Search

Your search keyword '"Gibelli, Maria Augusta Bento Cicaroni"' showing total 28 results
Start Over Author "Gibelli, Maria Augusta Bento Cicaroni"
28 results on '"Gibelli, Maria Augusta Bento Cicaroni"'

2. An autopsy study of the spectrum of severe COVID-19 in children: From SARS to different phenotypes of MIS-C

Author

Duarte-Neto, Amaro Nunes, Caldini, Elia Garcia, Gomes-Gouvêa, Michele Soares, Kanamura, Cristina Takami, de Almeida Monteiro, Renata Aparecida, Ferranti, Juliana Ferreira, Ventura, Andrea Maria Cordeiro, Regalio, Fabiane Aliotti, Fiorenzano, Daniela Matos, Gibelli, Maria Augusta Bento Cicaroni, Carvalho, Werther Brunow de, Leal, Gabriela Nunes, Pinho, João Renato Rebello, Delgado, Artur Figueiredo, Carneiro-Sampaio, Magda, Mauad, Thais, Ferraz da Silva, Luiz Fernando, Saldiva, Paulo Hilario Nascimento, and Dolhnikoff, Marisa

Published
2021
Full Text
View/download PDF

4. Three-Dimensional Ultrasound Evaluation of Lung Volume in Fetuses with Abdominal Wall Defect

Author

Nishie, Estela Naomi, primary, Osmundo Junior, Gilmar de Souza, additional, Mohamed, Samirah Hosney Mahmoud, additional, Tannuri, Ana Cristina Aoun, additional, Gibelli, Maria Augusta Bento Cicaroni, additional, Carvalho, Werther Brunow de, additional, Peres, Stela Verzinhasse, additional, Francisco, Rossana Pulcineli Vieira, additional, and Brizot, Maria de Lourdes, additional

Published
2023
Full Text
View/download PDF

5. Epidemiology of Neonatal Acute Respiratory Distress Syndrome: Prospective, Multicenter, International Cohort Study

Author

de Luca, Daniele, Tingay, David G., van Kaam, Anton H., van Tuijl, Minke, Courtney, Sherry E., Kneyber, Martin C. J., Tissieres, Pierre, Tridente, Ascanio, Rimensberger, Peter C., Pillow, J. Jane, Carnielli, Virgilio P., Nobile, Stefano, Shi, Yuan, Long, Chen, Barcos, Francisca, Hochberg, Amit, Crocker, Caroline E., Harrison, Allen, Perkins, Elizabeth, Mosca, Fabio, Mercadante, Domenica, Raimondi, Francesco, Capasso, Letizia, Kallio, Merja, Raschetti, Roberto, Cillis, Annagrazia, Soreze, Yohan, Black, Lachlan, Khan, Nash, Piastra, Marco, Conti, Giorgio, Danhaive, Olivier, Gibelli, Maria Augusta Bento Cicaroni, de Carvalho, Werther Brunow, Mulder, Estelle, Neonatology, ARD - Amsterdam Reproduction and Development, Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE), AP-HP - Hôpital Antoine Béclère [Clamart], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Hypertension pulmonaire : physiopathologie et innovation thérapeutique (HPPIT), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Murdoch Children's Research Institute (MCRI), University of Melbourne, Emma Children's Hospital, University of Amsterdam [Amsterdam] (UvA), University of Arkansas for Medical Sciences (UAMS), Beatrix Children's Hospital [Groningen, Pays-Bas], University Medical Center Groningen [Groningen] (UMCG), University of Groningen [Groningen], AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Manchester Metropolitan University (MMU), Hôpital Universitaire de Genève = University Hospitals of Geneva (HUG), The University of Western Australia (UWA), Telethon KIDS Institute, Dr. De Luca received funding from Chiesi Farmaceutici S.p.A., Abbvie, Vyaire, Getinge, Medtronic, Masimo, Natus, Airway Therapeutics, and Ophirex, Dr. Tingay is supported by the Victorian Government Infrastructure Support Program. Drs. Tingay and Pillow received support for article research from the National Health and Medical Research Council (NHMRC) (Australia) Fellowships GNT1053889 and GNT1077691, respectively.Dr. van Kaam’s intuition received funding from Vyaire, Mallinckrodt, and Chiesi Farmaceutici S.p.A. Dr. Kneyber received funding from the National Heart, Lung, and Blood Institute, ZonMW, Stichting Vrienden Beatrix Kinderziekenhuis, and University Medical Center Groningen. Dr. Tissieres received funding from Sanofi, Inotrem, and Sedana. Dr. Pillow’s institution received funding from the NHMRC Centre of Research Excellence, the NHMRC Senior Research Fellowship, Chiesi Farmaceutici S.p.A., and Draeger Medical, for the Neonatal ARDS Project Collaboration Group Collaborators : van Tuijl, Minke, Carnielli, Virgilio P., Nobile, Stefano, Shi, Yuan, Long, Chen, Barcos, Francisca, Hochberg, Amit, Crocker, Caroline E., Harrison, Allen, Perkins, Elizabeth, Mosca, Fabio, Mercadante, Domenica, Raimondi, Francesco, Capasso, Letizia, Kallio, Merja, Raschetti, Roberto, Cillis, Annagrazia, Soreze, Yohan, Black, Lachlan, Khan, Nash, Piastra, Marco, Conti, Giorgio, Danhaive, Olivier, Gibelli, Maria Augusta Bento Cicaroni, de Carvalho, Werther Brunow, and Mulder, Estelle

