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This article reports the results of an analysis of five Big Deal electronic journal packages to which Hofstra University's Axinn Library subscribes. COUNTER usage reports were used to judge the value of each Big Deal. Limitations of usage statistics are also discussed. In the end, the author concludes that four of the five Big Deals are good deals for Hofstra University, offers suggestions for using usage statistics, and stresses the importance of each library making its own judgment as to the value and sustainability of Big Deal journal packages.

This study analyzes citations from The International Journal of Business Communication to reveal characteristics of the interdisciplinarity of the field of business communication and provide insight and guidance for collection development in this area. A list of most cited journals and books is provided. Subject analysis is included to determine discipline distribution, and collection development recommendations are made. A snapshot analysis is undertaken to determine what percentage of top cited journals are available with full-text at present in commonly-held subscription databases. An annotated bibliography of a selection of more cited and/or seminal books is provided, of which some may lie outside the typical expertise of business and communication librarians. [ABSTRACT FROM AUTHOR]

The article focuses on providing protection to child informants and witnesses whose testimony or status as a witness renders them unsafe in the U.S. It mentions about views of U.S. Supreme Court in Chambers v. Mississippi addressing criminal trial process; and stories of child witnesses and informants murdered as a result of their participation in the criminal justice system.

Background: Cruciferous vegetables have been associated with the chemoprevention of cancer. Epigenetic regulators have been identified as important targets for prostate cancer chemoprevention. Treatment of human prostate cancer cells with sulforaphane (SFN), a chemical from broccoli and broccoli sprouts, inhibits epigenetic regulators such as histone deacetylase (HDAC) enzymes, but it is not known whether consumption of a diet high in broccoli sprouts impacts epigenetic mechanisms in an in vivo model of prostate cancer., Objective: In the transgenic adenocarcinoma of the mouse prostate (TRAMP) model, we tested the hypothesis that a broccoli sprout diet suppresses prostate cancer, inhibits HDAC expression, alters histone modifications, and changes the expression of genes regulated by HDACs., Methods: TRAMP mice were fed a 15% broccoli sprout or control AIN93G diet; tissue samples were collected at 12 and 28 wk of age., Results: Mice fed broccoli sprouts had detectable amounts of SFN metabolites in liver, kidney, colon, and prostate tissues. Broccoli sprouts reduced prostate cancer incidence and progression to invasive cancer by 11- and 2.4-fold at 12 and 28 wk of age, respectively. There was a significant decline in HDAC3 protein expression in the epithelial cells of prostate ventral and anterior lobes at age 12 wk. Broccoli sprout consumption also decreased histone H3 lysine 9 trimethylation in the ventral lobe (age 12 wk), and decreased histone H3 lysine 18 acetylation in all prostate lobes (age 28 wk). A decline in p16 mRNA levels, a gene regulated by HDAC3, was associated with broccoli sprout consumption, but no significant changes were noted at the protein level., Conclusions: Broccoli sprout intake was associated with a decline in prostate cancer occurrence and HDAC3 protein expression in the prostate, extending prior work that implicated loss of HDAC3/ corepressor interactions as a key preventive mechanism by SFN in vivo.