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Your search keyword '"Graham, D.I."' showing total 167 results
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167 results on '"Graham, D.I."'

1. Association of APOE e4 and cerebrovascular pathology in traumatic brain injury

Author

Smith, C., Graham, D.I., Murray, L.S., Stewart, J., and Nicoll, J.A.R.

Subjects
Apolipoproteins -- Genetic aspects, Apolipoproteins -- Research, Stroke (Disease) -- Development and progression, Brain -- Injuries, Brain -- Development and progression, Brain -- Patient outcomes, Health, Psychology and mental health
Published
2006

2. Cerebral amyloid antiopathy in traumatic brain injury: assocation with apolipoprotien E genotype

Author

Leclerq, P.D., Murray, L.S., Smith, C., Graham, D.I., Nicoll, J.A.R., and Gentleman, S.M.

Subjects
Contusions -- Research, Apolipoproteins -- Research, Allelomorphism -- Research, Amyloidosis -- Research, Amyloidosis -- Diagnosis, Amyloidosis -- Risk factors, Brain -- Injuries, Brain -- Patient outcomes, Brain -- Research, Genotype, Health, Psychology and mental health
Published
2005

3. Sudden unexplained death in adults caused by intracranial pathology. (Original Article)

Author

Black, M. and Graham, D.I.

Subjects
Patient outcomes, Causes of, Mortality -- United Kingdom, Brain hemorrhage -- Patient outcomes, Sudden death -- Causes of -- Patient outcomes, Hemorrhage -- Patient outcomes, Brain -- Hemorrhage
Abstract

Sudden unexplained deaths as a result of intracranial lesions in adults are an important component of medicolegal practice and are best examined as a combined effort by a forensic pathologist, [...]

Published
2002

6. An improved eddy interaction model for numerical simulation of turbulent particle dispersion

Author

Graham, D.I.

Subjects
Turbulence -- Models, Lagrangian functions -- Models, Eddies -- Models, Engineering and manufacturing industries, Science and technology
Abstract

Three main effects have been observed in experimental investigations of the dispersion of low concentrations of solid particles in homogeneous turbulent flows, namely the crossing trajectories, inertia, and continuity effects. This paper discusses the development of a simple Lagrangian eddy interaction model to account for all three of these effects. By choosing the length, time, and velocity, scales in the model so as to be consistent with the corresponding scales in homogeneous, isotropic, and stationary turbulence, the proper limiting behavior is ensured both for fluid particles and for heavy solid particles. Because only one time step is required per eddy, the computational efficiency of the model is ensured.

Published
1996

7. Non-traumatic forensic neuropathology.

Author

Stewart, W., Black, M., Kalimo, H., and Graham, D.I.

Subjects
Dementia -- Research, Forensic pathology -- Research, Death -- Causes of -- Research
Abstract

Abstract The practicing Forensic Pathologist is likely to encounter case material in which either the cause of death or a major contribution to the cause of death is underlying damage [...]

Published
2004

8. Trials and tribulations of using (beta)-amyloid precursor protein immunohistochemistry to evaluate traumatic brain injury in adults.

Author

Graham, D.I., Smith, C., Reichard, R., Leclercq, P.D., and Gentleman, S.M.

Subjects
Immunohistochemistry -- Methods -- Analysis -- Research, Brain -- Injuries, Hypoglycemia -- Analysis -- Research, Carbon monoxide poisoning -- Analysis -- Research
Abstract

Abstract Axonal pathology is increasingly identified by β-amyloid precursor protein (βAPP) immunohistochemistry in the brains of patients who may or may not have a history of trauma. The presence of [...]

Published
2004

9. Long-term intracerebral inflammatory response after traumatic brain injury.

Author

Gentleman, S.M., Leclercq, P.D., Moyes, L., Graham, D.I., Griffin, W.S.T., Nicoll, J.A.R., and Smith, C.

Subjects
Cytokines -- Research -- Analysis, Inflammation -- Analysis -- Research, Brain -- Injuries, Nervous system -- Degeneration
Abstract

Abstract Epidemiological and pathological studies suggest that head injury is a significant risk factor for subsequent neurodegeneration and cognitive decline in later life. The precise mechanisms for the development of [...]

Published
2004

10. Measurement and prediction of surface shear stress in annular flume

Author

Graham, D.I., James, P.W., Jones, T.E.R., Davies, J.M., and Delo, E.A.

Subjects
Sedimentation and deposition -- Research, Shear flow -- Measurement, Flumes -- Usage, Engineering and manufacturing industries, Science and technology
Abstract

Cohesive sediment beds Occur in a variety of natural and man-made environments. A parameter that has a very significant influence on the sediment behavior is the critical shear stress. This is the shear stress at the sediment surface above which erosion will take place. The critical shear stress can be evaluated in the laboratory under conditions closely resembling those found in the field by use of an annular flume. The main purpose of the work described in this paper is to determine experimentally and numerically the velocity and surface shear stress fields generated by the flow of water in an annular flume. Very good agreement is found between measured circumferential velocity profiles, obtained by laser doppler anemometry, and profiles predicted by the computational fluid dynamics program HARWELL-FLOW3D. Measurements of the bed and wall shear stresses are made using hot-film probes and these also agree reasonably well with numerical predictions. Also of interest is the dependence of the sediment shear strength on sediment depth. By comparing measured eroded sediment contours with predicted shear stress profiles a simple method emerges for describing this dependence.

Published
1992

12. Turbulence modification in the limiting cases of heavy- and tracer-particles

Author

Graham, D.I.

Subjects
Turbulence -- Analysis, Particles -- Analysis, Fluid dynamics -- Analysis, Engineering and manufacturing industries, Science and technology
Abstract

Some numerical models for particle dispersion can lead to spurious nonzero turbulence kinetic energy sources for tracer-particles, while the source terms disappear in physical turbulence. This was gleaned from an analysis of source terms due to viscous drag on dispersed-phase particles in a simple turbulent flow. Negative contributions to the turbulence kinetic energy equations in kappa - epsilon solvers can also arise if the models are used for 'light' particles with low inertia.

Published
1997

13. Sequences specific for enterovirus detected in spinal cord from patients with motor neurone disease

Author

Woodall, C.J., Riding, M.H., Graham, D.I., and Clements, G.B.

Subjects
Health aspects, Causes of, Enteroviruses -- Health aspects, Amyotrophic lateral sclerosis -- Causes of -- Health aspects, Nervous system diseases -- Causes of -- Health aspects
Abstract

Objective--To investigate the association of enteroviruses with motor neurone disease, also known as amyotrophic lateral sclerosis. Design--Analysis by enterovirus polymerase chain reaction of wax embedded material from spinal cords taken [...]

Published
1994

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