Subjects
Male, MESH: Respiratory Distress Syndrome, Critical Care and Intensive Care Medicine, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, Cohort Studies, MESH: Pregnancy, Extracorporeal Membrane Oxygenation, MESH: Extracorporeal Membrane Oxygenation, cohort study Fifteen academic neonatal ICUs acute respiratory distress syndrome, Pregnancy, MESH: Child, Humans, MESH: Respiratory Distress Syndrome, Newborn, observational, Prospective Studies, Multicenter, Child, MESH: Cohort Studies, Retrospective Studies, [SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/Pediatrics, Respiratory Distress Syndrome, Respiratory Distress Syndrome, Newborn, MESH: Humans, MESH: Infant, Newborn, respiratory failure, Infant, Newborn, MESH: Retrospective Studies, respiratory failure Prospective, acute respiratory distress syndrome, International Cohort Study, neonatal intensive care unit, MESH: Male, MESH: Prospective Studies, Prospective, Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA, international, Pediatrics, Perinatology and Child Health, outcome, Female, neonate, MESH: Female
Abstract

OBJECTIVES: Age-specific definitions for acute respiratory distress syndrome (ARDS) are available, including a specific definition for neonates (the "Montreux definition"). The epidemiology of neonatal ARDS is unknown. The objective of this study was to describe the epidemiology, clinical course, treatment, and outcomes of neonatal ARDS.DESIGN: Prospective, international, observational, cohort study.SETTING: Fifteen academic neonatal ICUs.PATIENTS: Consecutive sample of neonates of any gestational age admitted to participating sites who met the neonatal ARDS Montreux definition criteria.MEASUREMENTS AND MAIN RESULTS: Neonatal ARDS was classified as direct or indirect, infectious or noninfectious, and perinatal (≤ 72 hr after birth) or late in onset. Primary outcomes were: 1) survival at 30 days from diagnosis, 2) inhospital survival, and 3) extracorporeal membrane oxygenation (ECMO)-free survival at 30 days from diagnosis. Secondary outcomes included respiratory complications and common neonatal extrapulmonary morbidities. A total of 239 neonates met criteria for the diagnosis of neonatal ARDS. The median prevalence was 1.5% of neonatal ICU admissions with male/female ratio of 1.5. Respiratory treatments were similar across gestational ages. Direct neonatal ARDS (51.5% of neonates) was more common in term neonates and the perinatal period. Indirect neonatal ARDS was often triggered by an infection and was more common in preterm neonates. Thirty-day, inhospital, and 30-day ECMO-free survival were 83.3%, 76.2%, and 79.5%, respectively. Direct neonatal ARDS was associated with better survival outcomes than indirect neonatal ARDS. Direct and noninfectious neonatal ARDS were associated with the poorest respiratory outcomes at 36 and 40 weeks' postmenstrual age. Gestational age was not associated with any primary outcome on multivariate analyses.CONCLUSIONS: Prevalence and survival of neonatal ARDS are similar to those of pediatric ARDS. The neonatal ARDS subtypes used in the current definition may be associated with distinct clinical outcomes and a different distribution for term and preterm neonates.

