedure volume and safety practices caused by COVID-19. Testing volumes were reported for March 2020 and April 2020 and were compared to those from March 2019. Data from 180 centers across 33 Asian countries were grouped into 4 subregions for comparison. Results: Procedure volumes decreased by 47% from March 2019 to March 2020, showing recovery from March 2020 to April 2020 in Eastern Asia, particularly in China. The majority of centers cancelled outpatient activities and increased time per study. Practice changes included implementing physical distancing and restricting visitors. Although COVID testing was not commonly performed, it was conducted in one-third of facilities in Eastern Asia. The most severe reductions in procedure volumes were observed in lower-income countries, where volumes decreased 81% from March 2019 to April 2020. Conclusions: The COVID-19 pandemic in Asia caused significant reductions in cardiovascular diagnostic procedures, particularly in low-income countries. Further studies on effects of COVID-19 on cardiovascular outcomes and changes in care delivery are warranted.
- Published
- 2021
38. Indirect imaging of cardiac-specific transgene expression using a bidirectional two-step transcriptional amplification strategy
- Author
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Chen, I Y, Gheysens, O, Ray, S, Wang, Q, Padmanabhan, P, Paulmurugan, R, Loening, A M, Rodriguez-Porcel, M, Willmann, J K, Sheikh, A Y, Nielsen, C H, Hoyt, G, Contag, C H, Robbins, R C, Biswal, S, Wu, J C, and Gambhir, S S
- Published
- 2010
- Full Text
- View/download PDF
39. Joint EANM/SNMMI/ANZSNM practice guidelines/procedure standards on recommended use of [18F]FDG PET/CT imaging during immunomodulatory treatments in patients with solid tumors version 1.0.
- Author
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Lopci, E., Hicks, R. J., Dimitrakopoulou-Strauss, A., Dercle, L., Iravani, A., Seban, R. D., Sachpekidis, C., Humbert, O., Gheysens, O., Glaudemans, A. W. J. M., Weber, W., Wahl, R. L., Scott, A. M., Pandit-Taskar, N., and Aide, N.
- Subjects
NUCLEAR medicine ,IMMUNOTHERAPY ,ONCOLOGY ,INFLAMMATION ,COMPANION diagnostics - Abstract
Purpose: The goal of this guideline/procedure standard is to assist nuclear medicine physicians, other nuclear medicine professionals, oncologists or other medical specialists for recommended use of [
18 F]FDG PET/CT in oncological patients undergoing immunotherapy, with special focus on response assessment in solid tumors. Methods: In a cooperative effort between the EANM, the SNMMI and the ANZSNM, clinical indications, recommended imaging procedures and reporting standards have been agreed upon and summarized in this joint guideline/procedure standard. Conclusions: The field of immuno-oncology is rapidly evolving, and this guideline/procedure standard should not be seen as definitive, but rather as a guidance document standardizing the use and interpretation of [18 F]FDG PET/CT during immunotherapy. Local variations to this guideline should be taken into consideration. Preamble: The European Association of Nuclear Medicine (EANM) is a professional non-profit medical association founded in 1985 to facilitate worldwide communication among individuals pursuing clinical and academic excellence in nuclear medicine. The Society of Nuclear Medicine and Molecular Imaging (SNMMI) is an international scientific and professional organization founded in 1954 to promote science, technology and practical application of nuclear medicine. The Australian and New Zealand Society of Nuclear Medicine (ANZSNM), founded in 1969, represents the major professional society fostering the technical and professional development of nuclear medicine practice across Australia and New Zealand. It promotes excellence in the nuclear medicine profession through education, research and a commitment to the highest professional standards. EANM, SNMMI and ANZSNM members are physicians, technologists, physicists and scientists specialized in the research and clinical practice of nuclear medicine. All three societies will periodically put forth new standards/guidelines for nuclear medicine practice to help advance the science of nuclear medicine and improve service to patients. Existing standards/guidelines will be reviewed for revision or renewal, as appropriate, on their fifth anniversary or sooner, if indicated. Each standard/guideline, representing a policy statement by the EANM/SNMMI/ANZSNM, has undergone a thorough consensus process, entailing extensive review. These societies recognize that the safe and effective use of diagnostic nuclear medicine imaging requires particular training and skills, as described in each document. These standards/guidelines are educational tools designed to assist practitioners in providing appropriate and effective nuclear medicine care for patients. These guidelines are consensus documents based on current knowledge. They are not intended to be inflexible rules or requirements of practice, nor should they be used to establish a legal standard of care. For these reasons and those set forth below, the EANM, SNMMI and ANZSNM caution against the use of these standards/guidelines in litigation in which the