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2. Impact of simplified HCV diagnostic strategies on the HCV epidemic among men who have sex with men in the era of HIV oral pre‐exposure prophylaxis in Taiwan: a modelling study

Author

Wu, Huei‐Jiuan, Shih, Sophy Tingfang, Applegate, Tanya L., Kwon, Jisoo A., Cunningham, Evan B., Grebely, Jason, and Gray, Richard T.

Subjects
HIV (Viruses) -- Drug therapy -- Diagnosis, Hepatitis C virus -- Health aspects -- Analysis -- Usage, RNA -- Health aspects -- Usage -- Analysis, Epidemiology -- Usage -- Analysis -- Health aspects, Health, World Health Organization
Abstract

: Introduction: Simplified hepatitis C virus (HCV) diagnostic strategies have the potential to improve HCV diagnoses and treatment. We aimed to investigate the impact of simplified HCV diagnostic strategies on HCV incidence and its effect on HCV diagnosis and treatment among men who have sex with men (MSM) regardless of HIV status and use of HIV pre‐exposure prophylaxis (PrEP) in Taiwan. Methods: A compartmental deterministic model was developed to describe the natural history of HCV disease progression, the HCV care cascade and the HIV status and PrEP using among MSM. The model was calibrated to available data for HCV and HIV epidemiology and population demographics in Taiwan. We simulated the epidemic from 2004 and projected the impact of simplified testing strategies on the HCV epidemic among MSM over 2022–2030. Results: Under the current testing approach in Taiwan, total HCV incidence would increase to 12.6 per 1000 person‐years among MSM by 2030. Single‐visit point‐of‐care RNA testing had the largest impact on reducing the number of new HCV infections over 2022–2030, with a 31.1% reduction (interquartile range: 24.9%−32.8%). By 2030, single‐visit point‐of‐care HCV testing improved HCV diagnosis to 90.9%, HCV treatment to 87.7% and HCV cure to 81.5% among MSM living with HCV. Compared to status quo, prioritized simplified HCV testing for PrEP users and MSM living with diagnosed HIV had considerable impact on the broader HCV epidemic among MSM. A sensitivity analysis suggests that reinfection risk would have a large impact on the effectiveness of each point‐of‐care testing scenario. Conclusions: Simplified HCV diagnostic strategies could control the ongoing HCV epidemic and improve HCV testing and treatment among Taiwanese MSM. Single‐visit point‐of‐care RNA testing would result in large reductions in HCV incidence and prevalence among MSM. Efficient risk‐reduction strategies will need to be implemented alongside point‐of‐care testing to achieve HCV elimination among MSM in Taiwan., INTRODUCTION Among men who have sex with men (MSM), hepatitis C virus (HCV) is transmitted via sexual contact and sharing of unsterile injecting equipment and disproportionately affects MSM living with [...]

Published
2024
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5. Sex and gender differences in hepatitis C virus risk, prevention, and cascade of care in people who inject drugs: systematic review and meta-analysis

Author

Levinsson, Anna, Zolopa, Camille, Vakili, Farzaneh, Udhesister, Sasha, Kronfli, Nadine, Maheu-Giroux, Mathieu, Bruneau, Julie, Valerio, Heather, Bajis, Sahar, Read, Phillip, Martró, Elisa, Boucher, Lisa, Morris, Leith, Grebely, Jason, Artenie, Adelina, Stone, Jack, Vickerman, Peter, and Larney, Sarah

Published
2024
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7. Factors associated with experiencing stigma, discrimination, and negative health care treatment among people who inject drugs

Author

Broady, Timothy R., Valerio, Heather, Alavi, Maryam, Wheeler, Alice, Silk, David, Martinello, Marianne, Conway, Anna, Milat, Andrew, Dunlop, Adrian, Murray, Carolyn, Henderson, Charles, Amin, Janaki, Read, Phillip, Marks, Philippa, Degenhardt, Louisa, Stevens, Annabelle, Prain, Bianca, Hayllar, Jeremy, Reid, David, Montebello, Mark, Wade, Alexandra, Christmass, Michael, Cock, Victoria, Dore, Gregory J., Treloar, Carla, and Grebely, Jason

Published
2024
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9. 96-week retention in treatment with extended-release subcutaneous buprenorphine depot injections among people with opioid dependence: Extended follow-up after a single-arm trial

Author

Farrell, Michael, Shahbazi, Jeyran, Chambers, Mark, Byrne, Marianne, Gholami, Jaleh, Zahra, Emma, Grebely, Jason, Lintzeris, Nicholas, Larance, Briony, Ali, Robert, Nielsen, Suzanne, Dunlop, Adrian, Dore, Gregory J., McDonough, Michael, Montebello, Mark, Weiss, Rob, Rodgers, Craig, Cook, Jon, and Degenhardt, Louisa

Published
2024
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12. Direct-acting antiviral therapies for hepatitis C infection: global registration, reimbursement, and restrictions

Author

Sargsyants, N., Suleymanova, L., Salkic, N., Simonova, M., Nemeth-Blazic, T., Mravcik, V., Kivimets, K., Salupere, R., Butsashvili, M., Soselia, G., Makara, M., Tolmane, I., Jancorienė, L., Stratulat, S., Flisiak, R., Gheorghe, L., Cernat, R., Lakhov, A., Stanevich, O., Jarcuska, P., Peck-Radosavljevic, M., Robaeys, G., Øvrehus, A., Foster, G., Sutinen, J., Farkkila, M., Rautiainen, H., Vuoti, S., Nikolova, D., Pawlotsky, J.M., Rockstroh, J., Sypsa, V., Papatheodoridis, G., Olafsson, S., Feeney, E., Teti, E., Seguin-Devaux, C., Pocock, J., Reiff, S., McDougall, N., Van der Valk, M., Dalgard, O., Tato Marinho, R., Dillon, J., Peters, E., Bojovic, K., Matičič, M., Kåberg, M., Bruggmann, P., Healy, B., Chong, V.H., Yi, S., Tucker, J., Pasaribu, L.R., Tanaka, J., Ashley, E.A., Abu Hassan, M.R., Mohammed, N.S., Chan, H.K., Gidaagaya, S., Kyi, K.P., Hyung Joon, K., Chin, B., Baladjay, P.C., Kao, J.H., Wansom, T., da Cruz, B., Flower, B., Ehsan, E., Al Mahtab, M., Khandu, L., Bhadoria, A.S., Alavi, M., KC, P., Hamid, S., Biryukov, S., Alymbaeva, D., Alaei, A., Bakieva, S., Flichman, D., Carmo, R.F., Valdez, E., Cortes, C.P., Contreras, F., Teran, E., Velez-Moller, P., Jagnarine, T., Mills, M., Goodman-Meza, D., Sánchez, J., Montenegro-Idrogo, J.J., Lugo Canales, A.M., Davy, J., Alexander, A., Gerona, S., Perazzo, R., Balak, D., Kelly-Hanku, A., Fineanganofo, A., Gane, E., Raymond, N., Debzi, N., Sridharan, K., Waked, I., Turner, D., Shibolet, O., Al Muzaini, A., El Nakib, M., Sheriff, D.S., Brahni, T., Essayagh, T., Essayagh, S., Hjaija, D., Al-Naamani, K., Sanai, F.M., Pasquale, H., Bedri, S., Chakroun, M., Ghrabi, A., Akarca, U.S., Falcao, V., Edmond Gbedo, S., Ouoba, S., Nyabenda, F., Rocher Mbella, M., Mahamat Moussa, A., Youssouf, T., Boniface, Y., Akilimali Shindano, T., Hamida, M.E., Mongo, A., Mapapa, C., Desalegn, H., Embinga, E.L.A., Ndow, G., Nartey, Y., Cisse, M., Djalo, M.A., Mugambi, M., Nyakowa, M., Jeuronlon, M.K., Ngoma, J., Manitrala Ramanampamonjy, R., Naik, K., Soyjaudah, M.D., Filipe, E., Nnakelu, E., Serumondo, J., Mbodj, M., Patino, M., Aalto, M.K., Waweru, P., Dagnra, A., Ocama, P., Maghimbi, A., Hamooya, B.M., Katsidzira, L., Rios, C., Thormann, M., Al Marzooqi, N., Al Rand, H.M., Francois, K., Hamoudi, W., Alkharty, M., Skripo, O., Uka, T., Marshall, Alison D, Willing, Alex R, Kairouz, Abe, Cunningham, Evan B, Wheeler, Alice, O’Brien, Nicholas, Perera, Vidura, Ward, John W, Hiebert, Lindsey, Degenhardt, Louisa, Hajarizadeh, Behzad, Colledge, Samantha, Hickman, Matthew, Jawad, Danielle, Lazarus, Jeffrey V, Matthews, Gail V, Scheibe, Andrew, Vickerman, Peter, Dore, Gregory J, and Grebely, Jason

