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5,441 results on '"Goldberg J"'

1. Efficacy and safety of multiple doses of tapentadol oral solution in the treatment of moderate to severe acute pain in children aged 2 to

Author

Beuter C, Volkers G, Radic T, Goldberg J, and van den Anker J

Subjects
tapentadol oral solution, pediatric pain management, moderate to severe acute pain, efficacy, safety, Medicine (General), R5-920
Abstract

Christoph Beuter,1 Gisela Volkers,1 Tatjana Radic,1 Jutta Goldberg,1 John van den Anker2,3 1Grünenthal GmbH, Aachen, Germany; 2Division of Paediatric Pharmacology and Pharmacometrics, University of Basel Children’s Hospital, Basel, Switzerland; 3Division of Clinical Pharmacology, Children’s National Medical Center, Washington, DC, USACorrespondence: Christoph Beuter Grünenthal GmbH, Zieglerstraße 6, 52078 Aachen, GermanyTel +49 241 569 0Email Christoph.Beuter@grunenthal.comBackground: Well-controlled trials of analgesics in the pediatric population are scarce. Tapentadol is a strong centrally acting analgesic which has undergone a pediatric development program investigating its suitability for treating moderate to severe acute pain across the entire pediatric age range from birth to adolescence. Here, we report data from a pivotal Phase III trial performed as part of this development program.Patients and methods: This randomized, double-blind, placebo-controlled, multicenter clinical trial investigated efficacy and safety/tolerability of multiple tapentadol oral solution doses (OS; target dose 1.25 mg/kg) in the treatment of postsurgical acute pain. Data for patients aged 2 to

Published
2019

2. First evaluation of tapentadol oral solution for the treatment of moderate to severe acute pain in children aged 6 to

Author

Finkel JC, Goldberg J, Rosenburg R, Ariyawansa J, Sun T, Ochs-Ross R, Zannikos P, Zhang L, and Etropolski M

Subjects
tapentadol, acute pain, children, µ-opioid, pharmacokinetics, efficacy and safety, Medicine (General), R5-920
Abstract

Julia C Finkel,1 Jutta Goldberg,2 Ronald Rosenburg,2 Jay Ariyawansa,3 Tao Sun,3 Rachel Ochs-Ross,3 Peter Zannikos,3 Liping Zhang,3 Mila Etropolski31Children’s National Medical Center, Washington, DC, USA; 2Grünenthal GmbH, Aachen, Germany; 3Janssen Pharmaceutical, Titusville, NJ, USABackground: This is the first clinical trial in the global pediatric clinical development program for the use of the analgesic tapentadol in children and adolescents.Patients and methods: This multicenter, open-label clinical trial investigated pharmacokinetics, safety and tolerability, and efficacy of tapentadol and its major metabolite tapentadol-O-glucuronide after administration of a single dose of tapentadol oral solution (OS) in pediatric patients aged 6 to

Published
2019

3. Pharmacokinetics, safety, and efficacy of tapentadol oral solution for treating moderate to severe pain in pediatric patients

Author

Muse D, Tarau E, Lefeber C, Sohns M, Brett M, Goldberg J, and Rosenburg R

Subjects
Analgesics, pediatric pain management, moderate to severe pain, opioid receptors, tapentadol, Medicine (General), R5-920
Abstract

Derek Muse,1 Eva Tarau,2 Claudia Lefeber,3 Melanie Sohns,3 Martin Brett,3 Jutta Goldberg,3 Ronald Rosenburg31Jean Brown Research, Salt Lake City, UT, USA; 2Grünenthal USA Inc., Overland Park, KS, USA; 3Grünenthal GmbH, Aachen, GermanyBackground: This trial is part of the global pediatric clinical development program investigating the administration of the strong analgesic tapentadol in children and adolescents.Patients and methods: The single site, open-label phase 2 trial evaluated the pharmacokinetic profile of tapentadol and its major metabolite, tapentadol-O-glucuronide, as well as safety and tolerability and efficacy of a single dose of tapentadol oral solution (1 mg/kg) in patients (2 to

Published
2019

4. Progenitor with small reaction networks should not be used as initial conditions for core collapse

Author

Renzo, M., Goldberg, J. A., Grichener, A., Gottlieb, O., and Cantiello, M.

Subjects
Astrophysics - Solar and Stellar Astrophysics, Astrophysics - High Energy Astrophysical Phenomena
Abstract

Core collapse initial conditions are a bottleneck in understanding the explosion mechanism(s) of massive stars. Stellar evolution codes struggle after carbon burning, and either stop or adopt numerical simplifications missing crucial physics. The use of small nuclear reaction networks (NRN) that account for energy production but bypass weak reactions is typical, but insufficient to study the dynamics of the collapse. We advise against the use of progenitors computed with small NRN in expensive multi-dimensional simulations of core collapse, bounce, (jet formation), and explosion., Comment: accepted by RNAAS, input/output available at https://doi.org/10.5281/zenodo.11375523, code at https://github.com/mathren/CHE_net_comparison

Published
2024

5. Updated constraints on sterile neutrino mixing in the OPERA experiment using a new $\nu_e$ identification method

Author

Agafonova, N., Alexandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bertolin, A., Bozza, C., Brugnera, R., Buontempo, S., Chernyavskiy, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Fini, R. A., Fukuda, T., Galati, G., Garfagnini, A., Gentile, V., Goldberg, J., Gorbunov, S., Gornushkin, Y., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, T., Hollnagel, A., Ishiguro, K., Iuliano, A., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, S. H., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Laudisio, F., Lauria, A., Longhin, A., Loverre, P., Malgin, A., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Miyanishi, M., Mizutani, F., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Niwa, K., Ogawa, S., Okateva, N., Ozaki, K., Paoloni, A., Paparella, L., Park, B. D., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sato, O., Schembri, A., Shakiryanova, I., Shchedrina, T., Shibayama, E., Shibuya, H., Shiraishi, T., Simone, S., Sirignano, C., Sirri, G., Sotnikov, A., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tufanli, S., Vasina, S., Vilain, P., Voevodina, E., Votano, L., Vuilleumier, J. L., Wilquet, G., and Yoon, C. S.

Subjects
High Energy Physics - Experiment
Abstract

This paper describes a new $\nu_e$ identification method specifically designed to improve the low-energy ($< 30\,\mathrm{GeV}$) $\nu_e$ identification efficiency attained by enlarging the emulsion film scanning volume with the next generation emulsion readout system. A relative increase of 25-70% in the $\nu_e$ low-energy region is expected, leading to improvements in the OPERA sensitivity to neutrino oscillations in the framework of the 3 + 1 model. The method is applied to a subset of data where the detection efficiency increase is expected to be more relevant, and one additional $\nu_e$ candidate is found. The analysis combined with the $\nu_\tau$ appearance results improves the upper limit on $\sin^2 2\theta_{\mu e}$ to 0.016 at 90% C.L. in the MiniBooNE allowed region $\Delta m^2_{41} \sim 0.3\,\mathrm{eV}^2$., Comment: 13 pages, 6 figures

Published
2022

6. First observation of a tau neutrino charged current interaction with charm production in the Opera experiment

Author

Agafonova, N., Alexandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bertolin, A., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Chernyavskiy, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Fini, R. A., Fornari, F., Fukuda, T., Galati, G., Garfagnini, A., Gentile, V., Goldberg, J., Gorbunov, S., Gornushkin, Y., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, T., Hollnagel, A., Ishiguro, K., Iuliano, A., ić, K. Jakovč, Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, S. H., Kitagawa, N., ek, B. Klič, Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Laudisio, F., Lauria, A., Longhin, A., Loverre, P., Malgin, A., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Miyanishi, M., Mizutani, F., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Niwa, K., Ogawa, S., Okateva, N., Ozaki, K., Paoloni, A., Paparella, L., Park, B. D., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sato, O., Schembri, A., Shakiryanova, I., Shchedrina, T., Shibayama, E., Shibuya, H., Shiraishi, T., Simone, S., Sirignano, C., Sirri, G., Sotnikov, A., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., ević, M. Stipč, Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Vasina, S., Vilain, P., Voevodina, E., Votano, L., Vuilleumier, J. L., Wilquet, G., and Yoon, C. S.

