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13 results on '"González Campo, Cecilia"'

6. Model-based whole-brain perturbational landscape of neurodegenerative diseases

Author

Perl, Yonatan Sanz, primary, Fittipaldi, Sol, additional, González Campo, Cecilia, additional, Moguilner, Sebastián, additional, Cruzat, Josephine, additional, Herzog, Rubén, additional, Kringelbach, Morten, additional, Deco, Gustavo, additional, Prado, Pavel, additional, Ibañez, Agustín, additional, and Tagliazucchi, Enzo, additional

Published
2022
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7. Multidimensional inhibitory signatures of sentential negation in behavioral variant frontotemporal dementia

Author

Díaz-Rivera, Mariano N, primary, Birba, Agustina, additional, Fittipaldi, Sol, additional, Mola, Débora, additional, Morera, Yurena, additional, de Vega, Manuel, additional, Moguilner, Sebastian, additional, Lillo, Patricia, additional, Slachevsky, Andrea, additional, González Campo, Cecilia, additional, Ibáñez, Agustín, additional, and García, Adolfo M, additional

Published
2022
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9. Social concepts and the cerebellum: behavioural and functional connectivity signatures in cerebellar ataxic patients.

Author

Lopes da Cunha, Pamela, Fittipaldi, Sol, González Campo, Cecilia, Kauffman, Marcelo, Rodríguez-Quiroga, Sergio, Yacovino, Darío Andrés, Ibáñez, Agustín, Birba, Agustina, and García, Adolfo M.

Subjects
CEREBELLAR cortex, FUNCTIONAL connectivity, FUNCTIONAL magnetic resonance imaging, CEREBELLUM, CEREBELLAR ataxia, SOCIAL interaction
Abstract

Neurocognitive research on social concepts underscores their reliance on fronto-temporo-limbic regions mediating broad socio-cognitive skills. Yet, the field has neglected another structure increasingly implicated in social cognition: the cerebellum. The present exploratory study examines this link combining a novel naturalistic text paradigm, a relevant atrophy model and functional magnetic resonance imaging. Fifteen cerebellar ataxia (CA) patients with focal cerebellar atrophy and 29 matched controls listened to a social text (highlighting interpersonal events) as well as a non-social text (focused on a single person's actions), and answered comprehension questionnaires. We compared behavioural outcomes between groups and examined their association with cerebellar connectivity. CA patients showed deficits in social text comprehension and normal scores in the non-social text. Also, social text outcomes in controls selectively correlated with connectivity between the cerebellum and key regions subserving multi-modal semantics and social cognition, including the superior and medial temporal gyri, the temporal pole and the insula. Conversely, brain-behaviour associations involving the cerebellum were abolished in the patients. Thus, cerebellar structures and connections seem involved in processing social concepts evoked by naturalistic discourse. Such findings invite new theoretical and translational developments integrating social neuroscience with embodied semantics. This article is part of the theme issue 'Concepts in interaction: social engagement and inner experiences'. [ABSTRACT FROM AUTHOR]

Published
2023
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10. Multimodal mechanisms of human socially reinforced learning across neurodegenerative diseases

Author

Legaz, Agustina, primary, Abrevaya, Sofía, additional, Dottori, Martín, additional, González Campo, Cecilia, additional, Birba, Agustina, additional, Martorell Caro, Miguel, additional, Aguirre, Julieta, additional, Slachevsky, Andrea, additional, Aranguiz, Rafael, additional, Serrano, Cecilia, additional, Gillan, Claire M, additional, Leroi, Iracema, additional, García, Adolfo M, additional, Fittipaldi, Sol, additional, and Ibañez, Agustín, additional

Published
2021
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11. Multimodal mechanisms of human socially reinforced learning across neurodegenerative diseases.

Author

Legaz, Agustina, Abrevaya, Sofía, Dottori, Martín, Campo, Cecilia González, Birba, Agustina, Caro, Miguel Martorell, Aguirre, Julieta, Slachevsky, Andrea, Aranguiz, Rafael, Serrano, Cecilia, Gillan, Claire M, Leroi, Iracema, García, Adolfo M, Fittipaldi, Sol, Ibañez, Agustín, González Campo, Cecilia, and Martorell Caro, Miguel

