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1. IgA Nephropathy in Children: A Multicenter Study in Poland

Author

Mizerska-Wasiak, M., Turczyn, A., Such, A., Cichoń-Kawa, K., Małdyk, J., Miklaszewska, M., Pietrzyk, J., Rybi-Szumińska, A., Wasilewska, A., Firszt-Adamczyk, A., Stankiewicz, R., Szczepańska, M., Bieniaś, B., Zajączkowska, M., Pukajło-Marczyk, A., Zwolińska, D., Siniewicz-Luzeńczyk, K., Tkaczyk, M., Gadomska-Prokop, K., Grenda, R., Demkow, U., Pańczyk-Tomaszewska, M., and Pokorski, Mieczyslaw, editor

Published
2016
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2. Increased Serum IgA in Children with IgA Nephropathy, Severity of Kidney Biopsy Findings and Long-Term Outcomes

Author

Mizerska-Wasiak, M., Małdyk, J., Pańczyk-Tomaszewska, M., Turczyn, A., Cichoń-Kawa, K., Rybi-Szumińska, A., Wasilewska, A., Firszt-Adamczyk, A., Stankiewicz, R., Bieniaś, B., Zajączkowska, M., Gadomska-Prokop, K., Grenda, R., Miklaszewska, M., Pietrzyk, J., Pukajło-Marczyk, Zwolińska, D., Szczepańska, M., Demkow, U., Roszkowska-Blaim, M., and Pokorski, Mieczyslaw, Series editor

Published
2015
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4. IgA Nephropathy in Children: A Multicenter Study in Poland

Author

Mizerska-Wasiak, M., primary, Turczyn, A., additional, Such, A., additional, Cichoń-Kawa, K., additional, Małdyk, J., additional, Miklaszewska, M., additional, Pietrzyk, J., additional, Rybi-Szumińska, A., additional, Wasilewska, A., additional, Firszt-Adamczyk, A., additional, Stankiewicz, R., additional, Szczepańska, M., additional, Bieniaś, B., additional, Zajączkowska, M., additional, Pukajło-Marczyk, A., additional, Zwolińska, D., additional, Siniewicz-Luzeńczyk, K., additional, Tkaczyk, M., additional, Gadomska-Prokop, K., additional, Grenda, R., additional, Demkow, U., additional, and Pańczyk-Tomaszewska, M., additional

Published
2016
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5. Proceedings of ESPGHAN Monothematic Conference 2020: 'acute Liver Failure in Children': Diagnosis and Initial Management

Author

Zellos, A. Debray, D. Indolfi, G. Czubkowski, P. Samyn, M. Hadzic, N. Gupte, G. Fischler, B. Smets, F. De Cléty, S.C. Grenda, R. Mozer, Y. Mancell, S. Jahnel, J. Auzinger, G. Worth, A. Lisman, T. Staufner, C. Baumann, U. Dhawan, A. Alonso, E. Squires, R.H. Verkade, H.J.

Abstract

Objectives:The Hepatology Committee of the European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) aims to educate pediatric gastroenterologists, members of ESPGHAN and professionals from other specialties promoting an exchange of clinical expertise in the field of pediatric hepatology. Herewith we have concentrated on detailing the recent advances in acute liver failure in infants and children.Methods:The 2020 ESPGHAN monothematic three-day conference on pediatric hepatology disease, entitled "acute liver failure" (ALF), was organized in Athens, Greece. ALF is a devastating disease with high mortality and most cases remain undiagnosed. As knowledge in diagnosis and treatment of ALF in infants and children has increased in the past decades, the objective was to update physicians in the field with the latest research and developments in early recognition, curative therapies and intensive care management, imaging techniques and treatment paradigms in these age groups.Results:In the first session, the definition, epidemiology, various causes of ALF, in neonates and older children and recurrent ALF (RALF) were discussed. The second session was dedicated to new aspects of ALF management including hepatic encephalopathy (HE), coagulopathy, intensive care interventions, acute on chronic liver failure, and the role of imaging in treatment and prognosis. Oral presentations by experts in various fields are summarized highlighting key learning points.Conclusions:The current report summarizes the major learning points from this meeting. It also identifies areas where there is gap of knowledge, thereby identifying the research agenda for the near future. © 2022 Lippincott Williams and Wilkins. All rights reserved.