clinical decisions of a practitioner are called into question. The ultimate judgment regarding the propriety of any specific procedure or course of action must be made by medical professionals considering the unique circumstances of each case. Thus, there is no implication that an action differing from what is laid out in the guidelines/procedure standards, standing alone, is below standard of care. To the contrary, a conscientious practitioner may responsibly adopt a course of action different from that set forth in the standards/guidelines when, in the reasonable judgment of the practitioner, such course of action is indicated by the condition of the patient, limitations of available resources or advances in knowledge or technology subsequent to publication of the guidelines/procedure standards. The practice of medicine involves not only the science, but also the art of dealing with the prevention, diagnosis, alleviation and treatment of disease. The variety and complexity of human conditions make it impossible for general guidelines to consistently allow for an accurate diagnosis to be reached or a particular treatment response to be predicted. Therefore, it should be recognized that adherence to these standards/ guidelines will not ensure a successful outcome. All that should be expected is that practitioners follow a reasonable course of action, based on their level of training, current knowledge, clinical practice guidelines, available resources and the needs/context of the patient being treated. The sole purpose of these guidelines is to assist practitioners in achieving this objective. The present guideline/procedure standard was developed collaboratively by the EANM, the SNMMI and the ANZSNM, with the support of international experts in the field. They summarize also the views of the Oncology and Theranostics and the Inflammation and Infection Committees of the EANM, as well as the procedure standards committee of the SNMMI, and reflect recommendations for which the EANM and SNMMI cannot be held responsible. The recommendations should be taken into the context of good practice of nuclear medicine and do not substitute for national and international legal or regulatory provisions. [ABSTRACT FROM AUTHOR]- Published
- 2022
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40. In-depth characterization of the tumor microenvironment in central nervous system lymphoma reveals implications for immune-checkpoint therapy
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Marcelis, L, Antoranz, A, Delsupehe, A, Biesemans, P, Ferreiro, J, Debackere, K, Vandenberghe, P, Verhoef, G, Gheysens, O, Cattoretti, G, Bosisio, F, Sagaert, X, Dierickx, D, Tousseyn, T, Marcelis, Lukas, Antoranz, Asier, Delsupehe, Anne-Marie, Biesemans, Pauline, Ferreiro, Julio Finalet, Debackere, Koen, Vandenberghe, Peter, Verhoef, Gregor, Gheysens, Olivier, Cattoretti, Giorgio, Bosisio, Francesca Maria, Sagaert, Xavier, Dierickx, Daan, Tousseyn, Thomas, Marcelis, L, Antoranz, A, Delsupehe, A, Biesemans, P, Ferreiro, J, Debackere, K, Vandenberghe, P, Verhoef, G, Gheysens, O, Cattoretti, G, Bosisio, F, Sagaert, X, Dierickx, D, Tousseyn, T, Marcelis, Lukas, Antoranz, Asier, Delsupehe, Anne-Marie, Biesemans, Pauline, Ferreiro, Julio Finalet, Debackere, Koen, Vandenberghe, Peter, Verhoef, Gregor, Gheysens, Olivier, Cattoretti, Giorgio, Bosisio, Francesca Maria, Sagaert, Xavier, Dierickx, Daan, and Tousseyn, Thomas
- Abstract
Primary central nervous system lymphoma (PCNSL) is a rare type of non-Hodgkin lymphoma with an aggressive clinical course. To investigate the potential of immune-checkpoint therapy, we retrospectively studied the tumor microenvironment (TME) using high-plex immunohistochemistry in 22 PCNSL and compared to 7 secondary CNS lymphomas (SCNSL) and 7 "other" CNSL lymphomas with the presence of the Epstein-Barr virus and/or compromised immunity. The TME in PCNSL was predominantly composed of CD8+ cytotoxic T cells and CD163+ phagocytes. Despite molecular differences between PCNSL and SCNSL, the cellular composition and the functional spectrum of cytotoxic T cells were similar. But cytotoxic T cell activation was significantly influenced by pre-biopsy corticosteroids intake, tumor expression of PD-L1 and the presence of EBV. The presence of low numbers of CD8+ T cells and geographic-type necrosis each predicted inferior outcome in PCNSL. Both M1-like (CD68 + CD163low) and M2-like (CD68 + CD163high) phagocytes were identified, and an increased ratio of M1-like/M2-like phagocytes was associated with a better survival. PD-L1 was expressed in lymphoma cells in 28% of cases, while PD1 was expressed in only 0.4% of all CD8+ T cells. TIM-3, a marker for T cell exhaustion, was significantly more expressed in CD8posPD-1pos T cells compared to CD8posPD-1neg T cells, and a similar increased expression was observed in M2-like pro-tumoral phagocytes. In conclusion, the clinical impact of TME composition supports the use of immune-checkpoint therapies in PCNSL. Based on observed differences in immune-checkpoint expression, combinations that boost cytotoxic T cell activation (by blocking TIM-3 or TGFBR1) prior to the administration of PD-L1 inhibition could be of interest.
