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2. Diet quality and associations with lactate and metabolic syndrome in bipolar disorder

Author

Etain, B., Olié, E., Leboyer, M., Haffen, E., Llorca, P.M., Barteau, V., Bensalem, S., Godin, O., Laouamri, H., Souryis, K., Hotier, S., Pelletier, A., Hergeta, F., Petrucci, J., Willaume, L., Bellivier, F., Hennion, V., Marlinge, E., Meheust, J., Richard, A., Carminati, M., Francisque, H., Dubertret, C., Mazer, N., Portalier, C., Scognamiglio, C., Bing, A., Laurent, P., Gard, S., M'Bailara, K., Elkael, C., Hoorelbeke, F., Minois, I., Sportich, J., Da Ros, N., Boukhobza, L., Courtet, P., Denat, S., Deffinis, B., Ducasse, D., Gachet, M., Lengvenyté, A., Molière, F., Nass, L., Tarquini, G., Lefrere, A., Moreau, E., Pastol, J., Groppi, F., Polomeni, H., Bauberg, J., Lescalier, L., Muraccioli, I., Suray, A., Cohen, R., Kahn, J.P., Milazzo, M., Wajsbrot-Elgrabli, O., Bougerol, T., Pouchon, A., Bertrand, A., Fredembach, B., Suisse, A., Denoual, Q., Polosan, M., Galliot, A.M., Brehon, L., Bonny, G., Durand, L., Feuga, V., Kayser, N., Roux, P., Aubin, V., Cussac, I., Dupont, M.A., Loftus, J., Medecin, I., Samalin, L., Mennetrier, M., Bonnet, T., Lacelle, D., Vayssié, M., Beal, C., Blanc, O., Zachos, Kassandra A., Godin, Ophelia, Choi, Jaehyoung, Jung, Jae H., Aouizerate, Bruno, Aubin, Valérie, Bellivier, Frank, Belzeaux-R, Raoul, Courtet, Philippe, Dubertret, Caroline, Etain, Bruno, Haffen, Emmanuel, Lefrere A, Antoine, Llorca, Pierre-Michel, Olié, Emilie, Polosan, Mircea, Samalin, Ludovic, Schwan, Raymund, Roux, Paul, Barau, Caroline, Richard, Jean Romain, Tamouza, Ryad, Leboyer, Marion, and Andreazza, Ana C.

Published
2024
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3. Mitochondrial Biomarkers and Metabolic Syndrome in Bipolar Disorder

Author

Etain, B., Olié, E., Leboyer, M., Haffen, E., Llorca, PM, Barteau, V., Bensalem, S., Godin, O., Laouamri, H., Souryis, K., Hotier, S., Pelletier, A., Hergeta, F., Petrucci, J., Willaume, L., Bellivier, F., Hennion, V., Marlinge, E., Meheust, J., Richard, A., Carminati, M., Francisque, H., Dubertret, C., Mazer, N., Portalier, C., Scognamiglio, C., Bing, A., Laurent, P., Gard, S., M'Bailara, K., Elkael, C., Hoorelbeke, F., Minois, I., Sportich, J., Da Ros, N., Boukhobza, L., Courtet, P., Denat, S., Deffinis, B., Ducasse, D., Gachet, M., Lengvenyté, A., Molière, F., Nass, L., Tarquini, G., Lefrere, A., Moreau, E., Pastol, J., Groppi, F., Polomeni, H., Bauberg, J, Lescalier, L., Muraccioli, I., Suray, A., Cohen, R., Kahn, J.P., Milazzo, M., Wajsbrot-Elgrabli, O., Bougerol, T., Pouchon, A., Bertrand, A, Fredembach, B., Suisse, A., Denoual, Q, Polosan, M, Galliot, A.M., Brehon, L., Bonny, G, Durand, L, Feuga, V, Kayser, N., Roux, P., Aubin, V., Cussac, I., Dupont, M.A, Loftus, J., Medecin, I., Samalin, L., Llorca, PM., Mennetrier, M., Bonnet, T., Lacelle, D., Vayssié, M., Beal, C., Blanc, O., Zachos, Kassandra A., Choi, Jaehyoung, Godin, Ophelia, Chernega, Timofei, Kwak, Haejin Angela, Jung, Jae H., Aouizerate, Bruno, Aubin, Valérie, Bellivier, Frank, Belzeaux-R, Raoul, Courtet, Philippe, Dubertret, Caroline, Etain, Bruno, Haffen, Emmanuel, Lefrere A, Antoine, Llorca, Pierre-Michel, Olié, Emilie, Polosan, Mircea, Samalin, Ludovic, Schwan, Raymund, Roux, Paul, Barau, Caroline, Richard, Jean Romain, Tamouza, Ryad, Leboyer, Marion, and Andreazza, Ana C.

Published
2024
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4. Comparative analysis of anticholinergic burden scales to explain iatrogenic cognitive impairment and self-reported side effects in the euthymic phase of bipolar disorders: Results from the FACE-BD cohort

Author

Etain, B., Olié, E., Leboyer, M., Haffen, E., Llorca, P.M., Barteau, V., Bensalem, S., Godin, O., Laouamri, H., Souryis, K., Hotier, S., Pelletier, A., Drancourt, N., Sanchez, J.P., Saliou, E., Hebbache, C., Petrucci, J., Willaume, L., Bourdin, E., Bellivier, F., Carminati, M., Marlinge, E., Meheust, J., Hennion, V., Francisque, H., Aouizerate, B., Da Ros, N., Desage, A., Elkael, C., Gard, S., Hoorelbeke, F., M'bailara, K., Minois, I., Sportich, J., Boukhobza, L., Benramdane, M., Courtet, P., Deffinis, B., Denat, S., Ducasse, D., Gachet, M., Molière, F., Nass, L., Tarquini, G., Belzeaux, R., Cermolacce, M., Groppi, F., Moreau, E., Lefrere, A., Lescalier, L., Pastol, J., Viglianese, N., Cohen, R., Gross, G., Schwan, R., Schwitzer, T., Wajsbrot-Elgrabli, O., Bougerol, T., Fredembach, B., Denoual, Q, Bertrand, A., Pouchon, A., Polosan, M., Bonny, G., Brehon, L., Durand, L., Feuga, V., Galliot, A.M., Kayser, N., Passerieux, C., Roux, P., Aubin, V., Cussac, I., Dupont, M.A., Loftus, J., Medecin, I., Dubertret, C., Mazer, N., Portalier, C., Scognamiglio, C., Bing, A., Laurent, P., Llorca, PM., Samalin, L., Foures, L., Lacelle, D., Pires, S., Doriat, C., Blanc, O., Bennabi, D., Nicolier, M., Vidal, N., Brunet-Gouet, E., Frileux, S., D'Amato, T., Januel, D., and Walter, M.

Published
2023
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5. Early-life factors associated with increased risk of disability pension in the national real-world schizophrenia FACE-SZ cohort study

Author

Fond, G., Dubreucq, J., de Verville, P. L. Sunhary, Godin, O., Andrieu-Haller, C., Berna, F., Aouizerate, B., Capdevielle, D., Chereau, I., Clauss-Kobayashi, J., Coulon, N., Dorey, J. M., Dubertret, C., Mallet, J., Misdrahi, D., Passerieux, C., Rey, R., Pignon, B., Schürhoff, F., Urbach, M., Llorca, P. M., Lançon, C., and Boyer, L.