Published
2022

7. MRSA outbreak in a Neonatal Intensive Care Unit in a developed country: importance of rapid detection of reservoirs and implementation of intervention measures

Author

Moura, Maria Luísa, primary, Rizek, Camila Fonseca, additional, Aguiar, Elisa, additional, Barros, Ana Natiele da Silva, additional, Costa, Sibeli, additional, Santos, Sania Alves dos, additional, Marchi, Ana Paula, additional, Gibelli, Maria Augusta Bento Cicaroni, additional, Tragante, Carla Regina, additional, Araújo, Maria Rita Elmor de, additional, Rossi, Flavia, additional, Guimaraes, Thais, additional, and Costa, Silvia Figueiredo, additional

Published
2022
Full Text
View/download PDF

8. Vertical transmission of SARS-CoV2 during pregnancy: A high-risk cohort

Author

Maeda, Mariane de Fátima Yukie, Brizot, Maria de Lourdes, Gibelli, Maria Augusta Bento Cicaroni, Ibidi, Silvia Maria, Carvalho, Werther Brunow de, Hoshida, Mara Sandra, Machado, Clarisse Martins, Sabino, Ester Cerdeira, Oliveira da Silva, Lea Campos de, Jaenisch, Thomas, Mendes-Correa, Maria Cássia Jacintho, Mayaud, Philippe, Francisco, Rossana Pulcinelli Vieira, and HC-FMUSP-Obstetric COVID19 Study Group

Abstract

OBJECTIVE: Identify the potential for and risk factors of SARS-CoV-2 vertical transmission. METHODS: Symptomatic pregnant women with COVID-19 diagnosis in whom PCR for SARS-CoV-2 was performed at delivery using maternal serum and at least one of the biological samples: cord blood (CB), amniotic fluid (AF), colostrum and/or oropharyngeal swab (OPS) of the neonate. The association of parameters with maternal, AF and/or CB positivity and the influence of SARS-CoV-2 positivity in AF and/or CB on neonatal outcomes were investigated. RESULTS: Overall 73.4% (80/109) were admitted in hospital due to COVID-19, 22.9% needed intensive care and there were four maternal deaths. Positive RT-PCR for SARS-CoV-2 was observed in 14.7% of maternal blood, 13.9% of AF, 6.7% of CB, 2.1% of colostrum and 3.7% of OPS samples. The interval between COVID-19 symptoms and delivery was inversely associated with SARS-CoV-2 positivity in the maternal blood (p = 0.002) and in the AF and/or CB (p = 0.049). Maternal viremia was associated with positivity for SARS-CoV-2 in AF and/or CB (p = 0.001). SARS-CoV-2 positivity in the compartments was not associated with neonatal outcomes. CONCLUSION: Vertical transmission is possible in pregnant women with COVID-19 and a shorter interval between maternal symptoms and delivery is an influencing factor.

Published
2021

9. Gastrointestinal manifestations are associated with severe pediatric COVID-19: A study in tertiary hospital

Author

de Paula, Camila Sanson Yoshino, primary, Palandri, Giovanna Gavros, additional, Fonseca, Taiane Siraisi, additional, Vendramini, Thaís Cristina Annibale, additional, Farhat, Sylvia Costa Lima, additional, Pereira, Maria Fernanda Badue, additional, Litvinov, Nadia, additional, Toma, Ricardo Katsuya, additional, de Sá, Fernanda Viveiros Moreira, additional, Rodrigues, Katharina Reichmann, additional, Schvartsman, Cláudio, additional, Forsait, Silvana, additional, Sakita, Neusa Keico, additional, Kanunfre, Kelly Aparecida, additional, Rocha, Mussya Cisotto, additional, dos Santos, Emilly Henrique, additional, Okay, Thelma Suely, additional, Pinho, João Renato Rebello, additional, de Carvalho, Werther Brunow, additional, Carneiro-Sampaio, Magda, additional, Almeida Silva, Clovis Artur, additional, Marques, Heloisa Helena de Sousa, additional, Eisencraft, Adriana Pasmanik, additional, Junior, Alfio Rossi, additional, Delgado, Artur Figueiredo, additional, Leal, Gabriela Nunes, additional, Framil, Juliana Valéria de Souza, additional, Gibelli, Maria Augusta Bento Cicaroni, additional, and Jorge, Patricia Palmeira Daenekas, additional

