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2. Patients’ and caregivers’ perception of multidimensional and palliative care in amyotrophic lateral sclerosis – protocol of a German multicentre study

Author

Linse, Katharina, Weber, Constanze, Reilich, Peter, Schöberl, Florian, Boentert, Matthias, Petri, Susanne, Rödiger, Annekathrin, Posa, Andreas, Otto, Markus, Wolf, Joachim, Zeller, Daniel, Brunkhorst, Robert, Koch, Jan, Hermann, Andreas, Großkreutz, Julian, Schröter, Carsten, Groß, Martin, Lingor, Paul, Machetanz, Gerrit, Semmler, Luisa, Dorst, Johannes, Lulé, Dorothée, Ludolph, Albert, Meyer, Thomas, Maier, André, Metelmann, Moritz, Regensburger, Martin, Winkler, Jürgen, Schrank, Berthold, Kohl, Zacharias, Hagenacker, Tim, Brakemeier, Svenja, Weyen, Ute, Weiler, Markus, Lorenzl, Stefan, Bublitz, Sarah, Weydt, Patrick, Grehl, Torsten, Kotterba, Sylvia, Lapp, Hanna-Sophie, Freigang, Maren, Vidovic, Maximilian, Aust, Elisa, and Günther, René

Published
2024
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3. Middle-mile optimization for next-day delivery

Author

Benidis, Konstantinos, Paschos, Georgios, Gross, Martin, and Iosifidis, George

Subjects
Computer Science - Data Structures and Algorithms
Abstract

We consider an e-commerce retailer operating a supply chain that consists of middle- and last-mile transportation, and study its ability to deliver products stored in warehouses within a day from customer's order time. Successful next-day delivery requires inventory availability and timely truck schedules in the middle-mile and in this paper we assume a fixed inventory position and focus on optimizing the middle-mile. We formulate a novel optimization problem which decides the departure of the last middle-mile truck at each (potential) network connection in order to maximize the number of next-day deliveries. We show that the respective \emph{next-day delivery optimization} is a combinatorial problem that is $NP$-hard to approximate within $(1-1/e)\cdot\texttt{opt}\approx 0.632\cdot\texttt{opt}$, hence every retailer that offers one-day deliveries has to deal with this complexity barrier. We study three variants of the problem motivated by operational constraints that different retailers encounter, and propose solutions schemes tailored to each problem's properties. To that end, we rely on greedy submodular maximization, pipage rounding techniques, and Lagrangian heuristics. The algorithms are scalable, offer optimality gap guarantees, and evaluated in realistic datasets and network scenarios were found to achieve near-optimal results.

Published
2023

7. 5qSMA: standardised retrospective natural history assessment in 268 patients with four copies of SMN2

Author

Vill, Katharina, Tacke, Moritz, König, Anna, Baumann, Matthias, Baumgartner, Manuela, Steinbach, Meike, Bernert, Guenther, Blaschek, Astrid, Deschauer, Marcus, Flotats-Bastardas, Marina, Friese, Johannes, Goldbach, Susanne, Gross, Martin, Günther, René, Hahn, Andreas, Hagenacker, Tim, Hauser, Erwin, Horber, Veronka, Illsinger, Sabine, Johannsen, Jessika, Kamm, Christoph, Koch, Jan C., Koelbel, Heike, Koehler, Cornelia, Kolzter, Kirsten, Lochmüller, Hanns, Ludolph, Albert, Mensch, Alexander, Meyer zu Hoerste, Gerd, Mueller, Monika, Mueller-Felber, Wolfgang, Neuwirth, Christoph, Petri, Susanne, Probst-Schendzielorz, Kristina, Pühringer, Manuel, Steinbach, Robert, Schara-Schmidt, Ulrike, Schimmel, Mareike, Schrank, Bertold, Schwartz, Oliver, Schlachter, Kurt, Schwerin-Nagel, Annette, Schreiber, Gudrun, Smitka, Martin, Topakian, Raffi, Trollmann, Regina, Tuerk, Matthias, Theophil, Manuela, Rauscher, Christian, Vorgerd, Mathias, Walter, Maggie C., Weiler, Markus, Weiss, Claudia, Wilichowski, Ekkehard, Wurster, Claudia D., Wunderlich, Gilbert, Zeller, Daniel, Ziegler, Andreas, Kirschner, Janbernd, and Pechmann, Astrid

Published
2024
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8. Efficacy and safety of gene therapy with onasemnogene abeparvovec in children with spinal muscular atrophy in the D-A-CH-region: a population-based observational study

