140 results on '"Goff, Dane A."'
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2. Optimization of Pharmacokinetic and In Vitro Safety Profile of a Series of Pyridine Diamide Indirect AMPK Activators
3. Supplementary Materials, Figure Legends 1-6 from R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
4. Data from R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
5. Supplementary Figure 5 from R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
6. Supplementary Tables 1-3 from R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
7. Supplementary Figure 3 from R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
8. Supplementary Figure 1 D-H from R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
9. Supplementary Figure 1 A-C from R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
10. Supplementary Figure 6 from R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
11. Supplementary Figure 4 from R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
12. Supplementary Figure 2 from R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
13. Diverse alkaloid-like structures from a common building block
14. Efforts towards a Noyori reduction of a 3-fluorpiperidin-4-one with dynamic kinetic resolution
15. Nmr Structural Characterization of Oligo-N-Substituted Glycine Lead Compounds from a Combinatorial Library
16. CYCLOPETIDE ALKALOIDS. SYNTHETIC, SPECTROSCOPIC AND CONFORMATIONAL STUDIES OF PHENCYCLOPEPTINE MODEL COMPOUNDS
17. Selective Glycogen Synthase Kinase 3 Inhibitors Potentiate Insulin Activation of Glucose Transport and Utilization In Vitro and In Vivo
18. Discovery of dual Axl/VEGF-R2 inhibitors as potential anti-angiogenic and anti-metastatic drugs for cancer chemotherapy
19. Developing DYRK inhibitors derived from the meridianins as a means of increasing levels of NFAT in the nucleus
20. Synthesis, Binding Mode, and Antihyperglycemic Activity of Potent and Selective (5-Imidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino)ethyl]amine Inhibitors of Glycogen Synthase Kinase 3
21. Combinatorial synthesis of indolizines on solid support
22. The preparation of 2,4-disubstituted thiazoles on solid support
23. Abstract 3021: Development of small molecule direct AMPK activators for the treatment of cancer
24. Selective Inhibitors of Glycogen Synthase Kinase 3 with Effects on Insulin Signaling
25. Global metabolite profiling of mice with high-fat diet-induced obesity chronically treated with AMPK activators R118 or metformin reveals tissue-selective alterations in metabolic pathways
26. Exercise performance and peripheral vascular insufficiency improve with AMPK activation in high-fat diet-fed mice
27. ChemInform Abstract: Enantioselective Synthesis of cis-3-Fluoropiperidin-4-ol, a Building Block for Medicinal Chemistry.
28. AMPK Activation through Mitochondrial Regulation Results in Increased Substrate Oxidation and Improved Metabolic Parameters in Models of Diabetes
29. Solid-phase synthesis of highly substituted peptoid 1(2H)-isoquinolinones
30. Solid-phase synthesis of defined 1,4-benzodiazepine-2,5-dione mixtures
31. Enantioselective Synthesis of cis-3-Fluoropiperidin-4-ol, a Building Block for Medicinal Chemistry
32. AMPK activation by a novel small molecule of mitochondrial regulation enhances fatty acid oxidation, ketogenesis and branched chain amino acid catabolism in vivo
33. The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma
34. R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
35. Discovery and Characterization of Substituted Diphenyl Heterocyclic Compounds as Potent and Selective Inhibitors of Hepatitis C Virus Replication
36. R-253 Disrupts Microtubule Networks in Multiple Tumor Cell Lines
37. Global metabolite profiling of mice with high-fat diet-induced obesity chronically treated with AMPK activators R118 or metformin reveals tissue-selective alterations in metabolic pathways.
38. The synthesis of 2-imldazolidones on solid support by tandem aminoacylation/Michael addition
39. A peptoid based synthesis of di- and tri-substituted 2-oxopiperazines on solid support
40. The synthesis of 2-oxopiperazines by intramolecular Michael addition on solid support
41. Chlorophyll-a derivatives in photodynamic therapy: effect of position of heptyl ether side-chains on in vivo photosensitizing activity
42. Discovery of Nanomolar Ligands for 7-Transmembrane G-Protein-Coupled Receptors from a Diverse N-(Substituted)glycine Peptoid Library
43. Enhanced Stability in vitro and in vivo of Immunoconjugates Prepared with 5-Methyl-2-iminothiolane
44. The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma.
45. Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 4. Effect of various side-chain substituents on therapeutic activity against anticholinesterase intoxication
46. Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 5. Structure-activity relationships for side-chain nitro-, sulfone-, amino-, and aminosulfonyl-substituted analogs for therapy against anticholinesterase intoxication
47. Substituted 2-iminothiolanes: reagents for the preparation of disulfide cross-linked conjugates with increased stability
48. N.m.r. Spectra of porphyrins. Part 35. An examination of the proposed models of the chlorophyll a dimer.
49. Bacteriochlorophylls-d from Chlorobium vibrioforme: chromatographic separations and structural assignments of the methyl bacteriopheophorbides.
50. The NMR spectra of porphyrins. 27-proton NMR spectra of chlorophyll- a and pheophytin- a.
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