1. Double-blind study of the analgesic effect of indoprofen (K 4277)
- Author
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Virginio Mandelli, Franco Conti, Giuseppe Stefanelli, Mario Randelli, Giulio Corvi, and Luciano M. Fuccella
- Subjects
Adult ,Male ,Analgesic effect ,Indoles ,Time Factors ,Palliative care ,Pain ,Placebo ,Placebos ,Single oral dose ,Double blind study ,Humans ,Medicine ,Pharmacology (medical) ,In patient ,Neoplasm Metastasis ,Aged ,Pharmacology ,Analgesics ,Clinical Trials as Topic ,Phenylpropionates ,business.industry ,Palliative Care ,Indoprofen ,Middle Aged ,medicine.disease ,Anesthesia ,Neuralgia ,Female ,business ,medicine.drug - Abstract
In a double-blind study, indoprofen was superior to placebo in decreasing pain in patients with primary and metastatic cancer and with neuralgia. A single oral dose of 200 mg was more active than a 100-mg dose. The preferences of patients proved to be a more sensitive parameter in this study than scores of pain intensity, pain relief, and other related measurements (SPID, TOTPAR, and Peak PID).
- Published
- 1975
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