Published
2022

8. Interfamilial clinical variability in four Polish families with cranioectodermal dysplasia and identical compound heterozygous variants in WDR35

Author

Walczak-Sztulpa, J., Wawrocka, A., Stańczyk, M., Pesz, K., Dudarewicz, L., Chrul, S., Bukowska-Olech, E., Wieczorek-Cichecka, N., Arts, H.H., Oud, M.M., Śmigiel, R., Grenda, R., Obersztyn, E., Chrzanowska, K.H., Latos-Bieleńska, A., Walczak-Sztulpa, J., Wawrocka, A., Stańczyk, M., Pesz, K., Dudarewicz, L., Chrul, S., Bukowska-Olech, E., Wieczorek-Cichecka, N., Arts, H.H., Oud, M.M., Śmigiel, R., Grenda, R., Obersztyn, E., Chrzanowska, K.H., and Latos-Bieleńska, A.

Abstract

Contains fulltext : 231678.pdf (Publisher’s version ) (Closed access)

Published
2021

14. Early proteinuria lowering by angiotensin-converting enzyme inhibition predicts renal survival in children with CKD

Author

Van Den Belt S.M., Heerspink H.J.L., Gracchi V., De Zeeuw D., Wühl E., Schaefer F., Anarat A., Bakkaloglu A., Ozaltin F., Peco-Antic A., Querfeld U., Gellermann J., Sallay P., Drozdz D., Bonzel K.-E., Wingen A.-M., Zurowska A., Balasz I., Trivelli A., Perfumo F., Müller-Wiefel D.E., Möller K., Offner G., Enke B., Gimpel C., Mehls O., Emre S., Caliskan S., Mir S., Wygoda S., Hohbach-Hohenfellner K., Jeck N., Klaus G., Ardissino G., Testa S., Montini G., Charbit M., Niaudet P., Caldas-Afonso A., Fernandes-Teixeira A., Dušek J., Matteucci M.C., Picca S., Mastrostefano A., Wigger M., Berg U.B., Celsi G., Fischbach M., Terzic J., Fydryk J., Urasinski T., Coppo R., Peruzzi L., Arbeiter K., Jankauskiené A., Grenda R., Litwin M., Janas R., Laube G., Neuhaus T.J., Çukurova Üniversitesi, Çocuk Sağlığı ve Hastalıkları, Ege Üniversitesi, Groningen Kidney Center (GKC), and Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET)

Subjects
Male, Medizin, 030232 urology & nephrology, Angiotensin-Converting Enzyme Inhibitors, Blood Pressure, Kaplan-Meier Estimate, 030204 cardiovascular system & hematology, urologic and male genital diseases, 0302 clinical medicine, Ramipril, Medicine, Child, Proteinuria, biology, Hazard ratio, General Medicine, Prognosis, female genital diseases and pregnancy complications, Survival Rate, ComputingMilieux_MANAGEMENTOFCOMPUTINGANDINFORMATIONSYSTEMS, Treatment Outcome, Nephrology, Area Under Curve, Child, Preschool, Disease Progression, Female, InformationSystems_MISCELLANEOUS, medicine.symptom, Glomerular Filtration Rate, medicine.drug, medicine.medical_specialty, Adolescent, Urology, Renal function, Risk Assessment, 03 medical and health sciences, Clinical Research, Confidence Intervals, Humans, Proportional Hazards Models, business.industry, ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS, Angiotensin-converting enzyme, Confidence interval, ComputingMethodologies_PATTERNRECOGNITION, Concomitant, Multivariate Analysis, Linear Models, biology.protein, Kidney Failure, Chronic, business, Renal survival
Abstract

