Search

Your search keyword '"Gil Sacaluga, Luis"' showing total 18 results
Start Over Author "Gil Sacaluga, Luis"
18 results on '"Gil Sacaluga, Luis"'

3. Prognosis factors of patients undergoing renal replacement therapy

Author

Universidad de Sevilla. Departamento de Medicina, Universidad de Sevilla. Departamento de Medicina Preventiva y Salud Pública, Muñoz Terol, José Manuel, Rocha Castilla, José Luis, Castro de la Nuez, Pablo, Egea Guerrero, Juan José, Gil Sacaluga, Luis, García Cabrera, Emilio, Vilches Arenas, Ángel, Universidad de Sevilla. Departamento de Medicina, Universidad de Sevilla. Departamento de Medicina Preventiva y Salud Pública, Muñoz Terol, José Manuel, Rocha Castilla, José Luis, Castro de la Nuez, Pablo, Egea Guerrero, Juan José, Gil Sacaluga, Luis, García Cabrera, Emilio, and Vilches Arenas, Ángel

Abstract

Background: Survival in patients with end-stage kidney disease (ESKD) on renal replacement therapy (RRT) is less than that of the general population of the same age, and depends on patient factors, the medical care received, and the type of RRT used. The objective of this study is to analyze the factors associated with survival in patients undergoing RRT. Methods: We conducted a retrospective observational study of adult patients with an incident of ESKD on RRT in Andalusia from 1 January 2008 to 31 December 2018. Patient characteristics, nephrological care received, and survival from the beginning of RRT were evaluated. A survival model for the patient was developed according to the variables studied. Results: A total of 11,551 patients were included. Median survival was 6.8 years (95% CI (6.6; 7.0)). After starting RRT, survival at one year and five years was 88.7% (95% CI (88.1; 89.3)) and 59.4% (95% CI (58.4; 60.4)), respectively. Age, initial comorbidity, diabetic nephropathy, and a venous catheter were independent risk factors. However, non-urgent initiation of RRT and follow-up in consultations for more than six months had a protective effect. It was identified that renal transplantation (RT) was the most influential independent factor in patient survival, with a risk ratio of 0.13 (95% CI (0.11; 0.14)). Conclusions: The receiving of a kidney transplant was the most beneficial modifiable factor in the survival of incident patients on RRT. We consider that the mortality of the renal replacement treatment should be adjusted, taking into account both modifiable and nonmodifiable factors to achieve a more precise and comparable interpretation.

Published
2023

4. Prognosis Factors of Patients Undergoing Renal Replacement Therapy

Author

Muñoz-Terol, José Manuel, Rocha, José L., Castro-de la Nuez, Pablo, Egea-Guerrero, Juan José, Gil-Sacaluga, Luis, García-Cabrera, Emilio, Vilches-Arenas, A., Muñoz-Terol, José Manuel, Rocha, José L., Castro-de la Nuez, Pablo, Egea-Guerrero, Juan José, Gil-Sacaluga, Luis, García-Cabrera, Emilio, and Vilches-Arenas, A.

Abstract

Background: Survival in patients with end-stage kidney disease (ESKD) on renal replacement therapy (RRT) is less than that of the general population of the same age, and depends on patient factors, the medical care received, and the type of RRT used. The objective of this study is to analyze the factors associated with survival in patients undergoing RRT. Methods: We conducted a retrospective observational study of adult patients with an incident of ESKD on RRT in Andalusia from 1 January 2008 to 31 December 2018. Patient characteristics, nephrological care received, and survival from the beginning of RRT were evaluated. A survival model for the patient was developed according to the variables studied. Results: A total of 11,551 patients were included. Median survival was 6.8 years (95% CI (6.6; 7.0)). After starting RRT, survival at one year and five years was 88.7% (95% CI (88.1; 89.3)) and 59.4% (95% CI (58.4; 60.4)), respectively. Age, initial comorbidity, diabetic nephropathy, and a venous catheter were independent risk factors. However, non-urgent initiation of RRT and follow-up in consultations for more than six months had a protective effect. It was identified that renal transplantation (RT) was the most influential independent factor in patient survival, with a risk ratio of 0.13 (95% CI (0.11; 0.14)). Conclusions: The receiving of a kidney transplant was the most beneficial modifiable factor in the survival of incident patients on RRT. We consider that the mortality of the renal replacement treatment should be adjusted, taking into account both modifiable and nonmodifiable factors to achieve a more precise and comparable interpretation.