Published
2024
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13. Progress towards elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission update

Author

Cooke, Graham S, Flower, Barnaby, Cunningham, Evan, Marshall, Alison D, Lazarus, Jeffrey V, Palayew, Adam, Jia, Jidong, Aggarwal, Rakesh, Al-Mahtab, Mamum, Tanaka, Yashuito, Jeong, Sook-Hyang, Poovorawan, Kittiyod, Waked, Imam, Hiebert, Lindsey, Khue, Pham M, Grebely, Jason, Alcantara-Payawal, Diana, Sanchez-Avila, Juan F, Mbendi, Charles, Muljono, David H, Lesi, Olufunmilayo, Desalegn, Hailemichael, Hamid, Saeed, de Araujo, Alexandre, Cheinquer, Hugo, Onyekwere, Charles A, Malyuta, Ruslan, Ivanchuk, Iryna, Thomas, David L, Pimenov, Nikolay, Chulanov, Vladimir, Dirac, Mae Ashworth, Han, Hannah, and Ward, John W

Published
2024
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14. Health-Related Quality of Life of People Who Inject Drugs: The Enhancing Treatment of Hepatitis C in Opioid Substitution Settings Engage Study

Author

Grebely, Jason, Dore, Gregory J., Silk, David, Bath, Nicky, Treloar, Carla, Milat, Andrew, Dunlop, Adrian, Amin, Janaki, Holden, Jo, Murray, Carolyn, Henderson, Charles, Leadbeatter, Kyle, Day, Emma, Habraken, Nikitah, Dawson, Olivia, Degenhardt, Louisa, Scott, Clarke, Read, Phillip, Valerio, Heather, Tillakeratne, Shane, Marks, Philippa, Jayasinghe, Indika, Martinez, Maria, Reid, Hannah, Gleeson, Valerie, Van Dyk, Jodi, Mercade, Gerard Estivill, Marshall, Alison D., Obeid, Stephanie, Wheeler, A., Hooshyar, Samira Hosseini, Catlett, Beth, Verich, Andrey, Conway, Anna, Erratt, Amanda, Wheeler, Alice, Ezard, Nadine, Reid, David, Gorton, Carla, Hayllar, Jeremy, Lam, Thao, Datta, Prasun, Wade, Alex, Spruce, Sally, Cock, Vicky, Cornwell, Mark, Zohrab, Krista, Christmass, Michael, Connelly, Craig, Cooper, Angela, Montebello, Mark, Cherry, Robert, Dyer, Julie, Arawal, Shikha, Press, Elke, Horasak, Nadine, Lewis, Rhondda, Carthew, Astrid, Morris, Daniel, Donohue, Kathy, Griffiths, Kathy, Lana, Jason Dalla, Shin, Sue, Graf, Connie, Hampson, Adele, Qian, Siyu, Brown, Danielle, Lautier, Amber, Curran, Cate, Burns, Carina, Raidu, Ravina, Stolzenhein, Kylie, Brabender, Wanda, Somes, Kelly, Abram, Nargis, Turne, Rick, Larter, Stuart, Goodberg, Fiona, Luksza, Jennifer, Hall, Michelle, Hazelwood, Susan, Ismay, Charlotte, McClurg, Belinda, Mincham, Cherie, Barlow, Kali, Hoskins, Anita, Salisbury, Kate, Markham, Julie, Talmet, Jacky, Dunn, Sandy, Mitchell, Amanda, McKinnon, Andrew, Smyth, Fionnualh, Snell, Lisa, Laing, Elizabeth, Clark, Martin, Dorigo, Justin, Carman, Louise, Fergusson, Brent, Puszka, Bonny, Duncan, Gai, Baker, Fiona, Walsh, Jayde, Walsh, Leeann, Adey, Sara, Hinton, Rodd, Joyce, Melanie, Woods, Cheryl, Jenart, Alain, Everingham, Hope, Jansen, Louisa, Pepolim, Lucy, Clark, Kathy, Murphy, Lyn, Iliffe, Joel, Cheng, Qinglu, Cunningham, Evan B., and Shih, Sophy T.F.

Published
2024
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15. Global, regional, and country-level coverage of testing and treatment for HIV and hepatitis C infection among people who inject drugs: a systematic review

Author

Hajarizadeh, Behzad, Kairouz, Abe, Ottaviano, Sophie, Ireland, Jeremy, Willing, Alex, Cunningham, Evan, Webb, Paige, Colledge-Frisby, Samantha, Wheeler, Alice, Leung, Janni, Tran, Lucy T, Price, Olivia, Vickerman, Peter, Farrell, Michael, Hickman, Matthew, Dore, Gregory J, Bergenström, Anne, Degenhardt, Louisa, and Grebely, Jason

Published
2023
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17. Testing, diagnosis, and treatment following the implementation of a program to provide dried blood spot testing for HIV and hepatitis C infections: the NSW DBS Pilot

Author

Carrington, Nigel, Conway, Anna, Grebely, Jason, Starr, Mitchell, Catlett, Beth, Stevens, Annabelle, Prain, Bianca, McGrath, Colette, Causer, Louise, Guy, Rebecca, Holden, Joanne, Keen, Phillip, Kingsland, Melanie, Lu, Heng, Power, Cherie, Read, Phillip, Murray, Carolyn, McNulty, Anna, and Cunningham, Philip

Published
2024
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19. Global prevalence, cascade of care, and prophylaxis coverage of hepatitis B in 2022: a modelling study