PubMed ID: 29930161, Background Although pharmacotherapeutic proteinuria lowering was found to be nephroprotective in adults, the predictive value of early drug-induced proteinuria reduction for long-term renal survival in pediatric CKD is unknown. We analyzed data from the ESCAPE Trial for a potential association between initial antiproteinuric effect of standardized angiotensin-converting enzyme (ACE) inhibition and renal disease progression in children with CKD. Methods In total, 280 eligible children with CKD stages 2-4 (mean age 11.7 years old, median eGFR 46 ml/min per 1.73 m2, 71% congenital renal malformations) received a fixed dose of ramipril (6 mg/m2 per day) and were subsequently randomized to conventional or intensified BP control. We assessed initial proteinuria reduction from baseline to first measurement on ramipril (at 2.561.3 months). We used multivariable Cox modeling to estimate the association between initial proteinuria reduction and the risk of reaching a renal end point (50% eGFR decline or ESRD), which occurred in 80 patients during 5 years of observation. Results Ramipril therapy lowered proteinuria by a mean of 43.5% (95% confidence interval, 36.3% to 49.9%). Relative to proteinuria reduction,30%, 30%-60% and .60% reduction resulted in hazard ratios (95% confidence intervals) of 0.70 (0.40 to 1.22) and 0.42 (0.22 to 0.79), respectively. This association was independent of age, sex, CKD diagnosis, baseline eGFR, baseline proteinuria, initial BP, and concomitant BP reduction. Conclusions The early antiproteinuric effect of ACE inhibition is associated with long-term preservation of renal function in children with CKD. Proteinuria lowering should be considered an important target in the management of pediatric CKD. Copyright © 2018 by the American Society of Nephrology., Baxter Nederland Fifth Framework Programme: QLRT-2001-00908 Boehringer Ingelheim Stiftung Cancer Research Foundation European Commission American College of Endocrinology, The Effect of Strict Blood Pressure Control and ACE inhibition on the Progression of CRF in Pediatric Patients (ESCAPE) Trial was supported by grants from the Boehringer Ingelheim Stiftung, the European Commission (Fifth Framework Programme QLRT-2001-00908), the Kuratorium für Dialyse und Nierentransplantation e.V., Neu-Isenburg, and the Baxter Extramural Grant Program. Aventis Pharmaceuticals supplied ramipril and financed the Good Clinical Practice audit.

Published
2018

18. Combined Liver-Kidney Transplantation in Children: Single-Center Experiences and Long-Term Results

Author

Szymczak, M., primary, Kaliciński, P., additional, Kowalewski, G., additional, Markiewicz-Kijewska, M., additional, Broniszczak, D., additional, Ismail, H., additional, Stefanowicz, M., additional, Kowalski, A., additional, Rubik, J., additional, Jankowska, I., additional, Piątosa, B., additional, Teisseyre, J., additional, and Grenda, R., additional

Published
2018
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19. Estimating Time to ESRD in Children With CKD