Published
2021
Full Text
View/download PDF

10. Use of lung ultrasound in neonates during the COVID-19 pandemic

Author

Matsuoka, Marcia Wang, Rocha, Silvia Maria Sucena da, Gibelli, Maria Augusta Bento Cicaroni, Nicolau, Carla Marques, Carvalho, Werther Brunow de, and Suzuki, Lisa

Subjects
Coronavirus, Coronavírus, Infecções por coronavírus/diagnóstico por imagem, Ultrassonografia, Pulmão/diagnóstico por imagem, Recém-nascido, Lung/diagnostic imaging, Coronavirus infections/diagnostic imaging, Ultrasonography, Infant, newborn
Abstract

In the current pandemic, caused by infection with severe acute respiratory syndrome coronavirus 2, ultrasound has played a fundamental role in patients who develop the resulting disease, designated coronavirus disease 2019 (COVID-19). In this study we present ultrasound images of the lungs of neonates with a suspected or confirmed diagnosis of COVID-19, distinguishing between the changes related to COVID-19 and those unrelated to the disease. Ultrasound examinations were performed by a pediatric sonographer. A total of 27 neonates were evaluated. Among those who presented no respiratory symptoms, some tested negative for COVID-19 and others tested positive. All of those who were pulmonary symptomatic, negative for COVID-19 presented transient tachypnea of the newborn and respiratory distress syndrome. Lung ultrasound images obtained in COVID-19-negative neonates showed, in some cases, a normal pattern (with A lines, few B lines, a thin, linear pleural line, and no pleural effusion), whereas in others showed coalescent B lines and areas of opacity. In two of the COVID-19-positive neonates, lung ultrasound examination showed several coalescent B lines, pleural thickening, and areas of opacity. Lung ultrasound in the neonatal period appears to be applicable within the context of the current pandemic, allowing efficient evaluation of COVID-19-related changes in neonates, as well as of pathologies inherent to the neonatal period. Resumo Na pandemia atual causada pelo SARS-CoV-19, a ultrassonografia (US) tem apresentado papel fundamental nos pacientes com COVID-19. Neste trabalho são mostradas imagens ultrassonográficas de recém-nascidos (RNs) suspeitos ou positivos para COVID-19 e alterações pulmonares não relacionadas a essa doença. As imagens ultrassonográficas foram obtidas por médico especialista em US pediátrica. Foram avaliados 27 RNs, sendo incluídos RNs assintomáticos da parte respiratória, COVID negativos e positivos, e RNs sintomáticos para a parte respiratória, COVID-negativos, observados na taquipneia transitória do recém-nascido ou na síndrome do desconforto respiratório. As imagens ultrassonográficas dos RNs negativos para COVID-19 mostraram tanto o padrão normal (presença de linhas A, poucas linhas B, linha pleural fina e linear, ausência de efusão pleural) quanto a presença de linhas B coalescentes e áreas de condensação pulmonar. Destaca-se a presença de dois RNs COVID-19 positivos apresentando múltiplas linhas B coalescentes, espessamento pleural e com áreas de condensação. Com este trabalho, os autores procuram demonstrar a aplicabilidade da US pulmonar dentro do contexto da pandemia da COVID-19, incluindo as doenças inerentes ao período neonatal.

Published
2020

12. Family Conferences in Prenatal Palliative Care

Author

Bernardes, Lisandra Stein, primary, Jesus, Roberta Carolina de Almeida, additional, Oliveira, Fernanda Figueiredo, additional, Benute, Glaucia Rosana Guerra, additional, Gibelli, Maria Augusta Bento Cicaroni, additional, Nascimento, Nathalia Bertolassi, additional, Bolibio, Renata, additional, Barbosa, Tercilia Virginia Aparecida, additional, Setubal, Maria Silvia Vellutini, additional, Gomes, Ana Lúcia, additional, Rocha, Luana Sarmento Neves, additional, Rosa, Gladys Ribeiro, additional, and Francisco, Rossana Pulcinelli, additional

Published
2020
Full Text
View/download PDF

13. Kidney impairment in fetal growth restriction: three‐dimensional evaluation of volume and vascularization

Author

Senra, Janaína Campos, primary, Yoshizaki, Carlos Tadashi, additional, Doro, Giovana Farina, additional, Ruano, Rodrigo, additional, Gibelli, Maria Augusta Bento Cicaroni, additional, Rodrigues, Agatha Sacramento, additional, Koch, Vera Hermina Kalika, additional, Krebs, Vera Lúcia Jornada, additional, Zugaib, Marcelo, additional, Francisco, Rossana Pulcineli Vieira, additional, and Bernardes, Lisandra Stein, additional