Published
2022
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8. The impact of parent history of severe mental illness on schizophrenia outcomes: results from the real-world FACE-SZ cohort

Author

Garosi, A., Sunhary de Verville, P. L., Etchecopar-etchart, D., Richieri, R., Godin, O., Schürhoff, F., Berna, F., Aouizerate, B., Capdevielle, D., Chereau, I., Clauss-Kobayashi, J., Dorey, J. M., Dubertret, C., Coulon, N., Leignier, S., Mallet, J., Misdrahi, D., Passerieux, C., Rey, R., Szoke, A., Urbach, M., Leboyer, M., Llorca, P. M., Lançon, C., Boyer, L., and Fond, G.

Published
2022
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9. Redefining peripheral inflammation signature in schizophrenia based on the real-world FACE-SZ cohort

Author

Llorca, P.M., Lançon, C., Boyer, L., Fond, G., Sunhary de Verville, P.L., Richieri, R., Etchecopar-Etchart, D., Korchia, T., Faugere, M., Godin, O., Schürhoff, F., Berna, F., Aouizerate, B., Capdevielle, D., Chereau, I., Clauss-Kobayashi, J., Coulon, N., Dorey, J.M., Dubertret, C., Dubreucq, J., Mallet, J., Misdrahi, D., Passerieux, C., Pignon, B., Rey, R., Urbach, M., and Leboyer, M.

Published
2021
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10. Cognitive impairments in treatment-resistant depression: Results from the French cohort of outpatients (FACE-DR)

Author

Vancappel, A, Dansou, Y, Godin, O, Haffen, E, Yrondi, A, Stéphan, F, Richieri, R, Molière, F, Horn, M, Allauze, E, Genty, JB, Bouvard, A, Dorey, JM, Meyrel, M, Camus, V, Fond, G, Péran, B, Walter, M, Anguill, L, Scotto d'Apollonia, C, Nguon, AS, Fredembach, B, Holtzmann, J, Vilà, E, Petrucci, J, Rey, Etain, B, Carminati, M, Courtet, P, Vaiva, G, Llorca, PM, Leboyer, M, Aouizerate, B, Bennabi, D, and El-Hage, W

Published
2021
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11. Recommendations of the schizophrenia expert center network for the screening prevention and treatment of sleep disorders based on the results from the real-world schizophrenia FACE-SZ national cohort

Author

Sunhary de Verville, P.L., Etchecopar-Etchart, D., Richieri, R., Godin, O., Schürhoff, F., Berna, F., Aouizerate, B., Capdevielle, D., Chereau, I., D'Amato, T., Dubertret, C., Dubreucq, J., Leignier, S., Mallet, J., Misdrahi, D., Passerieux, C., Pignon, B., Rey, R., Urbach, M., Vidailhet, P., Leboyer, M., Llorca, P.M., Lançon, C., Boyer, L., and Fond, G.

Published
2021
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12. Clinical characteristics of bipolar disorders with postpartum depressive onset

Author

Etain, B., Henry, C., Olié, E., Leboyer, M., Haffen, E., Llorca, P.M., Barteau, V., Bensalem, S., Godin, O., Laouamri, H., Souryis, K., Hotier, S., Pelletier, A., Drancourt, N., Sanchez, J.P., Saliou, E., Hebbache, C., Petrucci, J., Willaume, L., Bourdin, E., Bellivier, F., Carminati, M., Marlinge, E., Meheust, J., Antoniol, B., Desage, A., Gard, S., Jutant, A., Mbailara, K., Minois, I., Zanouy, L., Abettan, C., Bardin, L., Cazals, A., Courtet, P., Deffinis, B., Ducasse, D., Gachet, M., Henrion, A., Martinerie, E., Molière, F., Noisette, B., Tarquini, G., Azorin, J.M., Belzeaux, R., Correard, N., Consoloni, J.L., Groppi, F., Lescalier, L., Montant, J., Rebattu, M., Viglianese, N., Cohen, R., Kahn, J.P., Milazzo, M., Wajsbrot-Elgrabli, O., Bougerol, T., Fredembach, B., Suisse, A., Halili, B., Pouchon, A., Polosan, M., Galliot, A.M., Grévin, I., Cannavo, A.S., Kayser, N., Passerieux, C., Roux, P., Aubin, V., Cussac, I., Dupont, M.A., Loftus, J., Medecin, I., Dubertret, C., Mazer, N., Portalier, C., Scognamiglio, C., Bing, A., Tebeka, Sarah, Godin, Ophelia, Mazer, Nicolas, Bellivier, Frank, Courtet, Philippe, Etain, Bruno, Gard, Sébastien, Leboyer, Marion, Llorca, Pierre-Michel, Loftus, Joséphine, Olié, Emilie, Passerieux, Christine, Polosan, Mircea, Schwan, Raymund, Belzeaux, Raoul, and Dubertret, Caroline

Published
2021
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14. Clinical predictors of recurrences in bipolar disorders type 1 and 2: A FACE-BD longitudinal study

Author

Etain, B., Olié, E., Leboyer, M., Llorca, P.M., Henry, C., Barteau, V., Bensalem, S., Godin, O., Laouamri, H., Souryis, K., Hotier, S., Pelletier, A., Sanchez, J.P., Saliou, E., Hebbache, C., Petrucci, J., Willaume, L., Bourdin, E., Bellivier, F., Carminati, M., Maruani, J., Marlinge, E., Meheust, J., Antoniol, B., Desage, A., Gard, S., Jutant, A., Mbailara, K., Minois, I., Zanouy, L., Abettan, C., Bardin, L., Cazals, A., Courtet, P., Deffinis, B., Ducasse, D., Gachet, M., Henrion, A., Martinerie, E., Molière, F., Noisette, B., Tarquini, G., Azorin, J.M., Belzeaux, R., Correard, N., Consoloni, J.L., Groppi, F., Lescalier, L., Montant, J., Rebattu, M., Viglianese, N., Cohen, R., Gross, G., Schwan, R., Schwitzer, T., Wajsbrot-Elgrabli, O., Bougerol, T., Fredembach, B., Suisse, A., Halili, B., Gaoua, Z., Polosan, M., Cannavo, A.S., Galliot, A.M., Grévin, I., Kayser, N., Liaskovski, G., Passerieux, C., Roux, P., Aubin, V., Cussac, I., Dupont, M.A., Loftus, J., Medecin, I., Dubertret, C., Mazer, N., Portalier, C., Scognamiglio, C., Bing, A., and Aouizerate, B.

Published
2021
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15. Evolution and characteristics of the use of valproate in women of childbearing age with bipolar disorder: Results from the FACE-BD cohort

Author

Samalin, L., Godin, O., Olié, E., Etain, B., Henry, C., Pelletier, A., Poinso, F., Encely, L., Mazer, N., Roux, P., Loftus, J, Gard, S., Bennabi, D., Polosan, M., Schwitzer, T., Aubin, V., Schwan, R., Passerieux, C., Bougerol, T., Dubertret, C., Aouizerate, B., Haffen, E., Courtet, P., Bellivier, F., Leboyer, M., Llorca, P.M., and Belzeaux, R.