Author

Furth, Susan L., primary, Pierce, Chris, additional, Hui, Wun Fung, additional, White, Colin A., additional, Wong, Craig S., additional, Schaefer, Franz, additional, Wühl, Elke, additional, Abraham, Alison G., additional, Warady, Bradley A., additional, Samuels, Joshua, additional, Furth, Susan, additional, Atkinson, Meredith, additional, Wilson, Amy, additional, Quiroga, Alejandro, additional, Massengill, Susan, additional, Selewski, Dave, additional, Ferris, Maria, additional, Kogon, Amy, additional, Kaskel, Frederick, additional, Lande, Marc, additional, Schwartz, George, additional, Saland, Jeffrey, additional, Norwood, Victoria, additional, Matoo, Tej, additional, Hidalgo, Guillermo, additional, Srivaths, Poyyapakkam, additional, Carlson, Joann, additional, Langman, Craig, additional, Mendley, Susan, additional, John, Eunice, additional, Upadhyay, Kiran, additional, Seo-Mayer, Patricia, additional, Patterson, Larry, additional, Parekh, Rulan, additional, Robinson, Lisa, additional, Weinstein, Adam, additional, Samsonov, Dmitry, additional, Kupferman, Juan, additional, Misurac, Jason, additional, Mongia, Anil, additional, Kiessling, Steffan, additional, Sanchez-Kazi, Cheryl, additional, Dart, Allison, additional, Fathallah, Sahar, additional, Claes, Donna, additional, Mitsnefes, Mark, additional, Blydt-Hansen, Tom, additional, Warady, Bradley, additional, Greenbaum, Larry, additional, Flynn, Joseph, additional, Wong, Craig, additional, Salusky, Isidro, additional, Yadin, Ora, additional, Dell, Katherine, additional, Jenkins, Randall, additional, Pan, Cynthia, additional, Ku, Elaine, additional, Al-Uzri, Amira, additional, Rodig, Nancy, additional, Wong, Cynthia, additional, Davis, Keefe, additional, Turman, Martin, additional, Bartosh, Sharon, additional, Hastings, Colleen, additional, Nayak, Anjali, additional, Seikaly, Mouin, additional, Benador, Nadine, additional, Mak, Robert, additional, Wood, Ellen, additional, Lerner, Gary, additional, Barletta, Gina Marie, additional, Anarat, A., additional, Bakkaloglu, A., additional, Ozaltin, F., additional, Peco-Antic, A., additional, Querfeld, U., additional, Gellermann, J., additional, Sallay, P., additional, Drożdż, D., additional, Bonzel, K.-E., additional, Wingen, A.-M., additional, Żurowska, A., additional, Balasz, I., additional, Trivelli, A., additional, Perfumo, F., additional, Müller-Wiefel, D.E., additional, Möller, K., additional, Offner, G., additional, Enke, B., additional, Wühl, E., additional, Hadtstein, C., additional, Mehls, O., additional, Schaefer, F., additional, Emre, S., additional, Caliskan, S., additional, Mir, S., additional, Wygoda, S., additional, Hohbach-Hohenfellner, K., additional, Jeck, N., additional, Klaus, G., additional, Ardissino, G., additional, Testa, S., additional, Montini, G., additional, Charbit, M., additional, Niaudet, P., additional, Caldas-Afonso, A., additional, Fernandes-Teixeira, A., additional, Dušek, J., additional, Matteucci, M.C., additional, Picca, S., additional, Mastrostefano, A., additional, Wigger, M., additional, Berg, U.B., additional, Celsi, G., additional, Fischbach, M., additional, Terzic, J., additional, Fydryk, J., additional, Urasinski, T., additional, Coppo, R., additional, Peruzzi, L., additional, Arbeiter, K., additional, Jankauskiené, A., additional, Grenda, R., additional, Litwin, M., additional, Janas, R., additional, and Neuhaus, T.J., additional

Published
2018
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20. Normal 25-Hydroxyvitamin D Levels Are Associated with Less Proteinuria and Attenuate Renal Failure Progression in Children with CKD

Author

Shroff R., Aitkenhead H., Costa N., Trivelli A., Litwin M., Picca S., Anarat A., Sallay P., Ozaltin F., Zurowska A., Jankauskiene A., Montini G., Charbit M., Schaefer F., Wühl E., Bakkaloglu A., Peco-Antic A., Querfeld U., Gellermann J., Drozdz D., Bonzel K.-E., Wingen A.-M., Balasz I., Perfumo F., Müller-Wiefel D.E., Möller K., Offner G., Enke B., Gimpel C., Mehls O., Emre S., Caliskan S., Mir S., Wygoda S., Hohbach-Hohenfellner K., Jeck N., Klaus G., Ardissino G., Testa S., Niaudet P., Caldas-Afonso A., Fernandes-Teixeira A., Duek J., Matteucci M.C., Mastrostefano A., Wigger M., Berg U.B., Celsi G., Fischbach M., Terzic J., Fydryk J., Urasinski T., Coppo R., Peruzzi L., Arbeiter K., Jankauskiené A., Grenda R., Janas R., Laube G., Neuhaus T.J., Çukurova Üniversitesi, Çocuk Sağlığı ve Hastalıkları, and Ege Üniversitesi