Published
2020
Full Text
View/download PDF

15. Severe clinical spectrum with high mortality in pediatric patients with COVID-19 and multisystem inflammatory syndrome

Author

Pereira, Maria Fernanda Badue, primary, Litvinov, Nadia, additional, Farhat, Sylvia Costa Lima, additional, Eisencraft, Adriana Pasmanik, additional, Gibelli, Maria Augusta Bento Cicaroni, additional, Carvalho, Werther Brunow de, additional, Fernandes, Vinicius Rodrigues, additional, Fink, Thais de Toledo, additional, Framil, Juliana Valéria de Souza, additional, Galleti, Karine Vusberg, additional, Fante, Alice Lima, additional, Fonseca, Maria Fernanda Mota, additional, Watanabe, Andreia, additional, Paula, Camila Sanson Yoshino de, additional, Palandri, Giovanna Gavros, additional, Leal, Gabriela Nunes, additional, Diniz, Maria de Fatima Rodrigues, additional, Pinho, João Renato Rebello, additional, Silva, Clovis Artur, additional, Marques, Heloisa Helena de Sousa, additional, Rossi Junior, Alfio, additional, Delgado, Artur Figueiredo, additional, Andrade, Anarella Penha Meirelles de, additional, Schvartsman, Claudio, additional, Sabino, Ester Cerdeira, additional, Rocha, Mussya Cisotto, additional, Kanunfre, Kelly Aparecida, additional, Okay, Thelma Suely, additional, Carneiro-Sampaio, Magda Maria Sales, additional, and Jorge, Patricia Palmeira Daenekas, additional

Published
2020
Full Text
View/download PDF

19. Assessment of newborn neuropsychomotor development born with exposure to SARS-CoV-2 in the perinatal period using the Bayley III scale at 6 months of age

Author

Orioli, Patricia Albertini, Johnston, Cintia, Del Bigio, Juliana Zoboli, Krebs, Vera Lucia Jornada, Pissolato, Mariana, Gibelli, Maria Augusta Bento Cicaroni, De Araujo, Orlei Ribeiro, Francisco, Rossana Pulcineli Vieira, and De Carvalho, Werther Brunow

Abstract

•The perinatal repercussions of the SARS-CoV-2 virus have not yet been elucidated.•Few reports in the literature indicate damage to the Neuro Psychomotor Development (NPMD) of children born during the COVID-19 pandemic, but its mechanisms are not clearly established.

Published
2024
Full Text
View/download PDF

20. Cuidados paliativos em medicina fetal

Author

Bolibio, Renata, primary, Jesus, Roberta Carolina De Almeida, additional, Oliveira, Fernanda Figueiredo de, additional, Gibelli, Maria Augusta Bento Cicaroni, additional, Benute, Glaucia Rosana Guerra, additional, Gomes, Ana Lucia, additional, Nascimento, Nathalia Bertolassi Oliveira do, additional, Barbosa, Tercilia Virginia Aparecida, additional, Zugaib, Marcelo, additional, Francisco, Rossana Pulcineli Vieira, additional, and Bernardes, Lisandra Stein, additional

Published
2018
Full Text
View/download PDF

21. Association of spontaneous labor onset with neonatal outcomes in pregnancies with fetal gastroschisis: A retrospective cohort analysis.

Author

Osmundo Junior, Gilmar de Souza, Mohamed, Samirah Hosney Mahmoud, Nishie, Estela Naomi, Tannuri, Ana Cristina Aoun, Gibelli, Maria Augusta Bento Cicaroni, Francisco, Rossana Pulcineli Vieira, and Brizot, Maria de Lourdes

Subjects
CHILDBIRTH, PREGNANCY complications, GASTROSCHISIS, COHORT analysis, ULTRASONIC imaging, DIAGNOSIS of neonatal diseases, INTESTINAL injuries, DELIVERY (Obstetrics), FETAL ultrasonic imaging, GESTATIONAL age, NEONATAL diseases, PREMATURE infants, INTESTINES, LABOR (Obstetrics), EVALUATION of medical care, PREGNANCY, PRENATAL care, RETROSPECTIVE studies
Abstract