Published
2020
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16. Major depression, sleep, hostility and body mass index are associated with impaired quality of life in schizophrenia. Results from the FACE-SZ cohort.

Author

Fond, G., Korchia, T., Sunhary de Verville, P.L., Godin, O., Schürhoff, F., Berna, F., André, M., Aouizerate, B., Capdevielle, D., Chereau, I., D'Amato, T., Dubertret, C., Dubreucq, J., Leignier, S., Mallet, J., Misdrahi, D., Passerieux, C., Pignon, B., Rey, R., Szoke, A., Urbach, M., Vidailhet, P., Leboyer, M., Llorca, P.M., Lançon, C., and Boyer, L.

Published
2020
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17. Confirmations, advances and recommendations for the daily care of schizophrenia based on the French national FACE-SZ cohort

Author

Fond, G., Godin, O., Schürhoff, F., Berna, F., André, M., Aouizerate, B., Capdevielle, D., Chereau, I., D’ Amato, T., Dubertret, C., Dubreucq, J., Faget, C., Lançon, C., Leignier, S., Mallet, J., Misdrahi, D., Passerieux, C., Pignon, B., Rey, R., Szoke, A., Urbach, M., Vidailhet, P., Leboyer, M., Boyer, L., and Llorca, P.M.

Published
2020
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18. Comparative analysis of anticholinergic burden scales to explain iatrogenic cognitive impairment and self-reported side effects in the euthymic phase of bipolar disorders: Results from the FACE-BD cohort

Author

Vidal, N., primary, Brunet-Gouet, E., additional, Frileux, S., additional, Aouizerate, B., additional, Aubin, V., additional, Belzeaux, R., additional, Courtet, P., additional, D'Amato, T., additional, Dubertret, C., additional, Etain, B., additional, Haffen, E., additional, Januel, D., additional, Leboyer, M., additional, Lefrere, A., additional, Llorca, P.M., additional, Marlinge, E., additional, Olié, E., additional, Polosan, M., additional, Schwan, R., additional, Walter, M., additional, Passerieux, C., additional, Roux, P., additional, Barteau, V., additional, Bensalem, S., additional, Godin, O., additional, Laouamri, H., additional, Souryis, K., additional, Hotier, S., additional, Pelletier, A., additional, Drancourt, N., additional, Sanchez, J.P., additional, Saliou, E., additional, Hebbache, C., additional, Petrucci, J., additional, Willaume, L., additional, Bourdin, E., additional, Bellivier, F., additional, Carminati, M., additional, Meheust, J., additional, Hennion, V., additional, Francisque, H., additional, Da Ros, N., additional, Desage, A., additional, Elkael, C., additional, Gard, S., additional, Hoorelbeke, F., additional, M'bailara, K., additional, Minois, I., additional, Sportich, J., additional, Boukhobza, L., additional, Benramdane, M., additional, Deffinis, B., additional, Denat, S., additional, Ducasse, D., additional, Gachet, M., additional, Molière, F., additional, Nass, L., additional, Tarquini, G., additional, Cermolacce, M., additional, Groppi, F., additional, Moreau, E., additional, Lescalier, L., additional, Pastol, J., additional, Viglianese, N., additional, Cohen, R., additional, Gross, G., additional, Schwitzer, T., additional, Wajsbrot-Elgrabli, O., additional, Bougerol, T., additional, Fredembach, B., additional, Denoual, Q, additional, Bertrand, A., additional, Pouchon, A., additional, Bonny, G., additional, Brehon, L., additional, Durand, L., additional, Feuga, V., additional, Galliot, A.M., additional, Kayser, N., additional, Cussac, I., additional, Dupont, M.A., additional, Loftus, J., additional, Medecin, I., additional, Mazer, N., additional, Portalier, C., additional, Scognamiglio, C., additional, Bing, A., additional, Laurent, P., additional, Llorca, PM., additional, Samalin, L., additional, Foures, L., additional, Lacelle, D., additional, Pires, S., additional, Doriat, C., additional, Blanc, O., additional, Bennabi, D., additional, and Nicolier, M., additional

Published
2023
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19. Sexual dysfunctions are associated with major depression, chronic inflammation and anticholinergic consumption in the real-world schizophrenia FACE-SZ national cohort

Author

Fond, G., Godin, O., Dumontaud, M., Faget, C., Schürhoff, F., Berna, F., Aouizerate, B., Capdevielle, D., Chereau, I., D'Amato, T., Dubertret, C., Dubreucq, J., Leignier, S., Mallet, J., Misdrahi, D., Passerieux, C., Rey, R., Schandrin, A., Szoke, A., Urbach, M., Vidailhet, P., Leboyer, M., Lançon, C., Boyer, L., and Llorca, P.M.

Published
2019
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20. Machine learning for predicting psychotic relapse at 2 years in schizophrenia in the national FACE-SZ cohort

Author

Fond, G., Bulzacka, E., Boucekine, M., Schürhoff, F., Berna, F., Godin, O., Aouizerate, B., Capdevielle, D., Chereau, I., D'Amato, T., Dubertret, C., Dubreucq, J., Faget, C., Leignier, S., Lançon, C., Mallet, J., Misdrahi, D., Passerieux, C., Rey, R., Schandrin, A., Urbach, M., Vidailhet, P., Leboyer, M., Boyer, L., and Llorca, P.M.

Published
2019
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22. Hypovitaminosis D is associated with depression and anxiety in schizophrenia: Results from the national FACE-SZ cohort.

Author

Fond, G, Godin, O, Schürhoff, F, Berna, F, Bulzacka, E, Andrianarisoa, M, Brunel, L, Aouizerate, B, Capdevielle, D, Chereau, I, Coulon, N, D'Amato, T, Dubertret, C, Dubreucq, J, Faget, C, Lançon, C, Leignier, S, Mallet, J, Misdrahi, D, Passerieux, C, Rey, R, Schandrin, A, Urbach, M, Vidailhet, P, Leboyer, M, Boyer, L, and Llorca, PM

Published
2018
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23. Incidence and predictors of metabolic syndrome onset in individuals with bipolar disorders: A longitudinal study from the FACE‐BD cohort.

Author

Godin, O., Olié, E., Fond, G., Aouizerate, B., Aubin, V., Bellivier, F., Belzeaux, R., Courtet, P., Dubertret, C., Haffen, E., Lefrere, A., Llorca, P. M., Polosan, M., Roux, P., Samalin, L., Schwan, R., Etain, B., Leboyer, M., Llorca, PM, and Barteau, V.