Subjects
Male, Vitamin, medicine.medical_specialty, Adolescent, Medizin, 030232 urology & nephrology, Diastole, Renal function, Angiotensin-Converting Enzyme Inhibitors, 030204 cardiovascular system & hematology, urologic and male genital diseases, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Clinical Research, Reference Values, Internal medicine, Renin–angiotensin system, medicine, Vitamin D and neurology, Humans, Renal Insufficiency, Renal Insufficiency, Chronic, Vitamin D, Child, Klotho, Retrospective Studies, Creatinine, Proteinuria, business.industry, ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS, General Medicine, Urology & Nephrology, ComputingMilieux_MANAGEMENTOFCOMPUTINGANDINFORMATIONSYSTEMS, Fibroblast Growth Factor-23, ComputingMethodologies_PATTERNRECOGNITION, Endocrinology, chemistry, Nephrology, Disease Progression, Female, InformationSystems_MISCELLANEOUS, medicine.symptom, business
Abstract

PubMed ID: 26069294, Angiotensin-converting enzyme inhibitors (ACEi) for renin-angiotensin-aldosterone system (RAAS) blockade are routinely used to slow CKD progression. However, Vitamin D may also promote renoprotection by suppressing renin transcription through cross-talk between RAAS and Vitamin D -fibroblast growth factor-23 (FGF-23)-Klotho pathways. To determine whether Vitamin D levels influence proteinuria and CKD progression in children, we performed a post hoc analysis of the Effect of Strict Blood Pressure Control and ACE Inhibition on Progression of CKD in Pediatric Patients (ESCAPE) cohort. In 167 children (median EGFR 51 ml/min per 1.73 m2), serum 25-hydroxyvitaminD(25(OH)D),FGF-23, andKlotho levelsweremeasuredatbaselineandafteramedian8months onACEi.Childrenwith lower 25(OH)D levels had higher urinary protein/creatinine ratios at baseline (P=0.03) and at follow-up (P=0.006). Levels of 25(OH)D and serum Vitamin D -binding protein were not associated, but 25(OH)D #50 nmol/L associated with higher diastolicBP(P=0.004).ACEi therapy alsoassociatedwith increasedKlotho levels (P

Published
2016

25. Characteristics of Potential Living Kidney Donors and Recipients: Donor Disqualification Reasons—Experience of a Polish Center

Author

Gozdowska, J., primary, Jankowski, K., additional, Bieniasz, M., additional, Wszoła, M., additional, Domagała, P., additional, Kieszek, R., additional, Lewandowska, D., additional, Urbanowicz, A., additional, Szmidt, J., additional, Grenda, R., additional, Kwiatkowski, A., additional, Chmura, A., additional, and Durlik, M., additional

Published
2013
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26. The CERTAIN Registry: A Novel, Web-Based Registry and Research Platform for Pediatric Renal Transplantation in Europe

Author

Plotnicki, L., primary, Kohl, C.D., additional, Höcker, B., additional, Krupka, K., additional, Rahmel, A., additional, Pape, L., additional, Hoyer, P., additional, Marks, S.D., additional, Webb, N.J.A., additional, Söylemezoglu, O., additional, Topaloglu, R., additional, Szabo, A.J., additional, Seeman, T., additional, Marlies Cornelissen, E.A., additional, Knops, N., additional, Grenda, R., additional, and Tönshoff, B., additional

Published
2013
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28. The CERTAIN Registry: A Novel, Web-Based Registry and Research Platform for Paediatric Renal Transplantation in Europe