Introduction: The present study aims to investigate the association of spontaneous labor onset with neonatal outcomes in pregnancies with fetal gastroschisis. The secondary goal was to evaluate the association between ultrasound markers and labor onset in pregnancies with fetal gastroschisis.Material and Methods: A retrospective analysis was performed for 207 pregnancies with fetal gastroschisis between 2005 and 2017. Patients were followed according to a strict protocol involving ultrasound scans and routine evaluations of fetal biophysical profile parameters and intra- and extra-abdominal bowel diameters. Labor, delivery and neonatal records were reviewed. The neonatal outcomes were complex gastroschisis, staged surgical closure of the abdominal defect, short bowel syndrome, time on mechanical ventilation, time to full enteral feeding and necrotizing enterocolitis.Results: Spontaneous labor onset was associated with complex gastroschisis (30.7% vs 6.8%, P = 0.002) and short bowel syndrome (13.2% vs none, P = 0.013) in cases with spontaneous preterm delivery compared with the indicated preterm deliveries. Spontaneous labor onset was associated with a longer time on mechanical ventilation for term and preterm newborns. Associations were not observed between ultrasound markers and spontaneous labor onset.Conclusions: Spontaneous labor onset in pregnancies with fetal gastroschisis was associated with adverse neonatal outcomes, particularly in those born preterm. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

22. Candida parapsilosiscandidaemia in a neonatal unit over 7 years: a case series study

Author

Miranda, Lourdes das Neves, primary, Rodrigues, Eliete C A, additional, Costa, Silvia F, additional, van der Heijden, Inneke Marie, additional, Dantas, Kátia C, additional, Lobo, Renata D, additional, Basso, Mariusa, additional, Varkulja, Gláucia F, additional, Krebs, Vera Lúcia Jornada, additional, Gibelli, Maria Augusta Bento Cicaroni, additional, Criado, Paulo R, additional, and Levin, Anna Sara, additional

Published
2012
Full Text
View/download PDF

25. Differences in children and adolescents with SARS-CoV-2 infection: a cohort study in a Brazilian tertiary referral hospital

Author

Marques, Heloisa Helena de Sousa, Pereira, Maria Fernanda Badue, Santos, Angélica Carreira dos, Fink, Thais Toledo, Paula, Camila Sanson Yoshino de, Litvinov, Nadia, Schvartsman, Claudio, Delgado, Artur Figueiredo, Gibelli, Maria Augusta Bento Cicaroni, Carvalho, Werther Brunow de, Odone, Vicente, Tannuri, Uenis, Carneiro-Sampaio, Magda, Grisi, Sandra, Duarte, Alberto José da Silva, Antonangelo, Leila, Francisco, Rossana Pucineli Vieira, Okay, Thelma Suely, Batisttella, Linamara Rizzo, Carvalho, Carlos Roberto Ribeiro de, Brentani, Alexandra Valéria Maria, Silva, Clovis Artur, and Group, HC-FMUSP Pediatric COVID Study

Abstract

To compare demographic/clinical/laboratory/treatments and outcomes among children and adolescents with laboratory-confirmed coronavirus disease 2019 (COVID-19).

Published
2021
Full Text
View/download PDF

26. Vertical transmission of SARS-CoV2 during pregnancy: A high-risk cohort.

Author

Maeda MFY, Brizot ML, Gibelli MABC, Ibidi SM, Carvalho WB, Hoshida MS, Machado CM, Sabino EC, Oliveira da Silva LC, Jaenisch T, Mendes-Correa MCJ, Mayaud P, and Francisco RPV

Subjects
Adult, Amniotic Fluid virology, Brazil epidemiology, COVID-19 mortality, COVID-19 virology, Colostrum virology, Female, Humans, Infant, Newborn, Male, Pregnancy, Pregnancy Complications, Infectious mortality, Prospective Studies, Young Adult, COVID-19 transmission, Infectious Disease Transmission, Vertical statistics & numerical data, Pregnancy Complications, Infectious virology, SARS-CoV-2 isolation & purification
Abstract