Subjects
*BIPOLAR disorder, *METABOLIC syndrome, *ALCOHOLISM, *SLEEP interruptions, *LONGITUDINAL method
Abstract

Introduction: Metabolic syndrome (MetS) is a cluster of components including abdominal obesity, hyperglycemia, hypertension, and dyslipidemia. MetS is highly prevalent in individuals with bipolar disorders (BD) with an estimated global rate of 32.6%. Longitudinal data on incident MetS in BD are scarce and based on small sample size. The objectives of this study were to estimate the incidence of MetS in a large longitudinal cohort of 1521 individuals with BD and to identify clinical and biological predictors of incident MetS. Methods: Participants were recruited from the FondaMental Advanced Center of Expertise for Bipolar Disorder (FACE‐BD) cohort and followed‐up for 3 years. MetS was defined according to the International Diabetes Federation criteria. Individuals without MetS at baseline but with MetS during follow‐up were considered as having incident MetS. A logistic regression model was performed to estimate the adjusted odds ratio and its corresponding 95% confidence interval (CI) for an association between each factor and incident MetS during follow‐up. We applied inverse probability‐of‐censoring weighting method to minimize selection bias due to loss during follow‐up. Results: Among individuals without MetS at baseline (n = 1521), 19.3% developed MetS during follow‐up. Multivariable analyses showed that incident MetS during follow‐up was significantly associated with male sex (OR = 2.2, 95% CI = 1.7–3.0, p < 0.0001), older age (OR = 2.14, 95% CI = 1.40–3.25, p = 0.0004), presence of a mood recurrence during follow‐up (OR = 1.91, 95% CI = 1.22–3.00, p = 0.0049), prolonged exposure to second‐generation antipsychotics (OR = 1.56, 95% CI = 0.99, 2.45, p = 0.0534), smoking status at baseline (OR = 1.30, 95% CI = 1.00–1.68), lifetime alcohol use disorders (OR = 1.33, 95% CI = 0.98–1.79), and baseline sleep disturbances (OR = 1.04, 95% CI = 1.00–1.08), independently of the associations observed for baseline MetS components. Conclusion: We observed a high incidence of MetS during a 3 years follow‐up (19.3%) in individuals with BD. Identification of predictive factors should help the development of early interventions to prevent or treat early MetS. [ABSTRACT FROM AUTHOR]

Published
2024
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24. Latent toxoplasma infection in real-world schizophrenia: Results from the national FACE-SZ cohort

Author

Andrianarisoa, M., Aouizerate, B., Bazin, N., Berna, F., Blanc, O., Brunel, L., Bulzacka, E., Capdevielle, D., Chereau-Boudet, I., Chesnoy-Servanin, G., Coulon, N., Danion, J.M., D'Amato, T., Deloge, A., Denizot, H., Dorey, J.M., Dubertret, C., Dubreucq, J., Faget, C., Fluttaz, C., Fond, G., Fonteneau, S., Gabayet, F., Giraud-Baro, E., Jarroir, M., Leignier, S., Lacelle, D., Lançon, C., Laouamri, H., Leboyer, M., Le Gloahec, T., Le Strat, Y., Llorca, P.M., Mallet, J., Metairie, E., Misdrahi, D., Offerlin-Meyer, I., Passerieux, C., Peri, P., Pires, S., Portalier, C., Ramet, L., Rey, R., Roman, C., Schandrin, A., Schürhoff, F., Tessier, A., Tronche, A.M., Urbach, M., Vaillant, F., Vehier, A., Vidailhet, P., Vilà, E., Yazbek, H., Zinetti-Bertschy, A., Boyer, L., Godin, O., and Chereau, I.

Published
2018
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25. Influence of Venus and Mars in the cognitive sky of schizophrenia. Results from the first-step national FACE-SZ cohort

Author

Andrianarisoa, M., Aouizerate, B., Berna, F., Blanc, O., Brunel, L., Bulzacka, E., Capdevielle, D., Chereau-Boudet, I., Chesnoy-Servanin, G., Danion, Jm, D'Amato, T., Deloge, A., Delorme, C., Denizot, H., Dorey, J.M., Dubertret, C., Dubreucq, J., Faget, C., Fluttaz, C., Fond, G., Fonteneau, S., Gabayet, F., Giraud-Baro, E., Hardy-Bayle, M.C., Lacelle, D., Lançon, C., Laouamri, H., Leboyer, M., Le Gloahec, T., Le Strat, Y., Llorca, Mallet, J., Metairie, E., Misdrahi, D., Offerlin-Meyer, I., Passerieux, C., Peri, P., Pires, S., Portalier, C., Rey, R., Roman, C., Sebilleau, M., Schandrin, A., Schurhoff, F., Tessier, A., Tronche, Am, Urbach, M., Vaillant, F., Vehier, A., Vidailhet, P., Vilà, E., Yazbek, H., Zinetti-Bertschy, A., Boyer, L., Godin, O., Llorca, P.M., Chereau, I., Lancon, C., Roux, P., and Schürhoff, F.

Published
2018
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26. Towards an improved access to psychiatric rehabilitation: availability and effectiveness at 1-year follow-up of psychoeducation, cognitive remediation therapy, cognitive behaviour therapy and social skills training in the FondaMental Advanced Centers of Expertise-Schizophrenia (FACE-SZ) national cohort

Author

Dubreucq, Julien, Ycart, B., Gabayet, F., Perier, C. C., Hamon, A., Llorca, P. M., Boyer, L., Godin, O., Bulzacka, E., Andrianarisoa, M., Aouizerate, B., Berna, F., Brunel, L., Capdevielle, D., Chereau, I., D’Amato, T., Dubertret, C., Faget, C., Mallet, J., Misdrahi, D., Passerieux, C., Rey, R., Richieri, R., Schandrin, A., Schürhoff, F., Urbach, M., Vidailhet, P., Giraud-Baro, E., Fond, G., and FACE-SZ (FondaMental Academic Centers of Expertise for Schizophrenia) group

Published
2019
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27. Childhood trauma, dimensions of psychopathology and the clinical expression of bipolar disorders: A pathway analysis

Author

Henry, C., Etain, B., Leboyer, M., Laouamri, H., Souryis, K., Godin, O., Raust, A., Sportiche, S., Geoffroy, P.A., Aouizerate, B., Desage, A., Olie, E., Ducasse, D., Moliere, F., Belzeaux, R., Viglianaise, N., Lescalier, L., Job, S., Cohen, R., Wajsbrot-Elgrabli, O., Polosan, M., Garcon, S., Hardy-Bayle, M.C., Roux, P., Kayser, N., Grevin, I., Loftus, J., Albertini, L., Lajnef, M., Aubin, V., Azorin, J.M., Bellivier, F., Bougerol, T., Courtet, P., Gard, S., Kahn, J.P., and Passerieux, C.

Published
2017
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28. Predictors of rapid high weight gain in schizophrenia: Longitudinal analysis of the French FACE-SZ cohort

Author

Andrianarisoa, M., Aouizerate, B., Berna, F., Blanc, O., Brunel, L., Bulzacka, E., Capdevielle, D., Chereau-Boudet, I., Chesnoy-Servanin, G., Danion, J.M., D'Amato, T., Deloge, A., Delorme, C., Denizot, H., Dorey, J.M., Dubertret, C., Dubreucq, J., Faget, C., Fluttaz, C., Fond, G., Fonteneau, S., Gabayet, F., Giraud-Baro, E., Hardy-Bayle, M.C., Lacelle, D., Lançon, C., Laouamri, H., Leboyer, M., Le Gloahec, T., Le Strat, Y., Llorca, P.M., Mallet, J., Metairie, E., Misdrahi, D., Offerlin-Meyer, I., Passerieux, C., Peri, P., Pires, S., Portalier, C., Rey, R., Roman, C., Sebilleau, M., Schandrin, A., Schürhoff, F., Tessier, A., Tronche, A.M., Urbach, M., Vaillant, F., Vehier, A., Vidailhet, P., Vilain, J., Vilà, E., Yazbek, H., Zinetti-Bertschy, A., Godin, O., Boyer, L., Richieri, R., and Costagliola, D.