Author

Razavi-Shearer, Devin, Gamkrelidze, Ivane, Pan, Calvin, Jia, Jidong, Berg, Thomas, Gray, Richard, Lim, Young-Suk, Chen, Chien-Jen, Ocama, Ponsiano, Desalegn, Hailemichael, Abbas, Zaigham, Abdallah, Ayat, Aghemo, Alessio, Ahmadbekova, Sabohat, Ahn, Sang Hoon, Aho, Inka, Akarca, Ulus, Al Masri, Nasser, Alalwan, Abduljaleel, Alavian, Seyed, Al-Busafi, Said, Aleman, Soo, Alfaleh, Faleh, Alghamdi, Abdullah, Al-Hamoudi, Waleed, Aljumah, Abdulrahman, Al-Naamani, Khalid, Al-Rifai, Ahmad, Alserkal, Yousif, Altraif, Ibrahim, Amarsanaa, Jazag, Anderson, Motswedi, Andersson, Monique, Armstrong, Paige, Asselah, Tarik, Athanasakis, Kostas, Baatarkhuu, Oidov, Ben-Ari, Ziv, Bensalem, Aicha, Bessone, Fernando, Biondi, Mia, Bizri, Abdul Rahman, Blach, Sarah, Braga, Wornei, Brandão-Mello, Carlos, Brosgart, Carol, Brown, Kimberly, Brown, Jr, Robert, Bruggmann, Philip, Brunetto, Maurizia, Buti, Maria, Cabezas, Joaquin, Casanovas, Teresa, Chae, Chungman, Chan, Henry Lik Yuen, Cheinquer, Hugo, Chen, Pei-Jer, Cheng, Kent Jason, Cheon, Myeong-Eun, Chien, Cheng-Hung, Choudhuri, Gourdas, Christensen, Peer Brehm, Chuang, Wan-Long, Chulanov, Vladimir, Cisneros, Laura, Coffin, Carla, Contreras, Fernando, Coppola, Nicola, Cornberg, Markus, Cowie, Benjamin, Cramp, Matthew, Craxi, Antonio, Crespo, Javier, Cui, Fuqiang, Cunningham, Chris, Dalgard, Olav, De Knegt, Robert, De Ledinghen, Victor, Dore, Gregory, Drazilova, Sylvia, Duberg, Ann-Sofi, Egeonu, Steve, Elbadri, Mohammed, El-Kassas, Mohamed, El-Sayed, Manal, Estes, Chris, Etzion, Ohad, Farag, Elmobashar, Ferradini, Laurent, Ferreira, Paulo, Flisiak, Robert, Forns, Xavier, Frankova, Sona, Fung, James, Gane, Edward, Garcia, Virginia, García-Samaniego, Javier, Gemilyan, Manik, Genov, Jordan, Gheorghe, Liliana, Gholam, Pierre, Gish, Robert, Goleij, Pouya, Gottfredsson, Magnus, Grebely, Jason, Gschwantler, Michael, Guingane, Nanelin Alice, Hajarizadeh, Behzad, Hamid, Saeed, Hamoudi, Waseem, Harris, Aaron, Hasan, Irsan, Hatzakis, Angelos, Hellard, Margaret, Hercun, Julian, Hernandez, Javier, Hockicková, Ivana, Hsu, Yao-Chun, Hu, Ching-Chih, Husa, Petr, Janicko, Martin, Janjua, Naveed, Jarcuska, Peter, Jaroszewicz, Jerzy, Jelev, Deian, Jeruma, Agita, Johannessen, Asgeir, Kåberg, Martin, Kaita, Kelly, Kaliaskarova, Kulpash, Kao, Jia-Horng, Kelly-Hanku, Angela, Khamis, Faryal, Khan, Aamir, Kheir, Omer, Khoudri, Ibtissam, Kondili, Loreta, Konysbekova, Aliya, Kristian, Pavol, Kwon, Jisoo, Lagging, Martin, Laleman, Wim, Lampertico, Pietro, Lavanchy, Daniel, Lázaro, Pablo, Lazarus, Jeffrey V, Lee, Alice, Lee, Mei-Hsuan, Liakina, Valentina, Lukšić, Boris, Malekzadeh, Reza, Malu, Abraham, Marinho, Rui, Mendes-Correa, Maria Cássia, Merat, Shahin, Meshesha, Berhane Redae, Midgard, Håvard, Mohamed, Rosmawati, Mokhbat, Jacques, Mooneyhan, Ellen, Moreno, Christophe, Mortgat, Laure, Müllhaupt, Beat, Musabaev, Erkin, Muyldermans, Gaëtan, Naveira, Marcelo, Negro, Francesco, Nersesov, Alexander, Nguyen, Van Thi Thuy, Ning, Qing, Njouom, Richard, Ntagirabiri, Rénovat, Nurmatov, Zuridin, Oguche, Stephen, Omuemu, Casimir, Ong, Janus, Opare-Sem, Ohene, Örmeci, Necati, Orrego, Mauricio, Osiowy, Carla, Papatheodoridis, George, Peck-Radosavljevic, Markus, Pessoa, Mário, Pham, Trang, Phillips, Richard, Pimenov, Nikolay, Pincay-Rodríguez, Loreley, Plaseska-Karanfilska, Dijana, Pop, Cora, Poustchi, Hossein, Prabdial-Sing, Nishi, Qureshi, Huma, Ramji, Alnoor, Rautiainen, Henna, Razavi-Shearer, Kathryn, Remak, William, Ribeiro, Sofia, Ridruejo, Ezequiel, Ríos-Hincapié, Cielo, Robalino, Marcia, Roberts, Lewis, Roberts, Stuart, Rodríguez, Manuel, Roulot, Dominique, Rwegasha, John, Ryder, Stephen, Sadirova, Shakhlo, Saeed, Umar, Safadi, Rifaat, Sagalova, Olga, Said, Sanaa, Salupere, Riina, Sanai, Faisal, Sanchez-Avila, Juan F, Saraswat, Vivek, Sargsyants, Narina, Sarrazin, Christoph, Sarybayeva, Gulya, Schréter, Ivan, Seguin-Devaux, Carole, Seto, Wai-Kay, Shah, Samir, Sharara, Ala, Sheikh, Mahdi, Shouval, Daniel, Sievert, William, Simojoki, Kaarlo, Simonova, Marieta, Sinn, Dong Hyun, Sonderup, Mark, Sonneveld, Milan, Spearman, C Wendy, Sperl, Jan, Stauber, Rudolf, Stedman, Catherine, Sypsa, Vana, Tacke, Frank, Tan, Soek-Siam, Tanaka, Junko, Tergast, Tammo, Terrault, Norah, Thompson, Alexander, Thompson, Peyton, Tolmane, Ieva, Tomasiewicz, Krzysztof, Tsang, Tak-Yin, Uzochukwu, Benjamin, Van Welzen, Berend, Vanwolleghem, Thomas, Vince, Adriana, Voeller, Alexis, Waheed, Yasir, Waked, Imam, Wallace, Jack, Wang, Cong, Weis, Nina, Wong, Grace, Wong, Vincent, Wu, Jaw-Ching, Yaghi, Cesar, Yesmembetov, Kakharman, Yip, Terry, Yosry, Ayman, Yu, Ming-Lung, Yuen, Man-Fung, Yurdaydin, Cihan, Zeuzem, Stefan, Zuckerman, Eli, and Razavi, Homie

Published
2023
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22. Reinfection incidence and risk among people treated for recent hepatitis C virus infection

Author

Martinello, Marianne, Carson, Joanne M., Van Der Valk, Marc, Rockstroh, Jürgen K., Ingiliz, Patrick, Hellard, Margaret, Nelson, Mark, Lutz, Thomas, Bhagani, Sanjay, Kim, Arthur Y., Hull, Mark, Cordes, Christiane, Moon, Juhi, Feld, Jordan J., Gane, Ed, Rauch, Andri, Bruneau, Julie, Tu, Elise, Applegate, Tanya, Grebely, Jason, Dore, Gregory J., and Matthews, Gail V.

Published
2023
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24. Patient-Reported Outcomes During and After Hepatitis C Virus Direct-Acting Antiviral Treatment Among People Who Inject Drugs

Author

Grebely, Jason, Dore, Gregory, Marks, Philippa, Dalgard, Olav, Bruggmann, Philip, Stedman, Catherine, Lacombe, Karine, Powis, Jeff, Hellard, Margaret, Crawford, Sione, Swan, Tracy, Byrne, Jude, Coordinating Centre—Amanda Erratt, Melanie Lacalamita., Cunningham, Evan, Hajarizadeh, Behzad, Marks, Pip, Shaw, Ineke, Siriragavan, Sharmila, Amin, Janaki, Quiene, Sophie, Petoumenos, Kathy, Schmid, Patrick, Castro, Erika, Moriggia, Alberto, Daulouede, Jean-Pierre, Conway, Brian, Fraser, Christopher, Feld, Jordan, Bruneau, Julie, Cooper, Curtis, Gane, Ed, Matthews, Gail, Dunlop, Adrian, Kronborg, Ian, Shaw, David, Litwin, Alain, Norton, Brianna, Thurnheer, Maria Christine, Weltman, Martin, Read, Philip, Dillon, John, Kessler, Simone, Knapp, Cornelia, Oprandi, Lorenza, Messina, Paola, Pantic, Marzia, Le Cam, Manuela, Maitre, Cecilia, Andreassen, Jessica, Melkeraaen, Ingunn, Tollefsen, Merete Moen, Pagarigan, Hannah, Milne, Rozalyn, Mason, Kate, Kaznowski, Diana, Zou, Lily, Bouchard, Rachel, Kotsoros, Barbara, Muir, Miriam, Milloy, Jessica, Oliver, Victoria, Noonan, Tracy, Sevehon, Alison, Hazelwood, Susan, Hall, Michelle, Hagenauer, Michelle, Liddle, Rachel, Ferguson, Catherine, Agyemang, Linda, Patel, Hiral, Soloway, Irene, Cerocchi, Orlando, Lacalamita, Melanie, Fragomeli, Vincenzo, Gilliver, Rosie, Lothian, Rebecca, Cleary, Shirley, Johnston, Linda, Middleton, Sarah, D’Amico, Ronald, McGovern, Barbara, Anderson, Jonathan, Zhong, Ze, Keane, Fiona, Tatsch, Fernando, Brainard, Diana, McHutchison, John, Cheng, Qinglu, Cunningham, Evan B., Shih, Sophy, Artenie, Adelina A., Litwin, Alain H., Read, Phillip, Dunlop, Adrian J., Feld, Jordan J., and Dore, Gregory J.

