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Your search keyword '"Giaquinto G"' showing total 11 results
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11 results on '"Giaquinto G"'

1. HIV-1 transmission through breast-milk

Author

De Martino, M., Tovo, P. A., Tozzi, A. E., Pezzotti, P., Galli, L., Liviadotti, S., Caselli, D., Marchisio, P., Giaquinto, G., Fioredda, F., Plebani, A., Gabiano, C., Zuccotti, V. G., Conte, A., Rizzi, M., Mazzoni, P. L., Ibba, P., Ferrarris, G., Benaglia, G., Stegagno, M., Masi, M., Dallacasa, P., Duse, Marzia, Rossi, G., Sciotto, A., Barbanera, M., De Mattia, D., Zaniboni, M., Bezzi, T., Campelli, A., Ciccimarra, F., Bassanetti, F., Consolini, R., Mazza, A., Tarallo, L., Altobelli, R., Castaldo, A., and Fundarò, C.

Subjects
medicine.medical_specialty, Multivariate analysis, business.industry, Immunology, Gestational age, Odds ratio, Logistic regression, medicine.disease, Confidence interval, Surgery, Infectious Diseases, Acquired immunodeficiency syndrome (AIDS), Immunology and Allergy, Medicine, Risk factor, business, Breast feeding, Demography
Abstract

Objectives To estimate the risk of HIV-1 transmission through breast-milk in children born to infected mothers, and to determine the relationship between duration of breast-feeding and risk. Design and methods The study population included 168 breast-fed and 793 bottle-fed children born to seropositive mothers. All subjects were enrolled and followed-up in the Italian Register for HIV Infection in Children; HIV sero-status was defined in all children. Multivariate analysis was performed using a logistic regression model. Independent variables included biological factors (duration of breast-feeding, gestational age, clinical condition of mother at delivery, mode of delivery, birth-weight and sex). Year of birth and age when HIV infection was diagnosed were also considered in the analysis attempting to control for possible selection biases. Results Breast-feeding increased the risk of HIV-1 transmission. The estimated adjusted odds ratio for 1 day of breast- versus bottle-feeding was 1.19 (95% confidence interval, 1.10-1.28). The infection odds ratio of breast- versus bottle-feeding increased with the natural logarithm of the duration of practice. Conclusions These results are the first to provide an appraisal of the additional risk of HIV-1 transmission associated with a seropositive mother breast-feeding her child. Biological significance of this route of transmission was supported by demonstration of a relationship between duration of breast-feeding and risk of HIV-1 transmission.

Published
1992

2. Long-term follow-up of HIV-seropositive children

Author

Italian Register for HIV Infection in Children Tovo, Martino, De, Gabiano, M, Galli, C, L, Partecipants:, Ferraris, Giaquinto, G, Casteili, C, Garetto, G, Vierucci, S, Marchisio, A, Zuccotti, P, Fundaro, Gv, Duse, C, Caselli, M, D, Maria, De, Plebani, A, Timpano, A, Lanari, C, Stegagno, M, Ruggeri, M, Gotta, M, Lipreri, G, Cellini, L, Osimani, M, Loriano, P, Benaglia, D, G, Mattia, De, Forni, D, Romano, Gl, Antonellini, A, Pintor, A, C, and Consolini, Rita

Published
1999

7. [Behavior of aldosterone and plasma renin activity after ACTH administration and insulin-induced hypoglycemia in patients with essential arterial hypertension].

Author

Tosti-Croce C, Graziosi S, Giaquinto G, Sparano F, and Sciarra F

Subjects
Adrenocorticotropic Hormone, Adult, Blood Glucose analysis, Humans, Insulin, Middle Aged, Aldosterone blood, Hydrocortisone blood, Hypertension blood, Renin blood
Abstract

The response of plasma aldosterone (PA) and plasma renin activity (PRA) to ACTH stimulation (0.25 mg Tetracosactide infusion/10 h) and to insulin-induced hypoglycemia (0.1 U/kg b.w.) has been studied in 34 essential hypertensive (EH) patients. Corticotrophin stimulation increases significantly PA, the percent increase being higher in normal PRA EH patients than in controls but comparable to controls in low PRA EH patients. PRA shows a slight and transient elevation. A significant increase in PA is observed also during the insulin test, but the percent increase is lower than that under ACTH stimulation. The possibility that aldosterone is involved, under severe and frequent stress, in the genesis of essential hypertension is discussed.

Published
1981

9. Diurnal 18-hydroxy-11-deoxycorticosterone pattern in human stable hypertension.

Author

Sparano F, Sciarra F, Sulon J, Giaquinto G, Mercuri MA, Odoardi A, Tosticroce C, Genard P, and Conti C

Subjects
Adolescent, Adult, Aldosterone blood, Cushing Syndrome complications, Humans, Hydrocortisone blood, Hypertension etiology, Kidney Diseases complications, Male, Nephrosclerosis complications, Renal Artery Obstruction complications, Renin blood, 18-Hydroxydesoxycorticosterone blood, Circadian Rhythm, Desoxycorticosterone analogs & derivatives, Hypertension blood
Abstract

Diurnal 18-hydroxy-11-deoxycorticosterone (18-OH-DOC) pattern was studied with RIA technique in 33 hypertensive patients in supine position and on normal sodium diet. The compound was evaluated every 2 h from 0800-2000 h. Simultaneously, plasma aldosterone and cortisol were measured. Abnormal 18-OH-DOC behavior was observed in only 2 out of 4 patients with Cushing's disease, while sporadic and slight elevations, synchronous with F, were seen in 5 out of 24 stable essential hypertensive patients [1 with normal plasma renin activity (PRA), 1 with low PRA, and 3 with high PRA]. 18-OH-DOC was normal in 2 cases of hypertension due to renal artery stenosis, in 1 patient with nephrosclerosis, and in 1 patient with horseshoe kidney. From these results, 18-OH-DOC does not seem to play an important pathogenetic role in stable essential hypertension, considering also the low mineralocorticoid activity of the compound.

Published
1978
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