Author

Baum, Petra, Baumgartner, Manuela, Bertsche, Astrid, Blankenburg, Markus, Denecke, Jonas, Deschauer, Marcus, Eckenweiler, Matthias, Geis, Tobias, Goldhahn, Klaus, Groß, Martin, Günther, René, Hagenacker, Tim, Hamelmann, Eckard, Husain, Ralf A., Kamm, Christoph, Kauffmann, Birgit, Koch, Jan Christoph, Löscher, Wolfgang, Ludolph, Albert, Martin, Pascal, Mensch, Alexander, Meyer zu Hörste, Gerd, Neuwirth, Christoph, Petri, Susanne, Pühringer, Manuel, Rathmann, Imke, Schäfer, Dorothee, Schimmel, Mareike, Schrank, Bertold, Schreiber-Katz, Olivia, Schwerin-Nagel, Anette, Smitka, Martin, Steinbach, Meike, Steiner, Elisabeth, Stoffels, Johannes, Theophil, Manuela, Topakian, Raffi, Türk, Matthias, Vorgerd, Matthias, Walter, Maggie C., Weiler, Markus, Wiegand, Gert, Wunderlich, Gilbert, Wurster, Claudia Diana, Zeller, Daniel, Metelmann, Moritz, Zeiner, Fiona, Pilshofer, Veronika, Rappold, Mika, Pauschek, Josefine, Reihle, Christof, Homma, Annette Karolin, Lingor, Paul, Henzi, Bettina, Reinhardt, Tabea, Holzwarth, Dorothea, Wittmann, Wolfgang, Kappel, Stefan, Freigang, Maren, Stolte, Benjamin, Martakis, Kyriakos, Classen, Georg, Roland-Schäfer, Doris, Steuernagel, Daniela, Hartmann, Hans, Fischer, Sophie, Wermuth, Marieke, Muhandes, Mohamad Tareq, Hotter, Anna, Uzelac, Zeljko, Naegel, Steffen, Wiethoff, Sarah, Braun, Nathalie, Bjelica, Bogdan, Kölbel, Heike, Angelova-Toshkina, Daniela, Wilken, Bernd, Osmanovic, Alma, Fiedler, Barbara, Plecko, Barbara, Tomforde, Maike, Voelkl, Thomas, von Moers, Arpad, Müller, Petra, Behring, Bettina, Güttsches, Anne, Reilich, Peter, Wick, Wolfgang, Stoltenburg, Corinna, Witzel, Simon, Bellut, Julia, Hoffmann, Georg Friedrich, Mörtlbauer, Kathrin, Ille, Alexandra, Schroth, Michael, Driemeyer, Joenna, Semmler, Luisa, Müller, Cornelia, Dörnbrack, Katharina, Zemlin, Michael, Geitmann, Stephanie, Lapp, Hanna Sophie, Brakemeier, Svenja, Gehrke, Tascha, Ntemiris, Klearchos, Kaiser, Nadja, Borowski, Sabine, Ramadan, Barbara, Hustedt, Ulf, Baum, Tobias, Schneider, Ilka, Akova-Oztürk, Esra, Vill, Katharina, Dibrani, Zylfie, Wohnrade, Camilla, Della-Marina, Adela, Jung, Lisa, Deba, Timo, Zobel, Joachim, Schallner, Jens, Kraut, Christina, Vollmann, Peter, Schüssler, Stephanie, Roeder, Melanie, Hiebeler, Miriam, Berberich, Nicole, Schneider, Joanna, Brauner, Brigitte, Kölker, Stefan, Pernegger, Elke, Gosk-Tomek, Magdalena, Braun, Sarah, Weiss, Deike, Machetanz, Gerrit, Langer, Thorsten, Saier, Christina, Baumann, Sandra, Hettrich, Sabine, Dworschak, Gabriel, Müller-Kaempffer, Katharina, Dittes, Isabelle, Thimm, Andreas, Quinten, Lisa, Albers, Kristina, Bevot, Andrea, Bretschneider, Christa, Dorst, Johannes, Kendzierski, Thomas, Hannibal, Iris, Bischofberger, Jasmin, Riesmeier, Tilman, Gangfuß, Andrea, Johann