Subjects
High Energy Physics - Experiment
Abstract

An event topology with two secondary vertices compatible with the decay of short-lived particles was found in the analysis of neutrino interactions in the Opera target. The observed topology is compatible with tau neutrino charged current (CC) interactions with charm production and neutrino neutral current (NC) interactions with $c\overline{c}$ pair production. However, other processes can mimic this topology. A dedicated analysis was implemented to identify the underlying process. A Monte Carlo simulation was developed and complementary procedures were introduced in the kinematic reconstruction. A multivariate analysis technique was used to achieve an optimal separation of signal from background. Most likely, this event is a $\nu_{\tau}$ CC interaction with charm production, the tau and charm particle decaying into 1 prong and 2 prongs, respectively. The significance of this observation is evaluated., Comment: 10 pages, 7 figures; Editors: Marco Roda, Chiara Sirignano and Gabriele Sirri

Published
2019
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7. Final results on neutrino oscillation parameters from the OPERA experiment in the CNGS beam

Author

OPERA Collaboration, Agafonova, N., Alexandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bertolin, A., Bozza, C., Brugnera, R., Buontempo, S., Chernyavskiy, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Fini, R. A., Fukuda, T., Galati, G., Garfagnini, A., Gentile, V., Goldberg, J., Gorbunov, S., Gornushkin, Y., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, T., Hollnagel, A., Ishiguro, K., Iuliano, A., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, S. H., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Laudisio, F., Lauria, A., Longhin, A., Loverre, P., Malgin, A., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Miyanishi, M., Mizutani, F., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Niwa, K., Ogawa, S., Okateva, N., Ozaki, K., Paoloni, A., Paparella, L., Park, B. D., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sato, O., Schembri, A., Shakiryanova, I., Shchedrina, T., Shibayama, E., Shibuya, H., Shiraishi, T., Simone, S., Sirignano, C., Sirri, G., Sotnikov, A., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tufanli, S., Vasina, S., Vilain, P., Voevodina, E., Votano, L., Vuilleumier, J. L., Wilquet, G., and Yoon, C. S.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

The OPERA experiment has conclusively observed the appearance of tau neutrinos in the muon neutrino CNGS beam. Exploiting the OPERA detector capabilities, it was possible to isolate high purity samples of $\nu_{e}$, $\nu_{\mu}$ and $\nu_{\tau}$ charged current weak neutrino interactions, as well as neutral current weak interactions. In this Letter, the full dataset is used for the first time to test the three-flavor neutrino oscillation model and to derive constraints on the existence of a light sterile neutrino within the framework of the $3+1$ neutrino model. For the first time, tau and electron neutrino appearance channels are jointly used to test the sterile neutrino hypothesis. A significant fraction of the sterile neutrino parameter space allowed by LSND and MiniBooNE experiments is excluded at 90% C.L. In particular, the best-fit values obtained by MiniBooNE combining neutrino and antineutrino data are excluded at 3.3 $\sigma$ significance., Comment: 7 pages, 4 figures; Editors: Budimir Kli\v{c}ek and Matteo Tenti

Published
2019
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10. Latest results of the OPERA experiment on nu-tau appearance in the CNGS neutrino beam

Author

Agafonova, N., Alexandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bertolin, A., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Chernyavskiy, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Favier, J., Fini, R. A., Fornari, F., Fukuda, T., Galati, G., Garfagnini, A., Gentile, V., Goldberg, J., Gorbunov, S., Gornushkin, Y., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, T., Hollnagel, A., Ishiguro, K., Iuliano, A., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, S. H., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Laudisio, F., Lauria, A., Longhin, A., Loverre, P., Malenica, M., Malgin, A., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Miyanishi, M., Mizutani, F., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Niwa, K., Ogawa, S., Olchevsky, A., Okateva, N., Ozaki, K., Paoloni, A., Paparella, L., Park, B. D., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Pistillo, C., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sadovsky, A., Sato, O., Schembri, A., Shakiryanova, I., Shchedrina, T., Shibayama, E., Shibuya, H., Shiraishi, T., Simone, S., Sirignano, C., Sirri, G., Sotnikov, A., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tufanli, S., Ustyuzhanin, A., Vasina, S., Vilain, P., Voevodina, E., Votano, L., Vuilleumier, J. L., Wilquet, G., Wonsak, B., and Yoon, C. S.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

OPERA is a long-baseline experiment designed to search for $\nu_{\mu}\to\nu_{\tau}$ oscillations in appearance mode. It was based at the INFN Gran Sasso laboratory (LNGS) and took data from 2008 to 2012 with the CNGS neutrino beam from CERN. After the discovery of $\nu_\tau$ appearance in 2015, with $5.1\sigma$ significance, the criteria to select $\nu_\tau$ candidates have been extended and a multivariate approach has been used for events identification. In this way the statistical uncertainty in the measurement of the oscillation parameters and of $\nu_\tau$ properties has been improved. Results are reported., Comment: 7 pages, 1 figure, conference: The 15th International Workshop on Tau Lepton Physics (tau2018)AB

Published
2018

11. Measurement of the cosmic ray muon flux seasonal variation with the OPERA detector

Author

Agafonova, N., Alexandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bertolin, A., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Chernyavskiy, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Fini, R. A., Fornari, F., Fukuda, T., Galati, G., Garfagnini, A., Gentile, V., Goldberg, J., Gorbunov, S., Gornushkin, Y., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, T., Hollnagel, A., Ishiguro, K., Iuliano, A., Jakovčić, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, S. H., Kitagawa, N., Kliček, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Laudisio, F., Lauria, A., Ljubičić, A., Longhin, A., Loverre, P., Malgin, A., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Miyanishi, M., Mizutani, F., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Niwa, K., Ogawa, S., Okateva, N., Ozaki, K., Paoloni, A., Paparella, L., Park, B. D., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sato, O., Schembri, A., Shakiryanova, I., Shchedrina, T., Shibayama, E., Shibuya, H., Shiraishi, T., Simone, S., Sirignano, C., Sirri, G., Sotnikov, A., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipčević, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Vasina, S., Vilain, P., Voevodina, E., Votano, L., Vuilleumier, J. L., Wilquet, G., and Yoon, C. S.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

The OPERA experiment discovered muon neutrino into tau neutrino oscillations in appearance mode, detecting tau leptons by means of nuclear emulsion films. The apparatus was also endowed with electronic detectors with tracking capability, such as scintillator strips and resistive plate chambers. Because of its location, in the underground Gran Sasso laboratory, under 3800 m.w.e., the OPERA detector has also been used as an observatory for TeV muons produced by cosmic rays in the atmosphere. In this paper the measurement of the single muon flux modulation and of its correlation with the seasonal variation of the atmospheric temperature are reported.

Published
2018
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12. Final results of the OPERA experiment on $\nu_\tau$ appearance in the CNGS beam

Author

OPERA Collaboration, Agafonova, N., Alexandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bertolin, A., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Chernyavskiy, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Favier, J., Fini, R. A., Fornari, F., Fukuda, T., Galati, G., Garfagnini, A., Gentile, V., Goldberg, J., Gornushkin, Y., Gorbunov, S., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, T., Hollnagel, A., Ishiguro, K., Iuliano, A., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, S. H., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Laudisio, F., Lauria, A., Ljubicic, A., Longhin, A., Loverre, P., Malgin, A., Malenica, M., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Miyanishi, M., Mizutani, F., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Niwa, K., Okateva, N., Olchevsky, A., Ogawa, S., Ozaki, K., Paoloni, A., Paparella, L., Park, B. D., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Pistillo, C., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sadovsky, A., Sato, O., Schembri, A., Shakiryanova, I., Shchedrina, T., Shibuya, H., Shibayama, E., Shiraishi, T., Simone, S., Sirignano, C., Sirri, G., Sotnikov, A., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tufanli, S., Ustyuzhanin, A., Vasina, S., Vilain, P., Voevodina, E., Votano, L., Vuilleumier, J. L., Wilquet, G., Wonsak, B., and Yoon, C. S.

Subjects
High Energy Physics - Experiment
Abstract

The OPERA experiment was designed to study $\nu_\mu\to\nu_\tau$ oscillations in appearance mode in the CNGS neutrino beam. In this letter we report the final analysis of the full data sample collected between 2008 and 2012, corresponding to $17.97\cdot 10^{19}$ protons on target. Selection criteria looser than in previous analyses have produced ten $\nu_\tau$ candidate events, thus reducing the statistical uncertainty in the measurement of the oscillation parameters and of $\nu_\tau$ properties. A multivariate approach for event identification has been applied to the candidate events and the discovery of $\nu_\tau$ appearance is confirmed with an improved significance level of 6.1 $\sigma$. $\Delta m^2_{23}$ has been measured, in appearance mode, with an accuracy of 20%. The measurement of $\nu_\tau$ CC cross-section, for the first time with a negligible contamination from $\bar{\nu}_\tau$, and the first direct observation of the $\nu_\tau$ lepton number are also reported., Comment: 7 pages, 3 figures

Published
2018
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13. Final results of the search for $\nu_{\mu} \to \nu_{e}$ oscillations with the OPERA detector in the CNGS beam

Author

OPERA Collaboration, Agafonova, N., Aleksandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bertolin, A., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Chernyavskiy, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Favier, J., Fini, R. A., Fornari, F., Fukuda, T., Galati, G., Garfagnini, A., Gentile, V., Goldberg, J., Gornushkin, Y., Gorbunov, S., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, T., Hollnagel, A., Hosseini, B., Ishiguro, K., Iuliano, A., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, S. H., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Laudisio, F., Lauria, A., Ljubicic, A., Longhin, A., Loverre, P., Malgin, A., Malenica, M., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meisel, F., Meregaglia, A., Mikado, S., Miyanishi, M., Mizutani, F., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Niwa, K., Okateva, N., Ogawa, S., Ozaki, K., Paoloni, A., Paparella, L., Park, B. D., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sato, O., Schembri, A., Shakiryanova, I., Shchedrina, T., Shibuya, H., Shibayama, E., Shiraishi, T., Simone, S., Sirignano, C., Sirri, G., Sotnikov, A., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Vasina, S., Vilain, P., Voevodina, E., Votano, L., Vuilleumier, J. L., Wilquet, G., and Yoon, C. S.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