Published
2023

8. Association of Candidate Gene Polymorphisms With Chronic Kidney Disease: Results of a Case-Control Analysis in the Nefrona Cohort

Author

Valls, Joan, Perez-Guallar, Carles, Cambray, Serafi, Bozic, Milica, Bermudez-Lopez, Marcelino, Fernandez, Elvira, Betriu, Angels, Rodriguez, Isabel, Valdivielso, Jose M., Aladren Regidor, Ma Jose, Almirall, Jaume, Ponz, Esther, Arteaga Coloma, Jesus, Bajo Rubio, Ma Auxiliadora, Diaz, Raquel Raquel, Belart Rodriguez, Montserrat, Gascon, Antonio, Bover Sanjuan, Jordi, Bronsoms Artero, Josep, Cabezuelo Romero, Juan B., Muray Cases, Salome, Calvino Varela, Jesus, Caro Acevedo, Pilar, Carreras Bassa, Jordi, Cases Amenos, Aleix, Masso Jimenez, Elisabet, Moreno Lopez, Rosario, Cigarran Guldris, Secundino, Lopez Prieto, Saray, Comas Mongay, Lourdes, Comerma, Isabel, Compte Jove, Ma Teresa, Cuberes Izquierdo, Marta, de Alvaro, Fernando, Hevia Ojanguren, Covadonga, de Arriba de la Fuente, Gabriel, del Pino y Pino, Ma Dolores, Diaz-Tejeiro Izquierdo, Rafael, Ahijado Hormigos, Francisco, Dotori, Marta, Duarte, Veronica, Estupinan Torres, Sara, Fernandez Reyes, Ma Jose, Fernandez Rodriguez, Ma Loreto, Fernandez, Guillermina, Galan Serrano, Antonio, Garcia Canton, Cesar, Garcia Herrera, Antonio L., Garcia Mena, Mercedes, Gil Sacaluga, Luis, Aguilar, Maria, Gorriz, Jose Luis, Huarte Loza, Emma, Lerma, Jose Luis, Liebana Canada, Antonio, Marin Alvarez, Jesus Pedro, Martin Alemany, Nadia, Martin Garcia, Jesus, Martinez Castelao, Alberto, Martinez Villaescusa, Maria, Martinez, Isabel, Moina Eguren, Inigo, Moreno Los Huertos, Silvia, Mouzo Mirco, Ricardo, Munar Vila, Antonia, Munoz Diaz, Ana Beatriz, Navarro Gonzalez, Juan F., Nieto, Javier, Carreno, Agustin, Novoa Fernandez, Enrique, Ortiz, Alberto, Fernandez, Beatriz, Paraiso, Vicente, Perez Fontan, Miguel, Peris Domingo, Ana, Pinera Haces, Celestino, Prados Garrido, Ma Dolores, Prieto Velasco, Mario, Puig Mari, Carmina, Rivera Gorrin, Maite, Rubio, Esther, Ruiz, Pilar, Salgueira Lazo, Mercedes, Martinez Puerto, Ana Isabel, Sanchez Tomero, Jose Antonio, Sanchez, Jose Emilio, Sans Lorman, Ramon, Saracho, Ramon, Sarrias, Maria, Seron, Daniel, Soler, Maria Jose, Barrios, Clara, Sousa, Fernando, Toran, Daniel, Tornero Molina, Fernando, Uson Carrasco, Jose Javier, Valera Cortes, Ildefonso, Vilaprinyo del Perugia, Ma Merce, Virto Ruiz, Rafael C., Santos Altozano, Carlos, Artigao Rodenas, Miguel, Gil Gil, Ines, Adan Gil, Francisco, Garcia Criado, Emilio, Dura Belinchon, Rafael, Fernandez Toro, Jose Ma, and Divison Garrote, Juan Antonio

Abstract

Chronic kidney disease (CKD) is a major risk factor for end-stage renal disease, cardiovascular disease and premature death. Despite classical clinical risk factors for CKD and some genetic risk factors have been identified, the residual risk observed in prediction models is still high. Therefore, new risk factors need to be identified in order to better predict the risk of CKD in the population. Here, we analyzed the genetic association of 79 SNPs of proteins associated with mineral metabolism disturbances with CKD in a cohort that includes 2, 445 CKD cases and 559 controls. Genotyping was performed with matrix assisted laser desorption ionizationtime of flight mass spectrometry. We used logistic regression models considering different genetic inheritance models to assess the association of the SNPs with the prevalence of CKD, adjusting for known risk factors. Eight SNPs (rs1126616, rs35068180, rs2238135, rs1800247, rs385564, rs4236, rs2248359, and rs1564858) were associated with CKD even after adjusting by sex, age and race. A model containing five of these SNPs (rs1126616, rs35068180, rs1800247, rs4236, and rs2248359), diabetes and hypertension showed better performance than models considering only clinical risk factors, significantly increasing the area under the curve of the model without polymorphisms. Furthermore, one of the SNPs (the rs2248359) showed an interaction with hypertension, being the risk genotype affecting only hypertensive patients. We conclude that 5 SNPs related to proteins implicated in mineral metabolism disturbances (Osteopontin, osteocalcin, matrix gla protein, matrix metalloprotease 3 and 24 hydroxylase) are associated to an increased risk of suffering CKD.