Published
2023
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26. Epidemiology of injecting drug use, prevalence of injecting-related harm, and exposure to behavioural and environmental risks among people who inject drugs: a systematic review

Author

Degenhardt, Louisa, Webb, Paige, Colledge-Frisby, Samantha, Ireland, Jeremy, Wheeler, Alice, Ottaviano, Sophie, Willing, Alex, Kairouz, Abe, Cunningham, Evan B, Hajarizadeh, Behzad, Leung, Janni, Tran, Lucy T, Price, Olivia, Peacock, Amy, Vickerman, Peter, Farrell, Michael, Dore, Gregory J, Hickman, Matthew, and Grebely, Jason

Published
2023
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29. Single-visit hepatitis C point-of-care testing, linkage to nursing care, and peer-supported treatment among people with recent injecting drug use at a peer-led needle and syringe program: The TEMPO Pilot Study

Author

Grebely, Jason, Gilliver, Rosie, McNaughton, Tony, Conway, Anna, Cunningham, Evan, Henderson, Charles, Hadlow, Brett, Molloy, Katrina, Doab, Anna, Tillakeratne, Shane, Pepolim, Lucy, Harrod, Mary Ellen, Dore, Gregory J, and Read, Phillip

Published
2023
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30. Sex Discrepancies in the Protective Effect of Opioid Agonist Therapy on Incident Hepatitis C Infection

Author

Geddes, Louise, Iversen, Jenny, Wand, Handan, Esmaeili, Aryan, Tsui, Judith, Hellard, Margaret, Dore, Gregory, Grebely, Jason, Dietze, Paul, Bruneau, Julie, Prins, Maria, Morris, Megan D, Shoukry, Naglaa H, Lloyd, Andrew R, Kim, Arthur Y, Lauer, Georg, Cox, Andrea L, Page, Kimberly, and Maher, Lisa

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Hepatitis, HIV/AIDS, Infectious Diseases, Chronic Liver Disease and Cirrhosis, Prevention, Emerging Infectious Diseases, Liver Disease, Hepatitis - C, Digestive Diseases, Infection, Good Health and Well Being, Analgesics, Opioid, Female, Hepacivirus, Hepatitis C, Humans, Male, Prospective Studies, Substance Abuse, Intravenous, sex, hepatitis C virus, people who inject drugs, opioid agonist therapy, harm reduction, International Collaboration of Incident HIV and HCV in Injecting Cohorts (InC3) Collaborative, sex, hepatitis C virus, Biological Sciences, Medical and Health Sciences, Microbiology, Clinical sciences
Abstract

BackgroundWhile opioid agonist therapy (OAT) reduces the risk of hepatitis C virus (HCV) acquisition among people who inject drugs (PWID), protective effects may be attenuated in females. We used pooled data from an international collaboration of prospective cohorts to assess sex disparities in HCV incidence among PWID exposed to OAT.MethodsIndependent predictors of HCV infection were identified using Cox regression models with random effects after accounting for the clustering effect of study sites. Unadjusted and adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) are presented in sex-specific analyses.ResultsAmong 701 participants exposed to OAT, HCV incidence was 16.5/100 person-years of observation (PYO) (95% CI, 13.1-20.7) in females and 7.6/100 PYO (95% CI, 6.0-9.5) in males (female:male adjusted HR [aHR], 1.80 [95% CI, 1.37-2.22]; P < .001). Factors associated with HCV acquisition among females exposed to OAT included nonwhite race (aHR, 1.79 [95% CI, 1.25-2.56]; P = .001), unstable housing (aHR, 4.00 [95% CI, 3.62-4.41]; P < .001), daily or more frequent injection (aHR, 1.45 [95% CI, 1.01-2.08]; P = .042), and receptive syringe sharing (aHR, 1.43 [95% CI, 1.33-1.53]; P < .001).ConclusionsFemale PWID exposed to OAT are twice as likely as their male counterparts to acquire HCV. While there is a need for better understanding of sex differences in immune function and opioid pharmacokinetic and pharmacodynamic parameters, structural and behavioral interventions that target women are required to bolster the efficacy of OAT in preventing HCV transmission.

Published
2020

31. Empfehlungen zur Hepatitis Versorgung bei Drogenkonsumierenden

Author

Grebely, Jason, Robaeys, Geert, Bruggmann, Philip, Aghemo, Alessio, Backmund, Markus, Bruneau, Julie, Byrne, Jude, Dalgard, Olav, Feld, Jordan J., Hellard, Margaret, Hickman, Matthew, Kautz, Achim, Litwin, Alain, Lloyd, Andrew R., Mauss, Stefan, Prins, Maria, Swan, Tracy, Schaefer, Martin, Taylor, Lynn E., and Dore, Gregory J.

Published
2023
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32. Interventions to enhance testing and linkage to treatment for hepatitis C infection for people who inject drugs: A systematic review and meta-analysis

Author

Cunningham, Evan B., Wheeler, Alice, Hajarizadeh, Behzad, French, Clare E., Roche, Rachel, Marshall, Alison D., Fontaine, Guillaume, Conway, Anna, Bajis, Sahar, Valencia, Braulio M., Presseau, Justin, Ward, John W., Degenhardt, Louisa, Dore, Gregory J., Hickman, Matthew, Vickerman, Peter, and Grebely, Jason

Published
2023
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33. Recomendaciones para el manejo de la infección por el virus de la hepatitis C entre usuarios de drogas por vía parenteral

Author

Grebely, Jason, Robaeys, Geert, Bruggmann, Philip, Aghemo, Alessio, Backmund, Markus, Bruneau, Julie, Byrne, Jude, Dalgard, Olav, Feld, Jordan J., Hellard, Margaret, Hickman, Matthew, Kautz, Achim, Litwin, Alain, Lloyd, Andrew R., Mauss, Stefan, Prins, Maria, Swan, Tracy, Schaefer, Martin, Taylor, Lynn E., and Dore, Gregory J.

Published
2023
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34. Recommandations pour la prise en charge de l’infection par le virus de l’hépatite C chez les usagers de drogues par injection

Author

Grebely, Jason, Robaeys, Geert, Bruggmann, Philip, Aghemo, Alessio, Backmund, Markus, Bruneau, Julie, Byrne, Jude, Dalgard, Olav, Feld, Jordan J., Hellard, Margaret, Hickman, Matthew, Kautz, Achim, Litwin, Alain, Lloyd, Andrew R., Mauss, Stefan, Prins, Maria, Swan, Tracy, Schaefer, Martin, Taylor, Lynn E., and Dore, Gregory J.