The OPERA experiment has discovered the tau neutrino appearance in the CNGS muon neutrino beam, in agreement with the 3 neutrino flavour oscillation hypothesis. The OPERA neutrino interaction target, made of Emulsion Cloud Chamber, was particularly efficient in the reconstruction of electromagnetic showers. Moreover, thanks to the very high granularity of the emulsion films, showers induced by electrons can be distinguished from those induced by $\pi^0$s, thus allowing the detection of charged current interactions of electron neutrinos. In this paper the results of the search for electron neutrino events using the full dataset are reported. An improved method for the electron neutrino energy estimation is exploited. Data are compatible with the 3 neutrino flavour mixing model expectations and are used to set limits on the oscillation parameters of the 3+1 neutrino mixing model, in which an additional mass eigenstate $m_{4}$ is introduced. At high $\Delta m^{2}_{41}$ $( \gtrsim 0.1~\textrm{eV}^{2})$, an upper limit on $\sin^2 2\theta_{\mu e}$ is set to 0.021 at 90% C.L. and $\Delta m^2_{41} \gtrsim 4 \times 10^{-3}~\textrm{eV}^{2}$ is excluded for maximal mixing in appearance mode., Comment: Editors: M. Tenti and S. Vasina

Published
2018

14. Living in a predictable environment: Intraspecific variation in tadpole size and shape of the Sierra's treefrog.

Author

Bonino, A., Lescano, J., Goldberg, J., and Quinzio, S. I.

Abstract

Within the breeding sites of anurans, factors at the microhabitat scale can exhibit variations over the years, resulting in temporal fluctuations within these sites. These fluctuations may lead to modifications in "normal larval development" and observable phenotypic changes. These developmental alterations appear to have evolved as shared strategies for achieving reproductive success and ensuring the survival of offspring. In a population of Boana cordobae inhabiting the Central Pampean Sierras (Córdoba, Argentina), the coexistence of pre‐ and prometamorphic tadpoles throughout the year, coupled with variations in size and shape within the same developmental stage, has led us to question about the duration of the larval period, variations in the timing of developmental events, and the possible existence of distinct larval morphs for this species. Utilizing data collected over four consecutive years from various locations, we described the development, growth, and larval morphology using both linear and geometric morphometrics during the pre‐ and prometamorphic stages. Our aim was to comprehend how anuran larvae in predictable environments synchronize the timing of their phenotypic transformations with external conditions. We identified two distinct cohorts: spring–summer and autumn–spring, each exhibiting distinct rates of growth and development until metamorphosis, resulting in size discrepancies. Moreover, the physical attributes of the breeding sites influenced the size of the tadpoles. However, the observed variation in shape was not related to the ontogenetic period, cohort, or developmental site. Ultimately, the observed variations had no impact on the morphology at metamorphosis. The comprehensive data gathered from our observations in B. cordobae yield valuable insights that contribute to a deeper comprehension of anuran larval development under natural conditions where changes are predictable and follow a regular pattern throughout the year, ultimately maximizing reproductive success. [ABSTRACT FROM AUTHOR]

Published
2024
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17. A Multi-Smartwatch System for Assessing Speech Characteristics of People with Dysarthria in Group Settings

Author

Dubey, Harishchandra, Goldberg, J. Cody, Mankodiya, Kunal, and Mahler, Leslie

Subjects
Computer Science - Computers and Society, Computer Science - Sound
Abstract

Speech-language pathologists (SLPs) frequently use vocal exercises in the treatment of patients with speech disorders. Patients receive treatment in a clinical setting and need to practice outside of the clinical setting to generalize speech goals to functional communication. In this paper, we describe the development of technology that captures mixed speech signals in a group setting and allows the SLP to analyze the speech signals relative to treatment goals. The mixed speech signals are blindly separated into individual signals that are preprocessed before computation of loudness, pitch, shimmer, jitter, semitone standard deviation and sharpness. The proposed method has been previously validated on data obtained from clinical trials of people with Parkinson disease and healthy controls., Comment: 6 page, 9 figure, 1 table, 8 equations, Proceedings e-Health Networking, Applications and Services (Healthcom), 2015 IEEE 17th International Conference on, Boston, USA. 2015

Published
2016
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18. Discovery of tau neutrino appearance in the CNGS neutrino beam with the OPERA experiment

Author

OPERA Collaboration, Agafonova, N., Aleksandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bender, D., Bertolin, A., Bodnarchuk, I., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Büttner, B., Chernyavsky, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. Del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievski, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Fini, R. A., Fornari, F., Fukuda, T., Galati, G., Garfagnini, A., Goldberg, J., Gornushkin, Y., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, H., Hollnagel, A., Hosseini, B., Ishiguro, K., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, J. H., Kim, S. H., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Laudisio, F., Lauria, A., Ljubicic, A., Longhin, A., Loverre, P. F., Malgin, A., Malenica, M., Mandrioli, G., Matsuo, T., Matsushita, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Miyanishi, M., Mizutani, F., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Nakatsuka, Y., Niwa, K., Ogawa, S., Olchevsky, A., Omura, T., Ozaki, K., Paoloni, A., Paparella, L., Park, B. D., Park, I. G., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Pistillo, C., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sato, O., Schembri, A., Schmidt-Parzefall, W., Shakirianova, I., Shchedrina, T., Sheshukov, A., Shibuya, H., Shiraishi, T., Shoziyoev, G., Simone, S., Sioli, M., Sirignano, C., Sirri, G., Sotnikov, A., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tufanli, S., Vilain, P., Vladymyrov, M., Votano, L., Vuilleumier, J. L., Wilquet, G., Wonsak, B., Yoon, C. S., and Zemskova, S.

Subjects
High Energy Physics - Experiment
Abstract

The OPERA experiment was designed to search for $\nu_{\mu} \rightarrow \nu_{\tau}$ oscillations in appearance mode, i.e. by detecting the $\tau$-leptons produced in charged current $\nu_{\tau}$ interactions. The experiment took data from 2008 to 2012 in the CERN Neutrinos to Gran Sasso beam. The observation of $\nu_{\mu} \rightarrow \nu_{\tau}$ appearance, achieved with four candidate events in a sub-sample of the data, was previously reported. In this paper, a fifth $\nu_{\tau}$ candidate event, found in an enlarged data sample, is described. Together with a further reduction of the expected background, the candidate events detected so far allow assessing the discovery of $\nu_{\mu}\rightarrow \nu_{\tau}$ oscillations in appearance mode with a significance larger than 5 $\sigma$., Comment: 7 pages, 3 figures

Published
2015
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19. Limits on muon-neutrino to tau-neutrino oscillations induced by a sterile neutrino state obtained by OPERA at the CNGS beam

Author

OPERA Collaboration, Agafonova, N., Aleksandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bender, D., Bertolin, A., Bodnarchuk, I., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Büttner, B., Chernyavsky, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. Del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievski, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Fini, R. A., Fukuda, T., Galati, G., Garfagnini, A., Goldberg, J., Gornushkin, Y., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hollnagel, A., Hosseini, B., Ishiguro, K., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, J. H., Kim, S. H., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Lauria, A., Ljubicic, A., Longhin, A., Malgin, A., Malenica, M., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Nakatsuka, Y., Niwa, K., Ogawa, S., Omura, T., Ozaki, K., Paoloni, A., Paparella, L., Park, B. D., Park, I. G., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sato, O., Schembri, A., Shakirianova, I., Shchedrina, T., Sheshukov, A., Shibuya, H., Shiraishi, T., Shoziyoev, G., Simone, S., Sioli, M., Sirignano, C., Sirri, G., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tufanli, S., Vilain, P., Vladymyrov, M., Votano, L., Vuilleumier, J. L., Wilquet, G., Wonsak, B., Yoon, C. S., and Zemskova, S.