Author

Plotnicki, L., primary, Höcker, B., additional, Krupka, K., additional, Kohl, C., additional, Rahmel, A., additional, Pape, L., additional, Hoyer, P., additional, Marks, S. D., additional, Webb, N., additional, Söylemezoglu, O., additional, Topaloglu, R., additional, Szabó, A., additional, Seeman, T., additional, Cornelissen, E. A.M., additional, Knops, N., additional, Grenda, R., additional, and Tönshoff, B., additional

Published
2012
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30. Paediatric nephrology

Author

Klein, J., primary, Lacroix, C., additional, Caubet, C., additional, Siwy, J., additional, Muller, F., additional, Bascands, J.-L., additional, Decramer, S., additional, Schanstra, J., additional, Camilla, R., additional, Loiacono, E., additional, Peruzzi, L., additional, Gallo, R., additional, Donadio, M. E., additional, Vergano, L., additional, Campolo, F., additional, Morando, L., additional, Amore, A., additional, Coppo, R., additional, Dossier, C., additional, Leclerc, A.-L., additional, Lapidus, N., additional, Rousseau, A., additional, Charbit, M., additional, Sarda, H., additional, Madhi, F., additional, Carrat, F., additional, Deschenes, G., additional, Harambat, J., additional, Dallocchio, A., additional, Guigonis, V., additional, Ichay, L., additional, Bessenay, L., additional, Broux, F., additional, Garnier, A., additional, Morin, D., additional, Llanas, B., additional, Saint-Marcoux, F., additional, Van Stralen, K., additional, Verrina, E., additional, Belingheri, M., additional, Dusek, J., additional, Dudley, J., additional, Grenda, R., additional, Rubik, J., additional, Rudaitis, S., additional, Rudin, C., additional, Schaefer, F., additional, Jager, K., additional, Loos, S., additional, and Kemper, M. J., additional

Published
2012
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32. 353 The Vntr Il1Rn Gene Polymorphism in Polish Children with Diffuse Mesangial Proliferation (DMP)

Author

Skonieczna, K, primary, Marciniak, H, additional, Bińczak-Kuleta, A, additional, Drożdżyńska, M, additional, Krysztalowska, M, additional, Peregud-Pogorzelski, J, additional, Litwin, M, additional, Grenda, R, additional, Panczyk-Tomaszewska, M, additional, Roszkowska-Blaim, M, additional, Brodkiewicz, A, additional, and Ciechanowicz, A, additional

Published
2010
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34. Technology Needs Assessment of an Atmospheric Observation System for Multidisciplinary Air Quality/Meteorology Missions, Part 2

Author

Alvarado, U. R, Bortner, M. H, Grenda, R. N, Brehm, W. F, Frippel, G. G, Alyea, F, Kraiman, H, Folder, P, and Krowitz, L

Subjects
Environment Pollution
Abstract

The technology advancements that will be necessary to implement the atmospheric observation systems are considered. Upper and lower atmospheric air quality and meteorological parameters necessary to support the air quality investigations were included. The technology needs were found predominantly in areas related to sensors and measurements of air quality and meteorological measurements.

Published
1982

35. Technology needs assessment of an atmospheric observation system for tropospheric research missions, part 1

Author

Alvarado, D. R, Bortner, M. H, Grenda, R. N, Frippel, G. G, Halsey, H, Neste, S. L, Kritikos, H, Keafer, L. S, and Deryder, L. J

Subjects
Environment Pollution
Abstract

The technology advancements needed to implement the atmospheric observation satellite systems for air quality research were identified. Tropospheric measurements are considered. The measurements and sensors are based on a model of knowledge objectives in atmospheric science. A set of potential missions and attendant spacecraft and sensors is postulated. The results show that the predominant technology needs will be in passive and active sensors for accurate and frequent global measurements of trace gas concentration profiles.

