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7 results on '"Groot, M.W."'

2. Non-medical determinants of perinatal health: protocol for a systematic review with meta-analysis

Author

Daalderop, L.A. (Leonie A.), Groot, M.W. (Marjolein) de, van der Meer, L. (Lindsey), Steegers, E.A.P. (Eric), Bertens, L.C.M. (Loes C.M.), Daalderop, L.A. (Leonie A.), Groot, M.W. (Marjolein) de, van der Meer, L. (Lindsey), Steegers, E.A.P. (Eric), and Bertens, L.C.M. (Loes C.M.)

Abstract

INTRODUCTION: Research focusing on the associations between non-medical determinants and unfavourable perinatal health outcomes is increasing. Despite increasing knowledge on this theme, it still remains unclear to what extent social, environmental and lifestyle factors contribute to these unfavourable outcomes. Therefore, we aim to provide a systematic review, preferably with meta-analysis, in order to provide insight into the associations between non-medical determinants and perinatal mortality, preterm birth and being small for gestational age (SGA). METHODS AND ANALYSIS: Observational studies performed in European countries studying the associations between non-medical determinants and unfavourable perinatal health outcomes will be included. Primary outcomes of interest are perinatal mortality, preterm birth and SGA. To retrieve potential eligible articles, a systematic literature search was performed in the following online databases on 5 October 2018: MEDLINE, Embase, Web of Science, Cochrane and Google Scholar. Additionally, a reference list check and citation search will be performed. Data of the included articles will be extracted using a standardised and piloted data extraction form. Risk of bias will be assessed using the Newcastle-Ottawa Scale. The study selection and data extraction process will be performed by two reviewers independently. Disagreements will be resolved through discussion with a third reviewer. The pooled effects will be calculated separately for each association found between one of the outcome measures and the non-medical determinants using a random effects model. Heterogeneity of the studies will be assessed using the I2 statistic. ETHICS AND DISSEMINATION: No ethical approval is necessary for a systematic review with meta-analysis. The findings will be published in a peer-reviewed journal. PROSPERO REGISTRATION NUMBER: CRD42018056105.

Published
2019
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3. Contrast-enhanced computed tomographic evaluation of the deep digital flexor tendon in the equine foot compared to macroscopic and histological findings in 23 limbs

Author

van Hamel, S E, Bergman, H J, Puchalski, S M, Groot, M.W., van Weeren, P R, ES TR, Tissue Repair, Dep Gezondheidszorg Paard, and LS Equine Muscoskeletal Biology

Subjects
Tendons, Foot, Forelimb, Cadaver, Animals, Contrast Media, Horses, Tomography, X-Ray Computed
Abstract

REASONS FOR PERFORMING THE STUDY: Distal deep digital flexor tendinopathy is an important cause of foot lameness in horses that is difficult to diagnose with radiography and ultrasonography. Magnetic resonance imaging is a well-accepted and validated technique for the identification of deep digital flexor tendon (DDFT) lesions, but has some practical and financial drawbacks. Contrast-enhanced computed tomography (CECT) has been proposed as a suitable alternative, but validation studies are currently lacking. OBJECTIVE: To assess the accuracy of CECT for the identification and characterisation of deep digital flexor tendinopathy. STUDY DESIGN: Descriptive study of CT, macroscopic and histological findings of the DDFT. METHODS: Plain and CECT scans were acquired of 23 limbs of 16 horses with clinical lameness localised to the foot. All horses had lesions of the DDFT that were identified and characterised with CT and CECT with respect to their anatomic location and extent. All horses underwent post mortem examination and gross abnormalities were described. Samples of the DDFT were taken at specific sites (lesion and nonlesion) for histological evaluation. Macroscopic and histological outcomes were compared with CECT findings. RESULTS: Of 67 sites in 23 DDFTs that were evaluated, 42 sites in 18 tendons had lesions on CECT images. These 42 sites also had lesions on macroscopic evaluation. There were 3 false negative and 3 false positive results identified on CECT. The sensitivity of CECT for diagnosing lesions of the DDFT in the equine foot was 93%. CONCLUSION: CECT is an effective adjunct to the more commonly used diagnostic techniques in equine foot pain.