- Published
- 2020
41. Metabolic-structural concordance in paraneoplastic limbic encephalitis
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Goffin, K. E., Ooms, D., Ahmad, R., Demaerel, P., Van Paesschen, W., Van Laere, K., Vansteenkiste, J., Deroose, C. M., and Gheysens, O.
- Published
- 2016
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42. Diagnostic value of [18F]FDG-PET/CT in polymyalgia rheumatica: a systematic review and meta-analysis
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van der Geest, K. S. M., primary, Treglia, G., additional, Glaudemans, A. W. J. M., additional, Brouwer, E., additional, Jamar, F., additional, Slart, R. H. J. A., additional, and Gheysens, O., additional
- Published
- 2020
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43. The value of 18F-FDG PET/CT for the diagnosis of device-related infections in patients with a left ventricular assist device: a systematic review and meta-analysis
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ten Hove, D., primary, Treglia, G., additional, Slart, R. H. J. A., additional, Damman, K., additional, Wouthuyzen-Bakker, M., additional, Postma, D. F., additional, Gheysens, O., additional, Borra, R. J. H., additional, Mecozzi, G., additional, van Geel, P. P., additional, Sinha, B., additional, and Glaudemans, A. W. J. M., additional
- Published
- 2020
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44. The relation between cardiac 123I-mIBG scintigraphy and functional response 1 year after CRT implantation
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Verschure, D O, primary, Poel, E, additional, De Vincentis, G, additional, Frantellizzi, V, additional, Nakajima, K, additional, Gheysens, O, additional, de Groot, J R, additional, and Verberne, H J, additional
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- 2020
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45. P975 Echocardiography and nuclear medicine imaging techniques are insufficient for scar detection in patients referred for cardiac resynchronization therapy
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Kjellstad Larsen, C, primary, Galli, E, additional, Duchenne, J, additional, Aalen, J M, additional, Stokke, C, additional, Degtiarova, G, additional, Fjeld, J G, additional, Gheysens, O, additional, Saberniak, J, additional, Kongsgaard, E, additional, Penicka, M, additional, Voigt, J-U, additional, Donal, E, additional, Smiseth, O A, additional, and Hopp, E, additional
- Published
- 2020
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46. A joint procedural position statement on imaging in cardiac sarcoidosis
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Slart, R. H. J. A., Glaudemans, A. W. J. M., Lancellotti, P., Hyafil, F., Blankstein, R., Schwartz, R. G., Jaber, W. A., Russell, R., Gimelli, A., Rouzet, F., Hacker, M., Gheysens, O., Plein, S., Miller, E. J., Dorbala, S., Donal, E., Sciagra, R., Bucerius, J., Verberne, H. J., Lindner, O., Ubleis, C., Agostini, D., Signore, A., Edvardsen, T., Neglia, D., Beanlands, R. S., Di Carli, M., Chareonthaitawee, P., Dilsizian, V., Soman, P., Habib, G., Delgado, V., Cardim, N., Cosyns, B., Flachskampf, F., Gerber, B., Haugaa, K., Lombardi, M., Masci, P. G., Nuclear Medicine, ACS - Amsterdam Cardiovascular Sciences, Radiology and Nuclear Medicine, Unité de Recherche sur les Maladies Infectieuses Tropicales Emergentes (URMITE), Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS), Groupe Interdisciplinaire de Génoprotéomique Appliquée (GIGA-Research), Université de Liège, Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de cardiologie et maladies vasculaires [Rennes] = Cardiac, Thoracic, and Vascular Surgery [Rennes], CHU Pontchaillou [Rennes], CIC-IT Rennes, Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre d'Investigation Clinique [Rennes] (CIC), Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Jonchère, Laurent, INSB-INSB-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, INSB-INSB-Centre National de la Recherche Scientifique (CNRS), RS: CARIM - R3.11 - Imaging, MUMC+: DA BV Medisch Specialisten Nucleaire Geneesk (9), Beeldvorming, Biomedical Photonic Imaging, Clinical sciences, Cardio-vascular diseases, Cardiology, Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Vascular Ageing Programme (VAP), Translational Immunology Groningen (TRIGR), Cardiovascular Centre (CVC), and Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE)