Published
2017
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29. Childhood trauma, depression and negative symptoms are independently associated with impaired quality of life in schizophrenia. Results from the national FACE-SZ cohort

Author

Andrianarisoa, M., Aouizerate, B., Berna, F., Blanc, O., Brunel, L., Bulzacka, E., Capdevielle, D., Chereau-Boudet, I., Chesnoy-Servanin, G., Danion, J.M., D'Amato, T., Deloge, A., Delorme, C., Denizot, H., Dorey, J.M., Dubertret, C., Dubreucq, J., Faget, C., Fluttaz, C., Fond, G., Fonteneau, S., Gabayet, F., Giraud-Baro, E., Hardy-Bayle, M.C., Lacelle, D., Lançon, C., Laouamri, H., Leboyer, M., Le Gloahec, T., Le Strat, Y., Llorca, P.M., Mallet, J., Metairie, E., Misdrahi, D., Offerlin-Meyer, I., Passerieux, C., Peri, P., Pires, S., Portalier, C., Rey, R., Roman, C., Sebilleau, M., Schandrin, A., Schurhoff, F., Tessier, A., Tronche, A.M., Urbach, M., Vaillant, F., Vehier, A., Vidailhet, P., Vilà, E., Yazbek, H., Zinetti-Bertschy, A., Boyer, L., Godin, O., Richieri, R., and Schürhoff, F.

Published
2017
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30. Relationships between low-grade peripheral inflammation and psychotropic drugs in schizophrenia: results from the national FACE-SZ cohort

Author

Fond, G., Resseguier, N., Schürhoff, F., Godin, O., Andrianarisoa, M., Brunel, L., Bulzacka, E., Aouizerate, B., Berna, F., Capdevielle, D., Chereau, I., D’Amato, T., Dubertret, C., Dubreucq, J., Faget, C., Gabayet, F., Lançon, C., Llorca, P. M., Mallet, J., Misdrahi, D., Passerieux, C., Rey, R., Schandrin, A., Urbach, M., Vidailhet, P., Boyer, L., Leboyer, M., and the FACE-SZ (FondaMental Academic Centers of Expertise for Schizophrenia) group

Published
2018
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31. Clinical and biological features associated to bipolar disorder with comorbid migraine: results from the FACE-BD cohort

Author

Patoz, M.-C., primary, Godin, O., additional, Moisset, X., additional, Chabert, J., additional, M’Bailara, K., additional, Etain, B., additional, Belzeaux, R., additional, Dubertret, C., additional, Haffen, E., additional, Schwan, R., additional, Roux, P., additional, Polosan, M., additional, Aubin, V., additional, Leboyer, M., additional, Courtet, P., additional, Olie, E., additional, Llorca, P.-M., additional, and Samalin, L., additional

Published
2023
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32. Substance use disorders in bipolar patients with a painful expression

Author

Chabert, J., primary, Icick, R., additional, Cabé, J., additional, Patoz, M.-C., additional, Moisset, X., additional, Godin, O., additional, Gard, S., additional, Loftus, J., additional, Aubin, V., additional, Belzeaux, R., additional, Dubertret, C., additional, Lestrat, Y., additional, Mazer, N., additional, De Premorel, A., additional, Roux, P., additional, Polosan, M., additional, Schwitzer, T., additional, Aouizerate, B., additional, Isabelle, B., additional, Etain, B., additional, Moirand, R., additional, Olié, E., additional, Haffen, E., additional, Leboyer, M., additional, Courtet, P., additional, Llorca, P.-M., additional, Brousse, G., additional, and Samalin, L., additional

Published
2023
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33. Differential effects of childhood trauma and cannabis use disorders in patients suffering from schizophrenia

Author

Baudin, G., Godin, O., Lajnef, M., Aouizerate, B., Berna, F., Brunel, L., Capdevielle, D., Chereau, I., Dorey, J.M., Dubertret, C., Dubreucq, J., Faget, C., Fond, G., Gabayet, F., Laouamri, H., Lancon, C., Le Strat, Y., Tronche, A.M., Misdrahi, D., Rey, R., Passerieux, C., Schandrin, A., Urbach, M., Vidalhet, P., Llorca, P.M., and Schürhoff, F.

Published
2016
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34. Peripheral sub-inflammation is associated with antidepressant consumption in schizophrenia. Results from the multi-center FACE-SZ data set

Author

Fond, G., Godin, O., Brunel, L., Aouizerate, B., Berna, F., Bulzacka, E., Capdevielle, D., Chereau, I., Dorey, J.M., Dubertret, C., Dubreucq, J., Faget, C., Gabayet, F., Le Strat, Y., Micoulaud-Franchi, J.A., Misdrahi, D., Rey, R., Richieri, R., Passerieux, C., Schandrin, A., Schürhoff, F., Tronche, A.M., Urbach, M., Vidalhet, P., Llorca, P.M., and Leboyer, M.

Published
2016
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35. Metabolic syndrome, abdominal obesity and hyperuricemia in schizophrenia: Results from the FACE-SZ cohort

Author

Aouizerate, B., Berna, F., Blanc, O., Brunel, L., Bulzacka, E., Capdevielle, D., Chereau-Boudet, I., Chesnoy-Servanin, G., Danion, J.M., D'Amato, T., Deloge, A., Delorme, C., Denizot, H., Depradier, M., Dorey, J.M., Dubertret, C., Dubreucq, J., Faget, C., Fluttaz, C., Fond, G., Fonteneau, S., Gabayet, F., Giraud-Baro, E., Hardy-Bayle, M.C., Lacelle, D., Lançon, C., Laouamri, H., Leboyer, M., Le Gloahec, T., Le Strat, Y., Llorca, P.M., Metairie, E., Misdrahi, D., Offerlin-Meyer, I., Passerieux, C., Peri, P., Pires, S., Portalier, C., Rey, R., Roman, C., Sebilleau, M., Schandrin, A., Schürhoff, F., Tessier, A., Tronche, A.M., Urbach, M., Vaillant, F., Vehier, A., Vidailhet, P., Vilà, E., Yazbek, H., Zinetti-Bertschy, A., Godin, O., Gaman, A., Chereau, I., Richieri, R., Vidalhet, P., and Girerd, N.

