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17 results on '"Goetz, Giles W."'

1. Allelic diversification after transposable element exaptation promoted gsdf as the master sex determining gene of sablefish

Author

Herpin, Amaury, primary, Schartl, Manfred, additional, Depincé, Alexandra, additional, Guiguen, Yann, additional, Bobe, Julien, additional, Hua-Van, Aurélie, additional, Hayman, Edward S., additional, Octavera, Anna, additional, Yoshizaki, Goro, additional, Nichols, Krista M., additional, Goetz, Giles W., additional, and Luckenbach, J. Adam, additional

Published
2021
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7. Allelic diversification after transposable element exaptation promoted gsdfas the master sex determining gene of sablefish

Author

Herpin, Amaury, Schartl, Manfred, Depincé, Alexandra, Guiguen, Yann, Bobe, Julien, Hua-Van, Aurélie, Hayman, Edward S., Octavera, Anna, Yoshizaki, Goro, Nichols, Krista M., Goetz, Giles W., and Luckenbach, J. Adam

Abstract

Concepts of evolutionary biology suggest that morphological change may occur by rare punctual but rather large changes, or by more steady and gradual transformations. It can therefore be asked whether genetic changes underlying morphological, physiological, and/or behavioral innovations during evolution occur in a punctual manner, whereby a single mutational event has prominent phenotypic consequences, or if many consecutive alterations in the DNA over longer time periods lead to phenotypic divergence. In the marine teleost, sablefish (Anoplopoma fimbria), complementary genomic and genetic studies led to the identification of a sex locus on the Y Chromosome. Further characterization of this locus resulted in identification of the transforming growth factor, beta receptor 1a(tgfbr1a) gene, gonadal somatic cell derived factor(gsdf), as the main candidate for fulfilling the master sex determining (MSD) function. The presence of different X and Y Chromosome copies of this gene indicated that the male heterogametic (XY) system of sex determination in sablefish arose by allelic diversification. The gsdfYgene has a spatio-temporal expression profile characteristic of a male MSD gene. We provide experimental evidence demonstrating a pivotal role of a transposable element (TE) for the divergent function of gsdfY. By insertion within the gsdfYpromoter region, this TE generated allelic diversification by bringing cis-regulatory modules that led to transcriptional rewiring and thus creation of a new MSD gene. This points out, for the first time in the scenario of MSD gene evolution by allelic diversification, a single, punctual molecular event in the appearance of a new trigger for male development.

Published
2021
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8. Bacteroidales diversity in ring-billed gulls (Laurus delawarensis) residing at Lake Michigan beaches

Author

Jeter, Sonja N., McDermott, Colleen M., Bower, Patricia A., Kinzelman, Julie L., Bootsma, Melinda J., Goetz, Giles W., and McLellan, Sandra L.

Subjects
Lake Michigan -- Natural resources, Anaerobic bacteria -- Environmental aspects, Anaerobic bacteria -- Genetic aspects, Gulls -- Physiological aspects, Gulls -- Diseases and pests, Intestines -- Microbiology, Intestines -- Research, Biological sciences
Published
2009

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