to Settel, Eva, Grässl, Michael, Fiebig, Susan, Hollerauer, Carmen, Seeber, Lea, Krahwinkler, Ina, Lange, Irene, Montagnese, Federica, Mann-Richter, Marcel, Wagner, Alexandra, Leypold, Christine, Saffari, Afshin, Anna, Elmecker, Wiesenhofer, Anna, Wendel, Eva-Maria, Steffens, Paula-Sophie, Wider, Sabine, Tassoni, Adrian, Dall, Andrea, Busch, Franziska, Zeisler, Daniela, Wessel, Maria, Lipka, Jaqueline, Hackemer, Andrea, Plugge, Loreen, Jansen, Eva, Roth, Erdmute, Schuster, Joachim, Koelsch, Anna, Warken-Madelung, Birgit, Schwippert, Michaela, Holtkamp, Britta, Köbbing, Katja, Claeys, Sander, Foerster, Sandy, Thiele, Simone, Rochau-Trumpp, Heidi, George, Annette, Niesert, Moritz, Neimair, Tanja, Vettori, Katia, Haverkamp, Julia, Taherpour, Jila, Hug, Juliane, Wenzel, Franziska, Bant, Christina, Baur, Ute, Bühner, Kathrin, Schlag, Melina, Ruß, Lena, Küpper, Hanna, Müller, Anja, Wollinsky, Kurt, Well, Therese, Leinert, Antonia, Andres, Barbara, Omran, Heymut, Claus, Nicole, Hagenmeyer, Anna, Schnurr, Marion, Dukic, Vladimir, Ludolph, Albert Christian, Specht, Sabine, Angermair, Verena, Hüpper, Anna, Banholzer, Daniela, Stein, Sabine, Kampowski, Tim, Richmann, Marion, Nicolai, Sylke, Atta, Omar, Meßmer, Birgit, de Vries, Heike, Rotenfusser, Elisabeth, Oscmanovic, Alma, Renger, Isabelle, Guillemot, Hélène, Lehnert, Ilka, Grünwedel, Mike, Grimm, Laura, Stocker, Guido, Kaindl, Angela M., Hoevel, Annegret, Stadler, Theresa, Fischer, Michal, Vogt, Sibylle, Gebert, Axel, Goldbach, Susanne, Kirschner, Janbernd, Lochmüller, Hanns, Müller-Felber, Wolfgang, Pechmann, Astrid, Schara-Schmidt, Ulrike, Probst-Schendzielorz, Kristina, Lang, Annina, Nitzsche, Maren, Hammer, Julie, Müller-Kaempfer, Katharina, Wirner-Piotrowski, Corinna, van der Stam, Lieske, Bongartz, Anke, Enzmann, Cornelia, Fluss, Joël, Galiart, Elea, Jacquier, David, Metzler, Dominique Baumann, Tscherter, Anne, Weiß, Claudia, Becker, Lena-Luise, Friese, Johannes, Blaschek, Astrid, Hahn, Andreas, Illsinger, Sabine, Schwartz, Oliver, Bernert, Günther, Hagen, Maja von der, Flotats-Bastardas, Marina, Schreiber, Gudrun, Schara, Ulrike, Trollmann, Regina, Horber, Veronka, Wilichowski, Ekkehard, Baumann, Matthias, Klein, Andrea, Eisenkölbl, Astrid, Köhler, Cornelia, Stettner, Georg M., Cirak, Sebahattin, Hasselmann, Oswald, Garbade, Sven F., Johannsen, Jessika, and Ziegler, Andreas

