Search

Objective To explore the postmortem diffusion rule of Aconitum alkaloids and their metabolites in poisoned rabbits, and to provide a reference for identifying the antemortem poisoning or postmortem poisoning of Aconitum alkaloids. Methods Twenty-four rabbits were sacrificed by tracheal clamps. After 1 hour, the rabbits were administered with aconitine LD50 in decocting aconite root powder by intragastric administration. Then, they were placed supine and stored at 25 ℃. The biological samples from 3 randomly selected rabbits were collected including heart blood, peripheral blood, urine, heart, liver, spleen, lung and kidney tissues at 0 h, 4 h, 8 h, 12 h, 24 h, 48 h, 72 h and 96 h after intragastric administration, respectively. Aconitum alkaloids and their metabolites in the biological samples were analyzed by high performance liquid chromatography-tandem mass spectrometry （HPLC-MS/MS）. Results At 4 h after intragastric administration, Aconitum alkaloids and their metabolites could be detected in heart blood, peripheral blood and major organs, and the contents of them changed dynamically with the preservation time. The contents of Aconitum alkaloids and their metabolites were higher in the spleen, liver and lung, especially in the spleen which was closer to the stomach. The average mass fraction of benzoylmesaconine metabolized in rabbit spleen was the highest at 48 h after intragastric administration. In contrast, the contents of Aconitum alkaloids and their metabolites in kidney were all lower. Aconitum alkaloids and their metabolites were not detected in urine. Conclusion Aconitum alkaloids and their metabolites have postmortem diffusion in poisoned rabbits, diffusing from high-content organs （stomach） to other major organs and tissues as well as the heart blood. The main mechanism is the dispersion along the concentration gradient, while urine is not affected by postmortem diffusion, which can be used as the basis for the identification of antemortem and postmortem Aconitum alkaloids poisoning.

This study investigated visual arts college students' perceptions of the gender stereotyping of creativity and the influence of this stereotyping on creative self-efficacy. The sample consisted of 1198 Chinese visual arts college students. The results showed that (a) both male and female students identified stereotypically masculine traits as more important to creativity than stereotypically feminine traits are, (b) male students demonstrated higher creative self-efficacy than their female counterparts did, and (c) students' gender significantly moderated the effect of the gender stereotyping of creativity on creative self-efficacy. Specifically, the gender stereotyping of creativity had a positive effect on male students and a negative effect on female students. These findings revealed that gender stereotypes dominate concepts of creativity in Chinese art education and may hinder female students' development of creative self-efficacy, resulting in gendered inequality in the visual arts field. The implications of these findings for visual arts education in China are discussed.

This ethnographic case study explored the benefits associated with culturally responsive art learning experience in a Chinese rural town in the process of urbanisation. The case of this study, Fuchong Art Education Programme (FAEP), provided culturally relevant art activities for primary and secondary rural students who cannot access enriched art programmes in schools. Art studio learning, a summer art camp, an art exhibition, neighbourhood sketching, online teaching, student home visits and teacher meetings were documented and examined over an eight-month period of fieldwork. Semi-structured interviews with the participating students, their teachers and parents and the programme coordinator were conducted to elicit the participants' perspectives on the FAEP experience, the benefits of participation and the challenges involved in implementing a culturally responsive art programme. The emerging themes included artistic, personal, social and external benefits, which were examined in relation to previous research on the intrinsic and instrumental benefits of art learning and a local understanding of the value of community art engagement in the lives of rural people. The implications offer guidance for promoting culturally responsive art learning in rural settings.

A multicultural approach has been advocated in school music education in China to heighten the sense of ethnic identity among students from diverse backgrounds, but research has shown that inadequate teaching approaches have been a major challenge in implementing multiculturalism. To facilitate students' development of their sense of ethnic and cultural identity, international educators have advocated the use of culturally responsive teaching (CRT), which can provide Chinese teachers with pedagogical guidance to put multiculturalism into practice. A mixed methods intervention approach was adopted to explore the impact of CRT on the ethnic identities of Yi, Han, Mongolian and Tibetan students in a multi-ethnic school in Sichuan Province, China. The quantitative results revealed that after participating in the CRT music course, the students demonstrated statistically significant improvement across the four dimensions of ethnic identity. The qualitative findings attributed the improvement in the students' ethnic identities to the use of ethnic music and native languages, multiple roles of the local music teacher and collective musical engagement. This study contributes to research on pedagogical strategies that help facilitate cultural diversity in school music education in China, and it serves as a reference for the use of CRT worldwide.

The value of intercultural music learning on intergroup attitudes has been demonstrated in the literature, such as enhancing intercultural sensitivity and building interethnic friendships. However, the process by which intercultural music learning influences intergroup attitudes has not yet been illuminated. This study investigated the impact of an intercultural music course on intergroup attitudes among middle school students (N = 277) from Yi, Han, Mongolian and Tibetan ethnic groups in a multi-ethnic school in Sichuan province, southwest China. The research tools included questionnaire surveys, reflective journals, semi-structured interviews and observational field notes. The findings revealed that the intercultural music course significantly improved the students' intergroup attitudes compared with the regular and non-music courses. The findings further identified six process dimensions that helped capture the gradual changes in students' attitudes towards other groups as well as the cumulative nature of the effects of intercultural music learning. This study sheds light on approaches to using music to learn about, communicate with and appreciate other cultures.