Abstract

Social feedback can selectively enhance learning in diverse domains. Relevant neurocognitive mechanisms have been studied mainly in healthy persons, yielding correlational findings. Neurodegenerative lesion models, coupled with multimodal brain measures, can complement standard approaches by revealing direct multidimensional correlates of the phenomenon. To this end, we assessed socially reinforced and non-socially reinforced learning in 40 healthy participants as well as persons with behavioural variant frontotemporal dementia (n = 21), Parkinson's disease (n = 31) and Alzheimer's disease (n = 20). These conditions are typified by predominant deficits in social cognition, feedback-based learning and associative learning, respectively, although all three domains may be partly compromised in the other conditions. We combined a validated behavioural task with ongoing EEG signatures of implicit learning (medial frontal negativity) and offline MRI measures (voxel-based morphometry). In healthy participants, learning was facilitated by social feedback relative to non-social feedback. In comparison with controls, this effect was specifically impaired in behavioural variant frontotemporal dementia and Parkinson's disease, while unspecific learning deficits (across social and non-social conditions) were observed in Alzheimer's disease. EEG results showed increased medial frontal negativity in healthy controls during social feedback and learning. Such a modulation was selectively disrupted in behavioural variant frontotemporal dementia. Neuroanatomical results revealed extended temporo-parietal and fronto-limbic correlates of socially reinforced learning, with specific temporo-parietal associations in behavioural variant frontotemporal dementia and predominantly fronto-limbic regions in Alzheimer's disease. In contrast, non-socially reinforced learning was consistently linked to medial temporal/hippocampal regions. No associations with cortical volume were found in Parkinson's disease. Results are consistent with core social deficits in behavioural variant frontotemporal dementia, subtle disruptions in ongoing feedback-mechanisms and social processes in Parkinson's disease and generalized learning alterations in Alzheimer's disease. This multimodal approach highlights the impact of different neurodegenerative profiles on learning and social feedback. Our findings inform a promising theoretical and clinical agenda in the fields of social learning, socially reinforced learning and neurodegeneration. [ABSTRACT FROM AUTHOR]

Published
2022
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13. Dementia in Latin America : paving the way toward a regional action plan

