1. Global Epidemiology of Diphtheria, 2000–20171
- Author
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Thomas Cherian, Adam MacNeil, Stephen C. Hadler, Colleen Scott, Kristie E.N. Clarke, and Tejpratap Tiwari
- Subjects
Microbiology (medical) ,medicine.medical_specialty ,Vaccination Coverage ,Adolescent ,030231 tropical medicine ,Booster dose ,Global Health ,complex mixtures ,World health ,Corynebacterium diphtheria ,03 medical and health sciences ,0302 clinical medicine ,Public health surveillance ,Environmental health ,Epidemiology ,Medicine ,data quality ,Humans ,030212 general & internal medicine ,bacteria ,Child ,Diphtheria-Tetanus-Pertussis Vaccine ,Booster (rocketry) ,business.industry ,Incidence (epidemiology) ,Diphtheria ,Incidence ,Infant ,medicine.disease ,global ,public health surveillance ,Infectious Diseases ,Global Epidemiology of Diphtheria, 2000–2017 ,Data quality ,Child, Preschool ,Population Surveillance ,Synopsis ,epidemiology ,business - Abstract
In 2017, a total of 8,819 cases of diphtheria were reported worldwide, the most since 2004. However, recent diphtheria epidemiology has not been well described. We analyzed incidence data and data from the literature to describe diphtheria epidemiology. World Health Organization surveillance data were 81% complete; completeness varied by region, indicating underreporting. As national diphtheria–tetanus–pertussis (DTP) 3 coverage increased, the proportion of case-patients 15 years of age, consistent with waning vaccine immunity. Global DTP3 coverage is suboptimal. Attaining high DTP3 coverage and implementing recommended booster doses are necessary to decrease diphtheria incidence. Collection and use of data on subnational and booster dose coverage, enhanced laboratory capacity, and case-based surveillance would improve data quality.
- Published
- 2019