280 results on '"Gill, Deborah R."'
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2. Sendai F/HN pseudotyped lentiviral vector transduces human ciliated and non-ciliated airway cells using α 2,3 sialylated receptors
3. Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus
4. Genomic diversity of SARS-CoV-2 in Oxford during United Kingdom’s first national lockdown
5. Lentiviral and AAV-mediated expression of palivizumab offer protection against Respiratory Syncytial Virus infection
6. Identification of AAV serotypes for lung gene therapy in human embryonic stem cell-derived lung organoids
7. The murine lung as a factory to produce secreted intrapulmonary and circulatory proteins
8. Transgene sequences free of CG dinucleotides lead to high level, long-term expression in the lung independent of plasmid backbone design
9. Type I interferon receptor signalling deficiency results in dysregulated innate immune responses to SARS‐CoV‐2 in mice
10. Progress in Respiratory Gene Therapy
11. Gene therapy for cystic fibrosis lung disease
12. The safety profile of a cationic lipid-mediated cystic fibrosis gene transfer agent following repeated monthly aerosol administration to sheep
13. Correction of a chronic pulmonary disease through lentiviral vector-mediated protein expression
14. Intranasal Lentiviral Vector-Mediated Antibody Delivery Confers Reduction of SARS-CoV-2 Infection in Elderly and Immunocompromised Mice
15. Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis
16. CpG-free plasmid expression cassettes for cystic fibrosis gene therapy
17. The use of CpG-free plasmids to mediate persistent gene expression following repeated aerosol delivery of pDNA/PEI complexes
18. RNA-seq analysis of the human surfactant air-liquid interface culture reveals alveolar type II cell-like transcriptome
19. Lung directed antibody gene transfer confers protection against SARS-CoV-2 infection
20. Lung-targeting lentiviral vector for passive immunisation against influenza
21. Secreted Gaussia luciferase as a sensitive reporter gene for in vivo and ex vivo studies of airway gene transfer
22. The significance of plasmid DNA preparations contaminated with bacterial genomic DNA on inflammatory responses following delivery of lipoplexes to the murine lung
23. Lung directed antibody gene transfer confers protection against SARS-CoV-2 infection.
24. A Phase I/IIa Safety and Efficacy Study of Nebulized Liposome-mediated Gene Therapy for Cystic Fibrosis Supports a Multidose Trial
25. The use of carboxymethylcellulose gel to increase non-viral gene transfer in mouse airways
26. An immunocytochemical assay to detect human CFTR expression following gene transfer
27. Delivery of genes into the CF airway
28. Rapid identification of novel functional promoters for gene therapy
29. Lentiviral and AAV-mediated Expression of Palivizumab Offer protection against Respiratory Syncytial Virus infection
30. A human surfactant B deficiency air-liquid interface cell culture model suitable for gene therapy applications
31. A randomised, double-blind, placebo-controlled phase IIB clinical trial of repeated application of gene therapy in patients with cystic fibrosis
32. Electrohydrodynamic Comminution: A Novel Technique for the Aerosolisation of Plasmid DNA
33. Genome-wide integration site detection using Cas9 enriched amplification-free long-range sequencing
34. Changes in physiological, functional and structural markers of cystic fibrosis lung disease with treatment of a pulmonary exacerbation
35. Assessment of F/HN-Pseudotyped Lentivirus as a Clinically Relevant Vector for Lung Gene Therapy
36. Assessment of CFTR Function after Gene Transfer In Vitro and In Vivo
37. Gene Therapy for Respiratory Diseases: Progress and a Changing Context
38. Identification of AAV serotypes for lung gene therapy in human embryonic stem cell derived lung organoids.
39. Limitations of the Murine Nose in the Development of Nonviral Airway Gene Transfer
40. Plasmid Inhalation: Delivery to the Airways
41. Characterisation of a novel cell division operon in E. coli K-12
42. Electroporation enhances reporter gene expression following delivery of naked plasmid DNA to the lung
43. Human-Specific Cystic Fibrosis Transmembrane Conductance Regulator Antibodies Detect In Vivo Gene Transfer to Ovine Airways
44. Electroporation-mediated interleukin-10 overexpression in skeletal muscle reduces acute rejection in rat cardiac allografts
45. Localised mutagenesis of the fts YEX operon conditionally lethal missense substitutions in the FtsE cell division protein of Escherichia coli are similar to those found in the cystic fibrosis transmembrane conductance regulator protein (CFTR) of human patients
46. Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy
47. Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein
48. Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport
49. Emerging gene therapies for cystic fibrosis
50. Identification of LZTFL1as a candidate effector gene at a COVID-19 risk locus
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