Author

Pontificia Universidad Javeriana. Facultad de Medicina. Instituto de Envejecimiento, Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Psiquiatría y Salud Mental, Pontificia Universidad Javeriana. Facultad de Medicina. Hospital Universitario San Ignacio, Parra, Mario Alfredo, Báez, Sandra, Sedeño, Lucas, González Campo, Cecilia, Santamaría-García, Hernando, Aprahamian, Ivan, Bertolucci, Paulo HF, Bustin, Julián, Camargos Bicalho, Maria Aparecida, Cano Gutiérrez, Carlos Alberto, Caramelli, Paulo, Chaves, Marcia L. F., Cogram, Patricia, Costa Beber, Bárbara, Court, Felipe A., Cruz de Souza, Leonardo, Custodio, Nilton, Damian, Andres, de la Cruz, Myriam, Diehl Rodriguez, Roberta, Dozzi Brucki, Sonia María, Fajersztajn, Lais, Farías, Gonzalo A., De Felice, Fernanda G., Ferrari, Raffaele, Ferreira de Oliveira, Fabricio, Ferreira, Sergio T., Ferretti, Ceres, Figueredo Balthazar, Marcio Luiz, Ferreira Frota, Norberto Anizio, Fuentes, Patricio, García, Adolfo M., García, Patricia J., de Gobbi Porto, Fábio Henrique, Duque Peñailillo, Lissette, Willy Engler, Henry, Maier, Irene, Mata, Ignacio F., Gonzalez-Billault, Christian, López, Oscar L., Morelli, Laura, Nitrini, Ricardo, Quiroz, Yakeel T., Guerrero Barragan, Alejandra, Huepe, David, Joao Pio, Fabricio, Kimie Suemoto, Claudia, Kochhann, Renata, Kochen, Silvia, Kumfor, Fiona, Lanata, Serggio, Miller, Bruce, Lessa Mansur, Leticia, Lie Hosogi, Mirna, Lillo, Patricia, Llibre Guerra, Jorge, Lira, David, Lopera, Francisco, Comas, Adelina, Avila-Funes, José Alberto, Sosa, Ana Luisa, Ramos, Claudia, França Resende, Elisa de Paula, Snyder, Heather M., Tarnanas, Ioannis, Yokoyama, Jenifer, Llibre, Juan, Cardona, Juan Felipe, Possin, Kate, Kosik, Kenneth S., Montesinos, Rosa, Moguilner, Sebastian, Lourdes Solis, Patricia Cristina, Lucena Ferretti-Rebustini, Renata Eloah de, Martin Ramirez, Jeronimo, Matallana, Diana, Mbakile-Mahlanza, Lingani, Marques Ton, Alyne Mendonça, Melo Tavares, Ronnielly, Miotto, Eliane C., Muniz-Terrera, Graciela, Muñoz-Nevárez, Luis Arnoldo, Orozco, David, Okada de Oliveira, Maira, Piguet, Olivier, Pintado Caipa, Maritza, Piña Escudero, Stefanie Danielle, Porcello Schilling, Lucas, Rodrigues Palmeira, André Luiz, Sanches Yassuda, Mônica, Santacruz-Escudero, Jose Manuel, Bernardo Serafim, Rodrigo, Smid, Jerusa, Slachevsky, Andrea, Serrano, Cecilia, Soto-Añari, Marcio, Tadao Takada, Leonel, Tenenholz Grinberg, Lea, Lucio Teixeira, Antonio, Tonidandel Barbosa, Maira, Trépel, Dominic, Ibanez, Agustin, Pontificia Universidad Javeriana. Facultad de Medicina. Instituto de Envejecimiento, Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Psiquiatría y Salud Mental, Pontificia Universidad Javeriana. Facultad de Medicina. Hospital Universitario San Ignacio, Parra, Mario Alfredo, Báez, Sandra, Sedeño, Lucas, González Campo, Cecilia, Santamaría-García, Hernando, Aprahamian, Ivan, Bertolucci, Paulo HF, Bustin, Julián, Camargos Bicalho, Maria Aparecida, Cano Gutiérrez, Carlos Alberto, Caramelli, Paulo, Chaves, Marcia L. F., Cogram, Patricia, Costa Beber, Bárbara, Court, Felipe A., Cruz de Souza, Leonardo, Custodio, Nilton, Damian, Andres, de la Cruz, Myriam, Diehl Rodriguez, Roberta, Dozzi Brucki, Sonia María, Fajersztajn, Lais, Farías, Gonzalo A., De Felice, Fernanda G., Ferrari, Raffaele, Ferreira de Oliveira, Fabricio, Ferreira, Sergio T., Ferretti, Ceres, Figueredo Balthazar, Marcio Luiz, Ferreira Frota, Norberto Anizio, Fuentes, Patricio, García, Adolfo M., García, Patricia J., de Gobbi Porto, Fábio Henrique, Duque Peñailillo, Lissette, Willy Engler, Henry, Maier, Irene, Mata, Ignacio F., Gonzalez-Billault, Christian, López, Oscar L., Morelli, Laura, Nitrini, Ricardo, Quiroz, Yakeel T., Guerrero Barragan, Alejandra, Huepe, David, Joao Pio, Fabricio, Kimie Suemoto, Claudia, Kochhann, Renata, Kochen, Silvia, Kumfor, Fiona, Lanata, Serggio, Miller, Bruce, Lessa Mansur, Leticia, Lie Hosogi, Mirna, Lillo, Patricia, Llibre Guerra, Jorge, Lira, David, Lopera, Francisco, Comas, Adelina, Avila-Funes, José Alberto, Sosa, Ana Luisa, Ramos, Claudia, França Resende, Elisa de Paula, Snyder, Heather M., Tarnanas, Ioannis, Yokoyama, Jenifer, Llibre, Juan, Cardona, Juan Felipe, Possin, Kate, Kosik, Kenneth S., Montesinos, Rosa, Moguilner, Sebastian, Lourdes Solis, Patricia Cristina, Lucena Ferretti-Rebustini, Renata Eloah de, Martin Ramirez, Jeronimo, Matallana, Diana, Mbakile-Mahlanza, Lingani, Marques Ton, Alyne Mendonça, Melo Tavares, Ronnielly, Miotto, Eliane C., Muniz-Terrera, Graciela, Muñoz-Nevárez, Luis Arnoldo, Orozco, David, Okada de Oliveira, Maira, Piguet, Olivier, Pintado Caipa, Maritza, Piña Escudero, Stefanie Danielle, Porcello Schilling, Lucas, Rodrigues Palmeira, André Luiz, Sanches Yassuda, Mônica, Santacruz-Escudero, Jose Manuel, Bernardo Serafim, Rodrigo, Smid, Jerusa, Slachevsky, Andrea, Serrano, Cecilia, Soto-Añari, Marcio, Tadao Takada, Leonel, Tenenholz Grinberg, Lea, Lucio Teixeira, Antonio, Tonidandel Barbosa, Maira, Trépel, Dominic, and Ibanez, Agustin

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