Subjects
High Energy Physics - Experiment
Abstract

The OPERA experiment, exposed to the CERN to Gran Sasso $\nu_\mu$ beam, collected data from 2008 to 2012. Four oscillated $\nu_\tau$ Charged Current interaction candidates have been detected in appearance mode, which are consistent with $\nu_\mu \to \nu_\tau$ oscillations at the atmospheric $\Delta m^2$ within the "standard" three-neutrino framework. In this paper, the OPERA $\nu_\tau$ appearance results are used to derive limits on the mixing parameters of a massive sterile neutrino., Comment: 11 pages, 4 figures; reference to Planck result updated in the Introduction. Submitted to JHEP

Published
2015
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21. Observation of nu_tau appearance in the CNGS beam with the OPERA experiment

Author

OPERA Collaboration, Agafonova, N., Aleksandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Asada, T., Bender, D., Bertolin, A., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Buttne, B., Chernyavsky, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. Del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievski, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Fini, R. A., Fukuda, T., Galati, G., Garfagnini, A., Giacomelli, G., Goellnitz, C., Goldberg, J., Gornushkin, Y., Grella, G., Guler, M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, T., Hollnagel, A., Hosseini, B., Ishida, H., Ishiguro, K., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Katsuragawa, T., Kawada, J., Kawahara, H., Kim, J. H., Kim, S. H., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Lauria, A., Lenkeit, J., Ljubicic, A., Longhin, A., Loverre, P., Malenica, M., Malgin, A., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Meyer, M., Mikado, S., Miyanishi, M., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Nakatsuka, Y., Niwa, K., Ogawa, S., Okateva, N., Olshevsky, A., Omura, T., Ozaki, K., Paoloni, A., Park, B. D., Park, I. G., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Pistillo, C., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sato, O., Schembri, A., Shakiryanova, I., Shchedrina, T., Sheshukov, A., Shibuya, H., Shiraishi, T., Shoziyoev, G., Simone, S., Sioli, M., Sirignano, C., Sirri, G., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tufanli, S., Umemoto, A., Vilain, P., Vladimirov, M., Votano, L., Vuilleumier, J. L., Wilquet, G., Wonsak, B., Yoon, C. S., Yaguchi, I., Yoshimoto, M., Zemskova, S., and Zghiche, A.

Subjects
High Energy Physics - Experiment
Abstract

The OPERA experiment is searching for nu_mu -> nu_tau oscillations in appearance mode i.e. via the direct detection of tau leptons in nu_tau charged current interactions. The evidence of nu_mu -> nu_tau appearance has been previously reported with three nu_tau candidate events using a sub-sample of data from the 2008-2012 runs. We report here a fourth nu_tau candidate event, with the tau decaying into a hadron, found after adding the 2012 run events without any muon in the final state to the data sample. Given the number of analysed events and the low background, nu_mu -> nu_tau oscillations are established with a significance of 4.2sigma., Comment: Submitted to Progress of Theoretical and Experimental Physics (PTEP)

Published
2014
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22. Determination of the muon charge sign with the dipolar spectrometers of the OPERA experiment

Author

OPERA Collaboration, Agafonova, N., Aleksandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bender, D., Bertolin, A., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Büttner, B., Chernyavsky, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. Del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievski, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Fini, R. A., Fukuda, T., Galati, G., Garfagnini, A., Giacomelli, G., Goellnitz, C., Goldberg, J., Goloubkov, D., Gornushkin, Y., Grella, G., Guler, M., Gustavino, C., Hagner, C., Hara, T., Hollnagel, A., Hosseini, B., Ishida, H., Ishiguro, K., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kawada, J., Kim, J. H., Kim, S. H., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Lauria, A., Lenkeit, J., Ljubicic, A., Longhin, A., Loverre, P., Malgin, A., Malenica, M., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Meyer, M., Mikado, S., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Nakatsuka, Y., Niwa, K., Ogawa, S., Okateva, N., Olshevsky, A., Omura, T., Ozaki, K., Paoloni, A., Park, B. D., Park, I. G., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Pistillo, C., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Rokujo, H., Roganova, T., Rosa, G., Rostovtseva, I., Ryazhskaya, O., Sato, O., Sato, Y., Schembri, A., Shakiryanova, I., Shchedrina, T., Sheshukov, A., Shibuya, H., Shiraishi, T., Shoziyoev, G., Simone, S., Sioli, M., Sirignano, C., Sirri, G., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tufanli, S., Vilain, P., Vladimirov, M., Votano, L., Vuilleumier, J. L., Wilquet, G., Wonsak, B., Yoon, C. S., Zaitsev, Y., Zemskova, S., and Zghiche, A.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

The OPERA long-baseline neutrino-oscillation experiment has observed the direct appearance of $\nu_\tau$ in the CNGS $\nu_\mu$ beam. Two large muon magnetic spectrometers are used to identify muons produced in the $\tau$ leptonic decay and in $\nu_\mu^{CC}$ interactions by measuring their charge and momentum. Besides the kinematic analysis of the $\tau$ decays, background resulting from the decay of charmed particles produced in $\nu_\mu^{CC}$ interactions is reduced by efficiently identifying the muon track. A new method for the charge sign determination has been applied, via a weighted angular matching of the straight track-segments reconstructed in the different parts of the dipole magnets. Results obtained for Monte Carlo and real data are presented. Comparison with a method where no matching is used shows a significant reduction of up to 40\% of the fraction of wrongly determined charges., Comment: 10 pages. Improvements in the text

Published
2014

23. Procedure for short-lived particle detection in the OPERA experiment and its application to charm decays

Author

Agafonova, N., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bender, D., Bertolin, A., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Buttner, B., Chernyavsky, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. Del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievski, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Fini, R. A., Fukuda, T., Galati, G., Garfagnini, A., Giacomelli, G., Gollnitz, C., Goldberg, J., Gornushkin, Y., Grella, G., Guler, M., Gustavino, C., Hagner, C., Hara, T., Hollnagel, A., Hosseini, B., Ishida, H., Ishiguro, K., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kawada, J., Kim, J. H., Kim, S. H., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Lauria, A., Lenkeit, J., Ljubicic, A., Longhin, A., Loverre, P., Malgin, A., Malenica, M., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Nakatsuka, Y., Niwa, K., Ogawa, S., Okateva, N., Olshevsky, A., Omura, T., Ozaki, K., Paoloni, A., Park, B. D., Park, I. G., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Pistillo, C., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Rokujo, H., Roganova, T., Rosa, G., Ryazhskaya, O., Sato, O., Schembri, A., Shakiryanova, I., Shchedrina, T., Sheshukov, A., Shibuya, H., Shiraishi, T., Shoziyoev, G., Simone, S., Sioli, M., Sirignano, C., Sirri, G., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strauss, T., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tufanli, S., Vilain, P., Vladimirov, M., Votano, L., Vuilleumier, J. L., Wilquet, G., Wonsak, B., Yoon, C. S., Zemskova, S., and Zghiche, A.

Subjects
High Energy Physics - Experiment
Abstract

The OPERA experiment, designed to perform the first observation of $\nu_\mu \rightarrow \nu_\tau$ oscillations in appearance mode through the detection of the $\tau$ leptons produced in $\nu_\tau$ charged current interactions, has collected data from 2008 to 2012. In the present paper, the procedure developed to detect $\tau$ particle decays, occurring over distances of the order of 1 mm from the neutrino interaction point, is described in detail. The results of its application to the search for charmed hadrons are then presented as a validation of the methods for $\nu_\tau$ appearance detection.

Published
2014
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24. Measurement of TeV atmospheric muon charge ratio with the full OPERA data

Author

Agafonova, N., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bender, D., Bertolin, A., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Buettner, B., Chernyavsky, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. Del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievski, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Fini, R. A., Fukuda, T., Galati, G., Garfagnini, A., Giacomelli, G., Goellnitz, C., Goldberg, J., Gornushkin, Y., Grella, G., Guler, M., Gustavino, C., Hagner, C., Hara, T., Hollnagel, A., Hosseini, B., Ishida, H., Ishiguro, K., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kawada, J., Kim, J. H., Kim, S. H., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Lauria, A., Lenkeit, J., Ljubicic, A., Longhin, A., Loverre, P., Malgin, A., Malenica, M., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Nakatsuka, Y., Niwa, K., Ogawa, S., Okateva, N., Olshevsky, A., Omura, T., Ozaki, K., Paoloni, A., Park, B. D., Park, I. G., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Pistillo, C., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Rokujo, H., Roganova, T., Rosa, G., Ryazhskaya, O., Sato, O., Schembri, A., Shakiryanova, I., Shchedrina, T., Sheshukov, A., Shibuya, H., Shiraishi, T., Shoziyoev, G., Simone, S., Sioli, M., Sirignano, C., Sirri, G., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tufanli, S., Vilain, P., Vladimirov, M., Votano, L., Vuilleumier, J. L., Wilquet, G., Wonsak, B., Yoon, C. S., Zemskova, S., and Zghiche, A.