Published
2015
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37. Birth by cesarean section and schizophrenia: results from the multicenter FACE-SZ data-set

Author

Fond, G., Bulzacka, E., Boyer, L., Llorca, P. M., Godin, O., Brunel, L., Andrianarisoa, M. G., Aouizerate, B., Berna, F., Capdevielle, D., Chereau, I., Denizot, H., Dorey, J. M., Dubertret, C., Dubreucq, J., Faget, C., Gabayet, F., Le Strat, Y., Micoulaud-Franchi, J. A., Misdrahi, D., Rey, R., Richieri, R., Roger, M., Passerieux, C., Schandrin, A., Urbach, M., Vidalhet, P., Schürhoff, F., Leboyer, M., Aouizerate, B., Berna, F., Blanc, O., Brunel, L., Bulzacka, E., Capdevielle, D., Chereau-Boudet, I., Chesnoy-Servanin, G., Danion, J. M., D’Amato, T., Deloge, A., Delorme, C., Denizot, H., De Pradier, M., Dorey, J. M., Dubertret, C., Dubreucq, J., Faget, C., Fluttaz, C., Fond, G., Fonteneau, S., Gabayet, F., Giraud-Baro, E., Hardy-Bayle, M. C., Lacelle, D., Lançon, C., Laouamri, H., Leboyer, M., Le Gloahec, T., Le Strat, Y., Llorca, P. M., Metairie, E., Misdrahi, D., Offerlin-Meyer, I., Passerieux, C., Peri, P., Pires, S., Portalier, C., Rey, R., Roman, C., Sebilleau, M., Schandrin, A., Schurhoff, F., Tessier, A., Tronche, A. M., Urbach, M., Vaillant, F., Vehier, A., Vidailhet, P., Vilà, E., Yazbek, H., Zinetti-Bertschy, A., and FondaMental Academic Centers of Expertise for Schizophrenia (FACE-SZ) Group

Published
2017
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38. Chronic low-grade peripheral inflammation is associated with severe nicotine dependence in schizophrenia: results from the national multicentric FACE-SZ cohort

Author

Fond, G., Berna, F., Andrianarisoa, M., Godin, O., Leboyer, M., Brunel, L., Aouizerate, B., Capdevielle, D., Chereau, I., D’Amato, T., Denizot, H., Dubertret, C., Dubreucq, J., Faget, C., Gabayet, F., Llorca, P. M., Mallet, J., Misdrahi, D., Passerieux, C., Richieri, R., Rey, R., Schandrin, A., Urbach, M., Vidailhet, P., Boyer, L., Schürhoff, F., and The FACE-SZ (FondaMental Academic Centers of Expertise for Schizophrenia) group

Published
2017
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40. Benzodiazepine long-term administration is associated with impaired attention/working memory in schizophrenia: results from the national multicentre FACE-SZ data set

Author

Fond, Guillaume, Berna, F., Boyer, L., Godin, O., Brunel, L., Andrianarisoa, M., Aouizerate, B., Capdevielle, D., Chereau, I., Danion, J. M., Dubertret, C., Dubreucq, J., Faget, C., Gabayet, F., Le Gloahec, T., Llorca, P. M., Mallet, J., Misdrahi, D., Rey, R., Richieri, R., Passerieux, C., Portalier, C., Roux, P., Vehier, A., Yazbek, H., Schürhoff, F., Bulzacka, E., Andrianarisoa, Méja, Aouizerate, Bruno, Berna, Fabrice, Blanc, Olivier, Brunel, Lore, Bulzacka, Ewa, Capdevielle, Delphine, Chéreau-Boudet, Isabelle, Chesnoy-Servanin, Gabrielle, Danion, Jean-Marie, D’Amato, Thierry, Deloge, Arnaud, Delorme, Claire, Denizot, Hélène, Dorey, Jean-Michel, Dubertret, Caroline, Dubreucq, Julien, Faget, Catherine, Fluttaz, Cécile, Fond, Guillaume, Fonteneau, Sandrine, Gabayet, Franck, Giraud-Baro, Elisabeth, Hardy-Baylé, Marie-Christine, Lacelle, Delphine, Lançon, Christophe, Laouamri, Hakim, Leboyer, Marion, Le Gloahec, Tifenn, Le Strat, Yann, Llorca, Pierre-Michel, Mallet, Jasmina, Metairie, Emeline, Misdrahi, David, Offerlin-Meyer, Isabelle, Passerieux, Christine, Peri, Pauline, Pires, Sylvie, Portalier, Céline, Rey, Romain, Roman, Céline, Sebilleau, Mathilde, Schandrin, Aurélie, Schurhoff, Franck, Tessier, Arnaud, Tronche, Anne-Marie, Urbach, Mathieu, Vaillant, Florence, Vehier, Aurélie, Vidailhet, Pierre, Vilà, Estelle, Yazbek, Hanan, Zinetti-Bertschy, Anna, and The FACE-SZ (FondaMental Academic Centers of Expertise for Schizophrenia) group

Published
2017
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42. Low‐Frequency Wave Activity in the Ocean—Ross Ice Shelf—Atmosphere System.

Author

Zabotin, N., Godin, O. A., Bromirski, P. D., Jee, G., Lee, W. S., Yun, S., and Zabotina, L.

Subjects
*ICE shelves, *OCEAN waves, *ATMOSPHERIC circulation, *GEOPHYSICAL instruments, *SEISMOMETERS, *ATMOSPHERIC waves, *SOIL vibration
Abstract

The main subject of this study is the low‐frequency (with the periods longer than 2 hr) wave processes in the coupled regional system of the Ross Ice Shelf (RIS), the Ross Sea and the atmosphere above them. We investigate possible causal relationships between the wave activity in the three media using a unique set of geophysical instruments: a hydrophone measuring pressure variations on the seafloor, a network of seismometers measuring vertical displacements of the RIS surface, and a Dynasonde system measuring wave characteristics at the ionospheric altitudes. We present an extension of the previously introduced theoretical model of the coupled resonance vibrations of the RIS that quantifies the connection between the ocean tide and the resonance vibrations of the RIS. The ocean tide is confirmed as the most significant source of excitation of the resonances. Analysis of average power spectra in year‐long data sets reveals multiple harmonics of the tide (eight) detected by the RIS seismometers while only three are detected by the seafloor sensor. This may represent a confirmation of the effect of resonance‐related broadband amplification predicted by the model. Several peaks in the spectrum of RIS vibrations have periods different from the periods of nearby tidal constituents and may be associated with broad‐scale resonance RIS vibrations. Resonances may play a role in maintaining the coupled atmosphere‐ocean wave activity. Our results reveal a statistically significant correlation between the spectra of the vertical displacements of the RIS and the spectra of the atmospheric waves. Plain Language Summary: This study explores how low‐frequency waves interact in the Ross Ice Shelf, the Ross Sea, and the atmosphere above them. By using a unique set of tools like hydrophones, seismometers, and a Dynasonde system, the researchers investigate the connection between waves in these three areas. They expand on a previous theoretical model, confirming that ocean tides are the main source of these interactions. The study finds that the ice shelf picks up more tidal harmonics than the seafloor sensor, which might support the idea of resonance‐related amplification. Additionally, some vibrations in the ice shelf have different periods than nearby tidal movements, which could be due to broad‐scale resonance vibrations. These resonances might play a role in maintaining the overall wave activity in the atmosphere and ocean. The research shows a significant correlation between the ice shelf's vertical movements and the atmospheric waves. Key Points: Ocean tides represent a major source of energy for exciting resonance vibrations of the Ross Ice Shelf (RIS)There is an empirical evidence for resonance‐related amplification effect predicted by the theory of forced ice shelf vibrationsSpectral correlation results confirm existence of the wave coupling above the noise level between atmosphere, ocean and the RIS [ABSTRACT FROM AUTHOR]

Published
2023
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43. The impact of parent history of severe mental illness on schizophrenia outcomes: results from the real-world FACE-SZ cohort.

Author

Garosi, A., Sunhary de Verville, P. L., Etchecopar-etchart, D., Richieri, R., Godin, O., Schürhoff, F., Berna, F., Aouizerate, B., Capdevielle, D., Chereau, I., Clauss-Kobayashi, J., Dorey, J. M., Dubertret, C., Coulon, N., Leignier, S., Mallet, J., Misdrahi, D., Passerieux, C., Rey, R., and Szoke, A.

