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27 results on '"Ghosn, Farah"'

9. Study of the pathophysiological mechanisms associated with the onset and course of neurodevelopmental disorders in preterm infants (the PeriSTRESS-PremTEA study): Rationale, objectives, design and sample description

Author

Navalón, Pablo, Merchan-Naranjo, Jéssica, Ghosn, Farah, Almansa, Belén, Chafer-Pericas, Consuelo, González-Peñas, Javier, Rodríguez-Toscano, Elisa, Zeballos, Susana, Arriaga, María, Castro Castro, Pedro, Blanco Bravo, Dorotea, Vento, Máximo, Pina-Camacho, Laura, and García-Blanco, Ana

Published
2021
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10. Attentional Patterns to Emotional Faces versus Scenes in Children with Autism Spectrum Disorders

Author

Ghosn, Farah, Perea, Manuel, Castelló, Javier, Vázquez, Miguel Ángel, Yáñez, Núria, Marcos, Inmaculada, Sahuquillo, Rosa, Vento, Máximo, and García-Blanco, Ana

Abstract

Previous research has shown attentional biases in children with autism spectrum disorders (ASD) when processing distressing information. This study examined these attentional patterns as a function of the type of stimulus (scenes and faces) and the stimulus valence (happy, sad, threatening, neutral) using a within-subject design. A dot-probe was applied to ASD (n = 24) and typically developing (TD) children (n = 24). Results showed no differences between the groups for happy and sad stimuli. Critically, ASD children showed an attentional bias toward threatening scenes but away from threatening faces. Thus, the type of stimuli modulated the direction of attentional biases to distressing information in ASD children. These results are discussed in the framework of current theories on cognitive and emotional processing in ASD.

Published
2019
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18. Study of the pathophysiological mechanisms associated with the onset and course of neurodevelopmental disorders in preterm infants (the PeriSTRESS-PremTEA study): Rationale, objectives, design and sample description

Author

Navalón, Pablo, Merchan-Naranjo, Jéssica, Ghosn, Farah, Almansa, Belén, Chafer-Pericas, Consuelo, González-Peñas, Javier, Rodríguez-Toscano, Elisa, Zeballos, Susana, Arriaga, María, Castro Castro, Pedro, Blanco Bravo, Dorotea, Vento, Máximo, Pina-Camacho, Laura, and García-Blanco, Ana

Abstract

There are few studies exploring the pathophysiological pathways that may condition differentially the emergence/course of neurodevelopmental disorders (ND) in very preterm and extremely preterm newborns (VPTN/EPTN). Furthermore, there are no established biological markers predictive of ND in this population. The aim of this study is four-fold: in two cohorts of VPTN/EPTN (i) to characterize the emergence/course of ND up to corrected-age 6 years, (ii) to identify those factors (from prenatal stages up to age 6 years) that explain the interindividual differences related to emergence/course of ND, (iii) to identify in the first hours/days of life a urinary metabolomic biomarker profile predictive of ND, and (iv) to determine longitudinally variations in DNA methylation patterns predictive of ND.

Published
2024
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19. DNA METHYLATION IN EXTREMELY PRETERM BIRTH: RELATIONSHIPS WITH NEURODEVELOPMENT, PSYCHIATRIC DISORDERS AND NEONATAL ACCELERATED AGING

Author

Gurriarán, Xaquín, primary, González-Peñas, Javier, additional, Caserini, Chiara, additional, Merchán-Naranjo, Jessica, additional, Santos, Laura, additional, Recio, Sandra, additional, Blanco, Dorotea, additional, Arriaga, Maria, additional, Zeballos, Susana, additional, Almansa, Belén, additional, Ghosn, Farah, additional, Lizarán-Villalba, Marta, additional, Arango, Celso, additional, García-Blanco, Ana, additional, and Pina-Camacho, Laura, additional

Published
2022
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21. Are Infants Born After an Episode of Suspected Preterm Labor at Risk of ADHD? A 30-Month Follow-up Study

Author

Navalon, Pablo, Ghosn, Farah, Ferrin, Maite, Almansa, Belen, Moreno-Gimenez, Alba, Campos-Berga, Laura, Sahuquillo-Leal, Rosa, Diago, Vicente, Vento, Maximo, and Garcia-Blanco, Ana

Subjects
preterm labor, preterm contractions, trauma, neurodevelopmental disorders, psychomotor development, tocolysis, ADHD, preterm birth, risk factors, pregnancy
Abstract

BACKGROUND: An episode of suspected preterm labor (SPL) may be by itself a pathological event that may alter the normal course of pregnancy and the offspring´s neurodevelopment. Certainly, the association between preterm birth and neurodevelopmental disorders can only be partially explained by the immaturity of the nervous system, as evidenced by the increased risk of ADHD in late-preterm infants without any neurological alteration. OBJECTIVE: This study examines if infants born after SPL may be at an increased risk of developing ADHD. Moreover, potential obstetric, perinatal, and psychosocial risk factors associated with ADHD in this population are examined. STUDY DESIGN: A prospective cohort study of 120 mother-infant pairs was conducted from the moment the mothers received a diagnosis of SPL until the infants' 30 months of life. Infants were divided according to the prematurity status: Full-term SPL-infants (n = 28, born at =37 weeks of gestation), late preterm SPL-infants (n = 56, born between 32 and

Published
2022

24. Trajectories of stress biomarkers and anxious-depressive symptoms from pregnancy to postpartum period in women with a trauma history

Author

Ghosn, Farah, primary, Almansa, Belén, additional, Moreno-Giménez, Alba, additional, Sahuquillo-Leal, Rosa, additional, Serrano-Lozano, Elena, additional, Hervás, David, additional, Diago, Vicente, additional, Cháfer-Pericás, Consuelo, additional, Vento, Máximo, additional, and García Blanco, Ana, additional

Published
2019
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27. Study of the pathophysiological mechanisms associated with the onset and course of neurodevelopmental disorders in preterm infants (the PeriSTRESS-PremTEA study): Rationale, objectives, design and sample description

Author

Navalón, Pablo, Merchan-Naranjo, Jéssica, Ghosn, Farah, Almansa, Belén, Chafer-Pericas, Consuelo, González-Peñas, Javier, Rodríguez-Toscano, Elisa, Zeballos, Susana, Arriaga, María, Castro Castro, Pedro, Blanco Bravo, Dorotea, Vento, Máximo, Pina-Camacho, Laura, and García-Blanco, Ana

Abstract

There are few studies exploring the pathophysiological pathways that may condition differentially the emergence/course of neurodevelopmental disorders (ND) in very preterm and extremely preterm newborns (VPTN/EPTN). Furthermore, there are no established biological markers predictive of ND in this population. The aim of this study is four-fold: in two cohorts of VPTN/EPTN (i) to characterize the emergence/course of ND up to corrected-age 6 years, (ii) to identify those factors (from prenatal stages up to age 6 years) that explain the interindividual differences related to emergence/course of ND, (iii) to identify in the first hours/days of life a urinary metabolomic biomarker profile predictive of ND, and (iv) to determine longitudinally variations in DNA methylation patterns predictive of ND.

Published
2023
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