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2 results on '"Giovanni Di, M"'

1. Hemostatic balance in patients with liver cirrhosis: Report of a consensus conference

Author

Angelo, A, Armando, T, Paolo, A, Marco, S, Massimo, P, Edoardo G., G, Oliviero, R, Agostino, C, Daniele, P, David, S, Carlo, M, Stefania, B, Domenico, F, Erica, V, Giovanni Di, M, Paolo, C, Marco, M, Pier Mannuccio, M, Francesco, V, Fagiuoli, S, Angelo Andriulli, Armando Tripodi, Paolo Angeli, Marco Senzolo, Massimo Primignani, Edoardo G. Giannini, Oliviero Riggio, Agostino Colli, Daniele Prati, David Sacerdoti, Carlo Merkel, Stefania Basili, Domenico Ferro, Erica Villa, Giovanni Di Minno, Paolo Caraceni, Marco Marzioni, Pier Mannuccio Mannucci, Francesco Violi, Fagiuoli S, Angelo, A, Armando, T, Paolo, A, Marco, S, Massimo, P, Edoardo G., G, Oliviero, R, Agostino, C, Daniele, P, David, S, Carlo, M, Stefania, B, Domenico, F, Erica, V, Giovanni Di, M, Paolo, C, Marco, M, Pier Mannuccio, M, Francesco, V, Fagiuoli, S, Angelo Andriulli, Armando Tripodi, Paolo Angeli, Marco Senzolo, Massimo Primignani, Edoardo G. Giannini, Oliviero Riggio, Agostino Colli, Daniele Prati, David Sacerdoti, Carlo Merkel, Stefania Basili, Domenico Ferro, Erica Villa, Giovanni Di Minno, Paolo Caraceni, Marco Marzioni, Pier Mannuccio Mannucci, Francesco Violi, and Fagiuoli S

Abstract

Patients with cirrhosis present with hemostatic alterations secondary to reduced availability of pro-coagulant and anti-coagulant factors. The net effect of these changes is a rebalanced hemostatic system. The Italian Association of the Study of the Liver (AISF) and the Italian Society of Internal Medicine (SIMI) promoted a consensus conference on the hemostatic balance in patients with cirrhosis. The consensus process started with the review of the literature by a scientific board of experts and ended with a formal consensus meeting in Rome in December 2014. The statements were graded according to quality of evidence and strength of recommendations, and approved by an independent jury. The statements presented here highlight strengths and weaknesses of current laboratory tests to assess bleeding and thrombotic risk in cirrhotic patients, the pathophysiology of hemostatic perturbations in this condition, and outline the optimal management of bleeding and thrombosis in patients with liver cirrhosis.