Published
2019

9. Gentamicin as Empirical Treatment in Hemodialysis Patients: Safety, Pharmacokinetics, and Pharmacodynamics

Author

Guisado-Gil, Ana Belén, Herrera‐Hidalgo, Laura, Santos-Rubio, María D., Gil‐Sacaluga, Luis, Molina Gil-Bermejo, José, Lepe, José A., Camacho‐Martínez, Pedro, Gil-Navarro, María Victoria, Guisado-Gil, Ana Belén, Herrera‐Hidalgo, Laura, Santos-Rubio, María D., Gil‐Sacaluga, Luis, Molina Gil-Bermejo, José, Lepe, José A., Camacho‐Martínez, Pedro, and Gil-Navarro, María Victoria

Abstract

The aim of this study was to describe the safety profile and pharmacokinetic/pharmacodynamic parameters in end‐stage renal disease patients who received gentamicin as empirical treatment in catheter‐related bacteremia when they showed infection signs, regardless of the timing of the next HD. Patients received gentamicin 3 mg/kg before blood culture extraction when they showed infection signs and regardless of the timing of next hemodialysis session. Serum concentrations were collected after the gentamicin administration (peak level) and before the next HD (trough level). Toxicities and adverse drug events were registered. The main pharmacokinetic/pharmacodynamic goal for Gram‐negative infections was peak:minimum inhibitory concentration (MIC) ≥10. Sixteen patients were included. Nephrotoxicity was not assessed in this population, and no ototoxicity was found. According to microbial isolation and gentamicin susceptibility, the value of peak:MIC was 5.4 ± 2.0. The administration of gentamicin in these conditions was safe. Estimated pharmacokinetic values were consistent with previous studies and appropriate according to peak:MIC goal for Gram‐negative organisms with MIC ≤1 mg/L.

Published
2019

14. Tratamiento sustitutivo de la insuficiencia renal crónica : diálisis y trasplante renal : proceso asistencial integrado 2ª ed

Author

Pérez Valdivia, Miguel Ángel, Díaz Aunión, María Concepción, Alonso Gil, Manuel, Barrera Becerra, Concepción, Del Pino y Pino, María Dolores, Frutos Sanz, Miguel Ángel, García Álvarez, Teresa María, García Marcos, Sergio Antonio, Gasch Illescas, Antonia, Gil Cunquero, Jose Manuel, Gil Sacaluga, Luis, González Carmelo, Isabel, Huet Ruiz-Matas, Jesús, Ila García, Andrés, Jiménez Jiménez, Sagrario, López Andreu, María, Milán Martín, José Antonio, Muelas Ortega, Francisca, Osman García, Ignacio, Perez Bañasco, Vicente, Pérez Villares, José Miguel, Quirós Ganga, Pedro, Ras Luna, Javier, Remón Rodríguez, César, Ruiz Fuentes, Carmen, and Ruiz Villen, Concepción

Subjects
Guía de práctica clínica, Diseases::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases::Renal Insufficiency::Renal Insufficiency, Chronic [Medical Subject Headings], Health Care::Health Services Administration::Quality of Health Care [Medical Subject Headings], Insuficiencia renal crónica-Terapia, Publication Characteristics::Publication Formats::Guideline::Practice Guideline [Medical Subject Headings], Trasplante de riñón, Andalucía, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Renal Replacement Therapy::Kidney Transplantation [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Renal Replacement Therapy::Renal Dialysis [Medical Subject Headings], Diálisis renal, Calidad de la atención de salud
Abstract

Proceso publicado en la página web de la Consejería de Salud: www.juntadeandalucia.es/salud (Consejería de Salud / Profesionales / Nuestro Compromiso por la Calidad / Procesos Asistenciales Integrados) Yes En esta nueva edición del Proceso Asistencial Integrado, además de proceder a la actualización de todo el contenido científico de diálisis y trasplante renal incluida en la edición de 2005, se ha renovado la descripción de los componentes, profesionales, actividades y características de calidad de cada fase de desarrollo del proceso asistencial, incorporando elementos de seguridad e información a el/la paciente. Se han revisado los indicadores de calidad en función de su interés clínico y la capacidad para ser objetivados y a medida que los grupos profesionales las identifiquen se establecerán aquellas competencias que deben estar presentes para la implantación del proceso. Los conceptos vertidos en este documento son fruto de la experiencia y están fundamentados en la evidencia científica actual disponible, definiéndose las distintas características de calidad de acuerdo con dicha evidencia y, por consenso cuando ésta no exista.