Published
2024
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9. Factors Affecting Implant Length in Primary Inflatable Penile Prosthesis Placement

Author

Miller, Jake A., Hammad, Muhammed, Amini, Eliad, Andrianne, Robert, Burnett, Arthur L., Gross, Kelli, Gross, Martin S., Hatzichristodoulou, Georgios, Hotaling, James, Hsieh, Tung-Chin, Jenkins, Lawrence C., Jones, James M., Lentz, Aaron, Levy, Jason, Modgil, Vaibhav, Osmonov, Daniar, Park, Sung Hun, Pearce, Ian, Perito, Paul, Sadeghi-Nejad, Hossein, Sempels, Maxime, Simhan, Jay, Suarez-Sarmiento Jr, Alfredo, van Renterghem, Koenraad, Warner, J. Nicholas, Yafi, Faysal A., Ziegelmann, Matthew, and Barham, David W.

Published
2024
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21. Observing many researchers using the same data and hypothesis reveals a hidden universe of uncertainty

Author

Breznau, Nate, Rinke, Eike Mark, Wuttke, Alexander, Nguyen, Hung H. V., Adem, Muna, Adriaans, Jule, Alvarez-Benjumea, Amalia, Andersen, Henrik K., Auer, Daniel, Azevedo, Flavio, Bahnsen, Oke, Balzer, Dave, Bauer, Gerrit, Bauer, Paul C., Baumann, Markus, Baute, Sharon, Benoit, Verena, Bernauer, Julian, Berning, Carl, Berthold, Anna, Bethke, Felix S., Biegert, Thomas, Blinzler, Katharina, Blumenberg, Johannes N., Bobzien, Licia, Bohman, Andrea, Bol, Thijs, Bostic, Amie, Brzozowska, Zuzanna, Burgdorf, Katharina, Burger, Kaspar, Busch, Kathrin B., Carlos-Castillo, Juan, Chan, Nathan, Christmann, Pablo, Connelly, Roxanne, Czymara, Christian S., Damian, Elena, Ecker, Alejandro, Edelmann, Achim, Eger, Maureen A., Ellerbrock, Simon, Forke, Anna, Forster, Andrea, Gaasendam, Chris, Gavras, Konstantin, Gayle, Vernon, Gessler, Theresa, Gnambs, Timo, Godefroidt, Amélie, Grömping, Max, Groß, Martin, Gruber, Stefan, Gummer, Tobias, Hadjar, Andreas, Heisig, Jan Paul, Hellmeier, Sebastian, Heyne, Stefanie, Hirsch, Magdalena, Hjerm, Mikael, Hochman, Oshrat, Hövermann, Andreas, Hunger, Sophia, Hunkler, Christian, Huth, Nora, Ignácz, Zsófia S., Jacobs, Laura, Jacobsen, Jannes, Jaeger, Bastian, Jungkunz, Sebastian, Jungmann, Nils, Kauff, Mathias, Kleinert, Manuel, Klinger, Julia, Kolb, Jan-Philipp, Kołczyńska, Marta, Kuk, John, Kunißen, Katharina, Sinatra, Dafina Kurti, Langenkamp, Alexander, Lersch, Philipp M., Löbel, Lea-Maria, Lutscher, Philipp, Mader, Matthias, Madia, Joan E., Malancu, Natalia, Maldonado, Luis, Marahrens, Helge, Martin, Nicole, Martinez, Paul, Mayerl, Jochen, Mayorga, Oscar J., McManus, Patricia, McWagner, Kyle, Meeusen, Cecil, Meierrieks, Daniel, Mellon, Jonathan, Merhout, Friedolin, Merk, Samuel, Meyer, Daniel, Micheli, Leticia, Mijs, Jonathan, Moya, Cristóbal, Neunhoeffer, Marcel, Nüst, Daniel, Nygård, Olav, Ochsenfeld, Fabian, Otte, Gunnar, Pechenkina, Anna O., Prosser, Christopher, Raes, Louis, Ralston, Kevin, Ramos, Miguel R., Roets, Arne, Rogers, Jonathan, Ropers, Guido, Samuel, Robin, Sand, Gregor, Schachter, Ariela, Schaeffer, Merlin, Schieferdecker, David, Schlueter, Elmar, Schmidt, Regine, Schmidt, Katja M., Schmidt-Catran, Alexander, Schmiedeberg, Claudia, Schneider, Jürgen, Schoonvelde, Martijn, Schulte-Cloos, Julia, Schumann, Sandy, Schunck, Reinhard, Schupp, Jürgen, Seuring, Julian, Silber, Henning, Sleegers, Willem, Sonntag, Nico, Staudt, Alexander, Steiber, Nadia, Steiner, Nils, Sternberg, Sebastian, Stiers, Dieter, Stojmenovska, Dragana, Storz, Nora, Striessnig, Erich, Stroppe, Anne-Kathrin, Teltemann, Janna, Tibajev, Andrey, Tung, Brian, Vagni, Giacomo, Van Assche, Jasper, van der Linden, Meta, van der Noll, Jolanda, Van Hootegem, Arno, Vogtenhuber, Stefan, Voicu, Bogdan, Wagemans, Fieke, Wehl, Nadja, Werner, Hannah, Wiernik, Brenton M., Winter, Fabian, Wolf, Christof, Yamada, Yuki, Zhang, Nan, Ziller, Conrad, Zins, Stefan, and Żółtak, Tomasz

Published
2022

22. Long-term efficacy and safety of nusinersen in adults with 5q spinal muscular atrophy: a prospective European multinational observational study