Subjects
High Energy Physics - Experiment
Abstract

The OPERA detector, designed to search for $\nu_{\mu} \to \nu_{\tau}$ oscillations in the CNGS beam, is located in the underground Gran Sasso laboratory, a privileged location to study TeV-scale cosmic rays. For the analysis here presented, the detector was used to measure the atmospheric muon charge ratio in the TeV region. OPERA collected charge-separated cosmic ray data between 2008 and 2012. More than 3 million atmospheric muon events were detected and reconstructed, among which about 110000 multiple muon bundles. The charge ratio $R_{\mu} \equiv N_{\mu^+}/N_{\mu^-}$ was measured separately for single and for multiple muon events. The analysis exploited the inversion of the magnet polarity which was performed on purpose during the 2012 Run. The combination of the two data sets with opposite magnet polarities allowed minimizing systematic uncertainties and reaching an accurate determination of the muon charge ratio. Data were fitted to obtain relevant parameters on the composition of primary cosmic rays and the associated kaon production in the forward fragmentation region. In the surface energy range 1-20 TeV investigated by OPERA, $R_{\mu}$ is well described by a parametric model including only pion and kaon contributions to the muon flux, showing no significant contribution of the prompt component. The energy independence supports the validity of Feynman scaling in the fragmentation region up to $200$ TeV/nucleon primary energy., Comment: 8 pages, 2 figures, 4 tables

Published
2014
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25. Evidence for $\nu_\mu \to \nu_\tau$ appearance in the CNGS neutrino beam with the OPERA experiment

Author

Agafonova, N., Aleksandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Asada, T., Autiero, D., Dhahbi, A. Ben, Badertscher, A., Bender, D., Bertolin, A., Bozza, C., Brugnera, R., Brunet, F., Brunetti, G., Buonaura, A., Buontempo, S., Buettner, B., Chaussard, L., Chernyavsky, M., Chiarella, V., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. Del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievski, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Favier, J., Ferber, T., Ferone, G., Fini, R. A., Fukuda, T., Galati, G., Garfagnini, A., Giacomelli, G., Goellnitz, C., Goldberg, J., Gornushkin, Y., Grella, G., Grianti, F., Guler, M., Gustavino, C., Hagner, C., Hakamata, K., Hara, T., Hayakawa, T., Hierholzer, M., Hollnagel, A., Hosseini, B., Ishida, H., Ishiguro, K., Ishikawa, M., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Katsuragawa, T., Kawada, J., Kawahara, H., Kim, J. H., Kim, S. H., Kimura, M., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Lauria, A., Lenkeit, J., Ljubicic, A., Longhin, A., Loverre, P., Malgin, A., Mandrioli, G., Marteau, J., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Migliozzi, P., Mikado, S., Miyanishi, M., Miyashita, E., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Nakatsuka, Y., Niwa, K., Ogawa, S., Okateva, N., Olshevsky, A., Omura, T., Ozaki, K., Paoloni, A., Park, B. D., Park, I. G., Pastore, A., Patrizii, L., Pennacchio, E., Pessard, H., Pistillo, C., Podgrudkov, D., Polukhina, N., Pozzato, M., Pretzl, K., Pupilli, F., Rescigno, R., Roda, M., Rokujo, H., Roganova, T., Rosa, G., Rostovtseva, I., Rubbia, A., Ryazhskaya, O., Sato, O., Sato, Y., Schembri, A., Schmidt-Parzefal, W., Shakiryanova, I., Shchedrina, T., Sheshukov, A., Shibuya, H., Shiraishi, T., Shoziyoev, G., Simone, S., Sioli, M., Sirignano, C., Sirri, G., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strauss, T., Strolin, P., Suzuki, K., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tufanli, S., Vilain, P., Vladimirov, M., Votano, L., Vuilleumier, J. L., Wilquet, G., Wonsak, B., Yoon, C. S., Yoshida, J., Yoshimoto, M., Zaitsev, Y., Zemskova, S., and Zghiche, A.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

The OPERA experiment is designed to search for $\nu_{\mu} \rightarrow \nu_{\tau}$ oscillations in appearance mode i.e. through the direct observation of the $\tau$ lepton in $\nu_{\tau}$ charged current interactions. The experiment has taken data for five years, since 2008, with the CERN Neutrino to Gran Sasso beam. Previously, two $\nu_{\tau}$ candidates with a $\tau$ decaying into hadrons were observed in a sub-sample of data of the 2008-2011 runs. Here we report the observation of a third $\nu_\tau$ candidate in the $\tau^-\to\mu^-$ decay channel coming from the analysis of a sub-sample of the 2012 run. Taking into account the estimated background, the absence of $\nu_{\mu} \rightarrow \nu_{\tau}$ oscillations is excluded at the 3.4 $\sigma$ level., Comment: 9 pages, 5 figures, 1 tables

Published
2014
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27. OPERA tau neutrino charged current interactions

Author

Agafonova, N., Alexandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bertolin, A., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Chernyavskiy, M., Chukanov, A., Consiglio, L., D’Ambrosio, N., De Lellis, G., De Serio, M., del Amo Sanchez, P., Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Fini, R. A., Fornari, F., Fukuda, T., Galati, G., Garfagnini, A., Gentile, V., Goldberg, J., Gorbunov, S., Gornushkin, Y., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, T., Hollnagel, A., Ishiguro, K., Iuliano, A., Jakovčić, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, S. H., Kitagawa, N., Kliček, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Laudisio, F., Lauria, A., Lavasa, A., Longhin, A., Loverre, P., Malgin, A., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Miyanishi, M., Mizutani, F., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Niwa, K., Ogawa, S., Okateva, N., Ozaki, K., Paoloni, A., Park, B. D., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sato, O., Shakirianova, I., Schembri, A., Shchedrina, T., Shibayama, E., Shibuya, H., Shiraishi, T., Šimko, T., Simone, S., Sirignano, C., Sirri, G., Sotnikov, A., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipčević, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tsanaktsidis, I., Tufanli, S., Ustyuzhanin, A., Vasina, S., Vidal García, M., Vilain, P., Voevodina, E., Votano, L., Vuilleumier, J. L., Wilquet, G., and Yoon, C. S.

Published
2021
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28. New results on $\nu_\mu \to \nu_\tau$ appearance with the OPERA experiment in the CNGS beam

Author

OPERA Collaboration, Agafonova, N., Aleksandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Asada, T., Autiero, D., Badertscher, A., Dhahbi, A. Ben, Bender, D., Bertolin, A., Bozza, C., Brugnera, R., Brunetti, G., Buettner, B., Buontempo, S., Chaussard, L., Chernyavskiy, M., Chiarella, V., Chukanov, A., Consiglio, L., D'Ambrosio, N., Sanchez, P. Del Amo, De Lellis, G., De Serio, M., Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievski, S., Dracos, M., Duchesneau, D., Dusini, S., Ebert, J., Ereditato, A., Favier, J., Ferber, T., Fini, R. A., Fukuda, T., Garfagnini, A., Giacomelli, G., Goellnitz, C., Goldberg, J., Gornushkin, Y., Grella, G., Grianti, F., Guler, A. M., Gustavino, C., Hagner, C., Hakamata, K., Hara, T., Hayakawa, T., Hierholzer, M., Hollnagel, A., Hosseini, B., Ishida, H., Ishiguro, K., Ishikawa, M., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Katsuragawa, T., Kawahara, H., Kawada, J., Kim, J. H., Kim, S. H., Kimura, M., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Lauria, A., Lenkeit, J., Ljubicic, A., Longhin, A., Loverre, P., Malgin, A., Mandrioli, G., Marteau, J., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Migliozzi, P., Mikado, S., Minotti, A., Miyanishi, M., Miyashita, E., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Nakatsuka, Y., Niwa, K., Ogawa, S., Okateva, N., Olshevsky, A., Omura, T., Ozaki, K., Paoloni, A., Park, B. D., Park, I. G., Pastore, A., Patrizii, L., Pennacchio, E., Pessard, H., Pistillo, C., Podgrudkov, D., Polukhina, N., Pozzato, M., Pretzl, K., Pupilli, F., Rescigno, R., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Rostovtseva, I., Rubbia, A., Russo, A., Ryazhskaya, O., Sato, O., Sato, Y., Schembri, A., Schmidt-Parzefall, W., Shakiryanova, I., Schcedrina, T., Sheshukov, A., Shibuya, H., Shiraishi, T., Shoziyoev, G., Simone, S., Sioli, M., Sirignano, C., Sirri, G., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strauss, T., Strolin, P., Suzuki, K., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tolun, P., Tufanli, S., Vilain, P., Vladimirov, M., Votano, L., Vuilleumier, J. L., Wilquet, G., Wonsak, B., Yoon, C. S., Yoshida, J., Yoshimoto, M., Zaitsev, Y., Zemskova, S., and Zghiche, A.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

The OPERA neutrino experiment is designed to perform the first observation of neutrino oscillations in direct appearance mode in the $\nu_\mu \to \nu_\tau$ channel, via the detection of the $\tau$-leptons created in charged current $\nu_\tau$ interactions. The detector, located in the underground Gran Sasso Laboratory, consists of an emulsion/lead target with an average mass of about 1.2 kt, complemented by electronic detectors. It is exposed to the CERN Neutrinos to Gran Sasso beam, with a baseline of 730 km and a mean energy of 17 GeV. The observation of the first $\nu_\tau$ candidate event and the analysis of the 2008-2009 neutrino sample have been reported in previous publications. This work describes substantial improvements in the analysis and in the evaluation of the detection efficiencies and backgrounds using new simulation tools. The analysis is extended to a sub-sample of 2010 and 2011 data, resulting from an electronic detector-based pre-selection, in which an additional $\nu_\tau$ candidate has been observed. The significance of the two events in terms of a $\nu_\mu \to \nu_\tau$ oscillation signal is of 2.40 $\sigma$., Comment: 33 pages, 12 figures, 5 tables. Prepared for submission to JHEP