Published
1982

36. The measurement of carbon monoxide and methane in the national capital air quality control region. III - Correlation interferometer results

Author

Goldstein, H. W, Bortner, M. H, Grenda, R. N, Dick, R, Lebel, P. J, and Lamontagne, R. A

Subjects
Environment Pollution
Abstract

Two types of experiments were performed with a correlation interferometer on-board a Bell Jet Ranger 206 Helicopter. The first consisted of simultaneous ground- and air-truth measurements as the instrumented helicopter passed over the Cheverly site. The second consisted of several measurement flights in and around the national capital air quality control region (Washington, D.C.). The correlation interferometer data, the infrared Fourier spectrometer data, and the integrated altitude sampling data showed agreement within the errors of the individual measurements. High values for CO were found from the D.C. flight data to be reproducible and concentrated in areas of stop-and-go traffic. It is concluded, that pollutants at low altitudes are detectable from an air-borne platform by remote correlation interferometry and that the correlation interferometer measurements agree with ground- and air-truth data.

Published
1976

37. Carbon monoxide pollution experiment

Author

Bortner, M. H, Dick, R, Goldstein, H. W, and Grenda, R. N

Subjects
Environment Pollution
Abstract

The experiment is designed to obtain data for the investigation of mechanisms by which CO is removed from the earth's atmosphere. The approach uses an orbiting platform to remotely map global CO concentrations and determine vertical CO profiles using a correlation interferometer measurement technique. The instrument is capable of measuring CO over the range of expected atmospheric burdens and of measuring trace atmospheric constituents.

Published
1975

39. CIMATS - A correlation interferometer for the measurement of atmospheric trace species

Author

Goldstein, H. W, Grenda, R. N, Bortner, M. H, and Dick, R

Subjects
Instrumentation And Photography
Abstract

A multigas correlation interferometer, based on the previously developed and tested COPE instrument, has been designed and fabricated and is presently undergoing laboratory testing. The CIMATS instrument has the capability to remotely measure densities of selected gaseous atmospheric species in the spectral range 2 to 2.5 and 4 to 10 microns. The sensor has been designed for both nadir viewing and earth limb viewing. As presently configured the sensor is capable of measuring ammonia, nitrous oxide, and carbon monoxide in the nonthermal infrared spectral region and carbon monoxide and sulfur dioxide in the thermal infrared. Other gaseous species can be measured by inclusion of additional narrow band filters.

Published
1978

40. A study of selected environmental quality remote sensors for free flyer missions launched from the space shuttle

Author

Goldstein, H. W and Grenda, R. N

Subjects
Earth Resources And Remote Sensing
Abstract

The sensors were examined for adaptability to shuttle by reviewing pertinent information regarding sensor characteristics as they related to the shuttle and Multimission Modular Spacecraft environments. This included physical and electrical characteristics, data output and command requirements, attitude and orientation requirements, thermal and safety requirements, and adaptability and modification for space. The sensor requirements and characteristics were compared with the corresponding shuttle and Multimission Modular Spacecraft characteristics and capabilities. On this basis the adaptability and necessary modifications for each sensor were determined. A number of the sensors were examined in more detail and estimated cost for the modifications was provided.

Published
1977

44. Carbon monoxide pollution experiment. I - A solution to the carbon monoxide sink anomaly.

Author

Grenda, R. N, Bortner, M. H, Lebel, P. J, Davies, J. H, and Dick, R

Subjects
Instrumentation And Photography
Abstract

The observed lack of a high rate of growth in global CO concentration implies that there is some sink mechanism for destroying the CO as rapidly as it is being produced. A program is described which is intended to develop both the experiment concept and the remote sensor required to measure atmospheric CO with sufficient accuracy to locate the sink, whether it be at the earth's surface or in the upper atmosphere. The program calls for the development of a remote sensor which can look for surface sinks by mapping the vertical CO burden in the atmosphere on a daily basis, and which can look for an upper atmospheric sink by means of measurements of total CO in a horizontal path through the limb of the earth's atmosphere, using the sun as the source.