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Male ,positron emission tomography ,diagnosis ,[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging ,Biopsy ,diagnostic ,Speckle tracking echocardiography ,030204 cardiovascular system & hematology ,Myocardial Perfusion Imaging/standards ,medical ,Multimodal Imaging ,cardiac sarcoidosis ,030218 nuclear medicine & medical imaging ,0302 clinical medicine ,X ray computed ,cardiac imaging techniques ,cardiology ,cardiomyopathies ,europe ,female ,humans ,magnetic resonance imaging ,male ,multimodal imaging ,myocardial perfusion imaging ,nuclear medicine ,positron emission tomography computed tomography ,radionuclide imaging ,sarcoidosis ,societies, medical ,united states ,practice guidelines as topic ,Positron Emission Tomography Computed Tomography ,MAGNETIC-RESONANCE ,Image Processing, Computer-Assisted ,Medicine ,echocardiography ,F-18-FDG PET ,Positron Emission Tomography Computed Tomography/standards ,ComputingMilieux_MISCELLANEOUS ,Societies, Medical ,medicine.diagnostic_test ,HYPERTROPHIC CARDIOMYOPATHY ,LATE GADOLINIUM ENHANCEMENT ,Hypertrophic cardiomyopathy ,Myocardial Perfusion Imaging ,CORTICOSTEROID-THERAPY ,imaging ,Sarcoidosis/diagnostic imaging ,General Medicine ,F 18 fdg pet ,Prognosis ,Magnetic Resonance Imaging ,3. Good health ,Europe ,Positron emission tomography ,Practice Guidelines as Topic ,Cardiology ,Nuclear Medicine/standards ,[SDV.IB]Life Sciences [q-bio]/Bioengineering ,Female ,Radiology ,Sarcoidosis ,STRAIN ECHOCARDIOGRAPHY ,Cardiology and Cardiovascular Medicine ,Cardiomyopathies ,Cardiology/standards ,Position statement ,Diagnostic Imaging ,medicine.medical_specialty ,SPECKLE-TRACKING ECHOCARDIOGRAPHY ,Systemic sarcoidosis ,SYSTEMIC SARCOIDOSIS ,Cardiac sarcoidosis ,fluorodeoxyglucose ,Imaging Sarcoidosis Myocardium ,Myocardial perfusion imaging ,03 medical and health sciences ,Cardiomyopathies/diagnostic imaging ,Radionuclide Imaging/standards ,societies ,POSITRON-EMISSION-TOMOGRAPHY ,[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,Fluorodeoxyglucose F18 ,Internal medicine ,Medical imaging ,cardiac MRI ,Late gadolinium enhancement ,Humans ,Radiology, Nuclear Medicine and imaging ,Radionuclide Imaging ,[SDV.IB] Life Sciences [q-bio]/Bioengineering ,Multimodal Imaging/standards ,business.industry ,Magnetic Resonance Imaging/standards ,Reproducibility of Results ,LOW-CARBOHYDRATE-DIET ,Magnetic resonance imaging ,medicine.disease ,n/a OA procedure ,United States ,Cardiac Imaging Techniques/standards ,Cardiac Imaging Techniques ,MYOCARDIAL FDG UPTAKE ,inflammation ,Positron-Emission Tomography ,Position paper ,Nuclear Medicine ,business ,Nuclear medicine ,Tomography, X-Ray Computed - Abstract
International audience; This joint position paper illustrates the role and the correct use of echocardiography, radionuclide imaging with 18F-fluorodeoxyglucose positron emission tomography, radionuclide myocardial perfusion imaging and cardiovascular magnetic resonance imaging for the evaluation and management of patients with known or suspected cardiac sarcoidosis. This position paper will aid in standardizing imaging for cardiac sarcoidosis and may facilitate clinical trials and pooling of multi-centre data on cardiac sarcoidosis. Proposed flow charts for the work up and management of cardiac sarcoidosis are included.