Published
2023
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35. Hepatitis C virus transmission between eight high-income countries among men who have sex with men: a whole-genome analysis

Author

Adams, Tanya, Amjad, Sophia, Appelhans, Christina, Applegate, Tanya, Becker, Brigitta, Bhagani, Sanjay, Bouchard, Rachel, Braun, Dominique, Bruelisauer, Christine, Bruneau, Julie, Calcagnile, Selma, Carroll, Anne, Cerocchi, Orlando, Chronister, Karen, Cordes, Christiane, Dore, Greg, Evans, Fiona, Fedele, Serge, Feld, Jordan, Ferguson, Catherine, Fraser, Chris, Ganase, Bruce, Gane, Ed, George, Valerie, Gerlach, Christoph, Gilleece, Yvonne, Gilliver, Rosie, Grebely, Jason, Grube, Christina, Gustafson, Jenna, Haas, Annette, Hagenauer, Michelle, Harris, Marianne, Helder, Jeltje, Hellard, Margaret, Hirter, Daniela, Hull, Mark, Ingiliz, Patrick, Katz, Stephanie, Kim, Arthur, Kotsoros, Barbara, Lacalamita, Melanie, Lindergard, Gabriella, Lutz, Thomas, Macabodbod, Lester, Manz, Manuela, Marks, Pip, Martinello, Marianne, Matthews, Gail, Messina, Paola, Mohrmann, Karina, Monnich, Christine, Moon, Juhi, Moriggia, Alberto, Morris, Genevieve, Morrish, Thomas, Nelson, Mark, Oliver, Victoria, Patterson, Joanne, Peters, Martine, Petoumenos, Kathy, Porretta, Hadassa, Rauch, Andri, Raymode, Parizade, Read, Phillip, Reece, Stacey, Rockstroh, Jürgen, Saidi, Angelika, Sasadeusz, Joe, Scherler, Pia, Schröder, Reinhold, Selfridge, Marion, Sevehon, Alison, Shaw, David, Sulkowski, Mark, Tamaddoni, Mahshid, Thunder, Orla, Thurnheer, Maria Christine, Tu, Elise, Ustianowski, Andrew, van der Valk, Marc, Witele, Eric, Koopsen, Jelle, Rockstroh, Juergen, Applegate, Tanya L, Sacks-Davis, Rachel, Boesecke, Christoph, Rebers, Sjoerd, Dore, Gregory J, and Schinkel, Janke

Published
2023
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37. Direct-acting antiviral therapies for hepatitis C infection: global registration, reimbursement, and restrictions

Author

Marshall, Alison D, primary, Willing, Alex R, additional, Kairouz, Abe, additional, Cunningham, Evan B, additional, Wheeler, Alice, additional, O’Brien, Nicholas, additional, Perera, Vidura, additional, Ward, John W, additional, Hiebert, Lindsey, additional, Degenhardt, Louisa, additional, Hajarizadeh, Behzad, additional, Colledge, Samantha, additional, Hickman, Matthew, additional, Jawad, Danielle, additional, Lazarus, Jeffrey V, additional, Matthews, Gail V, additional, Scheibe, Andrew, additional, Vickerman, Peter, additional, Dore, Gregory J, additional, Grebely, Jason, additional, Sargsyants, N., additional, Suleymanova, L., additional, Salkic, N., additional, Simonova, M., additional, Nemeth-Blazic, T., additional, Mravcik, V., additional, Kivimets, K., additional, Salupere, R., additional, Butsashvili, M., additional, Soselia, G., additional, Makara, M., additional, Tolmane, I., additional, Jancorienė, L., additional, Stratulat, S., additional, Flisiak, R., additional, Gheorghe, L., additional, Cernat, R., additional, Lakhov, A., additional, Stanevich, O., additional, Jarcuska, P., additional, Peck-Radosavljevic, M., additional, Robaeys, G., additional, Øvrehus, A., additional, Foster, G., additional, Sutinen, J., additional, Farkkila, M., additional, Rautiainen, H., additional, Vuoti, S., additional, Nikolova, D., additional, Pawlotsky, J.M., additional, Rockstroh, J., additional, Sypsa, V., additional, Papatheodoridis, G., additional, Olafsson, S., additional, Feeney, E., additional, Teti, E., additional, Seguin-Devaux, C., additional, Pocock, J., additional, Reiff, S., additional, McDougall, N., additional, Van der Valk, M., additional, Dalgard, O., additional, Tato Marinho, R., additional, Dillon, J., additional, Peters, E., additional, Bojovic, K., additional, Matičič, M., additional, Kåberg, M., additional, Bruggmann, P., additional, Healy, B., additional, Chong, V.H., additional, Yi, S., additional, Tucker, J., additional, Pasaribu, L.R., additional, Tanaka, J., additional, Ashley, E.A., additional, Abu Hassan, M.R., additional, Mohammed, N.S., additional, Chan, H.K., additional, Gidaagaya, S., additional, Kyi, K.P., additional, Hyung Joon, K., additional, Chin, B., additional, Baladjay, P.C., additional, Kao, J.H., additional, Wansom, T., additional, da Cruz, B., additional, Flower, B., additional, Ehsan, E., additional, Al Mahtab, M., additional, Khandu, L., additional, Bhadoria, A.S., additional, Alavi, M., additional, KC, P., additional, Hamid, S., additional, Biryukov, S., additional, Alymbaeva, D., additional, Alaei, A., additional, Bakieva, S., additional, Flichman, D., additional, Carmo, R.F., additional, Valdez, E., additional, Cortes, C.P., additional, Contreras, F., additional, Teran, E., additional, Velez-Moller, P., additional, Jagnarine, T., additional, Mills, M., additional, Goodman-Meza, D., additional, Sánchez, J., additional, Montenegro-Idrogo, J.J., additional, Lugo Canales, A.M., additional, Davy, J., additional, Alexander, A., additional, Gerona, S., additional, Perazzo, R., additional, Balak, D., additional, Kelly-Hanku, A., additional, Fineanganofo, A., additional, Gane, E., additional, Raymond, N., additional, Debzi, N., additional, Sridharan, K., additional, Waked, I., additional, Turner, D., additional, Shibolet, O., additional, Al Muzaini, A., additional, El Nakib, M., additional, Sheriff, D.S., additional, Brahni, T., additional, Essayagh, T., additional, Essayagh, S., additional, Hjaija, D., additional, Al-Naamani, K., additional, Sanai, F.M., additional, Pasquale, H., additional, Bedri, S., additional, Chakroun, M., additional, Ghrabi, A., additional, Akarca, U.S., additional, Falcao, V., additional, Edmond Gbedo, S., additional, Ouoba, S., additional, Nyabenda, F., additional, Rocher Mbella, M., additional, Mahamat Moussa, A., additional, Youssouf, T., additional, Boniface, Y., additional, Akilimali Shindano, T., additional, Hamida, M.E., additional, Mongo, A., additional, Mapapa, C., additional, Desalegn, H., additional, Embinga, E.L.A., additional, Ndow, G., additional, Nartey, Y., additional, Cisse, M., additional, Djalo, M.A., additional, Mugambi, M., additional, Nyakowa, M., additional, Jeuronlon, M.K., additional, Ngoma, J., additional, Manitrala Ramanampamonjy, R., additional, Naik, K., additional, Soyjaudah, M.D., additional, Filipe, E., additional, Nnakelu, E., additional, Serumondo, J., additional, Mbodj, M., additional, Patino, M., additional, Aalto, M.K., additional, Waweru, P., additional, Dagnra, A., additional, Ocama, P., additional, Maghimbi, A., additional, Hamooya, B.M., additional, Katsidzira, L., additional, Rios, C., additional, Thormann, M., additional, Al Marzooqi, N., additional, Al Rand, H.M., additional, Francois, K., additional, Hamoudi, W., additional, Alkharty, M., additional, Skripo, O., additional, and Uka, T., additional

Published
2024
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38. Prevalence and factors associated with hospitalisation for bacterial skin infections among people who inject drugs: The ETHOS Engage Study