Objective: Identify the potential for and risk factors of SARS-CoV-2 vertical transmission., Methods: Symptomatic pregnant women with COVID-19 diagnosis in whom PCR for SARS-CoV-2 was performed at delivery using maternal serum and at least one of the biological samples: cord blood (CB), amniotic fluid (AF), colostrum and/or oropharyngeal swab (OPS) of the neonate. The association of parameters with maternal, AF and/or CB positivity and the influence of SARS-CoV-2 positivity in AF and/or CB on neonatal outcomes were investigated., Results: Overall 73.4% (80/109) were admitted in hospital due to COVID-19, 22.9% needed intensive care and there were four maternal deaths. Positive RT-PCR for SARS-CoV-2 was observed in 14.7% of maternal blood, 13.9% of AF, 6.7% of CB, 2.1% of colostrum and 3.7% of OPS samples. The interval between COVID-19 symptoms and delivery was inversely associated with SARS-CoV-2 positivity in the maternal blood (p = 0.002) and in the AF and/or CB (p = 0.049). Maternal viremia was associated with positivity for SARS-CoV-2 in AF and/or CB (p = 0.001). SARS-CoV-2 positivity in the compartments was not associated with neonatal outcomes., Conclusion: Vertical transmission is possible in pregnant women with COVID-19 and a shorter interval between maternal symptoms and delivery is an influencing factor., (© 2021 John Wiley & Sons Ltd.)

Published
2021
Full Text
View/download PDF

27. Expert recommendations for the care of newborns of mothers with COVID-19.

Author

Carvalho WB, Gibelli MABC, Krebs VLJ, Calil VMLT, and Johnston C

Subjects
COVID-19, Expert Testimony, Female, Humans, Infant, Newborn, Patient Isolation, Personal Protective Equipment, Practice Guidelines as Topic, Pregnancy, Risk Factors, SARS-CoV-2, Betacoronavirus, Coronavirus Infections prevention & control, Pandemics prevention & control, Pneumonia, Viral prevention & control, Pregnancy Complications, Infectious
Abstract

This article presents expert recommendations for assisting newborn children of mothers with suspected or diagnosed coronavirus disease 2019 (COVID-19). The consensus was developed by five experts with an average of 20 years of experience in neonatal intensive care working at a reference university hospital in Brazil for the care of pregnant women and newborns with suspected or confirmed COVID-19. Despite the lack of scientific evidence regarding the potential for viral transmission to their fetus in pregnant mothers diagnosed with or suspected of COVID-19, it is important to elaborate the lines of care by specialists from hospitals caring for suspected and confirmed COVID-19 cases to guide multidisciplinary teams and families diagnosed with the disease or involved in the care of pregnant women and newborns in this context. Multidisciplinary teams must be attentive to the signs and symptoms of COVID-19 so that decision-making is oriented and assertive for the management of the mother and newborn in both the hospital setting and at hospital discharge.

Published
2020
Full Text
View/download PDF

28. Candida parapsilosis candidaemia in a neonatal unit over 7 years: a case series study.

Author

Miranda Ld, Rodrigues EC, Costa SF, van der Heijden IM, Dantas KC, Lobo RD, Basso M, Varkulja GF, Krebs VL, Gibelli MA, Criado PR, and Levin AS

Abstract

Objective: To evaluate Candida parapsilosis candidaemia in a neonatal unit over 7 years., Design: Case series study., Setting: A 2000-bed tertiary-care university hospital at São Paulo, Brazil., Participants: Neonates hospitalised in a 63-bed neonatal unit., Primary and Secondary Outcome Measures: We evaluated the incidence of C parapsilosis fungemia in a neonatal unit from 2002 through 2008 and the main microbiological, clinical and epidemiological aspects of this disease in neonates. During the study period an outbreak occurred, an infection control programme was implemented, and isolates from blood and hand healthcare workers (HCWs) were submitted to molecular typing., Results: During 7 years, there were 36 cases of C parapsilosis fungaemia and annual incidence varied from 0 to 19.7 per 1000 admissions. Evaluating 31 neonates with fungemia, the mean age at diagnosis was 19 days. All children except for one were premature; all had received total parenteral nutrition and all but one had used central venous catheter. Three neonates had received antifungal treatment previously to the diagnosis. Thirty-day mortality was 45%. Only lower birthweight was associated with mortality. C parapsilosis species complex was isolated from hand cultures in eight (11%) of the HCWs (one isolate was identified as C orthopsilosis). By molecular typing no HCW isolate was similar to any of the blood isolates., Conclusions: The incidence of C parapsilosis fungemia in a neonatal unit varied widely over 7 years. We observed in our series a higher death rate than that reported in European countries and the USA.

Published
2012
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results