Published
2013

29. Search for $\nu_\mu \rightarrow \nu_e$ oscillations with the OPERA experiment in the CNGS beam

Author

OPERA collaboration, Agafonova, N., Aleksandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Autiero, D., Badertscher, A., Dhahbi, A. Ben, Bertolin, A., Bozza, C., Brugnera, R., Brunet, F., Brunetti, G., Buettner, B., Buontempo, S., Chaussard, L., Chernyavsky, M., Chiarella, V., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Ferber, T., Fini, R. A., Fukuda, T., Garfagnini, A., Giacomelli, G., Goellnitz, C., Goldberg, J., Gornushkin, Y., Grella, G., Grianti, F., Guler, A. M., Gustavino, C., Hagner, C., Hamada, K., Hara, T., Hierholzer, M., Hollnagel, A., Hosseini, B., Ishida, H., Ishiguro, K., Jakovcic, K., Jollet, C., Juget, F., Kamiscioglu, C., Kamiscioglu, M., Kawada, J., Kim, J. H., Kim, S. H., Kimura, M., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Lauria, A., Lenkeit, J., Ljubicic, A., Longhin, A., Loverre, P., Malgin, A., Mancini-Terracciano, C., Mandrioli, G., Marteau, J., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meisel, F. W., Meregaglia, A., Migliozzi, P., Mikado, S., Minotti, A., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Nakamura, M., Nakano, T., Nakatsuka, Y., Naumov, D., Niwa, K., Ogawa, S., Okateva, N., Olchevsky, A., Omura, T., Ozaki, K., Paoloni, A., Park, B. D., Park, I. G., Pastore, A., Patrizii, L., Pennacchio, E., Pessard, H., Pistillo, C., Podgrudkov, D., Polukhina, N., Pozzato, M., Pretzl, K., Pupilli, F., Rescigno, R., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Rostovtseva, I., Rubbia, A., Russo, A., Ryazhskaya, O., Sato, O., Sato, Y., Schchedrina, T., Schembri, A., Schmidt-Parzefall, W., Shakiryanova, I., Sheshukov, A., Shibuya, H., Shiraishi, T., Shoziyoev, G., Simone, S., Sioli, M., Sirignano, C., Sirri, G., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strauss, T., Strolin, P., Suzuki, K., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tolun, P., Tufanli, S., Vilain, P., Vladimirov, M., Votano, L., Vuilleumier, J. -L., Wilquet, G., Wonsak, B., Yoon, C. S., Yoshida, J., Zaitsev, Y., Zemskova, S., and Zghiche, A.

Subjects
High Energy Physics - Experiment
Abstract

A first result of the search for \numu $\rightarrow$ \nue oscillations in the OPERA experiment, located at the Gran Sasso Underground Laboratory, is presented. The experiment looked for the appearance of \nue in the CNGS neutrino beam using the data collected in 2008 and 2009. Data are compatible with the non-oscillation hypothesis in the three-flavour mixing model. A further analysis of the same data constrains the non-standard oscillation parameters $\theta_{new}$ and $\Delta m^2_{new}$ suggested by the LSND and MiniBooNE experiments. For large $\Delta m^{2}_{new}$ values ($>$0.1 eV$^{2}$), the OPERA 90% C.L. upper limit on sin$^{2}(2\theta_{new})$ based on a Bayesian statistical method reaches the value $7.2 \times 10^{-3}$.

Published
2013

30. A prospective evaluation of pegylated interferon alfa-2a therapy in patients with polycythemia vera and essential thrombocythemia with a prior splanchnic vein thrombosis

Author

Mascarenhas, J., Kosiorek, H., Prchal, J., Yacoub, A., Berenzon, D., Baer, M. R., Ritchie, E., Silver, R. T., Kessler, C., Winton, E., Finazzi, M. C., Rambaldi, A., Vannucchi, A. M., Leibowitz, D., Rondelli, D., Arcasoy, M. O., Catchatourian, R., Vadakara, J., Rosti, V., Hexner, E., Kremyanskaya, M., Sandy, L., Tripodi, J., Najfeld, V., Farnoud, N., Salama, M. E., Weinberg, R. S., Rampal, R., Goldberg, J. D., Mesa, R., Dueck, A. C., and Hoffman, R.

Published
2019
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31. Measurement of the neutrino velocity with the OPERA detector in the CNGS beam using the 2012 dedicated data

Author

The OPERA Collaboration, Adam, T., Agafonova, N., Aleksandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Autiero, D., Badertscher, A., Dhahbi, A. Ben, Beretta, M., Bertolin, A., Bozza, C., Brugière, T., Brugnera, R., Brunet, F., Brunetti, G., Buettner, B., Buontempo, S., Carlus, B., Cavanna, F., Cazes, A., Chaussard, L., Chernyavsky, M., Chiarella, V., Chukanov, A., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Esposito, L. S., Favier, J., Felici, G., Ferber, T., Fini, R. A., Fukuda, T., Garfagnini, A., Giacomelli, G., Girerd, C., Goellnitz, C., Goldberg, J., Golubkov, D., Gornushkin, Y., Grella, G., Grianti, F., Guerin, C., Guler, A. M., Gustavino, C., Hagner, C., Hamada, K., Hara, T., Hierholzer, M., Hollnagel, A., Ishida, H., Ishiguro, K., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kawada, J., Kim, J. H., Kim, S. H., Kimura, M., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Lauria, A., Lazzaro, C., Lenkeit, J., Ljubicic, A., Longhin, A., Mancini-Terracciano, C., Malgin, A., Mandrioli, G., Marteau, J., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Migliozzi, P., Mikado, S., Monacelli, P., Montesi, M. C., Morishima, K., Moser, U., Muciaccia, M. T., Nakamura, M., Nakano, T., Nakatsuka, Y., Naumov, D., Nikitina, V., Ogawa, S., Olchevsky, A., Ozaki, K., Palamara, O., Paoloni, A., Park, B. D., Park, I. G., Pastore, A., Patrizii, L., Pennacchio, E., Pessard, H., Pistillo, C., Podgrudkov, D., Polukhina, N., Pozzato, M., Pretzl, K., Pupilli, F., Rescigno, R., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Rostovtseva, I., Rubbia, A., Russo, A., Ryazhskaya, O., Sato, O., Sato, Y., Schembri, A., Schmidt-Parzefall, W., Schuler, J., Shakiryanova, I., Sheshukov, A., Shibuya, H., Shoziyoev, G., Simone, S., Sioli, M., Sirignano, C., Sirri, G., Song, J. S., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strauss, T., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tolun, P., Tufanli, S., Vilain, P., Vladimirov, M., Votano, L., Vuilleumier, J. L., Wilquet, G., Wonsak, B., Wurtz, J., Yoon, C. S., Yoshida, J., Zaitsev, Y., Zemskova, S., Zghiche, A., and Zimmermann, R.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

In spring 2012 CERN provided two weeks of a short bunch proton beam dedicated to the neutrino velocity measurement over a distance of 730 km. The OPERA neutrino experiment at the underground Gran Sasso Laboratory used an upgraded setup compared to the 2011 measurements, improving the measurement time accuracy. An independent timing system based on the Resistive Plate Chambers was exploited providing a time accuracy of $\sim$1 ns. Neutrino and anti-neutrino contributions were separated using the information provided by the OPERA magnetic spectrometers. The new analysis profited from the precision geodesy measurements of the neutrino baseline and of the CNGS/LNGS clock synchronization. The neutrino arrival time with respect to the one computed assuming the speed of light in vacuum is found to be $\delta t_\nu \equiv TOF_c - TOF_\nu= (0.6 \pm 0.4\ (stat.) \pm 3.0\ (syst.))$ ns and $\delta t_{\bar{\nu}} \equiv TOF_c - TOF_{\bar{\nu}} = (1.7 \pm 1.4\ (stat.) \pm 3.1\ (syst.))$ ns for $\nu_{\mu}$ and $\bar{\nu}_{\mu}$, respectively. This corresponds to a limit on the muon neutrino velocity with respect to the speed of light of $-1.8 \times 10^{-6} < (v_{\nu}-c)/c < 2.3 \times 10^{-6}$ at 90% C.L. This new measurement confirms with higher accuracy the revised OPERA result., Comment: 14 pages, 4 figures

Published
2012
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32. Measurement of the neutrino velocity with the OPERA detector in the CNGS beam