Subjects
MENTAL illness, BIPOLAR disorder, MENTAL depression, SCHIZOPHRENIA, SCHIZOAFFECTIVE disorders, ADULT children
Abstract

Parent history of severe mental illness (PHSMI) may have long-term consequences in adult offspring due to genetic and early environmental factors in preliminary studies. To compare the outcomes associated in subjects with PHSMI to those in patients without PHSMI. The participants with schizophrenia and schizoaffective disorders were recruited in the ongoing FACE-SZ cohort at a national level (10 expert centers) and evaluated with a 1-day-long standardized battery of clinician-rated scales and patient-reported outcomes. PHSMI was defined as history of schizophrenia or bipolar disorders in at least one parent and was included as explanatory variable in multivariate models. Of the 724 included patients, 78 (10.7%) subjects were classified in the PHSMI group. In multivariate analyses, PHSMI patients had a better insight into schizophrenia and the need for treatment and reported more often childhood trauma history compared to patients without PHSMI. More specifically, those with paternal history of SMI reported more severe outcomes (increased childhood physical and emotional abuses, comorbid major depression and psychiatric hospitalizations). PHSMI is associated with increased risk of childhood trauma, major depressive disorder and psychiatric hospitalization and better insight in individuals with schizophrenia. Specific public health prevention programs for parents with SMI should be developed to help protect children from pejorative psychiatric outcomes. PHSMI may also explain in part the association between better insight and increased depression in schizophrenia. [ABSTRACT FROM AUTHOR]

Published
2023
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45. Immuno-metabolic profile of patients with psychotic disorders and metabolic syndrome. Results from the FACE-SZ cohort

Author

Foiselle, Marianne, primary, Barbosa, Susana, additional, Godin, Ophélia, additional, Wu, Ching-Lien, additional, Boukouaci, Wahid, additional, Andre, Myrtille, additional, Aouizerate, Bruno, additional, Berna, Fabrice, additional, Barau, Caroline, additional, Capdevielle, Delphine, additional, Vidailhet, Pierre, additional, Chereau, Isabelle, additional, Davidovic, Laetitia, additional, Dorey, Jean-Michel, additional, Dubertret, Caroline, additional, Dubreucq, Julien, additional, Faget, Catherine, additional, Fond, Guillaume, additional, Leigner, Sylvain, additional, Llorca, Pierre-Michel, additional, Mallet, Jasmina, additional, Misdrahi, David, additional, Martinuzzi, Emanuela, additional, Passerieux, Christine, additional, Rey, Romain, additional, Pignon, Baptiste, additional, Urbach, Mathieu, additional, Schürhoff, Franck, additional, Glaichenhaus, Nicolas, additional, Leboyer, Marion, additional, Tamouza, Ryad, additional, Berna, F., additional, Haffen, E., additional, Leboyer, M., additional, Llorca, P.M., additional, Schürhoff, F., additional, Barteau, V., additional, Bensalem, S., additional, Godin, O., additional, Laouamri, H., additional, Souryis, K., additional, Offerlin-Meyer, I., additional, Pignon, B., additional, Szöke, A., additional, Aouizerate, B., additional, Deloge, A., additional, Misdrahi, D., additional, Vilà, E., additional, Blanc, O., additional, Chéreau, I., additional, Denizot, H., additional, Honciuc, R.M., additional, Lacelle, D., additional, Pires, S., additional, Dubertret, C., additional, Mallet, J., additional, Portalier, C., additional, Dubreucq, J., additional, Fluttaz, C., additional, Gabayet, F., additional, Roman, C., additional, Chesnoy-Servanin, G., additional, D'Amato, T., additional, Dorey, J.M., additional, Rey, R., additional, Vehier, A., additional, Lançon, C., additional, Faget, C., additional, Metairie, E., additional, Peri, P., additional, Vaillant, F., additional, Boyer, L., additional, Fond, G., additional, Vidailhet, P., additional, Zinetti-Bertschy, A., additional, Capdevielle, D., additional, Yazbek, H., additional, Esselin, S., additional, Jarroir, M., additional, Passerieux, C., additional, and Urbach, M., additional

Published
2022
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46. Key findings on bipolar disorders from the longitudinal FondaMental Advanced Center of Expertise-Bipolar Disorder (FACE-BD) cohort

Author

Leboyer, M., primary, Godin, O., additional, Llorca, P.M., additional, Aubin, V., additional, Bellivier, F., additional, Belzeaux, R., additional, Courtet, P., additional, Costagliola, D., additional, Dubertret, C., additional, M'Bailara, K., additional, Haffen, E., additional, Henry, C., additional, Laouamri, H., additional, Passerieux, C., additional, Pelletier, A., additional, Polosan, M., additional, Roux, P., additional, Schwan, R., additional, Samalin, L., additional, Olié, E., additional, Etain, Bruno, additional, Etain, B., additional, Leboyer, M., additional, Barteau, V., additional, Bensalem, S., additional, Souryis, K., additional, Hotier, S., additional, Sanchez, J.P., additional, Saliou, E., additional, Hebbache, C., additional, Petrucci, J., additional, Wuillaume, L., additional, Bourdin, E., additional, Carminati, M., additional, Hennion, V., additional, Marlinge, E., additional, Meheust, J., additional, Zekri, C., additional, Desage, A., additional, Gard, S., additional, Minois, I., additional, Sportich, J., additional, Zanouy, L., additional, Abettan, C., additional, Bardin, L., additional, Cazals, A., additional, Deffinis, B., additional, Ducasse, D., additional, Gachet, M., additional, Henrion, A., additional, Martinerie, E., additional, Molière, F., additional, Noisette, B., additional, and Tarquini, E.G., additional

Published
2022
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48. Predictors of Functional Impairment in Bipolar Disorder: Results from 13 Cohorts from Seven Countries by The Global Bipolar Cohort Collaborative

Author

Burdick, KE, Millett, CE, Yocum, AK, Altimus, CM, Andreassen, OA, Aubin, V, Belzeaux, R, Berk, Michael, Biernacka, JM, Blumberg, HP, Cleare, AJ, Diaz‐Byrd, C, Dubertret, C, Etain, B, Eyler, L, Forester, BP, Fullerton, JM, Frye, MA, Gard, S, Godin, O, Haffen, E, Klaus, F, Lagerberg, TV, Leboyer, M, Martinez‐Aran, A, McElroy, S, Mitchell, PB, Olie, E, Olorunfemi, P, Passerieux, C, Peters, A, Pham, DL, Polosan, M, Potter, JR, Sajatovic, M, Samalin, L, Schwan, R, Shanahan, M, Solé, B, Strawbridge, R, Stuart, Amanda, Torres, I, Ueland, T, Vieta, E, Williams, Lana, Wrobel, Anna, Yatham, LN, Young, AH, Nierenberg, A, McInnis, MG, Burdick, KE, Millett, CE, Yocum, AK, Altimus, CM, Andreassen, OA, Aubin, V, Belzeaux, R, Berk, Michael, Biernacka, JM, Blumberg, HP, Cleare, AJ, Diaz‐Byrd, C, Dubertret, C, Etain, B, Eyler, L, Forester, BP, Fullerton, JM, Frye, MA, Gard, S, Godin, O, Haffen, E, Klaus, F, Lagerberg, TV, Leboyer, M, Martinez‐Aran, A, McElroy, S, Mitchell, PB, Olie, E, Olorunfemi, P, Passerieux, C, Peters, A, Pham, DL, Polosan, M, Potter, JR, Sajatovic, M, Samalin, L, Schwan, R, Shanahan, M, Solé, B, Strawbridge, R, Stuart, Amanda, Torres, I, Ueland, T, Vieta, E, Williams, Lana, Wrobel, Anna, Yatham, LN, Young, AH, Nierenberg, A, and McInnis, MG