Published
2016

2. Hemostatic balance in patients with liver cirrhosis: Report of a consensus conference

Author

Maria Teresa Sartori, Agostino Colli, Francesco Violi, Armando Tripodi, Alessandro Vitale, Pier Mannuccio Mannucci, Paolo Caraceni, Paolo Angeli, Vincenzo La Mura, Cristina Lucidi, Laura Napoleone, Paolo Feltracco, Elvira Grandone, Fabio Piscaglia, Daniele Prati, Marco Marzioni, Massimo Zuin, Angelo Andriulli, Paolo Rebulla, Dario Ribero, Gianluca Svegliati Baroni, Anna Licata, Marco Marietta, Oliviero Riggio, Antonella Tufano, Erica Villa, Marco Senzolo, Filippo Schepis, Antonella Scalera, Sergio Maimone, Massimo Siciliano, Lesley De Pietri, Domenico Ferro, Giovanni Di Minno, Vincenza Calvaruso, Marco Falcone, Edoardo G. Giannini, David Sacerdoti, Valeria Raparelli, Stefania Basili, Filomena Morisco, Salvatore Piano, Carlo Merkel, Massimo Primignani, Andriulli, Angelo, Tripodi, Armando, Angeli, Paolo, Senzolo, Marco, Primignani, Massimo, Giannini, Edoardo G., Riggio, Oliviero, Colli, Agostino, Prati, Daniele, Sacerdoti, David, Merkel, Carlo, Basili, Stefania, Ferro, Domenico, Villa, Erica, Di Minno, Giovanni, Caraceni, Paolo, Marzioni, Marco, Mannucci, Pier Mannuccio, Violi, Francesco, Piscaglia, Fabio, Calvaruso, Vincenza, De Pietri, Lesley, Falcone, Marco, Feltracco, Paolo, Grandone, Elvira, La Mura, Vincenzo, Licata, Anna, Lucidi, Cristina, Maimone, Sergio, Marietta, Marco, Morisco, Filomena, Napoleone, Laura, Piano, Salvatore, Raparelli, Valeria, Rebulla, Paolo, Ribero, Dario, Sartori, Maria Teresa, Scalera, Antonella, Schepis, Filippo, Sicilianom, Massimo, Baroni, Gianluca Svegliati, Tufano, Antonella, Vitale, Alessandro, Zuin, Massimo, DI MINNO, Giovanni, Angelo, A, Armando, T, Paolo, A, Marco, S, Massimo, P, Edoardo G., G, Oliviero, R, Agostino, C, Daniele, P, David, S, Carlo, M, Stefania, B, Domenico, F, Erica, V, Giovanni Di, M, Paolo, C, Marco, M, Pier Mannuccio, M, Francesco, V, Fagiuoli, S, Andriulli, A, Tripodi, A, Angeli, P, Senzolo, M, Primignani, M, Giannini, EG, Riggio, O, Colli, A, Prati, D, Sacerdoti, D, Merkel, C, Basili, S, Ferro, D, Villa, E, Di Minno, G, Caraceni, P, Marzioni, M, Mannucci, PM, Violi, F, Piscaglia, F, Calvaruso, V, De Pietri, L, Falcone, M, Feltracco, P, Grandone, E, La Mura, V, Licata, A, Lucidi, C, Maimone, S, Marietta, M, Morisco, F, Napoleone, L, Piano, S, Raparelli, V, Rebulla, P, Ribero, D, Sartori, M, Scalera, A, Schepis, F, Siciliano, M, Baroni, G.S, Tufano, A, Vitale, A, and Zuin, M

Subjects
Liver Cirrhosis, Cirrhosis, Bleeding, Hemostasis, Thrombosis, Hepatology, Gastroenterology, Settore MED/09 - Medicina Interna, Anticoagulants, Coagulants, Drug Monitoring, Esophageal and Gastric Varices, Gastrointestinal Hemorrhage, Humans, Postoperative Hemorrhage, Blood Coagulation Tests, 0302 clinical medicine, Esophageal and Gastric Varice, Blood coagulation test, Consensus conference, Optimal management, Coagulant, 030220 oncology & carcinogenesis, Thrombosi, 030211 gastroenterology & hepatology, Human, medicine.medical_specialty, Liver Cirrhosi, NO, 03 medical and health sciences, Internal medicine, medicine, In patient, Intensive care medicine, Cirrhosi, business.industry, Anticoagulant, Hemostasi, Blood Coagulation Test, medicine.disease, Surgery, business
Abstract

Patients with cirrhosis present with hemostatic alterations secondary to reduced availability of pro-coagulant and anti-coagulant factors. The net effect of these changes is a rebalanced hemostatic system. The Italian Association of the Study of the Liver (AISF) and the Italian Society of Internal Medicine (SIMI) promoted a consensus conference on the hemostatic balance in patients with cirrhosis. The consensus process started with the review of the literature by a scientific board of experts and ended with a formal consensus meeting in Rome in December 2014. The statements were graded according to quality of evidence and strength of recommendations, and approved by an independent jury. The statements presented here highlight strengths and weaknesses of current laboratory tests to assess bleeding and thrombotic risk in cirrhotic patients, the pathophysiology of hemostatic perturbations in this condition, and outline the optimal management of bleeding and thrombosis in patients with liver cirrhosis.

Published
2016

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