Author

Wheeler, Alice, Valerio, Heather, Cunningham, Evan B., Martinello, Marianne, Barocas, Joshua A., Colledge-Frisby, Samantha, Treloar, Carla, Amin, Janaki, Henderson, Charles, Read, Phillip, Matthews, Gail V., Dunlop, Adrian J., Gorton, Carla, Hayllar, Jeremy, Alavi, Maryam, Murray, Carolyn, Marks, Phillipa, Silk, David, Degenhardt, Louisa, Dore, Gregory J., and Grebely, Jason

Published
2022
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39. Declining prevalence of current HCV infection and increased treatment uptake among people who inject drugs: The ETHOS Engage study

Author

Valerio, Heather, Alavi, Maryam, Conway, Anna, Silk, David, Treloar, Carla, Martinello, Marianne, Milat, Andrew, Dunlop, Adrian, Murray, Carolyn, Henderson, Charles, Amin, Janaki, Read, Phillip, Marks, Philippa, Degenhardt, Louisa, Stevens, Annabelle, Prain, Bianca, Hayllar, Jeremy, Reid, David, Montebello, Mark, Wade, Alexandra, Christmass, Michael, Cock, Victoria, Dore, Gregory J, and Grebely, Jason

Published
2022
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40. Characteristics of hepatitis C virus resistance in an international cohort after a decade of direct-acting antivirals

Author

Martinello, Marianne, Matthews, Gail, Fernando, Fay Fabián, Esteban, Juan I., Müllhaupt, Beat, Wiesch, Julian Schulze zur, Buggisch, Peter, Neumann-Haefelin, Christoph, Berg, Thomas, Berg, Christoph P., Schattenberg, Jörn M., Moreno, Christophe, Stauber, Rudolf, Lloyd, Andrew, Dore, Gregory, Applegate, Tanya, Ignacio, Juan, Garcia-Cehic, Damir, Gregori, Josep, Rodriguez-Frias, Francisco, Rando, Ariadna, Gozlan, Yael, Angelico, Mario, Andreoni, Massimo, Babudieri, Sergio, Bertoli, Ada, Cento, Valeria, Coppola, Nicola, Craxì, Antonio, Paolucci, Stefania, Parruti, Giustino, Pasquazzi, Caterina, Perno, Carlo Federico, Teti, Elisabetta, Vironet, C., Lannergård, Anders, Duberg, Ann-Sofi, Aleman, Soo, Gutteberg, Tore, Soulier, Alexandre, Gourgeon, Aurélie, Chevaliez, Stephane, Pol, Stanislas, Carrat, Fabrice, Salmon, Dominique, Kaiser, Rolf, Knopes, Elena, Gomes, Perpetua, de Kneght, Rob, Rijnders, Bart, Poljak, Mario, Lunar, Maja, Usubillaga, Rafael, Seguin_Devaux, Carole, Tay, Enoch, Wilson, Caroline, Wang, Dao Sen, George, Jacob, Kok, Jen, Pérez, Ana Belén, Chueca, Natalia, García-Deltoro, Miguel, Martínez-Sapiña, Ana María, Lara-Pérez, María Magdalena, García-Bujalance, Silvia, Aldámiz-Echevarría, Teresa, Vera-Méndez, Francisco Jesús, Pineda, Juan Antonio, Casado, Marta, Pascasio, Juan Manuel, Salmerón, Javier, Alados-Arboledas, Juan Carlos, Poyato, Antonio, Téllez, Francisco, Rivero-Juárez, Antonio, Merino, Dolores, Vivancos-Gallego, María Jesús, Rosales-Zábal, José Miguel, Ocete, María Dolores, Simón, Miguel Ángel, Rincón, Pilar, Reus, Sergi, De la Iglesia, Alberto, García-Arata, Isabel, Jiménez, Miguel, Jiménez, Fernando, Hernández-Quero, José, Galera, Carlos, Balghata, Mohamed Omar, Primo, Joaquín, Masiá, Mar, Espinosa, Nuria, Delgado, Marcial, von-Wichmann, Miguel Ángel, Collado, Antonio, Santos, Jesús, Mínguez, Carlos, Díaz-Flores, Felícitas, Fernández, Elisa, Bernal, Enrique, De Juan, José, Antón, José Joaquín, Vélez, Mónica, Aguilera, Antonio, Navarro, Daniel, Arenas, Juan Ignacio, Fernández, Clotilde, Espinosa, María Dolores, Ríos, María José, Alonso, Roberto, Hidalgo, Carmen, Hernández, Rosario, Téllez, María Jesús, Rodríguez, Francisco Javier, Antequera, Pedro, Delgado, Cristina, Martín, Patricia, Crespo, Javier, Becerril, Berta, Pérez, Oscar, García-Herola, Antonio, Montero, José, Freyre, Carolina, Grau, Concepción, Cabezas, Joaquin, Jimenez, Miguel, Rodriguez, Manuel Alberto Macias, Quilez, Cristina, Pardo, Maria Rodriguez, Muñoz-Medina, Leopoldo, Figueruela, Blanca, Howe, Anita Y.M., Rodrigo, Chaturaka, Cunningham, Evan B., Douglas, Mark W., Dietz, Julia, Grebely, Jason, Popping, Stephanie, Sfalcin, Javier Alejandro, Parczewski, Milosz, Sarrazin, Christoph, de Salazar, Adolfo, Fuentes, Ana, Sayan, Murat, Quer, Josep, Kjellin, Midori, Kileng, Hege, Mor, Orna, Lennerstrand, Johan, Fourati, Slim, Di Maio, Velia Chiara, Chulanov, Vladimir, Pawlotsky, Jean-Michel, Harrigan, P. Richard, Ceccherini-Silberstein, Francesca, and Garcia, Federico

Published
2022
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41. Global change in hepatitis C virus prevalence and cascade of care between 2015 and 2020: a modelling study