Author

The OPERA Collaboration, Adam, T., Agafonova, N., Aleksandrov, A., Altinok, O., Sanchez, P. Alvarez, Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Autiero, D., Badertscher, A., Dhahbi, A. Ben, Bertolin, A., Bozza, C., Brugiere, T., Brugnera, R., Brunet, F., Brunetti, G., Buontempo, S., Carlus, B., Cavanna, F., Cazes, A., Chaussard, L., Chernyavsky, M., Chiarella, V., Chukanov, A., Colosimo, G., Crespi, M., D'Ambrosio, N., De Lellis, G., De Serio, M., Declais, Y., Sanchez, P. del Amo, Di Capua, F., Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Efthymiopoulos, I., Egorov, O., Ereditato, A., Esposito, L. S., Favier, J., Ferber, T., Fini, R. A., Fukuda, T., Garfagnini, A., Giacomelli, G., Giorgini, M., Giovannozzi, M., Girerd, C., Goldberg, J., Gollnitz, C., Golubkov, D., Goncharova, L., Gornushkin, Y., Grella, G., Grianti, F., Gschwendtner, E., Guerin, C., Guler, A. M., Gustavino, C., Hagner, C., Hamada, K., Hara, T., Enikeev, R., Hierholzer, M., Hollnagel, A., Ieva, M., Ishida, H., Ishiguro, K., Jakovcic, K., Jollet, C., Jones, M., Juget, F., Kamiscioglu, M., Kawada, J., Kim, S. H., Kimura, M., Kiritsis, E., Kitagawa, N., Klicek, B., Knuesel, J., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Lazzaro, C., Lenkeit, J., Ljubicic, A., Longhin, A., Malgin, A., Mandrioli, G., Marteau, J., Matsuo, T., Matveev, V., Mauri, N., Mazzoni, A., Medinaceli, E., Meisel, F., Meregaglia, A., Migliozzi, P., Mikado, S., Missiaen, D., Monacelli, P., Morishima, K., Moser, U., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Nakatsuka, Y., Naumov, D., Nikitina, V., Nitti, F., Ogawa, S., Okateva, N., Olchevsky, A., Palamara, O., Paoloni, A., Park, B. D., Park, I. G., Pastore, A., Patrizii, L., Pennacchio, E., Pessard, H., Pistillo, C., Polukhina, N., Pozzato, M., Pretzl, K., Pupilli, F., Rescigno, R., Riguzzi, F., Roganova, T., Rokujo, H., Rosa, G., Rostovtseva, I., Rubbia, A., Russo, A., Ryasny, V., Ryazhskaya, O., Sato, O., Sato, Y., Sahnoun, Z., Schembri, A., Schuler, J., Lavina, L. Scotto, Serrano, J., Shakiryanova, I., Sheshukov, A., Shibuya, H., Shoziyoev, G., Simone, S., Sioli, M., Sirignano, C., Sirri, G., Song, J. S., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S., Stipcevic, M., Strauss, T., Takahashi, S., Tenti, M., Terranova, F., Tezuka, I., Tioukov, V., Tolun, P., Tran, N. T., Tufanli, S., Vilain, P., Vladimirov, M., Votano, L., Vuilleumier, J. -L., Wilquet, G., Wonsak, B., Wurtz, J., Yakushev, V., Yoon, C. S., Yoshida, J., Zaitsev, Y., Zemskova, S., and Zghiche, A.

Subjects
High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract

The OPERA neutrino experiment at the underground Gran Sasso Laboratory has measured the velocity of neutrinos from the CERN CNGS beam over a baseline of about 730 km. The measurement is based on data taken by OPERA in the years 2009, 2010 and 2011. Dedicated upgrades of the CNGS timing system and of the OPERA detector, as well as a high precision geodesy campaign for the measurement of the neutrino baseline, allowed reaching comparable systematic and statistical accuracies. An arrival time of CNGS muon neutrinos with respect to the one computed assuming the speed of light in vacuum of (6.5 +/- 7.4(stat.)((+8.3)(-8.0)sys.))ns was measured corresponding to a relative difference of the muon neutrino velocity with respect to the speed of light (v-c)/c =(2.7 +/-3.1(stat.)((+3.4)(-3.3)(sys.))x10^(-6). The above result, obtained by comparing the time distributions of neutrino interactions and of protons hitting the CNGS target in 10.5 microseconds long extractions, was confirmed by a test performed at the end of 2011 using a short bunch beam allowing to measure the neutrino time of flight at the single interaction level., Comment: 34 pages, 22 figures This version replaces all previous ones

Published
2011
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33. Measurement of charm production in neutrino charged-current interactions

Author

Kayis-Topaksu, A., Önengüt, G., van Dantzig, R., de Jong, M., Oldeman, R. G. C., Güler, M., Köse, U., Tolun, P., Catanesi, M. G., Muciaccia, M. T., Winter, K., Van de Vyver, B., Vilain, P., Wilquet, G., Saitta, B., Di Capua, E., Ogawa, S., Shibuya, H., Hristova, I. R., Kawamura, T., Kolev, D., Meinhard, H., Panman, J., Rozanov, A., Tsenov, R., Uiterwijk, J. W. E., Zucchelli, P., Goldberg, J., Chikawa, M., Song, J. S., Yoon, C. S., Kodama, K., Ushida, N., Aoki, S., Hara, T., Delbar, T., Favart, D., Grégoire, G., Kalinin, S., Makhlioueva, I., Artamonov, A., Gorbunov, P., Khovansky, V., Shamanov, V., Tsukerman, I., Bruski, N., Frekers, D., Hoshino, K., Kawada, J., Komatsu, M., Miyanishi, M., Nakamura, M., Nakano, T., Narita, K., Niu, K., Niwa, K., Nonaka, N., Sato, O., Toshito, T., Buontempo, S., Cocco, A. G., D'Ambrosio, N., De Lellis, G., De Rosa, G., Di Capua, F., Fiorillo, G., Marotta, A., Messina, M., Migliozzi, P., Lavina, L. Scotto, Strolin, P., Tioukov, V., Okusawa, T., Dore, U., Loverre, P. F., Ludovici, L., Rosa, G., Santacesaria, R., Satta, A., Spada, F. R., Barbuto, E., Bozza, C., Grella, G., Romano, G., Sirignano, C., Sorrentino, S., Sato, Y., and Tezuka, I.

Subjects
High Energy Physics - Experiment
Abstract

The nuclear emulsion target of the CHORUS detector was exposed to the wide-band neutrino beam of the CERN SPS of 27 GeV average neutrino energy from 1994 to 1997. In total about 100000 charged-current neutrino interactions with at least one identified muon were located in the emulsion target and fully reconstructed, using newly developed automated scanning systems. Charmed particles were searched for by a program recognizing particle decays. The observation of the decay in nuclear emulsion makes it possible to select a sample with very low background and minimal kinematical bias. 2013 charged-current interactions with a charmed hadron candidate in the final state were selected and confirmed through visual inspection. The charm production rate induced by neutrinos relative to the charged-current cross-section is measured to be sigma(nu_mu N -> mu- C X)/sigma(CC) = (5.75 +-0.32 stat +-0.30 syst)%. The charm production cross-section as a function of the neutrino energy is also obtained. The results are in good agreement with previous measurements. The charm-quark hadronization produces the following charmed hadrons with relative fractions (in %): f_Dzero = 43.7+-4.5, f_Lambda_c^plus = 19.2+-4.2, f_Dplus = 25.3+-4.2, and f_D_splus = 11.8+-4.7., Comment: 16 pages, 5 figures

Published
2011
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34. Measurement of the atmospheric muon charge ratio with the OPERA detector

