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426 results on '"Groscurth P"'

1. The DBCLS BioHackathon: standardization and interoperability for bioinformatics web services and workflows

Author

Katayama, Toshiaki, Arakawa, Kazuharu, Nakao, Mitsuteru, Ono, Keiichiro, Aoki-Kinoshita, Kiyoko F, Yamamoto, Yasunori, Yamaguchi, Atsuko, Kawashima, Shuichi, Chun, Hong-Woo, Aerts, Jan, Aranda, Bruno, Barboza, Lord, Bonnal, Raoul JP, Bruskiewich, Richard, Bryne, Jan C, Fernández, José M, Funahashi, Akira, Gordon, Paul MK, Goto, Naohisa, Groscurth, Andreas, Gutteridge, Alex, Holland, Richard, Kano, Yoshinobu, Kawas, Edward A, Kerhornou, Arnaud, Kibukawa, Eri, Kinjo, Akira R, Kuhn, Michael, Lapp, Hilmar, Lehvaslaiho, Heikki, Nakamura, Hiroyuki, Nakamura, Yasukazu, Nishizawa, Tatsuya, Nobata, Chikashi, Noguchi, Tamotsu, Oinn, Thomas M, Okamoto, Shinobu, Owen, Stuart, Pafilis, Evangelos, Pocock, Matthew, Prins, Pjotr, Ranzinger, René, Reisinger, Florian, Salwinski, Lukasz, Schreiber, Mark, Senger, Martin, Shigemoto, Yasumasa, Standley, Daron M, Sugawara, Hideaki, Tashiro, Toshiyuki, Trelles, Oswaldo, Vos, Rutger A, Wilkinson, Mark D, York, William, Zmasek, Christian M, Asai, Kiyoshi, and Takagi, Toshihisa

Abstract

Abstract Web services have become a key technology for bioinformatics, since life science databases are globally decentralized and the exponential increase in the amount of available data demands for efficient systems without the need to transfer entire databases for every step of an analysis. However, various incompatibilities among database resources and analysis services make it difficult to connect and integrate these into interoperable workflows. To resolve this situation, we invited domain specialists from web service providers, client software developers, Open Bio* projects, the BioMoby project and researchers of emerging areas where a standard exchange data format is not well established, for an intensive collaboration entitled the BioHackathon 2008. The meeting was hosted by the Database Center for Life Science (DBCLS) and Computational Biology Research Center (CBRC) and was held in Tokyo from February 11th to 15th, 2008. In this report we highlight the work accomplished and the common issues arisen from this event, including the standardization of data exchange formats and services in the emerging fields of glycoinformatics, biological interaction networks, text mining, and phyloinformatics. In addition, common shared object development based on BioSQL, as well as technical challenges in large data management, asynchronous services, and security are discussed. Consequently, we improved interoperability of web services in several fields, however, further cooperation among major database centers and continued collaborative efforts between service providers and software developers are still necessary for an effective advance in bioinformatics web service technologies.

Published
2010

10. Architecture of arachnoid trabeculae, pillars, and septa in the subarachnoid space of the human optic nerve: anatomy and clinical considerations. (Laboratory Science)

Author

Killer, H.E., Laeng, H.R., Flammer, J., and Groscurth, P.

Subjects
Physiological aspects, Research, Optic nerve -- Physiological aspects -- Research, Ophthalmology -- Research -- Physiological aspects
Abstract

Aims: To describe the anatomy and the arrangement of the arachnoid trabeculae, pillars, and septa in the subarachnoid space of the human optic nerve and to consider their possible clinical [...]

Published
2003

29. Clinical Experience with Preoperative Chemotherapy for Osteosarcoma

Author

Honegger, H. P., Cserhati, M., von Hochstetter, A. R., Hofmann, V., Groscurth, P., Herfarth, Ch., editor, Senn, H.-J., editor, Baum, M., editor, von Essen, C., editor, Diehl, V., editor, Hitzig, W., editor, Rajewsky, M. F., editor, Thomas, C., editor, Metzger, Urs, editor, Largiadèr, Felix, editor, and Senn, Hans-Jörg, editor

Published
1985
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31. Advanced training model for beating heart coronary artery surgery: the Zurich heart-trainer

Author

Reuthebuch, O., Lang, A., Groscurth, P., Lachat, M., Turina, M., Zünd, G., Reuthebuch, O., Lang, A., Groscurth, P., Lachat, M., Turina, M., and Zünd, G.

Abstract

Objective: Coronary artery surgery with beating heart technique is gaining increasing popularity. However, it is a challenging technique even for well-trained cardiac surgeons. Thus, a training model for beating heart surgery was developed to increase safety and accuracy of this procedure. Methods: The model consists of differentially hardened polyurethane resembling mechanical properties of the human heart. The covering used in this model is a 1:1 replica of the human thoracic wall with optionally embedded skeletal structures. Sternotomy, lateral thoracotomy or trocar placement is possible to access the lungs, the pericardium and the heart with adjacent vessels. Disposable artificial coronaries variable in size, wall quality or wall thickness are embedded in the synthetic myocardium. Two-layer vessels, which can simulate dissection, are available. Bypass conduits utilize the same material. Coronaries/bypasses as well as part of the ascending aorta are water-tight and can be rinsed with saline. Lungs can be inflated. A purpose-built pump induces heart movement with adjustable or randomized stroke volume, heart rate and arrhythmia induction. Results: The model was tested in a recent ‘Wet-Lab' course attended by 30 surgeons. All conventional instruments and stabilizers with standard techniques can be used. Training with beating or non-beating heart was possible. Time needed for an anastomosis was similar to clinical experience. Each artificial tissue showed its individual nature-like qualities. Various degrees of difficulty can be selected, according to stroke volume, heart rate, arrhythmia, vessel size and vessel quality. The model can be quickly and easily set up and is fully reusable. Conclusions: The similarity to human tissue and the easy set-up make this completely artificial model an ideal teaching tool to increase the confidence of cardiac surgeons dealing with beating heart and minimally invasive surgery

Published
2017

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