Published
1971

45. Meteoroid hazards in deep space Final report

Author

Chaess, H, Chandra, S, Grenda, R, Lambert, R, Neste, S, Rutter, B, Shaffer, W, and Soberman, R

Subjects
Space Vehicles
Abstract

Design and development of Sisyphus meteoroid detection system for interplanetary spacecraft

Published
1968

46. Analysis of the feasibility of an experiment to measure carbon monoxide in the atmosphere

Author

Bortner, M. H, Alyea, F. N, Grenda, R. N, Liebling, G. R, and Levy, G. M

Subjects
Chemistry
Abstract

The feasibility of measuring atmospheric carbon monoxide from a remote platform using the correlation interferometry technique was considered. It has been determined that CO data can be obtained with an accuracy of 10 percent using this technique on the first overtone band of CO at 2.3 mu. That band has been found to be much more suitable than the stronger fundamental band at 4.6 mu. Calculations for both wavelengths are presented which illustrate the effects of atmospheric temperature profiles, inversion layers, ground temperature and emissivity, CO profile, reflectivity, and atmospheric pressure. The applicable radiative transfer theory on which these calculations are based is described together with the principles of the technique.

Published
1973

47. Correlation interferometric measurement of trace species in the atmosphere.

Author

Goldstein, H. W, Bortner, M. H, Grenda, R. N, Karger, A. M, and Lebel, P. J

Subjects
Geophysics
Abstract

Two correlation interferometers, a breadboard model and an engineering model, have been designed, constructed, and tested for the measurement of selected atmospheric trace species. Test results showed that errors of less than 10% are attainable for atmospheric amounts of carbon monoxide and methane measured at 2.3 microns. Based on these results a program has been undertaken to determine the feasibility of measuring other trace species by correlation interferometry. It shown that in addition to carbon monoxide and methane, carbon dioxide, water vapor, ammonia, nitric oxide, nitrous oxide, nitrogen dioxide, and sulfur dioxide can also be accurately measured with this instrument.

Published
1973

48. Development of a breadboard model correlation interferometer for the carbon monoxide pollution experiment

Author

Bortner, M. H, Dick, R, Goldstein, H. W, Grenda, R. N, and Levy, G. M

Subjects
Instrumentation And Photography
Abstract

The breadboard model of the correlation interferometer for the Carbon Monoxide Pollution Experiment has been designed, fabricated, and tested. Laboratory, long-path, and atmospheric tests which were performed show the technique to be a feasible method for obtaining a global carbon monoxide map and a vertical carbon monoxide profile and similar information is readily obtainable for methane as well. In addition, the technique is readily applicable to other trace gases by minor instrumental changes. As shown by the results and the conclusions, it has been determined that CO and CH4 data can be obtained with an accuracy of 10% using this technique on the spectral region around 2.3 microns.

Published
1973

49. The remote measurement of trace atmospheric species by correlation interferometry. I - Carbon monoxide and methane

Author

Goldstein, H. W, Bortner, M. H, Grenda, R. N, Karger, A. M, Dick, R, David, F, and Lebel, P. J

Subjects
Instrumentation And Photography
Abstract

A correlation interferometer has been developed for the measurement of carbon monoxide and methane at 2.35 micrometers in the troposphere and in the stratosphere. This instrument has been tested in laboratory tests, solar-looking outdoor tests, and downward-looking airplane-based tests. The aircraft tests were flown on a Falcon fanjet provided by The Canada Centre for Remote Sensing over both polluted and unpolluted regions of North America. The results of these various tests are discussed. Based on the results obtained for carbon monoxide and methane, a study was undertaken to investigate the feasibility of measuring other atmospheric trace species by correlation interferometry. Results of the feasibility study for carbon dioxide, water vapor, ammonia, nitrous oxide, nitric oxide, nitrogen dioxide, sulfur dioxide, and several hydrocarbons are presented.

Published
1973

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