Author

OPERA Collaboration, Agafonova, N., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Autiero, D., Badertscher, A., Bagulya, A., Bertolin, A., Besnier, M., Bick, D., Boyarkin, V., Bozza, C., Brugière, T., Brugnera, R., Brunetti, G., Buontempo, S., Cazes, A., Chaussard, L., Chernyavsky, M., Chiarella, V., Chon-Sen, N., Chukanov, A., Cozzi, M., D'Amato, G., Corso, F. Dal, D'Ambrosio, N., De Lellis, G., D'eclais, Y., De Serio, M., Di Capua, F., Di Ferdinando, D., Di Giovanni, A., Di Marco, N., Dmitrievski, S., Dracos, M., Duchesneau, D., Dusini, S., Ebert, J., Egorov, O., Enikeev, R., Ereditato, A., Esposito, L. S., Favier, J., Felici, G., Ferber, T., Fini, R., Frekers, D., Fukuda, T., Fukushima, C., Galkin, V. I., Garfagnini, A., Giacomelli, G., Giorgini, M., Goellnitz, C., Goldberg, J., Golubkov, D., Goncharova, L., Gornushkin, Y., Grella, G., Grianti, F., Guler, M., Gustavino, C., Hagner, C., Hamada, K., Hara, T., Hierholzer, M., Hoshino, K., Ieva, M., Jakovcic, K., Jollet, C., Juget, F., Kazuyama, M., Kim, S. H., Kimura, M., Klicek, B., Knuesel, J., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Kubota, H., Lazzaro, C., Lenkeit, J., Ljubicic, A., Longhin, A., Lutter, G., Malgin, A., Mandrioli, G., Marotta, A., Marteau, J., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meisel, F., Meregaglia, A., Migliozzi, P., Mikado, S., Miyamoto, S., Monacelli, P., Morishima, K., Moser, U., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Naumov, D., Nikitina, V., Niwa, K., Nonoyama, Y., Ogawa, S., Olchevski, A., Oldorf, C., Orlova, G., Osedlo, V., Paniccia, M., Paoloni, A., Park, B. D., Park, I. G., Pastore, A., Patrizii, L., Pennacchio, E., Pessard, H., Pilipenko, V., Pistillo, C., Policastro, G., Polukhina, N., Pozzato, M., Pretzl, K., Publichenko, P., Pupilli, F., Rescigno, R., Roganova, T., Rokujo, H., Romano, G., Rosa, G., Rostovtseva, I., Rubbia, A., Russo, A., Ryasny, V., Ryazhskaya, O., Sato, O., Sato, Y., Schembri, A., Parzefall, W. Schmidt, Schroeder, H., Lavina, L. Scotto, Sheshukov, A., Shibuya, H., Simone, S., Sioli, M., Sirignano, C., Sirri, G., Song, J. S., Spinetti, M., Stanco, L., Starkov, N., Stipcevic, M., Strauss, T., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tezuka, I., Tioukov, V., Tolun, P., Tran, T., Tufanli, S., Vilain, P., Vladimirov, M., Votano, L., Vuilleumier, J. L., Wilquet, G., Wonsak, B., Yakushev, V., Yoon, C. S., Yoshioka, T., Yoshida, J., Zaitsev, Y., Zemskova, S., Zghiche, A., and Zimmermann, R.

Subjects
High Energy Physics - Experiment
Abstract

The OPERA detector at the Gran Sasso underground laboratory (LNGS) was used to measure the atmospheric muon charge ratio in the TeV energy region. We analyzed 403069 atmospheric muons corresponding to 113.4 days of livetime during the 2008 CNGS run. We computed separately the muon charge ratio for single and for multiple muon events in order to select different energy regions of the primary cosmic ray spectrum and to test the charge ratio dependence on the primary composition. The measured charge ratio values were corrected taking into account the charge-misidentification errors. Data have also been grouped in five bins of the "vertical surface energy". A fit to a simplified model of muon production in the atmosphere allowed the determination of the pion and kaon charge ratios weighted by the cosmic ray energy spectrum., Comment: 14 pages, 10 figures

Published
2010

35. Father absence at delivery at Pelonomi Tertiary Hospital in Bloemfontein: Reasons and associated demographic characteristics.

Author

van Rooyen, J. J., de Jager, L., du Plessis, S., Goldberg, J., Salvage, J., Sipika, S., and Joubert, G.

Subjects
DEMOGRAPHIC characteristics, BIRTHFATHERS, FATHERS, DELIVERY (Obstetrics), MOTHERS
Abstract

Background. The presence of fathers during the birth of their babies has been recognised as beneficial for both the mother and the baby. Objective. To investigate the reasons and demographic factors associated with father absence at delivery. Methods. We conducted a quantitative, cross-sectional study. Anonymous questionnaires were completed by mothers admitted to the postnatal ward at Pelonomi Tertiary Hospital in Bloemfontein, South Africa, after a live birth. Mothers answered questions regarding mother and father characteristics (age, employment, residence), whether the father was present or absent at delivery and the reasons for his absence. Results. The highest percentage (30.7%) of the 137 participating mothers was in the age range 20 - 25 years. More than half (56.2%) resided in Bloemfontein/Mangaung, and 70.6% were unemployed. Most mothers (68.4%) were multiparous. In total, 81.0% of fathers were absent at delivery, although 50.0% had planned to be at the delivery. The main reason for their absence was employment (52.7%), which can be substantiated by the fact that most fathers (80.3%) were employed. For more than half (58.1%) of the deliveries, neither the father nor any other person (family member or friend) was present at the delivery. There was no association between maternal or paternal demographics and father absence at delivery. Conclusion. Father absence was common. Community-based programmes must encourage father involvement in all spheres of their children's lives and create awareness of the impact that their presence during birth can have. [ABSTRACT FROM AUTHOR]

Published
2024
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39. Characterization of Objective Skin Color Changes during and after Breast and Chest Wall Radiotherapy and Correlation with Radiation-Induced Skin Toxicity in Breast Cancer Patients, Including Patients with Skin of Color

Author

Purswani, J., primary, Xiao, J., additional, Maisonet, O.G., additional, Cahlon, O., additional, Perez, C.A., additional, Tattersall, I., additional, Adotama, P., additional, Gutierrez, D., additional, Sulman, E.P., additional, Goldberg, J., additional, and Gerber, N.K., additional

Published
2023
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45. First observation of a tau neutrino charged current interaction with charm production in the OPERA experiment: OPERA Collaboration

Author

Agafonova, N., Aleksandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bertolin, A., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Chernyavskiy, M., Chukanov, A., Consiglio, L., D’Ambrosio, N., De Lellis, G., De Serio, M., del Amo Sanchez, P., Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievski, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Fini, R. A., Fornari, F., Fukuda, T., Galati, G., Garfagnini, A., Gentile, V., Goldberg, J., Gorbunov, S., Gornushkin, Y., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, T., Hollnagel, A., Ishiguro, K., Iuliano, A., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, S. H., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Laudisio, F., Lauria, A., Longhin, A., Loverre, P., Malgin, A., Malenica, M., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Miyanishi, M., Mizutani, F., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Niwa, K., Okateva, N., Ogawa, S., Ozaki, K., Paoloni, A., Paparella, L., Park, B. D., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sato, O., Schembri, A., Shakirianova, I., Shchedrina, T., Shibuya, H., Shibayama, E., Shiraishi, T., Simone, S., Sirignano, C., Sirri, G., Sotnikov, A., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Vasina, S., Vilain, P., Voevodina, E., Votano, L., Vuilleumier, J. L., Wilquet, G., and Yoon, C. S.

Published
2020
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47. Canonical General Relativity on a Null Surface with Coordinate and Gauge Fixing

Author

Goldberg, J. N. and Soteriou, C.

Subjects
General Relativity and Quantum Cosmology
Abstract

We use the canonical formalism developed together with David Robinson to st= udy the Einstein equations on a null surface. Coordinate and gauge conditions = are introduced to fix the triad and the coordinates on the null surface. Toget= her with the previously found constraints, these form a sufficient number of second class constraints so that the phase space is reduced to one pair of canonically conjugate variables: $\Ac_2\and\Sc^2$. The formalism is related to both the Bondi-Sachs and the Newman-Penrose methods of studying the gravitational field at null infinity. Asymptotic solutions in the vicinity of null infinity which exclude logarithmic behavior require the connection to fall off like $1/r^3$ after the Minkowski limit. This, of course, gives the previous results of Bondi-Sachs and Newman-Penrose. Introducing terms which fall off more slowly leads to logarithmic behavior which leaves null infinity intact, allows for meaningful gravitational radiation, but the peeling theorem does not extend to $\Psi_1$ in the terminology of Newman-Penrose. The conclusions are in agreement with those of Chrusciel, MacCallum, and Singleton. This work was begun as a preliminary study of a reduced phase space for quantization of general relativity., Comment: magnification set; pagination improved; 20 pages, plain tex

Published
1995
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48. Linearized Constraints in the Connection Representation: Hamilton-Jacobi Solution

Author

Goldberg, J. N. and Robinson, D. C.

Subjects
General Relativity and Quantum Cosmology
Abstract

Newman and Rovelli have used singular Hamilton-Jacobi transformations to reduce the phase space of general relativity in terms of the Ashtekar variables. Their solution of the gauge constraint cannot be inverted and indeed has no Minkowski space limit. Nonetheless, we exhibit an explicit Hamilton-Jacobi solution of all the linearized constraints. The result does not encourage an iterative solution, but it does indicate the origin of the singularity of the Newman-Rovelli result., Comment: 16 pages Plain Tex

Published
1994
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50. P32 MAJESTEC-1: CORRELATIVE ANALYSES OF TECLISTAMAB, A B-CELL MATURATION ANTIGEN (BCMA) X CD3 BISPECIFIC ANTIBODY, IN PATIENTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA (RRMM)

Author

van de Donk, N., primary, Cortes-Selva, D., additional, Casneuf, T., additional, Vishwamitra, D., additional, Stein, S., additional, Perova, T., additional, Ramos, E., additional, Van Steenbergen, L., additional, Boominathan, R., additional, Lau, O., additional, Davis, C., additional, Banerjee, A., additional, Stephenson, T., additional, Uhlar, C., additional, Kobos, R., additional, Goldberg, J., additional, Pei, L., additional, Trancucci, D., additional, Girgis, S., additional, Lin, S.X.W., additional, Wu, L.S., additional, Moreau, P., additional, Usmani, S., additional, Bahlis, N.J., additional, and Verona, R., additional

Published
2023
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