Author

Blach, Sarah, Terrault, Norah A, Tacke, Frank, Gamkrelidze, Ivane, Craxi, Antonio, Tanaka, Junko, Waked, Imam, Dore, Gregory J, Abbas, Zaigham, Abdallah, Ayat R, Abdulla, Maheeba, Aghemo, Alessio, Aho, Inka, Akarca, Ulus S, Alalwan, Abduljaleel M, Alanko Blomé, Marianne, Al-Busafi, Said A, Aleman, Soo, Alghamdi, Abdullah S, Al-Hamoudi, Waleed K, Aljumah, Abdulrahman A, Al-Naamani, Khalid, Al Serkal, Yousif M, Altraif, Ibrahim H, Anand, Anil C, Anderson, Motswedi, Andersson, Monique I, Athanasakis, Kostas, Baatarkhuu, Oidov, Bakieva, Shokhista R, Ben-Ari, Ziv, Bessone, Fernando, Biondi, Mia J, Bizri, Abdul Rahman N, Brandão-Mello, Carlos E, Brigida, Krestina, Brown, Kimberly A, Brown, Jr, Robert S, Bruggmann, Philip, Brunetto, Maurizia R, Busschots, Dana, Buti, Maria, Butsashvili, Maia, Cabezas, Joaquin, Chae, Chungman, Chaloska Ivanova, Viktorija, Chan, Henry Lik Yuen, Cheinquer, Hugo, Cheng, Kent Jason, Cheon, Myeong-Eun, Chien, Cheng-Hung, Chien, Rong-Nan, Choudhuri, Gourdas, Christensen, Peer Brehm, Chuang, Wan-Long, Chulanov, Vladimir, Cisneros, Laura E, Coco, Barbara, Contreras, Fernando A, Cornberg, Markus, Cramp, Matthew E, Crespo, Javier, Cui, Fuqiang, Cunningham, Chris W, Dagher Abou, Lucy, Dalgard, Olav, Dao, Doan Y, De Ledinghen, Victor, Derbala, Moutaz F, Deuba, Keshab, Dhindsa, Karan, Djauzi, Samsuridjal, Drazilova, Sylvia, Duberg, Ann-Sofi, Elbadri, Mohammed, El-Sayed, Manal H, Esmat, Gamal, Estes, Chris, Ezzat, Sameera, Färkkilä, Martti A, Ferradini, Laurent, Ferraz, Maria Lucia G, Ferreira, Paulo R A, Filipec Kanizaj, Tajana, Flisiak, Robert, Frankova, Sona, Fung, James, Gamkrelidze, Amiran, Gane, Edward, Garcia, Virginia, García-Samaniego, Javier, Gemilyan, Manik, Genov, Jordan, Gheorghe, Liliana S, Gholam, Pierre M, Goldis, Adrian, Gottfredsson, Magnus, Gray, Richard T, Grebely, Jason, Gschwantler, Michael, Hajarizadeh, Behzad, Hamid, Saeed S, Hamoudi, Waseem, Hatzakis, Angelos, Hellard, Margaret E, Himatt, Sayed, Hofer, Harald, Hrstic, Irena, Hunyady, Bela, Husa, Petr, Husic-Selimovic, Azra, Jafri, Wasim S M, Janicko, Martin, Janjua, Naveed, Jarcuska, Peter, Jaroszewicz, Jerzy, Jerkeman, Anna, Jeruma, Agita, Jia, Jidong, Jonasson, Jon G, Kåberg, Martin, Kaita, Kelly D E, Kaliaskarova, Kulpash S, Kao, Jia-Horng, Kasymov, Omor T, Kelly-Hanku, Angela, Khamis, Faryal, Khamis, Jawad, Khan, Aamir G, Khandu, Lekey, Khoudri, Ibtissam, Kielland, Knut B, Kim, Do Young, Kodjoh, Nicolas, Kondili, Loreta A, Krajden, Mel, Krarup, Henrik Bygum, Kristian, Pavol, Kwon, Jisoo A, Lagging, Martin, Laleman, Wim, Lao, Wai Cheung, Lavanchy, Daniel, Lázaro, Pablo, Lazarus, Jeffrey V, Lee, Alice U, Lee, Mei-Hsuan, Li, Michael K K, Liakina, Valentina, Lim, Young-Suk, Löve, Arthur, Lukšić, Boris, Machekera, Shepherd Mufudzi, Malu, Abraham O, Marinho, Rui T, Maticic, Mojca, Mekonnen, Hailemichael D, Mendes-Correa, Maria Cássia, Mendez-Sanchez, Nahum, Merat, Shahin, Meshesha, Berhane Redae, Midgard, Håvard, Mills, Mike, Mohamed, Rosmawati, Mooneyhan, Ellen, Moreno, Christophe, Muljono, David H, Müllhaupt, Beat, Musabaev, Erkin, Muyldermans, Gaëtan, Nartey, Yvonne Ayerki, Naveira, Marcelo C M, Negro, Francesco, Nersesov, Alexander V, Njouom, Richard, Ntagirabiri, Rénovat, Nurmatov, Zuridin S, Obekpa, Solomon A, Oguche, Stephen, Olafsson, Sigurdur, Ong, Janus P, Opare-Sem, Ohene K, Orrego, Mauricio, Øvrehus, Anne L, Pan, Calvin Q, Papatheodoridis, George V, Peck-Radosavljevic, Markus, Pessoa, Mário G, Phillips, Richard O, Pimenov, Nikolay, Plaseska-Karanfilska, Dijana, Prabdial-Sing, Nishi N, Puri, Pankaj, Qureshi, Huma, Rahman, Aninda, Ramji, Alnoor, Razavi-Shearer, Devin M, Razavi-Shearer, Kathryn, Ridruejo, Ezequiel, Ríos-Hincapié, Cielo Y, Rizvi, S M Shahriar, Robaeys, Geert K M M, Roberts, Lewis R, Roberts, Stuart K, Ryder, Stephen D, Sadirova, Shakhlo, Saeed, Umar, Safadi, Rifaat, Sagalova, Olga, Said, Sanaa S, Salupere, Riina, Sanai, Faisal M, Sanchez-Avila, Juan F, Saraswat, Vivek A, Sarrazin, Christoph, Sarybayeva, Gulya, Seguin-Devaux, Carole, Sharara, Ala I, Sheikh, Mahdi, Shewaye, Abate B, Sievert, William, Simojoki, Kaarlo, Simonova, Marieta Y, Sonderup, Mark W, Spearman, C Wendy, Sperl, Jan, Stauber, Rudolf E, Stedman, Catherine A M, Su, Tung-Hung, Suleiman, Anita, Sypsa, Vana, Tamayo Antabak, Natalia, Tan, Soek-Siam, Tergast, Tammo L, Thurairajah, Prem H, Tolmane, Ieva, Tomasiewicz, Krzysztof, Tsereteli, Maia, Uzochukwu, Benjamin S C, Van De Vijver, David A M C, Van Santen, Daniela K, Van Vlierberghe, Hans, Van Welzen, Berend, Vanwolleghem, Thomas, Vélez-Möller, Patricia, Villamil, Federico, Vince, Adriana, Waheed, Yasir, Weis, Nina, Wong, Vincent W-S, Yaghi, Cesar G, Yesmembetov, Kakharman, Yosry, Ayman, Yuen, Man-Fung, Yunihastuti, Evy, Zeuzem, Stefan, Zuckerman, Eli, and Razavi, Homie A

Published
2022
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42. Interventions to enhance testing, linkage to care, and treatment initiation for hepatitis C virus infection: a systematic review and meta-analysis

Author

Cunningham, Evan B, Wheeler, Alice, Hajarizadeh, Behzad, French, Clare E, Roche, Rachel, Marshall, Alison D, Fontaine, Guillaume, Conway, Anna, Valencia, Braulio M, Bajis, Sahar, Presseau, Justin, Ward, John W, Degenhardt, Louisa, Dore, Gregory J, Hickman, Matthew, Vickerman, Peter, and Grebely, Jason

Published
2022
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43. Outcomes of a single-arm implementation trial of extended-release subcutaneous buprenorphine depot injections in people with opioid dependence

Author

Farrell, Michael, Shahbazi, Jeyran, Byrne, Marianne, Grebely, Jason, Lintzeris, Nicholas, Chambers, Mark, Larance, Briony, Ali, Robert, Nielsen, Suzanne, Dunlop, Adrian, Dore, Gregory J., McDonough, Michael, Montebello, Mark, Nicholas, Thomas, Weiss, Rob, Rodgers, Craig, Cook, Jon, and Degenhardt, Louisa

Published
2022
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45. Factors associated with hepatitis C treatment uptake among females of childbearing age in New South Wales, Australia: A population‐based study.

Author

Valerio, Heather, Alavi, Maryam, Marshall, Alison D., Hajarizadeh, Behzad, Amin, Janaki, Law, Matthew, Tillakeratne, Shane, George, Jacob, Degenhardt, Louisa, Grebely, Jason, Matthews, Gail V., and Dore, Gregory J.

Subjects
CHILDBEARING age, HEPATITIS C, INDIGENOUS Australians, DRUG addiction, HEPATITIS C virus
Abstract

Introduction: Females of childbearing age with hepatitis C virus (HCV) face increased marginalisation with intersecting, sex‐specific barriers to direct acting antiviral (DAA) therapy. We assessed the factors associated with uptake of DAA therapy among females of childbearing age, including those with evidence of recent drug dependence. Methods: HCV notifications in New South Wales, Australia (1995–2017) were linked to opioid agonist therapy (OAT), hospitalisations, incarcerations, perinatal, HIV notifications, deaths and prescription databases. Recent drug dependence was defined as hospitalisation due to injectable drugs or receipt of OAT occurring in the DAA era (2016–2018). Logistic regression was used to analyse factors associated with DAA uptake among females of childbearing age (18–44), including those with recent drug dependence. Results: Among 57,467 people with evidence of chronic HCV in the DAA era (2016–2018), 20,161 (35%) were female, including 33% (n = 6563/20,161) of childbearing age (18–44). Among all females of childbearing age (n = 6563) and those with evidence of recent drug dependence (n = 2278/6563, 35%), DAA uptake was lower among those who had given birth in the DAA era (vs. no birth record, all females of childbearing age; aOR: 0.74, 95% CI 0.61, 0.89; those with recent drug dependence; aOR 0.69, 95% CI 0.51, 0.93) and Aboriginal and Torres Strait Islander peoples (all females of childbearing age; aOR 0.81, 95% CI 0.71, 0.93; those with recent drug dependence aOR 0.75, 95% CI 0.62, 0.90). Conclusion: Females of childbearing age should be considered a key population for DAA therapy. Enhancing antenatal and postnatal HCV care may be critical in the pursuit towards elimination. [ABSTRACT FROM AUTHOR]

Published
2024
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46. Health utility among people who regularly use opioids in Australia.

