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At present, coronavirus disease 2019 (COVID-19) is raging around the world. In Spain, the percentage of intensive care unit (ICU) patients is very high, as well as the mortality rate. This article discusses a 38-year-old woman admitted to the ICU for acute respiratory failure secondary to SARS-CoV-2 infection. Early physiotherapy improved lung secretion removal, respiratory mechanics outcomes, gas exchange, and muscle strength without adverse effects. Regarding the lack of information about physiotherapy effects in this context, these data are essential to demonstrate the feasibility of early physiotherapy in such patients who are young as well as older. Sin financiación 0.622 JCR (2020) Q4, 34/36 Gerontology 0.167 SJR (2020) Q4, 172/210 Physical Therapy, Sports Therapy and Rehabilitation No data IDR 2020 UEM

Two acute respiratory failure secondary to SARS-CoV-2 subjects were admitted to the Hospital Universitario Vall d´Hebron ICU and Hospital Universitario Nuestra Senora de Candelaria ICU. The ICU respiratory physiotherapy (RP) plays an essential role during all phases of ventilatory care. Still, regarding the lack of information about RP effects in this context, these data are crucial to demonstrate its feasibility to treat SARS-CoV-2 subjects in ARDS. First case: An asthmatic 38 yr woman, sedated and intubated. Second case: Woman, with cardiac arrest, 43 yr, septic shock, hypoxemic encephalopathy, and seizures tracheostomized after ten days in IMV, pleural effusion drained during IMV. Both subjects SARS-CoV-2 positive during Hospital admission. RP goals: to improve WOB, gas exchange, recruit collapsed area, remove lung secretions, IMV wean, muscle strength. Figure 2 shows the RP protocol. Closed system airway suctioning removed abundant semi-thick and yellowish secretion. Early mobilization to upper and lower limbs was performed. Before the successful weaning, the patient presented X-ray, IMV settings, gas exchange, and muscle strength improvements (fig 1).