Published
2014

4. Achteraf bekeken: Architectuur in Suriname 1951 tot 1969: Bouwwerken ontworpen door ir. P.J. Nagel (1921-1997)

Author

Nagel - de Groot, M.W.

Subjects
bouwkunst, monografie (kunst), architectuur
Abstract

Dit boek bestaat hoofdzakelijk uit foto’s van bouwwerken in Suriname, ontworpen door ir. Peter Jacobus Nagel in de periode 1951-1969. Ingenieur P.J. Nagel is afgestudeerd aan de Technische Hogeschool Delft. In dit boek wordt beschreven het leven van Nagel: zijn studietijd, eerste werkkring op Aruba, leven en werken als zelfstandig architect in Suriname van 1951 tot 1963 en tot slot zijn activiteiten in- en vanuit Nederland.

Published
2005

5. Achteraf bekeken: Architectuur in Suriname 1951 tot 1969: Bouwwerken ontworpen door ir. P.J. Nagel (1921-1997)

Author

Nagel - de Groot, M.W. (author) and Nagel - de Groot, M.W. (author)

Abstract

Dit boek bestaat hoofdzakelijk uit foto’s van bouwwerken in Suriname, ontworpen door ir. Peter Jacobus Nagel in de periode 1951-1969. Ingenieur P.J. Nagel is afgestudeerd aan de Technische Hogeschool Delft. In dit boek wordt beschreven het leven van Nagel: zijn studietijd, eerste werkkring op Aruba, leven en werken als zelfstandig architect in Suriname van 1951 tot 1963 en tot slot zijn activiteiten in- en vanuit Nederland.

Published
2005

6. Acute fasting in heifers as a model for assessing the relationship between plasma and follicular fluid NEFA concentrations

Author

Jorritsma, R., Groot, M.W. de, Vos, P.L.A.M., Kruip, T.A.M., Wensing, Th., and Noordhuizen, J.P.T.M.

Subjects
*HEIFERS, *FATTY acids, *BIOENERGETICS
Abstract

It is known from epidemiological studies that negative energy balance in early lactating dairy cows is related to a depression in reproductive performance. Elevated plasma concentrations of non-esterified fatty acids (NEFA) are a typical metabolic characteristic of these animals and are proposed as the possible link. The suggestion is that NEFA might have a direct effect on the ovary, by affecting development of the oocyte or the granulosa cells. However, no data is available concerning the relationship between the concentration of NEFA in follicular fluid and plasma. Therefore, a cross-over study with 10 heifers around 15 months of age was conducted to analyze this relationship and examine the suggested effects of the negative energy balance on follicular growth. Investigation of these effects was performed on fasted heifers. The experimental treatment consisted of feeding hay with a subsequent period of fasting, to induce elevated plasma NEFA concentrations. Sampling of follicular fluid was performed using transvaginal aspiration of follicles, which were standardized using a synchronization protocol. In addition, concentrations of glucose, insulin, NEFA, and estradiol were measured in plasma. Follicular estradiol and progesterone concentrations were also measured to assess the quality of the dominant follicle. Fasting resulted in significantly lower plasma glucose (P=0.0006) and plasma insulin (P<0.0001) concentrations, higher plasma estradiol (P=0.008) and higher NEFA (P<0.001) concentrations, and smaller follicles (P=0.04) with lower estradiol:progesterone (E/P) ratios (P=0.05). Concentrations of NEFA in follicular fluid and plasma were closely related. Given this close relationship, we concluded that the presence of high plasma NEFA concentrations might link energy metabolism in early lactation with fertility. [Copyright &y& Elsevier]

Published
2003
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