Published
2015

15. Desinfección térmica en hemodiálisis usando el concepto A0 como dosificador.

Author

Toapanta Gaibor, Néstor Gabriel, Gil Sacaluga, Luis, de la Cerda Ojeda, Francisco, Molas Cotén, José Ramón, and Salgueira Lazo, Mercedes

Abstract

Copyright of Nefrologia is the property of Revista Nefrologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019
Full Text
View/download PDF

16. Desinfección térmica en hemodiálisis usando el concepto A0como dosificador

Author

Toapanta Gaibor, Néstor Gabriel, Gil Sacaluga, Luis, de la Cerda Ojeda, Francisco, Molas Cotén, José Ramón, and Salgueira Lazo, Mercedes

Abstract

Los pacientes con enfermedad renal crónica en programa de hemodiálisis se encuentran expuestos a grandes cantidades de agua, ya que esta constituye cerca del 96% del líquido de diálisis. Es conocido que el uso de agua de mejor calidad disminuye el estado de inflamación crónica en los pacientes en diálisis. La desinfección como parte del tratamiento del agua tiene un papel importante para cumplir los estándares de calidad establecidos. En la actualidad, la desinfección por calor es muy recomendable, sin embargo, la dosis no está claramente establecida en la bibliografía. El objetivo de esta revisión es conocer los datos disponibles sobre la dosis de desinfección por calor que se debe utilizar en hemodiálisis, así como presentar nuestra experiencia con este método a una dosis establecida de 12.000 A0.

Published
2019
Full Text
View/download PDF

17. Sistema de Información de la Coordinación Autonómica de Trasplantes de Andalucía (SICATA) : Subsistema de Insuficiencia Renal Crónica : Informe 2011

Author

Castro de la Nuez, Pablo, Gil Sacaluga, Luis, Gentil Govantes, Miguel Angel, and Alonso Gil, Manuel

Subjects
Diseases::Female Urogenital Diseases and Pregnancy Complications::Female Urogenital Diseases::Urologic Diseases::Kidney Diseases::Renal Insufficiency::Renal Insufficiency, Chronic::Kidney Failure, Chronic [Medical Subject Headings], Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings], Diseases::Endocrine System Diseases::Adrenal Gland Diseases::Adrenal Insufficiency [Medical Subject Headings], Insuficiencia Renal Crónica, Health Care::Health Care Facilities, Manpower, and Services::Health Services::Patient Care::Ambulatory Care::Peritoneal Dialysis, Continuous Ambulatory [Medical Subject Headings], Diállisis Renal, Diálisis Peritoneal, Trasplante de Riñon, Andalucía, Fallo Renal Crónico, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Sorption Detoxification::Renal Dialysis [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Urogenital Surgical Procedures::Urologic Surgical Procedures::Kidney Transplantation [Medical Subject Headings]
Abstract

Esta publicación contiene datos de prevalencia, incidencia y mortalidad de los pacientes con insuficiencia renal crónica terminal en tratamiento sustitutivo, residentes en nuestra comunidad. Yes

Published
2012

18. Thermal disinfection in hemodialysis using the A0 concept as dispenser.

Author

Toapanta Gaibor NG, Gil Sacaluga L, de la Cerda Ojeda F, Molas Cotén JR, and Salgueira Lazo M

Subjects
Colony Count, Microbial methods, Disinfection standards, Hepatitis B virus, Humans, Retrospective Studies, Time Factors, Water Microbiology, Disinfection methods, Hemodialysis Solutions standards, Hot Temperature, Renal Dialysis instrumentation, Renal Insufficiency, Chronic therapy, Water standards
Abstract

Patients with chronic kidney disease in the hemodialysis program are exposed to large amounts of water, as this constitutes about 96% of the dialysis fluid. It is known that the use of better quality water decreases the state of chronic inflammation in dialysis patients. Disinfection as part of water treatment plays an important role in meeting the established quality standards; currently, heat disinfection is highly recommended, however its dose is not clearly established in the literature. The objective of this review is to know what is available in the literature on the dose of heat disinfection that should be used in hemodialysis and to present our experience with this method at a set dose of 12.000 A 0 ., (Copyright © 2019 Sociedad Española de Nefrología. Published by Elsevier España, S.L.U. All rights reserved.)

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results