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- 2017
47. Consensus document for the diagnosis of prosthetic joint infections: a joint paper by the EANM, EBJIS, and ESR (with ESCMID endorsement)
- Author
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Signore, A., Sconfienza, L.M., Borens, O., Glaudemans, AWJM, Cassar-Pullicino, V., Trampuz, A., Winkler, H., Gheysens, O., Vanhoenacker, FMHM, Petrosillo, N., and Jutte, P.C.
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Consensus ,Documentation ,Europe ,Evidence-Based Medicine ,Humans ,Nuclear Medicine ,Prosthesis-Related Infections/diagnosis ,Prosthesis-Related Infections/diagnostic imaging ,Societies, Scientific ,Guideline ,Imaging ,Infection diagnosis ,Prosthetic joint infection - Abstract
For the diagnosis of prosthetic joint infection, real evidence-based guidelines to aid clinicians in choosing the most accurate diagnostic strategy are lacking. To address this need, we performed a multidisciplinary systematic review of relevant nuclear medicine, radiological, orthopaedic, infectious, and microbiological literature to define the diagnostic accuracy of each diagnostic technique and to address and provide evidence-based answers on uniform statements for each topic that was found to be important to develop a commonly agreed upon diagnostic flowchart. The approach used to prepare this set of multidisciplinary guidelines was to define statements of interest and follow the procedure indicated by the Oxford Centre for Evidence-based Medicine (OCEBM).
- Published
- 2019
48. Consensus document for the diagnosis of peripheral bone infection in adults: a joint paper by the EANM, EBJIS, and ESR (with ESCMID endorsement)
- Author
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Glaudemans, AWJM, Jutte, P.C., Cataldo, M.A., Cassar-Pullicino, V., Gheysens, O., Borens, O., Trampuz, A., Wörtler, K., Petrosillo, N., Winkler, H., Signore, A., and Sconfienza, L.M.
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Adult ,Anti-Bacterial Agents/therapeutic use ,Consensus ,Documentation ,Europe ,Evidence-Based Medicine ,Humans ,Nuclear Medicine ,Osteitis/diagnostic imaging ,Osteitis/drug therapy ,Osteomyelitis/diagnostic imaging ,Osteomyelitis/drug therapy ,Societies, Scientific ,Diagnosis of infection ,Guideline ,Imaging ,Osteitis ,Osteomyelitis ,Peripheral bone infection - Abstract
In adults with a suspicion of peripheral bone infection, evidence-based guidelines in choosing the most accurate diagnostic strategy are lacking. To provide an evidence-based, multidisciplinary consensus document on the diagnostic management of adult patients with PBIs, we performed a systematic review of relevant infectious, microbiological, orthopedic, radiological, and nuclear medicine literature. Delegates from four European societies (European Bone and Joint Infection Society, European Society of Microbiology and Infectious Diseases, European Society or Radiology, and European Association of Nuclear Medicine) defined clinical questions to be addressed, thoroughly reviewed the literature pertinent to each of the questions, and thereby evaluated the diagnostic accuracy of each diagnostic technique. Inclusion of the papers per statement was based on a PICO (Population/problem - Intervention/indicator - Comparator - Outcome) question following the strategy reported by the Oxford Centre for Evidence-based Medicine. For each statement, the level of evidence was graded according to the 2011 review of the Oxford Centre for Evidence-based Medicine. All approved statements were addressed taking into consideration the available diagnostic procedures, patient acceptance, tolerability, complications, and costs in Europe. Finally, a commonly agreed-upon diagnostic flowchart was developed.
- Published
- 2019
49. Cardiac 123I-mIBG scintigraphy as a tool to optimize CRT patient selection
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Verschure, D. O., Poel, E., Frantellizzi, V., De Vincentis, G., Gheysens, O., de Groot, J. R., and H. J. Verberne.
- Published
- 2019
50. How does mechanical dyssynchrony affect the efficiency of the left ventricle?
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Nuyts, J., Unlu, SERKAN, Rega, F., Gheysens, O., Beela, A. S., Duchenne, J., Turco, A., Claus, P., Vunckx, K., and Voigt, J. -U.
- Published
- 2018
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