Published
2022

49. Cognitive profiles in euthymic patients with bipolar disorders: results from the FACE‐BD cohort

Author

Roux, Paul, Raust, Aurélie, Cannavo, Anne Sophie, Aubin, Valérie, Aouizerate, Bruno, Azorin, Jean‐Michel, Bellivier, Frank, Belzeaux, Raoul, Bougerol, Thierry, Cussac, Iréna, Courtet, Philippe, Etain, Bruno, Gard, Sébastien, Job, Sophie, Kahn, Jean‐Pierre, Leboyer, Marion, Olié, Emilie, Henry, Chantal, Passerieux, Christine, Godin, O., Laouamri, H., Ngo‐Nguyen, N., Boudebesse, C., Choppin, S., Leduc, A, Bernardon, C., Biseul, I., Lépine, J. P., Leroux, M., Nieto, I, Seguin, P., Sportiche, S., Antoniol, B., Desage, A., Jutant, A., Mbailara, K., Minois, I., Zanouy, L., Chaib, L., Kindelberger, C., Kaouachi, Z., Molière, F., Seyller, M., Tarquini, G., Corréard, N., Cohen, R., Kieffer, P., Wajsbrot‐Elgrabli, O., De Pourtales, M. A., Fredembach, B., Garçon, S., Polosan, M., Galiot, A.M., Grévin, I., Hardy‐Bayle, M. C., Homassel, A.S., Kayser, N., Albertini, L., Beetz, E., Loftus, J., and Medecin, I.

Published
2017
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50. Influence of childhood maltreatment on prevalence, onset and persistence of psychiatric comorbidities and suicide attempts in bipolar disorders

Author

Grillault Laroche, D., Godin, O., Dansou, Y., Belzeaux, R., Aouizerate, B., Burté, T., Courtet, Philippe, Dubertret, C., Haffen, E., Llorca, P.M., Olié, Émilie, Roux, P., Polosan, M., Schwan, R., Leboyer, M., Bellivier, F., Marie-Claire, C., Etain, B., Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Optimisation thérapeutique en Neuropsychopharmacologie (OPTeN (UMR_S_1144 / U1144)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), CHU Henri Mondor [Créteil], Fondation FondaMental [Créteil], Assistance Publique - Hôpitaux de Marseille (APHM), Institut de Neurosciences de la Timone (INT), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Centre hospitalier Charles Perrens [Bordeaux], Nutrition et Neurobiologie intégrée (NutriNeuro), Université de Bordeaux (UB)-Institut Polytechnique de Bordeaux-Ecole nationale supérieure de chimie, biologie et physique-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre Hospitalier Princesse Grace, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Institut de Génomique Fonctionnelle (IGF), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Université Paris Cité (UPCité), Hôpital Louis Mourier - AP-HP [Colombes], Institut de psychiatrie et neurosciences de Paris (IPNP - U1266 Inserm), Centre d'Investigation Clinique de Besançon (Inserm CIC 1431), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement français du sang [Bourgogne-Franche-Comté] (EFS BFC)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), CHU Clermont-Ferrand, Université Clermont Auvergne (UCA), Centre Hospitalier de Versailles André Mignot (CHV), Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, [GIN] Grenoble Institut des Neurosciences (GIN), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes (UGA), Université de Lorraine (UL), Centre Psychothérapique de Nancy [Laxou] (CPN), ANR-11-IDEX-0004,SUPER,Sorbonne Universités à Paris pour l'Enseignement et la Recherche(2011), ANR-10-COHO-0010,Psy-COH,FondaMental-Cohortes(2010), Neurobiologie des interactions cellulaires et neurophysiopathologie - NICN (NICN), Centre National de la Recherche Scientifique (CNRS)-Université de la Méditerranée - Aix-Marseille 2, AP-HP, Groupe Hospitalo-Universitaire AP-HP Nord, DMU ESPRIT, service de Psychiatrie et Addictologie, Hôpital Louis Mourier, Colombes, Inserm U1266, 178, rue des Renouillers, 92700 Colombes, France, UFR de Médecine Paris Nord, Université de Paris, 16, rue Henri Huchard, 75018 Paris, France., Groupe de Recherche en Psychologie Sociale (GRePS), Université Lumière - Lyon 2 (UL2), Praticien Hospitalier Universitaire, CPN Laxou, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPC), Guerineau, Nathalie C., Sorbonne Universités à Paris pour l'Enseignement et la Recherche - - SUPER2011 - ANR-11-IDEX-0004 - IDEX - VALID, Cohortes - FondaMental-Cohortes - - Psy-COH2010 - ANR-10-COHO-0010 - COHO - VALID, CHU Henri Mondor, Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement français du sang [Bourgogne-Franche-Comté] (EFS [Bourgogne-Franche-Comté])-Université de Franche-Comté (UFC), and Hôpital Charles Perrens

Subjects
bipolar disorder, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, childhood trauma, [SDV]Life Sciences [q-bio], childhood maltreatment, prevalence, substance use, Suicide, Attempted, sequence, anxiety, comorbidities, Suicidal Ideation, [SDV] Life Sciences [q-bio], Psychiatry and Mental health, [SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health, mental disorders, Humans, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Child Abuse, Child, network analysis, suicide, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

BackgroundPsychiatric comorbidities and suicide attempts are highly prevalent in Bipolar Disorders (BD). We examined the associations between childhood maltreatment, psychiatric comorbidities, and suicide attempts, in terms of lifetime prevalence, sequence of onset, and current symptoms.MethodsWe assessed 3,047 individuals with BD for suicide attempts, anxiety disorders, substance use disorders, and eating disorders. Participants completed a self-report for the assessment of childhood maltreatment. Associations between childhood maltreatment and characteristics of comorbidities (lifetime prevalence, current symptoms, and age at onset) were examined using logistic regressions and network analyses.ResultsPsychiatric comorbidities were frequent with a mean number per individual of 1.23 (SD = 1.4). Most comorbidities occurred prior to the onset of BD. Participants who reported higher levels of childhood maltreatment had more frequent and multiple comorbidities, which were also more currently active at inclusion. Childhood maltreatment did not decrease the age of onset of comorbidities, but was associated with a faster accumulation of comorbidities prior to the onset of BD. Logistic regression and network analyses showed that emotional abuse and sexual abuse might play a prominent role in the lifetime prevalence of psychiatric comorbidities and suicide attempts.ConclusionsChildhood maltreatment was associated with suicide attempts, and with frequent, multiple, and persistent psychiatric comorbidities that accumulated more rapidly prior to the onset of BD. Hence, childhood maltreatment should be systematically assessed in individuals with BD, in particular when the course of the disorder is characterized by a high comorbid profile or by a high suicidality.

Published
2022

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