Author

Tran, Anh Dam, Grebely, Jason, Chambers, Mark, Degenhardt, Louisa, Farrell, Michael, Bajis, Sahar, and Larance, Briony

Subjects
*OPIOIDS, *KRUSKAL-Wallis Test, *RESOURCE allocation, *QUALITY of life, *CONFIDENCE intervals
Abstract

Introduction: Studies of health utilities among people who use opioids have mostly been based on in‐treatment populations. We aim to report utility‐based quality of life by participants' socio‐demographic, drug and treatment characteristics, and to examine the determinants of health utility among people who use opioids regularly. Methods: Cross‐sectional study of participants who used opioids regularly, recruited across New South Wales, Victoria and Tasmania in 2018–2019. Differences in European Quality of Life (EQ‐5D‐5L) heath utility scores between socio‐demographic and clinical subgroups were assessed using non‐parametric Kruskal–Wallis test by rank. To address the unique distribution of EQ‐5D‐5L health utility scores in the current sample, a two‐part model was applied to assess factors associated with health utility. Results: Among 402 participants enrolled in the study, 385 (96%) completed the EQ‐5D‐5L questionnaire. The mean health utility of the total sample was 0.63 (SD 0.29). Participants who previously received opioid agonist treatment [OAT] (adj marginal effect (ME) −0.11; 95% confidence interval [CI] −0.20 to −0.02) and those currently in OAT (adj ME −0.13; 95% CI −0.22 to −0.06) reported lower health utility than those who had never received OAT. Participants who used both pharmaceutical opioids and benzodiazepines had lower health utility compared to no pharmaceutical opioids and no benzodiazepines use (adj ME −0.17; 95% CI −0.28 to −0.07). Discussion and Conclusions: Findings provide important health utility data for economic evaluations, useful for guiding allocation of resources for treatment strategies among people who use opioids. Lower health utilities among those using benzodiazepines and pharmaceutical opioids suggests interventions targeting these subgroups may be beneficial. [ABSTRACT FROM AUTHOR]

Published
2024
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47. Needle and syringe sharing among people who have recently injected drugs in Australia: The ETHOS Engage Study.

Author

Farooq, Abdullah, Valerio, Heather, Wheeler, Alice, Martinello, Marianne, Henderson, Charles, Silk, David, Degenhardt, Louisa, Read, Phillip, Dore, Gregory J., Grebely, Jason, Cunningham, Evan B., Bath, Nicky, Treloar, Carla, Milat, Andrew, Dunlop, Adrian, Amin, Janaki, Holden, Jo, Murray, Carolyn, Leadbeatter, Kyle, and Day, Emma

Subjects
NEEDLE sharing, HEPATITIS C virus, HARM reduction, DRUGS, ODDS ratio
Abstract

Introduction: Understanding needle/syringe sharing is crucial for reducing hepatitis C virus (HCV) infection and reinfection. This study aimed to assess the prevalence and factors associated with needle/syringe sharing among people who inject drugs in Australia, including those previously receiving HCV treatment. Methods: The ETHOS Engage study was an observational cohort study which collected self‐reported survey data on demographic and drug use information from people who inject drugs attending drug treatment clinics and needle and syringe programs over two waves between May 2018 and June 2021. Logistic regression was used to identify factors associated with needle/syringe sharing. Results: Overall, 1555/2395 people enrolled in ETHOS Engage (65%) injected drugs in the past month. Among these, 432 (28%) reported needle/syringe sharing in the past month and 276 (18%) reported receptive sharing. Factors associated with receptive sharing included younger age (adjusted odds ratio [aOR] 1.72; 95% confidence interval [CI] 1.28–2.30), recent incarceration (aOR 2.04; 95% CI 1.40–2.94), more frequent injecting (≥daily vs. less than weekly; aOR 2.59; 95% CI 1.75–3.84) and unstable housing (aOR 1.78; 95% CI 1.26–2.52). Among 560 participants with prior HCV treatment, 87 (16%) reported receptive sharing with younger age (aOR 2.42; 95% CI 1.45–4.05) and daily or greater injection frequency (aOR 2.51; 95% CI 1.31–4.83) associated with receptive sharing. Discussion and Conclusions: Needle/syringe sharing was common among this population accessing harm reduction services. This study identifies high‐risk populations with needle/syringe sharing. Research is needed to optimise HCV treatment to ensure people with ongoing risk behaviours receive adequate harm reduction following treatment to prevent reinfection. [ABSTRACT FROM AUTHOR]

Published
2024
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48. The Effect of Female Sex on Hepatitis C Incidence Among People Who Inject Drugs: Results From the International Multicohort InC3 Collaborative.

Author

Esmaeili, Aryan, Mirzazadeh, Ali, Morris, Meghan D, Hajarizadeh, Behzad, Sacks, Henry S, Maher, Lisa, Grebely, Jason, Kim, Arthur Y, Lauer, Georg, Cox, Andrea L, Hellard, Margaret, Dietze, Paul, Bruneau, Julie, Shoukry, Naglaa H, Dore, Gregory J, Lloyd, Andrew R, Prins, Maria, Page, Kimberly, and InC3 Collaborative

Subjects
InC3 Collaborative, Humans, Hepatitis C, Substance Abuse, Intravenous, Incidence, Risk Factors, Prospective Studies, Sex Factors, Adult, Female, Male, hepatitis C virus, incidence, people who inject drugs, sex, survival analysis, Emerging Infectious Diseases, Prevention, Liver Disease, Digestive Diseases, Hepatitis - C, HIV/AIDS, Infectious Diseases, Hepatitis, Chronic Liver Disease and Cirrhosis, 2.2 Factors relating to the physical environment, Aetiology, Infection, Good Health and Well Being, Biological Sciences, Medical and Health Sciences, Microbiology
Abstract

Background:The objective of this study was to assess differences in hepatitis C virus (HCV) incidence by sex in people who inject drugs (PWID), using a large international multicohort set of pooled biological and behavioral data from prospective observational studies of incident human immunodeficiency virus (HIV) and HCV infections in high-risk cohorts (the InC3 Collaborative). Methods:HCV infection date was estimated based on a hierarchy of successive serological (anti-HCV), virological (HCV RNA), and clinical (symptoms and/or liver function tests) data. We used a Cox proportional hazards model to calculate the crude and adjusted female to male (F:M) hazard ratio (HR) for HCV incidence using biological sex as the main exposure. Results:A total of 1868 PWID were observed over 3994 person-years of observation (PYO). Unadjusted F:M HR was 1.38 (95% confidence interval [CI], 1.15-1.65) and remained significant after adjusting for behavioral and demographic risk factors (1.39 [95% CI, 1.12-1.72]). Although syringe and equipment sharing were associated with the highest HCV incidence rate in women (41.62 and 36.83 PYO, respectively), we found no sex differences attributed to these risk factors. Conclusions:Our findings indicate that women who inject drugs may be at greater risk of HCV acquisition than men, independent of demographic characteristics and risk behaviors. Multiple factors, including biological (hormonal), social network, and differential access to prevention services, may contribute to increased HCV susceptibility in women who inject drugs.

Published
2018

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