This metadata-based literature study provides a comprehensive mapping of China's music education by analysing 3,257 Chinese research articles published during 2007-2019. The selection of the articles is based on careful inspections of the China National Knowledge Infrastructure (CNKI) database and rigorous coding of literature attributes. The analysis of descriptive and analytical attributes showed (a) dominance of qualitative over quantitative/mixed-method research paradigm, (b) a strong preference for conceptual over empirical studies and (c) a policy-reinforced research orientation. The prime inference from the findings also raised concerns on several 'neglected' research areas and quality issues in the selected literature.

In recent years, the survival of patients increased with development of treatment modalities for hepatocellular carcinoma(HCC). However, the incidence of distant metastasis was gradually increasing to make the prognosis of patients with HCC worse. Lungs are the most common distant metastatic organs from HCC. Therapy of pulmonary metastasis from HCC was still disappointing with the median overall survival less than 1 year for individual differences in patients and tumor heterogeneity. Currently, there was without standard treatment for pulmonary metastases from HCC, and the patients were treated according to the treatment guidelines of advanced HCC combined with lung cancer. Although studies on invasion and metastasis of HCC emerged in a few decades, the detail pathogenesis of lung metastasis remains unclear. This article will summarize the pathogenesis and therapeutic advances of pulmonary metastasis from HCC and emphasize the importance of intrahepatic lesion control and management of pulmonary metastases.

The question of how to better prepare ethnic minority students to access higher music education has raised concerns around the world in terms of educational equity and cultural diversity. In China, despite similar concerns, little is known about the preparation process and experiences of ethnic minority students to take the Music College Entrance Examination (MCEE). In this qualitative case study, we investigated the facilitators and barriers faced by 22 high school students of Yi, Mongolian and Tibetan backgrounds while preparing for the MCEE in a multi-ethnic school in Sichuan province, southwestern China. The methods included participant observation and semi-structured interviews. The facilitators identified in the study were support from family members, local teachers' devotion, positive peer influences and nationally renowned ethnic musicians as role models. The five main barriers were financial difficulties, parents' misconception of the value of the MCEE, limited expertise of local music teachers, exam-oriented school climate and the MCEE's structure based on Western classical music. Based on the findings, suggestions for adopting affirmative action and reforming the structure of the MCEE are proposed. [ABSTRACT FROM AUTHOR]

Relying on Longqiao dump project, due to the high water content in the dump slope, it can not accumulate into a high slope dump. The critical slip field method is used to search the most dangerous slip surface of the slope for the slope of the waste dump. The stacking method of the waste dump is proposed. Combined with the Geo-Slope software, the safety factors under the stability evaluation of Ordinary, Janbu and Bishop are obtained. The research results show that the slope reinforced by reinforced gabion has high stability, which solves the problem of safe stacking and discharging of the waste rock and provides guarantee for the safe mining of the mine.

ObjectivePsychological distress such as depression and anxiety resulted from coronavirus disease 2019 (COVID-19) have attracted increasing attention. The aim of this randomized controlled trial is to evaluate the effects and safety of auricular acupressure on depression and anxiety in isolated COVID-19 patients.Methods68 participants diagnosed with COVID-19 pneumonia (18–80 years old, SDS ≥ 50, SAS ≥ 45) were recruited and randomly allocated to the auricular acupressure group and the sham auricular acupressure group by a computer-generated random number sequence from 9th June to 30th June 2022. The group allocation was only blinded to the participants. Those in the auricular acupressure group were attached magnetic beads against 4 auricular points Shenmen, Subcortex, Liver and Endocrine, while sham group used four irrelevant auricular points. Outcomes were measured by Zung Self-Rating Depression Scale (SDS) and Zung Self-Rating Depression Scale (SAS) before and after treatment in both groups through electronic questionnaire in mobile phones.ResultsAfter treatment, statistically significant differences were found in scores of SAS in both groups (P < 0.001 in auricular acupressure group; P = 0.003 in sham group), and SDS scores reduced significantly in the auricular acupressure group (P = 0.002). Significant reduced SAS and SDS scores were achieved in the auricular acupressure group than that in the sham group (F = 4.008, P = 0.049, MD −7.70 95% CI: −9.00, −6.40, SMD −2.79 95% CI: −3.47, −2.11 in SDS; F = 10.186, P = 0.002, MD −14.00 95% CI: −15.47, −12.53, SMD −4.46 95% CI: −5.37, −3.56 in SAS). No adverse events were found in either group during the whole study.ConclusionAuricular acupressure is an effective and safe treatment for alleviating symptoms of depressive and anxiety in patients with COVID-19.Clinical trial registrationhttps://www.chictr.org.cn//, identifier ChiCTR2200061351.