Author

Günther, René, Wurster, Claudia Diana, Brakemeier, Svenja, Osmanovic, Alma, Schreiber-Katz, Olivia, Petri, Susanne, Uzelac, Zeljko, Hiebeler, Miriam, Thiele, Simone, Walter, Maggie C., Weiler, Markus, Kessler, Tobias, Freigang, Maren, Lapp, Hanna Sophie, Cordts, Isabell, Lingor, Paul, Deschauer, Marcus, Hahn, Andreas, Martakis, Kyriakos, Steinbach, Robert, Ilse, Benjamin, Rödiger, Annekathrin, Bellut, Julia, Nentwich, Julia, Zeller, Daniel, Muhandes, Mohamad Tareq, Baum, Tobias, Christoph Koch, Jan, Schrank, Bertold, Fischer, Sophie, Hermann, Andreas, Kamm, Christoph, Naegel, Steffen, Mensch, Alexander, Weber, Markus, Neuwirth, Christoph, Lehmann, Helmar C., Wunderlich, Gilbert, Stadler, Christian, Tomforde, Maike, George, Annette, Groß, Martin, Pechmann, Astrid, Kirschner, Janbernd, Türk, Matthias, Schimmel, Mareike, Bernert, Günther, Martin, Pascal, Rauscher, Christian, Meyer zu Hörste, Gerd, Baum, Petra, Löscher, Wolfgang, Flotats-Bastardas, Marina, Köhler, Cornelia, Probst-Schendzielorz, Kristina, Goldbach, Susanne, Schara-Schmidt, Ulrike, Müller-Felber, Wolfgang, Lochmüller, Hanns, von Velsen, Otgonzul, Kleinschnitz, Christoph, Ludolph, Albert C., and Hagenacker, Tim

Published
2024
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25. Single Dilation in Primary Inflatable Penile Prosthesis Placement Is Associated With Fewer Corporal Complications Than Sequential Dilation

Author

Chang, Chrystal, Barham, David W., Dalimov, Zafardjan, Swerdloff, Daniel, Sadeghi-Nejad, Hossein, Andrianne, Robert, Sempels, Maxime, Hsieh, Tung-Chin, Hatzichristodoulou, Georgios, Hammad, Muhammed, Miller, Jake, Osmonov, Daniar, Lentz, Aaron, Perito, Paul, Suarez-Sarmiento, Alfredo, Hotaling, James, Gross, Kelli, Jones, James M., van Renterghem, Koenraad, Park, Sung Hun, Nicholas Warner, J., Ziegelmann, Matthew, Modgil, Vaibhav, Jones, Adam, Pearce, Ian, Gross, Martin S., Yafi, Faysal A., and Simhan, Jay

Published
2023
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38. On the cost of essentially fair clusterings

Author

Bercea, Ioana O., Groß, Martin, Khuller, Samir, Kumar, Aounon, Rösner, Clemens, Schmidt, Daniel R., and Schmidt, Melanie

Subjects
Computer Science - Data Structures and Algorithms
Abstract

Clustering is a fundamental tool in data mining. It partitions points into groups (clusters) and may be used to make decisions for each point based on its group. However, this process may harm protected (minority) classes if the clustering algorithm does not adequately represent them in desirable clusters -- especially if the data is already biased. At NIPS 2017, Chierichetti et al. proposed a model for fair clustering requiring the representation in each cluster to (approximately) preserve the global fraction of each protected class. Restricting to two protected classes, they developed both a 4-approximation for the fair $k$-center problem and a $O(t)$-approximation for the fair $k$-median problem, where $t$ is a parameter for the fairness model. For multiple protected classes, the best known result is a 14-approximation for fair $k$-center. We extend and improve the known results. Firstly, we give a 5-approximation for the fair $k$-center problem with multiple protected classes. Secondly, we propose a relaxed fairness notion under which we can give bicriteria constant-factor approximations for all of the classical clustering objectives $k$-center, $k$-supplier, $k$-median, $k$-means and facility location. The latter approximations are achieved by a framework that takes an arbitrary existing unfair (integral) solution and a fair (fractional) LP solution and combines them into an essentially fair clustering with a weakly supervised rounding scheme. In this way, a fair clustering can be established belatedly, in a situation where the centers are already fixed.

Published
2018

43. Intersektoralität

Author

Demmer, Thomas, Groß, Martin, Rühle, Nicole, Jürgens, Tim P., Junghanß, Christian, Hermann, Andreas, Groß, Martin, editor, and Demmer, Thomas, editor

Published
2021
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